722 results match your criteria Glaucoma Angle Closure Chronic


Polypharmacy-associated potential contraindications of drug prescriptions in patients with primary angle closure disease in a real-world setting.

J Pharm Health Care Sci 2021 May 3;7(1):17. Epub 2021 May 3.

Present Address: Department of Pharmacy, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi, Chuo-ku, Kobe, 650-0047, Japan.

Background: Primary angle closure disease (PACD) is a type of glaucoma in which the intraocular pressure (IOP) is increased because of the blockage of the anterior chamber angle. Medications contraindicated for patients with PACD, such as anticholinergics, cause mydriasis, and can elevate IOP. However, anticholinergics are currently contraindicated only for primary angle closure glaucoma (PACG) in Japanese package inserts. Read More

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Glaucoma.

Med Clin North Am 2021 May 2;105(3):493-510. Epub 2021 Apr 2.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

Glaucoma is the leading cause of irreversible blindness worldwide. The global prevalence of glaucoma in people aged 40 to 80 years is estimated to be 3.5%. Read More

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Overfiltering Bleb en Route to Annular Ciliochoroidal Effusion.

Middle East Afr J Ophthalmol 2020 Oct-Dec;27(4):241-243. Epub 2021 Jan 19.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Annular ciliochoroidal effusion is a rare condition that can complicate trabeculectomy. We report a case of ciliochoroidal effusion mimicking aqueous misdirection after combined glaucoma and cataract surgery. A 75-year-old male with pseudoexfoliation, chronic angle-closure glaucoma, and advanced optic disc damage developed ciliochoroidal effusion after a combined trabeculectomy and phacoemulsification with intraocular lens implantation. Read More

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January 2021

Nationwide Glaucoma incidence in end stage renal disease patients and kidney transplant recipients.

Sci Rep 2021 Apr 1;11(1):7418. Epub 2021 Apr 1.

Department of Ophthalmology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.

Glaucoma shares common risk factors with chronic kidney disease (CKD) but previous cross-sectional studies have demonstrated discrepancies in the risk of glaucoma in CKD patients. This study enrolled kidney transplantation recipients (KTRs) (n = 10,955), end stage renal disease (ESRD) patients (n = 10,955) and healthy controls (n = 10,955) from National Health Insurance Service database of the Republic of Korea. A Cox proportional hazard regression model was used to calculate the hazard ratios (HR) for primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) incidences. Read More

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Lens extraction for chronic angle-closure glaucoma.

Cochrane Database Syst Rev 2021 03 24;3:CD005555. Epub 2021 Mar 24.

Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.

Background: Primary angle-closure glaucoma (PACG) is characterized by a rise in intraocular pressure (IOP) secondary to aqueous outflow obstruction, with relative pupillary block being the most common underlying mechanism. There is increasing evidence that lens extraction may relieve pupillary block and thereby improve IOP control. As such, comparing the effectiveness of lens extraction against other commonly used treatment modalities can help inform the decision-making process. Read More

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Laser peripheral iridoplasty for chronic angle closure.

Cochrane Database Syst Rev 2021 03 23;3:CD006746. Epub 2021 Mar 23.

Centre for Public Health, Queen's University Belfast, Belfast, UK.

Background: In at least a third of primary angle closure cases, appositional angle closure persists after laser peripheral iridotomy, and further intervention may be considered. Laser peripheral iridoplasty (LPIp) can be used in treating chronic angle closure when angle closure persists after laser peripheral iridotomy. Previous reviews have found insufficient data to determine its clinical effectiveness, compared to other interventions. Read More

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Aetiology and clinical characteristics of uveitic glaucoma in Turkish patients.

Int Ophthalmol 2021 Mar 17. Epub 2021 Mar 17.

University of Health Sciences Turkey, Beyoglu Eye Training and Research Hospital, Bereketzade Street Number: 2, Beyoglu, Istanbul, Turkey.

Purpose: To investigate the types, frequency and clinical profiles of uveitic glaucoma seen at a tertiary care center and also to have an idea about the distribution of uveitic glaucoma types in Turkish population.

Methods: Consecutive case notes of all patients attending a specialized uveitis clinic over a 3-month period were reviewed retrospectively.

Results: One hundred and seven eyes of 96 patients were included. Read More

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Outcomes of Small Size Ahmed Glaucoma Valve Implantation in Asian Chronic Angle-Closure Glaucoma.

J Clin Med 2021 Feb 17;10(4). Epub 2021 Feb 17.

Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.

For chronic angle-closure glaucoma (ACG), Ahmed glaucoma valve (AGV) is a useful drainage device for intraocular pressure (IOP) control but there are few reports discussing the outcomes of small size AGV in adult patients. This retrospective study involved 43 Asian adult patients (43 eyes) with chronic ACG. All patients had undergone small size AGV insertion and were divided into anterior chamber (AC) group and posterior chamber (PC) group. Read More

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February 2021

Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer.

BMJ Case Rep 2021 Feb 23;14(2). Epub 2021 Feb 23.

Ophthalmology, Epsom and Saint Helier Hospital NHS Trust, Carshalton, Sutton, UK.

In this case study, we explore a case of bilateral acute angle closure (AAC) attack detected in a 52-year-old female patient with no other ophthalmic background or predisposition to angle closure, following an increase of her regular sumatriptan dose used for migraine relief. Even though the initial presentation was misinterpreted as migraine attack, it nevertheless alerted the treating physicians to immediate cessation of the drug, allowing for the pertinent ocular symptomatology to be unveiled. Drug-induced bilateral AAC is a rare occurrence and can lead to significant ocular morbidity if not detected and treated early. Read More

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February 2021

Novel mechanism of decreased iris vasculature density after cosmetic iris implants.

BMJ Case Rep 2021 Feb 4;14(2). Epub 2021 Feb 4.

Cleveland Clinic Cole Eye Institute, Cleveland, Ohio, USA.

A 25-year-old man presented with decreased vision in both eyes, approximately 4 years following bilateral bright ocular cosmetic iris implantation. On examination, he was found to have bilateral elevated intraocular pressures, anterior chamber cells and flare, chronic peripheral anterior synechiae and significantly reduced endothelial cell counts. Ultrasound biomicroscopy demonstrated compression of the peripheral iris, resulting in synechial angle closure in both eyes. Read More

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February 2021

Glaucoma in Adults-Screening, Diagnosis, and Management: A Review.

JAMA 2021 01;325(2):164-174

W.K. Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor.

Importance: Glaucoma is the most common cause of irreversible blindness worldwide. Many patients with glaucoma are asymptomatic early in the disease course. Primary care clinicians should know which patients to refer to an eye care professional for a complete eye examination to check for signs of glaucoma and to determine what systemic conditions or medications can increase a patient's risk of glaucoma. Read More

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January 2021

Postoperative complicated peripheral cortical cataract after ultrasound cycloplasty: a case report.

BMC Ophthalmol 2021 Jan 7;21(1):16. Epub 2021 Jan 7.

Chongqing Aier Eye Hospital, No.2, Huatang Road, Jiangbei District, Chongqing, China.

Background: Ultrasound cycloplasty (UCP) is a non-invasive procedure for glaucoma treatment. Using high-intensity focused ultrasound to work on the ciliary body, the generation of aqueous humor can be reduced and the drainage of aqueous humor through the uveoscleral pathway can be enhanced. Recently, this therapy is gradually gaining clinical recognition. Read More

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January 2021

Bilateral Ocular Ischemic Syndrome in the Setting of Chronic Angle Closure Glaucoma.

J Glaucoma 2021 05;30(5):e262-e264

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN.

We report novel case of a 57-year-old woman who developed bilateral ocular ischemic syndrome in the setting of chronic angle closure glaucoma without associated angle neovascularization. Detailed is a course in which markedly prolonged, elevated intraocular pressure led to significantly reduced arterial perfusion at the level of the central retinal artery, leading to the clinical picture of ocular ischemic syndrome. Read More

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Outcomes of combined gonioscopy-assisted transluminal trabeculotomy and goniosynechialysis in primary angle closure: a retrospective case series.

Int Ophthalmol 2021 Apr 3;41(4):1223-1231. Epub 2021 Jan 3.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Purpose: To evaluate the additional intraocular pressure (IOP) lowering effect of gonioscopy-assisted transluminal trabeculotomy (GATT) to contemporary goniosynechialysis (GSL) in endeavouring to abolish subsequent occlusion after chronic iridotrabecular contact in primary angle closure (PAC) patients.

Methods: A retrospective case series of all PAC eyes underwent GATT + GSL with or without phacoemulsification and intraocular lens implantation (PEA + IOL) from December 2016 to May 2018 were recruited. IOP and the number of anti-glaucoma medications were compared pre- and post-operatively by Wilcoxon signed-rank test. Read More

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The return of phacoemulsification after emergency status related to COVID-19: the experience of a tertiary referral center.

J Cataract Refract Surg 2020 Nov 30. Epub 2020 Nov 30.

Ophthalmology Department of Centro Hospitalar e Universitário do Porto (CHUP), Oporto, Portugal.

Purpose: To present a protocol of priority criteria for phacoemulsification after the backlog due to SARSCOV-2 pandemic status.

Setting: Ophthalmology department of Centro Hospitalar e Universitário do Porto (CHUP), Oporto, Portugal.

Design: Cross-sectional, non-randomized, retrospective study. Read More

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November 2020

MicroPulse Transscleral Laser Therapy with Kahook Dual Blade Excisional Goniotomy and Goniosynechialysis Combined with Phacoemulsification for Angle-Closure Glaucoma: A Case Report.

Int Med Case Rep J 2020 13;13:631-636. Epub 2020 Nov 13.

Beirut Eye and ENT Specialist Hospital, Beirut, Lebanon.

Purpose: To report the efficacy and safety of MicroPulse transscleral laser therapy (TLT) and Kahook Dual Blade excisional goniotomy and goniosynechialysis combined with phacoemulsification for chronic angle-closure glaucoma (ACG).

Patients And Methods: A 39-year-old hyperopic female with a known history of ACG presented with a 2-week history of blurry vision, headache, and photophobia in the right eye (RE) following surgical peripheral iridectomy at another hospital. On examination, her uncorrected visual acuity was 20/50 in the RE, and 20/25 in the left eye (LE). Read More

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November 2020

Safety and efficacy of incisional goniotomy as an adjunct with phacoemulsification in primary angle-closure glaucoma.

J Cataract Refract Surg 2021 Apr;47(4):504-511

From the Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of incisional goniotomy as an adjunct to phacoemulsification in primary angle-closure glaucoma (PACG) patients.

Methods: Consecutive patients with PACG (high or borderline IOP) deemed fit for phacoemulsification were enrolled. After phacoemulsification, incisional goniotomy was performed with or without goniosynechialysis. Read More

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Profiles and Clinical Characteristics of Newly Diagnosed Glaucoma in Urban Korea: A Multicenter Study.

Korean J Ophthalmol 2020 10 5;34(5):353-360. Epub 2020 Oct 5.

Department of Ophthalmology, Chungnam National University Hospital, Daejeon, Korea.

Purpose: To explore the clinical characteristics and profiles of newly diagnosed glaucoma subtypes in urban Korea.

Methods: All newly diagnosed glaucoma patients enrolled in the participating ophthalmology outpatient clinics were included. A review of medical history including family history of glaucoma was conducted. Read More

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October 2020

Late Spontaneous Reabsorption of Interface Fluid after Descemet's Stripping Automated Endothelial Keratoplasty Surgery.

Case Rep Ophthalmol 2020 May-Aug;11(2):423-429. Epub 2020 Aug 6.

Department of Ophthalmology, Abbiategrasso Hospital, ASST Ovest Milanese, Abbiategrasso, Italy.

An 80-year-old male was referred to our hospital for chronic bullous keratopathy in the right eye. Ten years before, he was affected by an attack of primary acute angle closure glaucoma in high hyperopia and Fuchs' endothelial dystrophy. A bilateral iridotomy was performed. Read More

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Secondary angle-closure glaucoma as an ocular presentation of systemic lupus erythematosus: a case report.

J Int Med Res 2020 Sep;48(9):300060520959492

Shandong Provincial Qianfoshan Hospital, The First Hospital Affiliated with Shandong First Medical University, Jinan, Shandong Province, China.

Systemic lupus erythematosus (SLE) is a chronic idiopathic autoimmune disease. SLE can involve almost any part of the eyes. However, bilateral angle-closure glaucoma due to lupus choroidopathy that is accompanied by polyserositis and nephropathy is rare. Read More

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September 2020

Influence of automated visual field testing on intraocular pressure.

BMC Ophthalmol 2020 Sep 9;20(1):363. Epub 2020 Sep 9.

Quinze-Vingts National Ophthalmology Hospital, INSERM-DGOS CIC 1423, IHU FOReSIGHT, 28 rue de Charenton, 75012, Paris, France.

Background: To evaluate the influence of automated visual field (VF) testing on intraocular pressure (IOP) in patients with ocular hypertension (OHT) or glaucoma.

Methods: We conducted a prospective observational study in the glaucoma department at Quinze-Vingts National Ophthalmology Hospital in Paris. Ninety-five right eyes of 95 patients followed for glaucoma or OHT were included. Read More

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September 2020

Iridoschisis: visual outcome in treated versus untreated eye.

GMS Ophthalmol Cases 2020 26;10:Doc39. Epub 2020 Aug 26.

SUNY Downstate Medical Center, Brooklyn, New York, United States.

A 67-year-old man was referred for iris color change. He was noted to have narrow angles with atrophic iris appearance and visually significant cataracts. The iris findings were consistent with iridoschisis. Read More

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Pars plana vitrectomy combined with hyaloido-zonula-iridectomy in treatment of patients with chronic aqueous misdirection: A systematic literature review and case series.

Acta Ophthalmol 2021 May 25;99(3):251-259. Epub 2020 Aug 25.

Department of Ophthalmology, Rigshospitalet-Glostrup, Glostrup, Denmark.

Purpose: To evaluate the efficacy of vitrectomy combined with hyaloido-zonula-iridectomy from an anterior or a posterior approach in patients with treatment-resistant aqueous misdirection (chronic aqueous misdirection) by systematically reviewing existing literature in combination with presentation of a case series.

Methods: A systematic literature review was performed in PubMed, EMBASE and Cochrane Library databases using search terms: malignant glaucoma, ciliary block, ciliolenticular block and aqueous misdirection. A consecutive series of three pseudophakic patients (5 eyes) diagnosed with chronic aqueous misdirection after cataract surgery is presented. Read More

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Intraocular Pressure Changes after Cataract Surgery in Patients with and without Glaucoma: An Informatics-Based Approach.

Ophthalmol Glaucoma 2020 Sep - Oct;3(5):343-349. Epub 2020 Jun 9.

Byers Eye Institute, Stanford University, Palo Alto, California; Veterans Affairs Palo Alto Health Care System, Palo Alto, California.

Purpose: To evaluate changes in intraocular pressure (IOP) after cataract surgery among patients with or without glaucoma using automated extraction of data from electronic health records (EHRs).

Design: Retrospective cohort study.

Participants: Adults who underwent standalone cataract surgery at a single academic center from 2009-2018. Read More

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The Effectiveness and Safety of Micropulse Cyclophotocoagulation in the Treatment of Ocular Hypertension and Glaucoma.

Ophthalmol Glaucoma 2020 May - Jun;3(3):181-189. Epub 2020 Feb 28.

Uptown Eye Specialists, Vaughan, Canada; Department of Ophthalmology & Vision Sciences, University of Toronto, Toronto, Canada. Electronic address:

Purpose: To evaluate the effectiveness and safety of primary and adjunctive micropulse cyclophotocoagulation (MPCPC) in the treatment of ocular hypertension (OHT) and glaucoma.

Design: Retrospective cohort study.

Participants: Ocular hypertension and all severities of glaucoma (including treatment-naïve and well-sighted eyes) and all types of glaucoma (including normal-tension glaucoma [NTG]). Read More

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February 2020

Effect of Angle Narrowing on Sectoral Variation of Anterior Chamber Angle Width: The Chinese American Eye Study.

Ophthalmol Glaucoma 2020 Mar-Apr;3(2):130-138. Epub 2019 Dec 27.

Southern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, California.

Purpose: To characterize the relationship between mean and sectoral variation of anterior chamber angle (ACA) width using anterior segment optical coherence tomography (AS-OCT).

Methods: Subjects aged 50 years or older were identified from the Chinese American Eye Study (CHES), a population-based epidemiological study in Los Angeles, CA. Each subject underwent a complete ocular examination including gonioscopy and AS-OCT imaging. Read More

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December 2019

Optical coherence tomography angiography using the black-and-white pixel binarization histogram software: a new technique for evaluating healing of macular holes in two surgical techniques.

Int J Retina Vitreous 2020 1;6:25. Epub 2020 Jul 1.

Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.

Background: Many factors can influence the functional outcomes of macular hole surgery and some studies have tried to describe anatomical features that could predict successful treatment. The purpose of this study is to describe a new technique for evaluating the healing of macular holes after two surgical techniques using a black-and-white pixel binarization histogram software by optical coherence tomography angiography and its potential functional implications.

Methods: This was a retrospective, observational case series of patients who presented with idiopathic full-thickness macular holes and underwent vitreoretinal surgery for successful macular hole closure using the internal limiting membrane peeling technique or the inverted peeling technique or the free internal limiting membrane flap technique. Read More

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Choroidal detachment-induced secondary angle-closure after trabeculectomy in patient with ocular venous congestion: A case report.

Am J Ophthalmol Case Rep 2020 Sep 15;19:100782. Epub 2020 Jun 15.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of 
Medicine, Kyoto, Japan.

Purpose: To report a particular circumstance that led to the abnormal complication of choroidal detachment (CD)-induced secondary angle-closure after trabeculectomy with mitomycin C (MMC).

Observations: An 82-year-old Japanese male patient with underlying chronic obstructive pulmonary disease and suspicion of ocular venous congestion in both eyes whom diagnosed as primary open-angle glaucoma with uncontrolled intraocular pressure (IOP) of his left eye then underwent an uneventful trabeculectomy with MMC. After the surgery, his left eye had high IOP with a shallow anterior chamber (A/C) but the bleb was hyperfiltration. Read More

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September 2020