1,529 results match your criteria Glaucoma Unilateral


Clinical Manifestations, Prognosis And Vaccination Status Of Patients With Rubella Virus-Associated Uveitis.

Am J Ophthalmol 2019 Feb 13. Epub 2019 Feb 13.

Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Purpose: To assess the clinical and laboratory manifestations and vaccination status of uveitis patients positive for Rubella virus (RV) in aqueous humor and investigate its relationship to Fuchs Uveitis Syndrome (FUS).

Methods: Retrospective study of all uveitis patients, positive for RV in aqueous humor analysis (polymerase chain reaction (PCR) and/or Goldmann-Witmer coefficient (GWC)) between January 2010 and October 2016 at the ophthalmology departments in the Erasmus Medical Center (Rotterdam) and University Medical Center Utrecht. Outcomes of aqueous analyses of FUS patients during this period were assessed. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.02.002DOI Listing
February 2019

[Prophylaxis of Recurrent Cytomegalovirus Uveitis with Topical Ganciclovir].

Klin Monbl Augenheilkd 2019 Feb 14. Epub 2019 Feb 14.

Augenklinik, UniversitätsSpital Zürich, Universität Zürich, Schweiz.

Purpose: Cytomegalovirus (CMV) can cause recurrent or chronic hypertensive anterior uveitis in immunocompetent patients. Antiviral treatment options include topical ganciclovir or systemic valganciclovir. However, recurrences are common after stopping treatment. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0816-5598
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http://dx.doi.org/10.1055/a-0816-5598DOI Listing
February 2019
2 Reads

Evaluation of the retinal nerve fiber layer and ganglion cell complex thicknesses in patients with exfoliation syndrome

Turk J Med Sci 2019 Feb 11;49(1):272-278. Epub 2019 Feb 11.

Background/aim: This study aimed to evaluate retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses using spectral domain optical coherence tomography (SD-OCT) in both unilateral and bilateral exfoliation syndrome (XFS) patients

Materials And Methods: Twenty-four patients with unilateral XFS, 20 patients with bilateral XFS, and 23 healthy subjects were enrolled in this study. Eyes with XFS were compared with both fellow eyes and age-matched control subject eyes in terms of mean and segmental RNFL thickness and minimum, mean, and segmental GCC thickness.

Results: In the bilateral XFS group, minimum GCC of the right eye (75. Read More

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http://dx.doi.org/10.3906/sag-1803-27DOI Listing
February 2019

Long-term outcome of phacoemulsification in raptors-A retrospective study (1999-2014).

Vet Ophthalmol 2019 Feb 6. Epub 2019 Feb 6.

Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee.

Objective: To determine long-term outcome of phacoemulsification in raptors at the University of Tennessee Veterinary Medical Center.

Animals Studied: Seven nonreleasable diurnal raptors including, four bald eagles (Haliaeetus leucocephalus), two red-tailed hawks (Buteo jamaicensis), and one peregrine falcon (Falco peregrinus) that had undergone phacoemulsification. All birds showed behavioral changes attributable to visual deficits prior to surgery. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/vop.12624
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http://dx.doi.org/10.1111/vop.12624DOI Listing
February 2019
1 Read

Changes in Optic Nerve Head Vessel Density After Acute Primary Angle Closure Episode.

Invest Ophthalmol Vis Sci 2019 Feb;60(2):552-558

Hamilton Glaucoma Center, Shiley Eye Institute, The Viterbi Family Department of Ophthalmology, University of California San Diego, San Diego, California, United States.

Purpose: To evaluate the changes in circumpapillary vessel density (cpVD) and retinal nerve fiber layer (RNFL) thickness after an acute primary angle closure (APAC) episode.

Methods: Twenty-eight patients (28 pair of eyes) with unilateral APAC and 39 normal subjects (64 eyes) were included in this prospective, observational study. cpVD as measured by optical coherence tomography angiography and RNFL thickness as measured by spectral-domain optical coherence tomography were compared at 6 weeks after an APAC episode between affected, unaffected, and normal eyes. Read More

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.18-25915DOI Listing
February 2019
7 Reads

Optical coherence tomography is highly sensitive in detecting prior optic neuritis.

Neurology 2019 Feb 23;92(6):e527-e535. Epub 2019 Jan 23.

From the Departments of Ophthalmology (S.C.X., J.A.L., J.J.C.) and Neurology (E.P.F., S.J.P., J.J.C.), Mayo Clinic, Rochester, MN; and Department of Ophthalmology (R.H.K.), University of Iowa, Iowa City.

Objective: To explore sensitivity of optical coherence tomography (OCT) in detecting prior unilateral optic neuritis.

Methods: This is a retrospective, observational clinical study of all patients who presented from January 1, 2014, to January 6, 2017, with unilateral optic neuritis and OCT available at least 3 months after the attack. We compared OCT retinal nerve fiber layer (RNFL) and ganglion cell inner plexiform layer (GCIPL) thicknesses between affected and unaffected contralateral eyes. Read More

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http://dx.doi.org/10.1212/WNL.0000000000006873DOI Listing
February 2019

Postoperative Acute Angle-Closure Glaucoma: A Rare but Serious Complication: A Case Report.

A A Pract 2019 Jan 4. Epub 2019 Jan 4.

From the Departments of Anesthesiology, Pain Medicine and Procedural Sedation and Analgesia and.

Acute angle-closure glaucoma is a rare complication of general anesthesia. If not treated in time, acute angle-closure glaucoma can potentially cause permanent loss of vision. Physicians should therefore be vigilant for the possibility of acute angle-closure glaucoma in patients who experience postoperative change or loss of vision. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000935DOI Listing
January 2019
1 Read

[Congenital glaucoma: Intraocular pressure and visual prognosis after trabeculectomy and functional rehabilitation for amblyopia].

J Fr Ophtalmol 2019 Jan 28;42(1):57-62. Epub 2018 Dec 28.

Service d'ophtalmologie, CHU Mohamed VI, avenue Ibn Sina, BP2360 Principal, Marrakech, Maroc.

The goal of our work is to analyze the clinical aspects, study the change in intraocular pressure and functional prognosis after trabeculectomy and amblyopia treatment of children followed for congenital glaucoma. The present study is a retrospective study including 86 patients (143 eyes) followed over a period from March 2009 to September 2015. The median age at diagnosis was 6 months. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.02.028DOI Listing
January 2019

The relationship between optic nerve head deformation and visual field defects in myopic eyes with primary open-angle glaucoma.

PLoS One 2018 31;13(12):e0209755. Epub 2018 Dec 31.

Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan.

Purpose: To investigate the relationship between the morphologic features of myopic optic nerve head (ONH) and visual field (VF) defects in myopic subjects with primary open-angle glaucoma (POAG) by intraindividual comparison.

Methods: Myopic POAG subjects with unilateral glaucomatous VF defect were recruited. The morphologic features of myopic ONH, including optic disc tilt, optic disc rotation, and β-zone parapapillary atrophy (PPA) were measured from color fundus photographs. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209755PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312218PMC
December 2018

Diffuse Unilateral Subacute Neuroretinitis (DUSN).

Adv Exp Med Biol 2018 ;1085:239-241

Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.

Diffuse unilateral subacute neuroretinitis (DUSN) is caused by a subretinal live and mobile nematode. Acute phase: Patients usually present with severe pain, decreased vision, vitritis/papillitis, and tracks of grayish-white lesions-and a live nematode. Late phase: Arterial narrowing, optic atrophy, diffuse disruption of the retinal pigment epithelium (RPE), with severe visual loss. Read More

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http://link.springer.com/10.1007/978-3-319-95046-4_50
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http://dx.doi.org/10.1007/978-3-319-95046-4_50DOI Listing
January 2018
9 Reads

Acute Zonal Occult Outer Retinopathy (AZOOR) and Related Diseases.

Adv Exp Med Biol 2018 ;1085:233-237

Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.

Acute zonal occult outer retinopathy (AZOOR) is a presumed inflammatory disorder with outer retinal dysfunction. Typically, the onset is acute and it is unilateral, with symptoms of photopsias and nasal field loss; scotoma is usually contiguous with the optic nerve. Later, the other eye is involved in nearly three fourths of patients. Read More

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http://link.springer.com/10.1007/978-3-319-95046-4_49
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http://dx.doi.org/10.1007/978-3-319-95046-4_49DOI Listing
January 2018
21 Reads

Glaucoma secondary to intraocular tumors: mechanisms and management.

Curr Opin Ophthalmol 2019 Mar;30(2):71-81

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.

Purpose Of Review: Glaucoma secondary to intraocular tumors is important to consider in eyes with a known tumor and those with unilateral or refractory glaucoma. The purpose of this review is to discuss the mechanisms and management of intraocular tumors with related secondary glaucoma.

Recent Findings: Several intraocular tumors can lead to glaucoma, including iris melanoma, iris metastasis, iris lymphoma, trabecular meshwork melanoma, choroidal melanoma, choroidal metastasis, retinoblastoma, and medulloepithelioma. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000550DOI Listing
March 2019
7 Reads

The Pulfrich Phenomenon: Practical Implications of the Assessment of Cases and Effectiveness of Treatment.

Neuroophthalmology 2018 Dec 25;42(6):349-355. Epub 2018 Apr 25.

Department of Neuro-ophthalmology, Moorfields Eye Hospital, London, United Kingdom.

The Pulfrich phenomenon, originally described in normal observers, is a treatable disorder of the perception of movement in depth in cases of unilateral or asymmetric optic neuropathy. Treatment is highly bespoke and factors influencing treatment response and failure remain unclear. We assessed 25 adults with suspected Pulfrich phenomenon due to a range of conditions in two tertiary referral centres. Read More

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http://dx.doi.org/10.1080/01658107.2018.1446537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276950PMC
December 2018

Quality of life following surgery for congenital glaucoma: findings of the LVPEI congenital glaucoma registry.

Eye (Lond) 2018 Dec 5. Epub 2018 Dec 5.

Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, Hyderabad, India.

Purpose: To evaluate the health-related quality of life (HRQoL) of children operated for primary congenital glaucoma (PCG) using the Kidscreen-27 questionnaire.

Methods: A total of 121 children (mean age, 11.8 years; SD, 2. Read More

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http://dx.doi.org/10.1038/s41433-018-0293-yDOI Listing
December 2018
2 Reads

Cross-Sectional Imaging Analysis of Epiretinal Membrane Involvement in Unilateral Open-Angle Glaucoma Severity.

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5745-5751

Department of Ophthalmology, Osaka University Graduate School of Medicine, Yamadaoka, Japan.

Purpose: To determine the relevance of epiretinal membranes (ERMs) in primary open-angle glaucoma (POAG) and potential risk for glaucoma severity.

Methods: Sixty eyes of 30 patients with POAG who had a unilateral ERM were analyzed; 60 nonglaucomatous eyes of 30 patients with a unilateral ERM also were recruited in this institutional cross-sectional study. Patients underwent swept-source (SS) optical coherence tomography (OCT) imaging and visual field testing. Read More

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.18-25292DOI Listing
December 2018
9 Reads

Quality of life and visual function in children with glaucoma in Spain.

Arch Soc Esp Oftalmol 2018 Nov 13. Epub 2018 Nov 13.

Unidad de Glaucoma, Servicio de Oftalmología, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, España.

Objective: To evaluate the effect of glaucoma on visual function, as well as quality of life in children and quality of life perceived by caregivers in children up to 16 years of age.

Material And Methods: An observational and prospective study was designed using the questionnaire GQL-15 (Glaucoma Quality of Life) and conducted on children and caregivers. The questionnaire VFQ-25 (Visual Functioning Questionnaire) was conducted on children. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03656691183027
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http://dx.doi.org/10.1016/j.oftal.2018.09.001DOI Listing
November 2018
6 Reads

5-year outcomes after primary intraocular lens implantation in children aged 2 years or younger with congenital or infantile cataract: findings from the IoLunder2 prospective inception cohort study.

Lancet Child Adolesc Health 2018 Dec 31;2(12):863-871. Epub 2018 Oct 31.

Life Course Epidemiology and Biostatistics Section, UCL Great Ormond Street Institute of Child Health, University College London, London, UK; UCL Institute of Ophthalmology, University College London, London, UK; Great Ormond Street Hospital NHS Foundation Trust, London, UK; NIHR Moorfields Eye Hospital Biomedical Research Centre, London, UK; Moorfields Eye Hospital NHS Foundation Trust, London, UK; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, UK. Electronic address:

Background: International initiatives to prevent childhood blindness have highlighted the importance of early, effective intervention for congenital and infantile cataract. In the UK, intraocular lens implantation has been widely adopted by surgeons to treat these conditions. However, evidence about the benefits and risks of this technique in different age groups is limited. Read More

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http://dx.doi.org/10.1016/S2352-4642(18)30317-1DOI Listing
December 2018
1 Read

Macular perfusion velocities in the ocular ischaemic syndrome.

Acta Ophthalmol 2019 Feb 27;97(1):113-117. Epub 2018 Oct 27.

Department of Ophthalmology, Rigshospitalet, Glostrup, Denmark.

Purpose: To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects.

Methods: Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS eyes, seven fellow eyes) and 12 control subjects. Read More

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http://doi.wiley.com/10.1111/aos.13950
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http://dx.doi.org/10.1111/aos.13950DOI Listing
February 2019
13 Reads

[Late and sustained intraocular pressure elevation related to intravitreal anti-VEGF injections: Cases requiring filtering surgery (French translation of the article)].

J Fr Ophtalmol 2018 Nov 19;41(9):789-801. Epub 2018 Oct 19.

Centre hospitalier national d'ophtalmologie des 15-20, 28, rue de Charenton, 75012 Paris, France.

We report cases of delayed, sustained elevated intraocular pressure (IOP) associated with repeated intravitreal anti-VEGF injections (IVI), which ultimately resulted in the need for filtering surgery. Two of the three cases demonstrated severe IOP elevation despite maximal medical treatment following unilateral IVI and required urgent filtering surgery. Optic nerve involvement was severe in all three cases. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.03.014DOI Listing
November 2018

Factors associated with early and late failure after goniotomy for primary pediatric glaucoma.

Eur J Ophthalmol 2018 Oct 10:1120672118805872. Epub 2018 Oct 10.

Faculty of Medicine, Cairo University, Cairo, Egypt.

Purpose: To analyze the risk factors associated with early and late failure after goniotomy for primary pediatric glaucoma.

Methods: A retrospective study was done on infants who underwent goniotomy as the initial surgical procedure for primary pediatric glaucoma, and had a follow-up period ⩾48 months after surgery. Early and late failures were defined as intraocular pressure ⩾18 mmHg or signs of glaucoma progression before and after the end of first year, respectively. Read More

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http://dx.doi.org/10.1177/1120672118805872DOI Listing
October 2018
1 Read

Panscleritis as an Unusual Complication of Gonioscopy-assisted Transluminal Trabeculotomy.

J Glaucoma 2019 Feb;28(2):e21-e23

Department of Ophthalmology, Gazi University School of Medicine, Ankara, Turkey.

Purpose: The main purpose of this study was to report a case of panscleritis after gonioscopy-assisted transluminal trabeculotomy (GATT).

Methods: We describe the case of a 33-year-old man with a history of unilateral anterior uveitis and glaucoma, who developed panscleritis after GATT surgery.

Results: Uneventful GATT surgery was performed in a glaucomatous left eye. Read More

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http://Insights.ovid.com/crossref?an=00061198-900000000-9831
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http://dx.doi.org/10.1097/IJG.0000000000001100DOI Listing
February 2019
5 Reads

Disc haemorrhages in Polish Caucasian patients with normal tension glaucoma.

Acta Ophthalmol 2019 Feb 3;97(1):68-73. Epub 2018 Oct 3.

Department of Diagnostics and Microsurgery of Glaucoma, Medical University of Lublin, Lublin, Poland.

Aim: The aim of this observational study was to evaluate the epidemiology of disc haemorrhages (DH) in Polish patients with normal tension glaucoma (NTG) and their association with some risk factors.

Material And Methods: The group studied consisted of 274 Caucasian patients with NTG (410 eyes) divided into those with disk haemorrhages (DH+, = 94 eyes in 81 patients) and those without disc haemorrhages (DH-, = 316 eyes in 193 patients). Ophthalmic examinations with visual field (VF) testing were carried out in these patients every 3 months for at least 18 months. Read More

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http://doi.wiley.com/10.1111/aos.13848
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http://dx.doi.org/10.1111/aos.13848DOI Listing
February 2019
11 Reads

Congenital Corneal Opacities Associated With Trisomy 8 Mosaicism Syndrome.

Cornea 2018 Dec;37(12):1596-1600

Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.

Purpose: To describe the clinical, anterior segment optical coherence tomography (OCT) and histopathological features of 2 infants with congenital corneal opacities (CCOs) and undiagnosed trisomy 8 mosaicism syndrome (T8mS).

Methods: This is a retrospective case report documenting ocular and systemic findings, imaging, pathology and management of 2 patients with T8mS.

Results: An 11-month-old white male infant and a 4-week-old Asian female were initially seen for unilateral and bilateral CCOs, respectively. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001766DOI Listing
December 2018
2 Reads

Melanoma or glaucoma? A case report.

Arch Soc Esp Oftalmol 2018 Dec 27;93(12):610-612. Epub 2018 Sep 27.

Sección de Glaucoma, FISABIO Oftalmología Médica, Valencia, España.

Case Report: The case is presented of a patient referred to us with suspicion of a ciliary body melanoma due to a pigmented lesion in iris root of left eye, associated with high intraocular pressure, despite maximal topical and systemic medication. The systematic workup revealed unilateral changes in the corneal endothelium, compatible with an iridocorneal syndrome. An Ahmed valve was inserted, achieving sustained control of intraocular pressure and visual field defects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03656691183018
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http://dx.doi.org/10.1016/j.oftal.2018.06.002DOI Listing
December 2018
1 Read

Cytomegalovirus-related uncontrolled glaucoma in an immunocompetent patient: a case report and systematic review.

BMC Ophthalmol 2018 Sep 29;18(1):259. Epub 2018 Sep 29.

Department of Ophthalmology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, No. 106, The second zhongshan road, Guangzhou, 510080, Guangdong, China.

Background: Cytomegalovirus can cause ocular anterior uveitis with ocular hypertension. Basis on the therapy, ocular pressure usually can be controlled. We report a case of a man who had unilateral cytomegalovirus anterior uveitis with refractory glaucoma during the process of treatment. Read More

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http://dx.doi.org/10.1186/s12886-018-0917-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162942PMC
September 2018
3 Reads
1.075 Impact Factor

Persistent Fetal Vasculature With Elongated Ciliary Processes in Children.

Am J Ophthalmol 2019 Feb 27;198:25-29. Epub 2018 Sep 27.

Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Electronic address:

Purpose: Outcomes and reoperation rates in infants with unilateral persistent fetal vasculature (PFV) with elongated or stretched ciliary processes have not been extensively studied and were excluded from the Infant Aphakia Treatment Study (IATS). The purpose of this study is to analyze the preoperative measurements, reoperation rates, and complications after surgery in unilateral anterior PFV with stretched processes.

Design: Retrospective case series. Read More

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http://dx.doi.org/10.1016/j.ajo.2018.09.019DOI Listing
February 2019

Ocular Antihypertensive Medication Use After iStent Implantation Concurrent With Cataract Surgery vs Cataract Surgery Alone in a Large US Health Care Claims Database.

JAMA Ophthalmol 2018 Sep 27. Epub 2018 Sep 27.

Byers Eye Institute, Stanford University, Palo Alto, California.

Importance: The iStent Trabecular Micro-Bypass (Glaukos Corporation) is a minimally invasive glaucoma implant used in conjunction with cataract surgery to lower intraocular pressure.

Objective: To determine whether implantation of the iStent concurrent with cataract surgery is associated with reduced use of ocular antihypertensive medications in a US health care claims database.

Design, Setting, And Participants: Retrospective, observational longitudinal cohort study of individuals enrolled in a US managed care network who underwent iStent implantation with cataract surgery (iStent/CEIOL) from 2012 to 2016 (n = 1509 bilateral and n = 1462 unilateral surgery). Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2018.4461DOI Listing
September 2018
1 Read

Preoperative biometry data of eyes with unilateral congenital cataract.

J Cataract Refract Surg 2018 Oct;44(10):1198-1202

From the Department of Ophthalmology, Semmelweis University, Budapest, Hungary.

Purpose: To investigate the differences in biometry data of eyes with unilateral congenital cataract and the contralateral normal eyes in pediatric patients.

Setting: Pediatric Ophthalmology Division, Ophthalmology Department, Semmelweis University in Budapest, Hungary.

Design: Retrospective case series. Read More

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http://dx.doi.org/10.1016/j.jcrs.2018.06.054DOI Listing
October 2018
2 Reads

Lymphatic vessels of the eye - old questions - new insights.

Ann Anat 2019 Jan 18;221:1-16. Epub 2018 Sep 18.

Klinik für Augenheilkunde, Universitätsklinikum Düsseldorf, Heinrich Heine Universität Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.

Due to its accessible position and tissue heterogeneity, the eye is ideally suited for studying the lymphatic system. As early as the 19th century, questions about the origin and function of this system were discussed. For example, whether Schlemm's canal, which is of particular importance in the pathogenesis of glaucoma, is a lymphatic vessel, or does this vascular system begin with finger-shaped protuberances? Despite the discovery of lymphatic endothelial molecules and the use of molecular imaging technologies, these questions are still discussed controversially today. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09409602183011
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http://dx.doi.org/10.1016/j.aanat.2018.08.004DOI Listing
January 2019
5 Reads

Three dimensional neuro-retinal rim thickness and retinal nerve fiber layer thickness using high-definition optical coherence tomography for open-angle glaucoma.

Jpn J Ophthalmol 2018 Nov 18;62(6):634-642. Epub 2018 Sep 18.

Department of Ophthalmology, Seoul National University Hospital, 101, Daehak-Ro Jongno-Gu, Seoul, 03080, Republic of Korea.

Purpose: To compare the diagnostic capability of three-dimensional (3D) neuro-retinal rim thickness (NRR) with existing optic nerve head and retinal nerve fiber layer (RNFL) scan parameters using high-definition optical coherence tomography (HD-OCT).

Design: Retrospective study.

Methods: Based on the mean deviation (MD) of the Humphrey Field Analyzer (HFA), the 152 subjects were categorized into mild (MD > - 6 dB, 100), moderate (MD - 6 to - 12 dB, 26), and severe (MD < - 12 dB, 26) glaucoma. Read More

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http://link.springer.com/10.1007/s10384-018-0620-7
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http://dx.doi.org/10.1007/s10384-018-0620-7DOI Listing
November 2018
4 Reads

Late and sustained intraocular pressure elevation related to intravitreal anti-VEGF injections: Cases requiring filtering surgery.

J Fr Ophtalmol 2018 Oct 7;41(8):e329-e340. Epub 2018 Sep 7.

Centre hospitalier national d'ophtalmologie des 15-20, 28, rue de Charenton, 75012 Paris, France.

We report cases of delayed, sustained elevated intraocular pressure (IOP) associated with repeated intravitreal anti-VEGF injections (IVI), which ultimately resulted in the need for filtering surgery. Two of the three cases demonstrated severe IOP elevation despite maximal medical treatment following unilateral IVI and required urgent filtering surgery. Optic nerve involvement was severe in all three cases. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.07.002DOI Listing
October 2018

A follow-on study on vision-related quality of life assessment using the NEI-VFQ-25 in those with a history of unilateral and bilateral congenital cataracts.

Acta Ophthalmol 2018 Aug;96(5):e596-e599

Temple Street Children's University Hospital, Dublin, Ireland.

Purpose: To assess vision-specific health-related quality of life (using the NEI-VFQ-25), educational attainment and visual acuity (VA) in patients with a history of congenital cataracts and appraise these in relation to Kirwan et al.'s (Pediatr Ophthalmol Strabismus 49, 2012, 26) study.

Methods: A retrospective hospital-based study of patients with unilateral and bilateral congenital cataracts whounderwent surgery aged younger than 12 months. Read More

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http://dx.doi.org/10.1111/aos.13692DOI Listing
August 2018
1 Read

Iris Microhemangiomatosis: Clinical, Fluorescein Angiography, and Optical Coherence Tomography Angiography Features in 14 Consecutive Patients.

Am J Ophthalmol 2018 Dec 15;196:18-25. Epub 2018 Aug 15.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:

Purpose: To describe the clinical and imaging findings and treatment options in a series of patients with iris microhemangiomatosis.

Design: Retrospective observational case series.

Methods: Setting: Single institution. Read More

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http://dx.doi.org/10.1016/j.ajo.2018.08.011DOI Listing
December 2018
1 Read

Concordance of 24-h intraocular pressure curve in patients with untreated unilateral primary open-angle glaucoma.

Exp Ther Med 2018 Aug 15;16(2):1461-1469. Epub 2018 Jun 15.

Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, Shanghai 200025, P.R. China.

The present study aimed to assess the concordance of 24-h intraocular pressure (IOP) curves between glaucomatous and contralateral eyes for patients with untreated unilateral primary open-angle glaucoma (POAG). A total of 32 patients with unilateral POAG and 32 age-matched normal subjects were enrolled. The IOP measurements were performed every 2 h over a 24-h period. Read More

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http://dx.doi.org/10.3892/etm.2018.6315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090307PMC
August 2018
0.941 Impact Factor

Lacrimal Gland Changes on Orbital Imaging after Glaucoma Drainage Implant Surgery.

J Ophthalmic Vis Res 2018 Jul-Sep;13(3):219-223

Department of Ophthalmology, Eye Institute at Harborview, University of Washington Medical Center, Seattle, Washington, USA.

Purpose: This study evaluates the radiographic appearance of lacrimal gland tissue after placement of a glaucoma drainage implant (GDI) to characterize the impact of the device on the gland's imaging patterns.

Methods: We performed retrospective chart review of departmental records at two urban academic medical centers, which were systematically searched using procedure codes to identify adult glaucoma patients who underwent unilateral superotemporal GDI from January 1995 to December 2015. Radiology records were cross-checked to identify the subset of patients who underwent postoperative orbital CT or MRI. Read More

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http://dx.doi.org/10.4103/jovr.jovr_200_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058550PMC
August 2018
1 Read

Incontinentia pigmenti-associated ocular anomalies of paediatric incontinentia pigmenti patients in China.

Acta Ophthalmol 2018 Aug 3. Epub 2018 Aug 3.

Department of Ophthalmology, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Purpose: To characterize ocular manifestations in a cohort of paediatric patients with incontinentia pigmenti (IP) and to define the guidelines for grading of IP-associated retinopathy (IPR).

Methods: This retrospective review was performed on patients under the age of 18 years with a diagnosis of IP. Data included demographics, medical history, ocular examination, and accessory examination. Read More

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http://dx.doi.org/10.1111/aos.13781DOI Listing
August 2018
13 Reads
2.840 Impact Factor

Low Sensitivity of the Van Herick Method for Detecting Gonioscopic Angle Closure Independent of Observer Expertise.

Am J Ophthalmol 2018 Nov 31;195:63-71. Epub 2018 Jul 31.

Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Purpose: To evaluate the diagnostic performance characteristics of the Van Herick assessment (VHA) for identifying angle closure compared to gold-standard gonioscopy, as conducted by trained observers of varying expertise.

Design: Reliability analysis.

Methods: Patients (n = 131) from a glaucoma referral clinic aged ≥50 years without prior ocular surgery or iridotomy underwent unilateral VHA by 1 of 11 trained ophthalmic technicians, followed by VHA and indirect gonioscopy by 1 of 15 ophthalmology residents and 1 of 4 glaucoma specialist attending physicians. Read More

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http://dx.doi.org/10.1016/j.ajo.2018.07.026DOI Listing
November 2018
7 Reads
3.871 Impact Factor

STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS IN A PATIENT WITH MACULAR TELANGIECTASIA TYPE 2.

Retin Cases Brief Rep 2018 Jul 30. Epub 2018 Jul 30.

Department of Ophthalmology, Medical University of Graz, Graz, Austria.

Purpose: To present a case of unilateral stellate nonhereditary idiopathic foveomacular retinoschisis in a patient with macular telangiectasia (MacTel) Type 2.

Methods: Single-patient case report.

Results: A 61-year-old female white patient was referred to our clinic with metamorphopsia and reduction of visual acuity over a period of 2 months on her right eye. Read More

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http://Insights.ovid.com/crossref?an=01271216-900000000-9877
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http://dx.doi.org/10.1097/ICB.0000000000000801DOI Listing
July 2018
2 Reads

Indistinguishable gene expression between healthy eyes and eyes with unilateral exfoliative glaucoma.

Clin Ophthalmol 2018 17;12:1155-1162. Epub 2018 Jul 17.

TATAA Biocenter, Gothenburg, Sweden.

Background: Glaucoma is an optic neuropathy associated with visual field loss. There are different types of glaucoma, among them exfoliative glaucoma. Glaucoma can present as unilateral or bilateral. Read More

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http://dx.doi.org/10.2147/OPTH.S166958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055626PMC

Ocular hypertension in patients with central/hemicentral retinal vein occlusions: cumulative prevalence and management.

Int J Ophthalmol 2018 18;11(7):1173-1178. Epub 2018 Jul 18.

Department of AET Discipline of Descriptive Geometry and Engineering Graphics, Faculty of Mechanical Engineering, Technical University of Cluj-Napoca, Cluj-Napoca 400012, Romania.

Aim: To prospectively evaluate the cumulative prevalence and the management of ocular hypertension (OH) in patients with unilateral acute central/hemicentral retinal vein occlusions (C/HCRVOs) over the course of 3y.

Methods: The study included 57 patients with unilateral acute C/HCRVOs. All patients underwent a comprehensive ophthalmological examination of both eyes. Read More

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http://dx.doi.org/10.18240/ijo.2018.07.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048337PMC

Post-traumatic right carotid-cavernous fistula resulting in symptoms in the contralateral eye: a case report and literature review.

BMC Ophthalmol 2018 Jul 25;18(1):183. Epub 2018 Jul 25.

Department of Ophthalmology, The First Affiliated Hospital, Jinan University, 613 West Huangpu Ave, Guangzhou, 510632, China.

Background: To report a case of a carotid-cavernous fistula (CCF) that occurred after a motor vehicle accident and review the uniqueness of this case and the main confusing points for the diagnosis of such cases.

Case Presentation: A 22-year-old man complained of left eyelid swelling, eye redness, visual decrease and occasional headache after motor vehicle accident 4 months prior during which he experienced a head injury. He was initially thought to have glaucoma, but he was finally diagnosed with a right CCF based on magnetic resonance imaging (MRI) and digital subtraction angiography (DSA). Read More

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http://dx.doi.org/10.1186/s12886-018-0863-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060543PMC
July 2018
1 Read
1.075 Impact Factor

Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months.

Indian J Ophthalmol 2018 08;66(8):1088-1093

Department of Pediatric Ophthalmology, Strabismus, and Neuro-Ophthalmology, Jasti V Ramanamma Children's Eye Care Centre, Child Sight Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age.

Methods: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection criteria who underwent cataract surgery (lens aspiration, primary posterior capsulorhexis, and anterior vitrectomy) with primary IOL implantation between January 2008 and December 2011 and minimum 3-year follow-up were included. Read More

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http://dx.doi.org/10.4103/ijo.IJO_182_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080482PMC
August 2018
2 Reads

Butyrate, a Gut Bacterial Metabolite, Lowers Intraocular Pressure in Normotensive But Not in Hypertensive Rats.

J Glaucoma 2018 Sep;27(9):823-827

Departments of Experimental Physiology and Pathophysiology.

Background: Accumulating evidence supports a role of gut bacterial metabolites in arterial blood pressure (BP) regulation. Since the mechanisms controlling intraocular pressure (IOP) and BP overlap, we hypothesized that butyrate, a bacterial metabolite, might affect both IOP and BP.

Methods: IOP, BP, and heart rate (HR) were measured at baseline and after the intraperitoneal administration of either butyrate or a vehicle (0. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001025DOI Listing
September 2018
5 Reads

Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, on Aqueous Humor Dynamics in Laser-Induced Ocular Hypertensive Monkeys.

J Ocul Pharmacol Ther 2018 Sep 10;34(7):531-537. Epub 2018 Jul 10.

1 R&D Division, Santen Pharmaceutical Co., Ltd. , Nara, Japan .

Purpose: To investigate the mechanism of the intraocular pressure (IOP)-lowering effect of a novel selective prostaglandin E2 receptor 2 (EP2) receptor agonist, omidenepag isopropyl (OMDI).

Methods: The effect of OMDI on IOP and aqueous humor dynamics was evaluated in cynomolgus monkeys with unilateral laser-induced ocular hypertension. In a crossover manner, the hypertensive eye of each monkey was dosed once daily with 20 μL of either 0. Read More

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http://dx.doi.org/10.1089/jop.2017.0146DOI Listing
September 2018
4 Reads

Orbital, eyelid, and nasopharyngeal silicone oil granuloma presenting as ptosis & pseudo-xanthelasma.

Am J Ophthalmol Case Rep 2018 Sep 14;11:45-48. Epub 2018 May 14.

Department of Ophthalmology, Byers Eye Institute at Stanford University, 2452 Watson Court, Palo Alto, CA, United States.

Purpose: To highlight the presentation and management of a patient with eyelid, orbital and nasopharyngeal silicone oil migration through a glaucoma drainage implant presenting as pseudo-xanthelasma and ptosis.

Observations: A 68-year male presented with unilateral ptosis and presumed xanthelasma. He had a history of glaucoma drainage implant surgery, pseudophakia, and multiple retinal detachment repairs with silicone oil. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026769PMC
September 2018
2 Reads

Optical coherence tomography angiography at the acute phase of optic disc edema.

Eye Vis (Lond) 2018 23;5:15. Epub 2018 Jun 23.

1Service d'Ophtalmologie, CHU de Bordeaux, Bordeaux, France.

Background: The differential diagnosis of optic disc edema at the acute phase can be challenging. OCT angiography (OCTA) is a new technology allowing the visualization of the peripapillary vascular network and optic disc capillaries. The peripapillary network alterations of glaucoma and chronic non-arteritic anterior ischemic optic neuropathy (NAION) were reported. Read More

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http://dx.doi.org/10.1186/s40662-018-0109-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015448PMC
June 2018
2 Reads

Early Results of Penetrating Keratoplasty in Patients With Unilateral Chemical Injury After Simple Limbal Epithelial Transplantation.

Cornea 2018 Oct;37(10):1249-1254

Department of Cornea, Refractive Surgery and Ocular Surface Disorders, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.

Purpose: To evaluate clinical outcomes of sequential PKP in eyes with unilateral chemical injury, which have previously undergone autologous simple limbal epithelial transplantation (SLET) at a tertiary eye center in North India.

Methods: This is a single-center, retrospective, noncomparative interventional case series reviewing patients with unilateral limbal stem cell deficiency treated by SLET and sequential PKP between 2012 and 2017. The primary outcome was defined as allograft survival, defined as a completely epithelialized, clear, avascular graft. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001681DOI Listing
October 2018
13 Reads

Different composition of intraocular immune mediators in Posner-Schlossman-Syndrome and Fuchs' Uveitis.

PLoS One 2018 26;13(6):e0199301. Epub 2018 Jun 26.

Department of Ophthalmology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Posner-Schlossman-Syndrome (PSS) is clinically characterized by acute, recurrent, mild, unilateral uveitis anterior accompanied by elevated intraocular pressure (IOP). Fuchs´ Uveitis (FU) is a chronic, low-grade-inflammatory disorder, involving anterior uvea and vitreous. The clinical findings show remarkable similarities as well as differences. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199301PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019249PMC
June 2018
10 Reads
3.234 Impact Factor

Rare Case Of Primary Congenital Glaucoma With Hypoplasia Corpus Callosum.

J Ayub Med Coll Abbottabad 2018 Apr-Jun;30(2):286-288

Division of Neurology, Department of Paediatrics, Surabaya, Indonesia.

Primary congenital glaucoma is a rare disease that causes elevated intraocular pressure within the first three years of life. Few studies have explored the association of primary congenital glaucoma with malformation of corpus callosum. We report on a six-month-old female presenting with unilateral primary congenital glaucoma associated with hypoplasia of corpus callosum in Indonesian infant. Read More

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October 2018
5 Reads

LVP keratoprosthesis: anatomical and functional outcomes in bilateral end-stage corneal blindness.

Br J Ophthalmol 2018 Jun 11. Epub 2018 Jun 11.

Tej Kohli Cornea Institute, LV Prasad Eye Institute, Hyderabad, India.

Purpose: To describe the anatomical and functional outcomes of the novel LVP keratoprosthesis (Kpro), developed as an alternative to the modified osteo-odonto keratoprosthesis (MOOKP), in eyes with end-stage corneal blindness where conventional corneal surgeries are contraindicated.

Methods: This prospective case series included 58 eyes of 56 patients (12 children and 44 adults) with severe bilateral keratopathy and completely dry, dermalised ocular surfaces who underwent unilateral LVP Kpro implantation from 2012 to 2016. In this two-stage procedure, an ocular surface labial mucous membrane grafting was performed, followed for 3 months by the implantation of the device under the engrafted mucosal flap. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2017-311649DOI Listing
June 2018
11 Reads