992 results match your criteria Glomerulonephritis Diffuse Proliferative


Association of hemophagocytic lymphohistiocytosis with kidney lesions in acute African swine fever virus infection

Ann Parasitol 2018 ;64(4):343-350

Department of Medical Biology and Parasitology, Armenia Yerevan State Medical University, 2 Koryun St., Yerevan 0025, Armenia

Glomerulonephritis due to African swine fever (ASF) is well documented. However, there is absence of good understanding of mechanisms involved in the development of pathology development. This study examines glomerulonephritis in association with acute infection induced by II genotype (Georgia 2007) of ASF virus. Read More

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January 2018
1 Read

A case of aggressive atypical anti-GBM disease complicated by CMV pneumonitis.

BMC Nephrol 2019 Jan 31;20(1):29. Epub 2019 Jan 31.

Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Foothills Medical Center, 1403 29 St NW, Calgary, AB, T2N 2T9, Canada.

Background: Anti-glomerular basement membrane (anti-GBM) disease is characterized by circulating IgG glomerular basement membrane antibodies and is clinically expressed as a rapidly progressive crescentic glomerulonephritis (GN), with 30-60% of patients also developing pulmonary hemorrhage. Classically, the renal biopsy shows glomerular crescent formation, bright linear staining of glomerular basement membranes (GBM) for IgG on direct immunofluorescence (IF), and the serologic presence of circulating anti-GBM antibodies. Recently, patients with linear IgG IF staining, undetectable circulating anti-GBM antibodies and glomerular changes atypical for anti-GBM disease have been described as "atypical anti-GBM disease", with a distinctly more benign clinical course than typical anti-GBM disease. Read More

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http://dx.doi.org/10.1186/s12882-019-1227-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357502PMC
January 2019
2 Reads

Analysis of native kidney biopsy: Data from a single center from Bihar, India.

Saudi J Kidney Dis Transpl 2018 Sep-Oct;29(5):1174-1180

Department of Nephrology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.

This is a retrospective study of all native kidney biopsies performed at our center between October 1, 2012 and March 31, 2015. Relevant clinical and laboratory variables were recorded. Biopsy samples were processed for light microscopy and immunofluorescence in all cases. Read More

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http://www.sjkdt.org/text.asp?2018/29/5/1174/243975
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http://dx.doi.org/10.4103/1319-2442.243975DOI Listing
November 2018
4 Reads

A Case of Hepatic Glomerulosclerosis with Monoclonal IgA1- Deposits.

Case Rep Nephrol 2018 1;2018:4748357. Epub 2018 Oct 1.

Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Glomerular immunoglobulin A (IgA) deposition is a common finding in hepatic glomerulosclerosis; thus, this disease is also called hepatic IgA nephropathy. However, only a small number of patients with hepatic IgA nephropathy have active glomerular lesions, so functional decline is slow in most cases. In this report, we describe a 60-year-old man who developed nephrotic syndrome and progressive renal impairment during follow-up for alcoholic liver cirrhosis. Read More

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https://www.hindawi.com/journals/crin/2018/4748357/
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http://dx.doi.org/10.1155/2018/4748357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188736PMC
October 2018
12 Reads

Clinicopathological features and outcome of antibody-negative anti-glomerular basement membrane disease.

J Clin Pathol 2019 Jan 12;72(1):31-37. Epub 2018 Oct 12.

National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China

Aim: To explore the clinicopathological characteristics of patients with anti-GBM antibody-negative anti-GBM disease.

Methods: The clinical and renal pathological findings were retrospectively studied in 19 patients. All patients met the following inclusion criteria: linear GBM IgG deposition on immunofluorescence(IF); and lack of serum anti-GBM antibodies by ELISA and indirect immunofluorescence assay. Read More

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http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2018-205278
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http://dx.doi.org/10.1136/jclinpath-2018-205278DOI Listing
January 2019
13 Reads
2.920 Impact Factor

New-onset lupus nephritis after male-to-female sex reassignment surgery.

Lupus 2018 Nov 19;27(13):2166-2169. Epub 2018 Sep 19.

Nephrology Service, Cassiano Antonio Moraes University Hospital, Federal University of Espírito Santo (HUCAM-UFES), Vitória (ES), Brazil.

We report an original case of a 27-year-old transgender woman who developed lupus nephritis after male-to-female sex reassignment surgery. The patient had been taking hormones to induce feminization since the age of 18. She was admitted with malar "butterfly" rash, anasarca and hypertension, associated with an increase in serum creatinine (1. Read More

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http://dx.doi.org/10.1177/0961203318800571DOI Listing
November 2018
3 Reads

Standardized classification and reporting of glomerulonephritis.

Nephrol Dial Transplant 2019 Feb;34(2):193-199

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.

A kidney biopsy is done to determine the etiology of the glomerulonephritis (GN) and the severity of the lesion, to identify whether other lesions, related to or not related to the GN, are present on the kidney biopsy and finally to ascertain the extent of chronicity of the GN. The etiology of GN is based on the classification of GN into five groups: immune complex-mediated GN, antineutrophil cytoplasmic antibody (ANCA)-associated GN, anti-glomerular basement membrane (GBM) GN, monoclonal immunoglobulin-mediated GN and C3 glomerulopathy. Immune complex GN includes multiple specific diseases such as lupus nephritis, IgA nephropathy, infection-related GN and fibrillary GN. Read More

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http://dx.doi.org/10.1093/ndt/gfy220DOI Listing
February 2019
7 Reads

Late-Onset Systemic Lupus Erythematosus With Lupus Nephritis in a 74-Year-Old Male: A Brief Case and Review.

Can J Kidney Health Dis 2018 6;5:2054358118793397. Epub 2018 Aug 6.

Department of Nephrology, Kingston General Hospital, Queen's University, ON, Canada.

Rationale: Late-onset systemic lupus erythematosus (SLE) represents a specific subgroup of SLE, and although there is no strict age cut-off, 50 years is commonly used as the minimum age for disease onset. In this report, we present a case of a 74-year-old male with late-onset SLE and biopsy-proven lupus nephritis (LN).

Presenting Concerns Of The Patient: A 74-year-old male was referred to the nephrology clinic with a rapidly rising creatinine from a baseline of 60 µmol/L to 176 µmol/L. Read More

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http://dx.doi.org/10.1177/2054358118793397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081753PMC
August 2018
3 Reads

Acute infection-related glomerulonephritis with disseminated gonococcal infection in a 13-year-old girl.

BMJ Case Rep 2018 Jul 18;2018. Epub 2018 Jul 18.

Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York, USA.

Infection-related glomerulonephritis results from glomerular immune complex deposition due to a variety of potential pathogens. Poststreptococcal glomerulonephritis is the best known example. We present a case of acute infection-related glomerulonephritis associated with disseminated gonococcal infection in a sexually active 13-year-old girl, the first report of such an association in the absence of endocarditis. Read More

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http://dx.doi.org/10.1136/bcr-2018-225371DOI Listing
July 2018
5 Reads

Proliferative glomerulonephritis with unusual microlamellar organized deposits related to monoclonal immunoglobulin G3 (IgG3) kappa.

CEN Case Rep 2018 Nov 9;7(2):320-324. Epub 2018 Jul 9.

Department of Nephrology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.

A 71-year-old woman presented with massive proteinuria and microhematuria. Renal biopsy showed diffuse global membranoproliferative and endocapillary proliferative lesions with leukocytic infiltration and an irregular duplication of the glomerular basement membrane on light microscopy. Immunofluorescence study showed granular deposits of monoclonal immunoglobulin G3 (IgG3) kappa, C3, and C1q in the glomeruli. Read More

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http://dx.doi.org/10.1007/s13730-018-0351-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181896PMC
November 2018
3 Reads

Patients affected by a new variant of endemic pemphigus foliaceus have autoantibodies colocalizing with MYZAP, p0071, desmoplakins 1-2 and ARVCF, causing renal damage.

Clin Exp Dermatol 2018 Aug 16;43(6):692-702. Epub 2018 May 16.

Department of Clinical Laboratory and Pathology, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia.

Background: We have previously reported that about 30% of patients affected by a new variant of endemic pemphigus foliaceus (EPF) in El Bagre, Colombia (termed El Bagre-EPF or pemphigus Abreu-Manu) have systemic compromise. In the current study, we focused on studying autoreactivity to the kidney and its pathological correlations.

Aim: To investigate patients with El Bagre-EPF for renal compromise. Read More

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http://dx.doi.org/10.1111/ced.13566DOI Listing
August 2018
20 Reads
1.234 Impact Factor

Rapid and Complete Remission of Class IV Lupus Nephritis with Massive Wire Loop Lesions.

Case Rep Nephrol Dial 2018 Jan-Apr;8(1):56-61. Epub 2018 Mar 22.

Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.

Class IV lupus nephritis (LN) often has a poorer prognosis than other classes. However, class IV LN has various phenotypes, including not only segmental and global types but also others. We present the case of a 29-year-old woman with class IV-G LN who had an early response to glucocorticoid monotherapy. Read More

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http://dx.doi.org/10.1159/000487920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903134PMC
March 2018
5 Reads

Bilateral Diffuse and Cluster Pigment Epithelial Detachment Associated with Diffuse Proliferative Glomerulonephritis.

Case Rep Ophthalmol Med 2018 21;2018:5474696. Epub 2018 Feb 21.

Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Retinal pigment epithelium detachment (PED) is an area of retinal pigment epithelium (RPE) elevation with minimal or no sensory retinal detachment resulting from the accumulation of sub-RPE fluid. There are many etiological factors that lead to the development of PED. PED may be observed as an isolated finding or in association with ocular and systemic conditions. Read More

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http://dx.doi.org/10.1155/2018/5474696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841106PMC
February 2018
6 Reads

Staphylococcus Infection-Associated Glomerulonephritis in a Kidney Transplant Patient: Case Report.

Transplant Proc 2018 Apr;50(3):853-856

Urology and Kidney Transplantation Department, Coimbra's University Hospital Center, Coimbra, Portugal.

Background: Staphylococcus infection-associated glomerulonephritis is a rare cause of graft dysfunction in kidney transplant. Suspicion should be high in the setting of elevation of serum creatinine, active urinary sediment, with or without hypocomplementemia, and simultaneous Staphylococcus aureus infection. A kidney biopsy is usually diagnostic. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.02.005DOI Listing

Nephritis-associated plasmin receptor (NAPlr) positive glomerulonephritis caused by Aggregatibacter actinomycetemcomitans bacteremia: A case report.

Clin Nephrol 2018 Aug;90(2):155-160

Infection-related glomerulonephritis (IRGN) develops after various infections. It was previously thought to be caused by Streptococcus species alone but can also be caused by other pathogens. Nephritis-associated plasmin receptor (NAPlr) was discovered as a candidate nephritis-inducing factor in acute post-streptococcal glomerulonephritis. Read More

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http://dx.doi.org/10.5414/CN109173DOI Listing
August 2018
9 Reads

TAFRO syndrome with refractory thrombocytopenia responding to tocilizumab and romiplostim: a case report.

CEN Case Rep 2018 May 21;7(1):162-168. Epub 2018 Feb 21.

Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu-ku, Kawasaki, Kanagawa, Tokyo, 213-8587, Japan.

Thrombocytopenia, anasarca, fever, reticulin fibrosis, organomegaly (TAFRO) syndrome is a unique clinicopathologic subtype of multicentric Castleman's disease that has recently been identified in Japan. However, little is known about its renal histological changes and the optimal treatment for TAFRO syndrome. An 80-year-old Japanese woman was admitted to our hospital for evaluation of severe anasarca and weight gain (10 kg in a month). Read More

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http://dx.doi.org/10.1007/s13730-018-0319-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886949PMC
May 2018
19 Reads

Post-infectious acute glomerulonephritis with podocytopathy induced by parvovirus B19 infection.

Pathol Int 2018 Mar 19;68(3):190-195. Epub 2018 Feb 19.

Division of Rheumatology, Department of Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

Human parvovirus B19 infection causes a variety of glomerular diseases such as post-infectious acute glomerulonephritis and collapsing glomerulopathy. Although each of these appears independently, it has not been fully determined why parvovirus B19 provokes such a variety of different glomerular phenotypes. Here, we report a 68-year-old Japanese man who showed endocapillary proliferative glomerulonephritis admixed with podocytopathy in association with parvovirus B19 infection. Read More

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http://dx.doi.org/10.1111/pin.12643DOI Listing
March 2018
8 Reads

Primary Psychiatric Disorder Masking the Diagnosis of Neuropsychiatric Lupus in a Patient with Altered Mental Status: A Case Report.

Cureus 2017 Oct 23;9(10):e1793. Epub 2017 Oct 23.

GME, Aventura Hospital and Medical Center.

Neuropsychiatric systemic lupus erythematosus (NPSLE) has a wide variety of neurologic and psychiatric features. NPSLE symptoms and the psychotic features of primary psychiatric disorders often overlap with each other. These psychotic features often mask and delay the diagnosis of NPSLE. Read More

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http://dx.doi.org/10.7759/cureus.1793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794200PMC
October 2017
14 Reads

[Renal Involvement in Connective Tissue Diseases].

Dtsch Med Wochenschr 2018 Jan 22;143(2):89-100. Epub 2018 Jan 22.

Renal involvement is common and heterogenous in connective tissue diseases and has a main influence on prognosis and mortality. In systemic lupus erythematosus proliferative glomerulonephritis is the most common manifestation, while in primary Sjogren's syndrome interstitial nephritis with tubular dysfunction is the predominant pathological feature. In systemic sclerosis the most serious renal manifestation is scleroderma renal crisis characterized by abrupt onset of hypertension and acute kidney injury associated with an increase in plasma renin activity. Read More

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http://dx.doi.org/10.1055/s-0043-106563DOI Listing
January 2018
6 Reads

Cetuximab-Associated Crescentic Diffuse Proliferative Glomerulonephritis.

Case Rep Nephrol 2017 16;2017:7964015. Epub 2017 Nov 16.

Southern Illinois University, Springfield, IL, USA.

Cetuximab-induced nephrotoxicity is very rare, occurring in less than 1% of colorectal cancer patients and not defined in other populations. We report a rare case of crescentic diffuse proliferative glomerulonephritis (GN) that developed in close temporal association with cetuximab treatment. A 65-year-old female recently completed chemotherapy with cetuximab treatment for moderately differentiated oral squamous cell carcinoma. Read More

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http://dx.doi.org/10.1155/2017/7964015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733935PMC
November 2017
7 Reads

Atypical antiglomerular basement membranes disease with nephrotic-range proteinuria, mesangial proliferation, and membranoproliferative glomerulonephritis pattern of injury.

Saudi J Kidney Dis Transpl 2017 Nov-Dec;28(6):1397-1403

Department of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Antiglomerular basement membrane (anti-GBM) disease is an uncommon autoimmune disease characterized by the presence of IgG autoantibodies targeting the alpha-3 chain of type IV collagen. Some of the atypical forms of the disease have been described. Herein, we describe a case of atypical anti-GBM in a 27-year-old Saudi male who presented with lower limb edema, gross hematuria, elevated serum creatinine concentration, and nephrotic-range proteinuria. Read More

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http://www.sjkdt.org/text.asp?2017/28/6/1397/220868
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http://dx.doi.org/10.4103/1319-2442.220868DOI Listing
December 2017
16 Reads

IgA-dominant Infection-related Glomerulonephritis in India: A Single-center Experience.

Indian J Nephrol 2017 Nov-Dec;27(6):435-439

Department of Nephrology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, Tamil Nadu, India.

IgA-dominant infection-related glomerulonephritis (IRGN) is a distinct morphologic variant of IRGN, characterized by dominant or codominant glomerular deposits of IgA, mostly in elderly and patients with diabetes. More cases are being reported in recent times due to increased awareness of the disease entity and increased rate of infection. It usually presents as rapidly progressive renal failure with proteinuria, and treatment guidelines for this disease entity are not well defined. Read More

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http://dx.doi.org/10.4103/ijn.IJN_337_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704407PMC
December 2017
14 Reads

A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features.

Case Rep Nephrol 2017 25;2017:1027376. Epub 2017 Oct 25.

Department of Nephrology, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan.

In 2004, the novel category of monoclonal IgG deposition disease has been proposed and termed "proliferative glomerulonephritis with monoclonal IgG deposits" (PGNMID). This disease is characterized by membranoproliferative glomerulonephritis and staining for a single light-chain isotype and gamma heavy-chain subclass. A 76-year-old male who had monoclonal gammopathy was referred to our hospital because of proteinuria. Read More

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http://dx.doi.org/10.1155/2017/1027376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676379PMC
October 2017
11 Reads

Proliferative Diffuse Glomerulonephritis in Rheumatoid Arthritis.

J Clin Rheumatol 2018 Mar;24(2):103-104

Section of Rheumatology and Autoimmune Diseases Hospital JB Iturraspe Santa Fe, Argentina. Section of Nephrology Hospital JB Iturraspe Santa Fe, Argentina

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http://dx.doi.org/10.1097/RHU.0000000000000637DOI Listing
March 2018
8 Reads

Membranoproliferative glomerulonephritis with unusual deposits of parallel arrangement striated structure: a new pathological entity?
.

Clin Nephrol 2018 Feb;89(2):123-129

A 71-year-old male with a past history of lower limb arteriosclerosis obliterans developed nephrotic syndrome and renal dysfunction. Renal biopsy showed diffuse global endocapillary proliferative lesions with infiltration of mononuclear cells and occasional foam cells. An irregular double contour of the glomerular basement membrane and global mild-to-moderate mesangial proliferative lesions were observed, indicating membranoproliferative glomerulonephritis. Read More

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http://dx.doi.org/10.5414/CN109169DOI Listing
February 2018
15 Reads

Kidney Disease in Human Immunodeficiency Virus-seropositive Patients: Absence of Human Immunodeficiency Virus-associated Nephropathy was a Characteristic Feature.

Indian J Nephrol 2017 Jul-Aug;27(4):271-276

Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Human immunodeficiency virus (HIV) infection can cause a broad spectrum of renal diseases. However, there is paucity of Indian data on the patterns of renal lesions in HIV-seropositive patients. The aim of the present study was to delineate the spectrum of renal lesions in HIV/acquired immunodeficiency syndrome patients. Read More

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http://dx.doi.org/10.4103/0971-4065.202400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514822PMC
August 2017
9 Reads

Crescentic glomerular nephritis associated with rheumatoid arthritis: a case report.

J Med Case Rep 2017 Jul 21;11(1):197. Epub 2017 Jul 21.

University Medical Unit, National Hospital of Sri Lanka, Colombo 10, Colombo, Sri Lanka.

Background: Rheumatoid arthritis is a systemic disorder where clinically significant renal involvement is relatively common. However, crescentic glomerular nephritis is a rarely described entity among the rheumatoid nephropathies. We report a case of a patient with rheumatoid arthritis presenting with antineutrophil cytoplasmic antibody-negative crescentic glomerular nephritis. Read More

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http://dx.doi.org/10.1186/s13256-017-1346-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521117PMC
July 2017
7 Reads

Renal tubular epithelial cell-derived BAFF expression mediates kidney damage and correlates with activity of proliferative lupus nephritis in mouse and men.

Lupus 2018 Feb 28;27(2):243-256. Epub 2017 Jun 28.

1 Department of Internal Medicine I, Division of Rheumatology and Clinical Immunology, University Medical Center of the Johannes Gutenberg University Mainz, Germany.

B-cell activating factor of the tumour necrosis factor family (BAFF) is a cytokine, mainly produced by hematopoietic cells (e.g. monocytes/macrophages, dendritic cells), indispensable for B-cell maturation. Read More

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http://dx.doi.org/10.1177/0961203317717083DOI Listing
February 2018
34 Reads

Mycophenolate Mofetil: A Possible Alternative Treatment for IgA Nephropathy.

Contrib Nephrol 2017 23;190:108-116. Epub 2017 May 23.

IgA nephropathy (IgAN) is the most common primary glomerulonephritis in developed countries and a leading cause of chronic kidney disease. IgAN is a mesangial proliferative glomerulonephritis characterized by diffuse mesangial deposition of IgA, often accompanied by the deposition of IgG and the C3 component of complement in a similar distribution. This condition is in most cases oligosymptomatic, often discovered coincidentally. Read More

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http://dx.doi.org/10.1159/000468955DOI Listing
March 2018
42 Reads

Post-infectious Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Deposits Associated with Complement Factor H Mutation.

Intern Med 2017 1;56(7):811-817. Epub 2017 Apr 1.

Department of Nephrology, Shuuwa General Hospital, Japan.

A 55-year-old man developed rapidly progressive glomerulonephritis and nephrotic syndrome. A kidney biopsy specimen showed diffuse proliferative and crescentic glomerulonephritis with monoclonal IgG1κ, humps, and nephritis-associated plasmin receptor, indicating infection-associated proliferative glomerulonephritis with monoclonal immunoglobulin G deposits (PGNMID). Despite dialysis-dependent renal failure, symptomatic therapy resulted in spontaneous recovery of the renal function, mimicking post-infectious glomerulonephritis (PIGN). Read More

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http://dx.doi.org/10.2169/internalmedicine.56.7778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457925PMC
June 2017
13 Reads

Disseminated penicilliosis due to Penicillium chrysogenum in a pediatric patient with Henoch-Schönlein syndrome.

Int J Infect Dis 2016 Oct 3;51:78-80. Epub 2016 Sep 3.

Department of Microbiology, ENCB, Instituto Politécnico Nacional, Mexico City, Mexico.

A case of disseminated infection caused by Penicillium chrysogenum in a 10-year-old boy with a history of Henoch-Schönlein purpura and proliferative glomerulonephritis, treated with immunosuppressors, is reported herein. The patient had a clinical picture of 2 weeks of fever that did not respond to treatment with broad-spectrum antibiotics and amphotericin B. Computed tomography imaging showed diffuse cotton-like infiltrates in the lungs, hepatomegaly, mesenteric lymphadenopathy, and multiple well-defined round hypodense lesions in the spleen. Read More

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http://dx.doi.org/10.1016/j.ijid.2016.08.026DOI Listing
October 2016
19 Reads

A clinicopathologic study of glomerular disease: A single-center, five-year retrospective study from Northwest India.

Saudi J Kidney Dis Transpl 2016 Sep-Oct;27(5):997-1005

Department of Nephrology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.

Studies published from centers across India have reported different and contradicting patterns of glomerular disease. In this retrospective study, we report our experience from a Tertiary Care Center in Northwest India. A total of 702 renal biopsies performed between 2008 and 2013 were reviewed of which 80 were excluded from the study because of having insufficient records or if the biopsies were taken from an allograft. Read More

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http://dx.doi.org/10.4103/1319-2442.190876DOI Listing
August 2017
17 Reads

Response to comments from Fujinaga and Nishino regarding the article "Long-term renal outcomes of childhood-onset global and segmental diffuse proliferative lupus nephritis".

Pediatr Nephrol 2017 01 13;32(1):191-192. Epub 2016 Oct 13.

Division of Nephrology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, 1873 King Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand.

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http://link.springer.com/10.1007/s00467-016-3508-0
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http://dx.doi.org/10.1007/s00467-016-3508-0DOI Listing
January 2017
3 Reads

Serum Cytokines Th1, Th2, and Th17 Expression Profiling in Active Lupus Nephritis-IV: From a Southern Chinese Han Population.

Mediators Inflamm 2016 22;2016:4927530. Epub 2016 Sep 22.

Department of Nephrology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China; Department of Nephrology, The First Hospital of Xiamen, Fujian Medical University, Xiamen, China.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by aberrant T cell immune response. Diffuse proliferative lupus nephritis (LN-IV) is the most common, severe, and active form of lupus nephritis. In this study, we investigated the production of Th1, Th2, and Th17 cytokines in prediction of active form of LN-IV. Read More

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http://dx.doi.org/10.1155/2016/4927530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055982PMC
June 2017
12 Reads

Mammary-type myofibroblastoma with the nephrotic syndrome.

Proc (Bayl Univ Med Cent) 2016 Jul;29(3):318-20

Division of Nephrology, Department of Internal Medicine (Colbert), Department of Pathology (Kuperman), and Department of Hematology and Oncology (Mennel), Baylor University Medical Center at Dallas; and Texas A&M College of Medicine (Vankawala).

We describe a 23-year-old white man who presented with anasarca and a new periumbilical mass. He had preserved kidney function and laboratory findings consistent with nephrotic syndrome, including 9.7 g/day albuminuria. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900783PMC
July 2016
33 Reads

Histopathological types in adult nephrotic syndrome.

Saudi J Kidney Dis Transpl 2016 May;27(3):576-80

Department of Medicine, Rangpur Medical College, Rangpur, Bangladesh.

In Bangladesh, there are very few studies about biopsy proven adult Nephrotic syndrome (NS) with histological types and their clinical findings. To determine the histological types of glomerulonephritis (GN) in adult NS and correlate them with the clinical presentations and biochemical parameters, we studied 100 biopsies in 87 patients who underwent ultrasonography- guided renal biopsy in Rangpur Medical College and Hospital from July 2010 to June 2012. The mean age of the patients was 32. Read More

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http://dx.doi.org/10.4103/1319-2442.182403DOI Listing
May 2016
10 Reads

Unmasking of complements using proteinase-K in formalin fixed paraffin embedded renal biopsies.

Indian J Nephrol 2016 May-Jun;26(3):182-7

Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Renal biopsy interpretation requires histopathology, direct immunofluorescence (DIF) and electron microscopy. Formalin-fixed, paraffin-embedded tissue (FFPE) sent for light microscopy can be used for DIF after antigen retrieval. However, complement staining has not been satisfactory. Read More

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http://dx.doi.org/10.4103/0971-4065.159558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862263PMC
May 2016
4 Reads

Systemic lupus erythematosus and renal tubular acidosis associated with hyperthyroidism. Case Report.

Neuro Endocrinol Lett 2016 Jul;37(3):169-173

Department of Endocrinology, Institute of Endocrinology and Metabolism, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

A case of a 42-year-old female with hyperthyroidism was subsequently diagnosed to have systemic lupus erythematosus with distal RTA. The clinical examination on admission showed swelling of the knee joints and the urinalysis showed pH 6.5, pro 3+. Read More

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July 2016
9 Reads

Severe acute kidney injury in children owing to infective endocarditis-associated immune complex glomerulonephritis: a report of two cases.

Paediatr Int Child Health 2017 May 29;37(2):144-147. Epub 2016 Jan 29.

c Pathology , Jawaharlal Institute of Postgraduate Medical Education and Research , Pondicherry , India.

Renal involvement in infective endocarditis (IE) may manifest with different clinical patterns, including diffuse proliferative glomerulonephritis and crescentic glomerulonephritis, which may lead to haematuria and/or proteinuria. However, severe acute kidney injury (AKI) in such cases is extremely uncommon and is reported mostly in adults. Two children with rheumatic heart disease and a peri-membranous ventricular septal defect, respectively, who developed haematuria, proteinuria and severe AKI in association with IE are reported. Read More

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http://dx.doi.org/10.1080/20469047.2015.1135562DOI Listing
May 2017
18 Reads
0.871 Impact Factor

Parvovirus B19 induced lupus-like syndrome with nephritis.

Acta Clin Belg 2016 Dec 5;71(6):423-425. Epub 2016 Feb 5.

b Nephrology Department , CSL Vivalia , Arlon , Belgium.

We report a case of a 65-year-old man who developed an acute illness with fever, arthralgia and nephritic syndrome. Antinuclear antibodies were slightly positive and complement levels were low. Renal biopsy showed exudative diffuse proliferative endocapillary glomerulonephritis with diffuse immunoglobulin (IgG, IgA, IgM) and complement deposition (C3d, C4d, C1q) on immunofluorescence. Read More

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http://dx.doi.org/10.1080/17843286.2015.1111673DOI Listing
December 2016
25 Reads

Analysis of clinical presentation, pathological spectra, treatment and outcomes of biopsy-proven acute postinfectious glomerulonephritis in adult indigenous people of the Northern Territory of Australia.

Nephrology (Carlton) 2017 May;22(5):403-411

Department of Nephrology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Aim: Acute postinfectious glomerulonephritis is common in indigenous communities in the Northern Territory, Australia. It is a major risk factor for the high prevalence of chronic kidney disease. We aimed to analyse the clinical presentation, pathological spectra, treatment and outcomes of biopsy-proven acute postinfectious glomerulonephritis in the Northern Territory. Read More

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http://dx.doi.org/10.1111/nep.12797DOI Listing
May 2017
15 Reads

Case Report: Acute Cerebellar Thrombosis in an Adult Patient with IgM Nephropathy.

Methodist Debakey Cardiovasc J 2015 Oct-Dec;11(4):247-9

Houston Methodist Hospital, Houston, Texas.

IgM nephropathy is a relatively rare cause of idiopathic nephrotic syndrome.1 It was initially described by van de Putte,2 then by Cohen and Bhasin in 1978, as a distinctive feature of mesangial proliferative glomerulonephritis.2 It is typically characterized by diffuse IgM deposits on the glomeruli and diffuse mesangial hypercellularity. Read More

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http://journal.houstonmethodist.org/doi/10.14797/mdcj-11-4-2
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http://dx.doi.org/10.14797/mdcj-11-4-247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814013PMC
December 2016
43 Reads

The clinicopathologic characteristics and outcome of atypical anti-glomerular basement membrane nephritis.

Kidney Int 2016 Apr;89(4):897-908

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:

Classic anti-glomerular basement membrane (GBM) disease presents with rapidly progressive glomerulonephritis (GN) with or without pulmonary hemorrhage. On biopsy typical disease displays bright polytypic linear GBM staining for IgG by immunofluorescence and diffuse crescentic/necrotizing GN on light microscopy. Here, we studied 20 patients with atypical anti-GBM nephritis typified by bright linear GBM staining for immunoglobulins but without a diffuse crescentic phenotype. Read More

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http://dx.doi.org/10.1016/j.kint.2016.02.001DOI Listing
April 2016
22 Reads

Diffuse alveolar hemorrhage in IgA nephropathy: case series and systematic review of the literature.

Int J Rheum Dis 2017 Jan 4;20(1):109-121. Epub 2016 Feb 4.

Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Gorimedu, Puducherry, India.

Objectives: To describe the spectrum of pulmonary involvement in immunoglobulin A nephropathy (IgAN).

Methods: We describe two patients with pulmonary renal syndrome related to IgAN and a systematic review of previously reported cases of IgAN and lung involvement.

Results: We identified 23 reports of IgAN-related pulmonary disease, including 19 reports of alveolar hemorrhage and two cases of organizing pneumonia. Read More

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http://dx.doi.org/10.1111/1756-185X.12818DOI Listing
January 2017
8 Reads

Antinuclear Antibody-Negative Lupus Nephritis with Full House Nephropathy: A Case Report and Review of the Literature.

Am J Nephrol 2015 27;42(6):451-9. Epub 2016 Jan 27.

Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA.

Lupus nephritis (LN) is a serious and common complication of systemic lupus erythematosus (SLE) that predisposes to significant morbidity and mortality. Studies show that prompt diagnosis and treatment improves patient survival. We present a case of a 49-year-old female with an atypical presentation of LN who initially presented with new-onset hypertension, edema, arthritis, serositis and recently diagnosed leukocytoclastic vasculitis who later developed acute kidney injury, hematuria and nephrotic syndrome. Read More

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http://dx.doi.org/10.1159/000443747DOI Listing
October 2016
36 Reads

Cryoglobulinemic Glomerulonephritis as a Presentation of Atypical Post-Infectious Glomerulonephritis.

J Clin Med Res 2016 Jan 3;8(1):47-51. Epub 2015 Dec 3.

Department of Nephrology, Staten Island University Hospital, Staten Island, NY, USA.

Post-infectious glomerulonephritis (PIGN) usually occurs within few days to weeks following an infection. Clinical presentation is variable, but in general, it is considered a benign entity with good prognosis. It rarely requires kidney biopsy to confirm the diagnosis. Read More

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http://dx.doi.org/10.14740/jocmr2354wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676346PMC
January 2016
48 Reads

Spotlight on rituximab in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis: current perspectives.

Ther Clin Risk Manag 2015 27;11:1749-58. Epub 2015 Nov 27.

Abteilung für Nephrologie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

A 54-year-old patient presented to his general practitioner because of strong muscle pain in both thighs. Inflammatory parameters (CRP 16.3 mg/dL) and white blood cells (15 g/L) were elevated. Read More

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http://dx.doi.org/10.2147/TCRM.S79080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669915PMC
December 2015
11 Reads

Diffuse mesangial and endocapillary cell proliferative glomerulonephritis with persistent hypocomplementemia in a child.

Int J Clin Exp Med 2015 15;8(9):16834-7. Epub 2015 Sep 15.

Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong University Jinan 250021, P. R. China.

A 15-year-old boy was admitted to People's Hospital of Dong E with anasarca. The laboratory findings revealed proteinuria, hematuria, hypocomplementemia. Renal biopsy specimen revealed diffuse mesangial and endocapillary cell proliferative glomerulonephritis on light microscopic (LM) examination. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659117PMC
December 2015
34 Reads

[Profuse sarcoidosis associated with multiple cutaneous squamous cell carcinomas].

Ann Dermatol Venereol 2015 Dec 24;142(12):751-6. Epub 2015 Oct 24.

Service de dermatologie-vénéréologie, CHU Mohammed VI, 40000 Marrakech, Maroc.

Background: The cutaneous signs of sarcoidosis are polymorphous and occasionally misleading. Herein, we report a rare case of profuse sarcoidosis involving various rare cutaneous signs specific to the disease associated with multiple cutaneous squamous cell carcinomas.

Patients And Methods: A seventy-three-year-old man had been presenting dry ichthyosiform erythroderma for 2 years. Read More

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http://dx.doi.org/10.1016/j.annder.2015.08.012DOI Listing
December 2015
4 Reads

Coexistence of immunoglobulin M nephropathy and autoimmune hemolytic anemia: 2 rare entities.

Iran J Kidney Dis 2015 Nov;9(6):472-4

Department of Nephrology, Ankara Numune Education and Research Hospital, Ankara, Turkey.

Immunoglobulin M (IgM) nephropathy is described as mesengial proliferative glomerulonephritis with diffuse mesengial IgM deposition. We report a patient diagnosed with IgM nephropathy and concomitant autoimmune hemolytic anemia syndrome associated with cold-reacting autoantibodies. Complete remission was achieved with systemic corticosteroid and plasmapheresesis. Read More

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November 2015
10 Reads