655 results match your criteria Glaucoma Angle Closure Chronic


Surgical management of raised intra-ocular tension in the hostile ocular surface - recurrent tube erosion in a patient with systemic sclerosis: a case report.

BMC Ophthalmol 2018 Sep 14;18(Suppl 1):222. Epub 2018 Sep 14.

Western Eye Hospital, London, UK.

Background: The surgical management of patients with uncontrolled glaucoma and scleroderma is challenging, as the hostile ocular surface poses a challenge to surgery. A serious complication is tube erosion, with the risk of subsequent endophthalmitis. Here, we present a novel technique of harvesting autologous tissue to successfully manage recurrent tube extrusion. Read More

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http://dx.doi.org/10.1186/s12886-018-0856-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157120PMC
September 2018
2 Reads

Argon laser peripheral iridoplasty for chronic primary angle-closure and angle-closure glaucoma in caucasians.

Acta Ophthalmol 2018 Sep 21. Epub 2018 Sep 21.

Department of Ophthalmology, Medical Faculty Carl Gustav Carus, Technische Universität, Dresden, Germany.

Purpose: To investigate whether the peripheral thinning and shrinking of the iris as induced with Argon laser peripheral iridoplasty (ALPI) has an effect on intraocular pressure (IOP), angle structure and 3-D anterior segment (AS) morphology in Caucasians with chronic primary angle-closure (PAC) and primary angle-closure glaucoma (PACG).

Methods: Twenty-four eyes of 24 patients (age 67.7 ± 8. Read More

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http://dx.doi.org/10.1111/aos.13878DOI Listing
September 2018

Profile and management outcomes of glaucoma cases at Qassim University Hospital.

Int J Health Sci (Qassim) 2018 Sep-Oct;12(5):20-24

Department of Ophthalmology, King Saud University, Riyadh, Saudi Arabia.

Objective: In view of the paucity of community-based data about glaucoma in Saudi Arabia, better planning to address visual disabilities due to glaucoma is a challenge. Providing hospital-based data from semi-urban places will complement the picture based on information of tertiary eye hospitals of capital.

Methods: This is one-armed cohort study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124836PMC
September 2018
1 Read

Risk factors for flat anterior chamber after glaucoma filtration surgery.

Int J Ophthalmol 2018 18;11(8):1322-1329. Epub 2018 Aug 18.

Department of Ophthalmology, the Third Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China.

Aim: To investigate the incidence rate and risk factors for grade III flat anterior chamber (FAC) after glaucoma filtration surgery based on 5-year data.

Methods: Patients who underwent glaucoma filtration surgery in Daping hospital from January 2009 to December 2013 were enrolled in this retrospective study. The incidence of grade III FAC following glaucoma filtration surgery was determined. Read More

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http://dx.doi.org/10.18240/ijo.2018.08.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090123PMC
August 2018
2 Reads
0.500 Impact Factor

Acute angle closure following hemodialysis in a 34-year-old Nigerian female.

Niger J Clin Pract 2018 Jul;21(7):942-944

Department of Medicine, University College Hospital, Ibadan, Nigeria.

Studies have reported that intraocular pressure (IOP) might change markedly during hemodialysis. We report the case of a 34-year-old Nigerian female with a 3-year history of chronic kidney disease secondary to chronic glomerulonephritis who presented with acute symptomatic elevation of IOPs following hemodialysis. She had no ocular complaints immediately before undergoing hemodialysis. Read More

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http://dx.doi.org/10.4103/njcp.njcp_358_17DOI Listing
July 2018
1 Read

Cypass Supraciliary Stent in Eye With Chronic Angle Closure and Postvitrectomy With Silicone Oil.

J Glaucoma 2018 Oct;27(10):e151-e153

El Paso Eye Surgeons, El Paso, TX.

Purpose: To report a case of successful intraocular pressure (IOP) reduction following Cypass supraciliary stent implantation in a postvitrectomized eye filled with silicone oil and chronic angle-closure glaucoma.

Materials And Methods: This is a case report.

Results: A 19-year-old female with chronic angle-closure glaucoma underwent combined cataract extraction, goniosynechiolysis and Cypass supraciliary shunt implantation. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001020DOI Listing
October 2018
2 Reads

[Blinding spontaneous suprachoroidal haemorrhage in anticoagulant taking wet-AMD patients].

Orv Hetil 2018 Jun;159(24):985-990

Szemészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Mária u. 39., 1085.

We present cases of blinding spontaneous suprachoroidal haemorrhage in anticoagulant taking wet-AMD patients. A retrospective study has been performed to present the clinical course, management and final outcome of spontaneous suprachoroidal haemorrhage in 7 eyes of six age-related macular degeneration patients seen in our clinic from January 2016 to April 2017. All patients were on chronic oral anticoagulant therapy because of cardiovascular disorder. Read More

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http://dx.doi.org/10.1556/650.2018.30966DOI Listing
June 2018
3 Reads

Systemic medication usage in glaucoma patients.

Can J Ophthalmol 2018 Jun 1;53(3):242-245. Epub 2018 Feb 1.

?>Department of Ophthalmology, Jewish General Hospital, McGill University, Montreal, Que. Electronic address:

Objective: To study the prevalence of the systemic use of some common classes of medications by glaucoma patients and their relationship to the prevalence and severity of chronic open-angle glaucoma (COAG) and primary-angle closure glaucoma (PACG).

Design: Observational prospective single-centre cross-sectional study.

Methods: Glaucoma patients or their pharmacist provided an updated list of all systemic medications that they presently use. Read More

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http://dx.doi.org/10.1016/j.jcjo.2017.10.029DOI Listing
June 2018
2 Reads

Factors Associated with Outcomes of Combined Phacoemulsification and Ahmed Glaucoma Valve Implantation.

Korean J Ophthalmol 2018 06 15;32(3):211-220. Epub 2018 May 15.

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: To evaluate outcomes and factors associated with surgical failure in patients who underwent combined phacoemulsification and Ahmed glaucoma valve (AGV) implantation.

Methods: This retrospective and longitudinal study enrolled 40 eyes (38 patients) that underwent combined phacoemulsification and AGV implantation. Visual acuity, intraocular pressure (IOP), and number of antiglaucoma medications were evaluated preoperatively and postoperatively. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3341/kjo.2017.01
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http://dx.doi.org/10.3341/kjo.2017.0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990640PMC
June 2018
1 Read

Long-term Evalution of Specular Microscopic Changes Following Nd: YAG Iridotomy in Chronic Primary Angle-closure Glaucoma Eyes.

J Glaucoma 2018 Aug;27(8):e142-e143

Dr. Shroff's Charity Eye Hospital Daryaganj, New Delhi, India.

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http://dx.doi.org/10.1097/IJG.0000000000000974DOI Listing
August 2018
4 Reads

In Reply: Long-term Evaluation of Specular Microscopic Changes Following Nd: YAG Iridotomy in Chronic Primary Angle-closure Glaucoma Eyes.

J Glaucoma 2018 Aug;27(8):e143-e144

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1097/IJG.0000000000000975DOI Listing
August 2018
2 Reads
2.430 Impact Factor

Visual Subfield Progression in Glaucoma Subtypes.

J Ophthalmol 2018 21;2018:7864219. Epub 2018 Mar 21.

Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Purpose: To investigate visual field progression pattern and factors associated with progression in patients with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and chronic angle-closure glaucoma (CACG).

Methods: The raw data of the 30-2 Humphrey Field Analyzer from glaucoma patients with definite visual field progression were processed with pointwise linear regression (PLR) analysis. The rate of change of retinal threshold sensitivity in the ten glaucoma hemifield test (GHT) zones, the upper and the lower hemifields, and the whole field was evaluated and was correlated with patients' basic demographic data. Read More

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https://www.hindawi.com/journals/joph/2018/7864219/
Publisher Site
http://dx.doi.org/10.1155/2018/7864219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883978PMC
March 2018
1 Read

Secondary Angle Closure due to Crystalline Lens Dislocation in a Patient with Atopic Dermatitis and Chronic Eye Rubbing.

Case Rep Ophthalmol 2018 Jan-Apr;9(1):197-201. Epub 2018 Mar 22.

Department of Ophthalmology, William H. Havener Eye Institute, The Ohio State University Medical Center, Columbus, Ohio, USA.

Purpose: To report an unusual case of ectopia lentis and angle closure in a patient with chronic eye rubbing.

Methods: A 57-year-old male with a history of poorly controlled atopic dermatitis presented with right eye pain, decreased vision, and an intraocular pressure (IOP) of 55 mm Hg. He had no past history of ocular disease and no reported history of trauma. Read More

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https://www.karger.com/Article/FullText/486752
Publisher Site
http://dx.doi.org/10.1159/000486752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903097PMC
March 2018
4 Reads

Refractive outcomes of phacoemulsification cataract surgery in glaucoma patients.

J Cataract Refract Surg 2018 Mar 28;44(3):348-354. Epub 2018 Mar 28.

From the Department of Ophthalmology (Manoharan, Patnaik, Bonnell, SooHoo, Pantcheva, Kahook, Wagner, Lynch, Seibold), University of Colorado School of Medicine and the Department of Biostatistics and Informatics (Wagner), University of Colorado School of Public Health, Aurora, Colorado, USA. Electronic address:

Purpose: To evaluate refractive outcomes after phacoemulsification cataract surgery in patients with glaucoma.

Setting: University of Colorado Health Eye Center, Aurora, Colorado, USA.

Design: Retrospective case series. Read More

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http://dx.doi.org/10.1016/j.jcrs.2017.12.024DOI Listing
March 2018
4 Reads

Combined Phacoemulsification and Goniosynechialysis under an Endoscope for Chronic Primary Angle-Closure Glaucoma.

J Ophthalmol 2018 8;2018:8160184. Epub 2018 Feb 8.

Department of Mechanical Engineering, University of Hong Kong, Pokfulam, Hong Kong.

Purpose: To investigate the clinical efficacy and safety of combined phacoemulsification with goniosynechialysis (GSL) under an ophthalmic endoscope for chronic primary angle-closure glaucoma and coexisting cataract.

Methods: This is a retrospective study. The intraocular pressure (IOP), best-corrected visual acuity (BCVA), and number of glaucoma medications at baseline and each postoperative follow-up visit were recorded. Read More

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http://dx.doi.org/10.1155/2018/8160184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822755PMC
February 2018
4 Reads

Macular Choroidal Small-Vessel Layer, Sattler's Layer and Haller's Layer Thicknesses: The Beijing Eye Study.

Sci Rep 2018 Mar 13;8(1):4411. Epub 2018 Mar 13.

Beijing Institute of Ophthalmology and Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

To study macular choroidal layer thickness, 3187 study participants from the population-based Beijing Eye Study underwent spectral-domain optical coherence tomography with enhanced depth imaging for thickness measurements of the macular small-vessel layer, including the choriocapillaris, medium-sized choroidal vessel layer (Sattler's layer) and large choroidal vessel layer (Haller's layer). In multivariate analysis, greater thickness of all three choroidal layers was associated (all P < 0.05) with higher prevalence of age-related macular degeneration (AMD) (except for geographic atrophy), while it was not significantly (all P > 0. Read More

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http://dx.doi.org/10.1038/s41598-018-22745-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849687PMC
March 2018
1 Read

Retinal pigment epithelium changes in Kartagener syndrome.

Am J Ophthalmol Case Rep 2018 Jun 8;10:119-121. Epub 2018 Feb 8.

Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 900 NW 17th Avenue, Miami, FL, 33136, USA.

Purpose: We present the first case in the literature of a patient with Kartagener syndrome and ocular findings of nonexudative age-related macular degeneration.

Observations: A 55-year-old woman with Kartagener syndrome and chronic angle closure glaucoma presented for evaluation of the retina. Optos ultra-widefield imaging of the fundus showed glaucomatous cupping, drusen, and retinal pigment epithelium changes within the macular region. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834646PMC
June 2018
11 Reads

Ocular Biometry in Primary Angle-Closure Glaucoma Associated with Retinitis Pigmentosa.

J Ophthalmol 2017 31;2017:9164846. Epub 2017 Dec 31.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Background: Retinitis pigmentosa (RP) comprises a group of inherited disorders in which patients typically lose night vision in adolescence and then lose peripheral vision in young adulthood before eventually losing central vision later in life. A retrospective case-control study was performed to evaluate differences in ocular biometric parameters in primary angle-closure glaucoma (PACG) patients with and without concomitant RP to determine whether a relationship exists between PACG and RP.

Methods: We used ultrasound biomicroscopy (UBM) to measure anterior chamber depth (ACD). Read More

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http://dx.doi.org/10.1155/2017/9164846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804412PMC
December 2017
4 Reads

Differences between fellow eyes of acute and chronic primary angle closure (glaucoma): An ultrasound biomicroscopy quantitative study.

PLoS One 2018 15;13(2):e0193006. Epub 2018 Feb 15.

Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

Purpose: To compare various biometric parameters between fellow eyes of acute primary angle closure (glaucoma) [APAC(G)] and fellow eyes of chronic primary angle closure (glaucoma) [CPAC(G)].

Methods: Ultrasound biomicroscopy examinations were performed on 47 patients with unilateral APAC(G) and 41 patients with asymmetric CPAC(G) before laser peripheral iridotomy and pilocarpine treatment. Anterior chamber depth and width (ACD and ACW), lens vault (LV), iris curvature (IC), iris root distance (IRD), trabecular-ciliary process distance (TCPD), iris-ciliary process distance (ICPD), trabecular-ciliary angle (TCA), and other biometric parameters were compared between fellow eyes of APAC(G) and fellow eyes of CAPC(G). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193006PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814014PMC
April 2018
5 Reads

Acute hypotony maculopathy following the initiation of a topical aqueous suppressant in a patient with a history of panuveitis without prior filtering surgery.

Am J Ophthalmol Case Rep 2017 Sep 22;7:95-98. Epub 2017 Jun 22.

Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, 1450 San Pablo Street, Los Angeles, CA 90033, United States.

Purpose: To report a case of profound hypotony maculopathy as a complication of single-agent glaucoma therapy in a patient with a history of panuveitis without previous filtering surgery.

Observations: A 70-year old Hispanic male with a history of resolved bilateral panuveitis, chronic angle closure glaucoma, and pars plana vitrectomy was started on topical timolol 0.5% daily in the left eye for mildly elevated intraocular pressure (15 mmHg). Read More

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http://dx.doi.org/10.1016/j.ajoc.2017.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722180PMC
September 2017
10 Reads

Retrospective review on the outcome and safety of transscleral diode laser cyclophotocoagulation in refractory glaucoma in Chinese patients.

Int Ophthalmol 2017 Dec 11. Epub 2017 Dec 11.

Department of Ophthalmology, United Christian Hospital, Kwun Tong, Hong Kong.

Purpose: Transscleral cyclodiode laser cyclophotocoagulation (TSCP) is often reserved for treatment of refractory glaucoma. This retrospective study investigates the safety and efficacy of TSCP among the Chinese population.

Methods: A retrospective review was performed on electronic patient records of all patients receiving TSCP between years 2009 to year 2016. Read More

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http://dx.doi.org/10.1007/s10792-017-0782-1DOI Listing
December 2017
4 Reads

Hypertonic Saline Injection Model of Experimental Glaucoma in Rats.

Methods Mol Biol 2018 ;1695:11-21

Casey Eye Institute, Oregon Health and Science University, 3375 S.W. Terwilliger Blvd, Portland, OR, 97239, USA.

A reliable method of creating chronic elevation of intraocular pressure (IOP) in rodents is an important tool in reproducing and studying the mechanisms of optic nerve injury that occur in glaucoma. In addition, such a model could provide a valuable method for testing potential neuroprotective treatments. This paper outlines the basic methods for producing obstruction of aqueous humor outflow and IOP elevation by injecting hypertonic saline (a sclerosant) into the aqueous outflow pathway. Read More

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http://dx.doi.org/10.1007/978-1-4939-7407-8_2DOI Listing
July 2018
12 Reads

Biometric Differences between Unilateral Chronic Primary Angle Closure Glaucoma and Fellow Non-Glaucomatous Eyes.

Semin Ophthalmol 2018 29;33(5):595-601. Epub 2017 Nov 29.

a Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology , Sun Yat-Sen University , Guangzhou , China.

Purpose: To compare biometric differences between eyes with unilateral chronic primary angle-closure glaucoma (PACG) and fellow non-glaucomatous eyes in the same patient.

Methods: Clinical data and imaging records of 17 patients with unilateral PACG were retrospectively reviewed. The fellow eyes with primary angle-closure (PAC) or primary angle-closure suspected (PACS) were grouped in Group 1. Read More

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http://dx.doi.org/10.1080/08820538.2017.1375121DOI Listing
July 2018
11 Reads

Acute angle closure glaucoma - A potential blind spot in critical care.

J Intensive Care Soc 2017 Aug 3;18(3):244-246. Epub 2017 Apr 3.

Milton Keynes University Hospital, NHS Foundation Trust, Milton Keynes, UK.

We report a case of a 69-year-old gentleman who developed an acutely painful eye with loss of visual acuity whilst on the critical care unit. He was admitted three days previously with an infective exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation. In addition, he received intravenous antibiotics, steroids, nebulised bronchodilators and intravenous aminophylline, together with noradrenaline for blood pressure support. Read More

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http://dx.doi.org/10.1177/1751143717701946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665139PMC
August 2017
2 Reads

Ocular Features of Cerebro-Costo-Mandibular Syndrome.

J Glaucoma 2018 Jan;27(1):e21-e23

Royal Surrey County Hospital.

Cerebro-costo-mandibular syndrome (CCMS) is a rare hereditary disorder characterized by micrognathia, posterior rib gaps, and secondary developmental delay. Patients often require ventilation and feeding support throughout life. We describe the first reported ophthalmic findings of CCMS and propose that defects in choroidal permeability lead to chronic macular edema and refractory aqueous misdirection syndrome. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000815DOI Listing
January 2018
5 Reads

Acute and chronic fluid misdirection syndrome: pathophysiology and treatment.

Graefes Arch Clin Exp Ophthalmol 2018 Jan 6;256(1):135-154. Epub 2017 Nov 6.

Department of Ophthalmology, Medical University of Gdańsk, Gdańsk, Poland.

Purpose: To summarize our current understanding of the specific pathogenic mechanisms of the fluid misdirection syndrome and possible treatment methods.

Methods: We used the PubMed web platform to find relevant studies using the following keywords: infusion misdirection syndrome, aqueous misdirection syndrome, ciliary block, ciliovitreal block, capsular block, intraoperative fluid misdirection, subcapsular fluid entrapment, acute intraoperative rock-hard eye syndrome, positive vitreous pressure glaucoma, and malignant glaucoma. Other publications were also considered as a potential source of information when referenced in relevant articles. Read More

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http://dx.doi.org/10.1007/s00417-017-3837-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748435PMC
January 2018
3 Reads

Ocular pulse amplitude in different types of glaucoma using dynamic contour tonometry: Diagnosis and follow-up of glaucoma.

Exp Ther Med 2017 Nov 30;14(5):4148-4152. Epub 2017 Aug 30.

Department of Ophthalmology, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, Jiangsu 214000, P.R. China.

The aim of the present study was to compare the ocular pulse amplitude (OPA) in patients with different types of glaucoma using dynamic contour tonometry (DCT), to evaluate ocular and systemic factors associated with the OPA and to verify whether OPA measured by DCT is an independent predictor for glaucoma diagnosis. A total of 217 eyes of 217 participants in the following five groups were included in this cross-sectional study: Chronic angle closure glaucoma (CACG), primary open angle glaucoma, normal tension glaucoma (NTG), suspected open angle glaucoma (SOAG) and normal control (NC). The following tests were simultaneously performed during a single visit: Intra-ocular pressure (IOP), OPA, cup-to-disk (C/D) ratio, mean damage (MD) and loss variance (LV). Read More

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http://dx.doi.org/10.3892/etm.2017.5074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658696PMC
November 2017
2 Reads

Chronic and Intermittent Angle Closure Caused by In-The-Bag Capsular Tension Ring and Intraocular Lens Dislocation in Patients With Pseudoexfoliation Syndrome.

J Glaucoma 2017 Nov;26(11):1051-1055

*Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne †Department of Ophthalmology, Cantonal Hospital of Winterthur, Winterthur, Switzerland.

Purpose: A subluxation or dislocation of the intraocular lens (IOL) is a well-known complication after cataract surgery in patients with pseudoexfoliation syndrome (PEX). Capsular tension rings (CTR) are frequently used to prevent postoperative complications caused by zonular weakness. Here we present a series of 7 cases, 2 with intermittent and 5 with acute angle closure caused by a combination of PEX-associated zonular weakness and a resulting unstable capsular bag-CTR-IOL complex. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000780DOI Listing
November 2017
7 Reads

Long-term scanning laser ophthalmoscopy and perimetry in different severities of primary open and chronic angle closure glaucoma eyes.

Indian J Ophthalmol 2017 Oct;65(10):963-968

Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To determine rate of change over time on scanning laser ophthalmoscopy, HRT, compared to perimetry, and to determine incidence, parametric changes, and risk factors for progression in primary open angle glaucoma (POAG) and chronic primary angle closure angle glaucoma (CPACG) eyes.

Methods: Prospective clinical study of 116 POAG eyes and 129 CPACG eyes of different severities of glaucoma. Standard automated perimetry and optic nerve head topography were studied at baseline and thereafter every 6 months. Read More

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http://dx.doi.org/10.4103/0301-4738.216734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678332PMC
October 2017
20 Reads

A Family of Early English Oculists (1600-1751), With a Reappraisal of John Thomas Woolhouse (1664-1733/1734).

Ophthalmol Eye Dis 2017 29;9:1179172117732042. Epub 2017 Sep 29.

Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Naples, FL, USA.

Introduction: John Thomas Woolhouse (1666-1733/1734), who practiced in Paris, was part of a family with 5 generations of English oculists. Some historians have derided him as a "charlatan" and have criticized him for adhering to the old notion that a cataract was a membrane anterior to the lens.

Methods: We reviewed treatises and digital records related to Woolhouse and his family and the handwritten notes of his 1721 lecture series at the Royal Society of Medicine. Read More

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http://dx.doi.org/10.1177/1179172117732042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624362PMC
September 2017
2 Reads

Multiplex Cytokine Analysis of Aqueous Humor from the Patients with Chronic Primary Angle Closure Glaucoma.

Curr Eye Res 2017 12 22;42(12):1608-1613. Epub 2017 Sep 22.

a Department of Genetics , Aravind Medical Research Foundation , Madurai , Tamil Nadu , India.

Purpose: To compare the levels of cytokines and growth factor in aqueous humor of the patients with chronic primary angle closure glaucoma (PACG) and cataract.

Methods: Aqueous humor samples were collected from 19 chronic PACG patients and compared with 14 nonglaucomatous controls presenting for cataract surgery. The levels of 27 cytokines and growth factors were measured in the aqueous samples using multiplex bead immunoassay and compared across groups. Read More

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http://dx.doi.org/10.1080/02713683.2017.1362003DOI Listing
December 2017
27 Reads

Glaucoma Surgery in Scleromalacia: Using Endoscopic Cyclophotocoagulation where Conventional Filtration Surgery or Angle Procedures are contraindicated.

J Curr Glaucoma Pract 2017 May-Aug;11(2):73-75. Epub 2017 Aug 5.

Consultant, Department of Ophthalmology, St Thomas' Hospital, London United Kingdom.

Aim: To describe the surgical management of glaucoma in a patient with severe scleromalacia, and secondary angle closure.

Introduction: The management of glaucoma with coexisting scleromalacia plus secondary angle closure is challenging as most commonly performed incisional glaucoma surgery as well as minimally invasive glaucoma surgery (MIGS), which targets the drainage angle are all contraindicated.

Case Report: Medically refractory glaucoma in a 60-year-old male with a 30-year history of granulomatosis with polyangiitis resulting in extensive severe scleromalacia, cicatricial lower lid retraction with significant conjunctival exposure, and widespread synechial angle closure from chronic anterior uveitis was managed with combined phacoemulsification cataract surgery, and endoscopic cyclophotocoagulation (ECP). Read More

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http://dx.doi.org/10.5005/jp-journals-10028-1227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577124PMC
August 2017
24 Reads

Optic Nerve Head Characteristics in Chronic Angle Closure Glaucoma Detected by Swept-Source OCT.

Curr Eye Res 2017 11 18;42(11):1450-1457. Epub 2017 Sep 18.

b Department of Ophthalmology , Massachusetts Eye and Ear, Harvard Medical School , Boston , MA , USA.

Purpose: To compare structural features in prelaminar and laminar tissues of the optic nerve head (ONH) in chronic angle closure glaucoma (CACG), primary open angle glaucoma (POAG), and control subjects.

Materials And Methods: ONH imaging was performed using swept-source optical coherence tomography (SS-OCT) for measurements of minimum rim width at Bruch's membrane opening (BMO-MRW), horizontal, and vertical lamina cribrosa depth (LCD). Prelaminar defects, categorized as hole and wedge, and lamina cribrosa (LC) defects were identified. Read More

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http://dx.doi.org/10.1080/02713683.2017.1341535DOI Listing
November 2017
7 Reads

Peripapillary retinal splitting visualized on OCT in glaucoma and glaucoma suspect patients.

PLoS One 2017 23;12(8):e0182816. Epub 2017 Aug 23.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

Purpose: To identify the risk factors for development of peripapillary retinal splitting (schisis) in patients with glaucoma or suspicion of glaucoma.

Setting: Glaucoma Clinic, Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Methods: In this institutional cross-sectional study, 495 patients (990 eyes) who had undergone spectral-domain optical coherence tomography (OCT Spectralis HRA-OCT, Heidelberg Engineering) optic nerve head (ONH) imaging and did not have identifiable optic nerve pits, pseudopits or coloboma were included. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182816PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568282PMC
October 2017
12 Reads

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.

Invest Ophthalmol Vis Sci 2017 08;58(10):4384–4389

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

Purpose: This study evaluates the associations of haplotype-tagging single nucleotide polymorphisms (SNPs) in the PARL-ABCC5-HTR3D-HTR3C region with primary angle closure glaucoma (PACG), with a view to identify the responsible SNP in this region.

Methods: Thirty SNPs from the PARL-ABCC5-HTR3D-HTR3C region were genotyped in a Hong Kong Chinese cohort of 422 PACG patients and 400 control subjects, using TaqMan SNP genotyping assays. Single marker and haplotype-based association analyses were performed. Read More

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http://dx.doi.org/10.1167/iovs.17-22304DOI Listing
August 2017
14 Reads
3.404 Impact Factor

Long-Term Evaluation of Specular Microscopic Changes Following Nd: YAG Iridotomy in Chronic Primary Angle-Closure Glaucoma Eyes.

J Glaucoma 2017 Sep;26(9):762-766

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Aim: The aim of this study was to evaluate specular microscopy of chronic primary angle-closure glaucoma (CPACG) eyes at least 1 year after Nd:YAG iridotomy, and compare them with CPACG eyes without an iridotomy and age-matched, normal eyes.

Patients And Method: Consecutive patients of CPACG at the Glaucoma service were screened. All patients underwent slit-lamp biomicroscopy, +90 D examination, and applanation tonometry. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000704DOI Listing
September 2017
16 Reads
2.430 Impact Factor

Increased aquaporin-1 levels in lens epithelial cells with primary angle-closure glaucoma.

Int J Ophthalmol 2017 18;10(7):1101-1105. Epub 2017 Jul 18.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.

Aim: To determine the levels of aquaporin-1 (AQP-1) in the lens epithelial cells (LECs) of primary glaucoma and to clarify its correlation with lens thickness.

Methods: This study comprised 64 eyes of 64 patients with primary glaucoma, who were divided into 3 groups: 25 eyes of 25 patients with acute primary angle-closure glaucoma (APACG), 19 eyes of 19 patients with chronic primary angle-closure glaucoma (CPACG) and 20 eyes of 20 patients with primary open angle glaucoma (POAG). This study also included 12 eyes of 12 patients with senile cataract as controls. Read More

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http://dx.doi.org/10.18240/ijo.2017.07.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514272PMC
July 2017
9 Reads

Analyzing cytokines as biomarkers to evaluate severity of glaucoma.

Int J Ophthalmol 2017 18;10(6):925-930. Epub 2017 Jun 18.

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China.

Aim: To analyze cytokines as biomarkers for evaluation of severity of glaucoma.

Methods: This was a prospective case-control study including 29 eyes with glaucoma. Besides, 28 eyes with senile cataract were used as control. Read More

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http://dx.doi.org/10.18240/ijo.2017.06.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515140PMC
June 2017
3 Reads

Long-term outcomes after acute primary angle closure of Caucasian chronic angle closure glaucoma patients.

Clin Exp Ophthalmol 2018 Apr 22;46(3):232-239. Epub 2017 Sep 22.

Singapore National Eye Center, Singapore, Singapore.

Importance: There is a lack of information about long-term results of chronic angle closure glaucoma following an acute primary angle closure attack in Caucasian patients.

Purpose: The aim of the study was to report morphological and functional long-term data of chronic angle closure eyes following a monolateral primary angle closure attack and to provide a comparison with their fellow eyes.

Design: Observational retrospective case series. Read More

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http://doi.wiley.com/10.1111/ceo.13024
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http://dx.doi.org/10.1111/ceo.13024DOI Listing
April 2018
21 Reads

Angle closure as a cause for intermittent headache in a child.

BMJ Case Rep 2017 Jun 13;2017. Epub 2017 Jun 13.

Visual Sciences Study Center, Faculty of Medicine of Lisbon University, Lisbon, Portugal.

Angle closure is usually associated with older patients, as it typically manifests in middle to later life, being associated with an age-related increased lens volume. However, angle closure can occur in any age group if there is an anatomical predisposition that promotes pupillary block or an anterior pulling of the iris. During an acute angle closure, patients generally experience ocular pain, headache, nausea, vomiting and conjunctival hyperaemia. Read More

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http://dx.doi.org/10.1136/bcr-2017-219517DOI Listing
June 2017
6 Reads

Glaucoma.

Lancet 2017 Nov 31;390(10108):2183-2193. Epub 2017 May 31.

Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany.

Glaucoma is a heterogeneous group of diseases characterised by cupping of the optic nerve head and visual-field damage. It is the most frequent cause of irreversible blindness worldwide. Progression usually stops if the intraocular pressure is lowered by 30-50% from baseline. Read More

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http://dx.doi.org/10.1016/S0140-6736(17)31469-1DOI Listing
November 2017
9 Reads

Dynamic changes of anterior segment in patients with different stages of primary angle-closure in both eyes and normal subjects.

PLoS One 2017 18;12(5):e0177769. Epub 2017 May 18.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Purpose: To compare changes in anterior segment parameters under light and dark (light-to-dark) conditions among eyes with chronic primary angle-closure glaucoma (CPACG), fellow eyes with confirmed or suspect primary angle-closure (PAC or PACS), and age-matched healthy eyes.

Methods: Consecutive patients with CPACG in one eye and PAC/PACS in the fellow eye, as well as age-matched healthy subjects were recruited. Anterior segment optical coherence tomography measurements were conducted under light and dark conditions, and anterior chamber, lens, and iris parameters compared. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177769PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436810PMC
September 2017
30 Reads

RETINAL AND CHOROIDAL VASCULAR OCCLUSION FOLLOWING AQUEOUS MISDIRECTION SYNDROME IN A PATIENT WITH SICKLE CELL TRAIT.

Retin Cases Brief Rep 2017 May 9. Epub 2017 May 9.

Department of Ophthalmology, School of Medicine, Wayne State University, Kresge Eye Institute, Detroit, Michigan.

Purpose: To report a patient with retinal and choroidal vascular occlusion as a presenting sign of sickle cell trait following the development of aqueous misdirection syndrome.

Methods: Retrospective chart review.

Results: A patient treated for bilateral chronic angle-closure glaucoma with sequential EX-PRESS glaucoma filtration device surgery developed sequential bilateral aqueous misdirection syndrome. Read More

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http://Insights.ovid.com/crossref?an=01271216-900000000-9898
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http://dx.doi.org/10.1097/ICB.0000000000000590DOI Listing
May 2017
17 Reads

Intraoperative Optical Coherence Tomography-Assisted Descemet Stripping Automated Endothelial Keratoplasty for Anterior Chamber Fibrous Ingrowth.

Cornea 2017 Jun;36(6):757-758

UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA.

Purpose: Here, we present the first reported case of intraoperative optical coherence tomography (OCT)-assisted Descemet membrane stripping automated endothelial keratoplasty (DSAEK) in a patient with anterior segment fibrous ingrowth.

Methods: A 61-year-old woman with corneal edema and chronic angle-closure glaucoma secondary to fibrous ingrowth after 2 glaucoma shunt device implantations underwent dissection and removal of anterior chamber fibrous ingrowth and DSAEK. The surgical techniques using intraoperative OCT and outcome are described. Read More

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http://Insights.ovid.com/crossref?an=00003226-201706000-0002
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http://dx.doi.org/10.1097/ICO.0000000000001192DOI Listing
June 2017
10 Reads

Ocular Emergencies: Red Eye.

Med Clin North Am 2017 May 8;101(3):615-639. Epub 2017 Mar 8.

Division of Comprehensive Eye Care, Wilmer Eye Institute, Johns Hopkins University School of Medicine, 400 North Broadway, Suite 4001, Baltimore, MD 21231, USA. Electronic address:

"Red eye" is used as a general term to describe irritated or bloodshot eyes. It is a recognizable sign of an acute/chronic, localized/systemic underlying inflammatory condition. Conjunctival injection is most commonly caused by dryness, allergy, visual fatigue, contact lens overwear, and local infections. Read More

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http://dx.doi.org/10.1016/j.mcna.2016.12.013DOI Listing
May 2017
2 Reads

High intensity focused ultrasound as first line treatment in patients with chronic angle closure glaucoma at risk for malignant glaucoma.

J Fr Ophtalmol 2017 Apr 23;40(4):264-269. Epub 2017 Mar 23.

Ophthalmology department, Institut du glaucome, university Paris-Descartes, centre hospitalier Paris-Saint-Joseph, 185, rue Raymond-Losserand, 75674 Paris cedex 14, France.

Purpose: Evaluation of high intensity focused ultrasound (HIFU) transscleral cyclocoagulation as an alternative to trabeculectomy in the treatment of refractory chronic angle closure glaucoma (CACG).

Methods: This prospective one armed single center pilot study was conducted on patients with medically uncontrolled CACG who underwent high intensity focused ultrasound (HIFU) cyclocoagulation as first line surgical treatment, using the Eye-OP1 HIFU device (Eyetechcare-Rillieux-la-Pape, France) driven by ultrasound biomicroscopic (UBM) ciliary body localization. All patients had documented progression of their glaucoma despite conventional medical and laser therapy. Read More

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http://dx.doi.org/10.1016/j.jfo.2016.10.013DOI Listing
April 2017
16 Reads

Idiopathic Bilateral Profound Hypotony in an Unknown Progressive Neurodegenerative Disorder.

J Glaucoma 2017 May;26(5):e168-e170

Department of Ophthalmology and Visual Sciences, The University of Iowa Hospitals and Clinics, Iowa City, IA.

Purpose: To present a unique case of idiopathic bilateral hypotony in a patient with progressive, undiagnosed neurological decline, possibly due to mitochondrial disease, and to explore mechanisms of disease and potential treatment options.

Methods: This is a case report.

Patient: A 17-year-old boy with a history of chronic progressive bilateral vision loss and hypotony in the setting of progressive gait abnormalities, lower extremity spasticity, nystagmus, and urinary retention starting around age 8. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000639DOI Listing
May 2017
6 Reads

Long-chain unsaturated fatty acids as possible important metabolites for primary angle-closure glaucoma based on targeted metabolomic analysis.

Biomed Chromatogr 2017 Sep 26;31(9). Epub 2017 Mar 26.

Department of Clinical Laboratory, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.

Primary angle-closure glaucoma (PACG) is a severe chronic neurodegenerative disease in Asia. Identification of important metabolites associated with PACG is crucial for early intervention and advancing knowledge of the disease mechanism. We applied gas chromatography-mass spectrometry (GC-MS) for targeted metabolomic analysis on serum samples from 38 newly diagnosed PACG patients and 48 controls. Read More

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http://dx.doi.org/10.1002/bmc.3963DOI Listing
September 2017
14 Reads

Pupillary block due to reverse implantation of a sulcus intraocular lens.

JCRS Online Case Rep 2016 Aug;4(3):41-44

University of Maryland School of Medicine (Zhang) and the Department of Ophthalmology and Visual Sciences (Soni, Alexander, Kalarn, Saeedi), University of Maryland School of Medicine, Baltimore, Maryland, USA.

An 88-year-old woman with a history of complicated cataract extraction by phacoemulsification with sulcus intraocular lens (IOL) placement developed pseudophakic pupillary block after reverse implantation of the IOL. In the postoperative period, she had persistently elevated intraocular pressures (IOP) and was diagnosed with chronic angle-closure glaucoma that was treated medically. She presented 5 years later with acute pupillary block. Read More

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http://dx.doi.org/10.1016/j.jcro.2016.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293322PMC
August 2016
12 Reads