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Eur J Ophthalmol 2020 May 26:1120672120922453. Epub 2020 May 26.

Ophthalmology Department, Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Purpose: To assess the long-term results of viscotrabeculotomy in infants with primary congenital glaucoma and to compare its outcome with conventional trabeculotomy.

Patients And Methods: A prospective randomized comparative study included infants with primary congenital glaucoma younger than 2 years. Patients were divided into two groups: viscotrabeculotomy group and conventional trabeculotomy group. Read More

J Curr Glaucoma Pract 2019 Sep-Dec;13(3):113-115

Department of Ophthalmology, Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.

Aim: The aim of this report is to explore the risk factors of XEN stent obstruction, suggesting the need for a stricter control of these factors and highlighting areas for further research.

Background: Despite its proven effectiveness and safety profile, XEN gel stents (Allergan Plc, Dublin, Ireland) can become obstructed. The causes and predicting factors for such obstructions still require further research. Read More

J Glaucoma 2020 May 12. Epub 2020 May 12.

St. Peter's Hospital, Albany, New York.

PRéCIS: Combining Trabectome or iStent with phacoemulsification equally reduces IOP and IOP-lowering medication burden during a 24-month follow-up, with a possible advantage to the Trabectome in the early postoperative period.

Purpose: Intra-subject same-surgeon comparison between phacoemulsification combined with Trabectome (Phaco/Trabectome) versus one 1st-generation iStent (Phaco/iStent).

Settings: Private glaucoma and cataract practice. Read More

Graefes Arch Clin Exp Ophthalmol 2020 May 6. Epub 2020 May 6.

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, 1006, Lausanne, Switzerland.

Purpose: To evaluate outcomes of XEN-augmented Baerveldt drainage device implantation in refractory glaucoma and factors predicting surgical success.

Method: All eyes undergoing XEN-augmented Baerveldt for refractory open-angle glaucoma at a tertiary glaucoma centre between January 2016 and November 2017 were retrospectively enrolled. Intraocular pressure (IOP), number of anti-glaucomatous medications and postoperative adverse events (AEs) were analysed for 1 year postoperatively. Read More

J Glaucoma 2020 Apr 13. Epub 2020 Apr 13.

SUNY Upstate Medical University, Department of Ophthalmology, Syracuse, NY, USA.

Purpose: To describe vision threatening complications after micropulse diode transscleral cyclophotocoagulation (MP-TSCPC).

Methods: Retrospective case series. Medical charts of patients that underwent MP-TSCPC and developed visually significant inflammation and hyphema after the procedure are reviewed. Read More

Ocul Oncol Pathol 2020 Mar 3;6(2):115-122. Epub 2019 Sep 3.

Department of Ophthalmology, University Vita-Salute, IRCCS San Raffaele, Milan, Italy.

Introduction: Gamma knife radiosurgery (GKR) has shown promising results in the treatment of intraocular uveal melanoma (UM) in terms of local tumor control. However, GKR is not free from potentially sight-threatening side effects, including cataract, dry eye disease, vitreous hemorrhage, radiation retinopathy (RR), radiation maculopathy (RM), optic neuropathy, and neovascular glaucoma. The aim of this paper is to report our 20-year experience in UM management with GKR focusing on the rate of clinical treatment-induced complications. Read More

Am J Ophthalmol Case Rep 2020 Jun 7;18:100647. Epub 2020 Mar 7.

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

A 42-year-old Hispanic female underwent intravitreal autologous adipose-tissue derived stem cell injection to her left eye in the Dominican Republic for treatment of retinitis pigmentosa associated with Usher Syndrome. Prior to intravitreal injection, the patient's best-corrected-visual-acuity (BCVA) was 1/200. The patient experienced decreased vision gradually over a 3-month period. Read More

Clin Ophthalmol 2020 12;14:795-803. Epub 2020 Mar 12.

Glaucoma Center Montchoisi Clinic, Lausanne, Switzerland.

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma.

Patients And Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma who underwent mDST. Outcome measures were: Surgical Success with 3 criteria - (i) criterion 1 = intraocular pressure (IOP) ≤21 mmHg or reduced by ≥20% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months; (ii) criterion 2 = IOP ≤18 mmHg or reduced by ≥30% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months and (iii) criterion 3 = IOP ≤15 mmHg or reduced by ≥40% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months; IOP Reduction; Use of Anti-glaucoma Medication; Complications; Visual Acuity and Postoperative Interventions. Read More

Int Ophthalmol 2020 Mar 20. Epub 2020 Mar 20.

Ophthalmic Plastic Surgery and Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, 500034, India.

Purpose: To discuss the clinical presentation and management of intraocular tumors masquerading as primary glaucoma or non-tumor-related secondary glaucoma.

Methods: Retrospective chart review.

Results: Ten patients with unsuspected intraocular tumor were referred to glaucoma clinic with a diagnosis of primary glaucoma or non-tumor-related secondary glaucoma. Read More

Sci Rep 2020 Mar 11;10(1):4527. Epub 2020 Mar 11.

Ophthalmology department, Institut du Glaucome, Groupe Hospitalier Paris-Saint-Joseph, 185 rue Raymond Losserand, 75674, Paris, cedex 14, France.

The purpose of this study is to evaluate the efficacy and complications of the XEN implant as a solo procedure or in association with cataract surgery in patients with open angle glaucoma (OAG). All patients who received a XEN implant between June 2017 and June 2018 were included in the study. The primary and secondary outcomes were: the reduction of the intraocular pressure (IOP) at 6 months postoperatively, the decrease of the glaucoma medications 6 months after surgery, the clinical success rate (eyes (%) achieving ≥20% IOP reduction on the same or fewer medications without secondary surgical intervention), the frequency and type of postoperative interventions as well as the complication rate. Read More

Case Rep Ophthalmol 2020 Jan-Apr;11(1):68-72. Epub 2020 Feb 4.

Private Retina Office, University of Buenos Aires, Buenos Aires, Argentina.

Background: Iris microhemangiomatosis is a rare vascular iris tumor, with potential severe complications such as increased intraocular pressure (IOP). We aim to describe a case report of a patient presenting with hyphema secondary to iris microhemangiomatosis triggered by excessive high blood pressure.

Case Presentation: A 74-year-old woman was treated for hypertensive crisis. Read More

Surv Ophthalmol 2020 Feb 11. Epub 2020 Feb 11.

Glaucoma Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Ocular trauma is a significant cause of blindness worldwide, particularly if associated with glaucoma. Direct damage from blunt or penetrating trauma, bleeding, inflammation, lens-related problems, orbital and brain vascular pathologies related to trauma, and chemical injuries may increase intraocular pressure and lead to traumatic glaucoma. Treatment may be as simple as eliminating the underlying cause in some conditions or management can be challenging, depending on the mechanism of damage. Read More

Doc Ophthalmol 2020 Feb 12. Epub 2020 Feb 12.

Chair and Department of Human and Clinical Anatomy, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, Szczecin, 70-111, Poland.

Purpose: To assess the efficacy and safety of the XEN Gel Stent in patients with primary open-angle glaucoma.

Materials And Methods: Twenty eyes of 17 patients (6 males, 11 females) with primary open-angle glaucoma were implanted with XEN Gel Stent. The following data were ascertained in each participant at baseline and at 1, 3, 6, 9 and 12 months following implanting procedure: intraocular pressure, number of anti-glaucoma medications, retinal sensitivity (PS 24/2 w/w), pattern electroretinogram (ISCEV standard), as well as the number of complications. Read More

Medicine (Baltimore) 2020 Feb;99(7):e18637

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, China.

Rationale: To report a case of diode laser transscleral cyclophotocoagulation (DLTSC) for uveitis-glaucoma-hyphema syndrome (UGH).

Patient Concerns: The patient developed UGH on the right eye (OD) after vitrectomy and intraocular lens (IOL) implantation.

Diagnoses: Best corrected visual acuity (BCVA) was HM/50 cm, intraocular pressure (IOP) was 51. Read More

Klin Monbl Augenheilkd 2020 Feb 3. Epub 2020 Feb 3.

Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf.

Background: Various procedures are available for the treatment of advanced glaucoma. We examined the efficacy and safety of fractionated cyclophotocoagulation (CPC) with up to ten laser spots for advanced primary open-angle glaucoma (POAG) and pseudoexfoliation (PEX) glaucoma treated with maximal topical therapy or eye-drop intolerance.

Material Und Methods: This retrospective study evaluated data from 297 eyes with advanced POAG and PEX glaucoma which received 10 applications of CPC between February 2012 and June 2017. Read More

J Fr Ophtalmol 2020 Mar 22;43(3):205-210. Epub 2020 Jan 22.

Service d'ophtalmologie-centre hospitalo-universitaire Charles-Nicolle, 22, boulevard Gambetta, 76031 Rouen, France. Electronic address:

Introduction: Uveitis-Glaucoma-Hyphema syndrome (UGH) is caused by mechanical chafing of anterior segment structures by an intraocular lens, especially an anterior chamber lens. The objective of this study was to characterise the clinical course and risk factors of UGH syndrome at a time when posterior chamber implantation is the gold standard.

Patients And Methods: This was a retrospective study of 30 cases of UGH syndrome managed between January 2014 and September 2018. Read More

Int Ophthalmol 2020 May 20;40(5):1191-1199. Epub 2020 Jan 20.

Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.

Purpose: This study aims to evaluate the efficacy and safety of XEN45 gel stent (Allergan plc, Dublin, Ireland) in East Asian patients with glaucoma.

Methods: A retrospective study of consecutive XEN45 gel stent implantation surgeries with or without concurrent cataract surgery from May 2017 to August 2018 was performed in a single institution. The clinical charts of all cases were reviewed to examine the safety and efficacy of the implant. Read More

Taiwan J Ophthalmol 2019 Oct-Dec;9(4):262-266. Epub 2019 Dec 13.

Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan.

Purpose: The aim is to describe histopathologic observations in eyes enucleated after selective ophthalmic arterial injection (SOAI) of melphalan for retinoblastoma (RB).

Study Design: This is retrospective clinical study.

Patients And Methods: Histopathologic analysis of 14 eyes (13 patients) from May 2008 through January 2015 at Chang Gung Memorial Hospital. Read More

BMC Ophthalmol 2020 Jan 10;20(1):22. Epub 2020 Jan 10.

Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China.

Background: We report a case of uveitis-glaucoma-hyphema (UGH) syndrome in a highly myopic pseudophakic eye with seemingly normal positioning of a two-haptic intraocular lens (IOL).

Case Presentation: The patient was a 61-year-old woman suffering recurrent episodes of blurred vision, floaters, redness, elevated intraocular pressure (IOP), and pain in the right eye following implantation of a sclera-fixed IOL. The symptoms were alleviated by the systemic and topical administration of IOP-lowering and anti-inflammatory medications. Read More

Int Ophthalmol 2020 May 6;40(5):1085-1093. Epub 2020 Jan 6.

Izzet Baysal Training and Research Hospital, Abant Izzet Baysal University, Kılıçarslan Mah. 144. Sk No: 6, Merkez, Bolu, Turkey.

Objectives: To compare successes and complications of XEN GEL Stent implantation and gonioscopy-assisted transluminal trabeculotomy (GATT) surgery in patients with open-angle glaucoma (OAG).

Methods: The multicentre, non-randomized, comparative, interventional, retrospective chart review study included 114 eyes undergoing XEN implantation and 107 eyes undergoing GATT for treatment of OAG. A comprehensive ophthalmic examination consisting of best-corrected LogMAR visual acuity (BCVA), Goldmann Applanation Tonometry, biomicroscopy, fundoscopy and gonioscopy was performed, and then, clinical findings, complications and number of antiglaucomatous medications were noted at the 3-, 6-, 12-, 18- and 24-month postoperative visits. Read More

Graefes Arch Clin Exp Ophthalmol 2020 Feb 7;258(2):387-393. Epub 2019 Dec 7.

Department of Ophthalmology, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.

Background: Canaloplasty is a well-established non-penetrating glaucoma surgery. Unsuccessful outcomes can be enhanced by micro-invasive 360° suture trabeculotomy (360°trabeculotomy), analyzed in this study.

Methods: This retrospective study included twenty eyes of 19 patients, mean age 59. Read More

Graefes Arch Clin Exp Ophthalmol 2020 Feb 30;258(2):379-386. Epub 2019 Nov 30.

Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.

Purpose: The aim of this study was to determine the preliminary efficacy and safety of a novel technique for trabeculotomy for the treatment of primary congenital glaucoma (PCG).

Methods: This retrospective interventional study was conducted on patients with PCG. Pliability test was performed among 5/0 and 6/0 polypropylene sutures and the flexible illuminated microcatheter. Read More

Int J Med Sci 2019 20;16(10):1371-1376. Epub 2019 Sep 20.

Department of Ophthalmology, Jiangsu Province Hospital, Nanjing, Jiangsu Province 210029, China.

To evaluate the efficacy of Ahmed glaucoma valve (AGV) implantation in treating neovascular glaucoma (NVG) and analyze the factors influencing the surgical success rate, a retrospective investigation of 59 NVG patients (66 eyes) who underwent AGV implantation was conducted at Jiangsu Province Hospital, China, from January 2014 to June 2018. Intraocular pressure (IOP), visual acuity, surgical success rates, medications, and complications were monitored at post-operative 1 day, 1 week, 1, 3, 6 and 12 months. Surgical success criteria were defined as 6 mm Hg < IOP < 21 mmHg with or without additional medications. Read More

J Ophthalmol 2019 24;2019:2071506. Epub 2019 Sep 24.

Department of Ophthalmology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.

Purpose: Accumulating studies comparing the efficacy and safety of trabeculectomy and EX-PRESS implantation in open-angle glaucoma (OAG) report inconsistent findings. Thus, we conducted the updated meta-analysis to clarify the issue.

Methods: Randomized controlled trials (RCTs) were selected through search of databases PubMed, Web of Science, Embase, and the Cochrane Library from their inception up until November 2018. Read More

Turk J Ophthalmol 2019 Oct;49(5):277-282

İstanbul Retina Institute, İstanbul, Turkey

Objectives: To compare the outcomes and complications of dislocated intraocular lens (IOL) extraction and secondary iris-claw IOL (ICIOL) implantation in vitrectomized and non-vitrectomized eyes.

Materials And Methods: This retrospective study included 19 vitrectomized eyes and 11 non-vitrectomized eyes that underwent dislocated IOL extraction and secondary anterior chamber ICIOL implantation between June 2014 and September 2017 and had at least one year of follow-up.

Results: There were no significant differences between the groups in terms of demographic data, operative time, baseline anatomic and functional measurements, or postoperative changes in these measurements (all p>0. Read More

Clin Exp Ophthalmol 2020 Jan 20;48(1):127-130. Epub 2019 Oct 20.

Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Ophthalmic Plast Reconstr Surg 2020 Jan/Feb;36(1):e12-e13

Department of Ophthalmology.

Orbital lymphoma can result in rapid loss of vision if not diagnosed and treated in a timely manner. This patient presented with rapid visual loss and on examination had a rubeosis iridis with a hyphema as well as neovascular glaucoma with vitreous hemorrhage. His medical history included systemic diffuse large B-cell lymphoma and a workup ultimately revealed an orbital mass in the body of the optic nerve. Read More

Cureus 2019 Jul 29;11(7):e5270. Epub 2019 Jul 29.

Ophthalmology, Retina Consultants of Austin, Austin, USA.

Purpose Silicone oil a burgeoning adjuvant in the treatment of uveal melanoma where it is used for tissue protection during I-125 brachytherapy. While risk factors in the development of radiation retinopathy (RR) have been identified, treatment modulation for high-risk patients has largely been overlooked. We seek to expand the literature on this subject by reporting outcomes of I-125 brachytherapy with silicone oil in a high-risk population in the community setting. Read More

Int Ophthalmol 2020 Feb 29;40(2):313-323. Epub 2019 Sep 29.

Department of Ophthalmology Hospital Abente y Lago, Complexo Hospitalario Universitario A Coruña, Plaza del Parrote s/n, 15006, A Coruña, Spain.

Purpose: To evaluate the causes of IOL explantation, techniques for secondary IOL implantation, visual outcomes and complications.

Methods: Setting: Department of Ophthalmology Complexo Hospitalario Universitario A Coruña, Spain.

Design: Retrospective study. Read More

Infect Drug Resist 2019 12;12:2487-2493. Epub 2019 Aug 12.

University Eye Clinic Maastricht, Maastricht, the Netherlands.

Purpose: This study aimed to evaluate the outcomes of therapeutic keratoplasty for severe infectious keratitis in Chongqing (Southwest China).

Patients And Methods: The records of 561 eyes that underwent therapeutic keratoplasty for refractory microbial keratitis from 2001 to 2016 were analyzed in this retrospective study. Data included demographic information, microbiological investigations, associated factors, graft size, preoperative status, postoperative complications, and final anatomical outcomes. Read More

Int J Ophthalmol 2019 18;12(8):1290-1297. Epub 2019 Aug 18.

Dunyagoz Hospitals Group, Sultanbeyli 34337, Istanbul, Turkey.

Aim: To evaluate the clinical results, efficacy and safety of Ex-PRESS P200 glaucoma shunt implant in different types of medically uncontrolled glaucoma.

Methods: The study included 31 eyes of 31 patients that were unresponsive to medical antiglaucomatous therapy in whom Ex-PRESS P200 glaucoma shunt implantation was performed. The demographic characteristics of the patients, type of glaucoma, complete ocular examination results, number of antiglaucomatous drugs before and after surgery, early and late complications of surgery, additional surgical and nonsurgical medical interventions, and success rates were investigated from the patients' files, retrospectively. Read More

Clin Ophthalmol 2019 15;13:1235-1246. Epub 2019 Jul 15.

Augencentrum Köln , Köln, Germany.

To evaluate the safety and effectiveness of ab-interno microcatheterization and 360 viscodilation of Schlemm's canal (SC) using the VISCO360 Viscosurgical System in treatment of primary open angle glaucoma (POAG). Surgical center (Augencentrum Köln, Köln, Germany). Retrospective analysis of 106 eyes from 71 consecutive patients. Read More

Semin Ophthalmol 2019 7;34(7-8):488-496. Epub 2019 Aug 7.

Saskatoon Retinal Consultants, Department of Ophthalmology, University of Saskatchewan, Saskatoon, Canada.

. Implantation of sutureless, scleral-fixated posterior chamber intraocular lenses (SSFIOL) is a promising option in the surgical management of patients unable to undergo standard cataract surgery due to insufficient capsular support. The purpose of this study was to describe the indications, visual outcomes and complications of SSFIOL implantation. Read More

Asia Pac J Ophthalmol (Phila) 2019 Jul-Aug;8(4):308-313

Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Purpose: The aim of the current study was to compare visco-trabeculotomy (VT) with standard trabeculectomy with mitomycin C (Trab-MMC) in the treatment of quiescent neovascular glaucoma (NVG).

Methods: The study was conducted on 51 eyes of 51 patients presenting with NVG and treated at an Ophthalmic Center in Egypt between March 2014 and April 2017. All study eyes were subjected to a standard protocol of intravitreal injection of ranibizumab followed by panretinal photocoagulation. Read More

Cutan Ocul Toxicol 2019 Dec 12;38(4):395-400. Epub 2019 Aug 12.

Ministry of Health, Haydarpasa Numune Training and Research Hospital , İstanbul , Turkey.

To evaluate the efficacy of 5-fluorouracil (5-FU) needling of encapsulated blebs (EBs) after Ahmed glaucoma valve (AGV) implantation in patients with medically uncontrolled secondary glaucoma. Thirty-eight eyes of 37 patients who underwent AGV implantation due to secondary glaucoma with EB were recruited in this retrospective non-randomized study. 5-FU needling (0. Read More

Can J Ophthalmol 2019 08 26;54(4):445-450. Epub 2018 Nov 26.

Oakland University William Beaumont School of Medicine, Department of Ophthalmology, Beaumont Health System, Royal Oak, Mich; Associates in Ophthalmology, Farmington Hills, Mich.. Electronic address:

Objective: To propose a late-onset mechanism for uveitis-glaucoma-hyphema (UGH) syndrome caused by Soemmering ring cataract (SRC) and describe surgical outcomes.

Design: Retrospective interventional case series.

Participants: Patients developing UGH from anterior displacement of a haptic from a SRC. Read More

Acta Ophthalmol 2020 Feb 25;98(1):e81-e87. Epub 2019 Jul 25.

Department of Ophthalmology and Visual Science, Hiroshima University Graduate School of Biomedical Sciences, Minami-ku Hiroshima, Japan.

Purpose: To examine the efficacy and safety of current trabeculectomy with mitomycin C in Japan for glaucomatous eyes with low intraocular pressure (IOP).

Methods: Two hundred ninety-four eyes of 294 patients with IOP ≤21 mmHg before surgery were studied; all patients were participants in the Collaborative Bleb-related Infection Incidence and Treatment Study (CBIITS), a multicentre, prospective, cohort study conducted at 34 ophthalmological institutions throughout Japan. All eyes had an intraocular pressure ≤ 21 mmHg and had undergone trabeculectomy alone or phacotrabeculectomy. Read More

J Glaucoma 2019 Sep;28(9):823-833

Department of Medicine, University of Udine, Udine, Italy.

Purpose: The purpose of this study was to conduct a meta-analysis on the efficacy and safety of trabeculectomy (TE) and nonpenetrating glaucoma surgery (NPGS) techniques in patients with primary open-angle glaucoma, pseudoexfoliation glaucoma, pigmentary glaucoma, and normal-tension glaucoma.

Methods: All studies were identified by searching electronic sources (PubMed, Medline, Scopus, and Embase) until February 5, 2018. Primary outcome was mean intraocular pressure (IOP) reduction at 6, 12, and 24 months. Read More

J Glaucoma 2019 Oct;28(10):e159-e161

Department of Ophthalmology, Henry Ford Hospital, Detroit, MI.

Purpose: To report a case of a 69-year-old patient who developed uveitis-glaucoma-hyphema syndrome (UGH) after an uneventful EX-PRESS mini shunt surgery for advanced primary open-angle glaucoma and to discuss management options and clinical implications. UGH syndrome is a rare, but serious complication usually described after cataract surgery. It is often described in anterior chamber intraocular lenses, sulcus lenses, and malpositioned or subluxed lenses resulting in chafing of the lens-iris interface. Read More

J Glaucoma 2019 Sep;28(9):811-817

Department of Ophthalmology, Ortenau Klinikum Offenburg-Gengenbach, Offenburg.

PRéCIS:: Significant intraocular pressure (IOP) reduction was achieved using a novel suture-probe canaloplasty (SPCP) procedure in patients with glaucoma. The effect and low rate of surgical complications were comparable with those of iTrack canaloplasty.

Purpose: Ab externo canaloplasty using the iTrack microcatheter has been established as a safe surgical procedure to treat open-angle glaucoma. Read More

Medicine (Baltimore) 2019 Jun;98(26):e16215

Department of Ophthalmology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Rationale: Optic disk hemorrhage has been closely correlated with glaucoma for its development and progression. Phacoemulsification surgery results in large intraocular pressure (IOP) fluctuation. We report a case of optic disk hemorrhage and consequently progressive vitreous hemorrhage after an unsuccessful phacoemulsification surgery in an advanced normal tension glaucoma (NTG) patient. Read More

J Glaucoma 2019 Sep;28(9):803-807

Department of Ophthalmology & Visual Sciences, University of Michigan, Ann Arbor, MI.

Precis: Gonioscopy-assisted transluminal trabeculotomy (GATT) is a novel technique that lowers intraocular pressure (IOP) by fracturing the trabecular meshwork. In this retrospective chart review, GATT was found to be effective at lowering the intraocular pressure for steroid-induced glaucoma (SIG).

Purpose: GATT is a novel microinvasive glaucoma surgery that builds on traditional trabeculotomy techniques to decrease the proximal resistance of conventional outflow, and it is proposed to be an effective surgical treatment for SIG. Read More

Sultan Qaboos Univ Med J 2019 Feb 30;19(1):e63-e67. Epub 2019 May 30.

Department of Ophthalmology, Universidad Industrial de Santander, Bucaramanga, Santander, Colombia.

Massive hyphaema presentation after a laser iridotomy is very rare. We report a 63-year-old man with ischaemic heart disease on dual antiplatelet therapy (aspirin plus ticagrelor) who was diagnosed as a primary angle-closure suspect and was to undergo a neodymium-doped yttrium aluminium garnet laser iridotomy at Centro Oftalmológico Virgilio Galvis, Floridablanca, Colombia in 2016. While performing the iridotomy in the left eye, active bleeding occurred that finally filled approximately 75% of the anterior chamber. Read More

Zhonghua Yan Ke Za Zhi 2019 Jun;55(6):448-453

The Eye Hospital of Wenzhou Medical University, Wenzhou 325000, China (Meng Jingya is now working at Anyang Eye Hospital, Henan Province, Anyang 455000, China).

To evaluate the preliminary efficacy and safety of penetrating canaloplasty for treating primary angle-closure glaucoma (PACG). It is a prospective interventional case series study. Twenty-two patients (24 eyes) with PACG were treated with penetrating canaloplasty (video attached) at the Eye Hospital of Wenzhou Medical University from June 2015 to August 2018. Read More

Eur J Ophthalmol 2019 Jun 12:1120672119856515. Epub 2019 Jun 12.

2 Department of Paediatric Haematology, Meram School of Medicine, Necmettin Erbakan University, Konya, Turkey.

Purpose: To describe a case of traumatic hyphema in a patient with severe hemophilia A.

Case: We present a case of a 16-year-old boy with severe hemophilia A who presented to our ophthalmology department with total hyphema and elevated intraocular pressure 3 days after a history of blunt ocular trauma on his right eye. Due to the persistent intraocular pressure elevation and total hyphema despite medical intervention, an early anterior chamber washout was performed with the replacement of factor VIII preoperatively and postoperatively. Read More

BMC Ophthalmol 2019 Jun 11;19(1):128. Epub 2019 Jun 11.

Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Clinical College of Ophthalmology, Tianjin Medical University, No.4 Gansu Rd, Heping District, Tianjin, 300020, China.

Background: The aim of the present study was to evaluate the efficacy and safety of intravitreal conbercept combined with trabeculectomy and panretinal photocoagulation for neovascular glaucoma (NVG).

Methods: Fifty patients (54 eyes) with NVG were included in this prospective study. Fifty-two eyes initially underwent intravitreal conbercept (0. Read More

Indian J Ophthalmol 2019 06;67(6):785-787

Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Purpose: To study the clinicopathological findings of Persistent Fetal Vasculature (PFV) in patients with congenital cataract and PFV.

Methods: Six eyes with anterior or combined PFV with cataract underwent phacoaspiration with primary posterior capsulotomy with anterior vitrectomy with intraocular lens implantation followed by histopathological evaluation of the PFV stalk and membrane.

Results: Four and two patients had combined and anterior PFV respectively. Read More

J Ophthalmic Vis Res 2019 Apr-Jun;14(2):215-218

Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, USA.

Purpose: To report a case of uveitis-glaucoma-hyphema syndrome (UGHS) secondary to a large capsulorhexis with an intracaspular intraocular lens (IOL) managed with IOL exchange and gonioscopy assisted transluminal trabeculotomy (GATT).

Case Report: A 73-year-old male patient presented with UGHS of the right eye in the setting of an intracapsular single-piece acrylic IOL with circumferential optic and partial haptics exposure due to a large capsulorhexis. In lieu of the patient's uncomplicated surgical history, subtle symptoms, and clinical findings, the diagnosis and referral was delayed until intraocular pressure reached a peak of 50 mmHg with recurrent anterior chamber cells. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Aug 16;257(8):1741-1750. Epub 2019 May 16.

Ophthalmology Department, Hospital General Universitario de Alicante, Alicante, Pintor Baeza, 11, 03010, Alicante, Spain.

Purpose: To compare the efficacy and safety of the XEN45 implant with that of trabeculectomy (TRAB), either alone or in combination with phacoemulsification (PHACO), in patients with open-angle glaucoma (OAG).

Methods: Retrospective, single-center and comparative study conducted on OAG patients. Patients were divided into four groups: group 1 (XEN alone); group 2 (XEN+PHACO); group 3 (TRAB alone); group 4 (TRAB+PHACO). Read More

Ophthalmologe 2019 Dec;116(12):1200-1206

Klinik für Augenheilkunde, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Background: Sutured scleral fixation of an artificial posterior chamber lens is a frequently used method for the treatment of eyes with poor or absent capsular support; however, the complication profile is often considered unfavorable.

Objective: To analyze the postoperative complication profile.

Methods: In this monocentric and retrospective analysis of a consecutive case series of patients with standardized sutured scleral fixation of a posterior chamber lens between 2007 and 2017, the documented complications were categorized as a permanent threat to visual acuity, such as endophthalmitis, choroidal hemorrhage, retinal detachment and clinically relevant but without a permanent threat to visual acuity, such as hemorrhage and hypotension. Read More