755 results match your criteria Glaucoma Angle Closure Chronic


Clinical profile and long term outcomes of eyes with choroidal detachment following trabeculectomy.

Indian J Ophthalmol 2022 05;70(5):1635-1641

Department of Biostatistics, Aravind Eye Hospital and Post-Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.

Purpose: To assess the long-term outcomes of choroidal detachments (CDs) in eyes following trabeculectomy.

Methods: Retrospective comparative case series. Data of patients with CDs following trabeculectomy (5-year period) with or without cataract surgery with a minimum of 3 months of follow-up were included. Read More

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Valsalva-Induced Spontaneous Suprachoroidal Hemorrhage: A Case Report and Review of the Literature.

Klin Monbl Augenheilkd 2022 Apr 26;239(4):559-564. Epub 2022 Apr 26.

Department of Ophthalmology, Jules-Gonin Eye Hospital, FAA, University of Lausanne, Lausanne, Switzerland.

We report a rare case of spontaneous suprachoroidal hemorrhage and present a systematic review of the literature using PubMed/Medline databases. Patients that developed a spontaneous suprachoroidal hemorrhage with a history of previous intraocular surgery were excluded. An 82-year-old male patient with no known ocular pathologies or surgical history was referred with acute ocular pain and decreased vision in the right eye (BCVA: 0. Read More

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Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer.

Drug Ther Bull 2022 Apr 7. Epub 2022 Apr 7.

Ophthalmology, Epsom and Saint Helier Hospital NHS Trust, Carshalton, Sutton, UK.

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Risk factors for glaucoma drainage device revision or removal using the IRIS Registry.

Am J Ophthalmol 2022 Apr 2. Epub 2022 Apr 2.

Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

Purpose: To elucidate risk factors for revision or removal of glaucoma drainage devices (GDD) in glaucoma patients in the United States.

Design: Retrospective cohort study.

Methods: IRIS® Registry (Intelligent Research in Sight) patients who underwent GDD insertion between 01/01/2013 and 12/31/2018 were included. Read More

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[Comparison study for the proportion of underdiagnosed zonulopathy in angle closure glaucoma].

Zhonghua Yan Ke Za Zhi 2022 Mar 11;58:1-10. Epub 2022 Mar 11.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing Ophthalmic Institute, Beijing 100730, China.

To analyze the proportion and clinical characteristics of underdiagnosed zonulopathy in angle closure glaucoma (ACG) patients and to explore the related risk factors. Case-control study. Continuous cases of ACG patients who underwent phacoemulsification combined with intraocular lens implantation and goniosynechialysis surgery [ACG group, including acute angle closure glaucoma (AACG) and chronic angle closure glaucoma (CACG)] from November 1, 2020 to October 31, 2021 and age-related cataract patients who underwent phacoemulsification combined with intraocular lens implantation surgery in the same period (control group) were included. Read More

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Macular pigment optical density and its determinants in a Russian population: the ural eye and medical study.

Acta Ophthalmol 2022 Mar 28. Epub 2022 Mar 28.

Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany.

Purpose: To assess the macular pigment optical density (MPOD) and its associations with ocular and systemic parameters and diseases.

Methods: The population-based study Ural Eye and Medical Study included 5899 (80.5%) out of 7328 eligible individuals. Read More

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Corneal endothelial cell density loss following glaucoma surgery alone or in combination with cataract surgery: A systematic review and meta-analysis.

Ophthalmology 2022 Mar 21. Epub 2022 Mar 21.

Topic: Corneal endothelial cell density (ECD) loss following glaucoma surgery with or without cataract surgery.

Clinical Relevance: Corneal ECD loss may occur due to intraoperative surgical trauma in glaucoma surgery or postoperatively with chronic endothelial cell trauma or irritation.

Methods: Trabeculectomy, glaucoma filtration surgery or microinvasive glaucoma surgery in participants with ocular hypertension, primary and secondary open angle glaucoma, normal tension glaucoma and angle-closure glaucoma were included. Read More

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Can hemifacial spasm lead to glaucomatous changes?

J Fr Ophtalmol 2022 May 5;45(5):504-510. Epub 2022 Mar 5.

Department of Ophthalmology, Tung Wah Eastern Hospital, 19 Eastern Hospital Road, Causeway Bay, Hong Kong.

Purpose: To evaluate the association between hemifacial spasm (HFS) patients and glaucoma as a function of the Botox dosage required.

Methods: A retrospective review of clinical documents and procedure records.

Results: Information of 76 consecutive patients (58 females) with HFS who received Botox treatment were reviewed. Read More

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Anterior Chamber Angle Changes in Primary Angle-closure Glaucoma Following Phacoemulsification Versus Phacotrabeculectomy: A Prospective Randomized Clinical Trial.

J Glaucoma 2022 Mar;31(3):147-155

Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Prcis: We used anterior segment optical coherence tomography to investigate anterior chamber angle in primary angle-closure glaucoma (PACG) eyes following phacoemulsification and phacotrabeculectomy. Angle widening was significantly greater after phacoemulsification up to 6 months after the surgery.

Purpose: To compare anterior chamber angle following 2 common surgeries for PACG. Read More

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Progressive ectropion uveae and secondary angle-closure glaucoma in type 1 neurofibromatosis.

Am J Ophthalmol Case Rep 2022 Mar 2;25:101345. Epub 2022 Feb 2.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Purpose: To present a case of progressive ectropion uveae and secondary angle-closure glaucoma in association with type 1 neurofibromatosis (NF-1).

Observation: An 11-year-old-Hispanic-male with a known history of NF-1 who was followed for the ocular manifestations of NF-1 developed an irregular pupil and ectropion uveae in the right eye at the age of 3 years that gradually increased in severity. The area of ectropion uveae increased in size and extended superiorly with concurrent superior synechial angle closure and intraocular pressure (IOP) elevation. Read More

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Detection of plasma complement and immune globulin in different sorts of glaucoma.

Eur J Ophthalmol 2022 Jan 28:11206721221074202. Epub 2022 Jan 28.

74573Peking University Shenzhen Hospital, 518036, PR China.

Purpose: To compare the plasma immune globulin and complement levels in different sorts of glaucoma to assess its association.

Methods: Plasma samples were collected from 226 normal controls and 236 glaucoma patients included 92 with acute primary angle-closure glaucoma (APACG), 76 with chronic primary angle-closure glaucoma (CPACG), 68 with primary open-angle glaucoma (POAG). 163 glaucoma patients with high intraocular pressure(IOP) was classified as a subgroup. Read More

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January 2022

A mysterious myopic surprise.

J Cataract Refract Surg 2022 Feb;48(2):254

Los Angeles, California.

A 73-year-old man with an ocular history of inactive age-related macular degeneration and chronic angle-closure glaucoma (CACG) in both eyes recently underwent femtosecond laser-assisted cataract surgery/phacoemulsification and intraocular lens (IOL) implantation with simultaneous Hydrus microstent (Ivantis, Inc.) implantation in the left eye. Although there was some reported subincisional iris prolapse due to intraoperative floppy iris, the case was otherwise uneventful according to the referring surgeon. Read More

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February 2022

Primary glaucomas in adults: Epidemiology and public health-A review.

Clin Exp Ophthalmol 2022 03 26;50(2):128-142. Epub 2022 Jan 26.

Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.

Glaucoma is a mixed group of optic neuropathies that lead to irreversible visual field loss and blindness if left untreated. It is estimated that 3.5% of the global population aged 40 to 80 years have any glaucoma, being the primary open-angle and the primary angle-closure glaucoma the most prevalent forms. Read More

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[Relative factors analysis of visual field defect in advanced primary glaucoma].

Zhonghua Yan Ke Za Zhi 2022 Jan;58(1):22-27

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, NHC Key Laboratory of Myopia (Fudan University), Laboratory of Myopia, Chinese Academy of Medical Science, Shanghai 200031, China.

To explore the relative factors of visual field defect in advanced primary glaucoma. A retrospective case-control study. The data of patients with primary advanced glaucoma who had the central 5 to 10 degrees of the visual field or the temporal peripheral field and were treated at Eye & ENT Hospital of Fudan University from January 2014 to December 2019 were reviewed. Read More

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January 2022

Bilateral laser peripheral iridotomy in a co-occurrence of unilateral iridocorneal endothelial syndrome and chronic angle closure glaucoma.

Eur J Ophthalmol 2021 Dec 20:11206721211067885. Epub 2021 Dec 20.

Department of Glaucoma, 161204Shri Sadguru Seva Sangh Trust, Chitrakoot Centre, Jankikund, Chitrakoot, India.

Purpose: To report a case of unilateral Iridocorneal endothelial (ICE) syndrome- Progressive iris atrophy (PIA) with an overlapping chronic angle closure glaucoma (CACG) and to highlight the effect of bilateral Laser peripheral iridotomy (LPI) in such a co-occurrence.

Case Description: A patient presented to us with bilateral gradual painless progressive diminution of vision. Both eyes (BE) had a clear cornea, shallow peripheral anterior chamber depth, grade 2 nuclear sclerosis, raised intraocular pressure and glaucomatous optic neuropathy. Read More

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December 2021

Methods to Analyze Time-to-Event Data: The Cox Regression Analysis.

Oxid Med Cell Longev 2021 30;2021:1302811. Epub 2021 Nov 30.

Division of Nephrology and Hypertension, 1st Department of Internal Medicine, AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

The Cox model is a regression technique for performing survival analyses in epidemiological and clinical research. This model estimates the hazard ratio (HR) of a given endpoint associated with a specific risk factor, which can be either a continuous variable like age and C-reactive protein level or a categorical variable like gender and diabetes mellitus. When the risk factor is a continuous variable, the Cox model provides the HR of the study endpoint associated with a predefined unit of increase in the independent variable (e. Read More

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February 2022

[Ultrasound biomicroscopic differences between fellow eyes of acute angle-closure glaucoma and chronic angle-closure glaucoma].

Zhonghua Yan Ke Za Zhi 2021 Sep;57(9):672-678

Department of Ophthalmology, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.

To compare the structural differences of the anterior segment between fellow eyes of acute angle-closure glaucoma (AACG) and the eyes of chronic angle-closure glaucoma (CACG) with milder glaucomatous damage. In this case-control study, patients with AACG (41 eyes) and CACG (46 eyes) without prior treatment in the glaucoma clinic of Peking University People's Hospital from September 2016 to October 2018 were enrolled. Ultrasound biomicroscopy was performed under dark condition. Read More

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September 2021

Glutathione S-Transferase Omega-2 and Transforming Growth Factor-1 Polymorphisms in Iranian Glaucoma Patients.

J Ophthalmol 2021 23;2021:1061650. Epub 2021 Nov 23.

Transplant Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: To investigate the association of glutathione s-transferase omega 2 (GSTO2) (142N > D) and transforming growth factor-1 (TGF-1) (869T > C) gene polymorphisms on the pathogenesis of two common types of glaucoma (including primary open-angle glaucoma (POAG) and chronic angle-closure glaucoma (CACG)) in the Iranian population.

Methods: A total of 100 glaucoma patients (60% males and 40% females with an age mean ± SD of 34.66 ± 14. Read More

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November 2021

Long-term outcomes of viscocanalostomy and phaco-viscocanalostomy in patients with narrow angle glaucoma.

Graefes Arch Clin Exp Ophthalmol 2022 Jun 24;260(6):1995-2002. Epub 2021 Nov 24.

St Pauls Eye Unit, Liverpool University Hospital, Liverpool, UK.

Purpose: To assess the outcomes of viscocanalostomy and phaco-viscocanalostomy in patients with narrow angle glaucoma at a single tertiary eye centre.

Method: All patients undergoing viscocanalostomy for narrow angle glaucoma between June 2010 and June 2017 with a minimum follow-up of 12 months were included. Data was analysed from a prospectively maintained surgical outcome database. Read More

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Successful Pars Plana Vitrectomy with Zonulo-hyaloidectomy Performed 4 Years after the Onset of Chronic Low-Grade Aqueous Misdirection.

Middle East Afr J Ophthalmol 2021 Apr-Jun;28(2):137-139. Epub 2021 Sep 25.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

In aqueous misdirection, the interval between diagnosis and surgical intervention is inversely proportional to the success of the surgery. Here, we report a successful outcome of pars plana vitrectomy (PPV) with irido-zonulo-hyaloidectomy 4 years after the onset of the disease. A 34-year-old female, known to have primary angle closure glaucoma, underwent trabeculectomy with mitomycin C in the right eye for uncontrolled intraocular pressure (IOP). Read More

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November 2021

Novel Discoveries of Anterior Segment Parameters in Fellow Eyes of Acute Primary Angle Closure and Chronic Primary Angle Closure Glaucoma.

Invest Ophthalmol Vis Sci 2021 11;62(14)

Department of Ophthalmology, Peking University People's Hospital; College of Optometry, Beijing, China.

Purpose: To investigate the biometric differences of anterior segment parameters between fellow eyes of acute primary angle closure (F-APAC) and chronic primary angle closure glaucoma (F-CPACG) to get information about differences between APAC and CPAC.

Methods: Patients with F-APAC and F-CPACG without prior treatment were enrolled from glaucoma clinics. Parameters were measured on ultrasound biomicroscopy images, including pupil diameter, lens vault (LV), anterior chamber depth, anterior chamber width, iris area, iris thickness (IT 750 and 2000), angle-opening distance (AOD 500 and 750), trabecular-iris space area (TISA 500 and 750), trabecular iris angle (TIA 500 and 750), trabecular-ciliary angle, and ciliary process area. Read More

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November 2021

Cyclophotocoagulation under Microscopy Combined with Phacoemulsification for Primary Angle-Closure Glaucoma.

J Ophthalmol 2021 21;2021:6915656. Epub 2021 Oct 21.

Department of Ophthalmology, The Affiliated Changshu Hospital of Xuzhou Medical University, Changshu, China.

The purpose of this study was to evaluate the safety and efficacy of cyclophotocoagulation under microscopy combined with phacoemulsification in patients with primary chronic angle-closure glaucoma. We retrospectively reviewed the results of cyclophotocoagulation under microscopic direct vision combined with phacoemulsification in 35 eyes (35 patients) with primary chronic angle-closure glaucoma and coexisting visually significant cataracts, treated between January 2017 and April 2020 at the glaucoma unit of the affiliated Changshu Hospital of Xuzhou Medical University. All patients were followed up for at least 12 months postoperatively. Read More

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October 2021

Corneal endothelial cell density loss following glaucoma surgery alone or in combination with cataract surgery: a systematic review protocol.

BMJ Open 2021 09 13;11(9):e050992. Epub 2021 Sep 13.

University College London Institute of Ophthalmology, London, UK

Objective: We aim to systematically assess and compare corneal endothelial cell density (ECD) loss in patients with glaucoma following glaucoma surgery and cataract surgery.

Introduction: Corneal ECD loss may occur due to intraoperative surgical trauma in glaucoma surgery or postoperatively with chronic endothelial cell trauma or irritation. Corneal oedema and decompensation after aqueous shunt glaucoma surgery has been reported but the long-term ECD loss is still unknown. Read More

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September 2021

Gonioscopy-assisted transluminal trabeculotomy for chronic angle-closure glaucoma: preliminary results.

Graefes Arch Clin Exp Ophthalmol 2022 Feb 6;260(2):545-551. Epub 2021 Sep 6.

Ophthalmology Unit, AUSL-IRCCS di Reggio Emilia, Viale Risorgimento 80, Reggio Emilia, Italy.

Purpose: To report the preliminary results of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with chronic angle-closure glaucoma (CACG).

Methods: Retrospective, single-center, case series of GATT procedures is performed on patients with CACG. The primary outcome was intraocular pressure (IOP). Read More

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February 2022

Ultrasound Biomicroscopy Might Predict the Outcome of Phacoemulsification-Visco Dissection in Medically Controlled Primary Angle-Closure Glaucoma Eye With Extensive Peripheral Anterior Synechia.

Front Med (Lausanne) 2021 19;8:705864. Epub 2021 Jul 19.

State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

The treatment procedures of primary angle-closure glaucoma (PACG) with extensive peripheral anterior synechia (PAS) is a subject of debate. This study is to investigate the clinical features of phacoemulsification (Phaco)-visco dissection in medically controlled PACG patients with PAS > 180° and evaluate the predictability of Ultrasound Biomicroscopy (UBM) parameters on postoperative intraocular pressure (IOP). 48 eyes (48 patients) with acute angle-closure glaucoma (AACG) and 30 eyes (30 patients) with chronic angle-closure glaucoma (CACG) were prospectively included. Read More

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Clinical observation of macular choroidal thickness in primary chronic angle-closure glaucoma.

Int Ophthalmol 2021 Dec 31;41(12):4217-4223. Epub 2021 Jul 31.

Department of Ophthalmology, Shijiazhuang People's Hospital, No. 365 Jianhua Street, Shijiazhuang city, Hebei Province, People's Republic of China.

Purpose: To comparatively analyze differences in macular choroidal thickness and volume in primary chronic angle-closure glaucoma (PACG) eyes.

Methods: Thirty-one PACG patients were sequentially selected for this case-control study. Thirty-one eyes with PACG were included in group A, 31 fellow eyes were included in group B, and group C included 67 normal eyes. Read More

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December 2021

Proteome Characterization of Glaucoma Aqueous Humor.

Mol Cell Proteomics 2021 30;20:100117. Epub 2021 Jun 30.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China; Proteomics Center, Chinese Academy of Medical Sciences, Beijing, China. Electronic address:

Glaucoma is the leading cause of irreversible blindness worldwide. The proteome characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 primary acute angle-closure glaucoma (PAACG), 50 primary chronic angle-closure glaucoma (PCACG), 35 neovascular glaucoma (NVG), and 33 cataract patients, were enrolled and comparison proteomic analysis was provided. Read More

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The prevalence and break down of narrow anterior chamber angle pathology presenting to a general ophthalmology clinic.

Medicine (Baltimore) 2021 Jun;100(24):e26195

East Kent Hospitals University NHS Foundations Trust, New Hayesbank NHS Eye Clinic, United Kingdom.

Abstract: To approximate the breakdown of narrow anterior chamber angle conditions, on general ophthalmology clinics, in the predominantly white population of the South East Kent region in the United Kingdom.A review was done of all patients attending a secondary care ophthalmology general clinic over a 3-year period. Patients were assessed with: slitlamp biomicroscopy with indentation gonioscopy; SD optical coherence tomography, Humphrey visual field analyzer, and high frequency ultrasound and categorized into various narrow angle conditions. Read More

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