13,759 results match your criteria Gingivitis


Interleukin-17 producing T cells and interleukin-17 mRNA expression in periodontitis and longstanding gingivitis lesions.

J Periodontol 2018 Dec 7. Epub 2018 Dec 7.

Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Sweden.

Background: T helper17 cells (Th17) are key targets in the evaluation of differences between "destructive" and "non-destructive" periodontal lesions. The aim of the present study was to analyze the density of interleukin-17 (IL-17) producing T cells and IL-17 mRNA expression in lesions representing severe periodontitis and longstanding gingivitis.

Methods: Two groups of patients were recruited. Read More

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December 2018

Gingival crevicular fluid and salivary HIF-1α, VEGF, and TNF-α levels in periodontal health and disease.

J Periodontol 2018 Dec 11. Epub 2018 Dec 11.

Department of Periodontology, Faculty of Dentistry, Ege University, İzmir, Turkey.

Aim: Hypoxia-inducible factor-1 alpha (HIF-1α) is expressed as an adaptive response to hypoxia, mediates angiogenesis through the expression of vascular endothelial growth factor (VEGF) and can be induced by tumor necrosis factor-alpha (TNF-α). This study aimed to investigate the gingival crevicular fluid (GCF) and salivary HIF-1α, VEGF, and TNF-α levels in periodontal health and disease.

Methods: A total of 87 individuals, 20 generalized aggressive periodontitis (G-AgP), 20 chronic periodontitis (CP), 26 gingivitis patients, and 21 periodontally healthy individuals, were included. Read More

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December 2018

Effect of sonic versus manual supervised toothbrushing on both clinical and biochemical profiles of patients with desquamative gingivitis associated with oral lichen planus: a randomized controlled trial.

Int J Dent Hyg 2018 Dec 2. Epub 2018 Dec 2.

Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.

Objectives: The aim of this randomized, parallel-design, clinical trial was to investigate the effectiveness of an intensive plaque control program with sonic versus manual toothbrushing on clinical outcomes and gingival crevicular fluid (GCF) levels of matrix metalloproteinases (MMP) in desquamative gingivitis (DG) patients.

Methods: A total of 32 patients affected by DG secondary to oral lichen planus (OLP) were consecutively recruited and randomly assigned to a test (n = 16) and control (n = 16) group. Both groups were enrolled in an intensive control program comprising supragingival scaling and polishing, and brush-specific instructions for a period of 8 weeks. Read More

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December 2018
1 Read

Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):809-812

Departamento de Periodontologia, Centro Universitário do Estado do Pará, Belém, PA, Brasil.

Introduction: The influence of cytomegalovirus (CMV) on the progression of chronic periodontitis in HIV patients is poorly investigated.

Methods: ELISA was used for anti-CMV antibody IgG titer measurements and real-time polymerase chain reaction for qualitative and quantitative CMV detection. Data on the CD4 + T lymphocyte count and plasma HIV viral load were obtained from patient records. Read More

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February 2018

A randomized controlled trial of a power brush/irrigator/mouthrinse routine on plaque and gingivitis reduction in orthodontic patients.

Angle Orthod 2018 Dec 5. Epub 2018 Dec 5.

Objectives:: To assess plaque and gingivitis reduction in orthodontic patients after 4 weeks' use of an oscillating-rotating power brush, irrigator, and mouthrinse.

Materials And Methods:: This was a randomized, examiner-blind, clinical trial comparing plaque and gingivitis outcomes for an experimental power brush/irrigator/mouthrinse oral hygiene routine vs a dental prophylaxis followed by regular manual brushing (positive control). Fifty-one participants with fixed orthodontic appliances in the upper and lower jaw and a minimum of 15 gingival bleeding sites were randomly assigned to experimental or positive control treatment. Read More

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December 2018
2 Reads

Diagnosis of a case of ligneous gingivitis in a patient with moderate plasminogen deficiency.

J Stomatol Oral Maxillofac Surg 2018 Dec 1. Epub 2018 Dec 1.

Service d'Odontologie du CHU, 549 avenue du Pr JL Viala, 34295 Montpellier cedex 5, France. Electronic address:

Plasminogen deficiency is a rare congenital condition that leads to pseudomembraneous lesions, such as ligneous conjunctivitis and ligneous gingivitis. Because of its rarity, ligneous gingivitis is not a pathology one may easily suspect from its clinical symptoms. We report the case of a 35-year-old Caucasian woman who experienced gum masses with white spots, but no pain. Read More

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December 2018
2 Reads

Toothbrushing-Should We Advise Mechanical or Power Brushes? Results of an International Delphi Conference.

J Contemp Dent Pract 2018 Oct 1;19(10):1169-1173. Epub 2018 Oct 1.

Procter and Gamble Gulf, Dubai, United Arab Emirates.

Background And Aim: To develop evidence-based answers to a series of questions in relation to toothbrushing using a modified Delphi consensus approach. Oral hygiene and especially toothbrushing have been a fundamental part of the efforts to prevent caries and gingivitis. The questions discussed involved the frequency and duration of brushing, the effectiveness and safety of powered brushes and the recommendations for children and orthodontic patients. Read More

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October 2018

Dental Problems in Primary Care.

Am Fam Physician 2018 Dec;98(11):654-660

University of Louisville School of Dentistry, Louisville, KY, USA.

Oral health directly affects overall health and quality of life. More Americans lack dental insurance than medical insurance. Patients with poor oral health are more likely to have respiratory and cardiovascular diseases, adverse pregnancy outcomes, and diabetes mellitus. Read More

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December 2018

Medicinal and Aromatic Plants Used in Traditional Treatment of the Oral Pathology: The Ethnobotanical Survey in the Economic Capital Casablanca, Morocco (North Africa).

Nat Prod Bioprospect 2018 Nov 27. Epub 2018 Nov 27.

Laboratory of Ecology and Environment, Faculty of Sciences Ben M'sik, University Hassan II Casablanca, Sidi Othman, BP 7955, Casablanca, Morocco.

In order to identify the medicinal and aromatic plants most requested for the treatment of the most common oral pathology, an ethnobotanical survey was carried out in the economic capital Casablanca, Morocco. The data basis was obtained draw selected traditional herbalists based on the semi-structured questionnaire. Quantitative indices such as use value (UV), family UV (FUV), fidelity level and informant consensus factor (ICF) were intended to evaluate the importance of plant species. Read More

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November 2018
1 Read

Efficacy and Tolerability of Sodium Bicarbonate Toothpaste in Subjects with Gingivitis: A 6-Month Randomized Controlled Study.

Oral Health Prev Dent 2018 ;16(5):401-407

Purpose: Sodium bicarbonate (NaHCO3) in toothpaste can enhance the removal of biofilms involved in the development of gingivitis. To examine this over an extended time period, this study compared the efficacy and tolerability of twice-daily brushing for 24 weeks with 67% or 0% NaHCO3-containing toothpastes in subjects with moderate gingivitis.

Materials And Methods: 247 adults with bleeding after brushing and ≥ 20 gingival bleeding sites were randomized to twice-daily brushing with a 67% NaHCO3 or 0% NaHCO3 toothpaste. Read More

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January 2018

Evidence-Based Update on Diagnosis and Management of Gingivitis and Periodontitis.

Authors:
Satish Kumar

Dent Clin North Am 2019 Jan 29;63(1):69-81. Epub 2018 Oct 29.

A.T. Still University, Arizona School of Dentistry and Oral Health, 5855 E Still Circle, Mesa, AZ 85296, USA. Electronic address:

This article is an overview to update the practicing general dental practitioner about clinically relevant evidence-based topics published in the recent past in the diagnosis, etiopathogenesis, and management of gingivitis and periodontitis. Read More

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January 2019

In vitro effects of commercial mouthwashes on several virulence traits of Candida albicans, viridans streptococci and Enterococcus faecalis colonizing the oral cavity.

PLoS One 2018 15;13(11):e0207262. Epub 2018 Nov 15.

Department of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.

Oral microbiota consists of hundreds of different species of bacteria, fungi, protozoa and archaea, important for oral health. Oral mycoses, mostly affecting mucosae, are mainly caused by the opportunistic pathogen Candida albicans. They become relevant in denture-wearers elderly people, in diabetic patients, and in immunocompromised individuals. Read More

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November 2018
4 Reads

Influence of polycystic ovary syndrome on the periodontal health of Indian women visiting a secondary health care centre.

Clin Oral Investig 2018 Nov 14. Epub 2018 Nov 14.

Department of Periodontology, Manipal Academy of Higher Education (MAHE), Manipal College of Dental Sciences, Manipal, 576104, India.

Objectives: Periodontal disease and polycystic ovary syndrome (PCOS) share risk factors like obesity, insulin resistance, and dyslipidemia, along with evidence of chronic inflammation in the two conditions. Evaluating the influence of PCOS on periodontal health would, therefore, identify a possible association.

Materials And Methods: Sixty women, divided into equal groups of PCOS and healthy patients, were clinically examined for periodontal parameters like probing depth (PD), plaque index (PI), modified gingival index (mGI), and bleeding on probing (BOP). Read More

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November 2018
4 Reads
2.352 Impact Factor

Correlation of salivary immunoglobulin A with Body Mass Index and fat percentage in overweight/obese children.

J Appl Oral Sci 2018 Nov 8;27:e20180088. Epub 2018 Nov 8.

Universidade Cruzeiro do Sul, Programa de Pós-Graduação em Odontologia, São Paulo, São Paulo, Brasil.

Obesity is considered a risk factor for periodontal health due to the low- grade inflammation promoted by the increased adipose tissue.

Objective: This study aimed to determine correlations and associations between gingival inflammation (Simplified Oral Hygiene Index, and Gingival Index), salivary immunoglobulin A (s-IgA), and salivary parameters (salivary flow and osmolality) in normal-weight and overweight/obese children.

Material And Methods: Ninety-one children, aged 6 to 12 years old (8. Read More

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November 2018

Reassessing the Role of in Periodontitis.

Front Cell Infect Microbiol 2018 29;8:379. Epub 2018 Oct 29.

Science and Healthcare for Oral Welfare, Toulouse, France.

The protozoan resides in the oral cavity and is frequently observed in the periodontal pockets of humans and pets. This species of is closely related to the human pathogen , the agent of amoebiasis. Although is highly enriched in people with periodontitis (a disease in which inflammation and bone loss correlate with changes in the microbial flora), the potential role of this protozoan in oral infectious diseases is not known. Read More

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October 2018
2 Reads
2.620 Impact Factor

Identification of inflammatory response patterns in experimental gingivitis studies.

Eur J Oral Sci 2018 Nov 9. Epub 2018 Nov 9.

Department of Dentistry and Oral Health, Section of Periodontology, Aarhus University, Aarhus, Denmark.

We used novel analytical approaches to identify inflammatory response patterns to plaque accumulation in experimental gingivitis studies in humans. Data from two experimental gingivitis studies [Dataset I (n = 40) and Dataset II (n = 42)], which differed in design and recording methods, were used. Both studies comprised a three-phase program as follows: pre-induction period (oral hygiene as usual for Dataset I; professional tooth cleaning for Dataset II); induction period (plaque accumulation); and resolution period (oral hygiene as usual). Read More

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November 2018
2 Reads

[Hydrogen rich water attenuates pregnancy gingivitis induced by ligation in SD rats].

Shanghai Kou Qiang Yi Xue 2018 Jun;27(3):252-256

School of Stomatology, Taishan Medical University. Taian 271000, China.

Purpose: To investigate the effect of hydrogen rich water on experimental gingivitis in SD rats during pregnancy.

Methods: Female SD rats mated with male ones were chosen to induce experimental gingivitis after ligation for 2 weeks. The pregnant rats were randomly divided into control group, model group and HW group. Read More

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Gaps in oral health-care service provision systems for children in Nigeria: A case study of a tertiary health institution.

Indian J Dent Res 2018 Sep-Oct;29(5):622-626

Department of Child Dental Health, Faculty of Dentistry, Obafemi Awolowo University, Ile-Ife, Nigeria.

Background: The study investigated the common dental conditions of children seen in a Nigerian tertiary hospital. The referral patterns were also determined to know how many of the patients had sought care at the lower levels of health before visiting a tertiary hospital.

Methods: All the children aged 0-15 years seen at the Dental hospital, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria over a 4-year period were included in the study. Read More

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November 2018
4 Reads

Histological and inflammatory analysis to diagnostic method of proximal gingivitis by flossing.

Clin Oral Investig 2018 Nov 6. Epub 2018 Nov 6.

Department of Pathology, Oral Pathology, School of Dentistry, Federal University of Santa Maria - UFSM, Santa Maria, Rio Grande do Sul, Brazil.

Objectives: The aim of this study was to assess with histological and inflammatory analysis the use of flossing as a diagnostic method for detecting proximal gingivitis.

Material And Methods: This is a diagnostic accuracy paper composed of two different studies. In the first study, three groups were identified based on papilla status: bleeding (+) with both methods (N = 26); bleeding (+) with dental floss, but no bleeding (-) with probing (N = 26); and no bleeding (-) with either method (N = 26). Read More

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November 2018
2 Reads

Therapeutic benefits of liquorice in dentistry.

J Ayurveda Integr Med 2018 Oct 31. Epub 2018 Oct 31.

Faculty of Dentistry, SEGi University, Kota Damansara, Malaysia.

Oral health influences general well-being and quality of life. Oral diseases can be debilitating and are a major heath concern worldwide. Medicinal plants have been used for thousands of years for treating human diseases. Read More

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October 2018
4 Reads

Effectiveness of Herbal Mouthwash among Visually Impaired Residential School Students.

JNMA J Nepal Med Assoc 2018 Jul-Aug;56(212):728-734

Department of Public Health Dentistry, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Introduction: Visually impaired patients are unable to visualize the plaque on tooth surfaces resulting in inadequate plaque removal and therefore the progression of dental caries and inflammatory disease of the periodontium. The objective of the study was to assess the effectiveness of herbal mouth wash in reduction of plaque and gingivitis among visually impaired children.

Methods: Randomized controlled clinical trial was conducted with parallel groups study, comprising 6 to 20 year old visually impaired children, 20 in each group (herbal mouth wash or chlorhexidine mouthwash or placebo mouthwash). Read More

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November 2018
8 Reads

Reduced ADAM8 levels upon non-surgical periodontal therapy in patients with chronic periodontitis.

Arch Oral Biol 2019 Jan 23;97:137-143. Epub 2018 Oct 23.

Department of Restorative Dentistry and Periodontology, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand; Center of Excellence in Oral and Maxillofacial Biology, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:

Objective: To determine effect of non-surgical periodontal treatment on a disintegrin and metalloproteinase 8 (ADAM8) levels in gingival crevicular fluid (GCF) of patients with chronic periodontitis (CP) in comparison with those of patients with gingivitis and to find correlations between ADAM8 levels and clinical parameters.

Design: Twenty-two and eleven patients with CP and gingivitis, respectively, were examined for four clinical parameters, probing depth, clinical attachment level, gingival and plaque indices. GCF from the selected gingivitis or periodontitis sites with distinct severities was sampled by Periopaper strips. Read More

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January 2019
1 Read

One-to-one oral hygiene advice provided in a dental setting for oral health.

Cochrane Database Syst Rev 2018 10 31;10:CD007447. Epub 2018 Oct 31.

Community Dental Service, Bradford District Care NHS Foundation Trust, Bradford, UK.

Background: Effective oral hygiene measures carried out on a regular basis are vital to maintain good oral health. One-to-one oral hygiene advice (OHA) within the dental setting is often provided as a means to motivate individuals and to help achieve improved levels of oral health. However, it is unclear if one-to-one OHA in a dental setting is effective in improving oral health and what method(s) might be most effective and efficient. Read More

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October 2018
2 Reads

Edema and gingival bleeding in anterior region have a negative influence on quality of life of adolescents.

Braz Oral Res 2018 Oct 25;32:e112. Epub 2018 Oct 25.

Universidade Federal de Santa Maria - UFSM, Faculty of Dentistry, Department of Stomatology, Santa Maria, RS, Brazil.

The aim of the present study was to verify if clinical signs of gingivitis such as color changes, edema, and bleeding in the anterior region influence the OHRQoL of adolescents. We followed a cross-sectional convenience sample of 67 adolescents aged 11 to 16 years receiving dental treatment at the Federal University of Santa Maria (UFSM), in southern Brazil. The participants were evaluated for the following clinical variables: edema, gingival color alteration, and marginal bleeding of the gingival tissues, collected at 6 sites per tooth in the anterior region of the mouth. Read More

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October 2018
2 Reads

A 5-Week Randomized Clinical Evaluation of a Novel Electric Toothbrush Head with Regular and Tapered Bristles versus a Manual Toothbrush for Reduction of Gingivitis and Plaque.

Int J Dent Hyg 2018 Oct 29. Epub 2018 Oct 29.

All Sum Research Center Ltd, Mississauga, Canada.

Objective: To evaluate the efficacy of an oscillating-rotating (O-R) electric rechargeable toothbrush with a novel round brush head comprised of regular and tapered bristles in reducing plaque and gingivitis versus a manual toothbrush.

Methods: This was a randomized, examiner-blind, parallel group, five-week study. Participants with mild-to-moderate plaque and gingivitis received an oral examination and were evaluated for baseline plaque (Rustogi Modified Navy Index), gingivitis (Modified Gingival Index), and gingival bleeding (Gingival Bleeding Index). Read More

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October 2018
22 Reads

Therapeutic efficacy of chlorhexidine-based mouthwashes and its adverse events: performance-related evaluation of mouthwashes added with Anti-Discoloration System and cetylpyridinium chloride.

Int J Dent Hyg 2018 Oct 29. Epub 2018 Oct 29.

Department of Oral and Maxillo-Facial Sciences, "Sapienza" University of Rome, Rome, Italy.

Objectives: To compare 3 mouthwashes: 0.20%chlorhexidine-CHX- with Anti-Discoloration-System-ADS, 0.20%CHX, 0. Read More

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October 2018
6 Reads
0.682 Impact Factor

[Cheilitis granulomatosa revealing Crohn's disease].

Pan Afr Med J 2018 20;30:147. Epub 2018 Jun 20.

Service d'Hépato-gastroentérologie, Faculté de Médecine et de Pharmacie de Fès, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Many disorders of the digestive tract cause cutaneous manifestations that may be an indication of an underlying condition; hence dermatologist plays a key role in recommending that the patient see a gastroenterologist. Conversely, gastroenterologist often sees patients with mucocutaneous lesions suggesting possible association with well-known digestive disorders. Chronic inflammatory bowel diseases are the typical example of this essential collaboration between the two specialities. Read More

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November 2018
1 Read

Periodontal Disease and Pregnancy Outcomes: Overview of Systematic Reviews.

JDR Clin Trans Res 2018 Jan 25;3(1):10-27. Epub 2017 Sep 25.

Department of Paediatrics, Maastricht University Medical Centre, Maastricht, Netherlands.

Periodontal disease is very common during pregnancy. Although it has been linked to adverse pregnancy outcomes, systematic reviews have reached discrepant conclusions on these links. Therefore, we conducted a systematic overview of systematic reviews studying the association between periodontal disease and adverse pregnancy outcomes. Read More

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January 2018
2 Reads

Oral Lichenoid Lesion Manifesting as Desquamative Gingivitis: Unlikely Association? Case Report.

Open Dent J 2018 28;12:679-686. Epub 2018 Sep 28.

Department of Pathology, Faculty of Dentistry, Cesmac University Center, Cônego Machado, 918, Farol CEP: 57051-160, Maceió, Alagoas, Brazil.

Introduction: The aim of this report is to present a clinical case of oral lichenoid lesions associated with amalgam restorations with the presence of desquamative gingivitis for a nine months follow up period.

Case Report: The histopathologic characteristics and direct immunofluorescence were compatible with Oral Lichenoid Lesion (LLO). Diagnosis was based on a synthesis of all available information, including medical history, clinical examination, histopathology and the results of specific tests, such as the patch test, which confirmed allergy to thimerosal, an organic compound of mercury. Read More

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September 2018
1 Read

Immune response mediated by Th1 / IL-17 / caspase-9 promotes evolution of periodontal disease.

Arch Oral Biol 2019 Jan 19;97:77-84. Epub 2018 Sep 19.

Graduate Program in Biomedical Sciences, Centro Universitario Hermınio Ometto (UNIARARAS), Brazil. Electronic address:

Introduction: Periodontitis is characterized by inflammatory mediators beyond T lymphocyte function and phenotype (Th1/Th2/Th17). The clinical diversity in periodontitis makes it difficult to characterize the immune response in patients. This study evaluated the profile of the adaptive immune response in the periodontal disease model. Read More

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January 2019
3 Reads

Five hundred patients reporting on adverse effects from dental materials: Frequencies, complaints, symptoms, allergies.

Dent Mater 2018 Dec 22;34(12):1756-1768. Epub 2018 Oct 22.

University of Regensburg Medical Center, Department of Conservative Dentistry and Periodontology, 93042 Regensburg, Germany.

Objective: Information on patients with real or claimed adverse reactions towards dental materials in large patient cohorts is rare. Therefore, the aim of the present study was to investigate patients reporting on complaints and symptoms to dental materials over a 16-year period.

Methods: Five hundred patients were characterized by one single dental team regarding age and sex distribution, subjective complaints and objective intraoral symptoms, and allergy status relevant to dental materials. Read More

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December 2018
2 Reads

Evaluation of the efficacy of the subcutaneous low recombinant feline interferon-omega administration protocol for feline chronic gingivitis-stomatitis in feline calicivirus-positive cats.

Res Vet Sci 2018 Dec 12;121:53-58. Epub 2018 Oct 12.

Division of Therapeutic Sciences I, Department of Veterinary Clinical Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan.

We investigated the clinical effectiveness of subcutaneous (SC) administration of recombinant feline interferon-omega (rFeIFN-ω) at a dose of 1 M unit (MU)/kg body weight (bw) for the treatment of feline chronic gingivitis-stomatitis (FCGS) in cats infected with feline calicivirus (FCV). Among the 17 cats used in this study, there were 13 FCV-positive cats (FCVI group), which were subcutaneously injected with rFeIFN-ω. The remaining four FCV-positive cats (FCVC group) were treated with SC corticosteroid. Read More

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December 2018
9 Reads

Keystone Species in Pregnancy Gingivitis: A Snapshot of Oral Microbiome During Pregnancy and Postpartum Period.

Front Microbiol 2018 9;9:2360. Epub 2018 Oct 9.

Discipline of Oral Sciences, Faculty of Dentistry, National University of Singapore, Singapore, Singapore.

It is well known that pregnancy is under the constant influence of hormonal, metabolic and immunological factors and this may impact the oral microbiota toward pregnancy gingivitis. However, it is still not clear how the oral microbial dysbiosis can modulate oral diseases as oral microbiome during pregnancy is very poorly characterized. In addition, the recent revelation that placental microbiome is akin to oral microbiome further potentiates the importance of oral dysbiosis in adverse pregnancy outcomes. Read More

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October 2018
3 Reads

The Relationship between Vitamin D and Periodontal Pathology.

Medicina (Kaunas) 2018 Jun 12;54(3). Epub 2018 Jun 12.

Faculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, A. Mickevičiaus 9, Kaunas LT-44307, Lithuania.

Osteoporosis and periodontal diseases are common problems among the elderly population. Vitamin D is a secosteroid hormone that is either synthesized by human skin cells under the effect of UV radiation or consumed through diet. Deficiency in vitamin D leads to reduced bone mineral density, osteoporosis, the progression of periodontal diseases and causes resorption to occur in the jawbone. Read More

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June 2018
5 Reads

Consumption of cranberry functional beverage reduces gingival index and plaque index in patients with gingivitis.

Nutr Res 2018 Oct 4;58:36-45. Epub 2018 Jul 4.

Institute of Human Nutrition and Dietetics, Poznan University of Life Sciences, Poland.

Periodontal disease is highly prevalent worldwide, and consumption of certain foods, such as fruits, seem to improve the effectiveness of periodontal therapy (PT) due to their antiadhesive, immunomodulatory, and antioxidative properties. We hypothesized that the cranberry functional beverage (CFB) consumed for eight weeks improves gingival inflammation indices via inhibition of dental plaque, and alterations in antioxidant status, and systemic inflammation in patients with gingivitis. In this two-arm randomized controlled study, fifty participants were divided into an experimental group (CFB), administered daily with 750 ml CFB, or a control group administered the same amount of water. Read More

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October 2018
1 Read

A Conservative Approach for Localized Spongiotic Gingivitis Hyperplasia Using Photodynamic Therapy: A Case Report and Review of the Literature.

Photomed Laser Surg 2018 Oct 18. Epub 2018 Oct 18.

1 Department of Dentistry, Faculty of Health Sciences, University of Brasília , Brasília, Brazil .

Objective: To describe a clinical case of successful conservative management of Localized Juvenile Spongiotic Gingivitis Hyperplasia (LJSGH) using photodynamic therapy (PDT) and reviews the current literature on this pathology.

Background Data: LJSGH is a recently described rare disease with controversial treatment results. As of today, 13 publications report surgical treatment approaches. Read More

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October 2018

Clinical results of improvement in periodontal condition by administration of oral probiotics.

J Biol Regul Homeost Agents 2018 Sep-Oct;32(5):1329-1334

Department of Interdisciplinary Medicine, School of Medicine, University of Bari Aldo Moro, Bari, Italy.

Dental plaque-related diseases (cavities, gingivitis, periodontitis and halitosis) have been traditionally controlled by mechanical non-specific removal of plaque. However, many novel treatment approaches aim to inhibit the growth of pathogenic bacteria or to remove their toxins. Probiotics are viable microorganisms which, when administered in adequate amounts, provide a health benefit to the host. Read More

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October 2018

Self-reported oral status and habits related to oral care in adult Poles: A questionnaire study.

Dent Med Probl 2018 Jul-Sep;55(3):313-320

Department of Periodontology and Oral Diseases, Medical University of Warsaw, Poland.

Background: Bacterial plaque control plays a key role in the prevention of caries and periodontal diseases. Hygiene negligence in this respect may influence the state of gingiva, and - in the long term - the number of lost teeth. The recommended method of mechanical control of dental plaque is tooth brushing twice a day. Read More

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October 2018

Effect of a structured plaque control on MMP-1 and MMP-9 crevicular levels in patients with desquamative gingivitis associated with oral lichen planus.

Clin Oral Investig 2018 Oct 16. Epub 2018 Oct 16.

Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Via Nizza 230, 10126, Turin, Italy.

Objectives: No data are available in the literature on the extent to which the immune host-response and bacterial-elicited inflammation separately contributes to the increase in gingival crevicular fluid (GCF) levels of inflammatory biomarkers in patients affected by desquamative gingivitis (DG) secondary to oral lichen planus (OLP). The aim of this study was to investigate the effect of a structured plaque control intervention on GCF levels of MMP-1 and MMP-9 in OLP patients with DG and to compare them with those of non-OLP patients.

Materials And Methods: The study population consisted of 18 unrelated Caucasian patients with DG, while 18 periodontally healthy subjects were recruited for the control group. Read More

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October 2018

[Oral allergies].

Authors:
L Evrard

Rev Med Brux 2018;39(4):317-321

Service de Dentisterie - Chirurgie orale et maxillo-faciale - Orthodontie - Stomatologie, Hôpital Erasme, ULB.

Oral allergies to dental materials are a growing problem and remain poorly diagnosed by health professionals. The complaints of patients with oral allergy are various and include sensations of burning or stinging of the oral mucosa, sensations of dryness of the oral cavity, or general symptoms such as headache, dyspepsia, asthenia, arthralgia, and myalgia. Signs suggestive of oral allergy include erythema, edema, purpuric patches on the palate, ulcerations of the oral mucosa (canker sore), gingivitis, glossitis mimicking geographic tongue, angular cheilitis, peri-oral eczema or the presence of lichenoid reactions of the oral mucosa. Read More

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December 2018

Ketotifen fumarate attenuates feline gingivitis related with gingival microenvironment modulation.

Int Immunopharmacol 2018 Dec 10;65:159-173. Epub 2018 Oct 10.

Beijing Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences, Beijing 100193, People's Republic of China. Electronic address:

Gingivitis is evidenced by inflammation of the free gingiva, and still reversible. If left untreated, it may then progress to periodontitis. In the present study, the therapeutical effect of ketotifen fumarate on gingivitis was explored. Read More

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December 2018
1 Read
2.470 Impact Factor

Characterization and comparison of neutrophil extracellular traps in gingival samples of periodontitis and gingivitis: A pilot study.

J Periodontal Res 2018 Oct 8. Epub 2018 Oct 8.

Periodontology Department, School of Dentistry, University of Granada, Granada, Spain.

Background And Objective: Neutrophil extracellular traps (NETs) are a recently discovered antimicrobial mechanism used by neutrophils that have been proposed as an intervention in the pathogenesis of periodontitis. The objective of our study was to characterize the expression of NETs in gingival tissues with periodontitis and controls and to compare the expression of these traps in gingival tissue samples of patients with gingivitis and periodontitis.

Material And Methods: An observational cross-sectional study was conducted on patients with periodontitis, gingivitis, and controls that needed tooth extraction. Read More

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October 2018

Are dairy products containing probiotics beneficial for oral health? A systematic review and meta-analysis.

Clin Oral Investig 2018 Nov 9;22(8):2763-2785. Epub 2018 Oct 9.

Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal do Rio de Janeiro, Rua Prof. Rodolpho Paulo Rocco, 325, Cidade Universitária, Rio de Janeiro, RJ, 21941-617, Brazil.

Objectives: To evaluate the effect of probiotic containing in dairy products on oral and salivary parameters.

Material And Methods: Electronic searches were performed based on the PICO criteria. Randomized controlled trials in adults/children (P) in which dairy products containing probiotics (I) were compared to controls (C) for establishment of oral health (O) were included. Read More

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November 2018
4 Reads

Correlation between the DAI and ICON Indices used for Assessment of Orthodontic Treatment need in Croatian Schoolchildren.

Zdr Varst 2018 Dec 1;57(4):218-226. Epub 2018 Oct 1.

University of Rijeka, School of Medicine, Department of Orthodontics, Krešimirova 40, 51000 Rijeka, Croatia.

Introduction: The aims were: evaluation of the correlation between the Dental Aesthetic Index (DAI) and Index of Complexity, Outcome and Need (ICON); the assessment of orthodontic treatment need for schoolchildren in a population with two indices, separately for schoolchildren with mixed and permanent dentition; the estimation of the population share that could not receive orthodontic treatment because of the presence of caries and/or gingivitis.

Methods: A total of 2652 Zagreb school children (7 - 19 years old, 52.4% of them were females) completed a questionnaire regarding previous orthodontic treatment and the type of appliance used. Read More

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December 2018

Oral health and microbiota status in professional rugby players: A case-control study.

J Dent 2018 Dec 5;79:53-60. Epub 2018 Oct 5.

INSERM U1048, F-31432 Toulouse, France, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), F-31432 Toulouse, France; Université Paul Sabatier III (UPS), F-31432 Toulouse, France; CHU Toulouse, Service d'Odontologie Toulouse, F-3100, France. Electronic address:

Objective: Elite athletes are prone to develop oral diseases, which could increase the risk for injuries. The aim of this study was to evaluate the oral health and the composition of oral microbiota of elite rugby players compared to the general population.

Methods: We set up a case-control study by screening 24 professional rugby players (PRG) and 22 control patients (CG) for dental and gingival examinations and performed a taxonomic analysis and a predicted functional analysis of oral microbiota. Read More

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December 2018
3 Reads

Macrophage polarization in human gingival tissue in response to periodontal disease.

Oral Dis 2018 Oct 4. Epub 2018 Oct 4.

State Key Laboratory of Military Stomatology, Department of Periodontology, School of Stomatology, National Clinical Research Center for Oral Diseases, Fourth Military Medical University, Xi'an, China.

Objective: Although accumulating evidence indicates that macrophages are central players in the destructive and reparative phases of periodontal disease, their polarization states at different stages of periodontal inflammation remain unclear.

Methods: We collected gingival biopsies from patients with chronic periodontitis (P group), gingivitis (G group), or periodontally healthy individuals (H group). Polarized macrophages were identified through immunofluorescence. Read More

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October 2018
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A genome-wide association study identifies an association between variants in EFCAB4B gene and periodontal disease in an Italian isolated population.

J Periodontal Res 2018 Dec 4;53(6):992-998. Epub 2018 Oct 4.

Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Trieste, Italy.

Background And Objective: Periodontitis in one of the most prevalent dental diseases. Despite numerous studies have investigated its aetiopathogenetic factors, few works have focused on its genetic predisposition and most of them took into account only candidate genes. Therefore, we conducted a Genome Wide Association Study in an Italian isolated population aimed at uncovering genetic variants that predispose to this disorder. Read More

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December 2018

Oral health status of pregnant and puerperal women in the municipality of Feira de Santana, at three different times between 2005 and 2015.

Epidemiol Serv Saude 2018 09 21;27(3):e2017273. Epub 2018 Sep 21.

Universidade Estadual de Feira de Santana, Departamento de Saúde, Feira de Santana, BA, Brasil.

Objective: to evaluate the oral health condition of pregnant/postpartum women attending public services in the city of Feira de Santana, BA, Brazil, at three different times between 2005 and 2015.

Methods: this is a study socioeconomic and demographic characteristics, health condition and health care, lifestyle and oral health status of 1,245 participants obtained from a database of three previous investigations: I Intervention Study (2005-2007); II Case-Control Study (2010-2011); III Case-Control Study (2012-2015).

Results: comparing the three periods, the frequency of gingivitis (24. Read More

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September 2018
1 Read

The role of poor oral health in surgical site infection following elective spinal surgery.

Musculoskelet Surg 2018 Sep 29. Epub 2018 Sep 29.

School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Study Design: Cross-sectional study.

Objectives: To describe oral health and hygiene as a risk factor for surgical site infection (SSI).

Methods: This cross-sectional study was conducted on patients over 18 years of age who were candidates for elective spinal surgery. Read More

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September 2018
6 Reads

Do total or partial etching procedures effect the rate of white spot lesion formation?: A single-center, randomized, controlled clinical trial.

Angle Orthod 2018 Sep 27. Epub 2018 Sep 27.

Objective:: To determine whether total or partial etching procedures influence the appearance of white spot lesions (WSLs).

Materials And Methods:: This split-mouth, double-blind, controlled, randomized study included 20 patients (mean age 16.75 years), who had class I malocclusion, mild crowding, and satisfactory oral hygiene. Read More

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September 2018