671 results match your criteria Glaucoma Angle Closure Chronic


Bilateral angle closure glaucoma in a teenage girl - A rare presentation in Arab population - A case report.

Authors:
Sultan Alzuhairy

Int J Health Sci (Qassim) 2019 Mar-Apr;13(2):56-58

Department of Ophthalmology, College of Medicine, Qassim University, Qassim, Saudi Arabia.

Primary angle closure glaucoma (PACG) usually presents as unilateral and has acute onset. In Arab population, the proportion of open- and closed-angle glaucoma is similar. To the best of our knowledge, chronic PACG in very young age is rare. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436444PMC

Early results of micropulse transscleral cyclophotocoagulation for the treatment of glaucoma.

Eur J Ophthalmol 2019 Apr 2:1120672119839303. Epub 2019 Apr 2.

1 Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT, USA.

Purpose:: To describe our clinical experience with the efficacy and safety of micropulse transscleral cyclophotocoagulation as a treatment for glaucoma.

Methods:: In this retrospective case series, we reviewed the charts of 95 consecutive patients with various glaucoma subtypes who underwent micropulse transscleral cyclophotocoagulation. Patients were offered micropulse transscleral cyclophotocoagulation if they had perimetric glaucoma refractory to intraocular pressure-lowering topical medications and who were poor candidates for traditional filtering surgery. Read More

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http://dx.doi.org/10.1177/1120672119839303DOI Listing
April 2019
11 Reads

Influence of Anterior Biometry on Corneal Biomechanical Stiffness of Glaucomatous eyes Treated with Chronic Medication or Filtration Surgery.

J Glaucoma 2019 Mar 26. Epub 2019 Mar 26.

Imaging, Biomechanics, and Mathematical Modeling Solutions Lab, Narayana Nethralaya Foundation, Bangalore, India.

PRéCIS: Anterior chamber depth, IOP and thickness, confounded assessment of corneal biomechanical properties with non-contact applanation in glaucoma eyes. Compared to normal eyes, glaucoma eyes, which underwent long term treatment or filtration surgery, had similar properties.

Purpose: To evaluate corneal stiffness in primary angle closure (PACG) and primary open angle (POAG) glaucoma eyes sub-grouped based on type of topical medication and filtration surgery using non-contact applanation METHODS:: All eyes were retrospectively reviewed for intraocular pressure (IOP) with Corvis-ST (OCULUS Optikgerate Gmbh, Germany). Read More

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http://dx.doi.org/10.1097/IJG.0000000000001247DOI Listing

Novel inflammatory cytokines (IL-36, 37, 38) in the aqueous humor from patients with chronic primary angle closure glaucoma.

Int Immunopharmacol 2019 Mar 19;71:164-168. Epub 2019 Mar 19.

Department of Ophthalmology, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

Glaucoma eventually leads to optic nerve damage and vision loss without medical intervention. More than 50% of glaucoma caused blindness are attributed to primary angle closure glaucoma, particularly in Asians. It is reported that immune inflammation is involved in the progress of glaucoma. Read More

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http://dx.doi.org/10.1016/j.intimp.2019.03.016DOI Listing
March 2019
3 Reads

Differential Efficacy of Combined Phacoemulsification and Endocyclophotocoagulation in Open-angle Glaucoma versus Angle Closure Glaucoma.

J Glaucoma 2019 Mar 6. Epub 2019 Mar 6.

Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology, Boston, MA.

PRéCIS:: This retrospective study found that combined phacoemulsification and endocyclophotocoagulation reduced intraocular pressure to a greater degree in angle closure glaucoma versus open-angle glaucoma and was effective for all stages of glaucoma.

Purpose: Endocyclophotocoagulation (ECP, Endo Optiks, Little Silver, NJ, USA) laser treatment of the ciliary processes is believed to decrease intraocular pressure (IOP) by reducing aqueous production. Anecdotal experience in angle closure glaucoma suggests that it may also lower IOP by opening the drainage angle to promote aqueous outflow. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001225DOI Listing

The effect of phacoemulsification plus goniosynechialysis in acute and chronic angle closure patients with extensive goniosynechiae.

BMC Ophthalmol 2019 Mar 4;19(1):65. Epub 2019 Mar 4.

Department of Ophthalmology, Peking University First Hospital, 8 Xi Shi Ku Street, Xi Cheng District, Beijing, 100034, People's Republic of China.

Background: Patients with primary angle closure/glaucoma (PAC/PACG) with extensive peripheral anterior synechiae (PAS), and coexisting cataract, increasingly have been treated with phacoemulsification combined with goniosynechialysis (Phaco-GSL). Since the mechanisms of acute and chronic PAC/PACG may differ, the treatment effect of this procedure also may differ. The purpose of this study was to establish whether there was a difference in the therapeutic effect of Phaco-GSL on these two groups of patients, the results of which could provide clinical evidence for improvement in treatment protocols for patients with PAC/PACG and extensive PAS. Read More

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http://dx.doi.org/10.1186/s12886-019-1070-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399882PMC
March 2019
2 Reads

Pseudoexfoliation Syndrome and Antidepressant Drug Use

Turk J Ophthalmol 2019 Feb;49(1):1-5

Eskişehir Osmangazi University Faculty of Medicine, Department of Ophthalmology, Eskişehir, Turkey

Objectives: To investigate the relationship between pseudoexfoliation syndrome (PES) and the use of antidepressant medications.

Materials And Methods: This population-based, cross-sectional study included 2,017 of 2,356 invited subjects who were randomly selected from the Turkish Statistical Institute database (www.turksat. Read More

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http://dx.doi.org/10.4274/tjo.galenos.2018.06887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416484PMC
February 2019
2 Reads

Darkroom prone provocative testing in primary angle closure suspects and those with open angles.

Br J Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Purpose: To describe the results of darkroom prone provocative testing (DRPPT) in primary angle closure suspects (PACS) and to compare the findings to controls with open angles.

Methods: 889 subjects with PACS in the Zhongshan Angle Closure Prevention Trial (a randomised controlled trial to compare prophylactic laser iridotomy to no treatment in PACS) and 89 with open angles in the 5-year follow-up of Liwan Eye Study were placed in a darkroom face down for 15 min. Intraocular pressure (IOP) was measured immediately before and after DRPPT. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3133
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http://dx.doi.org/10.1136/bjophthalmol-2018-313362DOI Listing
February 2019
4 Reads

Indicating and predicting role of the horizontal C/D ratio in preclinical diabetic retinopathy associated with chronic angle-closure glaucoma.

Int J Ophthalmol 2019 18;12(2):268-274. Epub 2019 Feb 18.

Department of Vitreoretinopathy, Tianjin Eye Hospital, Tianjin 300020, China.

Aim: To observe morphological optic disc characteristics in patients with preclinical diabetic retinopathy (DR) associated with chronic angle-closure glaucoma (CACG).

Methods: Twenty-two cases (43 eyes) of preclinical DR associated with CACG were enrolled in group A; 24 preclinical DR cases (46 eyes) were enrolled in group B; 26 CACG cases (51 eyes) were enrolled in group C; and 49 normal controls (49 eyes) were enrolled in group D. All underwent optical coherence tomography to measure the horizontal C/D ratio (HCDR), C/D area ratio (CDaR), vertical C/D ratio (VCDR), rim area (RA), cup volume (CV), disc area (DA) and average retinal nerve fiber layer (RNFL) thickness. Read More

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http://dx.doi.org/10.18240/ijo.2019.02.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376221PMC
February 2019

Measurement of Structural Parameters of the Lamina Cribrosa in Primary Open-Angle Glaucoma and Chronic Primary Angle-Closure Glaucoma by Optical Coherence Tomography and Its Correlations with Ocular Parameters.

Ophthalmic Res 2019 Feb 15:1-10. Epub 2019 Feb 15.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China,

Purpose: To measure lamina cribrosa thickness (LCT) and anterior lamina cribrosa surface depth (ALCSD) in primary open-angle glaucoma (POAG), chronic primary angle-closure glaucoma (CPACG), and control patients using spectral-domain optical coherence tomography (SD-OCT) and examine its association with relevant ocular parameters.

Methods: In this cross-sectional study, 61 healthy volunteers (61 eyes), 65 POAG patients (65 eyes), and 55 CPACG patients (55 eyes) were recruited to obtain radial B-scans of the optic nerve head by way of enhanced depth imaging using Heidelberg SD-OCT. The obtained LCT and ALCSD were compared among the control, POAG, and CPACG groups. Read More

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http://dx.doi.org/10.1159/000496558DOI Listing
February 2019
1 Read

Surgical outcomes of phacoemulsification/goniosynechialysis with and without endocyclophotocoagulation in patients with chronic angle closure glaucoma.

Indian J Ophthalmol 2019 Mar;67(3):366-370

Department of Ophthalmology, Tulane School of Medicine, Tulane University, New Orleans, LA, USA.

Purpose: To compare surgical outcomes of patients after phacoemulsification with goniosynechialysis (phaco/GSL) versus phaco with GSL and endocyclophotocoagulation (phaco/GSL/ECP) in patients with chronic angle closure glaucoma (CACG) through 12-month follow-up.

Methods: A retrospective, nonrandomized, comparative case series was performed. Patients with CACG who underwent phaco in combination with either GSL alone (group 1) or GSL with ECP with intracameral injection of kenalog (group 2) from 2011 to 2018 were included. Read More

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http://dx.doi.org/10.4103/ijo.IJO_895_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407387PMC
March 2019
3 Reads

Comparative Clinical Study of Medically Controlled Nonsevere Chronic Primary Angle-closure Glaucoma with Coexisting Cataract Surgically Managed by Phacoemulsification as against Combined Phacotrabeculectomy.

Middle East Afr J Ophthalmol 2018 Jul-Dec;25(3-4):119-125

Research Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: Comparative clinical study of medically controlled non-severe chronic Primary Angle Closure Glaucoma (PACG) with co-existing cataract surgically managed by phacoemulsification as against combined phacotrabeculectomy.

Methods: This randomized clinical trial was conducted between December 2011 and December 2013. Patients were randomly assigned to Phacoemulsification (PE) and Phacotrabeculectomy (PT) groups for surgery. Read More

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http://dx.doi.org/10.4103/meajo.MEAJO_204_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348945PMC

One-month IOP in mitomycin C-augmented trabeculectomy can predict long-term IOP control in chronic primary angle-closure glaucoma.

Int Ophthalmol 2019 Jan 24. Epub 2019 Jan 24.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 South Xianlie Road, Guangzhou, 510060, China.

Purpose: To investigate the predictors of long-term intraocular pressure (IOP) in chronic primary angle-closure glaucoma (CPACG) treated with primary trabeculectomy.

Methods: This study systematically reviewed cases of CPACG treated with primary trabeculectomy. The scleral flaps in all cases were sutured with two stitches in situ and two releasable sutures to ensure watertight under normal IOP conditions during surgery. Read More

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http://dx.doi.org/10.1007/s10792-019-01072-1DOI Listing
January 2019
1 Read

Longitudinal Change in Peripheral Anterior Chamber Depth of Eyes with Angle Closure after Laser Iridotomy.

J Ophthalmol 2018 24;2018:9106247. Epub 2018 Dec 24.

Department of Ophthalmology, University of Yamanashi, Chuo, Yamanashi, Japan.

Purpose: To investigate longitudinal changes in peripheral anterior chamber depth (pACD) of eyes with angle closure after laser iridotomy (LI) and factors related to prognosis.

Design: Retrospective cohort study.

Methods: Eyes with primary angle closure (PAC), acute PAC, or chronic angle closure glaucoma (CACG) that underwent LI (LI group) and eyes that underwent phacoemulsification and intraocular lens insertion (PEA + IOL group) were employed. Read More

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http://dx.doi.org/10.1155/2018/9106247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323459PMC
December 2018
2 Reads

Comparison of pretreatment measurements of anterior segment parameters in eyes with acute and chronic primary angle closure.

Jpn J Ophthalmol 2019 Mar 20;63(2):151-157. Epub 2019 Jan 20.

Department of Ophthalmology, Kobe City Eye Hospital, 2-1-8, Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Purpose: To compare pretreatment anterior segment parameters between eyes with acute primary angle closure (APAC) and chronic primary angle closure (CPAC), and to identify the characteristics of eyes with APAC.

Study Design: Retrospective.

Methods: We measured pretreatment anterior chamber depth (ACD), iris convexity (IC), and pupil diameter in eyes with APAC and CPAC using anterior segment optical coherence tomography. Read More

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http://dx.doi.org/10.1007/s10384-019-00651-0DOI Listing
March 2019
1 Read

Surgical management of raised intra-ocular tension in the hostile ocular surface - recurrent tube erosion in a patient with systemic sclerosis: a case report.

BMC Ophthalmol 2018 Sep 14;18(Suppl 1):222. Epub 2018 Sep 14.

Western Eye Hospital, London, UK.

Background: The surgical management of patients with uncontrolled glaucoma and scleroderma is challenging, as the hostile ocular surface poses a challenge to surgery. A serious complication is tube erosion, with the risk of subsequent endophthalmitis. Here, we present a novel technique of harvesting autologous tissue to successfully manage recurrent tube extrusion. Read More

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http://dx.doi.org/10.1186/s12886-018-0856-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157120PMC
September 2018
3 Reads

Argon laser peripheral iridoplasty for chronic primary angle-closure and angle-closure glaucoma in caucasians.

Acta Ophthalmol 2019 Mar 21;97(2):e225-e230. Epub 2018 Sep 21.

Department of Ophthalmology, Medical Faculty Carl Gustav Carus, Technische Universität, Dresden, Germany.

Purpose: To investigate whether the peripheral thinning and shrinking of the iris as induced with Argon laser peripheral iridoplasty (ALPI) has an effect on intraocular pressure (IOP), angle structure and 3-D anterior segment (AS) morphology in Caucasians with chronic primary angle-closure (PAC) and primary angle-closure glaucoma (PACG).

Methods: Twenty-four eyes of 24 patients (age 67.7 ± 8. Read More

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http://dx.doi.org/10.1111/aos.13878DOI Listing

Profile and management outcomes of glaucoma cases at Qassim University Hospital.

Int J Health Sci (Qassim) 2018 Sep-Oct;12(5):20-24

Department of Ophthalmology, King Saud University, Riyadh, Saudi Arabia.

Objective: In view of the paucity of community-based data about glaucoma in Saudi Arabia, better planning to address visual disabilities due to glaucoma is a challenge. Providing hospital-based data from semi-urban places will complement the picture based on information of tertiary eye hospitals of capital.

Methods: This is one-armed cohort study. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124836PMC
September 2018
1 Read

Risk factors for flat anterior chamber after glaucoma filtration surgery.

Int J Ophthalmol 2018 18;11(8):1322-1329. Epub 2018 Aug 18.

Department of Ophthalmology, the Third Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China.

Aim: To investigate the incidence rate and risk factors for grade III flat anterior chamber (FAC) after glaucoma filtration surgery based on 5-year data.

Methods: Patients who underwent glaucoma filtration surgery in Daping hospital from January 2009 to December 2013 were enrolled in this retrospective study. The incidence of grade III FAC following glaucoma filtration surgery was determined. Read More

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http://dx.doi.org/10.18240/ijo.2018.08.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090123PMC
August 2018
9 Reads
0.500 Impact Factor

Acute angle closure following hemodialysis in a 34-year-old Nigerian female.

Niger J Clin Pract 2018 Jul;21(7):942-944

Department of Medicine, University College Hospital, Ibadan, Nigeria.

Studies have reported that intraocular pressure (IOP) might change markedly during hemodialysis. We report the case of a 34-year-old Nigerian female with a 3-year history of chronic kidney disease secondary to chronic glomerulonephritis who presented with acute symptomatic elevation of IOPs following hemodialysis. She had no ocular complaints immediately before undergoing hemodialysis. Read More

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http://dx.doi.org/10.4103/njcp.njcp_358_17DOI Listing
July 2018
2 Reads

Cypass Supraciliary Stent in Eye With Chronic Angle Closure and Postvitrectomy With Silicone Oil.

J Glaucoma 2018 Oct;27(10):e151-e153

El Paso Eye Surgeons, El Paso, TX.

Purpose: To report a case of successful intraocular pressure (IOP) reduction following Cypass supraciliary stent implantation in a postvitrectomized eye filled with silicone oil and chronic angle-closure glaucoma.

Materials And Methods: This is a case report.

Results: A 19-year-old female with chronic angle-closure glaucoma underwent combined cataract extraction, goniosynechiolysis and Cypass supraciliary shunt implantation. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001020DOI Listing
October 2018
3 Reads

Is combined mechanism glaucoma a distinct entity?

Graefes Arch Clin Exp Ophthalmol 2018 Oct 20;256(10):1961-1969. Epub 2018 Jun 20.

Glaucoma Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute Of Medical Sciences, Room no 494, 4th floor, New Delhi, 110029, India.

Purpose: Primary adult glaucomas that have an occludable angle with peripheral anterior synechiae which are too few to account for the chronically raised IOP, or the glaucomatous optic neuropathy, do not fit the definition of either POAG or PACG and can be considered as combined mechanism glaucoma (CMG). We aimed to compare the clinical features and anatomical parameters of combined mechanism glaucoma with age, sex, and refraction-matched POAG and chronic PACG eyes.

Methods: Consecutive adult patients with definitive optic nerve head and perimetric changes of glaucoma were screened at a tertiary care center. Read More

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http://dx.doi.org/10.1007/s00417-018-4050-5DOI Listing
October 2018
6 Reads
1.910 Impact Factor

[Blinding spontaneous suprachoroidal haemorrhage in anticoagulant taking wet-AMD patients].

Orv Hetil 2018 Jun;159(24):985-990

Szemészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Mária u. 39., 1085.

We present cases of blinding spontaneous suprachoroidal haemorrhage in anticoagulant taking wet-AMD patients. A retrospective study has been performed to present the clinical course, management and final outcome of spontaneous suprachoroidal haemorrhage in 7 eyes of six age-related macular degeneration patients seen in our clinic from January 2016 to April 2017. All patients were on chronic oral anticoagulant therapy because of cardiovascular disorder. Read More

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http://dx.doi.org/10.1556/650.2018.30966DOI Listing
June 2018
3 Reads

Systemic medication usage in glaucoma patients.

Can J Ophthalmol 2018 06 1;53(3):242-245. Epub 2018 Feb 1.

?>Department of Ophthalmology, Jewish General Hospital, McGill University, Montreal, Que. Electronic address:

Objective: To study the prevalence of the systemic use of some common classes of medications by glaucoma patients and their relationship to the prevalence and severity of chronic open-angle glaucoma (COAG) and primary-angle closure glaucoma (PACG).

Design: Observational prospective single-centre cross-sectional study.

Methods: Glaucoma patients or their pharmacist provided an updated list of all systemic medications that they presently use. Read More

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http://dx.doi.org/10.1016/j.jcjo.2017.10.029DOI Listing
June 2018
4 Reads

Factors Associated with Outcomes of Combined Phacoemulsification and Ahmed Glaucoma Valve Implantation.

Korean J Ophthalmol 2018 06 15;32(3):211-220. Epub 2018 May 15.

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: To evaluate outcomes and factors associated with surgical failure in patients who underwent combined phacoemulsification and Ahmed glaucoma valve (AGV) implantation.

Methods: This retrospective and longitudinal study enrolled 40 eyes (38 patients) that underwent combined phacoemulsification and AGV implantation. Visual acuity, intraocular pressure (IOP), and number of antiglaucoma medications were evaluated preoperatively and postoperatively. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3341/kjo.2017.01
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http://dx.doi.org/10.3341/kjo.2017.0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990640PMC
June 2018
1 Read

In Reply: Long-term Evaluation of Specular Microscopic Changes Following Nd: YAG Iridotomy in Chronic Primary Angle-closure Glaucoma Eyes.

J Glaucoma 2018 Aug;27(8):e143-e144

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1097/IJG.0000000000000975DOI Listing
August 2018
9 Reads
2.430 Impact Factor

Visual Subfield Progression in Glaucoma Subtypes.

J Ophthalmol 2018 21;2018:7864219. Epub 2018 Mar 21.

Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Purpose: To investigate visual field progression pattern and factors associated with progression in patients with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and chronic angle-closure glaucoma (CACG).

Methods: The raw data of the 30-2 Humphrey Field Analyzer from glaucoma patients with definite visual field progression were processed with pointwise linear regression (PLR) analysis. The rate of change of retinal threshold sensitivity in the ten glaucoma hemifield test (GHT) zones, the upper and the lower hemifields, and the whole field was evaluated and was correlated with patients' basic demographic data. Read More

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https://www.hindawi.com/journals/joph/2018/7864219/
Publisher Site
http://dx.doi.org/10.1155/2018/7864219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883978PMC
March 2018
4 Reads

Secondary Angle Closure due to Crystalline Lens Dislocation in a Patient with Atopic Dermatitis and Chronic Eye Rubbing.

Case Rep Ophthalmol 2018 Jan-Apr;9(1):197-201. Epub 2018 Mar 22.

Department of Ophthalmology, William H. Havener Eye Institute, The Ohio State University Medical Center, Columbus, Ohio, USA.

Purpose: To report an unusual case of ectopia lentis and angle closure in a patient with chronic eye rubbing.

Methods: A 57-year-old male with a history of poorly controlled atopic dermatitis presented with right eye pain, decreased vision, and an intraocular pressure (IOP) of 55 mm Hg. He had no past history of ocular disease and no reported history of trauma. Read More

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https://www.karger.com/Article/FullText/486752
Publisher Site
http://dx.doi.org/10.1159/000486752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903097PMC
March 2018
4 Reads

Refractive outcomes of phacoemulsification cataract surgery in glaucoma patients.

J Cataract Refract Surg 2018 Mar 28;44(3):348-354. Epub 2018 Mar 28.

From the Department of Ophthalmology (Manoharan, Patnaik, Bonnell, SooHoo, Pantcheva, Kahook, Wagner, Lynch, Seibold), University of Colorado School of Medicine and the Department of Biostatistics and Informatics (Wagner), University of Colorado School of Public Health, Aurora, Colorado, USA. Electronic address:

Purpose: To evaluate refractive outcomes after phacoemulsification cataract surgery in patients with glaucoma.

Setting: University of Colorado Health Eye Center, Aurora, Colorado, USA.

Design: Retrospective case series. Read More

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http://dx.doi.org/10.1016/j.jcrs.2017.12.024DOI Listing
March 2018
5 Reads

Combined Phacoemulsification and Goniosynechialysis under an Endoscope for Chronic Primary Angle-Closure Glaucoma.

J Ophthalmol 2018 8;2018:8160184. Epub 2018 Feb 8.

Department of Mechanical Engineering, University of Hong Kong, Pokfulam, Hong Kong.

Purpose: To investigate the clinical efficacy and safety of combined phacoemulsification with goniosynechialysis (GSL) under an ophthalmic endoscope for chronic primary angle-closure glaucoma and coexisting cataract.

Methods: This is a retrospective study. The intraocular pressure (IOP), best-corrected visual acuity (BCVA), and number of glaucoma medications at baseline and each postoperative follow-up visit were recorded. Read More

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http://dx.doi.org/10.1155/2018/8160184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822755PMC
February 2018
5 Reads

Macular Choroidal Small-Vessel Layer, Sattler's Layer and Haller's Layer Thicknesses: The Beijing Eye Study.

Sci Rep 2018 Mar 13;8(1):4411. Epub 2018 Mar 13.

Beijing Institute of Ophthalmology and Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

To study macular choroidal layer thickness, 3187 study participants from the population-based Beijing Eye Study underwent spectral-domain optical coherence tomography with enhanced depth imaging for thickness measurements of the macular small-vessel layer, including the choriocapillaris, medium-sized choroidal vessel layer (Sattler's layer) and large choroidal vessel layer (Haller's layer). In multivariate analysis, greater thickness of all three choroidal layers was associated (all P < 0.05) with higher prevalence of age-related macular degeneration (AMD) (except for geographic atrophy), while it was not significantly (all P > 0. Read More

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http://dx.doi.org/10.1038/s41598-018-22745-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849687PMC
March 2018
5 Reads

Retinal pigment epithelium changes in Kartagener syndrome.

Am J Ophthalmol Case Rep 2018 Jun 8;10:119-121. Epub 2018 Feb 8.

Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 900 NW 17th Avenue, Miami, FL, 33136, USA.

Purpose: We present the first case in the literature of a patient with Kartagener syndrome and ocular findings of nonexudative age-related macular degeneration.

Observations: A 55-year-old woman with Kartagener syndrome and chronic angle closure glaucoma presented for evaluation of the retina. Optos ultra-widefield imaging of the fundus showed glaucomatous cupping, drusen, and retinal pigment epithelium changes within the macular region. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834646PMC
June 2018
21 Reads

Ocular Biometry in Primary Angle-Closure Glaucoma Associated with Retinitis Pigmentosa.

J Ophthalmol 2017 31;2017:9164846. Epub 2017 Dec 31.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Background: Retinitis pigmentosa (RP) comprises a group of inherited disorders in which patients typically lose night vision in adolescence and then lose peripheral vision in young adulthood before eventually losing central vision later in life. A retrospective case-control study was performed to evaluate differences in ocular biometric parameters in primary angle-closure glaucoma (PACG) patients with and without concomitant RP to determine whether a relationship exists between PACG and RP.

Methods: We used ultrasound biomicroscopy (UBM) to measure anterior chamber depth (ACD). Read More

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http://dx.doi.org/10.1155/2017/9164846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804412PMC
December 2017
6 Reads

Differences between fellow eyes of acute and chronic primary angle closure (glaucoma): An ultrasound biomicroscopy quantitative study.

PLoS One 2018 15;13(2):e0193006. Epub 2018 Feb 15.

Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

Purpose: To compare various biometric parameters between fellow eyes of acute primary angle closure (glaucoma) [APAC(G)] and fellow eyes of chronic primary angle closure (glaucoma) [CPAC(G)].

Methods: Ultrasound biomicroscopy examinations were performed on 47 patients with unilateral APAC(G) and 41 patients with asymmetric CPAC(G) before laser peripheral iridotomy and pilocarpine treatment. Anterior chamber depth and width (ACD and ACW), lens vault (LV), iris curvature (IC), iris root distance (IRD), trabecular-ciliary process distance (TCPD), iris-ciliary process distance (ICPD), trabecular-ciliary angle (TCA), and other biometric parameters were compared between fellow eyes of APAC(G) and fellow eyes of CAPC(G). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193006PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814014PMC
April 2018
8 Reads

Acute hypotony maculopathy following the initiation of a topical aqueous suppressant in a patient with a history of panuveitis without prior filtering surgery.

Am J Ophthalmol Case Rep 2017 Sep 22;7:95-98. Epub 2017 Jun 22.

Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, 1450 San Pablo Street, Los Angeles, CA 90033, United States.

Purpose: To report a case of profound hypotony maculopathy as a complication of single-agent glaucoma therapy in a patient with a history of panuveitis without previous filtering surgery.

Observations: A 70-year old Hispanic male with a history of resolved bilateral panuveitis, chronic angle closure glaucoma, and pars plana vitrectomy was started on topical timolol 0.5% daily in the left eye for mildly elevated intraocular pressure (15 mmHg). Read More

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http://dx.doi.org/10.1016/j.ajoc.2017.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722180PMC
September 2017
11 Reads

Retrospective review on the outcome and safety of transscleral diode laser cyclophotocoagulation in refractory glaucoma in Chinese patients.

Int Ophthalmol 2019 Jan 11;39(1):41-46. Epub 2017 Dec 11.

Department of Ophthalmology, United Christian Hospital, Kwun Tong, Hong Kong.

Purpose: Transscleral cyclodiode laser cyclophotocoagulation (TSCP) is often reserved for treatment of refractory glaucoma. This retrospective study investigates the safety and efficacy of TSCP among the Chinese population.

Methods: A retrospective review was performed on electronic patient records of all patients receiving TSCP between years 2009 to year 2016. Read More

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http://dx.doi.org/10.1007/s10792-017-0782-1DOI Listing
January 2019
4 Reads

Hypertonic Saline Injection Model of Experimental Glaucoma in Rats.

Methods Mol Biol 2018 ;1695:11-21

Casey Eye Institute, Oregon Health and Science University, 3375 S.W. Terwilliger Blvd, Portland, OR, 97239, USA.

A reliable method of creating chronic elevation of intraocular pressure (IOP) in rodents is an important tool in reproducing and studying the mechanisms of optic nerve injury that occur in glaucoma. In addition, such a model could provide a valuable method for testing potential neuroprotective treatments. This paper outlines the basic methods for producing obstruction of aqueous humor outflow and IOP elevation by injecting hypertonic saline (a sclerosant) into the aqueous outflow pathway. Read More

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http://dx.doi.org/10.1007/978-1-4939-7407-8_2DOI Listing
July 2018
15 Reads

Biometric Differences between Unilateral Chronic Primary Angle Closure Glaucoma and Fellow Non-Glaucomatous Eyes.

Semin Ophthalmol 2018 29;33(5):595-601. Epub 2017 Nov 29.

a Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology , Sun Yat-Sen University , Guangzhou , China.

Purpose: To compare biometric differences between eyes with unilateral chronic primary angle-closure glaucoma (PACG) and fellow non-glaucomatous eyes in the same patient.

Methods: Clinical data and imaging records of 17 patients with unilateral PACG were retrospectively reviewed. The fellow eyes with primary angle-closure (PAC) or primary angle-closure suspected (PACS) were grouped in Group 1. Read More

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http://dx.doi.org/10.1080/08820538.2017.1375121DOI Listing
July 2018
13 Reads

Acute angle closure glaucoma - A potential blind spot in critical care.

J Intensive Care Soc 2017 Aug 3;18(3):244-246. Epub 2017 Apr 3.

Milton Keynes University Hospital, NHS Foundation Trust, Milton Keynes, UK.

We report a case of a 69-year-old gentleman who developed an acutely painful eye with loss of visual acuity whilst on the critical care unit. He was admitted three days previously with an infective exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation. In addition, he received intravenous antibiotics, steroids, nebulised bronchodilators and intravenous aminophylline, together with noradrenaline for blood pressure support. Read More

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http://dx.doi.org/10.1177/1751143717701946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665139PMC
August 2017
2 Reads

Ocular Features of Cerebro-Costo-Mandibular Syndrome.

J Glaucoma 2018 Jan;27(1):e21-e23

Royal Surrey County Hospital.

Cerebro-costo-mandibular syndrome (CCMS) is a rare hereditary disorder characterized by micrognathia, posterior rib gaps, and secondary developmental delay. Patients often require ventilation and feeding support throughout life. We describe the first reported ophthalmic findings of CCMS and propose that defects in choroidal permeability lead to chronic macular edema and refractory aqueous misdirection syndrome. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000815DOI Listing
January 2018
5 Reads

Acute and chronic fluid misdirection syndrome: pathophysiology and treatment.

Graefes Arch Clin Exp Ophthalmol 2018 Jan 6;256(1):135-154. Epub 2017 Nov 6.

Department of Ophthalmology, Medical University of Gdańsk, Gdańsk, Poland.

Purpose: To summarize our current understanding of the specific pathogenic mechanisms of the fluid misdirection syndrome and possible treatment methods.

Methods: We used the PubMed web platform to find relevant studies using the following keywords: infusion misdirection syndrome, aqueous misdirection syndrome, ciliary block, ciliovitreal block, capsular block, intraoperative fluid misdirection, subcapsular fluid entrapment, acute intraoperative rock-hard eye syndrome, positive vitreous pressure glaucoma, and malignant glaucoma. Other publications were also considered as a potential source of information when referenced in relevant articles. Read More

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http://dx.doi.org/10.1007/s00417-017-3837-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748435PMC
January 2018
3 Reads

Ocular pulse amplitude in different types of glaucoma using dynamic contour tonometry: Diagnosis and follow-up of glaucoma.

Exp Ther Med 2017 Nov 30;14(5):4148-4152. Epub 2017 Aug 30.

Department of Ophthalmology, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, Jiangsu 214000, P.R. China.

The aim of the present study was to compare the ocular pulse amplitude (OPA) in patients with different types of glaucoma using dynamic contour tonometry (DCT), to evaluate ocular and systemic factors associated with the OPA and to verify whether OPA measured by DCT is an independent predictor for glaucoma diagnosis. A total of 217 eyes of 217 participants in the following five groups were included in this cross-sectional study: Chronic angle closure glaucoma (CACG), primary open angle glaucoma, normal tension glaucoma (NTG), suspected open angle glaucoma (SOAG) and normal control (NC). The following tests were simultaneously performed during a single visit: Intra-ocular pressure (IOP), OPA, cup-to-disk (C/D) ratio, mean damage (MD) and loss variance (LV). Read More

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http://www.spandidos-publications.com/10.3892/etm.2017.5074
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http://dx.doi.org/10.3892/etm.2017.5074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658696PMC
November 2017
4 Reads

Chronic and Intermittent Angle Closure Caused by In-The-Bag Capsular Tension Ring and Intraocular Lens Dislocation in Patients With Pseudoexfoliation Syndrome.

J Glaucoma 2017 Nov;26(11):1051-1055

*Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne †Department of Ophthalmology, Cantonal Hospital of Winterthur, Winterthur, Switzerland.

Purpose: A subluxation or dislocation of the intraocular lens (IOL) is a well-known complication after cataract surgery in patients with pseudoexfoliation syndrome (PEX). Capsular tension rings (CTR) are frequently used to prevent postoperative complications caused by zonular weakness. Here we present a series of 7 cases, 2 with intermittent and 5 with acute angle closure caused by a combination of PEX-associated zonular weakness and a resulting unstable capsular bag-CTR-IOL complex. Read More

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http://dx.doi.org/10.1097/IJG.0000000000000780DOI Listing
November 2017
8 Reads

Long-term scanning laser ophthalmoscopy and perimetry in different severities of primary open and chronic angle closure glaucoma eyes.

Indian J Ophthalmol 2017 Oct;65(10):963-968

Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To determine rate of change over time on scanning laser ophthalmoscopy, HRT, compared to perimetry, and to determine incidence, parametric changes, and risk factors for progression in primary open angle glaucoma (POAG) and chronic primary angle closure angle glaucoma (CPACG) eyes.

Methods: Prospective clinical study of 116 POAG eyes and 129 CPACG eyes of different severities of glaucoma. Standard automated perimetry and optic nerve head topography were studied at baseline and thereafter every 6 months. Read More

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http://dx.doi.org/10.4103/0301-4738.216734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678332PMC
October 2017
20 Reads

A Family of Early English Oculists (1600-1751), With a Reappraisal of John Thomas Woolhouse (1664-1733/1734).

Ophthalmol Eye Dis 2017 29;9:1179172117732042. Epub 2017 Sep 29.

Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Naples, FL, USA.

Introduction: John Thomas Woolhouse (1666-1733/1734), who practiced in Paris, was part of a family with 5 generations of English oculists. Some historians have derided him as a "charlatan" and have criticized him for adhering to the old notion that a cataract was a membrane anterior to the lens.

Methods: We reviewed treatises and digital records related to Woolhouse and his family and the handwritten notes of his 1721 lecture series at the Royal Society of Medicine. Read More

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http://dx.doi.org/10.1177/1179172117732042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624362PMC
September 2017
2 Reads

Multiplex Cytokine Analysis of Aqueous Humor from the Patients with Chronic Primary Angle Closure Glaucoma.

Curr Eye Res 2017 12 22;42(12):1608-1613. Epub 2017 Sep 22.

a Department of Genetics , Aravind Medical Research Foundation , Madurai , Tamil Nadu , India.

Purpose: To compare the levels of cytokines and growth factor in aqueous humor of the patients with chronic primary angle closure glaucoma (PACG) and cataract.

Methods: Aqueous humor samples were collected from 19 chronic PACG patients and compared with 14 nonglaucomatous controls presenting for cataract surgery. The levels of 27 cytokines and growth factors were measured in the aqueous samples using multiplex bead immunoassay and compared across groups. Read More

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http://dx.doi.org/10.1080/02713683.2017.1362003DOI Listing
December 2017
33 Reads
1.663 Impact Factor

Glaucoma Surgery in Scleromalacia: Using Endoscopic Cyclophotocoagulation where Conventional Filtration Surgery or Angle Procedures are contraindicated.

J Curr Glaucoma Pract 2017 May-Aug;11(2):73-75. Epub 2017 Aug 5.

Consultant, Department of Ophthalmology, St Thomas' Hospital, London United Kingdom.

Aim: To describe the surgical management of glaucoma in a patient with severe scleromalacia, and secondary angle closure.

Introduction: The management of glaucoma with coexisting scleromalacia plus secondary angle closure is challenging as most commonly performed incisional glaucoma surgery as well as minimally invasive glaucoma surgery (MIGS), which targets the drainage angle are all contraindicated.

Case Report: Medically refractory glaucoma in a 60-year-old male with a 30-year history of granulomatosis with polyangiitis resulting in extensive severe scleromalacia, cicatricial lower lid retraction with significant conjunctival exposure, and widespread synechial angle closure from chronic anterior uveitis was managed with combined phacoemulsification cataract surgery, and endoscopic cyclophotocoagulation (ECP). Read More

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http://dx.doi.org/10.5005/jp-journals-10028-1227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577124PMC
August 2017
34 Reads

Optic Nerve Head Characteristics in Chronic Angle Closure Glaucoma Detected by Swept-Source OCT.

Curr Eye Res 2017 11 18;42(11):1450-1457. Epub 2017 Sep 18.

b Department of Ophthalmology , Massachusetts Eye and Ear, Harvard Medical School , Boston , MA , USA.

Purpose: To compare structural features in prelaminar and laminar tissues of the optic nerve head (ONH) in chronic angle closure glaucoma (CACG), primary open angle glaucoma (POAG), and control subjects.

Materials And Methods: ONH imaging was performed using swept-source optical coherence tomography (SS-OCT) for measurements of minimum rim width at Bruch's membrane opening (BMO-MRW), horizontal, and vertical lamina cribrosa depth (LCD). Prelaminar defects, categorized as hole and wedge, and lamina cribrosa (LC) defects were identified. Read More

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http://dx.doi.org/10.1080/02713683.2017.1341535DOI Listing
November 2017
7 Reads