Clin Neurol Neurosurg 2021 Jun 1;207:106725. Epub 2021 Jun 1.
Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, United States; Department of Neurosurgery, University at Buffalo, Buffalo, NY, United States; Department of Neurosurgery, John R. Oishei Children's Hospital, Buffalo, NY, United States. Electronic address:
Introduction: Currently, there are only 3 reported cases of central nervous system malignancies in patients with Noonan syndrome in the literature, all of which are intracranial pathologies. To our knowledge, there are no cases of spinal cord glioblastoma multiforme reported in the literature.
Case Description: We describe the case of a 12-year-old girl with Noonan syndrome who presented with back pain and new onset neurological deficits and was found to have a spinal cord lesion. Read More