250 results match your criteria Glaucoma Complications and Management of Glaucoma Filtering

Outcomes of combined phacoemulsification, anterior vitrectomy, and sclerectomy in nanophthalmic eyes with glaucoma.

Eye (Lond) 2022 Apr 5. Epub 2022 Apr 5.

Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.

Objectives: To compare the long-term efficacy and safety of combined phacoemulsification, anterior vitrectomy, and sclerectomy (triple procedure surgery, TS); combined phacoemulsification and anterior vitrectomy (double procedure surgery, DS); and filtering surgery (FS) in nanophthalmos with angle-closure glaucoma (NACG).

Methods: Retrospective cohort study. Forty patients (44 eyes) diagnosed with NACG who underwent TS, DS, and FS were included. Read More

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Combined nasal goniotomy - temporal trabeculotomy (NGTT) for circumferential angle surgery in primary congenital glaucoma.

Eur J Ophthalmol 2022 Mar 7:11206721221085395. Epub 2022 Mar 7.

Kasr Al-Aini Hospital - 63526Cairo University, Cairo, Egypt.

Purpose: To assess the safety and efficacy of combining nasal goniotomy with temporal trabeculotomy in the management of primary congenital glaucoma.

Design: Case series.

Methods: Fifteen eyes of eleven children (3-12 months old at presentation) were enrolled in this study after the establishment of PCG diagnosis based on the criteria placed by the World Glaucoma Association. Read More

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The surgical management of glaucoma: A review.

Ridia Lim

Clin Exp Ophthalmol 2022 03 17;50(2):213-231. Epub 2022 Jan 17.

Department of Ophthalmology, Sydney Eye Hospital, Sydney, Australia.

After a long period of little change, glaucoma surgery has experienced a dramatic rise in the number of possible procedures in the last two decades. Glaucoma filtering surgeries with mitomycin C and glaucoma drainage devices remain the standard of surgical care. Other newer surgeries, some of which are minimally or microinvasive glaucoma surgeries, target existing trabecular outflow, enhance suprachoroidal outflow, create subconjunctival blebs, or reduce aqueous production. Read More

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Long-term outcomes of viscocanalostomy and phaco-viscocanalostomy in patients with narrow angle glaucoma.

Graefes Arch Clin Exp Ophthalmol 2022 Jun 24;260(6):1995-2002. Epub 2021 Nov 24.

St Pauls Eye Unit, Liverpool University Hospital, Liverpool, UK.

Purpose: To assess the outcomes of viscocanalostomy and phaco-viscocanalostomy in patients with narrow angle glaucoma at a single tertiary eye centre.

Method: All patients undergoing viscocanalostomy for narrow angle glaucoma between June 2010 and June 2017 with a minimum follow-up of 12 months were included. Data was analysed from a prospectively maintained surgical outcome database. Read More

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Outcomes of bleb revision with ologen following filtering glaucoma surgery.

Eur J Ophthalmol 2021 Nov 6:11206721211053503. Epub 2021 Nov 6.

Glaucoma Associates of Texas, Dallas, Texas, USA.

Purpose: This study reports long-term outcomes of bleb revision with ologen™ Collagen Matrix (Aeon Astron Europe BV, the Netherlands) for the surgical management of various bleb-related issues including persistent bleb leaks with or without associated hypotony, bleb dysesthesia, overhanging blebs, or hypotony after filtering glaucoma surgery.

Materials And Methods: A retrospective chart review was performed for patients who underwent ologen bleb revision from 2012 to 2019 at Glaucoma Associates of Texas.

Results: The study included 23 eyes of 22 patients undergoing bleb revision with the ologen implant. Read More

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November 2021

[Application of Ultrasound Biomicroscopy in Longterm Follow-up Post Modified CO Laser-assisted Sclerectomy Surgery].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Oct;43(5):749-754

Department of Ophthalmology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

Objective To observe the role of ultrasound biomicroscopy(UBM)in two-year post-operative follow-up for primary open-angle glaucoma patients with modified CO laser-assisted sclerectomy surgery(CLASS).Methods This was a case series study.A combination of modified CLASS and preoperative laser iris management was administered to 28 eyes. Read More

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October 2021

Surgical Approach and Outcomes of Uveitic Glaucoma in a Tertiary Hospital.

J Curr Glaucoma Pract 2021 May-Aug;15(2):52-57

Department of Ophthalmology, Hospital Clinic de Barcelona, Innove Ocular-ICO Barcelona, Spain.

Aim And Objective: This study aimed to evaluate the performance of and indication for different surgical techniques in the management of uveitic glaucoma (UG).

Materials And Methods: A retrospective audit of records of all patients with UG who underwent ≥1 glaucoma surgery, between January 2007 and December 2016. The main outcomes were intraocular pressure (IOP) and the need for antihypertensive medication at each follow-up visit. Read More

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November 2021

Microcatheter-Assisted Trabeculotomy Combined With Deep Sclerectomy and Trabeculectomy in Young to Middle-Aged Adults With Advanced Primary Open-Angle Glaucoma: 1-Year Result.

Front Med (Lausanne) 2021 3;8:712332. Epub 2021 Sep 3.

Department of Ophthalmology, Shijiazhuang People's Hospital, Shijiazhuang, China.

We aimed to evaluate the safety and clinical efficacy of microcatheter-assisted trabeculotomy combined with deep sclerectomy and trabeculectomy (MATT-DS-Trab) in the surgical management of advanced primary open-angle glaucoma (POAG). According to the inclusion criteria, we retrospectively collected and analyzed 37 POAG cases in advanced stage who received MATT-DS-Trab. The intraocular pressure (IOP), best corrected visual acuity (BCVA), use of anti-glaucoma drugs, shape of the filtering bleb, size of the scleral lake, complications, and the surgical success rate were recorded. Read More

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September 2021

A Novel Procedure for the Management of Severe Hyphema after Glaucoma Filtering Surgery: Air-Blood Exchange under a Slit-Lamp Biomicroscopy.

Medicina (Kaunas) 2021 Aug 22;57(8). Epub 2021 Aug 22.

Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.

: This study introduces a novel office-based procedure involving air-blood exchange under a slit-lamp microscope for treatment of severe hyphema after filtering surgery. : This retrospective study enrolled 17 patients (17 eyes) with a diagnosis of primary open-angle glaucoma with severe hyphema (≥4-mm height) after filtering surgery. All patients were treated with air-blood exchange under a slit-lamp using room air (12 patients) or 12% perfluoropropane (C3F8; five patients). Read More

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Long-term outcomes of blebs repaired with scleral patch graft and conjunctival advancement in late-onset leak post-trabeculectomy.

Indian J Ophthalmol 2021 Sep;69(9):2496-2501

VST Centre for Glaucoma, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To report long-term outcomes in eyes that developed late-onset bleb leak post trabeculectomy, with or without hypotony and/or maculopathy, due to a scleral melt/fistula and who required a scleral patch graft and conjunctival advancement for repair.

Methods: Retrospective, non-comparative, interventional case series over a decade (2010-2019), presenting with late bleb leak post-filtration-surgery. All cases required a scleral patch graft and conjunctival advancement for management via a standard technique, performed by an experienced glaucoma surgeon. Read More

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September 2021

Real-world Surgical Outcomes of Primary Angle-closure Glaucoma.

Clin Ophthalmol 2021 29;15:2823-2833. Epub 2021 Jun 29.

Glaucoma Services, Department of Ophthalmology, Rajavithi Hospital and Rangsit Medical College, Bangkok, Thailand.

Purpose: To evaluate surgical outcomes of the four common procedures utilized for primary angle-closure glaucoma (PACG).

Methods: A retrospective study of survival rate in surgical management of PACG was conducted in a referral eye center. One hundred and ninety-nine eyes from 173 PACG patients were collected for chart review. Read More

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Management of strabismus related to infantile glaucoma: Case series.

Arch Soc Esp Oftalmol (Engl Ed) 2021 Jun 6;96(6):293-298. Epub 2021 Jan 6.

Servicio de Oftalmología, Hospital Clínico San Carlos, Madrid, Spain.

Objective: To evaluate the different modalities of treatment of the strabismus related to infantile glaucoma, its complications, and results.

Methods: The clinical history of 7 patients with infantile glaucoma which required strabismus surgical treatment were analyzed. Age at onset of glaucoma, type of glaucoma, glaucoma surgeries, type of strabismus, strabismus surgical treatment and postoperative results were studied. Read More

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Improving health-related quality of life in glaucoma during 11 years and its association with vision loss and treatment of the disease.

Acta Ophthalmol 2022 Feb 6;100(1):e221-e232. Epub 2021 May 6.

Department of Ophthalmology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Purpose: To evaluate the impact of glaucoma on health-related quality of life (HRQoL) and mental health in the ageing population of Finland.

Methods: Altogether 7380 and 5774 Finnish individuals aged 30 years and older with known eye disease status were studied in 2000 and 2011, respectively, in two population-based surveys, including an 11-year follow-up of 4683 participants. Data on HRQoL (EQ-5D-3L, 15D), depression (BDI), psychological distress (GHQ-12) and eye disease diagnoses were obtained from self-reported assessments. Read More

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February 2022

Efficacy of bleb-independent penetrating canaloplasty in primary angle-closure glaucoma: one-year results.

Acta Ophthalmol 2022 Feb 20;100(1):e213-e220. Epub 2021 Apr 20.

The Eye Hospital of Wenzhou Medical University, Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China.

Purpose: To report the efficacy and safety of bleb-independent penetrating canaloplasty in the management of primary angle-closure glaucoma (PACG).

Methods: This single-centre prospective interventional case series enrolled 57 eyes from 53 PACG patients with medically uncontrolled intraocular pressure (IOP) and peripheral anterior synechiae of over 270°. Penetrating canaloplasty, mainly consisted of tensioning suture-aided Schlemm's canal dilation and a trabeculectomy, was performed to create a direct communication between the anterior chamber and the Schlemm's canal. Read More

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February 2022

Specific postoperative complications of vitrectomy in hereditary transthyretin amyloidosis.

Eur J Ophthalmol 2021 Mar 29:11206721211006569. Epub 2021 Mar 29.

Department of Ophthalmology, Bicêtre Hospital, Assistance Publique - Hôpitaux de Paris, Paris-Saclay University, French Reference Center for Hereditary Transthyretin Amyloidosis (NNERF), French Reference Network for Rare Ophthalmic diseases (OPHTARA), Le Kremlin-Bicêtre, France.

Introduction: Vitrectomy may improve visual acuity of hereditary transthyretin amyloidosis (ATTRv) patients presenting with vitreous opacities but is associated with severe complications. The objective of this study is to report visual outcomes, early and late complications of a series of ATTRv patients who underwent vitrectomy in the French ATTRv reference center.

Methods: This retrospective, single-center study, included all ATTRv patients who underwent vitrectomy between 2002 and 2017. Read More

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Statin use and the reoperation rates in glaucoma filtration surgery - population-based cohort study.

Acta Ophthalmol 2022 Feb 23;100(1):e167-e173. Epub 2021 Mar 23.

Unit of Vitreoretinal Surgery, Department of Ophthalmology, Helsinki University Hospital, Research Programs, Individualized Drug Therapy, Helsinki University, Helsinki, Finland.

Purpose: To examine the association of systemic statin therapy and reoperation rate after glaucoma filtration surgery (GFS).

Methods: This is a population-based, historic cohort study of 2705 eyes undergoing GFS in Finland between July 2009 and December 2016. GFSs were identified from national administrative healthcare registers. Read More

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February 2022

Micropulse trans-scleral laser therapy outcomes for uncontrolled glaucoma: a prospective 18-month study.

Can J Ophthalmol 2021 12 10;56(6):371-378. Epub 2021 Feb 10.

Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Que.

Objective: To evaluate the efficacy and safety of micropulse trans-scleral laser therapy (mTLT) in glaucomatous patients.

Design: Prospective, interventional study in a university hospital setting.

Participants: Fifty-two eyes of 52 adult patients with uncontrolled glaucoma despite maximal tolerated medical treatment, and/or poor candidates for filtering surgery. Read More

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December 2021

Common and rare complications following filtering surgery for children with congenital glaucoma; a5 years study.

Eur J Ophthalmol 2021 Nov 9;31(6):3034-3041. Epub 2021 Jan 9.

The Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt.

Purpose: To determine the incidence of postoperative complications following combined trabeculotomy trabeculectomy with mitomycin C (CTTM) for congenital glaucoma (CG), in addition to documentation of some unusual complications and possible ways to manage these complications safely with minimal morbidity.

Methods: A retrospective observational study was performed on 190 eyes with CG had a CTTM procedure.Included eyes were operated upon between February 2015 and February 2020 in Sohag University Hospitals. Read More

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November 2021

A Tenon's capsule/bulbar conjunctiva interface biomimetic to model fibrosis and local drug delivery.

PLoS One 2020 3;15(11):e0241569. Epub 2020 Nov 3.

UCL Institute of Ophthalmology, UCL, London, United Kingdom.

Glaucoma filtration surgery is one of the most effective methods for lowering intraocular pressure in glaucoma. The surgery efficiently reduces intra-ocular pressure but the most common cause of failure is scarring at the incision site. This occurs in the conjunctiva/Tenon's capsule layer overlying the scleral coat of the eye. Read More

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December 2020

[Uveitic glaucoma in Behçet's disease: When everything gets complicated].

J Fr Ophtalmol 2020 Sep 1;43(7):635-641. Epub 2020 Jul 1.

Ophthalmology unit A, hôpital des spécialités, faculty of medicine and pharmacy, university Mohammed V, Rabat, Maroc.

Introduction: Behçet's disease is a systemic disease of unknown etiology. Its ocular manifestations are multiple and polymorphic, with uveitis at the top of the list. Classically, uveitis in Behçet's disease does not cause elevation of intraocular pressure. Read More

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September 2020

Personalising surgical treatments for glaucoma patients.

Prog Retin Eye Res 2021 03 18;81:100879. Epub 2020 Jun 18.

Department of Ophthalmology, University Hospital, Dijon, France; Centre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Université Bourgogne Franche-Comté, F-21000, Dijon, France.

Surgical treatments for glaucoma have relied for decades on traditional filtering surgery such as trabeculectomy and, in more challenging cases, tubes. Antifibrotics were introduced to improve surgical success in patients at increased risk of failure but have been shown to be linked to a greater incidence of complications, some being potentially vision-threatening. As our understanding of glaucoma and its early diagnosis have improved, a more individualised management has been suggested. Read More

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Measures to prevent the risks associated with exposure to cytostatic drugs in glaucoma filtering surgery.

Arch Soc Esp Oftalmol (Engl Ed) 2020 Jul 1;95(7):334-344. Epub 2020 Jun 1.

Institut Clínic d'Oftalmologia, ICOF, Hospital Clínic de Barcelona, España; Institut Oftalmològic Integral. Grup Admiravisión, Barcelona, España.

Introduction: The use of cytostatic drugs such as Mitomycin C and 5-Fluorouracil is well-known in glaucoma filtering surgery, as well as the management of its complications. However, there is a lack of information regarding the preventive measures to be taken by the professional that handles these types of substances.

Objective: Raise awareness among professionals of the risks associated with the use of cytostatic drugs without adequate prevention measures. Read More

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Bleb reconstruction using donor scleral patch graft for late bleb leak and hypotony.

Eur J Ophthalmol 2021 May 26;31(3):1039-1046. Epub 2020 May 26.

Department of Ophthalmology, 58010Royal Victoria Eye and Ear Hospital, Dublin, Ireland.

Purpose: Bleb dysfunction may occur as a late complication following glaucoma filtration surgery. Over-filtering, thinning and cystic blebs can lead to hypotony, leak and corneal dellen. We report our surgical management and outcomes of this specific entity using donor scleral patch grafts. Read More

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Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study.

Clin Ophthalmol 2020 12;14:795-803. Epub 2020 Mar 12.

Glaucoma Center Montchoisi Clinic, Lausanne, Switzerland.

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma.

Patients And Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma who underwent mDST. Outcome measures were: Surgical Success with 3 criteria - (i) criterion 1 = intraocular pressure (IOP) ≤21 mmHg or reduced by ≥20% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months; (ii) criterion 2 = IOP ≤18 mmHg or reduced by ≥30% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months and (iii) criterion 3 = IOP ≤15 mmHg or reduced by ≥40% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months; IOP Reduction; Use of Anti-glaucoma Medication; Complications; Visual Acuity and Postoperative Interventions. Read More

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Trabeculectomy in pregnancy: Case studies and literature review.

Indian J Ophthalmol 2020 03;68(3):420-426

VST Center for Glaucoma Care, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Glaucoma management during pregnancy is a challenge for the patient and doctor. During pregnancy, the intraocular pressure (IOP) decreases. However, some women with preexisting glaucoma have elevated IOP requiring enhanced medical treatment. Read More

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Prospective evaluation of penetrating deep sclerectomy in advanced open-angle glaucoma: Filtration surgery adapted to resource scarcity in developing countries.

J Fr Ophtalmol 2020 Mar 24;43(3):228-236. Epub 2020 Jan 24.

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio Network, Lausanne, Switzerland. Electronic address:

Purpose: Two of the hurdles that are facing ophthalmologists in developing countries are scarcity of resources and patient follow-up. Deep sclerectomy (DS) has proven less costly and more effective than topical therapies and has a more favorable safety profile than trabeculectomy. The main factors preventing its use in developing countries are the need to perform laser goniopuncture in 40-80% of cases to maintain filtration and the risk of postoperative iris incarceration. Read More

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Local peribulbar anesthesia before glaucoma filtering surgery in a patient with Brugada syndrome.

Eur J Ophthalmol 2021 Mar 6;31(2):NP39-NP42. Epub 2020 Jan 6.

Ophthalmology Unit, Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy.

We report anesthetic management in a patient with Brugada syndrome, an inherited syndrome characterized by normal QT interval, typical ST-segment-elevation in the right precordial leads, and increased risk of sudden cardiac death in the absence of myocardial ischemia or structural heart disease. A 69-year-old man scheduled for glaucoma filtering surgery underwent local peribulbar anesthesia using 5 mL of lidocaine 20 mg/mL solution that was slowly injected into two different sites approximately 10 min prior to the surgical procedure. The surgery proceeded uneventful and data of patient's blood pressure, heart rate, oxygen saturation were collected. Read More

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EyeWatch Rescue of Refractory Hypotony After Baerveldt Drainage Device Implantation: Description of a New Technique.

J Glaucoma 2020 Feb;29(2):e7-e10

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio.

The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address known complications of conventional filtering surgery. They are, however, associated with a higher rate of complications related to early hypotony and late corneal decompensation. Read More

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February 2020

Surgical outcomes following Muller Muscle-Conjunctival Resection in patients with glaucoma filtering surgery.

Orbit 2020 Oct 6;39(5):331-335. Epub 2019 Dec 6.

Division of Orbital and Oculoplastic Surgery, Stein and Doheny Eye Institutes, University of California, Los Angeles , Los Angeles, California, USA.

Purpose: Muller muscle-conjunctiva resection (MMCR) has been often considered to be relatively contraindicated in patients with previous glaucoma surgery. We investigate the glaucoma and ptosis outcomes in patients with glaucoma filtering blebs undergoing MMCR surgery.

Methods: Retrospective cross-sectional case-control study at a single institution over a 15-year period on eyes of patients > 18 years of age who underwent MMCR surgery were included. Read More

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October 2020

Management of the hyper-filtrating ischaemic bleb: crosslinking with riboflavin and UV radiation versus a conjunctival sliding flap and conjunctival autologous graft.

Arch Soc Esp Oftalmol (Engl Ed) 2020 Feb 23;95(2):64-70. Epub 2019 Nov 23.

Departamento de Oftalmología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), España.

Introduction: This article compares and evaluates the safety and clinical results of 3techniques for the management of hyper-filtrating ischaemic bleb in glaucoma, such as collagen crosslinking (CXL) with riboflavin versus conjunctival sliding and conjunctival autologous graft.

Methods: A total of 24 eyes were selected from 18 patients with ischemic blebs that underwent filtering glaucoma surgery between 2012 and 2017 and subjected them to crosslinking using riboflavin (n=4), conjunctival autologous graft (n=5), and conjunctival sliding (n=15). The results of the intraocular pressure (IOP) prior to the procedure and at 12 months were compared, as well as visual acuity and previous anti-glaucoma medication at 12 months. Read More

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February 2020