1,515 results match your criteria Glaucoma Angle Closure Acute


Is there an association of socioeconomic deprivation with acute primary angle closure?

Eye (Lond) 2021 Jun 11. Epub 2021 Jun 11.

Princess Alexandra Eye Pavilion, Edinburgh, UK.

Background: Socioeconomic deprivation is known to increase the risk of late presentation of many diseases. This is the largest study in United Kingdom investigating the relationship between socioeconomic deprivation and acute primary angle closure (APAC).

Methods: A retrospective review of case notes was conducted of 718 consecutive patients who underwent laser peripheral iridotomy (LPI) in Edinburgh (Princess Alexandra Eye Pavilion) and Fife (Queen Margaret Hospital) between 2015 and 2019. Read More

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A system review and meta-analysis of the treatment of acute angle-closure glaucoma under optical coherence tomography.

Ann Palliat Med 2021 May;10(5):5659-5670

Department of Ophthalmology, Affiliated Hospital of Hebei University, Baoding, China.

Background: A meta-analysis was conducted to investigate the value of treatment-related indicators of acute angle-closure glaucoma (AACG) based on optical coherence tomography (OCT) to evaluate the curative effect.

Methods: Articles on the treatment of AACG in clinical research of OCT published from January 2010 to June 2020 were retrieved from the PubMed, Web of Science, and Spring databases. RevMan 5. Read More

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Topiramate-induced Acute Transient Myopia and Angle Narrowing.

J Coll Physicians Surg Pak 2021 Jun;30(6):728-731

Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.

Sulphamate drugs, widely prescribed for various systemic conditions, are reported to have rare ocular adverse-effects, usually within weeks of initiation of treatment. Medical and drug history in such cases are of pivotal importance in reaching a proper diagnosis. This study reports three cases, which developed topiramate-induced ocular side effects. Read More

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Vitreociliary Block in a Patient With Uveitis and Previous Laser Posterior Capsulotomy.

Cureus 2021 May 1;13(5):e14786. Epub 2021 May 1.

Ophthalmology, 12 de Octubre Hospital, Complutense University, Madrid, ESP.

Purpose: To report a case of vitreociliary block (VCB) six months after a laser posterior capsulotomy (LPC).

Case Report: A 25-year-old man with uveitis, retinal vasoproliferative tumor, cataract, and acute angle-closure glaucoma due to pupillary seclusion, which required laser iridotomies, implantation of an Ahmed valve, phacoemulsification, and LPC. Six months after capsulotomy, he presented a generalized flattening of the anterior chamber (AC) and ocular hypertension, with patent iridotomies. Read More

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Topiramate-induced angle closure glaucoma: Two unique case reports.

Saudi J Ophthalmol 2020 Jul-Sep;34(3):202-204. Epub 2021 Feb 27.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

The aim of this study is to report the side effects of oral topiramate in two young patients presented with bilateral ocular blurring and discomfort, causing unique development of secondary acute angle closure (AAC) after discontinuation of oral topiramate. Both patients, with a history of seizure and migraine, respectively, were taking oral topiramate to control their mentioned diseases. Both had secondary AAC and high intraocular pressure, after discontinuing topiramate. Read More

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February 2021

Secondary DMEK following failed primary DMEK.

Int Ophthalmol 2021 Jun 2. Epub 2021 Jun 2.

Department of Ophthalmology, Philipps University, 35043, Marburg, Germany.

Purpose: To report the outcomes of secondary Descemet Membrane Endothelial Keratoplasty (DMEK) performed for failed primary DMEK.

Methods: The medical records of all patients undergoing secondary DMEK due to failure of primary DMEK were reviewed. Reasons for failure were sought and best-corrected visual acuity (BCVA), endothelial cell density (ECD) and complications of secondary DMEK were evaluated. Read More

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Comparing the Safety and Efficacy of Phacogoniosynechialysis With Phacotrabeculectomy in the Management of Refractory Acute Primary Closure Angle Glaucoma With Cataract: A Multicenter Randomized Trial.

J Glaucoma 2021 May 11. Epub 2021 May 11.

Vietnam National Eye Hospital Military Hospital 103, Military Medical University Ha Dong Eye Hospital Hanoi Medical University, Hanoi, Vietnam Singapore National Eye Centre, Singapore Eye Research Institute, National University of Singapore, Singapore, Singapore.

Prcis: Combined phacoemulsification-goniosynechialysis (phaco-GSL) and unaugmented phacotrabeculectomy were both found to be effective in treating eyes with significant cataract and medically unresponsive acute primary angle closure glaucoma (PACG). Phaco-GSL seemed to be safer, with fewer surgical complications, and achieved better visual acuity than phacotrabeculectomy.

Objectives: To compare the results of combined phaco-GSL with unaugmented phacotrabeculectomy in the management of eyes with medically unresponsive acute PACG and cataract. Read More

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Vitreous Decompression Combined with Phacoemulsification for Medically Unresponsive Acute Angle Closure.

J Ophthalmol 2021 22;2021:5528281. Epub 2021 Apr 22.

Department of Ophthalmology, The Affiliated Changshu Hospital of Xuzhou Medical University, Changshu, China.

The management of acute angle closure combined with an extremely shallow anterior chamber and cataract remains complex. This study evaluated a technique of vitreous needle aspiration combined with phacoemulsification for the treatment of acute angle closure with continuous high intraocular pressure (IOP). We retrospectively reviewed the results of vitreous needle aspiration combined with phacoemulsification in 17 eyes (17 patients) with acute angle closure with continuous high IOP and coexisting visually significant cataracts between September 2018 and April 2020 at the glaucoma unit of the affiliated Changshu Hospital of Xuzhou Medical University. Read More

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Lessons From Management: Perioperative Phacoemulsification Planning Following Resolution of Acute Angle Closure.

Cureus 2021 Apr 6;13(4):e14331. Epub 2021 Apr 6.

Faculty of Medicine, University of New South Wales, Sydney, AUS.

Patients with loose zonular apparatus after acute angle closure may require phacoemulsification cataract surgery. The authors' experience from management of such patients provides excellent instruction on the surgical intervention for their cataracts. This is because patients who have recovered from acute angle closure glaucoma may not have evident zonular laxity preoperatively, as the iris may be taut secondary to the effects of associated ischaemia. Read More

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Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography.

Int Ophthalmol 2021 May 5. Epub 2021 May 5.

Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.

Purpose: To investigate the changes and evaluate the diagnosis value of circumpapillary vessel density (VD) in cases of acute primary angle closure (APAC).

Design: Case-control study.

Methods: APAC patients with a history of unilateral acute attack were enrolled. Read More

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Polypharmacy-associated potential contraindications of drug prescriptions in patients with primary angle closure disease in a real-world setting.

J Pharm Health Care Sci 2021 May 3;7(1):17. Epub 2021 May 3.

Present Address: Department of Pharmacy, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi, Chuo-ku, Kobe, 650-0047, Japan.

Background: Primary angle closure disease (PACD) is a type of glaucoma in which the intraocular pressure (IOP) is increased because of the blockage of the anterior chamber angle. Medications contraindicated for patients with PACD, such as anticholinergics, cause mydriasis, and can elevate IOP. However, anticholinergics are currently contraindicated only for primary angle closure glaucoma (PACG) in Japanese package inserts. Read More

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Bilateral Acute Angle Closure Glaucoma after Prone Position Ventilation for COVID 19 Pneumonia.

J Glaucoma 2021 Apr 28. Epub 2021 Apr 28.

Department of Ophthalmology, Deenanath Mangeshkar Hospital and Research Centre, Erandawne, Near Mhatre Bridge, Pune 411004, India.

We report a case of bilateral acute angle closure glaucoma developing after prone position ventilation for severe COVID 19 pneumonia. A 53-year-old diabetic and hypertensive male developed blurred vision and ocular discomfort in both eyes after prone position ventilation for severe COVID 19 pneumonia. At initial examination he was noted to have diffuse corneal edema with shallow anterior chambers and mid dilated non reacting pupils. Read More

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Anterior vitrectomy, phacoemulsification cataract extraction and irido-zonulo-hyaloid-vitrectomy in protracted acute angle closure crisis.

Int Ophthalmol 2021 Apr 27. Epub 2021 Apr 27.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China.

Purpose: To describe a modified surgical approach with anterior vitrectomy, phacoemulsification (phaco) cataract extraction and irido-zonulo-hyaloid-vitrectomy (IZHV) in protracted acute angle closure crisis (AACC).

Patients And Methods: Non-comparative, retrospective case series including 21 eyes in 19 consecutive cases of protracted AACC, which persists for at least 7 days despite maximal medical and laser therapies, were included in this study. All patients underwent a modified surgical procedure with anterior vitrectomy, phaco cataract extraction, IOL implantation, goniosynechialysis (GSL) and IZHV, using modest phaco dynamic parameters with intraocular pressure (IOP) set at 30 mmHg through the procedure using Centurion® Vision System equipped with active fluidics while the anterior vitrectomy was set at 4000 or 5000 rpm. Read More

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Acute bilateral angle closure induced by monoclonal antibody (Daratumumab) infusion.

Am J Ophthalmol Case Rep 2021 Jun 26;22:101079. Epub 2021 Mar 26.

Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.

Purpose: To report a case of daratumumab-induced bilateral angle closure glaucoma and myopia that showed no recurrence after repeated drug administration with prophylactic cycloplegia.

Observations: A 63-year-old man with relapsing multiple myeloma presented with acute bilateral eye pain and blurred vision 14 hours after first daratumumab infusion. Eye examination revealed raised intraocular pressure and shallow anterior chamber. Read More

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Aqueous misdirection syndrome following ab interno gelatin stent can be managed successfully with anterior vitrectomy approach.

Eur J Ophthalmol 2021 Apr;31(1_suppl):16-19

Health Education KSS, East Surrey Hospital, Redhill, UK.

Introduction: Minimally invasive glaucoma surgery (MIGS) is a relatively new surgical technique available to glaucoma surgeons. The ab interno gelatin XEN stent (XEN®45, Allergan Inc., CA, USA) drains aqueous into the subconjunctival space and is theoretically less invasive than trabeculectomy and therefore carries less risk. Read More

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A Rare Case of Acute Bilateral Endothelial Decompensation after Prophylactic Nd:YAG Laser Iridotomy Requiring Endothelial Keratoplasty.

J Curr Glaucoma Pract 2020 Sep-Dec;14(3):109-111

Department of Ophthalmology, Shaare Zedek Medical Center, Affiliated to the Hebrew University, Jerusalem, Israel.

Aim: To describe a case of acute bilateral endothelial decompensation following prophylactic Nd:YAG laser iridotomy (LI) for occludable angles.

Background: Although regarded safe, LI can occasionally be a source of various ocular complications, including corneal endothelial damage. In the herein case, we describe the first case of acute bilateral endothelial decompensation after Nd:YAG LI. Read More

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Acute Bilateral Angle-Closure Glaucoma Related to Intranasal Cocaine Abuse.

Klin Monbl Augenheilkd 2021 Apr 14. Epub 2021 Apr 14.

Ophthalmology, Alicante General University Hospital, Alicante, Spain.

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The kebab technique uses a bipolar pencil to retrieve a dropped nucleus of the lens via a small incision.

Sci Rep 2021 Apr 12;11(1):7897. Epub 2021 Apr 12.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.

We developed a new method to retrieve a dropped nucleus of the lens via a small incision using bipolar pencils, the kebab technique, to solve the lack of small-gauge fragmatomes, and the expense and toxicity of perfluorocarbon liquids (PFCL). A total of 8 eyes in 6 patients underwent this technique and were reviewed. After vitrectomy, the dropped nucleus of the lens was lifted from the retina by adhesion with a bipolar pencil, and phacoemulsification was performed while rotating the lens. Read More

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Report of a Cluster of Cases of Toxic Anterior-segment Syndrome After Implantation of a Specific Intraocular Lens Model.

Am J Ophthalmol 2021 Apr 5;228:1-7. Epub 2021 Apr 5.

From the Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo.

Purpose: To report a cluster of cases of toxic anterior-segment syndrome (TASS) in eyes implanted with a specific foldable acrylic intraocular lens (IOL) model.

Design: Retrospective case series.

Methods: The medical records were reviewed for 7 eyes of 4 patients diagnosed with TASS after cataract surgery at Shimane University and Matsue Red Cross Hospital between July and November 2020. Read More

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Ten-Year Clinical Outcomes of Acute Primary Angle Closure Randomized to Receive Early Phacoemulsification Versus Laser Peripheral Iridotomy.

J Glaucoma 2021 Apr;30(4):332-339

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong.

Purpose: To compare the 10-year clinical outcomes of eyes with acute primary angle closure (APAC) randomized to receive either early phacoemulsification or laser peripheral iridotomy (LPI).

Methods: Sixty-two APAC patients, who underwent either early phacoemulsification (phaco group) or laser peripheral iridotomy (LPI group) in a previous randomized controlled trial, were invited for assessment 10 years after the interventions. The results of the 2 groups were compared. Read More

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Lens extraction for chronic angle-closure glaucoma.

Cochrane Database Syst Rev 2021 03 24;3:CD005555. Epub 2021 Mar 24.

Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.

Background: Primary angle-closure glaucoma (PACG) is characterized by a rise in intraocular pressure (IOP) secondary to aqueous outflow obstruction, with relative pupillary block being the most common underlying mechanism. There is increasing evidence that lens extraction may relieve pupillary block and thereby improve IOP control. As such, comparing the effectiveness of lens extraction against other commonly used treatment modalities can help inform the decision-making process. Read More

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Laser peripheral iridoplasty for chronic angle closure.

Cochrane Database Syst Rev 2021 03 23;3:CD006746. Epub 2021 Mar 23.

Centre for Public Health, Queen's University Belfast, Belfast, UK.

Background: In at least a third of primary angle closure cases, appositional angle closure persists after laser peripheral iridotomy, and further intervention may be considered. Laser peripheral iridoplasty (LPIp) can be used in treating chronic angle closure when angle closure persists after laser peripheral iridotomy. Previous reviews have found insufficient data to determine its clinical effectiveness, compared to other interventions. Read More

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Rate of central corneal thickness changes in primary angle closure eyes: long-term follow-up results.

BMC Ophthalmol 2021 Mar 22;21(1):145. Epub 2021 Mar 22.

Department of Ophthalmology, Hanyang University College of Medicine, 222-1, Wangsimni-ro Seongdong-gu, Seoul, 04763, South Korea.

Background: Central corneal thickness (CCT) and its association with intraocular pressure, which is a pivotal parameter in glaucoma management, has previously been reported. In this study, we intended to investigate the long-term change of CCT in terms of rate in eyes with primary angle-closure (PAC). Additionally, we aimed to analyze events that could affect CCT. Read More

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Aetiology and clinical characteristics of uveitic glaucoma in Turkish patients.

Int Ophthalmol 2021 Jun 17;41(6):2225-2234. Epub 2021 Mar 17.

University of Health Sciences Turkey, Beyoglu Eye Training and Research Hospital, Bereketzade Street Number: 2, Beyoglu, Istanbul, Turkey.

Purpose: To investigate the types, frequency and clinical profiles of uveitic glaucoma seen at a tertiary care center and also to have an idea about the distribution of uveitic glaucoma types in Turkish population.

Methods: Consecutive case notes of all patients attending a specialized uveitis clinic over a 3-month period were reviewed retrospectively.

Results: One hundred and seven eyes of 96 patients were included. Read More

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Bilateral Acute Angle Closure in a Pediatric Patient Taking Lisdexamfetamine Dimesylate (Vyvanse).

J Glaucoma 2021 05;30(5):e259-e261

Vanderbilt Eye Institute.

Attention-deficit/hyperactivity disorder is commonly treated with amphetamines as first line therapy. Rare case reports have shown amphetamines are associated with open angle glaucoma. We report a rare case of a 14-year-old male who presented with bilateral acute angle closure presumed to be related to his use of lisdexamfetamine dimesylate (Vyvanse). Read More

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Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer.

BMJ Case Rep 2021 Feb 23;14(2). Epub 2021 Feb 23.

Ophthalmology, Epsom and Saint Helier Hospital NHS Trust, Carshalton, Sutton, UK.

In this case study, we explore a case of bilateral acute angle closure (AAC) attack detected in a 52-year-old female patient with no other ophthalmic background or predisposition to angle closure, following an increase of her regular sumatriptan dose used for migraine relief. Even though the initial presentation was misinterpreted as migraine attack, it nevertheless alerted the treating physicians to immediate cessation of the drug, allowing for the pertinent ocular symptomatology to be unveiled. Drug-induced bilateral AAC is a rare occurrence and can lead to significant ocular morbidity if not detected and treated early. Read More

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February 2021

Psychotropic Drug-Induced Glaucoma: A Practical Guide to Diagnosis and Management.

CNS Drugs 2021 Mar 19;35(3):283-289. Epub 2021 Feb 19.

Save Sight Institute, University of Sydney, Sydney, NSW, Australia.

This article provides a practical review of the diagnosis and management of angle closure induced by psychotropic agents, including tricyclic antidepressants, antipsychotics and anticonvulsants. Selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, monoamine oxidase inhibitors and antipsychotics may trigger angle closure by influencing pupil configuration through adrenergic, anticholinergic, serotonergic or dopaminergic mechanisms. Patients with narrow iridocorneal angles are at risk, and these are more common in people with hypermetropia (near-sightedness), older people and individuals with an Asian background. Read More

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HSP70 expression before and after treatment and its clinical value in patients with acute angle-closure glaucoma.

Exp Ther Med 2021 Mar 25;21(3):253. Epub 2021 Jan 25.

Department of Glaucoma, Hebei Eye Hospital, Xingtai, Hebei 054000, P.R. China.

The present study aimed to explore the clinical role of heat shock protein 70 (HSP70) in patients with acute angle-closure glaucoma (AACG). Seventy-four AACG patients who were admitted to our hospital from April 2017 to April 2019 were enrolled as a study group (SG). A further 70 healthy people undergoing physical examinations during the same period were enrolled as a control group (CG). Read More

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