522 results match your criteria Glaucoma Secondary Congenital


Ologen augmentation of Ahmed valves in pediatric glaucomas.

J AAPOS 2022 Jun 10;26(3):122.e1-122.e6. Epub 2022 May 10.

Division of Ophthalmology, Ann & Robert H. Lurie Children's Hospital of Chicago; Department of Ophthalmology, Northwestern University Feinberg School of Medicine. Electronic address:

Background: We previously showed that Ologen increased success and survival rates of Ahmed glaucoma devices in a small number of children. The current study analyzed the same surgical technique in an expanded cohort.

Methods: Retrospective interventional case series of children who underwent Ologen augmentation of Ahmed glaucoma device (OAGD) from 2018 to 2021 with ≥6 months' postoperative follow-up. Read More

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Clinical Analysis of Pediatric Glaucoma in Central China.

Front Med (Lausanne) 2022 1;9:874369. Epub 2022 Apr 1.

Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, China.

Purpose: We aimed to describe the characteristics, epidemiology, management, and outcomes of glaucoma in pediatric patients in central China.

Methods: This study retrospectively analyzed inpatients with pediatric glaucoma at Henan Provincial People's Hospital, Henan Eye Institute, and Henan Eye Hospital between 2017 and 2020.

Results: Overall, 239 cases (276 eyes) of pediatric glaucoma in patients, comprising 87 girls (36. Read More

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Secondary glaucoma caused by a special type of persistent fetal vasculature.

Int Ophthalmol 2022 Apr 13. Epub 2022 Apr 13.

Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road, No. 1665, Shanghai, 200092, China.

Purpose: To investigate the clinical features and surgical outcomes in infants with glaucoma secondary to a special anterior-anterior type of persistent fetal vasculature (AAPFV).

Methods: This study retrospectively reviewed the medical records of infants who underwent of the synechialysis, pupilloplasty, with or without lensectomy and limbal vitrectomy due to AAPFV and with at least 6 months of postoperative follow-up.

Results: Eleven patients were included. Read More

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Primary intraocular lens implantation in infants with unilateral congenital cataract operated before 12 weeks of age.

Acta Ophthalmol 2022 Apr 11. Epub 2022 Apr 11.

Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.

Purpose: The aim of this study was to report visual outcome and safety after cataract surgery with primary intraocular lens implantation before 12 weeks of age.

Methods: Infants with visually significant unilateral congenital cataract having primary IOL implantation in the capsular bag before 12 weeks of age in 2007-2016 were enrolled for a prospective study examination in 2017. The medical records were also reviewed. Read More

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Microcatheter-assisted circumferential trabeculotomy in primary congenital glaucoma.

Saudi J Ophthalmol 2021 Apr-Jun;35(2):117-121. Epub 2022 Feb 18.

Department of Ophthalmology, Faculty of medicine, Minia University, 61519, El-Minia, Egypt.

Purpose: To study circumferential trabeculotomy for congenital glaucoma using Glaucolight illuminated microcatheter.

Methods: This was a prospective, uncontrolled, consecutive interventional study of 25 eyes of 25 patients with primary congenital glaucoma (PCG) underwent circumferential trabeculotomy done with an illuminated microcatheter through a period of 18-24 months in ophthalmology department, faculty of medicine, Minia University, Egypt. Patients' data of 12 months' follow-up were recorded. Read More

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February 2022

First XEN implantation in Axenfeld- Rieger syndrome: A case report and literature review.

Am J Ophthalmol Case Rep 2022 Jun 10;26:101486. Epub 2022 Mar 10.

Edith Wolfson Medical Center, 62 Halohamim st., Holon, Israel.

Purpose: To present the first report of a XEN45 gel stent implantation in a female with Axenfeld-Rieger syndrome (ARS), a rare congenital anomaly caused by abnormal neural crest migration during early embryogenesis. This shows promise as new minimally invasive therapeutic option in the treatment of secondary glaucoma in ARS.

Observations: A 31-year-old female with known sporadic ARS was evaluated and treated at the Edith Wolfson Medical Center in Holon, Israel. Read More

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Childhood blindness and associated factors: An observational study at the district disability rehabilitation centre, West Tripura district, India.

J Family Med Prim Care 2021 Dec 27;10(12):4497-4501. Epub 2021 Dec 27.

District Disability Rehabilitation Officer, West Tripura District, Department of Health & Family Welfare, Govt. of Tripura, India.

Background: In India, about 50% of all childhood blindness is either preventable or treatable. Hence, controlling childhood blindness may be an effective way to reduce blindness in this country in the long run. Strategies to combat childhood blindness require accurate data regarding its magnitude, distribution, and determinants in a population. Read More

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December 2021

Glaucoma and risk factors three years after congenital cataract surgery.

BMC Ophthalmol 2022 Mar 12;22(1):118. Epub 2022 Mar 12.

Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Background: This study aimed to identify the incidence of and risk factors for postoperative glaucoma-related adverse events at various time points after congenital cataract surgery.

Methods: This retrospective cohort study enrolled 259 eyes from 174 patients (surgical age ≤ 7 years) who underwent congenital cataract surgery. All surgical procedures were conducted at the Eye Hospital of Wenzhou Medical University between May 2011 and March 2019. Read More

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Bilateral Phakomatosis Cesiomarmorata With Ocular Melanocytosis and Secondary Glaucoma.

Cureus 2022 Mar 5;14(3):e22861. Epub 2022 Mar 5.

Pediatric Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, SAU.

Phakomatosis pigmentovascularis (PPV) is a family of rare congenital diseases where vascular malformation coexists with melanocytic, dermal, or ocular lesions. The cesiomarmorata type is even rarer, and most such cases are reported with unilateral occurrence. We present an atypical case of a patient with bilateral phakomatosis cesiomarmorata, bilateral ocular melanocytosis, and bilateral glaucoma. Read More

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Secondary developmental glaucoma in eyes with congenital aphakia.

Indian J Ophthalmol 2022 Mar;70(3):834-836

Department of Ophthalmology and Visual Sciences and Pathology, University of Illinois Eye and Ear Infirmary, Chicago, United States.

Purpose: To describe the clinical spectrum and management of glaucoma in congenital aphakia.

Methods: The demographics and clinical spectrum of eyes with congenital aphakia with and without glaucoma were compared, and management outcomes of congenital aphakia cases with glaucoma were studied retrospectively between April 2000 and June 2020.

Results: There were a total of 168 eyes (84 subjects) with a diagnosis of congenital aphakia, of which 29 eyes of 18 subjects were diagnosed with glaucoma. Read More

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Childhood glaucoma registry in Germany: initial database, clinical care and research (pilot study).

BMC Res Notes 2022 Feb 10;15(1):32. Epub 2022 Feb 10.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.

Objective: The aim of this prospective pilot study is to establish an initial database to register patients diagnosed with different types of childhood glaucoma and the set-up of a national registry for childhood glaucoma (ReCG) in Germany. 28 children with different types of diagnosed childhood glaucoma, who were admitted and treated at the Childhood Glaucoma Center of the University Medical Center Mainz, Germany were included. Main outcome measures were the type of childhood glaucoma, mean intraocular pressure (IOP) and genetic data of the patients. Read More

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February 2022

Bilateral congenital stromal iris cyst with secondary glaucoma.

Am J Ophthalmol Case Rep 2022 Mar 20;25:101261. Epub 2022 Jan 20.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India.

Purpose: To report a case of bilateral congenital stromal iris cyst in a neonate.

Observations: A one-month-old male child was brought with complaints of watering in both eyes and enlargement of the left eye since birth. Examination under anesthesia revealed an elevated IOP in both the eyes. Read More

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Neonatal-Onset Congenital Ectropion Uveae May Be Caused by a Distinct CYP1B1 Pathologic Variant.

Am J Ophthalmol 2022 Jul 24;239:54-65. Epub 2022 Jan 24.

From the Advanced Eye Center and Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Purpose: To report underlying genetic variants of recently described distinct phenotype of newborn glaucoma: neonatal-onset congenital ectropion uveae (NO-CEU).

Design: Prospective cohort study.

Methods: Setting: tertiary care teaching institute. Read More

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Multiple XEN Gel Stents for Refractory Pediatric Glaucoma.

J Pediatr Ophthalmol Strabismus 2022 Jan-Feb;59(1):e11-e14. Epub 2022 Jan 1.

Although trabeculotomy and goniotomy are currently the mainstay of surgical management for congenital glaucoma, XEN Gel Stent (Allergan) implantation and other microinvasive glaucoma surgery technologies may offer the advantage of having a lower risk of postoperative complications than conventional techniques. A 10-year-old boy presented with aphakic glaucoma in his left eye secondary to previous cataract surgery. Intraocular pressure (IOP) in the left eye at initial presentation was 31 mm Hg with maximal tolerated medical therapy. Read More

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January 2022

Microcatheter-Assisted Circumferential Trabeculotomy in Primary Congenital Glaucoma: Long-Term Clinical Outcomes.

J Clin Med 2022 Jan 14;11(2). Epub 2022 Jan 14.

Ophthalmology Unit, Azienda USL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.

Purpose: The purpose of this study was to report the long-term efficacy and clinical outcomes of microcatheter-assisted circumferential trabeculotomy (MCT) in children with primary congenital glaucoma (PCG).

Methods: This is a single-center retrospective study including consecutive children with PCG who underwent MCT with > two years follow up. The primary outcome was surgical success, defined as intraocular pressure (IOP) ≤ 21 mmHg with (qualified) or without (complete) medications, measured at six months, one year, and then annually. Read More

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January 2022

Characteristics and long-term outcomes of childhood glaucoma: a retrospective-cohort study.

F1000Res 2021 1;10:165. Epub 2021 Mar 1.

Glaucoma Research Unit, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

: To evaluate the clinical characteristics and treatment outcomes of patients with childhood glaucoma. : We retrospectively reviewed the data of patients with childhood glaucoma who visited the glaucoma clinics at the Queen Sirikit National Institute of Child Health and the King Chulalongkorn Memorial Hospital between January 2008 and January 2018. The diagnosis was based on the Childhood Glaucoma Research Network classification. Read More

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January 2022

Approach to childhood glaucoma: A review.

Clin Exp Ophthalmol 2022 03 25;50(2):232-246. Epub 2022 Jan 25.

Speciality of Ophthalmology, Save Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

Childhood glaucoma represents a heterogenous group of rare ocular conditions that may result in significant sight threatening complications related to elevated intraocular pressure (IOP). It can be classified as either primary or secondary and the latter may have systemic associations. This review will be based on the work of the childhood glaucoma research network (CGRN) and will focus on the diagnosis and management of the most common types of childhood glaucoma. Read More

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First Results from the Prospective German Registry for Childhood Glaucoma: Phenotype-Genotype Association.

J Clin Med 2021 Dec 21;11(1). Epub 2021 Dec 21.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

Childhood glaucoma is a heterogeneous disease and can be associated with various genetic alterations. The aim of this study was to report first results of the phenotype-genotype relationship in a German childhood glaucoma cohort. Forty-nine eyes of 29 children diagnosed with childhood glaucoma were prospectively included in the registry. Read More

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December 2021

Trabeculotomy Versus Combined Trabeculotomy-Trabeculectomy for Management of Primary Congenital Glaucoma.

J Glaucoma 2022 May 10;31(5):346-350. Epub 2022 Jan 10.

Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science.

Prcis: Trabeculotomy (T) alone is as safe and effective as combined trabeculotomy-trabeculectomy (TT) in patients with primary congenital glaucoma (PCG) and requires significantly fewer examinations under anesthesia in the postoperative period.

Purpose: The purpose of this study was to compare the outcomes of T and combined TT as the initial surgical procedure for patients with PCG.

Methods: In this retrospective study, medical records of patients who had undergone T or TT as the initial procedure for PCG were reviewed. Read More

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Twenty-Years of Experience in Childhood Glaucoma Surgery.

J Clin Med 2021 Dec 8;10(24). Epub 2021 Dec 8.

Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr. 1, 55131 Mainz, Germany.

To quantify the results of childhood glaucoma treatment over time in a cohort of children with different types of childhood glaucoma. A retrospective cohort study of consecutive cases involving children with primary congenital glaucoma, primary juvenile, and secondary juvenile glaucoma at the Childhood Glaucoma Center, University Medical Center Mainz, Germany from 1995 to 2015 was conducted. The main outcome measure was the long-term development of intraocular pressure. Read More

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December 2021

Phacomatosis pigmentovascularis with sturge-weber syndrome and congenital glaucoma: A rare case report.

Eur J Ophthalmol 2021 Dec 17:11206721211067886. Epub 2021 Dec 17.

Dept. of Ophthalmology, 29988JIPMER, Puducherry, Puducherry, India.

Phacomatosis pigmentovascularis (PPV) is a rare congenital disease characterized by the co-existence of cutaneous vascular malformation and pigmentary nevi with or without extracutaneous systemic involvement. Here, we present a 2-month old child diagnosed with phacomatosis cesioflammea type of PPV with Sturge-Weber syndrome and secondary congenital glaucoma of the left eye. She underwent combined trabeculotomy and trabeculectomy in the left eye for glaucoma and was started on anti-epileptics for seizure control following pediatric evaluation. Read More

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December 2021

Descemet Stripping Endothelial Keratoplasty in Microcornea for Pseudophakic Bullous Keratopathy With Anterior Chamber Intraocular Lens.

Cureus 2021 Nov 4;13(11):e19262. Epub 2021 Nov 4.

Ophthalmology, Armed Forces Medical College, Pune, IND.

To report a case of bilateral pseudophakic bullous keratopathy (PBK) in a patient having bilateral microcornea with pre-existing anterior chamber intraocular lens (ACIOL) who underwent Descemet stripping endothelial keratoplasty (DSEK) with a successful postoperative visual outcome. A 36-year-old female, diagnosed with microcornea and congenital cataract in both eyes underwent lens aspiration sequentially followed by ACIOL implantation in both eyes. The patient reported to our centre and was diagnosed with bilateral PBK with ACIOL with microcornea. Read More

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November 2021

The Effectiveness of Propranolol in Managing Hemorrhagic Choroidal and Exudative Retinal Detachment following Ahmed Glaucoma Valve Implantation in Sturge-Weber Syndrome: Case Report and Literature Review.

Case Rep Ophthalmol 2021 Sep-Dec;12(3):859-869. Epub 2021 Oct 25.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Sturge-Weber syndrome (SWS) is a congenital neurological disorder that is characterized by hamartomas involving the skin, brain, and eyes and marked by the presence of the facial port-wine stain, which consequently leads to various ocular complications. Among all ocular comorbidities, glaucoma is the most frequently witnessed in SWS patients with a prevalence of 30%-70%. If glaucoma is refractory to conventional medical management, surgical intervention can be considered. Read More

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October 2021

Crystalline lens alterations in congenital aniridia.

Arch Soc Esp Oftalmol (Engl Ed) 2021 Nov 12;96 Suppl 1:38-51. Epub 2021 Jun 12.

Vissum Innovation, Alicante, Spain; División de Oftalmología, Universidad Miguel Hernández, Alicante, Spain. Electronic address:

Congenital aniridia is a rare genetic disease associated with mutations in the PAX6 gene. Changes in the lens in aniridia can be alterations of size and shape, of position - which generally reveal zonular weakness and determines subluxation of the lens - and mainly changes in transparency, cataracts, with variable morphology of polar, cortical, subcapsular, lamellar, and more rarely, nuclear cataract. Visual acuity and quality of vision in patients with congenital aniridia complicated by cataracts can be improved by carefully planned surgery, when lack of media transparency justifies surgical indication. Read More

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November 2021

Epidemiological Characteristics of Inpatients Undergoing Surgery for Glaucoma at Tianjin Eye Hospital from 2013 to 2017.

J Ophthalmol 2021 8;2021:3628481. Epub 2021 Nov 8.

Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin 300020, China.

Purpose: To analyze the epidemiological characteristics of inpatients who underwent surgery for glaucoma at Tianjin Eye Hospital from 2013 to 2017.

Methods: All glaucoma inpatients who underwent surgery at Tianjin Eye Hospital from 2013 to 2017 were evaluated. The relationships of age and sex with different types of glaucoma were analyzed. Read More

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November 2021

Clinical and Ultrasound Biomicroscopic Characteristics of Congenital Fibrovascular Pupillary Membrane-Induced Secondary Glaucoma.

Front Med (Lausanne) 2021 28;8:763137. Epub 2021 Oct 28.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

The purpose of this study was to describe and summarize the clinical features of congenital fibrovascular pupillary membrane-induced secondary glaucoma (CFPMSG). Cross-sectional case series. Eyes of 32 patients with CFPMSG were enrolled. Read More

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October 2021

Ophthalmological knowledge of Family Health Network physicians working as first care providers in Brazil.

Rev Assoc Med Bras (1992) 2021 Jun;67(6):795-799

Faculdade de Medicina de Botucatu - Botucatu (SP), Brazil.

Objective: First care providers working in the Brazilian Unified Health System are often physicians from the Family Health Program. Their knowledge on ophthalmology could indicate whether there is a need for training to decrease ophthalmological demands to secondary or tertiary health levels.

Methods: A cross-sectional observational study based on an electronic questionnaire was conducted to evaluate the ophthalmological knowledge of Family Health Program physicians working at the VI Regional Health Department, Sao Paulo, Brazil. Read More

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In-the-Bag Versus Ciliary Sulcus Secondary Intraocular Lens Implantation for Pediatric Aphakia: A Prospective Comparative Study.

Am J Ophthalmol 2022 04 13;236:183-192. Epub 2021 Oct 13.

Zhongshan Ophthalmic Center (Z.L., H.L., G J., X.T., B.Q., L.J., X.C., W.W., X. H., J.X., M.H., N.C., W.C., L.L., Y.L.) State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, Guangdong, China. Electronic address:

Purpose: To compare outcomes of in-the-bag vs ciliary sulcus secondary intraocular lens (IOL) implantation for pediatric aphakia.

Design: Prospective interventional case series.

Methods: This institutional study was conducted in 202 children (355 aphakic eyes) diagnosed as having congenital cataracts and who underwent cataract extraction before age 24 months. Read More

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Long-term outcome of primary intraocular lens implantation in bilateral congenital cataract in infants with a median age of 35 days at surgery: a case series.

BMJ Open Ophthalmol 2021 30;6(1):e000836. Epub 2021 Sep 30.

Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.

Objective: To evaluate the long-term visual outcome and safety after bilateral cataract surgery with primary intraocular lens (IOL) implantation in infants with visually significant cataract at birth operated before 12 weeks of age.

Methods And Analysis: Medical records of infants with congenital cataract who had bilateral surgery with primary IOL implantation before 12 weeks of age at Oslo University Hospital between 2007 and 2016 were retrospectively reviewed. Fifteen infants (30 eyes) were enrolled for a prospective study examination in 2017. Read More

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September 2021