1,724 results match your criteria Glaucoma Unilateral

Inter-eye relationship of intraocular pressure change after unilateral trabeculectomy, filtering canaloplasty, or PreserFlo™ microshunt implantation.

Graefes Arch Clin Exp Ophthalmol 2021 May 8. Epub 2021 May 8.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.

Purpose: This study assesses short-term intraocular pressure (IOP) change in the fellow eye of glaucoma patients after mitomycin C-augmented trabeculectomy, filtering canaloplasty, or PreserFlo™ microshunt implantation in the treated eye.

Materials And Methods: Retrospective chart review of 235 glaucoma patients (235 eyes) was performed. Patients underwent initial trabeculectomy (187 patients), filtering canaloplasty (25 patients), or PreserFlo™ microshunt implantation (23 patients) in one eye, while the fellow eye was naïve to any previous glaucoma surgery. Read More

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Ketamine Use in Hysterosalpingography (the Jimah Procedure): A Follow-Up of Bilateral Tubal Evaluation of 27 Infertile  Women  at a Teaching Hospital, Ghana.

Radiol Res Pract 2021 17;2021:6657137. Epub 2021 Apr 17.

Department of Radiology, Korle Bu Teaching Hospital, Accra, Ghana.

Background: Pain, anxiety, and distress are common in radiological investigations including hysterosalpingogram (HSG). Studies suggest that sedation allows patients to better tolerate diagnostic imaging and image-guided procedures by relieving anxiety, discomfort, and pain. This study aimed at assessing the safety and effectiveness of ketamine use in HSG and the proportion of true positive bilateral tubal blockage during HSG using the Jimah Procedure. Read More

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Bag-in-the-lens intraocular lens in paediatric cataract surgery: intraoperative and postoperative outcomes.

Acta Ophthalmol 2021 May 5. Epub 2021 May 5.

Department of Ophthalmology, Haukeland University Hospital, Bergen, Norway.

Purpose: To report intra- and postoperative surgical outcome using the bag-in-the-lens (BIL) technique in paediatric cataract surgery.

Methods: In a retrospective case series, we studied the outcomes of children aged <12 years operated for cataract with the bag-in-the-lens intraocular lens (IOL), with a minimum of 6 months of follow-up.

Results: Since 2013, 50 eyes in 30 patients <12 years (20 bilateral and 10 unilateral) have been operated at our department with the BIL technique, with a median follow-up time of 33. Read More

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Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography.

Int Ophthalmol 2021 May 5. Epub 2021 May 5.

Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.

Purpose: To investigate the changes and evaluate the diagnosis value of circumpapillary vessel density (VD) in cases of acute primary angle closure (APAC).

Design: Case-control study.

Methods: APAC patients with a history of unilateral acute attack were enrolled. Read More

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Unilateral Ocular Siderosis Bulbi Due to Missed Metallic Intraocular Foreign Body Masquerading as Anisocoria of Neurological Origin: A Case Report.

Am J Case Rep 2021 May 5;22:e930504. Epub 2021 May 5.

Department of Special Surgery, Division of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

BACKGROUND Ocular siderosis is an uncommon cause of vision loss due to a retained ferrous intraocular foreign bodies (IOFB) that cause iron deposition in ocular tissues. The most common manifestations are cataract formation, diffuse pigmentary changes of the retinal pigment epithelium, iris heterochromia, dilated pupils, secondary glaucoma, iritis, and cystoid macular edema. CASE REPORT We report a case of 38-year-old man who presented with a left dilated pupil and visual field defect. Read More

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Diagnosis of cytomegalovirus corneal endotheliitis using surgically removed Descemet's membrane and endothelium despite negative results with aqueous humor PCR: a case report.

BMC Ophthalmol 2021 May 1;21(1):194. Epub 2021 May 1.

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.

Background: Cytomegalovirus (CMV) has been known to cause unilateral corneal endotheliitis with keratic precipitates and localized corneal edema, iridocyclitis, and secondary glaucoma. CMV endotheliitis is diagnosed based on clinical manifestations and viral examination using qualitative polymerase chain reaction (PCR) of the aqueous humor.

Case Presentation: An 80-year-old woman was referred to our department for bullous keratopathy. Read More

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Acute interface fluid syndrome after laser in situ keratomileusis in a case of cytomegalovirus (CMV) endotheliitis and secondary glaucoma.

BMJ Case Rep 2021 Apr 30;14(4). Epub 2021 Apr 30.

Jhaveri Microbiology Centre, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Cytomegalovirus (CMV) can cause recalcitrant recurrent keratouveitis and secondary glaucoma. We report a case of chronic recurrent anterior uveitis with secondary glaucoma presenting with acute visual loss and interface fluid 9 years after laser in situ keratomileusis. Based on clinical presentation, a viral aetiology was suspected. Read More

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May ganglion cell complex analysis be a marker for glaucoma susceptibility in unilateral Fuchs' uveitis syndrome?

Graefes Arch Clin Exp Ophthalmol 2021 Apr 30. Epub 2021 Apr 30.

Department of Biostatistics and Medical Informatics, Ege University, Izmir, Turkey.

Purpose: To compare retinal nerve fiber layer (RNFL) thickness and ganglion cell-inner plexiform layer thickness (GCIPLT) in the affected eyes to fellow unaffected eyes of patients with unilateral Fuchs' uveitis syndrome (FUS) and analyze their change over time.

Methods: Twenty seven unilateral FUS patients who did not have concomitant systemic or ocular disease were retrospectively enrolled. Central macular thickness (CMT), RNFL thickness, and GCIPLT measurements were evaluated. Read More

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Circumpapillary optical coherence tomography angiography differences in perimetrically affected and unaffected hemispheres in primary open-angle glaucoma and the preperimetric fellow eye.

Indian J Ophthalmol 2021 May;69(5):1120-1126

Glaucoma Service, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: Evaluation of circumpapillary vessel density (VD) and perfusion density (PD) on optical coherence tomography angiography (OCTa) in mild-moderate glaucoma patients having unilateral visual field defects, with their fellow eyes and controls.

Methods: Both eyes of 24 patients having a definitive nasal step or arcuate scotoma in one hemisphere of one eye only, and 24 controls, underwent OCTa.

Results: In eyes with a superior field defect, the superior/inferior quadrant ratios, (SQ/IQ) of 3 mm scan of VD and PD were significantly higher in eyes with a superior arcuate scotoma than fellow eyes (P = 0. Read More

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Long-term structural and functional outcomes of primary congenital glaucoma.

Graefes Arch Clin Exp Ophthalmol 2021 Apr 22. Epub 2021 Apr 22.

Department of Ophthalmology, National Taiwan University Hospital, No 7, Chung-Shan S. Rd., Taipei, 100, Taiwan.

Purpose: To investigate the clinical characteristics and long-term outcomes of primary congenital glaucoma (PCG) patients.

Methods: In this retrospective, longitudinal, cohort study, PCG patients with reliable visual field (VF) tests and optical coherence tomography (OCT) were included. Disease progression was detected using guided progression analysis with OCT and the change analysis of mean deviation (MD) slope with VF tests. Read More

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Bilateral angle-closure during hospitalization for coronavirus disease-19 (COVID-19): A case report.

Eur J Ophthalmol 2021 Apr 22:11206721211012197. Epub 2021 Apr 22.

Department of Neurosciences, Biomedicine and Movement Sciences, Eye Clinic, University of Verona, Verona, Italy.

Purpose: This report describes a case of bilateral primary angle closure (PAC) progressing to unilateral end-stage primary angle closure glaucoma (PACG) associated with treatment for coronavirus disease-19 (COVID-19) infection.

Methods: A 64-year-old man came to our attention because of blurred vision after a 2-month hospital stay for treatment of COVID-19 infection. Examination findings revealed PACG, with severe visual impairment in the right eye and PAC in the left eye due to plateau iris syndrome. Read More

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Optic Nerve Aplasia.

J Neuroophthalmol 2021 Apr 14. Epub 2021 Apr 14.

Philadelphia College of Osteopathic Medicine (BDS), Philadelphia, Pennsylvania; Pediatric Ophthalmology and Ocular Genetics (BDS, SHY), Wills Eye Hospital, Philadelphia, Pennsylvania; Pediatric Ophthalmology (BEG), Helen DeVos Children's Hospital, Grand Rapids, Michigan; The Rotterdam Eye Hospital (JTHNF), Rotterdam, the Netherlands; Cullen Eye Institute (LSB), Baylor College of Medicine, Houston, Texas; Department of Pediatric Ophthalmology (MB), LV Prasad Eye Institute, Hyderabad, India; Ophthalmology Unit (SG), Ricardo Gutiérrez Children Hospital, Buenos Aires, Argentina; Cataract and Laser Institute of Southern Oregon PC (TR), Medford, Oregon; Flaum Eye Institute and Golisano Children's Hospital (AVL), University of Rochester, New York, New York.

Objective: Optic nerve aplasia (ONA) is a rare ocular anomaly. We report ophthalmologic, systemic, and genetic findings in ONA.

Methods: Patients were identified through an International Pediatric Ophthalmology listserv and from the practice of the senior author. Read More

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Secondary enucleated retinoblastoma with MYCN amplification.

Ophthalmic Genet 2021 Apr 19:1-6. Epub 2021 Apr 19.

Jules-Gonin Eye Hospital, Lausanne University, Lausanne, Switzerland.

: Absence of mutation is rare in retinoblastoma and MYCN amplifications were recently identified in a subset of aggressive retinoblastomas occurring in infants. Here we describe not only the clinical phenotype of MYCN retinoblastoma at presentation, but also the tumor response to the first attempt of conservative management in this context.: Interventional retrospective case report: A 6-month-old boy was referred with right leukocoria. Read More

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Acquired Optic Pits Associated with Laser-assisted Keratomileusis: A Case Series.

J Curr Glaucoma Pract 2020 Sep-Dec;14(3):106-108

Department of Ophthalmology, University of California, Gavin Herbert Eye Institute, Irvine, California, USA; University of California, Irvine School of Medicine, Irvine, California, USA.

Purpose: To present an association between acquired pits of the optic nerve (APON) and prior laser-assisted keratomileusis (LASIK).

Materials And Methods: A retrospective case series of patients with an optic disc pit on clinical exam and a history of LASIK. Spectralis Optical Coherence Tomography images and Humphrey Visual Fields were reviewed from prior visits. Read More

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Clinical outcomes following selective laser trabeculoplasty in Afro-Caribbean patients with glaucoma at high risk for progression.

Br J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Aim: To characterise clinical outcomes following selective laser trabeculoplasty (SLT) in eyes of Afro-Caribbean patients with open-angle glaucoma (OAG) at high risk for progression.

Methods: In a prospective interventional case series, patients meeting high-risk criteria (advanced disease, unilateral glaucoma blindness, inadequate intraocular pressure (IOP) on 2 medications, recent progression on medications, inability to administer, afford or tolerate medications) underwent bilateral 360° SLT and managed based on their subsequent clinical course. Patient-specific indications for SLT-IOP reduction (IOP group) or reduced reliance on medical therapy (MED group)-were recorded before treatment. Read More

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Motion perception and its disorders.

Jason J S Barton

Handb Clin Neurol 2021 ;178:257-275

Departments of Medicine (Neurology), Ophthalmology and Visual Sciences, and Psychology, University of British Columbia, Vancouver, BC, Canada. Electronic address:

As we live in a dynamic world, motion is a fundamental aspect of our visual experience. The advent of computerized stimuli has allowed controlled study of a wide array of motion phenomena, including global integration and segmentation, speed and direction discrimination, motion aftereffects, the optic flow that accompanies self-motion, perception of object form derived from motion cues, and point-light biological motion. Animal studies first revealed the existence of a motion-selective region, the middle temporal (MT) area, also known as V5, located in the lateral occipitotemporal cortex, followed by areas such as V5A (also known as MST, the middle superior temporal area), V6/V6A, the ventral intraparietal area, and others. Read More

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January 2021

Mechanisms implicated in the contralateral effect in the central nervous system after unilateral injury: focus on the visual system.

Neural Regen Res 2021 Nov;16(11):2125-2131

Departamento de Oftalmología, Facultad de Medicina, Universidad de Murcia and Instituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIBArrixaca) Murcia, Spain.

The retina, as part of the central nervous system is an ideal model to study the response of neurons to injury and disease and to test new treatments. During the last decade is becoming clear that unilateral lesions in bilateral areas of the central nervous system trigger an inflammatory response in the contralateral uninjured site. This effect has been better studied in the visual system where, as a rule, one retina is used as experimental and the other as control. Read More

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November 2021

Uveitis-Glaucoma-Hyphema Syndrome: Clinical Features and Differential Diagnosis.

Ocul Immunol Inflamm 2021 Apr 1:1-6. Epub 2021 Apr 1.

Rome Eye Hospital, Rome, Italy.

to study the clinical features of uveitis-glaucoma-hyphema (UGH) syndrome, particularly those useful for a differential diagnosis from unilateral hypertensive acute anterior uveitis. A retrospective chart review was conducted on the clinical features of 9 patients with UGH syndrome. These features were then compared with those detected in 50 patients with unilateral hypertensive acute anterior uveitis. Read More

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Locally Invasive Diffuse Iris Ring Melanoma Presenting as Unilateral Severe Glaucoma: Case Report and Review of Molecular Genetics.

Case Rep Oncol 2021 Jan-Apr;14(1):403-410. Epub 2021 Mar 11.

Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, USA.

We report the clinical history and histopathological findings in a case of diffuse iris ring melanoma (DIM) and review the most recent literature and modern molecular genetics of this entity. An 85-year-old Hispanic man presented with severe unilateral glaucoma, managed at an outside institution for 2 years prior to presentation. Diffuse pigmentation was noted in the angle, on the intraocular lens implant, and in the vitreous without clear demonstration of a mass on ultrasound biomicroscopy. Read More

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Distinguishing Features of Anterior Uveitis Caused by Herpes Simplex Virus, Varicella-Zoster Virus, and Cytomegalovirus.

Am J Ophthalmol 2021 Mar 25;227:191-200. Epub 2021 Mar 25.

Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo (H.T, N.H, M.I, M.M). Electronic address:

Purpose: To determine distinguishing features of the clinical characteristics of anterior uveitis (AU) caused by herpes simplex virus (HSV), varicella-zoster virus (VZV), and cytomegalovirus (CMV).

Design: Retrospective, multicenter case series.

Methods: Consecutive patients with herpetic AU examined at 11 tertiary centers in Japan between January 2012 and December 2017 and who were followed for ≥3 months were evaluated. Read More

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Cesk Slov Oftalmol 2021 ;77(1):28-34

Purpose: The aim of the study was to evaluate ocular surface and tear film in patients with pediatric (primary or secondary) unilateral glaucoma and compare results obtained from the treated eye and untreated healthy eye.

Methods: Patients with unilateral pediatric glaucoma, followed in the outpatient department of the Department of Ophthalmology, Motol University Hospital, were included in this study. Tear osmolarity, corneal epithelial thickness, lower tear meniscus area, Schirmer test, corneal fluorescein staining and tear break-up time test (TBUT) were evaluated in both healthy and treated eye. Read More

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A prospective multicentre study of intravitreal injections and ocular surface in 219 patients: IVIS study.

Acta Ophthalmol 2021 Mar 18. Epub 2021 Mar 18.

Department of Ophthalmology, Desgenettes Military Hospital, Lyon, France.

Purpose: To assess the impact of intravitreal injections (IVTI) on ocular surface of patients treated with multiple injections.

Methods: Prospective, tricentric study conducted in patients treated with unilateral IVTI. An asepsis protocol with povidone-iodine was used for all patients during IVTI. Read More

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Advisability of primary intraocular lens implantation for infants under 2: A systematic review and meta-analysis.

Int J Clin Pract 2021 Mar 16:e14143. Epub 2021 Mar 16.

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital of Capital Medical University, Beijing, China.

Purposes: The present meta-analysis compared the postoperative visual performance of primary intraocular lens (IOL) implantation and primary aphakia in cataract infants.

Methods: PubMed, Embase, Science Direct and Cochrane Library were searched, and postoperative visual acuity (VA) and complications were extracted and pooled.

Results: Three randomised controlled trails (RCTs) and five retrospective studies were included. Read More

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[Sub-foveal choroidal thickness in both eyes of patients with unilateral primary open-angle glaucoma and related influencing factors].

Zhonghua Yan Ke Za Zhi 2021 Mar;57(3):194-200

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.

To investigate and compare the sub-foveal choroidal thickness (SFCT) in both eyes of patients with unilateral primary open-angle glaucoma (POAG) and healthy controls. Cross-sectional study. Patients with unilateral POAG and healthy controls were recruited from September 2018 to September 2019 in the Beijing Tongren Hospital. Read More

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The Relationship Between Corneal Biomechanics and Intraocular Pressure Dynamics in Patients Undergoing Intravitreal Injection.

J Glaucoma 2021 05;30(5):451-458

Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY.

Precis: A higher "corneal resistance factor" (CRF) was associated with greater intraocular pressure (IOP) elevation after intravitreal injection of bevacizumab. Both higher "corneal hysteresis" (CH) and CRF were associated with more rapid IOP recovery postinjection.

Purpose: The purpose of this study was to evaluate the relationship between measurable corneal biomechanical properties and acute IOP elevation after rapid intraocular volume expansion from the routine intravitreal injection. Read More

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Intereye Comparison of the Characteristics of the Peripapillary Choroid in Patients with Unilateral Normal-Tension Glaucoma.

Ophthalmol Glaucoma 2021 Mar 3. Epub 2021 Mar 3.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. Electronic address:

Purpose: To compare the characteristics of the peripapillary choroid (PPC) between the 2 eyes of patients with unilateral treatment-naïve normal-tension glaucoma (NTG).

Design: Observational case series.

Participants: Sixty-nine patients (138 eyes) with treatment-naïve unilateral NTG. Read More

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Comparing Healthcare Resource Utilization and Costs for Patients with Normal Tension Glaucoma Across Levels of Severity: A Retrospective Cohort Study.

Clin Ophthalmol 2021 9;15:453-460. Epub 2021 Feb 9.

The Comparative Health Outcomes, Policy and Economics (CHOICE) Institute, University of Washington, Seattle, WA, USA.

Purpose: To estimate the healthcare resource utilization (HCRU) and costs for patients with normal tension glaucoma (NTG) as well as their payers across various levels of disease severity.

Patients And Methods: Our study was a retrospective cohort study of 6330 US NTG patients. Patients were enrolled if they were 40 years or older and had two or more qualifying NTG diagnoses within the enrollment period, October 1st, 2015 to December 31st, 2017. Read More

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February 2021

Adult presentation of retinoblastoma in Saudi patient.

Saudi J Ophthalmol 2020 Apr-Jun;34(2):136-138. Epub 2020 Dec 28.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

To describe an unusual case of retinoblastoma in adult Saudi. A 21-year-old Saudi male developed acute unilateral visual loss due to a large intraocular lesion in his left eye. Within five days of presentation, the tumor enlarged rapidly causing angle closure glaucoma and orbital cellulitis like picture. Read More

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December 2020

Long-term treatment outcomes for congenital ectropion uveae with ptosis and glaucoma.

J AAPOS 2020 12 24;24(6):369-371. Epub 2020 Oct 24.

Department of Ophthalmology, Singapore National Eye Centre, Singapore. Electronic address:

We describe 3 cases of unilateral congenital ectropion uveae associated with ptosis and glaucoma in a syndrome with no systemic associations. Early detection of glaucoma and timely surgical intervention is required to preserve productive vision in such patients. In our case series, trabeculectomy with mitomycin C was effective in controlling glaucoma progression over a follow-up period of 5-15 years. Read More

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December 2020

Retinoblastoma in an older Hispanic child masquerading as pars planitis: A case report.

Eur J Ophthalmol 2021 Feb 10:1120672121994487. Epub 2021 Feb 10.

Ocular Oncology Service, Institute of Ophthalmology and Visual Sciences, Tecnologico de Monterrey, Monterrey, Mexico.

Introduction: To report a case of a Hispanic girl with late-onset Retinoblastoma (Rb) who was misdiagnosed as a pars planitis prior to referral. Nearly 95% of all Rb cases are detected before age 5, and this patient was 8 years-old.

Methods: Case report of a late-onset Retinoblastoma with anterior chamber (AC) involvement plus the presence of an Ahmed valve. Read More

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February 2021