Pak J Med Sci 2022 Jan;38(2):417-425
Farhana Amanullah, MBBS, DABP, FAAP. Pediatric Nephrologist, The Indus Hospital and Health Network, and the Aga Khan University Hospital, Karachi, Pakistan.
Rapidly progressive glomerulonephritis (RPGN), characterized by a rapid development of nephritis with loss of kidney function in days or weeks, is typically associated histologically, with crescents in most glomeruli; and is a challenging problem, particularly in low resource settings. RPGN is a diagnostic and therapeutic emergency requiring prompt evaluation and treatment to prevent poor outcomes. Histopathologically, RPGN consists of four major categories, anti-glomerular basement membrane (GBM) disease, immune complex mediated, pauci-immune disorders and idiopathic /overlap disorders. Read More