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J Glaucoma 2020 Jun 23. Epub 2020 Jun 23.

Wills Eye Hospital, Glaucoma Research Center, Philadelphia, Pennsylvania.

Precis: Baerveldt glaucoma drainage device demonstrated a greater reduction in intraocular pressure than Ahmed in patients with uveitic glaucoma. Most common cause of failure was uncontrolled IOP in Ahmed and hypotony in Baerveldt group.

Purpose: To compare the efficacy and safety of Ahmed and Baerveldt glaucoma drainage devices (GDD) in uveitic glaucoma. Read More

Sci Rep 2020 Jun 25;10(1):10308. Epub 2020 Jun 25.

Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, 860-8556, Japan.

To evaluate the efficacy and safety of ripasudil for treatment of secondary glaucoma, a historical cohort study was conducted at 18 centres in Japan. Adults (age ≥20 years) who needed additional IOP reduction and received topical 0.4% ripasudil between 2014 and 2018 due to three secondary glaucoma subtypes, including uveitic glaucoma (UG), exfoliation glaucoma (EG) or steroid-induced glaucoma (SG) were assessed for mean IOP change from baseline prior to additional treatment with ripasudil. Read More

J Glaucoma 2020 May 26. Epub 2020 May 26.

University Eye Clinic Maastricht, Maastricht University Medical Center, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands.

PRéCIS:: Micropulse TSCPC is an effective and safe IOP-lowering treatment for patients with primary or secondary glaucoma.

Purpose: To investigate the 1- and 2-year effect on intraocular pressure (IOP) and safety profile of micropulse transscleral cyclophotocoagulation in patients with glaucoma.

Methods: Glaucoma patients underwent a standardized micropulse TSCPC (MicroPulse P3 probe, Iridex cyclo G6 laser system, Mountain View, U. Read More

J Glaucoma 2020 May 12. Epub 2020 May 12.

Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.

Precis: In eyes with uveitis and a history of fluocinolone acetonide implantation, glaucoma drainage implants provides excellent long-term control of intraocular pressure.

Purpose: To evaluate the long-term control of intraocular pressure achieved by glaucoma drainage implants (GDI) in uveitic eyes with glaucoma and a fluocinolone acetonide implant (FA; Retisert, Bausch and Lomb, Rochester, NY).

Patients And Methods: Retrospective case series of 56 eyes from 37 patients with a history of non-infectious posterior uveitis who underwent both FA implantation and GDI surgery at the Cleveland Clinic Cole Eye Institute between April 2001 and April 2017. Read More

Br J Ophthalmol 2020 Apr 10. Epub 2020 Apr 10.

Department of Ophthalmology, St. Thomas' Hospital, London, UK

Background: To review the changes in intraocular pressure (IOP) following topical hypotensive medications washout in patients with primary open angle glaucoma (POAG), ocular hypertension (OHT) and uveitic glaucoma (UG)/OHT.

Methods: The study included 120 patients with POAG, OHT and UG recruited from prospective clinical trials between February 2013 and July 2017. We excluded 20 eyes with IOP of ≤21 mm Hg, 11 eyes with previous incisional surgery and 17 eyes with incomplete data. Read More

Br J Ophthalmol 2020 Apr 3. Epub 2020 Apr 3.

Ophthalmology, Greenlane Clinical Centre, Auckland, New Zealand

Aims: To evaluate the long-term risk of permanent vision loss in subjects with anterior uveitis.

Methods: Retrospective study of subjects attending uveitis clinic at Auckland District Health Board and Moorfields Eye Hospital between 2008 and 2018. Main outcome measures were: best corrected visual acuity (BCVA); moderate vision loss (MVL ≤20/50); and severe vision loss (SVL ≤20/200). Read More

BMC Ophthalmol 2020 Feb 27;20(1):76. Epub 2020 Feb 27.

Princess Alexandra Eye Pavilion, Chalmers Street, Edinburgh, EH3 9HA, UK.

Background: The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in Scotland in managing these patients.

Methods: A 7 question electronic survey was distributed to all consultant members of the Scottish Paediatric Club and Scottish Glaucoma Club. Read More

Indian J Ophthalmol 2020 03;68(3):471-474

Department of Glaucoma, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India.

Purpose: To assess the quality and accuracy of glaucoma referrals from ophthalmologist.

Methods: Retrospective review of patients chart with referral letter to a tertiary glaucoma center between January and December 2017. Patients aged <16 years, lens-induced glaucoma, uveitic glaucoma, and glaucoma following retinal and corneal surgery were excluded. Read More

Clin Exp Ophthalmol 2020 Jan;48(1):12-13

Gavin Herbert Eye Institute, University of California, Irvine, California.

J Glaucoma 2020 Apr;29(4):252-257

Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI.

Precis: At 1-year postoperative follow-up, concurrent placement of a dexamethasone intravitreal implant and glaucoma drainage device effectively controlled intraocular pressure (IOP) and inflammation in eyes with uveitic glaucoma with no changes in systemic immunomodulatory therapy.

Purpose: The purpose of this study was to assess 1-year postoperative outcomes in eyes with uncontrolled uveitic glaucoma following concurrent placement of a dexamethasone intravitreal implant and glaucoma drainage device.

Materials And Methods: This is a retrospective, observational case series of patients with chronic, noninfectious uveitis and uveitic glaucoma uncontrolled on maximal tolerated medical therapy with at least 1-year postoperative follow-up. Read More

Medicine (Baltimore) 2020 Jan;99(2):e18652

Department of Ophthalmology, National Defense Medical College, Tokorozawa, Saitama, Japan.

Rationale: Choroidal detachment is a major postoperative complication of trabeculectomy. Postoperative choroidal detachment occurs with low intraocular pressure (IOP), and is naturally resolved by elevation of IOP. We report a case of chronic chorioretinal detachment (CRD) in the eye with uveitic glaucoma after trabeculectomy which persisted with normal IOP resistant for medication and required surgery. Read More

Ocul Immunol Inflamm 2020 Jan 4:1-8. Epub 2020 Jan 4.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

: To compare the safety and efficacy of trans-septal vs. modified posterior sub-Tenon's (PST) corticosteroid injections for noninfectious uveitis.: Retrospective comparison of periocular triamcinolone injection by modified PST (n = 36) vs. Read More

Ocul Immunol Inflamm 2020 Jan 4:1-5. Epub 2020 Jan 4.

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

: To assess the efficacy and safety of high-energy selective laser trabeculoplasty (SLT) for steroid-induced glaucoma in patients with quiescent uveitis.: A retrospective study of steroid-induced glaucoma in quiescent uveitic patients who underwent SLT at our center from December 2014 to November 2017 and had been followed up for at least 1 year. Intraocular pressure (IOP) and IOP-lowering medications were recorded at baseline, and at 1 week, 1 month, 3 months, 6 months and 12 months after SLT. Read More

Surv Ophthalmol 2020 Jul - Aug;65(4):397-407. Epub 2019 Dec 6.

Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Glaucoma secondary to ocular inflammation is potentially blinding and requires aggressive multifaceted management. The pathogenesis is related to the intraocular pressure elevation secondary to compromised aqueous humor outflow by inflammatory cells, chemical mediators released into the aqueous, and to the uveitic therapy itself (corticosteroid induced). The management of uveitic glaucoma needs a careful combination between anti-inflammatory therapy and appropriate intraocular pressure-lowering drugs to prevent worsening of condition and long-term visual loss. Read More

Pediatr Rheumatol Online J 2019 Nov 29;17(1):79. Epub 2019 Nov 29.

Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Background: Refractory non-infectious uveitis is a serious condition that leads to ocular complications and vision loss and requires effective systemic treatment to control disease. The effectiveness of long-term infliximab [IFX] in refractory non-infectious childhood uveitis and the impact of treatment adherence on disease control were evaluated.

Methods: Retrospective, single-center study between December 2002 and April 2016 of 27 children with refractory non-infectious uveitis [17 with juvenile idiopathic arthritis, JIA] treated with long-term IFX [9+ months]. Read More

Turk J Ophthalmol 2019 Oct;49(5):283-293

Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust, United Kingdom

Children comprise a unique population of patients in regard to the diagnostic and therapeutic approach of uveitic glaucoma. The management of glaucoma secondary to uveitis in children is extremely challenging and presents various difficulties, which are associated both with the underlying uveitis and the young age of the patients. The treatment of uveitic glaucoma calls for a thorough and individualized approach, involving both pharmacotherapeutic and surgical modalities. Read More

Ocul Immunol Inflamm 2019 Oct 10:1-7. Epub 2019 Oct 10.

Department of Ophthalmology, St. Franziskus-Hospital Muenster , Muenster , Germany.

Purpose: To evaluate the influence of active inflammation in uveitis on confocal scanning laser tomography (CSLT) and optical coherence tomography (OCT) measurements.

Methods: Prospective enrollment of patients (64 eyes) with non-infectious uveitis. Retinal nerve fiber layer (RNFL), rim-area and -volume for CSLT and Bruch's-membrane-opening minimum-rim-width (BMO-MRW) and retinal nerve fiber layer thickness (RNFL-O) for OCT were recorded. Read More

Clin Exp Ophthalmol 2020 Jan 27;48(1):31-36. Epub 2019 Oct 27.

Doheny Eye Institute and Stein Eye Institute, Department of Ophthalmology, Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.

Importance: To evaluate the safety and efficacy of ab interno trabeculotomy (AIT) (trabecular ablation) with the trabectome in patients with uveitic glaucoma.

Background: Traditional glaucoma filtration surgeries in the uveitic patient population come with a higher risk of complications such as failure and hypotony.

Design: Retrospective observational cohort study. Read More

Am J Ophthalmol 2019 12 30;208:347-355. Epub 2019 Aug 30.

St Thomas Hospital, London, United Kingdom; King's College London, London, United Kingdom. Electronic address:

Purpose: To investigate aqueous humor dynamics in uveitic eyes.

Design: Cross-sectional study.

Participants: Patients with recurrent (≥3 attacks) anterior uveitis (now quiescent) and being treated for glaucoma or ocular hypertension (OHT) (Group 1), previous recurrent anterior uveitis (≥3 attacks) without glaucoma or OHT (Group 2), and normal subjects with no ocular problems and IOP < 21 mm Hg at screening (control group; Group 3). Read More

Ocul Immunol Inflamm 2019 Aug 16:1-6. Epub 2019 Aug 16.

a Department of Ophthalmology, University of Virginia , Charlottesville , VA , USA.

: We performed a meta-analysis to evaluate the effect of uveitis treatment on glaucoma drainage implant surgical outcomes. : We included 16 articles in the meta-analysis. Two groups were defined based on medical therapy of uveitis: Group 1: poorly controlled uveitis, and Group 2: well-controlled uveitis including use of immunomodulatory medications. Read More

J Glaucoma 2019 10;28(10):884-888

Department of Ophthalmology, Gazi University School of Medicine, Ankara.

PRéCIS:: The present study demonstrates that surgical success rate of gonioscopy-assisted transluminal trabeculotomy (GATT) is 83.7% according to target intraocular pressure (IOP) ≤21 mm Hg and ≥20% reduction from baseline in patients with moderate to advanced glaucoma, with an average follow-up of 19.4 months. Read More

Ophthalmol Retina 2019 11 7;3(11):993-997. Epub 2019 Jun 7.

University of California, San Francisco, Department of Ophthalmology, San Francisco, California. Electronic address:

Purpose: To evaluate outcomes in patients with hypotony treated with intravitreal dexamethasone implant (Ozurdex).

Design: Retrospective cohort study.

Participants: Thirteen patients (15 eyes) that received a total of 99 dexamethasone implant injections on occasions at which the intraocular pressure was low, meeting the definition of statistical hypotony. Read More

J Curr Glaucoma Pract 2018 Sep-Dec;12(3):125-138

Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospital, NHS Trust, UK.

Uveitic glaucoma consists one of the most serious complications of intraocular inflammation and, despite its rarity, is considered as one of the leading causes of preventable loss of vision worldwide. It has been associated with a wide spectrum of inflammatory diseases, but its pathogenesis is still not fully comprehended. It appears that the type of inflammation, the steroid-response and the anatomical alterations of the anterior chamber play a pivotal role. Read More

BMC Ophthalmol 2019 Jul 19;19(1):155. Epub 2019 Jul 19.

Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

Background: The object of this study is to investigate the effect of early bleb parameters measured by three-dimensional anterior-segment optical coherence tomography on the surgical success of trabeculectomy.

Methods: This retrospective study included 45 patients with 19 of exfoliation glaucoma, 17 of primary open angle glaucoma, 4 of neovascular glaucoma, 4 of uveitic glaucoma and 1 of glaucoma caused from familial amyloid polyneuropathy who underwent trabeculectomy. Bleb parameters, such as total bleb height, the position and the width of filtration openings on the scleral flap, bleb wall thickness, fluid-filled cavity height, and bleb wall intensity were assessed by three-dimensional anterior-segment optical coherence tomography 0. Read More

Eye (Lond) 2020 Mar 18;34(3):491-498. Epub 2019 Jul 18.

Raghudeep Eye Hospital and Ila Devi Cataract and IOL Research Centre, Ahmedabad, India.

Purpose: To determine the utility of the dexamethasone implant (IVD) as an alternative to systemic steroids as prophylaxis against cystoid macular edema (CMO) in patients with chronic, recurrent CMO associated intermediate or posterior uveitis (IU/PU), and cataract undergoing cataract surgery.

Methods: This was a randomized, parallel design, and clinical trial. Patients with IU/PU and cataract scheduled for cataract surgery were randomly assigned to receive the IVD concurrently with cataract surgery (Group 1: 20 patients) or systemic steroids (Group 2: 23 patients) tapered over 4-6 weeks along with uneventful cataract surgery and routine postoperative care. Read More

Am J Ophthalmol 2019 11 26;207:144-150. Epub 2019 Jun 26.

Optometry and Visual Science, School of Health Sciences, City, University of London, London, United Kingdom. Electronic address:

Purpose: To compare rates of visual field (VF) loss in uveitis patients with glaucoma against patients with primary open-angle glaucoma (POAG) and explore the association between intraocular pressure (IOP) and rate of VF loss.

Design: Retrospective cohort study.

Methods: Anonymized VFs and IOP measurements extracted from the electronic medical records of 5 regionally different glaucoma clinics in England. Read More

Mil Med 2019 12;184(11-12):934-936

Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA.

Minimally invasive glaucoma surgery (MIGS) provides a safe option for individuals with mild to moderate open-angle glaucoma to reduce their need for pharmacologic therapy or more extensive ab externo surgeries. In this report, we describe a surgical technique using both the Kahook Dual Blade and Gonioscopy-assisted transluminal trabeculotomy (GATT), to treat a 23-year-old active duty female with idiopathic uveitis and subsequent corticosteroid-induced glaucoma who presented with consistently elevated intraocular pressure (IOP) measurements despite maximal pharmacologic interventions. This combination was effective in consistently lowering intraocular pressure for at least 12 months in a young, phakic, active duty patient with uveitis and steroid-responsive open-angle glaucoma. Read More

Br J Ophthalmol 2020 Mar 14;104(3):376-380. Epub 2019 Jun 14.

Ophthalmology and Visual Science, Hiroshima University, Hiroshima, Japan.

Aim: To investigate changes in corneal endothelial cell density (CECD) after trabeculectomy.

Methods: This prospective, observational study followed 117 eyes of 117 patients for 2 years after trabeculectomy. The central cornea was examined by corneal specular microscopy prior to and at every 6 months after the surgery. Read More

Clin Rheumatol 2019 Oct 6;38(10):2917-2923. Epub 2019 Jun 6.

Ophthalmology, Department of Surgical, Medical, Molecular Pathology and of Critical Area, University of Pisa, Pisa, Italy.

Introduction: To describe the ocular inflammatory and iatrogenic complications in a cohort of uveitic patients treated in an Italian referral centre.

Material And Methods: Retrospective non-comparative case series. Medical history and clinical findings of all consecutive patients referred to the uveitis center of Pisa University from January 2015 to January 2017 were reviewed. Read More

Klin Monbl Augenheilkd 2019 May 16;236(5):647-652. Epub 2019 May 16.

Augenklinik, Universitätsmedizin Mainz.

Many clinical studies have demonstrated the benefit of topical anti-inflammatory medication before and after glaucoma surgery, especially for trabeculectomy, and that they improve the long term outcome. Pre- and postoperative topical steroids improve the outcome of trabeculectomy, but duration and intensity of treatment should be adapted individually. Systemic steroid or oral immunomodulation have significant impact on the outcome in uveitic glaucoma, but not in other glaucoma subtypes. Read More

J Glaucoma 2019 07;28(7):606-612

Smt Jadhavabai Nathmal Singhvee Glaucoma Services.

Precis: Phacotrabeculectomy with adjunctive mitomycin C is a good option for the management of coexisting cataract and glaucoma. Strict preoperative control of inflammation and close follow-up are essential in the management of eyes with uveitic glaucoma (UG).

Purpose: The purpose of this study was to compare the outcomes of phacotrabeculectomy with adjunctive antimetabolites in the management of patients with UG and patients with primary open-angle glaucoma (POAG). Read More

Int J Ophthalmol 2019 18;12(4):597-602. Epub 2019 Apr 18.

Department of Ophthalmology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.

Aim: To evaluate the safety and the efficacy of the ultrasound ciliary plasty (UCP) on the intraocular pressure (IOP) control in glaucomatous eyes without previous glaucoma surgery.

Methods: A retrospective study included patients with primary and secondary glaucoma who underwent UCP in Dar AlShifa Hospital, Kuwait between January 2017 to June 2018. High-intensity focused ultrasound procedures were performed under peribulbar anesthesia using the 2 generation probe with 8s duration of each of the 6 shots. Read More

Indian J Ophthalmol 2019 Apr;67(4):490-495

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.

Purpose: To evaluate the long-term outcomes of cataract surgery in children with uveitis.

Methods: Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center was done. The main outcome measures were visual acuity and postoperative complications. Read More

Open Med (Wars) 2019 2;14:287-291. Epub 2019 Mar 2.

Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.

Regional anaesthesia techniques in ophthalmology are usually utilized for day case surgery. During various procedures, profound akinesia of the eye and anaesthesia of the surgical site are required, both of which are achieved with retrobulbar block. Due to the anatomy of the eye, life-threatening complications are possible. Read More

Eur J Ophthalmol 2020 Jan 12;30(1):217-220. Epub 2019 Mar 12.

Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

Purpose: Over-filtration and subsequent hypotony are recognised complications of penetrating glaucoma procedures, especially when augmented with antimetabolites. Patients with uveitis are especially at risk of hypotony and this can reduce the final acuity achieved, compromise surgical outcomes and adversely affect the inflammatory status. The incidence of hypotony following XEN45 implant insertion is higher for uveitic patients and we present a method of surgically addressing this hypotony with transconjunctival compression sutures that are placed over the overdraining XEN45 implant. Read More

J Cataract Refract Surg 2019 03;45(3):312-320

Glaukos Corp., San Clemente, California, USA.

Purpose: To assess 5-year outcomes after implantation of 1 trabecular microbypass stent during cataract surgery in eyes with open-angle glaucoma (OAG) or ocular hypertension.

Setting: Private ophthalmology clinic (AaM Augenklinik am Marienplatz, Munich, Germany).

Design: Prospective nonrandomized consecutive case series. Read More

Semin Ophthalmol 2019 21;34(2):93-97. Epub 2019 Feb 21.

b 2nd Department of Ophthalmology , National and Kapodistrian University of Athens , Athens , Greece.

Purpose: The purpose of this review is to summarize current knowledge on XEN implant for the treatment of glaucoma.

Methods: A comprehensive literature review has been performed regarding XEN implant and its use on glaucoma management. Forty-two articles were checked and 37 were found to be relevant. Read More

Br J Ophthalmol 2019 10 18;103(10):1413-1417. Epub 2018 Dec 18.

Department of Ophthalmology, St Franziskus-Hospital Muenster, Muenster, Germany.

Background/aims: To assess the impact of papillary leakage and active inflammation on optical coherence tomography (OCT)-based retinal nerve fibre layer thickness (RNFLT) and Bruch's membrane opening minimum rim width (BMO-MRW) measurements in uveitic eyes with and without secondary glaucoma.

Methods: Prospective, single-centre analysis of patients with uveitis. All patients included received a fluorescein angiography examination and an OCT scan measuring the BMO-MRW and the RNFLT in three concentric peripapillary ring scans. Read More

Minerva Med 2019 Jun 27;110(3):267-269. Epub 2018 Nov 27.

Department of Ophthalmology, Harbin Ophthalmology Hospital, Harbin, China.

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):411-418

Department of Ophthalmology, School of Medicine, Kresge Eye Institute, Wayne State University, Detroit, MI, USA.

Purpose: To investigate the frequency of conjunctival erosions in a series of patients who underwent Ahmed valve implantation in a tertiary referral center and to study risk factors associated with the conjunctival erosions.

Methods: This is a single-center, retrospective case-control study of all patients who underwent Ahmed valve implantation between October 2006 and July 2016 at the Kresge Eye Institute in Detroit, Michigan. The series consisted of 306 eyes (277 patients) that underwent Ahmed valve implantation. Read More

F1000Res 2018 22;7:876. Epub 2018 Jun 22.

Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Tehran, 19839-63113, Iran.

The aim of this study was to compare the safety and efficacy of primary trabeculectomy with mitomycin C and Ahmed glaucoma valve (AGV) implantation in patients with Fuchs heterochromic iridocyclitis (FHIC)-related glaucoma, a rare complication of an uncommon form of uveitis. s In this retrospective comparative case series, 26 FHIC-associated glaucoma patients received trabeculectomy (n=12) or an AGV (n=14). Primary outcome measures were surgical success, defined as intraocular pressure (IOP) ≤21 mmHg, decreasing ≥20% from baseline, and no secondary glaucoma surgery. Read More

J Glaucoma 2019 01;28(1):61-67

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

Purpose: To investigate factors associated with decreased corneal endothelial cell density (ECD) after trabeculectomy with mitomycin C (MMC).

Methods: Retrospective review of consecutive glaucoma cases who underwent trabeculectomy with MMC. The types of glaucoma included were primary open-angle glaucoma, exfoliation glaucoma (XFG), neovascular glaucoma, and uveitic glaucoma (UG). Read More

Graefes Arch Clin Exp Ophthalmol 2019 Jan 11;257(1):143-151. Epub 2018 Oct 11.

Department of Ophthalmology, Erasmus Medical Center, 's Gravendijkwal 230, 3000 CA, Rotterdam, The Netherlands.

Purpose: To assess the efficacy of glaucoma drainage devices (GDD) in uveitic glaucoma and non-uveitic glaucoma, and to perform a meta-analysis of previously published results to compare with our data.

Methods: Retrospective case-control study, in which all eyes that underwent GDD surgery were included from 2015 onwards. Cases were defined as patients with uveitic glaucoma. Read More

J Glaucoma 2018 12;27(12):1151-1156

Department of Ophthalmology, School of Medicine, Gyeongsang National University Hospital.

Purpose: The main purpose of this study was to evaluate herpesvirus infection in patients with corneal endotheliitis and high intraocular pressure (IOP) using multiplex polymerase chain reaction (PCR) in aqueous humor samples.

Materials And Methods: This was a retrospective, observational study of immunocompetent patients living in South Korea. Eligible subjects had typical corneal endotheliitis with an IOP≥21 mm Hg or required antiglaucoma medication. Read More

Clin Ophthalmol 2018 30;12:1599-1604. Epub 2018 Aug 30.

Department of Ophthalmology, The George Washington University, Washington, DC, USA,

Aim: The aim of this study was to prospectively compare the efficacy, safety, and tolerability of selective laser trabeculoplasty (SLT) vs micropulse laser trabeculoplasty (MLT) in reducing intraocular pressure (IOP) in open-angle glaucoma patients.

Patients And Methods: In all, 38 patients were randomized to 360° MLT and 31 patients were randomized to 360° SLT. IOP was measured at intervals of 1 hour and 1, 1-6, 6-12, 6-24, 24-36, and 36-52 weeks. Read More

Ocul Immunol Inflamm 2019 13;27(8):1322-1329. Epub 2018 Sep 13.

Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

This study investigated the efficacy and safety of Baerveldt glaucoma implants (BGI) in adults with uveitic glaucoma (UG) at the Manchester Uveitis Clinic. This was a retrospective study of 42 patients with UG who underwent BGI implantation between 2006 and 2015. Primary outcome measures were intraocular pressure (IOP) reduction and number of medications at 5-year follow-up. Read More

Clin Exp Optom 2019 03 29;102(2):109-115. Epub 2018 Jul 29.

US Department of Veterans Affairs, New Jersey Health Care System, East Orange, New Jersey, USA.

Uveitic glaucoma is a range of disorders that results in optic nerve damage from elevated intraocular pressure secondary to intraocular inflammation. As compared to primary open angle glaucoma, uveitic glaucoma is associated with a more aggressive disease course caused by very high intraocular pressure levels that wax and wane. Diagnosis is often based on clinical presentation, disease course, and associated systemic manifestations. Read More

Am J Ophthalmol 2018 10 24;194:63-71. Epub 2018 Jul 24.

Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address:

Purpose: Noninfectious uveitis has been treated historically with corticosteroid therapy in varying doses and routes. Triesence, a preservative-free sterile formulation of triamcinolone acetonide, has been used in a wide spectrum of ocular pathologies, but there have been few large studies validating its dosing or detailing long-term side effects in uveitic disease. The primary aim of this study was to describe the relative duration of action and side effects of 2 doses of preservative-free intravitreal triamcinolone acetonide (PF-IVTA) in uveitis. Read More

Arch Soc Esp Oftalmol 2018 Sep 30;93(9):431-438. Epub 2018 Jun 30.

Fundación Oftalmológica Los Andes, Vitacura, Santiago de Chile, España. Electronic address:

Objective: To examine the long-term efficacy, safety and complications of Ahmed glaucoma drainage implant surgery in patients with refractory uveitic glaucoma.

Methods: Retrospective review of consecutive cases of patients with refractory uveitic glaucoma who underwent Ahmed glaucoma drainage implant surgery between 2004-2014. Demographic characteristics of the study population, visual acuity, intraocular pressure (IOP), number of antiglaucoma medications and operative and postoperative complications were recorded. Read More

J Ophthalmic Inflamm Infect 2018 Jun 18;8(1). Epub 2018 Jun 18.

Department of Ophthalmology, USC Roski Eye Institute, Keck Medicine of University of Southern California, 1450 San Pablo Street, Suite 4700, Los Angeles, CA, 90033, USA.

Background: Uveitis is defined as a collection of syndromes involving intraocular inflammation which can lead to pain, tissue damage, and vision loss. Ophthalmic surgery in uveitis patients can be challenging due to inflammation-induced fibrosis and scarring. Trabeculectomy and implantation of glaucoma drainage devices (aqueous shunts) have been used in surgical management of uveitic glaucoma, however there is a paucity of literature examining the comparative results of these entities in this unique setting. Read More