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N Z Med J 2022 Apr 14;135(1553):35-42. Epub 2022 Apr 14.

MB ChB FRANZCO: Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.

Aim: We aimed to estimate the prevalence of glaucoma in New Zealand using a population-based birth cohort of 45-year-olds.

Methods: Study members of the Dunedin Multidisciplinary Health & Development Study participated (n=938 out of 1037 births (91%)). The data collected included visual acuity, visual field (VF), refraction, central corneal thickness, intraocular pressure (IOP), axial length, spectral domain optical coherence tomography (OCT), and non-mydriatic fundus photographs. Read More

Front Microbiol 2022 2;13:738742. Epub 2022 Jun 2.

Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Human T-cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus identified as the causative agent of human diseases, such as adult T-cell leukemia, HTLV-1-associated myelopathy, and HTLV-1 uveitis (HU). HU is one of the most frequent ocular inflammatory diseases in endemic areas, which has raised considerable public health concerns. Approximately 30% of HU patients develop secondary glaucoma, which is higher than the general uveitis incidence. Read More

Middle East Afr J Ophthalmol 2021 Oct-Dec;28(4):221-225. Epub 2022 Apr 30.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Purpose: Glaucoma is a leading cause of visual impairment worldwide, and plateau iris syndrome (PIS) is the most common nonpupillary block mechanism of angle closure. This study aims to assess the prevalence of PIS among Saudi population.

Methods: It is a prospective observational study that examined patients previously diagnosed with chronic angle closure. Read More

F1000Res 2022 28;11:112. Epub 2022 Jan 28.

Rehabilitation, Clínica Godoy, Sao Jose do Rio Preto, São Paulo, 15020010, Brazil.

The aim of the present study is to report the indirect evaluation of cervical stimulation considering the effect of the duration of the stimulus on the control of intraocular pressure in a patient with bilateral glaucoma with important ocular edema. A 47-year-old woman reported the onset of pain and bilateral tearing in the eyes at 35 years of age and was diagnosed with glaucoma. The patient began clinical treatment, but intraocular pressure remained 35 to 40 mmHg even with the use of four eye medications in the form of drops. Read More

Ethiop J Health Sci 2022 Mar;32(2):463-466

Department of Ophthalmology, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia.

Background: Primary congenital glaucoma is potentially blinding condition characterized by elevated intraocular pressure and optic disc cupping. It is typically bilateral and usually manifest in the first year of life. Spontaneously arrested primary congenital glaucoma can occur, but it is very rare. Read More

Pan Afr Med J 2022 6;42. Epub 2022 May 6.

Centre Hospitalier Régional de Kara, Kara, Togo.

Introduction: the purpose of this study was to evaluate the knowledge, attitudes and practices (KAP) related to cataract and glaucoma in the population of Conakry Guinea.

Methods: we conducted a prospective descriptive and analytical study at the Bartimée Clinic over a period of three months. All patients who agreed to answer our questionnaire and having an age ≥18 years were included. Read More

Clin Ophthalmol 2022 1;16:1707-1719. Epub 2022 Jun 1.

Eye Clinic, Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milano, Italy.

Introduction: The VISIONARY study examined the intraocular pressure (IOP)-lowering efficacy and tolerability of the preservative-free fixed-dose combination of tafluprost (0.0015%) and timolol (0.5%) (PF tafluprost/timolol FC) in a real-world setting. Read More

BMC Ophthalmol 2022 Jun 4;22(1):249. Epub 2022 Jun 4.

Department of Ophthalmology, Second Xiangya Hospital, Central South University, Hunan, 410011, China.

Background: Glaucoma is a group of eye diseases that can damage the optic nerve and cause vision loss. A novel technology micropulse laser trabeculoplasty (MLT) can use duty-circle subvisible laser pulses to treat glaucoma. The aim of this study is to evaluate the efficacy of 360° MLT to alleviate intraocular pressure (IOP) in patients with glaucoma. Read More

Indian J Ophthalmol 2022 Jun;70(6):2036-2037

Department of Glaucoma, Centre for Sight, Hyderabad, Telangana, India.

Indian J Ophthalmol 2022 Jun;70(6):1920-1930

Department of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, Illinois, USA.

The burden of irreversible vision loss from Glaucoma continues to rise. While the disease pathogenesis is not well understood, intraocular pressure (IOP) is the only modifiable risk factor identified to prevent glaucomatous vision loss. Medical management remains the first-line of treatment in most adult glaucomas and the evolution of medical therapy for glaucoma has followed an exponential curve. Read More

Clin Ter 2022 May;173(3):198-202

Clinica Oftalmológica Paredes, Pasto, Nariño, Colombia.

Purpose: The main purpose of this study was to report a case of cystoid macular edema (CME) after gonioscopy-assisted transluminal trabeculotomy (GATT).

Methods: We describe the case of a 73-year-old woman with ocular hypertension and history of cataract surgery combined with posterior vitrectomy and epiretinal membrane peeling 2 years before, who developed CME after uncomplicated GATT procedure.

Results: Uneventful GATT surgery was performed in an eye with ocular hypertension. Read More

JAMA 2022 05;327(20):1998-2012

Casey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, Portland.

Importance: Two 2013 systematic reviews to inform the US Preventive Services Task Force (USPSTF) found insufficient evidence to assess benefits and harms of screening for primary open-angle glaucoma (OAG) in adults.

Objective: To update the 2013 reviews on screening for glaucoma, to inform the USPSTF.

Data Sources: Ovid MEDLINE, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews (to February 2021); surveillance through January 21, 2022. Read More

JAMA 2022 05;327(20):1992-1997

Tufts University School of Medicine, Boston, Massachusetts.

Importance: Glaucoma affects an estimated 2.7 million people in the US. It is the second-leading cause of irreversible blindness in the US and the leading cause of blindness in Black and Hispanic/Latino persons. Read More

Invest Ophthalmol Vis Sci 2022 05;63(5):25

Department of Ophthalmology, NYU Langone Health, New York, New York, United States.

Purpose: The lamina cribrosa (LC) is a leading target for initial glaucomatous damage. We investigated the in vivo microstructural deformation within the LC volume in response to acute IOP modulation while maintaining fixed intracranial pressure (ICP).

Methods: In vivo optic nerve head (ONH) spectral-domain optical coherence tomography (OCT) scans (Leica, Chicago, IL, USA) were obtained from eight eyes of healthy adult rhesus macaques (7 animals; ages = 7. Read More

J Med Case Rep 2022 May 15;16(1):191. Epub 2022 May 15.

Obstetrics and Gynecology Department, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: Ocular vascular occlusion is an extremely rare event, especially in the young population. This diagnosis is always associated with active systemic diseases in young adults and needs thrombophilia workup. Nevertheless, we present the case of a pregnant woman suffering from idiopathic combined central retinal vein and cilioretinal artery occlusion. Read More

JAMA Ophthalmol 2022 Jun;140(6):598-603

Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor.

Importance: If an anatomic narrow angle is not appropriately diagnosed and treated, it can result in acute angle-closure crisis (AACC) and lead to substantial vision loss.

Objective: To identify patients who presented with AACC and assess for factors that may have been associated with risk of developing it.

Design, Setting, And Participants: This population-based retrospective cohort study conducted from January 1, 2001, to December 31, 2015, included a 20% nationwide sample of 1179 Medicare beneficiaries. Read More

BMC Ophthalmol 2022 May 12;22(1):215. Epub 2022 May 12.

Kanto Central Hospital of the Mutual Aid Association of Public School Teachers, Setagaya-ku, Tokyo, Japan.

Background: Although relationship between the retinal vessel caliber (RVC) and glaucoma is well known, there has been a paucity of information on the effects of glaucoma-related optic nerve head (ONH) structural factors on the RVC. Information on this relationship should be useful in studying possible roles of ocular circulation in the development and progression of glaucoma.

Method: Subjects were from Kumejima Study participants aged 40 years and older in Kumejima, Japan. Read More

Neurol India 2022 Mar-Apr;70(2):704-709

Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India.

Background: Idiopathic intracranial hypertension (IIH) is well-described entity in literature. However, large studies on clinical and radiological profile are still very few from the Indian subcontinent.

Aims: To analyze the clinical and radiological profile of IIH and correlation of various clinical and radiological parameters with papilledema and CSF opening pressure. Read More

Arch Soc Esp Oftalmol (Engl Ed) 2022 Apr 20;97(4):234-238. Epub 2021 Nov 20.

Servicio de Oftalmología, Hospital General Obispo Polanco, Teruel, Spain.

A 53-year-old male with no systemic disorders, other than controlled arterial hypertension, presented with asymptomatic, bilateral neurosensory retinal detachment (NRD) detected during a routine revision. The patient reported the use of tadalafil (a phosphodiesterase-5 inhibitor [PDE5I]) for erectile dysfunction. Following suspension of the drug, subretinal fluid reabsorption was confirmed, with the persistence of chronic alterations in the optical coherence tomography (OCT) and the visual field. Read More

Indian J Ophthalmol 2022 05;70(5):1635-1641

Department of Biostatistics, Aravind Eye Hospital and Post-Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.

Purpose: To assess the long-term outcomes of choroidal detachments (CDs) in eyes following trabeculectomy.

Methods: Retrospective comparative case series. Data of patients with CDs following trabeculectomy (5-year period) with or without cataract surgery with a minimum of 3 months of follow-up were included. Read More

Indian J Ophthalmol 2022 05;70(5):1491-1501

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Topiramate-induced acute angle closure (TiAAC) is a potentially vision-threatening side effect of topiramate (TPM) use. The purpose of this article is to review demographic characteristics, clinical features, and management options of TiAAC. A systematic literature search of all reported cases and case series of TiAAC was conducted in the following search engines: PubMed, Web of Science, Google Scholar, Elsevier, and EBSCO. Read More

PLoS One 2022 29;17(4):e0267582. Epub 2022 Apr 29.

Department of of Ophthalmology, School of Medicine, College of Medicine and Health Sciences and Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.

Introduction: Glaucoma is a disease which causes optic nerve damage and remains a major public health concern worldwide. Late presentation is a major risk factor for glaucoma induced blindness. The aim of this study was to assess determinants for late presentation of glaucoma among adult glaucomatous patients. Read More

Cesk Slov Oftalmol 2022 ;78(2):56-62

Purpose: Evaluation of the incidence of pseudoexfoliation (PEX) syndrome and glaucoma in cataract patients operated at our Clinic, with an analysis of possible complications.

Methodology: Retrospective evaluation of medical records of PEX syndrome patients who have undergone cataract surgery at the Gemini Eye Clinic Ostrava-Hrusov was undertaken. The study period was from November 2016 to April 2021. Read More

Klin Monbl Augenheilkd 2022 Apr 26;239(4):610-614. Epub 2022 Apr 26.

Mobile Messungen, Augenmobil AG, Zürich, Zürich, Switzerland.

Purpose: For the elderly in nursery homes, a visit to the ophthalmologist is a burden, which might lead to undertreatment. We have recently started offering a novel ophthalmological service combining onsite examination and telemedical interpretation for patients with limited access to ophthalmological care. This study summarises the frequency of findings of treatable eye diseases after the first year of operation in participants who dropped out from regular ophthalmological control. Read More

Klin Monbl Augenheilkd 2022 Apr 26;239(4):449-453. Epub 2022 Apr 26.

Business and Management, Montpellier University Institute of Business and Management Science, Montpellier, France.

Purpose: In response to the spread of COVID-19 in Switzerland, ophthalmology practices implemented a variety of preventive measures in order to minimise the risk of contamination to their patients and staff. Yet, some studies suggested that over a quarter of all glaucoma patients never returned to the clinic after the first lockdown eased. This raises the question of the factors influencing Patients' likelihood to keep their appointments in this COVID-19 era. Read More

Arch Soc Esp Oftalmol (Engl Ed) 2022 May 22;97(5):244-250. Epub 2022 Apr 22.

Servicio de Reumatología, Hospital Universitario Infanta Sofía, Facultad de Ciencias Biomédicas y de la Salud, Universidad Europea, San Sebastián de los Reyes, Madrid, Spain.

Objective: To estimate the population frequency of uveitis complications and to evaluate their main risk factors in the patients with uveitis from the UVECAM study.

Patients And Methods: Development of complications in 386 patients with uveitis in the whole health area of the province of Toledo (UVECAM study) during a period of 1 year. Description of complications and study of their possible determinants by means of multivariate regression models. Read More

BMC Ophthalmol 2022 Apr 22;22(1):184. Epub 2022 Apr 22.

Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, China.

Background: Pigmented paravenous retinochoroidal atrophy (PPRCA) is a rare fundus disease characterized by the presence of osteoblast-like pigment, atrophy of retinal pigment epithelium (RPE), and choroid deposition along the large retinal veins.

Case Presentation: A 55-year-old Chinese female presented with right eye distention and bilateral vision loss. Osteocyte-like pigmentation and retinal choroidal atrophy distributed along the large retinal veins were seen in the fundus of bilateral eyes. Read More

PLoS One 2022 21;17(4):e0267425. Epub 2022 Apr 21.

Department of Ophthalmology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Objective: Vitreoretinal diseases are common causes of ocular morbidities and blindness. Data on the spectrum of vitreoretinal diseases needs to be studied and known in order to establish appropriate vitreoretinal care setups. The aim of this study was to determine the patterns of vitreoretinal diseases among patients who visited the vitreoretina clinic of University of Gondar Tertiary Eye Care and Training Center, NW Ethiopia (UoG-TECTC). Read More

JAMA Ophthalmol 2022 Jun;140(6):568-576

QIMR Berghofer Medical Research Institute, Brisbane, Australia.

Importance: Keratoconus can be a debilitating corneal ectasia in which the cornea thins, bulges, and steepens into a conical shape. Early features of keratoconus include myopia and irregular astigmatism, which affect vision and can be treated with contact lenses, collagen cross-linking, or, in advanced cases, corneal transplant. Recent estimates of the prevalence of keratoconus based on results of Scheimpflug imaging in young adults are as high as 1. Read More

Niger J Clin Pract 2022 Apr;25(4):395-400

Department of Ophthalmology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.

Background And Aim: To determine the effect of postural changes on intraocular pressure (IOP) among newly diagnosed patients with primary open-angle glaucoma (POAG).

Patients And Methods: This was a cross-sectional observational study of 55 consecutive newly diagnosed patients with POAG attending Glaucoma clinics at a Federal Teaching Hospital in Abakaliki, Ebonyi state, from July to September 2017. Patients IOPs were measured in the sitting position, supine without a pillow, and supine with pillow positions using Perkin's handheld applanation tonometer. Read More