Stem Cell Res 2022 05 14;61:102751. Epub 2022 Mar 14.
Department of Urology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China; Engineering Laboratory of Urinary Organ and Functional Reconstruction of Shandong Province, Jinan, China; Binzhou Medical University, Yantai, China. Electronic address:
Glomerulopathy with fibronectin deposits (GFND) is an autosomal dominant kidney disease exhibiting microscopic hematuria, proteinuria, and hypertension that may lead to end-stage renal failure. In this study, using non-integrative episomal vectors an induced pluripotent stem cell (iPSC) line, FHUSTCi001-A, was derived from peripheral blood mononuclear cells of an 11-year-old boy with GFND carrying a heterozygous c.5602G > A (p. Read More