Search Our Scientific Publications & Authors

J Med Econ 2019 Jan 19. Epub 2019 Jan 19.

e Goeree Consulting Ltd , Hamilton , ON , Canada.

Objectives: To estimate the cost-utility of two trabecular micro-bypass stents (TBS) implantation versus standard of care (SOC) in patients with mild-to-moderate open-angle glaucoma (OAG) in the Canadian healthcare setting.

Methods: The deterioration in visual field (VF) defect over a 15-year time horizon was tracked using a Markov model with Hodapp-Parrish-Anderson stages of glaucoma (mild, moderate, advanced, severe/blind) and death as health states. Meta-analyses of randomized clinical trials were conducted to estimate the pooled reduction in intraocular pressure (IOP) and medication use due to TBS and SOC. Read More

BMC Ophthalmol 2019 Jan 10;19(1):14. Epub 2019 Jan 10.

Department of Ophthalmology, University Medical Center Schleswig-Holstein, Arnold-Heller Strasse 3, Haus 25, D-24105, Kiel, Germany.

Background: To evaluate long-term results of eyes with glaucoma drainage device (GDD).

Methods: We retrospectively reviewed medical records of all patients who underwent GDD placement at our institution between 2001 and 2014. A total of 110 eyes of 90 patients were studied. Read More

J Glaucoma 2019 Jan 8. Epub 2019 Jan 8.

Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles.

Purpose: To evaluate the outcomes of autologous limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness donor corneal allograft in management of tube erosion of glaucoma drainage device (GDD).

Methods: Consecutive patients who had undergone a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft were reviewed. Primary outcome was surgical success of coverage of the exposed tube without complications or additional surgeries. Read More

J Glaucoma 2018 Dec 24. Epub 2018 Dec 24.

Royal Blackburn and Burnley General Teaching Hospitals, East Lancashire Hospitals NHS Trust, Lancashire, UK.

A 78 old male with angle closure glaucoma and on treatment with oral anticoagulants, underwent phacoemulsification. An early acute suprachoroidal hemorrhage (SCH) occurred and the surgical wound was rapidly sutured without complete soft lens matter (SLM) removal, nor insertion of intraocular lens (IOL). The SCH was managed conservatively and it resolved in 5 weeks; the intraocular pressure was 35▒mm Hg despite maximal medical treatment. Read More

Clin Ophthalmol 2018 7;12:2545-2552. Epub 2018 Dec 7.

Department of Ophthalmology, University of Hong Kong, Hong Kong, People's Republic of China,

Purpose: This is a pilot study to compare the effectiveness and safety of diode laser transscleral cyclophotocoagulation (TSCP) with the Ahmed glaucoma valve (AGV) in the management of neovascular glaucoma (NVG).

Methods: Eyes with NVG and an IOP greater than 21 mmHg on maximal medications, without previous glaucoma surgery or cyclodestruction, were randomized for either TSCP or AGV implantation. These eyes were followed for at least 6 months and analyzed with respect to their visual outcome, IOP, number of glaucoma medications required, and related complications. Read More

Clin Ophthalmol 2018 28;12:2439-2449. Epub 2018 Nov 28.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan,

Purpose: To describe the 1-year surgical outcomes of both Baerveldt glaucoma implant (BGI) and the Ahmed glaucoma valve (AGV) implant with pars plana tube insertion in Japanese eyes with neovascular glaucoma (NVG).

Patients And Methods: This was a retrospective study of 21 eyes of 18 patients who had undergone BGI (10 eyes) or AGV (11 eyes) implantation. The 1-year surgical outcomes in the two groups were compared. Read More

Klin Monbl Augenheilkd 2018 Dec 19;235(12):1360-1365. Epub 2018 Dec 19.

Institut für ImplantatTechnologie und Biomaterialien e. V., Rostock-Warnemünde.

Purpose: Evaluation of the long-term efficiency of MIGS implants is still challenging, due to the lack of standardized clinical studies of stand-alone procedures. Moreover, the different mechanisms of the various glaucoma drainage devices are not adequately considered. The current study focusses on the development of a method for oculopression to evaluate the efficiency of glaucoma drainage devices. Read More

Korean J Ophthalmol 2018 Dec;32(6):523-524

Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, Korea.

Clin Exp Ophthalmol 2018 Dec 13. Epub 2018 Dec 13.

South Australian Institute of Ophthalmology, The University of Adelaide, South Australia, Australia.

Importance: The demand for glaucoma care is projected to increase significantly with the ageing population.

Background: To characterise trends in Australian practice patterns for glaucoma management over the 15-year period between 2003 and 2017.

Design: Retrospective audit. Read More

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Netherlands Institute for Innovative Ocular Surgery (NIIOS), Rotterdam, The Netherlands; Melles Cornea Clinic Rotterdam, The Netherlands; Amnitrans Eye Bank Rotterdam, The Netherlands; NIIOS-USA, San Diego, USA. Electronic address:

Purpose: To evaluate the feasibility and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with a glaucoma drainage device (GDD).

Design: Retrospective, interventional case series.

Methods: Clinical outcomes of 23 DMEK procedures for bullous keratopathy (52%), failed previous transplant (39%) or Fuchs endothelial corneal dystrophy (9%) in 20 eyes (19 patients) with a GDD were retrospectively analyzed at two tertiary referral centers. Read More

Vestn Oftalmol 2018 ;134(5. Vyp. 2):244-249

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

The XEN-45 drainage implant is a hypotensive device made of hydrophilic gelatin and stabilized by glutaraldehyde. The implant is designed for modern Microinvasive Glaucoma Surgery (MIGS). Being installed ab interno, the stent drains aqueous fluid from the anterior chamber into the subconjunctival space. Read More

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):498-500

Department of Ophthalmology, University of Virginia, School of Medicine, Charlottesville, Virginia, USA.

The modern glaucoma drainage implant era was initiated with implantation of a plate posterior to the limbus connected to the anterior chamber by a long silicone tube. Non-restrictive (Molteno and Baerveldt implants) and flow-restrictive (Ahmed Glaucoma Valve) implants were developed. With increased clinical experience, variables influencing success and failure of glaucoma drainage implant surgery were better understood. Read More

Eur J Ophthalmol 2018 Nov 26:1120672118815066. Epub 2018 Nov 26.

Hospital Sao Geraldo, HC-Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Objective:: To assess the feasibility of a novel surgical technique in painful blind eyes.

Design:: A prospective safety study conducted at the Federal University of Minas Gerais, Brazil.

Participants/samples:: A total of 15 end-stage glaucomatous eyes without light perception vision. Read More

Indian J Ophthalmol 2018 Dec;66(12):1820-1824

Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To evaluate the outcome of rhegmatogenous retinal detachment (RRD) surgery in eyes with preplaced glaucoma drainage device (GDD) with respect to intraocular pressure (IOP) control as well as success of retinal detachment (RD) surgery.

Methods: It is a retrospective case series. The case records of patients who underwent RD surgery after GDD implantation from 2000 to 2014 were screened. Read More

Surv Ophthalmol 2018 Nov 3. Epub 2018 Nov 3.

New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA; Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Insertion of glaucoma drainage devices has become a mainstay in the surgical management of multiple forms of glaucoma, and the indications for this procedure continue to expand. A unique clinical challenge in the postoperative care of these devices is the hypertensive phase, a period of postoperative intraocular pressure elevation in the first three months after surgery. We discuss the influence of a variety of factors on the development of the hypertensive phase after glaucoma drainage implantation, including type of device, device material, and device surface area. Read More

Indian J Ophthalmol 2018 11;66(11):1585-1586

Senior Glaucoma and Cataract Specialist Centre for Sight, Banjara Hills; Neoretina Eyecare Institute, Abids; Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.

Indian J Ophthalmol 2018 Nov;66(11):1580-1585

Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Purpose: To study the efficacy of the Aurolab aqueous drainage implant (AADI) compared to Ahmed glaucoma valve (AGV) in patients with refractory glaucoma.

Methods: This was a prospective, randomized controlled trial. Thirty-eight adult patients (>18 years) scheduled for a glaucoma drainage device (GDD) were randomized into two groups to receive either AGV or AADI. Read More

BMJ Case Rep 2018 Oct 21;2018. Epub 2018 Oct 21.

Department of Ophthalmology, Hospital de Santa Maria, Lisboa, Portugal.

A 51-year-old woman was referred with uncontrolled intraocular pressure (IOP) despite maximal medical IOP-lowering therapy. Her background included several failed glaucoma filtering surgeries, including aqueous drainage devices. Considering the need to perform surgery in a patient with both scarred conjunctiva and corneal endothelial deficiency, a surgical technique combining cornea-friendly XEN stent connected to a large-plate Baerveldt glaucoma implant was undertaken. Read More

Can J Ophthalmol 2018 Oct 7;53(5):510-517. Epub 2018 May 7.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.

Objective: To report and analyze the clinical outcomes of the first 250 cases of Descemet membrane endothelial keratoplasty (DMEK).

Methods: A retrospective case series was conducted on the first 250 DMEK cases. The cohort included eyes with previous trabeculectomy, pre-existing glaucoma drainage device, and previous vitrectomy. Read More

J Glaucoma 2019 Jan;28(1):56-60

Department of Ophthalmology, Hospital Santa Maria.

Purpose: The XEN gel stent is a minimally invasive surgical device aimed at creating a subconjunctival drainage of aqueous humor, thereby reducing intraocular pressure (IOP). Being a novel device, doubts remain with regard to the efficacy and safety of its implantation in the early stage of new users. This paper illustrates the XEN implantation learning curve, assessed through several surgeons of different expertise. Read More

Korean J Ophthalmol 2018 Oct;32(5):400-408

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: To evaluate the outcome of Ahmed glaucoma valve (AGV) implantation in eyes with refractory secondary glaucoma following pars plana vitrectomy (PPV) and the associated prognostic factors.

Methods: A total of 146 eyes in 146 patients who underwent AGV implantation after PPV (followed up for ≥1 year) were included. AGV implantation was considered successful when the intraocular pressure (IOP) was 6 to 21 mmHg regardless of using IOP-lowering medication. Read More

Korean J Ophthalmol 2018 Oct;32(5):391-399

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Purpose: To evaluate the long-term effects of early postoperative intraocular pressure (IOP) after Ahmed glaucoma valve (AGV) implantation on long-term surgical outcomes.

Methods: This retrospective, non-randomized study included 100 eyes of 100 patients who underwent AGV surgery. We divided the enrolled patients into four groups according to the presence of transient hypotony within the first postoperative week or the presence of a hypertensive phase during the first three postoperative months. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Jan 11;257(1):143-151. Epub 2018 Oct 11.

Department of Ophthalmology, Erasmus Medical Center, 's Gravendijkwal 230, 3000 CA, Rotterdam, The Netherlands.

Purpose: To assess the efficacy of glaucoma drainage devices (GDD) in uveitic glaucoma and non-uveitic glaucoma, and to perform a meta-analysis of previously published results to compare with our data.

Methods: Retrospective case-control study, in which all eyes that underwent GDD surgery were included from 2015 onwards. Cases were defined as patients with uveitic glaucoma. Read More

Acta Ophthalmol 2018 Oct 4. Epub 2018 Oct 4.

Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Purpose: To determine the cost (loss of visual function associated with the procedure) and benefit (long-term preservation of the visual field) of glaucoma surgery.

Methods: We included 100 patients who underwent glaucoma surgery (Baerveldt glaucoma implant [BGI], n = 61; trabeculectomy [TE], n = 39). Preoperatively, the median (interquartile range [IQR]) standard automated perimetry mean deviation (MD) was -12 (-16 to -6) dB. Read More

BMC Ophthalmol 2018 Sep 14;18(Suppl 1):222. Epub 2018 Sep 14.

Western Eye Hospital, London, UK.

Background: The surgical management of patients with uncontrolled glaucoma and scleroderma is challenging, as the hostile ocular surface poses a challenge to surgery. A serious complication is tube erosion, with the risk of subsequent endophthalmitis. Here, we present a novel technique of harvesting autologous tissue to successfully manage recurrent tube extrusion. Read More

Medwave 2018 Sep 7;18(5):e7239. Epub 2018 Sep 7.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Oftalmología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Av. Diagonal Paraguay 476, Santiago, Chile.

Introduction: Aqueous shunt has emerged as an alternative technique to trabeculectomy, considered the standard for glaucoma surgery. Currently, it is mainly indicated after failure of trabeculectomy or in glaucoma with high risk of failure. The Ahmed valve and the Baerveldt implant are the most commonly used aqueous shunts. Read More

Retina 2018 Sep 17. Epub 2018 Sep 17.

Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio.

Purpose: To investigate the effect of serial anterior chamber (AC) paracenteses in eyes with sustained elevations of intraocular pressure (IOP) in the setting of repeated intravitreal injections (IVI) of anti-vascular endothelial growth factor medications.

Methods: This is a retrospective records review of patients undergoing IVI of anti-vascular endothelial growth factor medication (bevacizumab, ranubizumab, or aflibercept), who demonstrated a sustained elevation of preinjection IOP and also received AC paracentesis immediately after IVI on at least three consecutive visits. Changes in preinjection IOP and cup-to-disk (C:D) ratio were compared before and after the initiation of IVI and before and after the introduction of AC paracenteses with each subsequent IVI. Read More

Transl Vis Sci Technol 2018 Sep 13;7(5). Epub 2018 Sep 13.

Rotterdam Eye Hospital, Glaucoma Department, Schiedamse Vest 180 3011BH Rotterdam, The Netherlands.

Purpose: The purpose of this study was to quantify any diplopia and motility changes after the implantation of a Baerveldt glaucoma implant (BGI) or after trabeculectomy (TE).

Methods: We analyzed 51 patients with a BGI and 52 patients with a TE from a prospective cohort study. To quantify any diplopia, we asked patients about the presence of diplopia at 1 year after surgery. Read More

Cornea 2018 Nov;37 Suppl 1:S78-S85

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

Purpose: To restore vision in complex eyes with coexisting anterior and posterior segment problems, combined corneal transplantation (penetrating keratoplasty [PK] or Descemet-stripping automated endothelial keratoplasty [DSAEK]), pars plana vitrectomy (PPV), and/or flanged intrascleral intraocular lens (IOL) fixation, designated vitreocorneal surgery are performed. In this study, we evaluated the usefulness of vitreocorneal surgery for eyes with complex comorbidities.

Methods: Thirteen consecutive eyes in 13 patients with coexisting corneal pathology (ie, corneal scarring, bullous keratoplasty, corneal laceration) and posterior segment pathology (ie, aphakia without capsular support, retinal detachment, intravitreal foreign body) underwent vitreocorneal surgery. Read More

Ocul Immunol Inflamm 2018 Sep 13:1-8. Epub 2018 Sep 13.

a Manchester Royal Eye Hospital , Manchester University NHS Foundation Trust , Manchester , UK.

Purpose: This study investigated the efficacy and safety of Baerveldt glaucoma implants (BGI) in adults with uveitic glaucoma (UG) at the Manchester Uveitis Clinic.

Methods: This was a retrospective study of 42 patients with UG who underwent BGI implantation between 2006 and 2015. Primary outcome measures were intraocular pressure (IOP) reduction and number of medications at 5-year follow-up. Read More

BMC Ophthalmol 2018 Sep 10;18(1):243. Epub 2018 Sep 10.

Department of Ophthalmology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.

Background: To compare trabeculectomy and EX-PRESS device implantation procedures for treating glaucoma and evaluate changes in corneal endothelial cell density (CECD).

Methods: This study prospectively evaluated changes in the CECD in 60 eyes of 60 patients who underwent trabeculectomy and 50 eyes of 45 patients who underwent EX-PRESS device implantation. Baseline patient data recorded included age at surgery, sex, type of glaucoma medications, and lens status. Read More

J Glaucoma 2018 Oct;27(10):910-913

Glaucoma Service, Department of Ophthalmology, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Purpose: To investigate the safety and long-term results of conjunctival pedicle graft (CPG) technique for revision of exposed glaucoma drainage device (GDD).

Design: Retrospective noncomparative case series.

Patients And Methods: All patients with exposed GDD between 2011 and 2016 who underwent tube revision with CPG were included. Read More

J Glaucoma 2018 Dec;27(12):1145-1150

Department of Ophthalmology, Duke University.

Purpose: The purpose of this study was to compare early postoperative outcomes of patients who underwent Baerveldt 350-mm aqueous drainage device (Abbott Medical Optics Inc., Santa Ana, CA) implantation with and without 7-0 polyglactin (vicryl) suture placement through tube fenestration to serve as a stenting wick.

Methods: Patients were identified by a retrospective review of the electronic medical records of one attending surgeon's Baerveldt implantation (LWH) conducted by searching the Current Procedural Terminology code "placement of aqueous shunt. Read More

Graefes Arch Clin Exp Ophthalmol 2018 Nov 31;256(11):2191-2200. Epub 2018 Aug 31.

Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

Purpose: We compared the outcomes of Baerveldt glaucoma implant (BGI) surgery between vitreous cavity and anterior chamber insertion.

Methods: We retrospectively analyzed a total of 105 consecutive eyes that underwent BGI surgery and were followed up for ≥ 12 months. BGI surgery was performed via the anterior chamber (AC group 48 eyes) or the pars plana into the vitreous cavity (VC group 57 eyes). Read More

BMC Ophthalmol 2018 Aug 31;18(1):226. Epub 2018 Aug 31.

FEBO, Dunyagoz Hospital, Istanbul, Turkey.

Background: To describe a new technique and present its long-term outcome for prevention of Ahmed glaucoma valve (AGV) tube exposure in patients with refractory glaucoma.

Methods: Twenty-seven eyes of 24 patients (mean age, 50 years; age range, 16-78 years; 8 females, 16 males) with refractory glaucoma who had the AGV implant were retrospectively reviewed. For AGV implantation, a long scleral flap combined with Tenon advancement and duplication was used. Read More

BMC Ophthalmol 2018 Aug 29;18(1):212. Epub 2018 Aug 29.

Department of Ophthalmology, Tongde Hospital of Zhejiang Province, 234 Gucui Road, Hangzhou, 310012, China.

Background: The purpose of this study was to compare the efficacy and safety of pars plana glaucoma drainage device (PP GDD) with anterior chamber glaucoma drainage device (AC GDD) for the treatment of glaucoma.

Methods: We comprehensively searched three databases, including PubMed, EMBASE, and the Cochrane Library databases, selecting the relevant studies. The continuous variables, namely, intraocular pressure (IOP) and glaucoma medications, were pooled by the weighted mean differences (WMDs), and the dichotomous outcomes, including corneal failure incidence and overall complications incidence, were pooled by the odds ratio (ORs). Read More

Clin Ophthalmol 2018 17;12:1479-1486. Epub 2018 Aug 17.

Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand,

Background: The aim of the study was to evaluate factors related to hypertensive phase (HP) after glaucoma drainage device (GDD) implantation.

Patients And Methods: Retrospective charts review of glaucoma patients who underwent GDD implantation and completed 12 months of follow-up at King Chulalongkorn Memorial Hospital since 2004 was performed. Patients were divided into two groups according to the presence or absence of HP. Read More

J AAPOS 2018 Dec 23;22(6):475-477.e1. Epub 2018 Aug 23.

Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon; Childhood Glaucoma Center, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon. Electronic address:

Glaucoma drainage devices are commonly used in the surgical treatment of children with glaucoma. We report a case of unusually large reservoir formation causing proptosis, exposure keratopathy, and motility deficits. This case highlights the importance of B-scan and axial length measurements in differentiating proptosis from buphthalmos in children with glaucoma. Read More

Am J Ophthalmol Case Rep 2018 Dec 18;12:32-35. Epub 2018 Aug 18.

Department of Ophthalmology, Université de Montréal, Montreal, QC, Canada.

Purpose: To report the first successfully treated case of recurrent tube exposure in a patient with the Boston Keratoprosthesis type 1 with a collagen matrix patch graft (Ologen).

Observations: A 50 year-old female with a Boston Keratoprosthesis type 1 and a history of Axenfeld-Reiger syndrome presents to our department with recurrent glaucoma drainage device exposure in her left eye. After failed spontaneous closure with topical antibiotics and lubricants, she undergoes tube exposure repair using an Ologen patch graft. Read More

Graefes Arch Clin Exp Ophthalmol 2018 Nov 21;256(11):2181-2189. Epub 2018 Aug 21.

Ophthalmology Department, Hawke's Bay Fallen Soldiers' Memorial Hospital, Hastings, New Zealand.

Purpose: To produce an economic comparison of the iStent ab interno trabecular microbypass implant accompanying cataract surgery and selective laser trabeculoplasty (SLT) as first-line treatment versus topical medications for open-angle glaucoma in New Zealand in 2016.

Methods: The current annual costs of 19 available fully subsidised topical glaucoma medications by Pharmaceutical Management Agency (Pharmac) in 2016 were identified. Adjustments for pharmacist prescribing charges and previously described wastage levels were applied. Read More

Am J Ophthalmol Case Rep 2018 Sep 21;11:124-127. Epub 2018 Jun 21.

Department of Ophthalmology and Vision Science, University of California at Davis, Sacramento, CA, USA.

Purpose: To report a case of metastatic intraocular medulloepithelioma successfully treated with neoadjuvant chemotherapy, superficial parotidectomy, and enucleation.

Observations: A 5-year-old male with history of cataract surgery, glaucoma drainage device, endocyclophotocoagulation, scleral patch grafting, and chronic posterior "inflammation" in a blind left eye presented with a rapidly enlarging painful mass under the left upper eyelid. Biopsy of the conjunctival mass and fine needle aspiration of an enlarged preauricular lymph node revealed medulloepithelioma, which was also seen in the left parotid gland on positron emission tomography (PET) scan. Read More

Indian J Ophthalmol 2018 09;66(9):1284

Department of Glaucoma, Centre for Sight, Safadarjung Enclave, New Delhi, India.

Indian J Ophthalmol 2018 09;66(9):1278-1283

Centre for Sight, Banjara Hills, Hyderabad, India.

Purpose: The purpose of the study is to report the outcomes of simultaneous cataract extraction (CE) and a new nonvalved glaucoma drainage device (GDD), Aurolab Aqueous Drainage Implant (AADI), in eyes with cataract and refractory glaucoma.

Methods: This was a non-comparative, interventional, retrospective study. Consecutive patients who underwent AADI together with phacoemulsification from June-2015 to January-2017 by a single fellowship trained glaucoma surgeon with documented 3-months of follow-up were included. Read More

J Cataract Refract Surg 2018 Oct 11;44(10):1284-1290. Epub 2018 Aug 11.

From the Department of Cornea and Refractive Surgery (Cabral-Macias, García-De la Rosa, Rodríguez-Matilde, Vela-Barrera, Ramirez-Miranda, Graue-Hernandez, Graue-Hernandez) and the Department of Glaucoma (Ledesma-Gil), Instituto de Oftalmología Conde de Valenciana, Mexico City, Mexico. Electronic address:

We present a series of 4 cases of pressure-induced stromal keratopathy after laser in situ keratomileusis (LASIK). Four patients (5 eyes) with previous LASIK presented for poor visual acuity and ocular pain because of ocular hypertension. At examination, all cases revealed corneal haze and a space filled with fluid between the surgical flap and the residual stroma. Read More

Int J Numer Method Biomed Eng 2018 Dec 19;34(12):e3141. Epub 2018 Sep 19.

Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

The present work analyses the performance of four glaucoma drainage devices, by means of a novel patient-oriented numerical procedure. The procedure is based on the three-dimensional geometry reconstruction from the stacks of tomographic images of a human eye, at different angles, on meshing and on thermo-fluid dynamics modelling activities, carried out on the reconstructed computational domain. The current three-dimensional eye model considers anterior chamber (AC), trabecular meshwork, Schlemm's canal, and collector channels, making use of generalised porous medium approach for modelling ocular porous tissue and cavities. Read More

Am J Ophthalmol Case Rep 2018 Dec 29;12:15-17. Epub 2018 Jul 29.

Glaucoma Division, King Khaled Eye Specialist Hospital, Al-Arubah Branch Rd, Riyadh, 12329, Saudi Arabia.

Purpose: To report the effectiveness of Goniosynechialysis (GSL) treating elevated intraocular pressure (IOP) in an aphakic eye with peripheral anterior synechiae (PAS) formation after vitrectomy.

Observations: A 39-year-old gentleman with history of lamellar keratoplasty for corneal ectasia and blunt trauma to the right eye necessitating vitrectomy and lensectomy presented to our glaucoma unit with a secondary angle closure and an IOP of 50 mmHg. This was successfully treated with GSL and one year after surgery, the patient maintains a normal IOP without the use of medication. Read More

J Ophthalmic Vis Res 2018 Jul-Sep;13(3):219-223

Department of Ophthalmology, Eye Institute at Harborview, University of Washington Medical Center, Seattle, Washington, USA.

Purpose: This study evaluates the radiographic appearance of lacrimal gland tissue after placement of a glaucoma drainage implant (GDI) to characterize the impact of the device on the gland's imaging patterns.

Methods: We performed retrospective chart review of departmental records at two urban academic medical centers, which were systematically searched using procedure codes to identify adult glaucoma patients who underwent unilateral superotemporal GDI from January 1995 to December 2015. Radiology records were cross-checked to identify the subset of patients who underwent postoperative orbital CT or MRI. Read More

Ocul Immunol Inflamm 2018 Aug 6:1-6. Epub 2018 Aug 6.

a Advanced Eye Center , Post Graduate Institute of Medical Education and Research (PGIMER) , Chandigarh , India.

Purpose: To analyze the outcomes of surgical procedures on inciting eye of patients with Sympathetic ophthalmia (SO).

Methods: Retrospective study of patients with SO who underwent surgical procedures on inciting eyes between January 2000 and December 2015. Outcome measures included flare up of inflammation in either eye and change in visual acuity in the inciting eye. Read More

J Glaucoma 2018 Oct;27(10):929-930

University Hospitals of Leicester, Leicester Royal Infirmary Infirmary Square, Leicester, UK.

Neovascular glaucoma carries a poor visual prognosis and surgery is frequently required to control the intraocular pressure. For patients who have visual potential, conventional glaucoma surgery such as a glaucoma drainage device or trabeculectomy are frequently performed. Cyclophotocoagulation is often reserved for eyes with poor visual potential, blind eyes, or where for medical reasons it is not possible for patients to have conventional surgery. Read More

PLoS One 2018 26;13(7):e0201342. Epub 2018 Jul 26.

Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.

Purpose: To evaluate corneal endothelial cell loss after Baerveldt glaucoma implantation.

Methods: We prospectively evaluated changes in endothelial cell density (ECD) in the cornea of 59 patients (59 eyes) who underwent Baerveldt glaucoma implantation. Tubes were inserted into the anterior chamber in 45 eyes and pars plana in 14 eyes. Read More