225 results match your criteria Glaucoma Complications and Management of Glaucoma Filtering


[Uveitic glaucoma in Behçet's disease: When everything gets complicated].

J Fr Ophtalmol 2020 Jul 1. Epub 2020 Jul 1.

Ophthalmology unit A, hôpital des spécialités, faculty of medicine and pharmacy, university Mohammed V, Rabat, Maroc.

Introduction: Behçet's disease is a systemic disease of unknown etiology. Its ocular manifestations are multiple and polymorphic, with uveitis at the top of the list. Classically, uveitis in Behçet's disease does not cause elevation of intraocular pressure. Read More

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http://dx.doi.org/10.1016/j.jfo.2019.12.005DOI Listing

Personalising surgical treatments for glaucoma patients.

Prog Retin Eye Res 2020 Jun 17:100879. Epub 2020 Jun 17.

Department of Ophthalmology, University Hospital, Dijon, France; Centre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Université Bourgogne Franche-Comté, F-21000, Dijon, France.

Surgical treatments for glaucoma have relied for decades on traditional filtering surgery such as trabeculectomy and, in more challenging cases, tubes. Antifibrotics were introduced to improve surgical success in patients at increased risk of failure but have been shown to be linked to a greater incidence of complications, some being potentially vision-threatening. As our understanding of glaucoma and its early diagnosis have improved, a more individualised management has been suggested. Read More

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http://dx.doi.org/10.1016/j.preteyeres.2020.100879DOI Listing

Measures to prevent the risks associated with exposure to cytostatic drugs in glaucoma filtering surgery.

Arch Soc Esp Oftalmol 2020 Jul 1;95(7):334-344. Epub 2020 Jun 1.

Institut Clínic d'Oftalmologia, ICOF, Hospital Clínic de Barcelona, España; Institut Oftalmològic Integral. Grup Admiravisión, Barcelona, España.

Introduction: The use of cytostatic drugs such as Mitomycin C and 5-Fluorouracil is well-known in glaucoma filtering surgery, as well as the management of its complications. However, there is a lack of information regarding the preventive measures to be taken by the professional that handles these types of substances.

Objective: Raise awareness among professionals of the risks associated with the use of cytostatic drugs without adequate prevention measures. Read More

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http://dx.doi.org/10.1016/j.oftal.2020.04.018DOI Listing

Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study.

Clin Ophthalmol 2020 12;14:795-803. Epub 2020 Mar 12.

Glaucoma Center Montchoisi Clinic, Lausanne, Switzerland.

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma.

Patients And Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma who underwent mDST. Outcome measures were: Surgical Success with 3 criteria - (i) criterion 1 = intraocular pressure (IOP) ≤21 mmHg or reduced by ≥20% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months; (ii) criterion 2 = IOP ≤18 mmHg or reduced by ≥30% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months and (iii) criterion 3 = IOP ≤15 mmHg or reduced by ≥40% of pre-operative IOP or IOP ≥6 mmHg on 2 consecutive time points after 3 months; IOP Reduction; Use of Anti-glaucoma Medication; Complications; Visual Acuity and Postoperative Interventions. Read More

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http://dx.doi.org/10.2147/OPTH.S244945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075434PMC

Trabeculectomy in pregnancy: Case studies and literature review.

Indian J Ophthalmol 2020 03;68(3):420-426

VST Center for Glaucoma Care, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Glaucoma management during pregnancy is a challenge for the patient and doctor. During pregnancy, the intraocular pressure (IOP) decreases. However, some women with preexisting glaucoma have elevated IOP requiring enhanced medical treatment. Read More

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http://dx.doi.org/10.4103/ijo.IJO_638_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043156PMC

EyeWatch Rescue of Refractory Hypotony After Baerveldt Drainage Device Implantation: Description of a New Technique.

J Glaucoma 2020 Feb;29(2):e7-e10

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio.

The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address known complications of conventional filtering surgery. They are, however, associated with a higher rate of complications related to early hypotony and late corneal decompensation. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001417DOI Listing
February 2020

Surgical outcomes following Muller Muscle-Conjunctival Resection in patients with glaucoma filtering surgery.

Orbit 2019 Dec 6:1-5. Epub 2019 Dec 6.

Division of Orbital and Oculoplastic Surgery, Stein and Doheny Eye Institutes, University of California, Los Angeles, Los Angeles, California, USA.

: Muller muscle-conjunctiva resection (MMCR) has been often considered to be relatively contraindicated in patients with previous glaucoma surgery. We investigate the glaucoma and ptosis outcomes in patients with glaucoma filtering blebs undergoing MMCR surgery.: Retrospective cross-sectional case-control study at a single institution over a 15-year period on eyes of patients > 18 years of age who underwent MMCR surgery were included. Read More

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http://dx.doi.org/10.1080/01676830.2019.1700283DOI Listing
December 2019

Management of the hyper-filtrating ischaemic bleb: crosslinking with riboflavin and UV radiation versus a conjunctival sliding flap and conjunctival autologous graft.

Arch Soc Esp Oftalmol 2020 Feb 23;95(2):64-70. Epub 2019 Nov 23.

Departamento de Oftalmología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), España.

Introduction: This article compares and evaluates the safety and clinical results of 3techniques for the management of hyper-filtrating ischaemic bleb in glaucoma, such as collagen crosslinking (CXL) with riboflavin versus conjunctival sliding and conjunctival autologous graft.

Methods: A total of 24 eyes were selected from 18 patients with ischemic blebs that underwent filtering glaucoma surgery between 2012 and 2017 and subjected them to crosslinking using riboflavin (n=4), conjunctival autologous graft (n=5), and conjunctival sliding (n=15). The results of the intraocular pressure (IOP) prior to the procedure and at 12 months were compared, as well as visual acuity and previous anti-glaucoma medication at 12 months. Read More

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http://dx.doi.org/10.1016/j.oftal.2019.10.003DOI Listing
February 2020

Comparative Effectiveness and Tolerance of Subliminal Subthreshold Transscleral Cyclophotocoagulation With a Duty Factor of 25% Versus 31.3% for Advanced Glaucoma.

J Glaucoma 2020 Feb;29(2):97-103

Department of Ophthalmology, Glaucoma Institute, Saint Joseph Hospital.

PRéCIS:: Subliminal subthreshold transscleral cyclophotocoagulation (SS-TSCPC) with duty cycles 25% and 31.3% seems to be an effective approach to reduce intraocular pressure (IOP) in glaucoma that is refractory to medical management.

Objective: The objective of this study was to compare the effectiveness and the tolerance of SS-TSCPC with a duty cycle of 25% versus 31. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001409DOI Listing
February 2020

The Management of Uveitic Glaucoma in Children

Turk J Ophthalmol 2019 Oct;49(5):283-293

Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust, United Kingdom

Children comprise a unique population of patients in regard to the diagnostic and therapeutic approach of uveitic glaucoma. The management of glaucoma secondary to uveitis in children is extremely challenging and presents various difficulties, which are associated both with the underlying uveitis and the young age of the patients. The treatment of uveitic glaucoma calls for a thorough and individualized approach, involving both pharmacotherapeutic and surgical modalities. Read More

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http://dx.doi.org/10.4274/tjo.galenos.2019.36589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823581PMC
October 2019

Ocular manifestations of Sturge-Weber syndrome.

Curr Opin Ophthalmol 2019 Sep;30(5):301-305

Nemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware, USA.

Purpose Of Review: Sturge-Weber syndrome (SWS) is a rare, congenital disease which frequently involves the eye. It is important that ophthalmologists recognize this syndrome and are aware of its range of ocular manifestations. The aim of this article is to present our understanding of the pathogenesis and clinical manifestations of this syndrome and provide updated information on the treatment of SWS glaucoma and choroidal hemangioma. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000597DOI Listing
September 2019
5 Reads

Management of Glaucoma in Pregnancy.

J Glaucoma 2019 10;28(10):937-944

Department of Ophthalmology, Indiana University School of Medicine, Eugene and Marilyn Glick Eye Institute, Indianapolis, IN.

Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patients' health decisions begin even before conception and continue throughout pregnancy and breastfeeding. The data on this topic is limited due to ethical and legal constraints and challenges of conducting large, prospective, and randomized clinical trials on this patient population. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001324DOI Listing
October 2019
7 Reads

Short-term incidence and management of glaucoma after successful surgery for stage 4 retinopathy of prematurity.

Indian J Ophthalmol 2019 06;67(6):917-921

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: The purpose of this study is to describe the short-term incidence, clinical features, and management of glaucoma in children after successful surgery for stage 4 retinopathy of prematurity (ROP).

Methods: The retrospective study included all eyes undergoing successful surgery for stage 4 ROP with good outcomes at a tertiary eye care center between June 2014 and June 2016. Cases developing postoperative glaucoma underwent examination under anesthesia for measurement of intraocular pressures (IOP), corneal diameters, Retcam-assisted fundus imaging, and gonioscopy. Read More

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http://dx.doi.org/10.4103/ijo.IJO_33_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552587PMC
June 2019
7 Reads
0.927 Impact Factor

Initial Clinical Results of the eyeWatch: a New Adjustable Glaucoma Drainage Device Used in Refractory Glaucoma Surgery.

J Glaucoma 2019 05;28(5):452-458

Glaucoma Center, Montchoisi Clinic, Lausanne, Vaud.

PRéCIS:: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted.

Purpose: The main purpose of this study was to evaluate the safety and efficacy of the new adjustable glaucoma drainage device eyeWatch used in conjunction with a Baerveldt glaucoma implant in refractory glaucoma. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001209DOI Listing
May 2019
16 Reads

Prospective study on a novel treatment for leaking cystic bleb: Efficacy and safety of collagen crosslinking.

Clin Exp Ophthalmol 2019 08 17;47(6):749-756. Epub 2019 May 17.

Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.

Importance: Management of cystic bleb leak is difficult. It would be essential to look for a method to strengthen the original pathological conjunctiva and reverse bleb leak.

Background: To evaluate the long-term efficacy and safety of collagen crosslinking in patients with leaking cystic bleb. Read More

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http://dx.doi.org/10.1111/ceo.13520DOI Listing
August 2019
7 Reads

Incidence, clinical profile, and short-term outcomes of post-traumatic glaucoma in pediatric eyes.

Indian J Ophthalmol 2019 Apr;67(4):509-514

Glaucoma Unit, Shri Ganesh Vinayak Eye Hospital, Raipur, Chhattisgarh, India.

Purpose: To report the incidence, modes of injury, treatment, and short-term outcomes in eyes with post-traumatic elevated intraocular pressure (IOP).

Methods: This was a 5-year hospital-based retrospective study of children ≤16 years who presented with open (OGI) or closed globe injury (CGI) and developed elevated IOP >21 mmHg. Those with a minimum follow up of 3 months were included. Read More

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http://dx.doi.org/10.4103/ijo.IJO_655_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446624PMC
April 2019
23 Reads

[XEN Gel Stent for management of chronic open angle glaucoma: A review of the literature (French translation of the article)].

J Fr Ophtalmol 2019 Apr 14;42(4):391-403. Epub 2019 Mar 14.

Service d'ophtalmologie, centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France; Service d'ophtalmologie, université de Versailles Saint-Quentin-en-Yvelines, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-De-Gaulle, 92100 Boulogne Billancourt, France; Inserm, U968, université UPMC Paris VI, UMR S 968, institut de la vision , CNRS, UMR 7210, 75012 Paris, France. Electronic address:

Purpose: The purpose of this study was to analyze the change in intraocular pressure (IOP) and glaucoma medications using the XEN Gel Stent as a solo procedure or in association with phacoemulsification in patients with chronic open angle glaucoma (OAG).

Methods: We included cohort studies with at least one year of follow-up in patients with primary open angle glaucoma (POAG), pseudo-exfoliative glaucoma (PXG) or pigmentary glaucoma (PG) who received a XEN® gel stent. The main outcome measure was IOP reduction at 12 months follow-up. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.10.005DOI Listing
April 2019
9 Reads

Benefits of SubCyclo Laser Therapy Guided by High-frequency Ultrasound Biomicroscopy in Patients With Refractory Glaucoma.

J Glaucoma 2019 06;28(6):535-539

Department of glaucoma institute, Saint Joseph Hospital Paris, Paris, France.

Purpose: The purpose of this study was to evaluate the efficacy and safety of subliminal cyclophotocoagulation using a 25% duty cycle diode laser (Supra 810, SubCyclo, Quantel Medical).

Methods: This was a pilot study of patients who underwent a SubCyclo photocoagulation procedure with a 25% duty cycle, between April 2016 and April 2017 at the Glaucoma Institute of Saint Joseph Hospital of Paris. All patients presented with an evolving moderate to severe glaucoma that were resistant to previous surgical treatments or with a contraindication for filtration surgery. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001230DOI Listing

XEN Implant for Glaucoma Treatment: A Review of the Literature.

Semin Ophthalmol 2019 21;34(2):93-97. Epub 2019 Feb 21.

b 2nd Department of Ophthalmology , National and Kapodistrian University of Athens , Athens , Greece.

Purpose: The purpose of this review is to summarize current knowledge on XEN implant for the treatment of glaucoma.

Methods: A comprehensive literature review has been performed regarding XEN implant and its use on glaucoma management. Forty-two articles were checked and 37 were found to be relevant. Read More

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https://www.tandfonline.com/doi/full/10.1080/08820538.2019.1
Publisher Site
http://dx.doi.org/10.1080/08820538.2019.1581820DOI Listing
April 2019
18 Reads

XEN Gel Stent for management of chronic open angle glaucoma: A review of the literature.

J Fr Ophtalmol 2019 Feb 22;42(2):e37-e46. Epub 2019 Jan 22.

Service d'ophtalmologie, centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU ForeSight, , 28, rue de Charenton, 75012 Paris, France; Service d'ophtalmologie, hôpital Ambroise-Paré, université de Versailles Saint-Quentin-en-Yvelines, AP-HP, 9, avenue Charles-De-Gaulle, 92100 Boulogne-Billancourt, France; Inserm, U968, université UPMC Paris VI, UMR S 968, institut de la vision, CNRS, UMR 7210, 75012 Paris, France. Electronic address:

Purpose: The purpose of this study was to analyze the change in intraocular pressure (IOP) and glaucoma medications using the XEN Gel Stent as a solo procedure or in association with phacoemulsification in patients with chronic open angle glaucoma (OAG).

Methods: We included cohort studies with at least one year of follow-up in patients with primary open angle glaucoma (POAG), pseudo-exfoliative glaucoma (PXG) or pigmentary glaucoma (PG) who received a XEN gel stent. The main outcome measure was IOP reduction at 12 months follow-up. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.12.002DOI Listing
February 2019
14 Reads

Glaucoma secondary to intraocular tumors: mechanisms and management.

Curr Opin Ophthalmol 2019 Mar;30(2):71-81

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.

Purpose Of Review: Glaucoma secondary to intraocular tumors is important to consider in eyes with a known tumor and those with unilateral or refractory glaucoma. The purpose of this review is to discuss the mechanisms and management of intraocular tumors with related secondary glaucoma.

Recent Findings: Several intraocular tumors can lead to glaucoma, including iris melanoma, iris metastasis, iris lymphoma, trabecular meshwork melanoma, choroidal melanoma, choroidal metastasis, retinoblastoma, and medulloepithelioma. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000550DOI Listing
March 2019
36 Reads

Hypertrophic dysaesthetic blebs following ab-interno gel stent (Xen) glaucoma surgery: management and 'redirect' revision surgery.

Clin Exp Ophthalmol 2018 12 28;46(9):1093-1095. Epub 2018 Jun 28.

Department of Ophthalmology, Royal Surrey County Hospital, Guildford, UK.

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http://dx.doi.org/10.1111/ceo.13335DOI Listing
December 2018
14 Reads

Glaucoma Secondary to Uveitis in Children in a Tertiary Care Referral Center.

Ocul Immunol Inflamm 2019 2;27(3):456-464. Epub 2018 Feb 2.

a Department of Ophthalmology , Postgraduate Institute of Medical Education and Research , Chandigarh , India.

: To study outcome of secondary glaucoma in pediatric uveitis patients. Retrospective analysis of records of uveitis patients ≤16 years. : Of 182 pediatric uveitis patients, secondary glaucoma was seen in 48 patients (75 eyes, 26. Read More

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http://dx.doi.org/10.1080/09273948.2017.1411517DOI Listing
December 2019
10 Reads

The XEN45 Gel Stent as a minimally invasive procedure in glaucoma surgery: success rates, risk profile, and rates of re-surgery after 261 surgeries.

Graefes Arch Clin Exp Ophthalmol 2018 Apr 22;256(4):765-771. Epub 2018 Jan 22.

Department of Ophthalmology, St. Martinus-Krankenhaus Düsseldorf, Gladbacher Str. 26, D-40219, Düsseldorf, Germany.

Purpose: The XEN45 Gel Stent is a flexible hydrophilic tube placed under the conjunctiva via the anterior chamber. This study investigates the IOP (intraocular pressure)-lowering potential, the risk profile, and the success rate of the XEN45 Gel Stent.

Methods: Two hundred and sixty-one eyes underwent surgery. Read More

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http://dx.doi.org/10.1007/s00417-018-3899-7DOI Listing
April 2018
11 Reads

Glaucoma-associated corneal endothelial cell damage: A review.

Surv Ophthalmol 2018 Jul - Aug;63(4):500-506. Epub 2017 Nov 14.

Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA. Electronic address:

The corneal endothelium is critical in maintaining a healthy and clear cornea. Corneal endothelial cells have a significant reserve function, but preservation of these cells is paramount as they have limited regenerative capacity. Glaucoma is a prevalent disease, and damage to the corneal endothelium may be caused by the disease process itself as well as by its treatment. Read More

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http://dx.doi.org/10.1016/j.survophthal.2017.11.002DOI Listing
September 2018
21 Reads

Anticoagulation in Glaucoma Surgery.

Semin Ophthalmol 2018 16;33(1):108-111. Epub 2017 Nov 16.

a Glaucoma Service, Department of Ophthalmology , Massachusetts Eye and Ear, Harvard Medical School , Boston , MA , USA.

Anticoagulation medications are used commonly, particularly in an elderly population. There are many systemic diseases and scenarios that require modulation of coagulation to prevent serious adverse outcomes. While there is some consensus about their use in cataract surgery, there is less certainty about their management with glaucoma surgery. Read More

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http://dx.doi.org/10.1080/08820538.2017.1353828DOI Listing
February 2018
24 Reads

Management of Delayed Suprachoroidal Hemorrhage after Glaucoma Surgery.

Semin Ophthalmol 2018 16;33(1):59-63. Epub 2017 Nov 16.

a Retina Service, Department of Ophthalmology , Massachusetts Eye and Ear, Harvard Medical School , Boston , MA , USA.

Purpose: To review the most current treatment recommendations and outcomes for delayed suprachoroidal hemorrhages.

Methods: Article review of management and outcomes of suprachoroidal hemorrhages, with emphasis on delayed suprachoroidal hemorrhages in the setting of glaucoma surgery.

Conclusion: Time of drainage of suprachoroidal hemorrhages remains controversial. Read More

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http://dx.doi.org/10.1080/08820538.2017.1353814DOI Listing
February 2018
21 Reads

[Outpatient management without day 1 clinical follow-up of patients undergoing uncomplicated filtering surgery].

J Fr Ophtalmol 2017 Dec 1;40(10):853-859. Epub 2017 Nov 1.

Service d'ophtalmologie, université de Lorraine, CHRU de Nancy-Brabois, 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France. Electronic address:

Introduction: Although the general increase in ambulatory surgery allows for a 20% reduction in costs of hospitalization, the necessity of a day 1 postoperative visit remains the main problem for elderly patients or those who reside at considerable distance. For these reasons, in 2014, we decided to only see patients with uncomplicated filtering surgery at D5 and D21 and to replace the D1 visit with a telephone call. The primary goal of our study was to analyze a population of patients undergoing uncomplicated filtering surgery who were not seen at D1 and to describe the frequency of postoperative complications, intraocular pressure results and therapeutic management at D5 and D21. Read More

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http://dx.doi.org/10.1016/j.jfo.2017.04.013DOI Listing
December 2017
8 Reads

Revision of a Leaking Bleb With XEN Gel Stent Replacement.

J Glaucoma 2018 01;27(1):e11-e13

Glaucoma Research Center, Montchoisi Clinic, Swiss Vision Network, Lausanne, Switzerland.

Minimally invasive glaucoma surgery includes different devices which provide a less invasive and safer means of reducing intraocular pressure. The XEN Gel Stent (Allergan Inc., CA) is an ab interno procedure which creates a subconjunctival drainage pathway. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000811DOI Listing
January 2018
5 Reads

Co-management of cataract and glaucoma in the era of minimally invasive glaucoma surgery.

Curr Opin Ophthalmol 2018 Jan;29(1):88-95

aDepartment of Ophthalmology and Visual Sciences, University Hospitals, Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OhiobMill Valley Eye Center, Mill Valley, CAcEye Institute, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Purpose Of Review: This review discusses the options available to be used in conjunction with phacoemulsification cataract surgery to control intraocular pressure. We present a strategy for planning which surgery should be performed based on goals of care.

Recent Findings: New clinical evidence for using the CyPass, Kahook and Xen45 devices has been published recently and is summarized. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000444DOI Listing
January 2018
15 Reads

Ab Interno Gel Implant for the Treatment of Glaucoma Patients With or Without Prior Glaucoma Surgery: 1-Year Results.

J Glaucoma 2017 Dec;26(12):1130-1136

International Vision Correction Research Center (IVCRC), University of Heidelberg, Germany.

Purpose: The purpose of this study is to evaluate IOP lowering effects and complication management of an ab interno gel implant for the treatment of patients refractory to antiglaucoma medication or glaucoma surgery.

Methods: Retrospective analysis of the medical records of 242 consecutive eyes of 146 patients with uncontrolled intraocular pressure (IOP) despite maximum tolerated medical therapy or prior surgical intervention that underwent XEN45 implantation (as sole procedure or in combination with cataract surgery) between March 2014 and June 2015. Data included IOP, number of glaucoma medications, the need for additional surgery, needling, and complications. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000803DOI Listing
December 2017
67 Reads

Practice Preferences for Glaucoma Surgery: A Survey of the American Glaucoma Society.

J Glaucoma 2017 Aug;26(8):687-693

*Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, Icahn School of Medicine, New York, NY †Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL ‡Department of Ophthalmology, University of Washington, Seattle, WA.

Purpose: The purpose of this study is to assess surgical practice patterns among the American Glaucoma Society (AGS) membership.

Methods: An anonymous online survey evaluating the use of glaucoma surgeries in various clinical settings was redistributed to AGS members. Survey responses were compared with prior results from 1996, 2002, and 2008 to determine shifts in surgical practice patterns. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726398PMC
August 2017
62 Reads

Descemet's Membrane Dehiscence Resulting From Misdirected Viscoelastic During Anterior Chamber Reformation.

Eye Contact Lens 2018 Sep;44 Suppl 1:S355-S357

Department of Ophthalmology (E.C.), Eye and Ear Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; Department of Ophthalmology (G.D.), Northwell Health Physician Partners, Great Neck, NY; Department of Ophthalmology (W.S.), State University of New York Downstate Medical Center, Kings County Hospital Center, Brooklyn, NY; and Department of Ophthalmology (D.L.), State University of New York Downstate Medical Center/Kings County Hospital Center, Brooklyn, NY and NYU Langone Medical Center, New York, NY.

We report a case of Descemet's membrane detachment after inadvertent intrastromal injection of hyaluronic acid. Surgical removal was attempted with minimal but slow improvement. Near-complete resolution occurred with subsequent conservative management within 6 weeks. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000378DOI Listing
September 2018
70 Reads

Subconjunctival implantation of ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery.

Eye (Lond) 2017 Oct 2;31(10):1475-1479. Epub 2017 Jun 2.

Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, Shimane, Japan.

PurposeTo report the results of subconjunctival ologen Collagen Matrix implantation to manage ocular hypotony after filtration glaucoma surgery.Patients and methodsThis retrospective observational case series included 12 consecutive implantations of ologen in nine eyes of nine Japanese subjects (five men, four women; mean age±SD, 72.1±12. Read More

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http://dx.doi.org/10.1038/eye.2017.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639202PMC
October 2017
5 Reads

Assessment of conditions affecting surgical success of Ahmed glaucoma valve implants in glaucoma secondary to different uveitis etiologies in adults.

Eye (Lond) 2017 Oct 19;31(10):1435-1442. Epub 2017 May 19.

Department of Ophthalmology, Ankara Training and Research Hospital Ankara, Turkey.

PurposeThere is little known about the long-term efficacy and safety of Ahmed glaucoma valve (AGV) implant and about the conditions affecting surgical success in uveitic glaucoma (UG).Patients and methodsThe charts of adult patients with UG who underwent AGV implantation from 2006 to 2015 were reviewed retrospectively.ResultsData of 46 eyes of 39 patients were evaluated. Read More

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http://dx.doi.org/10.1038/eye.2017.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639197PMC
October 2017
67 Reads

Surgical Management of Pediatric Glaucoma.

Dev Ophthalmol 2017 25;59:165-178. Epub 2017 Apr 25.

Pediatric glaucoma surgery is challenging because of the differences in anatomy from the adult, differences in the behavior of the tissues of a child's glaucomatous eye, the variety in causes of the disease, and difficulties with postoperative management. Goniotomy and trabeculotomy are the preferred initial treatments for primary congenital glaucoma. Trabeculectomy with adjunctive mitomycin C is more likely to succeed in older, phakic patients, but carries the long-term risk of bleb-associated endophthalmitis. Read More

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http://dx.doi.org/10.1159/000458495DOI Listing
September 2017
59 Reads

Management of Concomitant Cataract and Glaucoma.

Dev Ophthalmol 2017 25;59:155-164. Epub 2017 Apr 25.

The coexistence of cataract and glaucoma represents a challenge for the ophthalmologist and the issue is still open to debate. The surgical management is based on both the visual field defect and the loss of visual acuity. The surgical options currently available are: (1) cataract extraction alone, (2) sequential glaucoma surgery and cataract extraction, and (3) combined surgery by 1 site or by 2 separate sites. Read More

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http://dx.doi.org/10.1159/000458494DOI Listing
September 2017
30 Reads

Viscocanalostomy and Canaloplasty: ab Externo Schlemm's Canal Surgery.

Dev Ophthalmol 2017 25;59:113-126. Epub 2017 Apr 25.

University Hospital Basel, Department of Ophthalmology, Basel, Switzerland.

Ab externo Schlemm's canal (SC) surgery (e.g., viscocanalostomy and canaloplasty) is a valuable alternative to glaucoma filtration surgery. Read More

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http://dx.doi.org/10.1159/000458491DOI Listing
September 2017
9 Reads

Ocular Surface and External Filtration Surgery: Mutual Relationships.

Dev Ophthalmol 2017 25;59:67-79. Epub 2017 Apr 25.

Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, Sorbonne Universités, UPMC University Paris 06, INSERM, CNRS, Institut de la Vision, Paris, and University of Versailles, Saint-Quentin-en-Yvelines, France.

There is a large body of evidence from clinical and experimental studies indicating that the long-term use of topical drugs may induce ocular surface changes, causing ocular discomfort, dry eye, conjunctival inflammation, subconjunctival fibrosis, corneal surface impairment, and, as a consequence of chronic ocular surface changes, the potential risk of failure for further glaucoma surgery. Subclinical inflammation has also been widely described in patients receiving antiglaucoma treatments for long periods of time, with inflammatory cell infiltration and fibroblast activation in the conjunctiva and subconjunctival space. Preservatives, especially benzalkonium chloride, which has consistently demonstrated its toxic effects in laboratory, experimental, and clinical studies, could induce or enhance such inflammatory changes, and has been recently confirmed as a direct risk factor of surgical failure. Read More

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http://dx.doi.org/10.1159/000458487DOI Listing
September 2017
31 Reads

Postoperative Management of Penetrating and Nonpenetrating External Filtering Procedures.

Dev Ophthalmol 2017 25;59:53-66. Epub 2017 Apr 25.

Correct postoperative management is fundamental to prevent and treat complications and to optimize the success of filtering surgery. Timely control visits and appropriate actions and prescriptions ensure the best outcomes, allow recovery from a number of untoward events, and can reestablish filtration when failure seems imminent. In contrast, a slack follow-up and wrong interventions or prescriptions can lead to the failure of any surgery, no matter how accurately it was carried out, sometimes jeopardizing vision and even the anatomy of the globe. Read More

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http://dx.doi.org/10.1159/000458486DOI Listing
September 2017
9 Reads

Initial Trabeculectomy With Mitomycin-C for Secondary Glaucoma-associated With Uveitis in Behçet Disease Patients.

J Glaucoma 2017 Jul;26(7):603-607

*Department of Ophthalmology, University of Tokyo School of Medicine †Department of Ophthalmology, Japan Community Health Care Organization Tokyo Shinjuku Center, Tokyo, Japan.

Purpose: To examine clinical outcomes following an initial trabeculectomy with mitomycin-C for secondary glaucoma associated with uveitis in Behçet disease (BD) patients.

Design: Retrospective interventional case series.

Patients And Methods: Twenty-two eyes in 18 patients with uveitic glaucoma (UG) associated with Behçet disease who underwent an initial trabeculectomy with mitomycin-C between January 1996 and August 2014 were retrospectively reviewed. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000665DOI Listing
July 2017
45 Reads

High intensity focused ultrasound as first line treatment in patients with chronic angle closure glaucoma at risk for malignant glaucoma.

J Fr Ophtalmol 2017 Apr 23;40(4):264-269. Epub 2017 Mar 23.

Ophthalmology department, Institut du glaucome, university Paris-Descartes, centre hospitalier Paris-Saint-Joseph, 185, rue Raymond-Losserand, 75674 Paris cedex 14, France.

Purpose: Evaluation of high intensity focused ultrasound (HIFU) transscleral cyclocoagulation as an alternative to trabeculectomy in the treatment of refractory chronic angle closure glaucoma (CACG).

Methods: This prospective one armed single center pilot study was conducted on patients with medically uncontrolled CACG who underwent high intensity focused ultrasound (HIFU) cyclocoagulation as first line surgical treatment, using the Eye-OP1 HIFU device (Eyetechcare-Rillieux-la-Pape, France) driven by ultrasound biomicroscopic (UBM) ciliary body localization. All patients had documented progression of their glaucoma despite conventional medical and laser therapy. Read More

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http://dx.doi.org/10.1016/j.jfo.2016.10.013DOI Listing
April 2017
52 Reads

Unusual Surprises in Glaucoma Filtering Surgeries: Lessons Learned and Review of Literature.

Semin Ophthalmol 2018 8;33(2):242-252. Epub 2016 Dec 8.

b Glaucoma Services, LV Prasad Eye Institute , Hyderabad , India.

Purpose: To describe an unusual series of complications after glaucoma filtering surgeries with their clinical findings and outcome after tailored non-conventional modes of therapy.

Patients And Methods: Eighteen patients who underwent re-interventions (medical or surgical) after glaucoma filtering surgeries during the period at two tertiary centers, excluding those that required conventional modes of treatment (medical control or re-trabeculectomy, simple wound closure for traumatic wound dehiscence, bleb revision or needling, laser iridotomy), were included. Relevant clinical details with intraoperative videos, intraoperative or postoperative problems, and images with course after re-intervention were retrieved from the hospital database. Read More

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http://dx.doi.org/10.1080/08820538.2016.1208766DOI Listing
April 2018
29 Reads

Ab Interno Trabeculectomy With the Trabectome as a Valuable Therapeutic Option for Failed Filtering Blebs.

J Glaucoma 2016 09;25(9):758-62

Eye Center, University of Freiburg, Freiburg, Germany.

Purpose: Uncontrolled intraocular pressure (IOP) after glaucoma filtration surgery is a challenging problem in the management of glaucoma patients. The Trabectome is a device for selective electroablation of the trabecular meshwork through a clear cornea incision without affecting the conjunctiva. Minimally invasive glaucoma surgery using the Trabectome is safe and effective as primary glaucoma surgery. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000492DOI Listing
September 2016
44 Reads

Bleb Revision With Temporalis Fascia Autograft.

J Glaucoma 2017 Jan;26(1):e11-e14

*Quinze-Vingt National Ophthalmology Hospital, Department II of Pr Nordmann †Quinze-Vingt National Ophthalmology Hospital, Department IV of Pr Sael, Hospital 28, rue de Charenton, 75571 PARIS Cedex 12.

Purpose: We report the first description of temporalis fascia autograft to repair a late leakage bleb with scleral defect that occurred long time after trabeculectomy with mitomycin C.

Patient: A 65-year-old woman was referred to our hospital with chronic late bleb leakage on her right eye. She had previously undergone a trabeculectomy with mitomycin C 3 years ago for a pigmentary glaucoma. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000486DOI Listing
January 2017
12 Reads

A New Method for Revision of Encapsulated Blebs after Trabeculectomy: Combination of Standard Bleb Needling with Transconjunctival Scleral Flap Sutures Prevents Early Postoperative Hypotony.

PLoS One 2016 17;11(6):e0157320. Epub 2016 Jun 17.

Department of Ophthalmology, University Medical Center, Johannes Gutenberg- University Mainz, Mainz, Germany.

Purpose: A simple needling procedure is the standard method for restoring the function of an encapsulated bleb after trabeculectomy. However, postoperative hypotony represents a possible hazard. This study describes a new surgical approach for treating encapsulated blebs with reduced risk of early postoperative hypotony: bleb needling combined with transconjunctival sutures tightening the scleral flap directly. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157320PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912104PMC
July 2017
34 Reads

Management of Different Subtypes of Primary Angle Closure with Phacoemulsification and Viscogoniosynechialysis.

Semin Ophthalmol 2017 18;32(4):496-500. Epub 2016 May 18.

a Department of Ophthalmology , Shanghai Aier Eye Hospital , Shanghai , China.

Purpose: To retrospectively assess the effectiveness of combined phacoemulsification with viscogoniosynechialysis for patients with different subtypes of primary angle closure (PAC).

Methods: Forty-three eyes of 37 patients diagnosed with PAC (12 eyes), PAC with glaucoma (PACG, 20 eyes), and acute PAC (11 eyes) were treated with phacoemulsification and viscogoniosynechialysis between November 2010 and October 2012. Main outcome measures were anterior chamber depth (ACD), intraocular pressure (IOP), the number of IOP-lowering medication, extent of peripheral anterior synechia (PAS), and visual acuity preoperatively and one month postoperatively. Read More

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https://www.tandfonline.com/doi/full/10.3109/08820538.2015.1
Publisher Site
http://dx.doi.org/10.3109/08820538.2015.1123730DOI Listing
October 2017
10 Reads

[Glaucoma treatment].

Authors:
Elisa Bluwol

Rev Prat 2016 05;66(5):508-513

Institut du glaucome, hôpital Saint-Joseph, Paris, France.

Glaucomas treatment. Glaucoma is the first cause of blindness in Europe. The purposes of its treatment are lowering intraocular pressure (IOP), but also getting a good patient compliance with a good tolerance and a good ratio cost/effectiveness. Read More

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May 2016
11 Reads

Lens Extraction for Management of Coexisting Cataract and Post-filtering Surgery Ocular Hypotony.

J Ophthalmic Vis Res 2015 Oct-Dec;10(4):385-90

Department of Ophthalmology, Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: To evaluate the safety and efficacy of phacoemulsification for management of post-filtering ocular hypotony.

Methods: This prospective interventional case series study recruited 21 consecutive patients with an established diagnosis of ocular hypotony with or without maculopathy. Clear corneal incision phacoemulsification was done for all patients. Read More

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http://dx.doi.org/10.4103/2008-322X.176908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795387PMC
April 2016
8 Reads