717 results match your criteria Glaucoma Intraocular Tumors


Therapy of uveal melanoma A Review.

Cesk Slov Oftalmol 2020 ;1(Ahead of print):1-13

The aim of intraocular melanoma therapy is to achieve local tumor control, reduce the risk of metastasis development, preserve the eyeball and possibly the visual function of the eye. The choice of therapeutic approach requires a comprehensive view and individual approach to each patient with uveal melanoma. Factors considered include local finding (location, tumor size and shape, tumor activity, central visual acuity, intraocular complications), age and the patients overall physical and psychological condition, as well as the patients wishes. Read More

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Intraocular solitary extramedullary plasmacytoma presenting as unilateral anterior and intermediate uveitis preceded by refractory glaucoma.

BMC Ophthalmol 2021 Jan 30;21(1):66. Epub 2021 Jan 30.

University of Sydney, Sydney, Australia.

Background: Solitary extramedullary plasmacytoma (SEP) is a localised proliferation of monoclonal plasma cells involving soft tissue with no or minimal bone marrow involvement and no other systemic evidence of multiple myeloma. Intraocular involvement is exceedingly rare.

Case Presentation: We report a 78-year-old man who was referred with glaucoma in the right eye. Read More

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January 2021

Massive Retinal Gliosis in an Infant Microphthalmic Globe: A Case Report.

Am J Case Rep 2021 Jan 26;22:e929363. Epub 2021 Jan 26.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

BACKGROUND Massive retinal gliosis (MRG) is a rare benign intraocular tumor that results from the proliferation of well-differentiated glial cells in response to long-standing pathological processes, including glaucoma, trauma, chronic inflammation, vascular disorders, and congenital anomalies. This lesion is considered to be nonneoplastic and occurs ≥10 years after the predisposing insult. It usually affects children and can mimic other conditions, including uveal melanomas, vasoproliferative tumors of the retina, astrocytic hamartomas, and retinal hemangioblastomas. Read More

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January 2021

Sturge-Weber syndrome coexisting with polydactyly: a case report.

BMC Ophthalmol 2021 Jan 6;21(1). Epub 2021 Jan 6.

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.

Background: Sturge-Weber syndrome (SWS) is a sporadic congenital disorder, characterized by unilateral facial nevus flammeus associated with ipsilateral glaucoma, choroidal angioma and leptomeningeal hemangiomas. SWS can comorbid with other disorders in some patients, however, there has been no prior described case of SWS and polydactyly occurring in the same patient.

Case Presentation: A 15-year-old girl with diagnosis of SWS presented to our hospital. Read More

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January 2021

Quinazolinones as Competitive Inhibitors of Carbonic Anhydrase-II (Human and Bovine): Synthesis, , Selectivity, and Kinetics Studies.

Front Chem 2020 1;8:598095. Epub 2020 Dec 1.

Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.

Carbonic anhydrase-II (CA-II) is associated with glaucoma, malignant brain tumors, and renal, gastric, and pancreatic carcinomas and is mainly involved in the regulation of the bicarbonate concentration in the eyes. CA-II inhibitors can be used to reduce the intraocular pressure usually associated with glaucoma. In search of potent CA-II inhibitors, a series of quinazolinones derivatives () were synthesized and characterized by IR and NMR spectroscopy. Read More

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December 2020

Iris melanocytoma and secondary glaucoma.

BMJ Case Rep 2020 Dec 13;13(12). Epub 2020 Dec 13.

Ophthalmology, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.

Iris melanocytoma (IM) is a rare variant of iris nevus with distinctive clinical and histopathological features. A 66-year-old woman, with a history of right eye pigmented iris nevus, presented to us with a recent onset of visual acuity decrease in that eye. She had a melanocytic iris lesion with iridocorneal angle invasion, peripheral corneal adhesion, pupil corectopia, sectorial cataract and high intraocular pressure. Read More

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December 2020

Acute elevation of intraocular pressure in patient with hyperlipidemic myeloma.

Cesk Slov Oftalmol 2020 ;76(4):172-180

Purpose: To introduce a rare case of patient with hyperlipidemic myeloma and ocular manifestation in form of masquerade syndrome with acute elevation of intraocular pressure (IOP) and hyperviscous retinopathy.

Results: 55-year-old man with newly diagnosed hyperlipidemic myeloma and hyperviscous syndrome was acutely referred to our glaucoma outpatient clinic due to problems with his left eye: sudden pain, blurred vision, redness of the eye and IOP of 44 mm Hg. We excluded attack of angle closure glaucoma and found presence of whitish material in the anterior chamber and blood obstructing the iridocorneal angle. Read More

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December 2020

Visual outcomes of proton beam therapy for choroidal melanoma at a single institute in the Republic of Korea.

PLoS One 2020 2;15(12):e0242966. Epub 2020 Dec 2.

Proton Therapy Center, Research Institute and Hospital, National Cancer center, Gyeonggi-do, Korea.

We evaluate the ocular effects of proton beam therapy (PBT) in a single institution, in Korea, and identify factors contributing to decreasing visual acuity (VA) after PBT. A total of 40 patients who received PBT for choroidal melanoma (2009‒2016) were reviewed. Dose fractionation was 60‒70 cobalt gray equivalents (CGEs) over five fractions. Read More

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January 2021

Raised intraocular pressure postmaxillectomy and orbital floor reconstruction surgery.

BMJ Case Rep 2020 Nov 4;13(11). Epub 2020 Nov 4.

Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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November 2020

Primary Intrabulbar Neurofibroma.

Authors:
A Furdová P Babál

Cesk Slov Oftalmol 2020 ;76(2):62-67

Purpose: Eye globe enucleation due to other than a malignant tumor is very rare today. Solitary intraocular neurofibroma without other signs of neurofibromatosis is a rare benign tumor and few cases have been reported to date.

Material And Methods: In 10 year interval from Jan 1 2007 to Dec 31 2016 we analyzed non-malignant eye globe enucleations. Read More

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November 2020

Diagnosis and clinical course of ocular ischemic syndrome with retinal vascular abnormalities due to unilateral ocular artery and internal carotid artery stenosis in a child with neurofibromatosis type 1: a case report.

BMC Ophthalmol 2020 Oct 23;20(1):426. Epub 2020 Oct 23.

Department of Ophthalmology, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.

Background: Neurofibromatosis type 1 (NF1) is a hereditary disease that causes neurofibromas generally, but it has been reported to sometimes be associated with various forms of blood vessel stenosis, occlusion and vascular abnormalities of unknown mechanism. However, a symptomatic case with simultaneous ophthalmic artery stenosis and internal carotid artery stenosis is an extremely rare pathogenesis in a child with NF1. In this report, we performed the diagnosis and observation using various imaging modalities for this rare pediatric case. Read More

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October 2020

Therapy of uveal melanoma A Review.

Cesk Slov Oftalmol 2020 ;77(1):1-13

The aim of intraocular melanoma therapy is to achieve local tumor control, reduce the risk of metastasis development, preserve the eyeball and possibly the visual function of the eye. The choice of therapeutic approach requires a comprehensive view and individual approach to each patient with uveal melanoma. Factors considered include local finding (location, tumor size and shape, tumor activity, central visual acuity, intraocular complications), age and the patients overall physical and psychological condition, as well as the patients wishes. Read More

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November 2020

Choroidal melanocytic tumors in dogs: A retrospective study.

Vet Ophthalmol 2020 Nov 21;23(6):987-993. Epub 2020 Oct 21.

College of Veterinary Medicine, Department of Clinical Sciences, Cornell University, Ithaca, NY, USA.

Objective: To describe clinical features of dogs diagnosed with choroidal melanocytic tumors at a veterinary teaching hospital.

Animals Studied: Retrospective case series of 13 dogs (14 melanocytic tumors) with choroidal melanocytic tumors.

Procedures: Medical records of dogs evaluated by the Cornell University ophthalmology service with a clinical diagnosis of a choroidal melanocytic tumor between 2008 and 2020 were reviewed. Read More

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November 2020

Surgical Treatment for SWS Glaucoma: Experience From a Tertiary Referral Pediatric Hospital.

J Glaucoma 2020 12;29(12):1132-1137

Discipline of Ophthalmology, Save Sight Institute.

Precis: Glaucoma associated with Sturge-Weber syndrome (SWS) often requires surgical intervention. Our study shows that trabeculectomy is efficacious in treating this condition.

Purpose: The purpose of this study was to describe the surgical outcomes of glaucoma associated with SWS in children presenting to the tertiary Paediatric Ophthalmology Department at The Children's Hospital at Westmead. Read More

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December 2020

Iris Stromal Cyst in a 6-Month-Old With Rapid Progression to Angle Closure.

J Glaucoma 2020 10;29(10):e113-e115

John Hardesty Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO.

Case Report: A 6-month-old female presented with an iris cyst in the left eye, first identified at age 4 months. The patient was seen by an ophthalmologist at age 6 months and referred for further management. Our examination 2 weeks later demonstrated a 6 mm diameter iris cyst originating from the anterior surface of the inferior iris, occupying the inferior two thirds of the anterior chamber and obscuring the pupil. Read More

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October 2020

A Case of Annular Iris Cyst Diagnosed With the Help of Ultrasound Biomicroscopy.

J Glaucoma 2020 09;29(9):e103-e105

Glaucoma Clinic, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India.

Purpose: To report a case of annular iris cyst presenting as a secondary angle closure managed with Nd:YAG laser iridotomy.

Design: Case report.

Methods: Institutional review board exemption for this case report was obtained from the institutional ethics committee, Aravind eye hospital, Tirunelveli. Read More

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September 2020

[Clinical and Neuroimaging Analysis of 24 Cases of Sturge-Weber Syndrome].

Sichuan Da Xue Xue Bao Yi Xue Ban 2020 Jul;51(4):562-566

Department of Dermatology and Venereology, West China Hospital, Sichuan University, Chengdu 610041, China .

Objective: To analyze the clinical manifestations and neuroimaging characteristics of Sturge-Weber syndrome (SWS), to describe the manifestations of facial port-wine stains (PWS) of SWS, and to explore the screening opinions for SWS.

Methods: A retrospective analysis was performed on the general condition, clinical manifestations, and neuroimaging results of 24 SWS patients from the dermatology department of West China Hospital of Sichuan University between 2017 and 2019. Three different facial PWS distribution methods (traditional anatomical distribution, facial trigeminal nerve distribution, and facial embryological vasculature distribution) in SWS patients were Analysed. Read More

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Uveal amelanotic melanoma in a ragdoll cat.

Authors:
Sarah Jajou

Can Vet J 2020 06;61(6):645-647

Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.

A 13-year-old castrated male ragdoll cat's left eye was evaluated for dyscoria, iridal thickening and color change of 2 years duration, as well as elevated intraocular pressure. The primary lesion seen on ophthalmic examination was a pale pink-white mass observed in the dorsomedial aspect of a diffusely thickened iris. Metastatic workup revealed hepatic and splenic nodules, but cytology was inconclusive. Read More

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CYP1B1 gene: Implications in glaucoma and cancer.

J Cancer 2020 19;11(16):4652-4661. Epub 2020 May 19.

King Abdullah International Medical Research Center (KAIMRC)/ King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), MNGHA, Saudi Arabia.

Glaucoma is a serious disease that can lead to irreversible loss of vision. Patients with primary congenital glaucoma may have elevated intraocular pressure. Hypertension causes damages to intraocular structures and affects the Schlemm's canal, collector channels, trabecular meshwork, and optic nerve's molecular structures. Read More

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Successful treatment of ciliary body medulloepithelioma with intraocular melphalan chemotherapy: a case report.

BMC Ophthalmol 2020 Jun 18;20(1):239. Epub 2020 Jun 18.

Department of Ophthalmology, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, University of Lausanne, Avenue de France 15, 1000, Lausanne 7, Vaud, Switzerland.

Background: Intraocular medulloepithelioma is commonly treated with primary enucleation. Conservative treatment options include brachytherapy, local resection and/or cryotherapy in selected cases. We report for the first time the use of targeted chemotherapy to treat a ciliary body medulloepithelioma with aqueous and vitreous seeding. Read More

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Drug-induced Acute Angle-closure Glaucoma: A Review.

J Curr Glaucoma Pract 2019 Sep-Dec;13(3):104-109

Department of Ophthalmology, UCI Health Gavin Herbert Eye Institute, University of California, Irvine, California, USA.

Aim: Our goal is to review current literature regarding drug-induced acute angle-closure glaucoma (AACG) and provide ophthalmologists and general practitioners with a thorough understanding of inciting medications and treatment pitfalls to be avoided.

Background: Drug-induced AACG is an ophthalmological emergency that ophthalmologists and general practitioners should be familiar with, given its potentially blinding consequences. Common anatomical risk factors for AACG include a shallow anterior chamber depth, short axial length, plateau iris configuration, thick lens, anteriorly positioned lens, and rarely, intraocular tumor. Read More

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Orbital Microscopic Polyangiitis With Secondary Angle Closure Due to Uveal Effusion.

Ophthalmic Plast Reconstr Surg 2021 Jan-Feb 01;37(1):e33-e35

Division of Oculofacial Plastic & Orbital Surgery, Gavin Herbert Eye Institute, University of California Irvine, Irvine, California, U.S.A.

A 63 year-old man presented with 3 weeks of worsening, painless left-sided proptosis, ptosis, and diplopia. Examination of the affected eye revealed normal visual acuity, normal intraocular pressure in the presence of a shallow anterior chamber, grade 1 relative afferent pupillary defect, restricted motility in all directions of gaze, and 6 mm of proptosis. Ultrasound biomicroscopy revealed uveal effusions with anterior rotation of the ciliary body causing appositional angle closure. Read More

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Open angle glaucoma secondary to endogenous cortisone due to pituitary microadenoma in a young patient, a case report.

Arch Soc Esp Oftalmol (Engl Ed) 2020 Jul 15;95(7):353-356. Epub 2020 May 15.

Departamento de Oftalmología, Hospital Puerta de Hierro Majadahonda, Madrid, España; Departamento de Oftalmología, Universidad de Castilla La Mancha, Albacete, España.

Case Report: A 31-year-old male was referred for evaluation after being diagnosed with Cushing syndrome secondary to a pituitary microadenoma. He presented with a reduced visual acuity and high intraocular pressure (IOP) of 48mmHg in both eyes. The examination with biomicroscopy showed normal anterior segment, increased cup to disc ratio, and open angle. Read More

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Neovascular glaucoma in a pediatric patient with neurofibromatosis type 1: a case report.

BMC Ophthalmol 2020 Apr 28;20(1):168. Epub 2020 Apr 28.

Department of ophthalmology, the first hospital affiliated to Army Medical University (Southwest Hospital), Chongqing, 400038, China.

Background: To report a case of a young patient with neurofibromatosis type 1 (NF1).

Methods: Here we review the treatment administered to a 7-year-old NF1 patient with neovascular glaucoma as the primary diagnosis.

Case Presentation: A 7-year-old boy developed visual loss in the right eye associated with periocular pain and ipsilateral headache that had persisted for 1 week. Read More

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Glaucoma as the presenting sign of intraocular tumors: beware of the masquerading sign.

Int Ophthalmol 2020 Jul 20;40(7):1789-1795. Epub 2020 Mar 20.

Ophthalmic Plastic Surgery and Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, 500034, India.

Purpose: To discuss the clinical presentation and management of intraocular tumors masquerading as primary glaucoma or non-tumor-related secondary glaucoma.

Methods: Retrospective chart review.

Results: Ten patients with unsuspected intraocular tumor were referred to glaucoma clinic with a diagnosis of primary glaucoma or non-tumor-related secondary glaucoma. Read More

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Intraoperative intraocular pressure changes during robot-assisted radical prostatectomy: associations with perioperative and clinicopathological factors.

BMC Urol 2020 Mar 12;20(1):26. Epub 2020 Mar 12.

Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachi 1, Niigata, 951-8510, Japan.

Background: Steep Trendelenburg position (ST) during robot-assisted radical prostatectomy (RARP) poses a risk of increase in intraocular pressure (IOP) in men receiving robot-assisted radical prostatectomy (RARP). The aim of the study was to identify clinicopathological factors associated with increased IOP during RARP.

Methods: We prospectively studied 59 consecutive prostate cancer patients without glaucoma. Read More

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Characteristic Cytokine Profiles of Aqueous Humor in Glaucoma Secondary to Sturge-Weber Syndrome.

Front Immunol 2020 28;11. Epub 2020 Jan 28.

Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Patients with Sturge-Weber syndrome (SWS) are susceptible to ocular complications, and among them, glaucoma is one of the most frequent forms. In current study, we utilized multiplex human cytokine antibody array to simultaneously measure the concentration of 40 cytokines in aqueous humor (AH) of patients with SWS-induced glaucoma (SG), or from patients with senile cataract as controls. Compared with the control group, levels of interleukin (IL)-12p40, macrophage inflammatory protein (MIP)-1d, tumor necrosis factor-alpha (TNF-a), IL-5, IL-7, interleukin-6 receptor (IL-6R), and B lymphocyte chemoattractant (BLC) in AH were significantly higher in SG group. Read More

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February 2021

Spontaneous Hyphema from Iris Microhemangiomatosis in an Elderly Patient with Hypertensive Crisis.

Case Rep Ophthalmol 2020 Jan-Apr;11(1):68-72. Epub 2020 Feb 4.

Private Retina Office, University of Buenos Aires, Buenos Aires, Argentina.

Background: Iris microhemangiomatosis is a rare vascular iris tumor, with potential severe complications such as increased intraocular pressure (IOP). We aim to describe a case report of a patient presenting with hyphema secondary to iris microhemangiomatosis triggered by excessive high blood pressure.

Case Presentation: A 74-year-old woman was treated for hypertensive crisis. Read More

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February 2020

Prospective evaluation of visual function in patients with ocular diseases after robot-assisted laparoscopic prostatectomy.

Int J Urol 2020 Apr 11;27(4):307-312. Epub 2020 Feb 11.

Department of Urology, Faculty of Medicine, Kyorin University, Tokyo, Japan.

Objectives: To investigate intraocular pressure and visual function in patients with ocular diseases undergoing robot-assisted laparoscopic prostatectomy.

Methods: We carried out a prospective clinical study of patients undergoing robot-assisted laparoscopic prostatectomy for localized prostate cancer at The University of Tokyo Hospital from December 2015 to March 2017. An ophthalmologist measured intraocular pressure, and carried out visual field testing at 0-2 months before and 7 days after robot-assisted laparoscopic prostatectomy. Read More

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