Search Our Scientific Publications & Authors

J AAPOS 2019 Mar 15. Epub 2019 Mar 15.

Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina. Electronic address:

Purpose: To evaluate outcomes of strabismus surgery performed subequent to or concomitant with glaucoma drainage device (GDD) implantation for refractory childhood glaucoma.

Methods: The medical records of children who underwent strabismus surgery after or concomitantly with GDD implantation were reviewed retrospectively. Included were surgeries with motility and alignment data measured preoperatively and ≥3 months postoperatively. Read More

Eur J Pharm Sci 2019 Mar 12. Epub 2019 Mar 12.

Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS Deemed to be University, Mumbai, Maharashtra, India.

Glaucoma, a gradually progressive class of either chronic eye disease or disorder, occurs due to increasing intra-ocular pressure. To reduce glaucoma, it is essential to stop the progression of IOP in the eye which is achieved by medical treatment, laser treatment and surgery. Profuse conventional drugs and laser surgeries are the primary go-tos for decreasing IOP. Read More

Medicine (Baltimore) 2019 Mar;98(9):e14500

Xiamen University Affiliated Xiamen Eye Center, Xiamen, China.

Objective: The aim of the present study was to observe the feasibility and effect of cornea slice acquired from femtosecond laser surgery, small incision lenticule extraction (SMILE) as patch graft for the prevention of drainage tube exposure and to compare with the sclera.

Methods: The research is a prospective comparative randomized study. Patients who received Ahmed glaucoma valve implantation surgery from August 2015 to January 2017 at the Xiamen Eye Center were randomly divided into 2 groups. Read More

J Glaucoma 2019 Feb 21. Epub 2019 Feb 21.

Glaucoma Division, King Khaled Eye Hospital, Riyadh.

PRéCIS:: In this case-control study, female gender and older age were risk factors for tube exposure; risk was related to the number of prior ocular surgeries and scleral patch graft (compared to peroicardial graft) was found to protect against exposure.

Purpose: Identification of potential risk factors for glaucoma drainage device exposure may help to prevent this potentially blinding complication. The purpose of this study was to evaluate the possible risk factors for glaucoma drainage device exposure in a tertiary eye care center in the Middle-East. Read More

Med J Aust 2019 Mar 14;210(4):180-187. Epub 2019 Feb 14.

University of Sydney, Sydney, NSW.

Glaucoma is an irreversible progressive optic neuropathy, for which the major proven treatment is to lower the intraocular pressure (IOP). Five groups of IOP-lowering eye drops have varying mechanisms of action. Some drops, such as β-blockers and α-2 agonists, have potentially serious systemic side effects. Read More

Ocul Surf 2019 Feb 8. Epub 2019 Feb 8.

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, United States.

Purpose: Glaucoma is the leading cause of vision loss in eyes with Boston Keratoprosthesis (KPro). Glaucoma drainage devices (GDDs) have been shown to be effective in controlling glaucoma with KPro. Cicatricial conjunctival disease with forniceal shortening is a major challenge and limitation to the use of GDD. Read More

BMC Ophthalmol 2019 Feb 6;19(1):46. Epub 2019 Feb 6.

Affiliated Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Zhejiang, China.

Background: To investigate the occurrence of ciliochoroidal detachment (CCD), its risk factors and its impact on the success rate after Ahmed glaucoma valve (AGV) implantation.

Methods: This is a retrospective observational study carried out at Eye Hospital of Wenzhou Medical University, Zhejiang, China. Patients with uncontrolled glaucoma who underwent AGV implantation alone or combined with phacoemulsification (AGV-Phaco) in the hospital from April 1, 2013 to July 31, 2016 were included. Read More

J Glaucoma 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, United-Kingdom.

Purpose: To study the long term safety and efficacy of contact trans-scleral cyclodiode laser photocoagulation in eyes with refractory glaucoma after penetrating keratoplasty.

Patients And Methods: All consecutive patients who were treated with trans-scleral cyclodiode laser photocoagulation for refractory glaucoma following penetrating keratoplasty between March 1996 and February 2017 in a tertiary corneal transplantation service in the United-Kingdom. Only patients with a follow-up of five years were included. Read More

Int Ophthalmol 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology, University of Nigeria Teaching Hospital, PMB 01129, Ituku-Ozalla, Enugu, Nigeria.

Purpose: To investigate the current practice on glaucoma care with the aim of highlighting its poise to tackle this emerging sight-threatening disease in Nigeria.

Methods: This was a cross-sectional, descriptive, population-based survey involving 88 ophthalmologists. Information on their demographic characteristics, practice profile, challenges and prospects on glaucoma care was collected using a semi-structured, self-administered questionnaire in August 2016. Read More

J Glaucoma 2019 Feb;28(2):165-171

Duke University Department of Ophthalmology, Durham.

Purpose: Many surgeons remove the ripcord in the Baerveldt glaucoma drainage device to better control tube opening and intraocular pressure (IOP) lowering postoperatively. However, complications following Baerveldt implant surgery with or without ripcord removal are not well-characterized. We performed a prospective, randomized trial to test the hypothesis that scheduled ripcord removal decreases complications and final IOP. Read More

ACS Appl Mater Interfaces 2019 Mar 11;11(10):10244-10253. Epub 2019 Feb 11.

Department of Ophthalmology , The Second Affiliated Hospital of Harbin Medical University , Harbin , Heilongjiang 150081 , P. R. China.

Excessive fibrosis is the topmost factor for the defeat of surgical glaucoma drainage device (GDD) implantation. Adjuvant drug approaches are promising to help reduce the scar formation and excessive fibrosis. Opal shale (OS), as a natural state and noncrystalline silica substance with poriferous nature and strong adsorbability, is highly likely to undertake drug loading and delivery. Read More

J Glaucoma 2019 Jan 22. Epub 2019 Jan 22.

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio Network, Lausanne, Switzerland.

Introduction: Kabuki syndrome (KS) is a rare congenital and polymalformative condition, traditionally associated with mental retardation, unusual facial features and skeletal abnormalities. We hereby describe a case of bilateral congenital glaucoma associated with MLL2-mutation Kabuki Syndrome. To the best of our knowledge, this is the first association of KS with congenital glaucoma. Read More

J Glaucoma 2019 Jan 22. Epub 2019 Jan 22.

Glaucoma Research Centre, Monchoisi Clinic, Swiss Visio Network, Lausanne, Switzerland.

Introduction: While there are several examples of glaucoma drainage devices dislocations in the literature, the movement of XEN gel stents is scarcely documented and the impact of such displacements on the corneal endothelium remains unknown. In light of the recent global market withdrawal of the CyPass micro-stent over concerns regarding endothelial cell loss, we present a case of XEN gel stent dislocation into the anterior chamber, with localized corneal damage.

Case Report: We describe the case of a 64-year old female patient who underwent bilateral XEN gel stent implantation for normal tension glaucoma. Read More

J Glaucoma 2019 Jan 22. Epub 2019 Jan 22.

NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom.

Purpose: The aim of this study was to present a case of a Baerveldt glaucoma implant lumen being completely occluded with a 3-0 Supramid stent suture.

Patient And Methods: The patient underwent Baerveldt glaucoma implant surgery with placement of an intraluminal 3-0 Supramid stent suture that acts to restrict flow across the device and reduce the risk of postoperative hypotony. Following suturing of the implant to the sclera, the device was flow tested. Read More

Ocul Oncol Pathol 2019 Jan 2;5(1):20-27. Epub 2018 May 2.

Stein Eye and Doheny Eye Institutes, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

Aim: We report patient safety and intraocular pressure (IOP) control after placement of a glaucoma drainage device (GDD) in eyes with a history of treated malignant uveal melanoma.

Methods: A retrospective review of the records of patients with uveal melanoma was performed. Outcomes were local tumor recurrence, rate of metastases, and to-nometric success, based on survival curves, defined as IOP < 21 mm Hg. Read More

Indian J Ophthalmol 2019 Feb;67(2):233-238

Department of Glaucoma, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India.

Purpose: To report the intermediate-term safety and efficacy of Aurolab aqueous drainage implant (AADI) in patients with glaucoma.

Methods: Retrospective review of patients who underwent AADI between January 2013 and December 2016. Patients aged >16 years and with a minimum follow-up of 6 months were included. Read More

J Med Econ 2019 Apr 4;22(4):390-401. Epub 2019 Feb 4.

e Goeree Consulting Ltd, Hamilton , ON , Canada.

Objectives: To estimate the cost-utility of two trabecular micro-bypass stents (TBS) implantation vs standard of care (SOC) in patients with mild-to-moderate open-angle glaucoma (OAG) in the Canadian healthcare setting.

Methods: The deterioration in visual field (VF) defect over a 15-year time horizon was tracked using a Markov model with Hodapp-Parrish-Anderson stages of glaucoma (mild, moderate, advanced, severe/blind) and death as health states. Meta-analyses of randomized clinical trials were conducted to estimate the pooled reduction in intraocular pressure (IOP) and medication use due to TBS and SOC. Read More

BMC Ophthalmol 2019 Jan 10;19(1):14. Epub 2019 Jan 10.

Department of Ophthalmology, University Medical Center Schleswig-Holstein, Arnold-Heller Strasse 3, Haus 25, D-24105, Kiel, Germany.

Background: To evaluate long-term results of eyes with glaucoma drainage device (GDD).

Methods: We retrospectively reviewed medical records of all patients who underwent GDD placement at our institution between 2001 and 2014. A total of 110 eyes of 90 patients were studied. Read More

J Glaucoma 2019 Jan 8. Epub 2019 Jan 8.

Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles.

Purpose: To evaluate the outcomes of autologous limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness donor corneal allograft in management of tube erosion of glaucoma drainage device (GDD).

Methods: Consecutive patients who had undergone a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft were reviewed. Primary outcome was surgical success of coverage of the exposed tube without complications or additional surgeries. Read More

BMC Ophthalmol 2018 Dec 27;18(1):339. Epub 2018 Dec 27.

Department of Ophthalmology, Ruprecht-Karls-University Heidelberg, 69120, Heidelberg, Germany.

Purpose: To compare efficacy and safety results of an ab interno gel implant in patients with pseudoexfoliation glaucoma (PXG) and primary open angle glaucoma (POAG).

Methods: Retrospective analysis of the medical records of 110 consecutive eyes with open angle glaucoma who had received a XEN45 gel implant between March 2014 and June 2015. Intraocular pressure course, number of glaucoma medications, the need for additional intervention (including needling) and complications were evaluated until 12 months postoperatively. Read More

J Glaucoma 2018 Dec 24. Epub 2018 Dec 24.

Royal Blackburn and Burnley General Teaching Hospitals, East Lancashire Hospitals NHS Trust, Lancashire, UK.

A 78 old male with angle closure glaucoma and on treatment with oral anticoagulants, underwent phacoemulsification. An early acute suprachoroidal hemorrhage (SCH) occurred and the surgical wound was rapidly sutured without complete soft lens matter (SLM) removal, nor insertion of intraocular lens (IOL). The SCH was managed conservatively and it resolved in 5 weeks; the intraocular pressure was 35▒mm Hg despite maximal medical treatment. Read More

Clin Ophthalmol 2018 7;12:2545-2552. Epub 2018 Dec 7.

Department of Ophthalmology, University of Hong Kong, Hong Kong, People's Republic of China,

Purpose: This is a pilot study to compare the effectiveness and safety of diode laser transscleral cyclophotocoagulation (TSCP) with the Ahmed glaucoma valve (AGV) in the management of neovascular glaucoma (NVG).

Methods: Eyes with NVG and an IOP greater than 21 mmHg on maximal medications, without previous glaucoma surgery or cyclodestruction, were randomized for either TSCP or AGV implantation. These eyes were followed for at least 6 months and analyzed with respect to their visual outcome, IOP, number of glaucoma medications required, and related complications. Read More

Clin Ophthalmol 2018 28;12:2439-2449. Epub 2018 Nov 28.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan,

Purpose: To describe the 1-year surgical outcomes of both Baerveldt glaucoma implant (BGI) and the Ahmed glaucoma valve (AGV) implant with pars plana tube insertion in Japanese eyes with neovascular glaucoma (NVG).

Patients And Methods: This was a retrospective study of 21 eyes of 18 patients who had undergone BGI (10 eyes) or AGV (11 eyes) implantation. The 1-year surgical outcomes in the two groups were compared. Read More

Klin Monbl Augenheilkd 2018 Dec 19;235(12):1360-1365. Epub 2018 Dec 19.

Institut für ImplantatTechnologie und Biomaterialien e. V., Rostock-Warnemünde.

Purpose: Evaluation of the long-term efficiency of MIGS implants is still challenging, due to the lack of standardized clinical studies of stand-alone procedures. Moreover, the different mechanisms of the various glaucoma drainage devices are not adequately considered. The current study focusses on the development of a method for oculopression to evaluate the efficiency of glaucoma drainage devices. Read More

Curr Opin Ophthalmol 2019 Mar;30(2):125-131

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.

Purpose Of Review: This article reviews recent studies related to tube shunt surgery.

Recent Findings: Medical claims data and surveys of glaucoma surgeons demonstrate that tube shunts are being selected with increasing frequency as an alternative to trabeculectomy. A 5-year pooled analysis of the Ahmed Baerveldt comparison study and Ahmed versus Baerveldt study found a higher rate of surgical success with the Baerveldt glaucoma implant compared with the Ahmed glaucoma valve, but Baerveldt implantation carried a higher risk of hypotony. Read More

Cochrane Database Syst Rev 2018 12 16;12:CD012742. Epub 2018 Dec 16.

Ophthalmology, Nottingham University Hospital, Derby Road, Nottingham, UK, NG7 2UH.

Background: Glaucoma is a leading cause of irreversible blindness. Subconjunctival draining minimally-invasive glaucoma devices such as the Xen gelatin implant and InnFocus stent have been introduced as a treatment to prevent glaucoma progressing.These implants provide a channel to allow aqueous humour from the anterior chamber of the eye to drain into the subconjunctival space on the surface of the eye thus reducing intraocular pressure (IOP) and mimicking the mechanism of the most commonly undertaken glaucoma surgery, trabeculectomy. Read More

Korean J Ophthalmol 2018 Dec;32(6):523-524

Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, Korea.

Clin Exp Ophthalmol 2018 Dec 13. Epub 2018 Dec 13.

South Australian Institute of Ophthalmology, The University of Adelaide, Adelaide, Australia.

Importance: The demand for glaucoma care is projected to increase significantly with the ageing population.

Background: To characterize trends in Australian practice patterns for glaucoma management over the 15-y period between 2003 and 2017.

Design: Retrospective audit. Read More

Am J Ophthalmol 2019 Mar 28;199:150-158. Epub 2018 Nov 28.

Netherlands Institute for Innovative Ocular Surgery (NIIOS), Rotterdam, Netherlands; Melles Cornea Clinic Rotterdam, Rotterdam, Netherlands; Amnitrans EyeBank Rotterdam, Rotterdam, Netherlands; NIIOS-USA, San Diego, California, USA. Electronic address:

Purpose: To evaluate the feasibility and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with a glaucoma drainage device (GDD).

Design: Retrospective, interventional case series.

Methods: Clinical outcomes of 23 DMEK procedures for bullous keratopathy (52%), failed previous transplant (39%), or Fuchs endothelial corneal dystrophy (9%) in 20 eyes (19 patients) with a GDD were retrospectively analyzed at 2 tertiary referral centers. Read More

Vestn Oftalmol 2018 ;134(5. Vyp. 2):244-249

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

The XEN-45 drainage implant is a hypotensive device made of hydrophilic gelatin and stabilized by glutaraldehyde. The implant is designed for modern Microinvasive Glaucoma Surgery (MIGS). Being installed ab interno, the stent drains aqueous fluid from the anterior chamber into the subconjunctival space. Read More

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):498-500

Department of Ophthalmology, University of Virginia, School of Medicine, Charlottesville, Virginia, USA.

The modern glaucoma drainage implant era was initiated with implantation of a plate posterior to the limbus connected to the anterior chamber by a long silicone tube. Non-restrictive (Molteno and Baerveldt implants) and flow-restrictive (Ahmed Glaucoma Valve) implants were developed. With increased clinical experience, variables influencing success and failure of glaucoma drainage implant surgery were better understood. Read More

Eur J Ophthalmol 2018 Nov 26:1120672118815066. Epub 2018 Nov 26.

Hospital Sao Geraldo, HC-Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Objective:: To assess the feasibility of a novel surgical technique in painful blind eyes.

Design:: A prospective safety study conducted at the Federal University of Minas Gerais, Brazil.

Participants/samples:: A total of 15 end-stage glaucomatous eyes without light perception vision. Read More

Indian J Ophthalmol 2018 Dec;66(12):1820-1824

Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To evaluate the outcome of rhegmatogenous retinal detachment (RRD) surgery in eyes with preplaced glaucoma drainage device (GDD) with respect to intraocular pressure (IOP) control as well as success of retinal detachment (RD) surgery.

Methods: It is a retrospective case series. The case records of patients who underwent RD surgery after GDD implantation from 2000 to 2014 were screened. Read More

Surv Ophthalmol 2019 Mar - Apr;64(2):217-224. Epub 2018 Nov 3.

New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA; Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Insertion of glaucoma drainage devices has become a mainstay in the surgical management of multiple forms of glaucoma, and the indications for this procedure continue to expand. A unique clinical challenge in the postoperative care of these devices is the hypertensive phase, a period of postoperative intraocular pressure elevation in the first three months after surgery. We discuss the influence of a variety of factors on the development of the hypertensive phase after glaucoma drainage implantation, including type of device, device material, and device surface area. Read More

Indian J Ophthalmol 2018 11;66(11):1585-1586

Senior Glaucoma and Cataract Specialist Centre for Sight, Banjara Hills; Neoretina Eyecare Institute, Abids; Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, India.

Indian J Ophthalmol 2018 Nov;66(11):1580-1585

Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Purpose: To study the efficacy of the Aurolab aqueous drainage implant (AADI) compared to Ahmed glaucoma valve (AGV) in patients with refractory glaucoma.

Methods: This was a prospective, randomized controlled trial. Thirty-eight adult patients (>18 years) scheduled for a glaucoma drainage device (GDD) were randomized into two groups to receive either AGV or AADI. Read More

BMJ Case Rep 2018 Oct 21;2018. Epub 2018 Oct 21.

Department of Ophthalmology, Hospital de Santa Maria, Lisboa, Portugal.

A 51-year-old woman was referred with uncontrolled intraocular pressure (IOP) despite maximal medical IOP-lowering therapy. Her background included several failed glaucoma filtering surgeries, including aqueous drainage devices. Considering the need to perform surgery in a patient with both scarred conjunctiva and corneal endothelial deficiency, a surgical technique combining cornea-friendly XEN stent connected to a large-plate Baerveldt glaucoma implant was undertaken. Read More

Can J Ophthalmol 2018 Oct 7;53(5):510-517. Epub 2018 May 7.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.

Objective: To report and analyze the clinical outcomes of the first 250 cases of Descemet membrane endothelial keratoplasty (DMEK).

Methods: A retrospective case series was conducted on the first 250 DMEK cases. The cohort included eyes with previous trabeculectomy, pre-existing glaucoma drainage device, and previous vitrectomy. Read More

J Glaucoma 2019 Jan;28(1):56-60

Department of Ophthalmology, Hospital Santa Maria.

Purpose: The XEN gel stent is a minimally invasive surgical device aimed at creating a subconjunctival drainage of aqueous humor, thereby reducing intraocular pressure (IOP). Being a novel device, doubts remain with regard to the efficacy and safety of its implantation in the early stage of new users. This paper illustrates the XEN implantation learning curve, assessed through several surgeons of different expertise. Read More

Korean J Ophthalmol 2018 Oct;32(5):400-408

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: To evaluate the outcome of Ahmed glaucoma valve (AGV) implantation in eyes with refractory secondary glaucoma following pars plana vitrectomy (PPV) and the associated prognostic factors.

Methods: A total of 146 eyes in 146 patients who underwent AGV implantation after PPV (followed up for ≥1 year) were included. AGV implantation was considered successful when the intraocular pressure (IOP) was 6 to 21 mmHg regardless of using IOP-lowering medication. Read More

Korean J Ophthalmol 2018 Oct;32(5):391-399

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Purpose: To evaluate the long-term effects of early postoperative intraocular pressure (IOP) after Ahmed glaucoma valve (AGV) implantation on long-term surgical outcomes.

Methods: This retrospective, non-randomized study included 100 eyes of 100 patients who underwent AGV surgery. We divided the enrolled patients into four groups according to the presence of transient hypotony within the first postoperative week or the presence of a hypertensive phase during the first three postoperative months. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Jan 11;257(1):143-151. Epub 2018 Oct 11.

Department of Ophthalmology, Erasmus Medical Center, 's Gravendijkwal 230, 3000 CA, Rotterdam, The Netherlands.

Purpose: To assess the efficacy of glaucoma drainage devices (GDD) in uveitic glaucoma and non-uveitic glaucoma, and to perform a meta-analysis of previously published results to compare with our data.

Methods: Retrospective case-control study, in which all eyes that underwent GDD surgery were included from 2015 onwards. Cases were defined as patients with uveitic glaucoma. Read More

Acta Ophthalmol 2019 Mar 4;97(2):193-199. Epub 2018 Oct 4.

Department of Ophthalmology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Purpose: To determine the cost (loss of visual function associated with the procedure) and benefit (long-term preservation of the visual field) of glaucoma surgery.

Methods: We included 100 patients who underwent glaucoma surgery (Baerveldt glaucoma implant [BGI], n = 61; trabeculectomy [TE], n = 39). Preoperatively, the median (interquartile range [IQR]) standard automated perimetry mean deviation (MD) was -12 (-16 to -6) dB. Read More

BMC Ophthalmol 2018 Sep 14;18(Suppl 1):222. Epub 2018 Sep 14.

Western Eye Hospital, London, UK.

Background: The surgical management of patients with uncontrolled glaucoma and scleroderma is challenging, as the hostile ocular surface poses a challenge to surgery. A serious complication is tube erosion, with the risk of subsequent endophthalmitis. Here, we present a novel technique of harvesting autologous tissue to successfully manage recurrent tube extrusion. Read More

Medwave 2018 Sep 7;18(5):e7239. Epub 2018 Sep 7.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Oftalmología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Av. Diagonal Paraguay 476, Santiago, Chile.

Introduction: Aqueous shunt has emerged as an alternative technique to trabeculectomy, considered the standard for glaucoma surgery. Currently, it is mainly indicated after failure of trabeculectomy or in glaucoma with high risk of failure. The Ahmed valve and the Baerveldt implant are the most commonly used aqueous shunts. Read More

Retina 2018 Sep 17. Epub 2018 Sep 17.

Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio.

Purpose: To investigate the effect of serial anterior chamber (AC) paracenteses in eyes with sustained elevations of intraocular pressure (IOP) in the setting of repeated intravitreal injections (IVI) of anti-vascular endothelial growth factor medications.

Methods: This is a retrospective records review of patients undergoing IVI of anti-vascular endothelial growth factor medication (bevacizumab, ranubizumab, or aflibercept), who demonstrated a sustained elevation of preinjection IOP and also received AC paracentesis immediately after IVI on at least three consecutive visits. Changes in preinjection IOP and cup-to-disk (C:D) ratio were compared before and after the initiation of IVI and before and after the introduction of AC paracenteses with each subsequent IVI. Read More

Transl Vis Sci Technol 2018 Sep 13;7(5). Epub 2018 Sep 13.

Rotterdam Eye Hospital, Glaucoma Department, Schiedamse Vest 180 3011BH Rotterdam, The Netherlands.

Purpose: The purpose of this study was to quantify any diplopia and motility changes after the implantation of a Baerveldt glaucoma implant (BGI) or after trabeculectomy (TE).

Methods: We analyzed 51 patients with a BGI and 52 patients with a TE from a prospective cohort study. To quantify any diplopia, we asked patients about the presence of diplopia at 1 year after surgery. Read More

Cornea 2018 Nov;37 Suppl 1:S78-S85

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

Purpose: To restore vision in complex eyes with coexisting anterior and posterior segment problems, combined corneal transplantation (penetrating keratoplasty [PK] or Descemet-stripping automated endothelial keratoplasty [DSAEK]), pars plana vitrectomy (PPV), and/or flanged intrascleral intraocular lens (IOL) fixation, designated vitreocorneal surgery are performed. In this study, we evaluated the usefulness of vitreocorneal surgery for eyes with complex comorbidities.

Methods: Thirteen consecutive eyes in 13 patients with coexisting corneal pathology (ie, corneal scarring, bullous keratoplasty, corneal laceration) and posterior segment pathology (ie, aphakia without capsular support, retinal detachment, intravitreal foreign body) underwent vitreocorneal surgery. Read More

Ocul Immunol Inflamm 2018 Sep 13:1-8. Epub 2018 Sep 13.

a Manchester Royal Eye Hospital , Manchester University NHS Foundation Trust , Manchester , UK.

Purpose: This study investigated the efficacy and safety of Baerveldt glaucoma implants (BGI) in adults with uveitic glaucoma (UG) at the Manchester Uveitis Clinic.

Methods: This was a retrospective study of 42 patients with UG who underwent BGI implantation between 2006 and 2015. Primary outcome measures were intraocular pressure (IOP) reduction and number of medications at 5-year follow-up. Read More

BMC Ophthalmol 2018 Sep 10;18(1):243. Epub 2018 Sep 10.

Department of Ophthalmology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.

Background: To compare trabeculectomy and EX-PRESS device implantation procedures for treating glaucoma and evaluate changes in corneal endothelial cell density (CECD).

Methods: This study prospectively evaluated changes in the CECD in 60 eyes of 60 patients who underwent trabeculectomy and 50 eyes of 45 patients who underwent EX-PRESS device implantation. Baseline patient data recorded included age at surgery, sex, type of glaucoma medications, and lens status. Read More