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Nepal J Ophthalmol 2021 Jan;13(25):98-103

Gandaki Medical College Teaching Hospital and Research Centre, Pokhara, Nepal.

Background: To determine the clinical profile and causes of various types of secondary glaucoma.

Materials And Methods: This was a hospital-based cross-sectional study conducted in a tertiary eye hospital of eastern Nepal from 1st June to 30th November, 2017. Patients who met the criteria for secondary glaucoma underwent detailed ophthalmic examination. Read More

PLoS One 2021 21;16(4):e0249945. Epub 2021 Apr 21.

Glaucoma Services, LV Prasad Eye Institute, Bhubaneswar, India.

Purpose: To evaluate changes in central corneal thickness (CCT) following vitrectomy.

Methods: All consecutive old and new patients referred to glaucoma services for possible secondary glaucoma after vitrectomy and who had undergone corneal pachymetry between July 2013 to June 2020, were included. The eye that developed elevated intraocular pressure (IOP) and was diagnosed clinically as glaucoma after vitrectomy, was labelled as the "affected" eye. Read More

Oman J Ophthalmol 2020 Sep-Dec;13(3):173-175. Epub 2020 Nov 2.

Cornea Department, Arasan Eye Hospital, Erode, Tamil Nadu, India.

Silicone oil (SO) is a commonly used tamponading agent in retinal detachment surgeries. Inadvertent anterior migration of SO and complete anterior chamber (AC) oil fill in an aphakic or pseudophakic eye is occasionally encountered. This can cause secondary glaucoma with very high intraocular pressure and pain. Read More

Ann Transl Med 2020 Nov;8(22):1545

INSERM UMRS 1138, Team 17, From Physiopathology of Ocular Diseases to Clinical Development, Université Sorbonne Paris Cité, Centre de Recherche des Cordeliers, Paris, France.

Congenital cataract is a rare eye disease, one of the leading treatable causes of low vision in children worldwide. Hereditary cataracts can be divided in syndromic and non-syndromic cataracts. Early diagnosis in congenital cataracts is key to reach good visual function. Read More

Cornea 2020 Nov;39(11):1359-1365

School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, Zhejiang, China; and.

Purpose: To evaluate changes in central corneal thickness (CCT) and intraocular pressure (IOP) in children after surgery for congenital cataracts and to investigate the association between CCT and IOP.

Methods: For this prospective observational cohort study, we recruited patients undergoing surgery for unilateral or bilateral congenital cataracts. CCT and IOP were measured before surgery and 1, 3, 6, 12, and 24 months after surgery. Read More

Eye (Lond) 2021 Jun 21;35(6):1637-1643. Epub 2020 Aug 21.

Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Cairo, Egypt.

Purpose: The management of glaucoma following cataract surgery (GFCS) in children is challenging. This study looks at the results of two-site trabeculotomy in paediatric aphakic/pseudophakic glaucoma, 1-year post operatively.

Methods: This prospective, institutional study was performed on 33 eyes with GFCS in patients aged ≤14 years. Read More

J Glaucoma 2020 10;29(10):e116-e119

Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham.

Gonioscopy-assisted transluminal trabeculotomy (GATT) is a minimally invasive ab interno procedure, performed with guidance of an illuminating microcatheter device (iTrack). The pathophysiology of raised intraocular pressure (IOP) in uveitic glaucoma is commonly due to increased resistance at the trabecular meshwork-Schlemm canal. By removing this resistance, GATT can potentially control the IOP. Read More

Graefes Arch Clin Exp Ophthalmol 2021 Jan 17;259(1):213-221. Epub 2020 Aug 17.

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Purpose: To study the complications and surgical outcomes of cataract surgery in patients of persistent fetal vasculature (PFV) with cataract.

Methods: In this prospective study, phacoaspiration with/without intraocular lens implantation (IOL) was done in 20 children (mean age 14.2 months) with unilateral cataract with anterior (n = 6) or combined (n = 14) PFV. Read More

Medwave 2020 Jul 22;20(6):e7965. Epub 2020 Jul 22.

Proyecto Epistemonikos, Santiago, Chile; Departamento de Oftalmología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: Cataract surgery increases the risk for rhegmatogenous retinal detachment. Pars plana vitrectomy and scleral buckling are two surgical procedures used for its repair. The combination of both techniques had been proposed for rhegmatogenous retinal detachment in patients with previous cataract surgery (pseudophakic or aphakic), but its effectiveness remains unclear. Read More

Br J Ophthalmol 2020 08 12;104(8):1040-1044. Epub 2020 Jun 12.

University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada

Background: Of the side effects of prostaglandin analogues (PGAs), uveitis and cystoid macular oedema (CME) have significant potential for vision loss based on postmarket reports. Caution has been advised due to concerns of macular oedema and uveitis. In this report, we researched and summarised the original data suggesting these effects and determined their incidence. Read More

Med J Armed Forces India 2020 Apr 15;76(2):166-171. Epub 2019 Apr 15.

Senior Advisor (Ophthalmology), Command Hospital (Air Force), Bengaluru, India.

Background: Endothelial keratoplasties have become the surgical procedure of choice over full thickness penetrating keratoplasty for corneal decompensation because of endothelial dysfunction.

Methods: A retrospective data review was performed from February 2016 to April 2017 for all the patients who underwent endothelial keratoplasty in a tertiary care center for Indian Armed Forces.

Results: A total of 161 corneal transplants were performed; endothelial keratoplasties accounted for 34 (21. Read More

Eur J Ophthalmol 2020 Sep 14;30(5):1179-1184. Epub 2020 Apr 14.

Department of Ophthalmology, Kasr Al Ainy Hospital, Cairo University, Giza, Egypt.

Purpose: To evaluate the safety and efficacy of a novel approach to implant Ex-Press mini shunt via the pars plana under a scleral flap in pseudophakic or aphakic, vitrectomized patients with secondary refractory glaucoma.

Methods: A prospective interventional case series of three patients with secondary glaucoma after pars plana vitrectomy. Intraocular pressure was not controlled by silicone oil removal, if the patient was siliconized, nor the maximum medical treatment. Read More

Ophthalmology 2020 04 9;127(4):501-510. Epub 2019 Nov 9.

Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia; Departments of Ophthalmology and Pediatrics, Stanford University School of Medicine, Palo Alto, California.

Purpose: To evaluate outcomes of bilateral cataract surgery in infants 1 to 7 months of age performed by Infant Aphakia Treatment Study (IATS) investigators during IATS recruitment and to compare them with IATS unilateral outcomes.

Design: Retrospective case series review at 10 IATS sites.

Participants: The Toddler Aphakia and Pseudophakia Study (TAPS) is a registry of children treated by surgeons who participated in the IATS. Read More

JAMA Ophthalmol 2020 01;138(1):71-75

Flaum Eye Institute, University of Rochester Medical Center, Rochester, New York.

Importance: Glaucoma can occur following cataract removal in children, and determining the risk for and factors associated with glaucoma and glaucoma suspect in a large cohort of children after lensectomy can guide clinical practice.

Objective: To estimate the incidence of glaucoma and glaucoma suspect and describe its management in the first year following lensectomy in children before 13 years of age.

Design, Setting, And Participants: A multicenter clinical research registry containing data for 1361 eyes of 994 children who underwent unilateral or bilateral lensectomy between June 2012 and July 2015 at 1 of 61 sites in the United States (n = 57), Canada (n = 3), and the United Kingdom (n = 1). Read More

Am J Ophthalmol 2020 02 10;210:158-166. Epub 2019 Oct 10.

Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Mannheim, Germany. Electronic address:

Purpose: To assess the prevalence of pseudoexfoliation (PEX) and its associations in a Russian population.

Design: Population-based cross-sectional study.

Methods: Setting: Ufa capital of Bashkortostan, Russia and a rural region in Bashkortostan. Read More

Int Ophthalmol 2020 Feb 29;40(2):313-323. Epub 2019 Sep 29.

Department of Ophthalmology Hospital Abente y Lago, Complexo Hospitalario Universitario A Coruña, Plaza del Parrote s/n, 15006, A Coruña, Spain.

Purpose: To evaluate the causes of IOL explantation, techniques for secondary IOL implantation, visual outcomes and complications.

Methods: Setting: Department of Ophthalmology Complexo Hospitalario Universitario A Coruña, Spain.

Design: Retrospective study. Read More

Acta Ophthalmol 2019 Dec 6;97(8):744-751. Epub 2019 Aug 6.

Glaucoma Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Cyclodialysis is a rare occurrence and is difficult to treat, it being concealed behind the iris. In view of the varied success outcomes of the different available surgical repair techniques, there is at present no clear consensus regarding their management strategies. Through this article, we intend to appraise the established surgical methods, update the novel techniques in vogue, discuss their outcomes and propose a uniform system to codify these corrective techniques. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Nov 30;257(11):2547-2558. Epub 2019 Jul 30.

Instituto de Microcirugía Ocular (IMO), C/ Josep María Lladó 3, 08035, Barcelona, Spain.

Purpose: To evaluate the effectiveness of temporary keratoprosthesis combined with vitreoretinal surgery and penetrating keratoplasty in patients with or without trauma.

Methods: This retrospective study included 49 eyes in 49 non-trauma patients and 51 eyes in 48 ocular trauma patients who underwent penetrating keratoplasty and vitreoretinal surgery with Eckardt temporary keratoprosthesis between 2009 and 2016, with a follow-up of at least 12 months. Study variables included previous corneal, glaucoma, or retinal surgeries; various intraoperative surgical maneuvers; lens status; vitreoretinal and corneal pathology; functional outcomes; anatomical retinal reattachment; graft clarity; and need for glaucoma surgery or treatment. Read More

Eur J Ophthalmol 2020 Nov 17;30(6):1370-1380. Epub 2019 Jul 17.

Temple Street Children's University Hospital, Dublin, Ireland.

Purpose: To determine the incidence, timing and risk factors for glaucoma and visual axis opacification development following surgery for congenital cataract in the first year of life.

Methods: A prospective case series of all cataract surgery performed in Temple Street Children's University Hospital over a 28-year period was conducted. A total of 93 subjects (135 eyes) were analysed. Read More

Arch Soc Esp Oftalmol (Engl Ed) 2019 Aug 17;94(8):377-383. Epub 2019 Jun 17.

Departamento de Oftalmología, Hospital Universitario La Paz, Madrid, España.

Objective: To study elevated postoperative intraocular pressure (PIOP) after paediatric cataract surgery in a reference centre and to compare the results obtained with the most relevant world literature.

Materials And Methods: A retrospective observational study was conducted, collecting information from clinical records of 99 patients (142 eyes) operated on due to unilateral or bilateral paediatric cataracts between 2000 and 2008.

Results: The proportion of eyes with PIOP≥20mmHg and bilateral cataracts was higher, 79. Read More

Cornea 2019 Sep;38(9):1069-1076

Case Western Reserve University, Department of Ophthalmology and Visual Sciences and University Hospitals Eye Institute, Cleveland, OH.

Purpose: To identify donor and recipient factors, including eye bank tissue observations, predictive of operative complications in the Cornea Preservation Time Study.

Methods: One thousand three hundred thirty study eyes undergoing Descemet stripping automated endothelial keratoplasty for Fuchs dystrophy or pseudophakic/aphakic corneal edema were randomized to receive a donor cornea with preservation time (PT) of 0 to 7 days (N = 675) or 8 to 14 days (N = 655). Donor factors included demographics, prelamellar corneal and postlamellar lenticule dissection thickness, central endothelial cell density, and tissue processing time. Read More

JAMA Ophthalmol 2019 07;137(7):817-824

Department of Ophthalmology, School of Medicine, Indiana University, Indianapolis.

Importance: Cataract is an important cause of visual impairment in children. Outcomes reported from a large clinical disease-specific registry can provide real-world estimates of visual outcomes and rates of adverse events in clinical practice.

Objective: To describe visual acuity and refractive error outcomes, as well as rates of amblyopia, glaucoma, and additional eye surgery, during the first year after lensectomy in children. Read More

Indian J Ophthalmol 2019 Apr;67(4):490-495

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.

Purpose: To evaluate the long-term outcomes of cataract surgery in children with uveitis.

Methods: Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center was done. The main outcome measures were visual acuity and postoperative complications. Read More

J AAPOS 2019 04 16;23(2):84.e1-84.e7. Epub 2019 Mar 16.

Duke University Department of Ophthalmology, Durham, North Carolina. Electronic address:

Purpose: To assess the factors associated with successful outcomes in the management of childhood glaucoma treated with endoscopic cyclophotocoagulation (ECP) as both primary and adjunctive surgery.

Methods: The medical records of consecutive children with glaucoma treated by a single surgeon at a single center over a 17-year period using ECP procedures were reviewed retrospectively. Treatment failure was defined as (1) intraocular pressure (IOP) >24 mm Hg at two consecutive examinations despite maximal medical treatment, (2) any additional glaucoma surgery, (3) sight-threatening complications, or (4) progression to no light perception visual acuity. Read More

Eur J Ophthalmol 2020 Jan 4;30(1):212-216. Epub 2019 Mar 4.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

A new technique of correcting tube-corneal touch is described in a case of Ahmed glaucoma valve implantation. This technique repositions the intracameral tube without externalization unlike the standard procedures which aim to correct tube-corneal touch. The technique makes use of a transscleral supracapsular anchor suture to facilitate repositioning of the tube within the ciliary sulcus. Read More

Vet Ophthalmol 2019 May 6;22(3):360-367. Epub 2019 Feb 6.

Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee.

Objective: To determine long-term outcome of phacoemulsification in raptors at the University of Tennessee Veterinary Medical Center.

Animals Studied: Seven nonreleasable diurnal raptors including, four bald eagles (Haliaeetus leucocephalus), two red-tailed hawks (Buteo jamaicensis), and one peregrine falcon (Falco peregrinus) that had undergone phacoemulsification. All birds showed behavioral changes attributable to visual deficits prior to surgery. Read More

J AAPOS 2018 06 27;22(3):188-191. Epub 2018 Apr 27.

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis.

Purpose: To report the long-term efficacy of endoscopic cyclophotocoagulation (ECP) in pediatric glaucoma following cataract surgery (GFCS).

Methods: ECP was performed on 35 eyes of 25 patients <16 years of age with GFCS. Patients were followed for a minimum of 2 years. Read More

Int J Ophthalmol 2018 18;11(2):240-244. Epub 2018 Feb 18.

Department of Ophthalmology, University of Athens, General Hospital of Athens, Mesogion 154 Ave, Athens 11527, Greece.

Aim: To estimate the efficacy and safety of the Ahmed implant in patients with high risk for failure after glaucoma surgery.

Methods: In 342 eyes of 342 patients with refractory glaucoma, even with application of medical treatment, the Ahmed valve was introduced for intraocular pressure (IOP) control, in the period of the last 20y. The nature of glaucoma was neovascular in 162 eyes, pseudophakic or aphakic in 49 eyes, inflammatory in 29 eyes and non working previous antiglaucomatic surgical interventions in 102 eyes. Read More

Acta Clin Croat 2016 09;55(3):483-489

Andrija Štampar School of Public Health, School of Medicine, University of Zagreb, Zagreb, Croatia

The purpose of this study was to assess the prevalence of pseudoexfoliation syndrome and pseudoexfoliation glaucoma and to evaluate its association with open-angle glaucoma in patients attending the Department of Ophthalmology, Dr Tomislav Bardek General Hospital in Koprivnica, northwestern Croatia. This prospective study was conducted at Dr Tomislav Bardek General Hospital between December 2012 and October 2013. A total of 5349 subjects aged 40 or above presenting for general ophthalmic examination were screened for pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Read More

J Cataract Refract Surg 2016 12;42(12):1768-1773

From the Department of Ophthalmology (Lambert, DuBois) and the School of Medicine and Biostatistics and Bioinformatics (Cotsonis), Rollins School of Public Health, Emory University, Atlanta, Georgia, the Storm Eye Institute (Wilson), Medical University of South Carolina, Charleston, South Carolina, Glick Eye Institute (Plager), Indiana University, Indianapolis, Indiana, the Department of Ophthalmology, (Buckley), Duke University, Durham, North Carolina, the Department of Ophthalmology, Naval Medical Center, San Diego, and Loma Linda University Medical Center (McClatchey), Loma Linda, California, and the Uniformed Services University of Health Sciences (McClatchey), Bethesda, Maryland, USA.

Purpose: To compare the rate of refractive growth (RRG) between aphakic eyes and pseudophakic eyes in the Infant Aphakia Treatment Study (IATS).

Setting: Twelve clinical sites across the United States.

Design: Randomized clinical trial. Read More