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Br J Ophthalmol 2018 Dec 18. Epub 2018 Dec 18.

Department of Ophthalmology, St Franziskus-Hospital Muenster, Muenster, Germany.

Background/aims: To assess the impact of papillary leakage and active inflammation on optical coherence tomography (OCT)-based retinal nerve fibre layer thickness (RNFLT) and Bruch's membrane opening minimum rim width (BMO-MRW) measurements in uveitic eyes with and without secondary glaucoma.

Methods: Prospective, single-centre analysis of patients with uveitis. All patients included received a fluorescein angiography examination and an OCT scan measuring the BMO-MRW and the RNFLT in three concentric peripapillary ring scans. Read More

Minerva Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Ophthalmology, Harbin Ophthalmology Hospital, Harbin, China.

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):411-418

Department of Ophthalmology, School of Medicine, Kresge Eye Institute, Wayne State University, Detroit, MI, USA.

Purpose: To investigate the frequency of conjunctival erosions in a series of patients who underwent Ahmed valve implantation in a tertiary referral center and to study risk factors associated with the conjunctival erosions.

Methods: This is a single-center, retrospective case-control study of all patients who underwent Ahmed valve implantation between October 2006 and July 2016 at the Kresge Eye Institute in Detroit, Michigan. The series consisted of 306 eyes (277 patients) that underwent Ahmed valve implantation. Read More

F1000Res 2018 22;7:876. Epub 2018 Jun 22.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Tehran, 19839-63113, Iran.

The aim of this study was to compare the safety and efficacy of primary trabeculectomy with mitomycin C and Ahmed glaucoma valve (AGV) implantation in patients with Fuchs heterochromic iridocyclitis (FHIC)-related glaucoma, a rare complication of an uncommon form of uveitis. s In this retrospective comparative case series, 26 FHIC-associated glaucoma patients received trabeculectomy (n=12) or an AGV (n=14). Primary outcome measures were surgical success, defined as intraocular pressure (IOP) ≤21 mmHg, decreasing ≥20% from baseline, and no secondary glaucoma surgery. Read More

J Glaucoma 2019 Jan;28(1):61-67

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

Purpose: To investigate factors associated with decreased corneal endothelial cell density (ECD) after trabeculectomy with mitomycin C (MMC).

Methods: Retrospective review of consecutive glaucoma cases who underwent trabeculectomy with MMC. The types of glaucoma included were primary open-angle glaucoma, exfoliation glaucoma (XFG), neovascular glaucoma, and uveitic glaucoma (UG). Read More

Graefes Arch Clin Exp Ophthalmol 2019 Jan 11;257(1):143-151. Epub 2018 Oct 11.

Department of Ophthalmology, Erasmus Medical Center, 's Gravendijkwal 230, 3000 CA, Rotterdam, The Netherlands.

Purpose: To assess the efficacy of glaucoma drainage devices (GDD) in uveitic glaucoma and non-uveitic glaucoma, and to perform a meta-analysis of previously published results to compare with our data.

Methods: Retrospective case-control study, in which all eyes that underwent GDD surgery were included from 2015 onwards. Cases were defined as patients with uveitic glaucoma. Read More

J Glaucoma 2018 Dec;27(12):1151-1156

Department of Ophthalmology, School of Medicine, Gyeongsang National University Hospital.

Purpose: The main purpose of this study was to evaluate herpesvirus infection in patients with corneal endotheliitis and high intraocular pressure (IOP) using multiplex polymerase chain reaction (PCR) in aqueous humor samples.

Materials And Methods: This was a retrospective, observational study of immunocompetent patients living in South Korea. Eligible subjects had typical corneal endotheliitis with an IOP≥21 mm Hg or required antiglaucoma medication. Read More

Clin Ophthalmol 2018 30;12:1599-1604. Epub 2018 Aug 30.

Department of Ophthalmology, The George Washington University, Washington, DC, USA,

Aim: The aim of this study was to prospectively compare the efficacy, safety, and tolerability of selective laser trabeculoplasty (SLT) vs micropulse laser trabeculoplasty (MLT) in reducing intraocular pressure (IOP) in open-angle glaucoma patients.

Patients And Methods: In all, 38 patients were randomized to 360° MLT and 31 patients were randomized to 360° SLT. IOP was measured at intervals of 1 hour and 1, 1-6, 6-12, 6-24, 24-36, and 36-52 weeks. Read More

Ocul Immunol Inflamm 2018 Sep 13:1-8. Epub 2018 Sep 13.

a Manchester Royal Eye Hospital , Manchester University NHS Foundation Trust , Manchester , UK.

Purpose: This study investigated the efficacy and safety of Baerveldt glaucoma implants (BGI) in adults with uveitic glaucoma (UG) at the Manchester Uveitis Clinic.

Methods: This was a retrospective study of 42 patients with UG who underwent BGI implantation between 2006 and 2015. Primary outcome measures were intraocular pressure (IOP) reduction and number of medications at 5-year follow-up. Read More

Clin Exp Optom 2018 Jul 29. Epub 2018 Jul 29.

US Department of Veterans Affairs, New Jersey Health Care System, East Orange, New Jersey, USA.

Uveitic glaucoma is a range of disorders that results in optic nerve damage from elevated intraocular pressure secondary to intraocular inflammation. As compared to primary open angle glaucoma, uveitic glaucoma is associated with a more aggressive disease course caused by very high intraocular pressure levels that wax and wane. Diagnosis is often based on clinical presentation, disease course, and associated systemic manifestations. Read More

Am J Ophthalmol 2018 Oct 24;194:63-71. Epub 2018 Jul 24.

Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address:

Purpose: Noninfectious uveitis has been treated historically with corticosteroid therapy in varying doses and routes. Triesence, a preservative-free sterile formulation of triamcinolone acetonide, has been used in a wide spectrum of ocular pathologies, but there have been few large studies validating its dosing or detailing long-term side effects in uveitic disease. The primary aim of this study was to describe the relative duration of action and side effects of 2 doses of preservative-free intravitreal triamcinolone acetonide (PF-IVTA) in uveitis. Read More

Arch Soc Esp Oftalmol 2018 Sep 30;93(9):431-438. Epub 2018 Jun 30.

Fundación Oftalmológica Los Andes, Vitacura, Santiago de Chile, España. Electronic address:

Objective: To examine the long-term efficacy, safety and complications of Ahmed glaucoma drainage implant surgery in patients with refractory uveitic glaucoma.

Methods: Retrospective review of consecutive cases of patients with refractory uveitic glaucoma who underwent Ahmed glaucoma drainage implant surgery between 2004-2014. Demographic characteristics of the study population, visual acuity, intraocular pressure (IOP), number of antiglaucoma medications and operative and postoperative complications were recorded. Read More

J Ophthalmic Inflamm Infect 2018 Jun 18;8(1). Epub 2018 Jun 18.

Department of Ophthalmology, USC Roski Eye Institute, Keck Medicine of University of Southern California, 1450 San Pablo Street, Suite 4700, Los Angeles, CA, 90033, USA.

Background: Uveitis is defined as a collection of syndromes involving intraocular inflammation which can lead to pain, tissue damage, and vision loss. Ophthalmic surgery in uveitis patients can be challenging due to inflammation-induced fibrosis and scarring. Trabeculectomy and implantation of glaucoma drainage devices (aqueous shunts) have been used in surgical management of uveitic glaucoma, however there is a paucity of literature examining the comparative results of these entities in this unique setting. Read More

Postgrad Med J 2018 Jul 15;94(1113):417. Epub 2018 Jun 15.

Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Clin Exp Ophthalmol 2018 May;46(4):323-324

Lions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Western Australia, Australia.

J Neurosci Res 2019 Jan 18;97(1):70-76. Epub 2018 May 18.

Department of Ophthalmology, Harvard Medical School, Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts.

Glaucoma is a complex neurodegenerative disease with many clinical subtypes. Some of its rare forms include pigmentary glaucoma, uveitic glaucoma and congenital glaucoma. While they all share common features of progressive retinal ganglion cell (RGC) loss, optic nerve damage and corresponding visual field loss, the exact mechanisms underlying glaucomatous neuron loss are not clear. Read More

Korean J Ophthalmol 2018 06 15;32(3):211-220. Epub 2018 May 15.

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: To evaluate outcomes and factors associated with surgical failure in patients who underwent combined phacoemulsification and Ahmed glaucoma valve (AGV) implantation.

Methods: This retrospective and longitudinal study enrolled 40 eyes (38 patients) that underwent combined phacoemulsification and AGV implantation. Visual acuity, intraocular pressure (IOP), and number of antiglaucoma medications were evaluated preoperatively and postoperatively. Read More

Int Med Case Rep J 2018 1;11:97-103. Epub 2018 May 1.

University Institute for Regenerative Medicine and Oral Implantology (UIRMI), University of the Basque Country, Eduardo Anitua Foundation, Vitoria, Spain.

Purpose: To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) eye drops in patients with glaucoma with secondary ocular surface disorders (OSDs) due to surgeries and topical hypotensive drugs use.

Materials And Methods: A retrospective case-series study design was used including six patients (eight eyes) diagnosed with glaucoma who received surgical (nonpenetrating deep sclerectomy and/or trabeculectomy) and medical treatments (hypotensive eye drops) to control intraocular pressure (IOP) and who developed secondary OSDs, unresponsive to conventional treatments. Patients were treated with PRGF eye drops (four times a day). Read More

Clin Ophthalmol 2018 1;12:799-804. Epub 2018 May 1.

Massachusetts Eye Research and Surgery Institution, Waltham, MA, USA.

Purpose: To evaluate the efficacy and safety of Ahmed glaucoma valve (AGV) in eyes with noninfectious uveitis that had fluocinolone acetonide intravitreal implant (Retisert™)-induced glaucoma.

Methods: This retrospective study reviewed the safety and efficacy of AGV implantation in patients with persistently elevated intraocular pressure (IOP) after implantation of a fluocinolone acetonide intravitreal implant at the Massachusetts Eye Research and Surgery Institution between August 2006 and November 2015.

Results: Nine patients with 10 uveitic eyes were included in this study, none of which had preexisting glaucoma in the study eye. Read More

Klin Monbl Augenheilkd 2018 May 8;235(5):576-585. Epub 2018 May 8.

Augenabteilung am St. Franziskus-Hospital Münster.

An intraocular pressure increase with development of glaucomatous damage is a common complication of uveitis. The prevalence has a wide range depending on various factors such as the underlying uveitis type and the duration of the disease. Pathogenetically, a distinction must be made between a secondary angle closure component and the more frequently occurring open-angle glaucoma. Read More

Int J Ophthalmol 2018 18;11(4):629-634. Epub 2018 Apr 18.

Department of Ophthalmology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230601, Anhui Province, China.

Aim: To report long-term outcomes of secondary glaucoma due to uveitis treated with Ahmed glaucoma valve (AGV) implantation in a series of Chinese patients.

Methods: The retrospective study included 67 eyes from 56 patients with uveitic glaucoma who underwent AGV implantation. Success of the treatment was defined as patients achieving intraocular pressure (IOP) levels between 6 and 21 mm Hg with or without additional anti-glaucoma medications and/or a minimum of 20% reduction from baseline IOP. Read More

Balkan Med J 2018 03;35(2):186-190

Department of Ophthalmology, İstanbul University, Cerrahpaşa School of Medicine, İstanbul, Turkey.

Background: Pediatric cataract surgery differs substantially from adult cataract surgery. Numerous studies have focused on reducing the development of postoperative complications.

Aims: To compare two intraocular lens implantation techniques used in pediatric cataract surgery in terms of postoperative complications. Read More

Graefes Arch Clin Exp Ophthalmol 2018 Apr 21;256(4):809-814. Epub 2018 Feb 21.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.

Purpose: The purpose of this study was to describe the initial experience, efficacy, and safety of ripasudil hydrochloride hydrate (ripasudil), a Rho-associated kinase inhibitor eye drop, for uveitic glaucoma.

Methods: In this retrospective case series, we retrieved the clinical data of 21 eyes from 19 patients with open-angle uveitic glaucoma who were treated with ripasudil at Kobe University Hospital. We analyzed the median intraocular pressure (IOP) reductions after ripasudil treatment and collected the information on the adverse events that were encountered during the course of this treatment period. Read More

Ocul Immunol Inflamm 2018 Feb 2:1-9. Epub 2018 Feb 2.

a Department of Ophthalmology , Postgraduate Institute of Medical Education and Research , Chandigarh , India.

Purpose: To study outcome of secondary glaucoma in pediatric uveitis patients.

Methods: Retrospective analysis of records of uveitis patients ≤16 years.

Results: Of 182 pediatric uveitis patients, secondary glaucoma was seen in 48 patients (75 eyes, 26. Read More

J Glaucoma 2018 Mar;27(3):e61-e63

Department of Ophthalmology, University of California, San Francisco School of Medicine, San Francisco, CA.

Purpose: To report a case of Ahmed glaucoma valve-induced hypotony that was successfully managed with postoperative intraluminal stenting of the aqueous shunt tube.

Patient And Methods: We describe a 68-year-old man with advanced uveitic glaucoma with an intraocular pressure (IOP) of 25 mm Hg in the left eye. The patient initially responded well to an Ahmed glaucoma valve implant, but at 10 weeks postimplantation, the patient underwent cataract surgery and developed persistent hypotony, choroidal folds, and decreased vision. Read More

Ocul Immunol Inflamm 2017 12;25(6):737-739

d Centre for Ophthalmology , University Tuebingen , Tuebingen , Germany.

Am J Ophthalmol Case Rep 2017 Dec 5;8:78-83. Epub 2017 Oct 5.

USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.

Purpose: To report a case of uveitic glaucoma with a congested optic disc where optical coherence tomography angiography (OCT-A) provided diagnostic utility in assessing glaucomatous damage but optical coherence tomography (OCT) alone had limited utility.

Observations: We report a case of a 33-year-old Caucasian female referred to the USC Roski Eye Institute for uncontrolled intraocular pressure (IOP) in the left eye. She was managed by an outside provider for 6 months, where her IOP ranged from 28 to 42 mm Hg in the left eye on maximally tolerated medical therapy. Read More

J Glaucoma 2018 Mar;27(3):e68-e71

Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA.

Purpose: To describe and characterize a novel observation of intraluminal deposits of glaucoma tube shunts (TS) using spectral domain (SD) ocular coherence topography (OCT).

Patients And Methods: Fifteen TS in 11 patients diagnosed with primary open-angle, neovascular, aphakic, and uveitic glaucomas. Both Ahmed (n=11) and Baerveldt (n=4) TS were examined with 5-line raster anterior segment SD-OCT imaging. Read More

Clin Ophthalmol 2017 21;11:2057-2063. Epub 2017 Nov 21.

Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, Thailand.

Objective: The aim of this study was to evaluate the efficacy and safety of preoperative posterior subtenon injection of triamcinolone acetonide (PSTA) in noninfectious uveitic patients with secondary glaucoma undergoing primary trabeculectomy with mitomycin C.

Design: This was a retrospective study.

Patients And Methods: We reviewed the medical records of 10 noninfectious uveitic patients, who had received a single preoperative PSTA 40 mg/1 mL, with secondary glaucoma undergoing primary trabeculectomy with mitomycin C. Read More

Digit J Ophthalmol 2017 11;23(3):63-70. Epub 2017 Sep 11.

Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.

Purpose: To compare the intraocular pressure (IOP) outcomes of Ahmed glaucoma valve (AGV) surgery alone versus AGV with fluocinolone implant in uveitic glaucoma patients.

Methods: We identified uveitic glaucoma patients with AGV surgery alone and AGV surgery combined with fluocinolone implant from the Massachusetts Eye and Ear Ocular Inflammation Database. Demographic information, visual acuity, and IOP were recorded at preoperative visits and 1, 6, and 12 months after surgery. Read More

Eur J Ophthalmol 2018 May 11;28(3):299-305. Epub 2017 Apr 11.

1 Department of Ophthalmology, Campus Virchow Clinic, Charité University Medicine, Berlin - Germany.

Purpose: To assess the correlation between the disc damage likelihood scale (DDLS) objectively measured by a nonmydriatic fundus camera, confocal laser scanning ophthalmoscopy (HRT3), and spectral-domain optical coherence tomography (SD-OCT) in uveitic glaucoma.

Methods: A total of 59 patients with uveitic glaucoma (21 female, 38 male; mean age 56.8 ± 18. Read More

Acta Clin Croat 2016 12;55(4):555-559

Clinical Department of Ophthalmology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

The purpose is to report on the safety and efficacy of Ahmed Glaucoma Valve (AGV, New World Medical, Inc., Rancho Cucamonga, CA, USA) implantation for the management of refractory pediatric glaucoma observed during one-year follow up period. A retrospective chart review was conducted on 10 eyes, all younger than 11 years, with pediatric glaucoma that underwent AGV implantation for medicamentously uncontrolled intraocular pressure (IOP) between 2010 and 2014. Read More

Invest Ophthalmol Vis Sci 2017 10;58(12):5584-5593

Department of Ophthalmology, Graduate School of Medicine, the University of Tokyo, Japan.

Purpose: To investigate the anti-inflammatory properties of ripasudil, a Rho kinase (ROCK) inhibitor, using endotoxin-induced uveitis (EIU) in rats.

Methods: Endotoxin-induced uveitis was induced by footpad injection of lipopolysaccharide (LPS). Ripasudil was administered intraperitoneally 1 hour before and after LPS injection. Read More

Medicine (Baltimore) 2017 Oct;96(43):e7936

aDepartment of Ophthalmology, Eastern Virginia Medical School bVirginia Eye Consultants, Norfolk, VA.

Rationale: Bilateral acute iris transillumination (BAIT) is a poorly-understood ocular syndrome in which patients present with acute iridocyclitis and pigmentary dispersion with or without ocular hypertension. The etiology of the disease remains unknown, though recent reports suggest an antecedent upper respiratory tract infection or systemic antibiotic administration may trigger the clinical syndrome.

Patient Concerns: A 55-year-old female was referred for a second opinion regarding her bilateral ocular pain, photophobia, and ocular hypertension. Read More

Clin Exp Ophthalmol 2018 May 29;46(4):339-345. Epub 2017 Nov 29.

Glaucoma Service, Moorfields Eye Hospital, London, UK.

Importance: The XEN-45 implant, a hydrophilic collagen implant which drains aqueous to the subconjunctival space, has not been investigated in the context of uveitic glaucoma.

Background: To determine the safety and efficacy of the XEN-45 collagen implant in eyes with uveitic glaucoma.

Design: Exploratory prospective case series. Read More

Int Ophthalmol 2018 Dec 14;38(6):2371-2379. Epub 2017 Oct 14.

Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To evaluate the influence of mitomycin C (MMC) concentration on the outcome of trabeculectomy in uveitic glaucoma.

Methods: Retrospective comparative study included 50 patients who underwent MMC-enhanced trabeculectomy for uncontrolled uveitic glaucoma. Patients were divided into two groups based on the concentration of MMC used during trabeculectomy (high [0. Read More

Eur J Ophthalmol 2018 May 9;28(3):294-298. Epub 2017 Nov 9.

6 Department of Ophthalmology, Base Hospital Delhi Cantt and Army College of Medical Sciences, New Delhi - India.

Purpose: To evaluate the outcome of combined Ahmed glaucoma valve (AGV) and phacoemulsification with posterior chamber intraocular lens implantation under infliximab in refractory uveitic glaucoma (UG).

Methods: In this prospective interventional case series, 26 eyes of 26 patients with refractory UG underwent surgery under intravenous infliximab. The success rate was defined as intraocular pressure (IOP) 5 to 21 mm Hg with or without antiglaucoma medications (AGM), without additional glaucoma surgical intervention. Read More

Acta Ophthalmol 2018 Feb 18;96(1):24-30. Epub 2017 Sep 18.

Maastricht University Medical Centre, University Eye Clinic, Maastricht, The Netherlands.

Purpose: To evaluate long-term outcomes on efficacy and safety of severe uveitic glaucoma treated with a Baerveldt glaucoma implant (BGI).

Methods: A retrospective study of 47 eyes of 47 patients with uveitic glaucoma treated by a BGI between September 2002 and September 2015. Main outcome measures were intraocular pressure (IOP), number of glaucoma medications, course of the uveitis, visual acuity (VA) and complications. Read More

Surv Ophthalmol 2018 May - Jun;63(3):347-364. Epub 2017 Sep 5.

Department of Ophthalmology, National and Kapodistrian University of Athens, 1st University Eye Clinic, G. Gennimatas General Hospital, Athens, Greece.

Iris cysts, both primary and secondary, are a diagnostic and treatment challenge. Primary cysts arise either from the iris pigment epithelium or the iris stroma. Posterior pigment epithelial cysts are subdivided according to their location as central, midzonal, and peripheral. Read More

Clin Ophthalmol 2017 22;11:1549-1555. Epub 2017 Aug 22.

Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Purpose: To evaluate the outcome of cataract surgery in adult patients with uveitis.

Materials And Methods: In this retrospective cohort study, medical charts of patients with uveitis and matched control patients without uveitis who underwent cataract surgery at the Eye Clinic, Sahlgrenska University Hospital, Mölndal, between January 2005 and December 2009 were analyzed.

Results: The study included 58 eyes with and 283 eyes without uveitis. Read More

Eye (Lond) 2017 Jul 23;31(7):1008-1019. Epub 2017 Jun 23.

Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Calderdale &Huddersfield NHS Trust, Huddersfield, Yorkshire, UK.

PurposeTo report long-term outcomes of deep sclerectomy (DS) in eyes with raised intraocular pressure (IOP) and glaucoma secondary to uveitis.Patients and methodsRetrospective consecutive case series of 43 eyes of 43 patients with uveitic glaucoma. Mitomycin C (MMC) 0. Read More

Eye (Lond) 2017 Oct 19;31(10):1435-1442. Epub 2017 May 19.

Department of Ophthalmology, Ankara Training and Research Hospital Ankara, Turkey.

PurposeThere is little known about the long-term efficacy and safety of Ahmed glaucoma valve (AGV) implant and about the conditions affecting surgical success in uveitic glaucoma (UG).Patients and methodsThe charts of adult patients with UG who underwent AGV implantation from 2006 to 2015 were reviewed retrospectively.ResultsData of 46 eyes of 39 patients were evaluated. Read More

J Glaucoma 2017 Aug;26(8):747-748

Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA.

Purpose: To report a case of ocular decompression retinopathy that developed in a child after undergoing goniotomy for uncontrolled pediatric uveitic glaucoma.

Patient And Methods: We describe an 11-year-old Hispanic boy with a history of idiopathic uveitis and elevated intraocular pressure (IOP) in both eyes. He developed marked elevation of the IOP in the right eye (44 mm Hg) despite glaucoma medical therapy. Read More

J Glaucoma 2017 Jul;26(7):603-607

*Department of Ophthalmology, University of Tokyo School of Medicine †Department of Ophthalmology, Japan Community Health Care Organization Tokyo Shinjuku Center, Tokyo, Japan.

Purpose: To examine clinical outcomes following an initial trabeculectomy with mitomycin-C for secondary glaucoma associated with uveitis in Behçet disease (BD) patients.

Design: Retrospective interventional case series.

Patients And Methods: Twenty-two eyes in 18 patients with uveitic glaucoma (UG) associated with Behçet disease who underwent an initial trabeculectomy with mitomycin-C between January 1996 and August 2014 were retrospectively reviewed. Read More

BMC Ophthalmol 2017 Mar 21;17(1):30. Epub 2017 Mar 21.

Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, 15213, PA, USA.

Background: To stratify the outcomes of phacoemulsification combined with trabectome surgery using a new glaucoma severity index.

Methods: This is a retrospective, observational cohort study that included open angle glaucoma patients with visually significant cataract that had phacoemulsification combined with trabectome surgery. Exclusion criteria were follow-up less than 12 months, any other surgeries or diagnosis of neovascular or active uveitic glaucoma. Read More

Nippon Ganka Gakkai Zasshi 2017 Mar;121(3):314-34

Glaucoma surgery is classified into a number of areas: intra-ocular drainage, filtration surgery and cyclo-coagulation. Although filtration surgery is the most effective way to lower intraocular pressure (IOP), no surgical technique manages to result in fulfills complete efficacy and safety. Trabeculectomy, one type of filtration surgery, is a common surgical procedure for glaucoma. Read More

J Glaucoma 2017 May;26(5):478-485

*Department of Ophthalmology, College of Medicine ‡Glaucoma Research Chair, King Saud University †Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh §King Abdullah Medical City, Makkah, Saudi Arabia.

Objectives: To evaluate the intermediate and long-term outcomes of mitomycin C-enhanced trabeculectomy as a first glaucoma procedure in uveitic glaucoma.

Materials And Methods: Retrospective cohort study included 70 eyes of 50 patients with uveitic glaucoma who underwent mitomycin C-enhanced trabeculectomy as a first glaucoma procedure at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia between 1996 and 2014. The main outcome measures were: the intraocular pressure (IOP), the number of antiglaucoma medications, the presence of visually threatening complications, and the need for further surgeries to control the IOP. Read More

J Glaucoma 2017 May;26(5):444-449

*Department of Ophthalmology, College of Medicine ‡Glaucoma Research Chair, King Saud University †Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh §King Abdullah Medical City, Makkah, Saudi Arabia.

Objectives: To evaluate the influence of phacoemulsification on intraocular pressure (IOP) control and survival of mitomycin C (MMC)-enhanced trabeculectomy in uveitic glaucoma (UG).

Materials And Methods: Retrospective case-control study included 54 eyes from 40 patients with UG who underwent MMC-enhanced trabeculectomy as an initial procedure to treat glaucoma at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia between 2002 and 2014. Eyes were divided into 2 groups: the first group included eyes that later underwent cataract surgery in the form of phacoemulsification, and the second group included eyes that did not have cataract surgery. Read More

Clin Exp Ophthalmol 2017 Jul 27;45(5):472-480. Epub 2017 Feb 27.

Centre for Eye Research Australia Ophthalmology, University of Melbourne, Department of Surgery, East Melbourne, Victoria, Australia.

Importance: This study provides ophthalmologists who manage uveitic glaucoma with important information on factors that can affect the success of surgical management of this challenging disease.

Background: This study examines surgical outcomes of trabeculectomy and glaucoma device implant (GDI) surgery for uveitic glaucoma, in particular the effect of uveitis activity on surgical outcomes.

Design: Retrospective chart review at a tertiary institution. Read More

Int J Retina Vitreous 2017 23;3. Epub 2017 Jan 23.

Servicio de Retina y Vítreo, Hospital Luis Sánchez Bulnes, Asociación para Evitar la Ceguera en México, I.A.P, Vicente García Torres 46, Colonia Barrio San Lucas, 04030 Coyoacan, Mexico City, Mexico.

Background: Classic retinitis pigmentosa (RP) and other syndromic variants have previously been associated to Fuchs' heterochromic iridocyclitis (FHI). Common immunogenic and inflammatory pathways have been proposed to explain the higher incidence of this uveitic phenomenon in patients with retinal dystrophies without definitive answers. Infrequent variants of RP such as inverse RP have not been previously reported in association with FHI. Read More