192 results match your criteria Glaucoma Plateau Iris

Prevalence of Plateau Iris Syndrome among Patients Presenting with Primary Angle Closure and Primary Angle-Closure Glaucoma in a Tertiary Eye Care Hospital.

Middle East Afr J Ophthalmol 2021 Oct-Dec;28(4):221-225. Epub 2022 Apr 30.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Purpose: Glaucoma is a leading cause of visual impairment worldwide, and plateau iris syndrome (PIS) is the most common nonpupillary block mechanism of angle closure. This study aims to assess the prevalence of PIS among Saudi population.

Methods: It is a prospective observational study that examined patients previously diagnosed with chronic angle closure. Read More

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Imaging of the Ciliary Body: A Major Review.

Semin Ophthalmol 2022 Jun 11:1-13. Epub 2022 Jun 11.

VST Centre for Glaucoma Services, L V Prasad Eye Institute, Hyderabad, India.

Purpose: We conducted a systematic search of literature to understand the various methods of imaging of the ciliary body.

Methods: PubMed, Science Direct, Cochrane Library and Google Scholar were searched comprehensively and systematically to find studies related to the various modalities of ciliary body imaging.

Results: The various ciliary body parameters that have been described are Ciliary body thickness, Ciliary body length, ciliary muscle thickness, ciliary process length, ciliary muscle length, ciliary muscle anterior length, trabecular ciliary process distance and Iris ciliary process distance. Read More

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Diagnostic performance of anterior segment optical coherence tomography in detecting plateau iris.

BMJ Open Ophthalmol 2022 23;7(1):e000931. Epub 2022 Mar 23.

Ophthalmology, Rajavithi Hospital, Bangkok, Thailand.

Objective: To evaluate the diagnostic performance of manual grading of anterior segment optical coherence tomography (AS-OCT) in detection of plateau iris configuration (PIC) based on the presence of standardised ultrasound biomicroscopy (UBM) criteria in at least two quadrants; namely, clinical diagnosis of PIC (DxPIC).

Methods And Analysis: In this cross-sectional study, paired AS-OCT and UBM images were evaluated by three glaucoma specialists. AS-OCT was classified into two mechanisms, PIC versus non-PIC, of primary angle closure disease (PACD) and AS-OCT-PIC diagnostic performance was tested with DxPIC. Read More

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The ocular biometry characteristics of young patients with primary angle-closure glaucoma.

BMC Ophthalmol 2022 Apr 2;22(1):150. Epub 2022 Apr 2.

Eye Center of Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, China.

Background: Although primary angle-closure glaucoma (PACG) mainly occurs in elderly people, diagnosis of PACG in young patients is not uncommon. So far, there is no article specialized on the ocular anatomical characteristics in these patients.In this study, ocular anatomical characteristics in young PACG patients are analyzed. Read More

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Prevalence of Plateau Iris in Primary Angle Closure Glaucoma: An Egyptian Hospital Based Ultrasound Biomicroscopy Study.

Clin Ophthalmol 2022 25;16:541-550. Epub 2022 Feb 25.

Department of Ophthalmology, Tanta University, Tanta, Elgharbia Province, Egypt.

Purpose: To determine the distribution and the anatomical characteristics of plateau iris (PI) in primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM).

Methods: Fifty UBM images of PACG cases were studied over one year by retrospective analysis. The data from UBM images including angle opening distance at 500 and 750 μm (AOD500 and AOD750), trabecular-iris angle (TIA), angle recess area at 750 μm (ARA750), maximum ciliary body thickness (CBTmax), anterior placement of ciliary processes (APCP), central anterior chamber depth (CACD), axial lens thickness (ALT), and ciliary sulcus status were analyzed and compared between the PI and non-PI cases. Read More

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February 2022

Early occurrence of primary angle-closure glaucoma in a patient with retinitis pigmentosa and CRB1 gene variations.

Arq Bras Oftalmol 2022 Feb 14. Epub 2022 Feb 14.

Department of Opthalmology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

We describe the case of a 15-year-old girl with decreased visual acuity associated with elevated intraocular pressure in both eyes and angle closure on gonioscopy. She also presented attenuation of retinal vessels and optic disc pallor with large excavation in the left eye. Ultrasound biomicroscopy revealed an anteriorly positioned ciliary body and absence of ciliary sulcus, confirming the plateau iris configuration. Read More

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February 2022

Glaucoma Progression After Lens Extraction in Primary Angle-closure Glaucoma According to Angle-closure Mechanism.

J Glaucoma 2022 04;31(4):261-267

Department of Ophthalmology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, South Korea.

Prcis: Long-term prognosis of primary angle-closure was assessed after lens extraction (LE) according to different mechanisms of angle closure (AC). Patients with pupillary block (PB) had a higher probability of glaucomatous progression than patients with plateau iris configuration (PIC).

Purpose: The aim was to investigate and compare the clinical characteristics and long-term prognosis of primary angle-closure disease (PACD) after LE according to different mechanisms of AC. Read More

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Case report: Cataract extraction/lensectomy, excisional goniotomy and transscleral cyclophotocoagulation: Affordable combination MIGS for plateau iris glaucoma.

J Natl Med Assoc 2022 Feb 5;114(1):38-41. Epub 2022 Jan 5.

Advanced Eyecare of New York, 29 W 127(th) St, New York, NY, USA.

We report the successful treatment of angle closure glaucoma and plateau iris with combined early cataract surgery/lensectomy, goniotomy, and transscleral cyclophotocoagulation. The underlying mechanism of angle closure and plateau iris was addressed with cataract extraction and goniosynechiolysis. Goniotomy was used to enhance trabecular meshwork outflow and lower intraocular pressure, and the "slow burn" transscleral cyclophotocoagulation was safely performed to reduce the size of the ciliary processes. Read More

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February 2022

Predictibility of the efficacy of peripheral iridotomy in primary angle closure: Utility of UBM.

J Fr Ophtalmol 2022 Feb 1;45(2):201-206. Epub 2022 Jan 1.

Centre Explore Vision, 4, rue des Grandes Terres, 92500 Rueil-Malmaison, France; Centre Explore Vision, 10, rue Croix-des-Petits-Champs, 75001 Paris, France.

Purpose: To assess the utility of UBM in the management of primary angle closure (PAC) and assessing the predictability of peripheral iridotomy (PI) in re-opening the closed angle.

Design: Retrospective clinical study.

Subjects: Patients with suspicion of PAC. Read More

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February 2022

[Progress in the research of plateau iris].

Y J Yan L L Wu

Zhonghua Yan Ke Za Zhi 2022 Jan;58(1):51-57

Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China.

Primary angle closure glaucoma is the main type of glaucoma in Asia. Plateau iris is one of the important mechanisms of non-pupil block. After years of research, the concept of plateau iris has been gradually clarified, and its epidemiology, pathogenesis, diagnosis and treatment have been gradually recognized. Read More

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January 2022

Angle Closure with Patent Laser Peripheral Iridotomy - An Unusual Complication.

Int J Appl Basic Med Res 2021 Oct-Dec;11(4):270-272. Epub 2021 Nov 17.

Department of Ophthalmology, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India.

A 41-year-old female presented with diminished vision in both eyes with recurrent episodes of pain, redness, and watering. With a provisional diagnosis of primary angle-closure glaucoma in the left eye and primary angle closure in the right eye, anti-glaucoma medications were started in the left eye and laser peripheral iridotomy was done in both eyes. Follow-up showed patent iridotomy in both eyes and dilated fundoscopy revealed total cupping in the left eye. Read More

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November 2021

[Malignant glaucoma and plateau iris syndrome: A case report].

J Fr Ophtalmol 2022 Feb 15;45(2):e95-e98. Epub 2021 Sep 15.

Service d'ophtalmologie, hôpital d'instruction des Armées de Begin, DHU Vision et Handicap, 69, avenue de Paris, 94160 Saint-Mandé, France.

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February 2022

Predictive Equation for Angle Opening Distance at 750 μm After Laser Peripheral Iridotomy in Primary Angle Closure Suspects.

Front Med (Lausanne) 2021 12;8:715747. Epub 2021 Aug 12.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

The aim of this study was to investigate the changes in anterior segment parameters as assessed by ultrasound biomicroscopy (UBM) after laser peripheral iridotomy (LPI) and to propose a prediction equation for the width of the angle after LPI. This was a prospective study. The participants included 100 subjects with primary angle closure suspect (PACS). Read More

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Diagnostic imaging of the ciliary body: Technologies, outcomes, and future perspectives.

Eur J Ophthalmol 2022 Jan 7;32(1):75-88. Epub 2021 Jul 7.

Department of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Madrid, Spain.

The ciliary body (CB) is part of the uvea and is a complex, highly specialized structure with multiple functions and significant relationships with nearby structures. Its functions include the aqueous humor (AH) production in the ciliary processes, the regulation of the AH output through the uveoscleral pathway, and accommodation, which depends on the ciliary muscle. Also, the CB is an important determinant of angle width as it forms part of the ciliary sulcus. Read More

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January 2022

The prevalence and break down of narrow anterior chamber angle pathology presenting to a general ophthalmology clinic.

Medicine (Baltimore) 2021 Jun;100(24):e26195

East Kent Hospitals University NHS Foundations Trust, New Hayesbank NHS Eye Clinic, United Kingdom.

Abstract: To approximate the breakdown of narrow anterior chamber angle conditions, on general ophthalmology clinics, in the predominantly white population of the South East Kent region in the United Kingdom.A review was done of all patients attending a secondary care ophthalmology general clinic over a 3-year period. Patients were assessed with: slitlamp biomicroscopy with indentation gonioscopy; SD optical coherence tomography, Humphrey visual field analyzer, and high frequency ultrasound and categorized into various narrow angle conditions. Read More

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Bilateral angle-closure during hospitalization for coronavirus disease-19 (COVID-19): A case report.

Eur J Ophthalmol 2022 May 22;32(3):NP75-NP82. Epub 2021 Apr 22.

Department of Neurosciences, Biomedicine and Movement Sciences, Eye Clinic, University of Verona, Verona, Italy.

Purpose: This report describes a case of bilateral primary angle closure (PAC) progressing to unilateral end-stage primary angle closure glaucoma (PACG) associated with treatment for coronavirus disease-19 (COVID-19) infection.

Methods: A 64-year-old man came to our attention because of blurred vision after a 2-month hospital stay for treatment of COVID-19 infection. Examination findings revealed PACG, with severe visual impairment in the right eye and PAC in the left eye due to plateau iris syndrome. Read More

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Deep Learning for Anterior Segment Optical Coherence Tomography to Predict the Presence of Plateau Iris.

Transl Vis Sci Technol 2021 01 6;10(1). Epub 2021 Jan 6.

Department of Ophthalmology, Rajavithi Hospital, Bangkok, Thailand.

Purpose: The purpose of this study was to evaluate the diagnostic performance of deep learning (DL) anterior segment optical coherence tomography (AS-OCT) as a plateau iris prediction model.

Design: We used a cross-sectional study of the development and validation of the DL system.

Methods: We conducted a collaboration between a referral eye center and an informative technology department. Read More

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January 2021

Comparing the Effect of Lens Extraction With Endocycloplasty to Lens Extraction Alone in Eyes With Plateau Iris Configuration: Pilot Study.

J Glaucoma 2021 05;30(5):436-443

Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School at The University of Texas Health Science Center at Houston.

Precis: Lens extraction with endocycloplasty (LE/ECPL) results in greater angle deepening than LE alone in plateau iris eyes. This study directly compares an LE/ECPL treatment group with a control group.

Purpose: Quantitatively determine the effect of LE/ECPL versus LE alone for eyes with plateau iris configuration/plateau iris syndrome (PIC/PIS) on angle parameters. Read More

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The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence.

J Clin Med 2021 Jan 11;10(2). Epub 2021 Jan 11.

Ophthalmic Institute, ASST Fatebenefratelli-Sacco, 20121 Milan, Italy.

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. Read More

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January 2021

Outcomes of combined gonioscopy-assisted transluminal trabeculotomy and goniosynechialysis in primary angle closure: a retrospective case series.

Int Ophthalmol 2021 Apr 3;41(4):1223-1231. Epub 2021 Jan 3.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Purpose: To evaluate the additional intraocular pressure (IOP) lowering effect of gonioscopy-assisted transluminal trabeculotomy (GATT) to contemporary goniosynechialysis (GSL) in endeavouring to abolish subsequent occlusion after chronic iridotrabecular contact in primary angle closure (PAC) patients.

Methods: A retrospective case series of all PAC eyes underwent GATT + GSL with or without phacoemulsification and intraocular lens implantation (PEA + IOL) from December 2016 to May 2018 were recruited. IOP and the number of anti-glaucoma medications were compared pre- and post-operatively by Wilcoxon signed-rank test. Read More

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Detection of primary angleclosure suspect with different mechanisms of angle closure using multivariate prediction models.

Acta Ophthalmol 2021 Jun 30;99(4):e576-e586. Epub 2020 Sep 30.

Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Purpose: We had found that a multivariate prediction model used for the detection of primary angle-closure suspects (PACS) by combining multiple static and dynamic anterior segment optical coherence tomography (ASOCT) parameters had an area under the receiver operating characteristic curve (AUC) of 0.844. We undertook this study to evaluate this method in screening of PACS with different dominant mechanisms of angle closure (AC). Read More

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Using Anterior Segment Optical Coherence Tomography (ASOCT) Parameters to Determine Pupillary Block Versus Plateau Iris Configuration.

J Glaucoma 2020 11;29(11):1036-1042

Ruiz Department of Ophthalmology and Visual Science, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

PRéCIS:: The potential parameters for differentiating pupillary block (PB) from plateau iris configuration (PIC) on anterior segment optical coherence tomography (ASOCT) are lens/pupil size parameters and angles. Further study is needed to determine a landmark peripheral to the centroid of the iris.

Purpose: Investigate anterior segment parameters to distinguish between 2 mechanisms of angle closure, PB and PIC, using swept-source Fourier domain ASOCT. Read More

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November 2020

Plateau iris syndrome and angle-closure glaucoma in a patient with nail-patella syndrome.

Am J Ophthalmol Case Rep 2020 Dec 20;20:100886. Epub 2020 Aug 20.

Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, New York, NY, 10003, USA.

Purpose: To describe a case of plateau iris syndrome (PIS) and angle-closure glaucoma (ACG) in a patient with nail-patella syndrome (NPS).

Observation: A 33 year-old woman of Slovakian ancestry from Norway with a history of NPS presented with angle-closure secondary to plateau iris. At the time of her NPS diagnosis, she had no ocular pathology. Read More

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December 2020

Size Matters for Interplicata Diameter: A Case-Control Study of Plateau Iris.

Ophthalmol Glaucoma 2020 Nov - Dec;3(6):475-480. Epub 2020 Jul 2.

W. K. Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan; Department of Ophthalmology & Visual Science, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address:

Purpose: Ultrasound biomicroscopy (UBM) has been used to characterize anterior segment dimensions in plateau iris configuration (PIC), but transverse measurements between the recesses of the ciliary sulcus (sulcus-to-sulcus diameter [STSD]) and the ciliary body processes (interplicata diameter [IPD]) have not been reported. We measured STSD and IPD and compared these among eyes with PIC, primary angle closure (PAC), and control eyes with open angles.

Design: Retrospective, cross-sectional clinical study. Read More

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September 2021

Plateau Iris and Severity of Primary Angle Closure Glaucoma.

Am J Ophthalmol 2020 12 29;220:1-8. Epub 2020 Jul 29.

Singapore Eye Research Institute, Singapore; Singapore National Eye Centre, Singapore; Duke-National University of Singapore Medical School, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

Purpose: To compare the distribution of plateau iris in eyes across varying severity of primary angle closure glaucoma (PACG) using standardized ultrasound biomicroscopy (UBM) criteria.

Design: Cross-sectional study.

Methods: UBM was performed on 210 patients with PACG who had previously undergone laser peripheral iridotomy. Read More

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December 2020

Evaluation of anterior chamber angle by van Herick grading and ultrasound biomicroscopy in light and dark conditions for finding appositional angle closure and plateau iris configuration.

Acta Ophthalmol 2021 Feb 22;99(1):e86-e95. Epub 2020 Jun 22.

Kanto Central Hospital of the Mutual Aid Association of Public School Teachers, Setagaya, Tokyo, Japan.

Purpose: To evaluate association of the van Herick (VH) grades with the ultrasound biomicroscopic (UBM) parameters, appositional irido-trabecular contact (A-ITC) and plateau iris (PI) in a randomly sampled population.

Methods: A 10% random sample of all residents aged 40 or older of the Kumejima study underwent UBM under dark and light conditions in the four quadrants of right eyes.

Results: Of 301 right eyes with eligible UBM images, 101 (33. Read More

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February 2021

Quantification of Iridotrabecular Contact in Primary Angle-Closure Disease.

J Glaucoma 2020 08;29(8):681-688

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Precis: Iridotrabecular contact (ITC), a measure of angle closure, can be quantified along with other angle parameters on anterior segment optical coherence tomography (ASOCT). Hence, angle changes and angle closure mechanisms can be detected predicting the efficacy of iridotomy.

Purpose: To assess 360-degree ITC and ocular parameter changes, after laser peripheral iridotomy (LPI), in primary angle-closure disease (PACD) subgroups. Read More

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Drug-induced Acute Angle-closure Glaucoma: A Review.

J Curr Glaucoma Pract 2019 Sep-Dec;13(3):104-109

Department of Ophthalmology, UCI Health Gavin Herbert Eye Institute, University of California, Irvine, California, USA.

Aim: Our goal is to review current literature regarding drug-induced acute angle-closure glaucoma (AACG) and provide ophthalmologists and general practitioners with a thorough understanding of inciting medications and treatment pitfalls to be avoided.

Background: Drug-induced AACG is an ophthalmological emergency that ophthalmologists and general practitioners should be familiar with, given its potentially blinding consequences. Common anatomical risk factors for AACG include a shallow anterior chamber depth, short axial length, plateau iris configuration, thick lens, anteriorly positioned lens, and rarely, intraocular tumor. Read More

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Exploring the Occurrence Mechanisms of Acute Primary Angle Closure by Comparative Analysis of Ultrasound Biomicroscopic Data of the Attack and Fellow Eyes.

Biomed Res Int 2020 24;2020:8487907. Epub 2020 Apr 24.

Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Purpose: To explore the anatomical characteristics and occurrence mechanisms of acute primary angle closure (APAC) by comparing the quantitative data of UBM images of the APAC and fellow eyes.

Methods: 131 patients (262 eyes) were studied over five years by retrospective analysis. The quantitative data from UBM images including angle opening distance at 500 m (AOD500), trabecular-iris angle (TIA), iris convexity (IC), iris span (IS), iris-lens angle (ILA), iris-lens contact distance (ILCD), iris-ciliary process angle (ICPA), and limbus-ciliary body angle (LCBA) were retrospectively recorded; comparative analysis of the APAC and fellow eyes was performed. Read More

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February 2021

Argon Laser Iridoplasty for Plateau Iris Syndrome: Long-Term Outcomes of 48 Eyes.

J Glaucoma 2020 04;29(4):e27

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto ON, Canada.

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