9,237 results match your criteria Ginekologia polska[Journal]


Randomized comparison of two methods of the epidural space identification during regional labour analgesia.

Ginekol Pol 2019 Apr 15. Epub 2019 Apr 15.

1st Chair and Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: Conventional loss of resistance (LOR) technique for identifying the epidural space (EDS) predominantly depends on experience of the anaesthetist. A technique using automated syringe for EDS identification was invented as an alternative to the traditional method. The aim of the study was to compare the efficacy and risk for complications between automatic LOR syringe - Epimatic® (Vygon, Ecouen, France) and conventional LOR - Perifix® (B. Read More

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http://dx.doi.org/10.5603/GP.a2019.0044DOI Listing

The expression of Platelet-Derived Growth Factor Receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer.

Ginekol Pol 2019 Apr 12. Epub 2019 Apr 12.

Department of Neurochemistry and Neuropathology, Poznan University of Medical Sciences, Poznan, Poland.

Objectives: The main aim of the study was to investigate the expression of Platelet-Derived Growth Factor Receptors alpha (PDGFR-alpha) and beta (PDGFR-beta) in malignant and benign ovarian tumors. We performed an analysis of the correlation of PDGFRs expression and stage of the disease, tumor grade and histopathological type of epithelial ovarian cancer (EOC). Additionally, we evaluated patient prognosis according to PDGFR expression. Read More

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http://dx.doi.org/10.5603/GP.a2019.0045DOI Listing
April 2019
3 Reads

Prognostic value of tissue plasminogen activator (tPA) in patients with epithelial ovarian cancer undergoing chemotherapy.

Ginekol Pol 2019 Apr 10. Epub 2019 Apr 10.

2nd Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: Tissue plasminogen activator (tPA) is a key enzyme for fibrin degradation and the proteolytic defense against formation of the thrombotic endothelial deposits. tPA is involved in carcinogenesis but its exact role in tumor biology is not very well understood and a prognostic value of tPA remains ambiguous in different cancers. The aim of the study was to assess the prognostic value of plasma tPA in patients with epithelial ovarian cancer (EOC) in the course of the first line chemotherapy. Read More

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http://dx.doi.org/10.5603/GP.a2019.0043DOI Listing
April 2019
1 Read

Perinatal care in a patient with diagnosed Westphal's disease.

Ginekol Pol 2019 ;90(3):177

Department of Obstetrics and Gynecology, Dictrict Public Hospital in Poznan, Poland.

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http://dx.doi.org/10.5603/GP.2019.0031DOI Listing
January 2019

The role of disordered angiogenesis tissue markers (sflt-1, Plgf) in present day diagnosis of preeclampsia.

Ginekol Pol 2019 ;90(3):173-176

Clinical Department of Obstetrics and Gynecology, Pomeranian Medical University in Szczecin, Poland.

Preeclampsia and conditions associated with impaired placental perfusion develop in almost 10% of all pregnancies. Patho- logic angiogenesis is one of the processes observed in preeclampsia. sFlt-1, PlGF and the sFlt-1/PlGF ratio are new and promising angiogenesis-related biomarkers. Read More

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http://dx.doi.org/10.5603/GP.2019.0030DOI Listing
January 2019

The role of artificial nutrition in gynecological cancer therapy.

Ginekol Pol 2019 ;90(3):167-172

Department of Gynecology, Obstetrics and Gynecologic Oncology, Division of Gynecologic Oncology, Poznan University of Medical Sciences, Poznan, Poland.

Cancer patients are at risk of developing malnutrition from underlying disease as well as from cancer treatment. Moreover, weight loss is considered as a predictive factor for disease progression and shorter survival time. As many as 10-20% of patients with cancer die from the results of malnutrition, instead of from the cancer itself. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0027DOI Listing
January 2019
2 Reads

The clinical usefulness of biochemical (free β-hCg, PaPP-a) and ultrasound (nuchal translucency) parameters in prenatal screening of trisomy 21 in the first trimester of pregnancy.

Ginekol Pol 2019 ;90(3):161-166

Chair and Department of Laboratory Analyses, Poznan University of Medical Sciences, Poznan, Poland.

Objectives: The aim of the study was to analyze the correlation of multiples of the normal median of PAPP-A, free β-hCG levels and nuchal translucency values in prenatal, first trimester screening of trisomy 21 in pregnant women.

Material And Methods: 251 pregnant women underwent antenatal screening at 11-13+6 weeks of pregnancy which was composed of the measurement of free β-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein (PAPP-A) levels in the maternal serum and an ultrasound assessment of nuchal translucency (NT). The pregnant women with a high risk of trisomy 21 (≥ 1:300) were given amniocentesis to verify fetal defects. Read More

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http://dx.doi.org/10.5603/GP.2019.0029DOI Listing
January 2019
1 Read

Continuous subcutaneous insulin infusion reduces neonatal risk in pregnant women with type 1 diabetes mellitus.

Ginekol Pol 2019 ;90(3):154-160

Department of Reproduction, Poznan University of Medical Sciences, Poznan, Poland.

Objectives: An attempt was made to demonstrate the superiority of the treatment model using continuous subcutaneous insulin infusion (CSII) over multiple daily injections (MDI) of insulin in achieving a successful pregnancy outcome and good newborn's condition in patients with type 1 diabetes.

Material And Methods: The study included 297 infants born to type 1 diabetic patients; 175 patients were treated with MDI and 122 with CSII. Maternal metabolic control during pregnancy, gestational weight gain, insulin requirements, pregnancy outcome and neonatal status were compared between MDI and CSII arm. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0028DOI Listing
January 2019
4 Reads

Long-term outcomes of prenatally diagnosed ventriculomegaly - 10 years of Polish tertiary centre experience.

Ginekol Pol 2019 ;90(3):148-153

1st Chair and Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: To estimate the prevalence, associated anomalies, and postnatal outcomes in infants prenatally diagnosed with ventriculomegaly.

Material And Methods: All cases of ventriculomegaly that were examined and treated by the 1st Department of Obstet- rics and Gynecology, at the Medical University of Warsaw, from August 2007 until November 2017 were included in this study. Ultrasound data, and information on perinatal outcomes and long-term postnatal follow up were retrospectively collected by a standardised telephone survey. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0026DOI Listing
January 2019
2 Reads

The value of an initial drop in human Chorionic gonadotropin levels in predicting a response to methotrexate in women with low-risk gestational trophoblastic neoplasia.

Ginekol Pol 2019 ;90(3):141-147

Department of Gynecology, Obstetrics and Gynecologic Oncology, Division of Gynecologic Oncology, Poznan University of Medical Sciences, Poznan, Poland.

Objectives: The early identification of patients who are being treated for low-risk gestational trophoblastic neoplasia (LRGTN) with single-agent chemotherapy, who are at high risk of developing chemoresistance, is of crucial importance. The aim of our research was to evaluate the pretreatment beta subunit of human chorionic gonadotropin (βhCG) concentration and its decrease after the administration of the first course of methotrexate (MTX) in predicting later chemo-resistance to single-agent chemotherapy.

Material And Methods: A total of 46 patients diagnosed with LRGTN treated with a 5-day methotrexate (MTX) regimen were retrospectively studied. Read More

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http://dx.doi.org/10.5603/GP.2019.0025DOI Listing
January 2019

The potential predictive value of serum srCaS1 levels for overall survival in endometrial cancer.

Ginekol Pol 2019 ;90(3):134-140

Center of Oncology, M. Sklodowska-Curie Memorial Institute, Cracow Branch, Poland.

Objectives: The main aim of the study was to evaluate the impact of levels of serum soluble receptor-binding cancer antigen expressed on SiSo cells (sRCAS1) on the overall survival (OS) rates in patients with endometrial cancer. Furthermore, we analyzed sRCAS1 levels according to the clinicopathological characteristics of the disease.

Material And Methods: The study group comprised 43 patients who were being treated for endometrial cancer. Read More

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http://dx.doi.org/10.5603/GP.2019.0024DOI Listing
January 2019

Can preoperative magnetic resonance imaging replace intraoperative frozen sectioning in the evaluation of myometrial invasion for early-stage endometrial carcinoma?

Ginekol Pol 2019 ;90(3):128-133

Department of Gynecologic Oncology,University of Health Sciences Tepecik Education and Research Hospital, İzmir, Turkey.

Objectives: To examine the performance of preoperative magnetic resonance imaging (MRI) and intraoperative frozen sectioning in the assessment of myometrial invasion during the early stages of endometrial cancer.

Material And Methods: This retrospective study employed data from patients with endometrial cancer who were operated on between January 2013 and November 2018. Patients who underwent preoperative MRI and were of FIGO 2009 stage I were included in the study. Read More

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http://dx.doi.org/10.5603/GP.2019.0023DOI Listing
January 2019
3 Reads

Underestimation of breast cancer in intraductal papillomas treated with vacuum-assisted core needle biopsy.

Ginekol Pol 2019 ;90(3):122-127

University Center for Breast Diseases, University Hospital in Cracow, Poland.

Objectives: The aims of the study were as follows: 1) to determine the applicability of vacuum-assisted core needle biopsy in the diagnosis and management of intraductal papillomas of the breast; 2) to define factors which increase the risk for underestimation of breast cancer.

Material And Methods: Between 2002-2017, a total of 222 cases of intraductal papillomas were diagnosed in one center (201 using vacuum-assisted core-needle ultrasound-guided biopsy and 21 using stereotactic biopsy). All patients under- went scheduled follow-up imaging. Read More

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http://dx.doi.org/10.5603/GP.2019.0022DOI Listing
January 2019
1 Read

Is copeptin a new potential biomarker of insulin resistance in polycystic ovary syndrome?

Ginekol Pol 2019 ;90(3):115-121

Pomeranian Medical University in Szczecin, Poland.

O: BJECTIVES: Copeptin has been reported to play an important role in metabolic response in women with PCOS. However, the optimal cut-off value for detecting subjects with insulin resistance (IR) remains undetermined. We investigated whether copeptin can serve as an indicator of IR and tried to determine the optimal cut-off value of plasma copeptin concentration in detecting subjects with PCOS and IR. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0021DOI Listing
January 2019
2 Reads

The effects of threatened abortions on pregnancy outcomes.

Ginekol Pol 2019 Mar 22. Epub 2019 Mar 22.

Izmir provincial health directorate, Izmir, Turkey, Turkey.

Objectives: The effects of first trimester threatened abortions on prenatal and postnatal pregnancy outcomes.

Material And Methods: Data from 24.835 pregnant women were retrospectively analysed. Read More

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http://dx.doi.org/10.5603/GP.a2019.0035DOI Listing
March 2019
2 Reads

Exploring the fetal brain: is Mri always better than ultrasound?

Ginekol Pol 2019 ;90(2):114

The 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

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http://dx.doi.org/10.5603/GP.2019.0020DOI Listing
January 2019

The role of lymphocytes in fetal development and recurrent pregnancy loss.

Ginekol Pol 2019 ;90(2):109-113

Department of Reproductive Health, Centre of Postgraduate Medical Education, Warsaw, Poland.

Fetal survival and development is supported by the maternal immune system. Questions regarding those mechanisms have risen from development of transplantation medicine and observation of graft rejection. Initial theories of anatomic division, fetal immune immaturity and maternal immune system inertia were found incorrect. Read More

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http://dx.doi.org/10.5603/GP.2019.0019DOI Listing
January 2019
1 Read

Food and drug administration - approved molecular methods for detecting human papillomavirus infection.

Ginekol Pol 2019 ;90(2):104-108

Department of Virology, Chair of Microbiology, Jagiellonian University Medical College, Cracow, Poland.

In the world, there are many tests that allow the detection of HPV infection. These tests are based on different operating principles and have different levels of sensitivity. The first test to detect HPV infection was approved by the Food and Drug Administration in 2003. Read More

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http://dx.doi.org/10.5603/GP.2019.0018DOI Listing
January 2019

Intraductal papilloma of the breast - management.

Ginekol Pol 2019 ;90(2):100-103

University Center for Breast Diseases, University Hospital in Cracow, Poland.

In light of the growing availability of ultrasound testing and invasive diagnostic methods of the breast in everyday gyneco- logic practice, lesions of uncertain malignant potential, classified histologically as B3, have become a significant health issue. Intraductal papillomas (IPs) are the most common pathology in that group of lesions. Despite their benign histologic appearance, IPs may accompany malignant growths and the diagnosis made on the basis of biopsy material carries the risk of breast cancer (BC) underestimation. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0017DOI Listing
January 2019
11 Reads

Follow-up of children with antenatally diagnosed idiopathic polyhydramnios.

Ginekol Pol 2019 ;90(2):93-99

Division of Reproduction, Department of Gynecology and Obstetrics, Poznan University of Medical Sciences, Poland.

Objectives: The aim of our work was to assess the development of children with antenatally diagnosed idiopathic poly- hydramnios, over 12 months from the end of pregnancy.

Material And Methods: The study included 91 healthy pregnant patients with idiopathic polyhydramnios. Diagnostic tests results and perinatal medical history were obtained retrospectively. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0016DOI Listing
January 2019
7 Reads

Expression of Cripto-1 in the placenta and its role in placenta accreta and placenta previa.

Ginekol Pol 2019 ;90(2):86-92

Fujian Provincial Maternity and Children's Hospital, affiliated hospital of Fujian Medical University, Fuzhou, Fujian, China.

Objectives: This study Aims to explore the role of placental Cripto-1 in the incidence of an adherent placenta.

Material And Methods: Ten pregnant women with placenta increta, 20 pregnant women with placenta previa and 30 women with normal pregnant were enrolled in this study. Reverse transcription-polymerase chain reaction (RT-PCR) was used to measure the expression of Cripto-1 in the placenta while as the analysis of placental Cripto-1 was performed by Western blotting RESULTS: The placenta increta group showed higher levels of Cripto-1 in the center of the increta as compared to the non-implantation area. Read More

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http://dx.doi.org/10.5603/GP.2019.0015DOI Listing
January 2019
1 Read

Additional secure circular suture during sphincteroplasty - preliminary results on the efficacy of fecal incontinence surgery in urogynecological patients.

Ginekol Pol 2019 ;90(2):82-85

II Chair and Department of Gynaecology, Medical University of Lublin, Poland.

Objectives: The paper is a ten case series study presenting women with complex pelvic floor disorders involving fecal incontinence (FI) with stress urinary incontinence or pelvic organ prolapse. Our study aimed at ascertaining whether FI-induced sphincteroplasty with an additional secure circular suture around the external anal sphincter muscle (EAS) may improve long term success rates.

Materials And Methods: Twelve patients had scheduled urogynecological surgery and overlapping sphincteroplasty with the placement of an additional circular suture around the EAS. Read More

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http://dx.doi.org/10.5603/GP.2019.0014DOI Listing
January 2019
1 Read

MTHFR genetic polymorphism and the risk of intrauterine fetal death in Polish women.

Ginekol Pol 2019 ;90(2):76-81

Division of Perinatology and Women's Diseases, Poznan University of Medical Sciences, Poland.

Objectives: To evaluate the role of MTHFR genetic variants in the etiology of intrauterine fetal death in the second part of pregnancy at women from Polish population.

Material And Methods: A case-control study was performed on a 76 women with a positive history of at least one in- trauterine fetal death after 22 gestational week and 400 healthy controls. The MTHFR genotyping for polymorphic sites 667C > T, 1298A > C, 1793G > A was determined by polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP) method. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.2019.0013DOI Listing
January 2019
6 Reads

Influence of human Papilloma Virus (hPV) infection on early pregnancy.

Ginekol Pol 2019 ;90(2):72-75

Medical University of Lodz, Poland.

Objectives: HPV infection in early pregnancy may be a cause of miscarriage. Pregnancy significantly increases the risk of HPV infection. While ascending intrauterine infection with colonization of the trophoblast is commonly observed, descend- ing hematogenous infection should also be considered. Read More

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http://dx.doi.org/10.5603/GP.2019.0012DOI Listing
January 2019

Sensitivity and specificity of HR HPV E6/E7 mRNA test in detecting cervical squamous intraepithelial lesion and cervical cancer

Ginekol Pol 2019 ;90(2):66-71

Division of Gynecology, Department of Perinatology and Gynecology, Gynecology and Obstetrics Clinical Hospital, Karol Marcinkowski University of Medical Sciences, Poznan, Poland.

Objectives: The paper assess the relevance of HR HPV E6/E7 mRNA test in women with abnormal Pap results.

Material And Methods: Between 2013-2014, 125 women were subjects to the enhanced diagnostics due to abnormal Pap results. According to The Bethesda system, if ASC-US, AGC, LSIL, ASC-H, HSIL or cancer cells were present, the result was abnormal. Read More

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http://dx.doi.org/10.5603/GP.2019.0011DOI Listing
January 2019
1 Read

Hormonal contraception in patients with epilepsy.

Ginekol Pol 2019 ;90(2):61-65

Collegium Medicum, Jagiellonian University of Cracow, Poland.

Objectives: The aim of the study was to evaluate hormonal contraception use in women with epilepsy and to assess the risk of potential interactions between contraceptives and antiepileptic drugs (AEDs).

Material And Methods: Data on hormonal contraception were obtained prospectively in women of childbearing age treated in the university epilepsy clinic.

Results: We evaluated 334 women with epilepsy (mean age 30. Read More

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http://dx.doi.org/10.5603/GP.2019.0010DOI Listing
January 2019
4 Reads

Is there a future for cell-free fetal dna tests in screening for preeclampsia?

Ginekol Pol 2019 ;90(1):55-60

First Department of Obstetrics and Gynaecology, Medical University of Warsaw, Poland.

CffDNA screening is a powerful diagnostic tool in the prenatal diagnosis algorithm for chromosomal abnormalities. With detailed ultrasound examination as the mainstay of first-trimester risk assessment, cffDNA has been shown to be superior to first-trimester combined screening (FTCS) in false-positive rates for trisomy 21 detection. In light of the growing interest in cffDNA testing and the possibility of it replacing first-trimester biochemistry, we decided to investigate the usefulness of cffDNA tests in early-pregnancy risk assessment for preeclampsia (PE). Read More

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http://dx.doi.org/10.5603/GP.2019.0009DOI Listing
January 2019
8 Reads

The relationship between pre-pregnancy BMI, gestational weight gain and neonatal birth weight: a retrospective cohort study.

Ginekol Pol 2019 ;90(1):50-54

Jagiellonian University Collegium Medicum, Department of Obstetrics and Perinatology, Cracow, Poland.

Objectives: Maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) have a meaningful impact on pregnancy and perinatal outcomes. The first aim of the study was to analyze the association between pre-pregnancy BMI and the prevalence of small for gestational age (SGA) and large for gestational age (LGA) outcomes. The second aim was to assess the relation- ship between pre-pregnancy BMI combined with gestational weight gain (GWG) and the prevalence of SGA and LGA measurements. Read More

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http://dx.doi.org/10.5603/GP.2019.0008DOI Listing
January 2019
2 Reads

Effects of nutritional nursing intervention based on glycemic load for patient with gestational diabetes mellitus.

Ginekol Pol 2019 ;90(1):46-49

Department of Gynecology and Obstetrics, Yantai Hospital of Traditional Chinese Medicine, Yantai City, China.

Objectives: To determine the effects of nutritional nursing intervention based on glycemic load (GL) for patients with gestational diabetes mellitus.

Material And Methods: One hundred thirty-four patients diagnosed with gestational diabetes mellitus at our hospital were selected from March 2015 to March 2017 and randomly divided into the observation (n = 67) and control groups (n = 67). All of the patients in the observation and control groups received conventional nutritional nursing. Read More

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http://dx.doi.org/10.5603/GP.2019.0007DOI Listing
January 2019
4 Reads

Decreased Filamin b expression regulates trophoblastic cells invasion through ERK/MMP-9 pathway in pre-eclampsia.

Ginekol Pol 2019 ;90(1):39-45

Department of Obstetrics, Affiliated Hospital of Qingdao University, China.

Objectives: The purpose of this study was to investigate the expression of Filamin b in the placental placenta of patients with early or late onset pre-eclampsia (PE) and its potential effects on the pathophysiology of the disease.

Methods And Methods: Immunohistochemistry staining, western blot assays and real time PCR were used to detect the expression level of FLN-b. The expression levels of MMP-2, MMP-9 and ERK1/2 proteins from control and FLN-b-silenced JEG-3 cells were also detected by western blot and JEG-3 cell invasion. Read More

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http://dx.doi.org/10.5603/GP.2019.0006DOI Listing
January 2019
2 Reads

Prenatally diagnosed foramen ovale restriction in fetuses with hypoplastic left heart syndrome may be a predictor of longer hospitalization, but not of a need for an urgent rashkind procedure.

Ginekol Pol 2019 ;90(1):31-38

Department of Prenatal Cardiology in Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.

Objectives: This prospective study aimed to assess the effectiveness of foramen ovale examination in classifying prenatal hypoplastic left heart syndrome (HLHS) in accordance with the new classification groupings for congenital heart defects.

Material And Methods: The analysis included 145 fetuses with HLHS, diagnosed and monitored between 2008 and 2015 in Prenatal Cardiology Department at Polish Mother's Memorial Hospital Research Institute in Lodz. The main criteria for classifying our study population into three sub-groups was was the presence of a foramen ovale restriction, which we diagnosed by evaluating the diameter and blood flow through the foramen ovale. Read More

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http://dx.doi.org/10.5603/GP.2019.0005DOI Listing
January 2019
2 Reads

The impact of low volume lymph node metastases and stage migration after pathologic ultrastaging of non-sentinel lymph nodes in early-stage cervical cancer: a study of 54 patients with 4.2 years of follow up.

Ginekol Pol 2019 ;90(1):20-30

Department of Gynecology, Gynecologic Oncology and Gynecologic Endocrinology, Medical University of Gdansk, Poland.

Objectives: To assess the significance of pathologic ultrastaging (PU) of sentinel (SLN) and non-sentinel (nSLN) lymph nodes (LNs) and the influence on cancer staging in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IA2-IB1 cervical cancer.

Material And Methods: A retrospective study was conducted with 54 patients divided into two equal-sized groups. In test group (n1), at least one SLN/patient was detected with blue dye. Read More

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http://dx.doi.org/10.5603/GP.2019.0004DOI Listing
January 2019
5 Reads

High tumor cell vimentin expression indicates prolonged survival in patients with ovarian malignant tumors.

Ginekol Pol 2019 ;90(1):11-19

Department of Tumour Pathology and Pathomorphology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland.

Objectives: The main aims of the study were to investigate the expression of vimentin and its correlation with the overall survival (OS) of patients with malignant ovarian tumors, and the correlation between vimentin expression and tumor stroma characteristics.

Material And Methods: The study focused on 94 malignant ovarian tumors that had been collected from women who were treated in the Department of Gynecology and Oncology of the Lukaszczyk Oncological Center, Bydgoszcz, Poland. Vimentin expression was assessed in both the cancer cells (expression intensity and quantitative analysis) and the tumor stroma (expression intensity). Read More

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http://dx.doi.org/10.5603/GP.2019.0003DOI Listing
January 2019
4 Reads

Metabolic and hormonal effects of a combined Myo-inositol and d-chiro-inositol therapy on patients with polycystic ovary syndrome (PCOS).

Ginekol Pol 2019 ;90(1):7-10

Department of Obstetrics and Gynecology, Central Clinical Hospital of Interior, Warsaw, Poland.

Objectives: To evaluate the effects of a combined Myo-inositol (MI) and D-chiro-inositol (DCI) therapy on the hormonal and metabolic parameters of women with PCOS. Prospective clinical study. Clinical Study registration number - EUPAS25705 Material and methods: Seventy women diagnosed with PCOS according to the Rotterdam criteria were enrolled in this study. Read More

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http://dx.doi.org/10.5603/GP.2019.0002DOI Listing
January 2019
9 Reads

Peroxiredoxin-5 is a negative survival predictor in ovarian cancer.

Ginekol Pol 2019 ;90(1):1-6

Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Poland.

Objectives: Peroxiredoxins (PRDXs) constitute a family of antioxidant enzymes which are also involved in the process of carcinogenesis. They are composed of six identified isoforms (PRDX-1-6) and are supposed to play different roles in tumor progression, depending on type of cancer and member of the PRDX family. The aim of the study was to assess the prog- nostic value of PRDXs in ovarian cancer. Read More

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http://dx.doi.org/10.5603/GP.2019.0001DOI Listing
January 2019
1 Read

Perinatal and cardiovascular outcomes in a pregnant patient with Marfan syndrome.

Ginekol Pol 2018 ;89(12):716-717

Poznan University of Medical Sciences Division of Reproduction, Poland.

A 25-year-old primigravida with Marfan syndrome (MFS) was admitted at 36 weeks of gestation (WOG). Read More

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http://dx.doi.org/10.5603/GP.a2018.0121DOI Listing
January 2018
2 Reads

Current treatment options for advanced choriocarcinoma on the basis of own case and review of the literature.

Ginekol Pol 2018 ;89(12):711-715

The Chair and Clinic of Obstetrics, Gynaecologic Diseases and Oncological Gynaecology of the Second Faculty of Medicine of Warsaw Medical University, Poland.

Choriocarcinoma is one of rare neoplasms of female reproductive organs. In the last decade only a few cases of this disease have been registered in Poland. The paper presents the current principles of diagnosis and treatment options for this rare disease based on the authors' clinical experience (description of the case) and literature review. Read More

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http://dx.doi.org/10.5603/GP.a2018.0120DOI Listing
January 2018
3 Reads

An observational study of the risk of neonatal macrosomia, and early gestational diabetes associated with selected candidate genes for type 2 diabetes mellitus polymorphisms in women with gestational diabetes mellitus.

Ginekol Pol 2018 ;89(12):705-710

Department of Reproduction, Karol Marcinkowski University of Medical Sciences, Poznan, Poland.

Objectives: 1) to analyse the prevalence of selected candidate genes for type 2 diabetes mellitus polymorphisms (IRS1 G972R; ENPP1 K121Q; ADRB3 W64R) among women with gestational diabetes; and 2) to investigate any association between variants of these genes and risk of neonatal macrosomia.

Material And Methods: We conducted a prospective observational study of a group of women (N = 140) in singleton pregnancies who delivered at term. Characteristics of the study group at enrolment: age: 32. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0119DOI Listing
January 2018
12 Reads

An investigation of the effect of placental growth factor on intrapartum fetal compromise prediction in terminduced high risk pregnancies.

Ginekol Pol 2018 ;89(12):700-704

Department of Obstetrics and Gynecology, Health Sciences University Diyarbakır Gazi Yaşargil Education and Research Hospital, Diyarbakır, Turkey.

Objectives: To date, there is no available test to predict the risk of intrapartum fetal compromise (IFC) during labor, either starting spontaneously or induced due to obstetrics indications. The aim of this study was to examine the effectiveness of placental growth factor (PIGF) in identifying cases that develop intrapartum fetal compromise (IFC) in term high-risk pregnancies induced for labor.

Material And Methods: This prospective cross-sectional study was conducted on 40 IFC+ cases and 40 IFC- cases with high-risk term pregnancy and labor induction started in the Health Sciences University Gazi Yaşargil Training and Research Hospital, between January 2018 and April 2018. Read More

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http://dx.doi.org/10.5603/GP.a2018.0118DOI Listing
January 2018
3 Reads

Pregnancy and the eye. Changes in morphology of the cornea and the anterior chamber of the eye in pregnant woman.

Ginekol Pol 2018 ;89(12):695-699

Chair and Department of Ophthalmology, 1st Faculty of Medicine, Medical University of Warsaw, Poland.

Objectives: The main goal of the study was to determine whether uncomplicated pregnancy and natural labor exert influence on the cornea and the anterior chamber of the eye.

Material And Methods: The study included 114 eyes of 57 women in age of 21-35 years old. Only patients in the physiological pregnancy and giving natural birth were recruited into study. Read More

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http://dx.doi.org/10.5603/GP.a2018.0117DOI Listing
January 2018
3 Reads

Proteomic pattern of cervico-vaginal fluid (CVF) in an ovarian cancer diagnosis - pilot study.

Ginekol Pol 2018 ;89(12):688-694

Department of Gynecology, Obstetrics and Gynecologic Oncology, Division of Gynecologic Oncology, Poznan University of Medical Sciences, Poznan, Polska.

Objectives: High grade serous ovarian cancer (HGSC) is the most common type of ovarian cancer and is responsible for about 90% of ovarian cancer deaths. The diagnostic tests currently used do not increase the detection rates for ovarian cancer. There is a great necessity to develop new and non-invasive diagnostic tests for ovarian cancer (OC). Read More

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http://dx.doi.org/10.5603/GP.a2018.0116DOI Listing
January 2018
5 Reads

Diagnostic and prognostic relevance of microparticles in peripheral and uterine blood of patients with endometrial cancer.

Ginekol Pol 2018 ;89(12):682-687

Department of Gynecology and Oncology, University Hospital, Cracow, Poland.

Objectives: Exosomes - microvesicles which are secreted by living cells - can be produced from different cell types and detected in various body fluids. They are the carriers of intercellular information which regulate tumor microenvironment and are considered to be involved in tumor progression and metastasis. Cancer cells can secrete more exosomes than healthy cells, and are expected to be potential tools for tumor diagnosis and treatment. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0115DOI Listing
January 2018
13 Reads

Telemedicine consultations in obstetrics and gynecology - a population based study in Polishspeaking women.

Ginekol Pol 2018 ;89(12):677-681

Telemedicine Clinic, eDoktor24, Warsaw, Poland.

Objectives: Telemedicine is no longer in the realm of the future. It has already become an aspect of modern medicine. A number of countries across the world have successfully introduced telemedicine systems, which allows patients access to general healthcare and specialist consultations regardless of the distance separating patients from physicians. Read More

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http://dx.doi.org/10.5603/GP.a2018.0114DOI Listing
January 2018
2 Reads

Hysterectomy costs depending on operational technique.

Ginekol Pol 2018 ;89(12):672-676

Department of Obstetrics and Gynecology with Gynecological Oncology Subdivision, Brothers Hospitallers of Saint John of God Hospital, Katowice, Poland.

Objectives: The aim of the study was to perform a comparative analysis of hysterectomy costs versus the operative technique based on the data of 656 patients operated at the Department of Obstetrics and Gynecology with Gynecological Oncology Subdivision, Brothers Hospitallers of Saint John of God Hospital, Katowice, between 2016 and 2018 (until May 31, 2018).

Material And Methods: This retrospective research involved 656 patients who underwent hysterectomy for non-oncological reasons. The patients were subdivided into three groups, depending on the operative method (transabdominal, laparoscopic or transvaginal). Read More

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http://dx.doi.org/10.5603/GP.a2018.0113DOI Listing
January 2018
3 Reads

Stage IB1 cervical cancer treated with modified radical or radical hysterectomy: does size determine risk factors?

Ginekol Pol 2018 ;89(12):667-671

Mersin State Hospital, Department of Obstetrics and Gynecology, Mersin, Turkey.

Objectives: This study was performed to investigate prognostic factors status at smaller tumors in patients with stageIB1 cervical cancer (CC) who underwent modified radical or radical hysterectomy.

Matherial And Metods: Data from patients diagnosed with CC between January 1995 and January 2017 at the GynecologicalOncology Department, Tepecik Training and Research Hospital and Bakirkoy Dr. Sadi Konuk Training and Research Hospital,Istanbul, Turkey, were investigated. Read More

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http://dx.doi.org/10.5603/GP.a2018.0112DOI Listing
January 2018
4 Reads

Dietary macronutrients and fluid intakes in a sample of pregnant women with either gestational diabetes or type 1 diabetes mellitus, assessed in comparison with Polish nutritional guidelines.

Ginekol Pol 2018 ;89(12):659-666

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: Pregnancy is a critical period during which environmental factors such as nutrition can affect development. Maintaining proper nutrition becomes even more significant when pregnant women have diabetes. The aim of this study was to measure changes in energy and macronutrient intakes among pregnant women and patients diagnosed either with gestational diabetes mellitus (GDM) during pregnancy, or, type 1 diabetes mellitus (T1DM) before pregnancy, and to assess the pregnant women's dietary intakes in comparison with Polish Institute of Food and Nutrition nutritional guidelines. Read More

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http://dx.doi.org/10.5603/GP.a2018.0111DOI Listing
January 2018
3 Reads

Spontaneous umbilical cord hematoma as a clinical and forensic medical problem in case of suspected obstetrician's medical malpractice.

Ginekol Pol 2018;89(11):642-643

Department of Forensic Medicine and Forensic Toxicology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Poland.

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http://dx.doi.org/10.5603/GP.a2018.0109DOI Listing
February 2019
2 Reads

Contemporary management of prenatally diagnosed spina bifida aperta - an update.

Ginekol Pol 2018;89(11):637-641

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Spina bifida aperta is a relatively common congenital defect that occurs in the general population. Once the disorder has been diagnosed, a discussion, that can be emotionally-charged, ensues about whether to treat it prenatally or to only offer surgery postnatally. Given that there are good arguments for and against both options, it is of paramount importance to gain a good understanding of the major advantages and disadvantages of the various surgical approaches. Read More

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http://dx.doi.org/10.5603/GP.a2018.0108DOI Listing
February 2019
5 Reads

An exploratory study of the effect of labor pain management on postpartum depression among Chinese women.

Ginekol Pol 2018;89(11):627-636

Department of Nursing, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Department of Nursing, Haining Maternal and Child Health Care Hospital, Haining, China.

Objectives: The purpose of this study was to investigate the effects of pain relief during labor on the occurrence of potential postpartum depression in early postpartum among Chinese women.

Material And Methods: A quasi-experimental study used, with a convenience sample of 565 women who delivered at the Women's Hospital, School of Medicine. Three types of pain relief were administered based on the women's preference (doula, n = 301; transcutaneous electrical nerve stimulation, n = 51; epidural analgesia, n = 213). Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0107DOI Listing
February 2019
16 Reads