9,211 results match your criteria Ginekologia polska[Journal]


Is there a future for cell-free fetal dna tests in screening for preeclampsia?

Ginekol Pol 2019 ;90(1):55-60

First Department of Obstetrics and Gynaecology, Medical University of Warsaw, Poland.

CffDNA screening is a powerful diagnostic tool in the prenatal diagnosis algorithm for chromosomal abnormalities. With detailed ultrasound examination as the mainstay of first-trimester risk assessment, cffDNA has been shown to be superior to first-trimester combined screening (FTCS) in false-positive rates for trisomy 21 detection. In light of the growing interest in cffDNA testing and the possibility of it replacing first-trimester biochemistry, we decided to investigate the usefulness of cffDNA tests in early-pregnancy risk assessment for preeclampsia (PE). Read More

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http://dx.doi.org/10.5603/GP.2019.0009DOI Listing
January 2019
1 Read

The relationship between pre-pregnancy BMI, gestational weight gain and neonatal birth weight: a retrospective cohort study.

Ginekol Pol 2019 ;90(1):50-54

Jagiellonian University Collegium Medicum, Department of Obstetrics and Perinatology, Cracow, Poland.

Objectives: Maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) have a meaningful impact on pregnancy and perinatal outcomes. The first aim of the study was to analyze the association between pre-pregnancy BMI and the prevalence of small for gestational age (SGA) and large for gestational age (LGA) outcomes. The second aim was to assess the relation- ship between pre-pregnancy BMI combined with gestational weight gain (GWG) and the prevalence of SGA and LGA measurements. Read More

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http://dx.doi.org/10.5603/GP.2019.0008DOI Listing
January 2019
1 Read

Effects of nutritional nursing intervention based on glycemic load for patient with gestational diabetes mellitus.

Ginekol Pol 2019 ;90(1):46-49

Department of Gynecology and Obstetrics, Yantai Hospital of Traditional Chinese Medicine, Yantai City, China.

Objectives: To determine the effects of nutritional nursing intervention based on glycemic load (GL) for patients with gestational diabetes mellitus.

Material And Methods: One hundred thirty-four patients diagnosed with gestational diabetes mellitus at our hospital were selected from March 2015 to March 2017 and randomly divided into the observation (n = 67) and control groups (n = 67). All of the patients in the observation and control groups received conventional nutritional nursing. Read More

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http://dx.doi.org/10.5603/GP.2019.0007DOI Listing
January 2019

Decreased Filamin b expression regulates trophoblastic cells invasion through ERK/MMP-9 pathway in pre-eclampsia.

Ginekol Pol 2019 ;90(1):39-45

Department of Obstetrics, Affiliated Hospital of Qingdao University, China.

Objectives: The purpose of this study was to investigate the expression of Filamin b in the placental placenta of patients with early or late onset pre-eclampsia (PE) and its potential effects on the pathophysiology of the disease.

Methods And Methods: Immunohistochemistry staining, western blot assays and real time PCR were used to detect the expression level of FLN-b. The expression levels of MMP-2, MMP-9 and ERK1/2 proteins from control and FLN-b-silenced JEG-3 cells were also detected by western blot and JEG-3 cell invasion. Read More

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http://dx.doi.org/10.5603/GP.2019.0006DOI Listing
January 2019

Prenatally diagnosed foramen ovale restriction in fetuses with hypoplastic left heart syndrome may be a predictor of longer hospitalization, but not of a need for an urgent rashkind procedure.

Ginekol Pol 2019 ;90(1):31-38

Department of Prenatal Cardiology in Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.

Objectives: This prospective study aimed to assess the effectiveness of foramen ovale examination in classifying prenatal hypoplastic left heart syndrome (HLHS) in accordance with the new classification groupings for congenital heart defects.

Material And Methods: The analysis included 145 fetuses with HLHS, diagnosed and monitored between 2008 and 2015 in Prenatal Cardiology Department at Polish Mother's Memorial Hospital Research Institute in Lodz. The main criteria for classifying our study population into three sub-groups was was the presence of a foramen ovale restriction, which we diagnosed by evaluating the diameter and blood flow through the foramen ovale. Read More

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http://dx.doi.org/10.5603/GP.2019.0005DOI Listing
January 2019
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The impact of low volume lymph node metastases and stage migration after pathologic ultrastaging of non-sentinel lymph nodes in early-stage cervical cancer: a study of 54 patients with 4.2 years of follow up.

Ginekol Pol 2019 ;90(1):20-30

Department of Gynecology, Gynecologic Oncology and Gynecologic Endocrinology, Medical University of Gdansk, Poland.

Objectives: To assess the significance of pathologic ultrastaging (PU) of sentinel (SLN) and non-sentinel (nSLN) lymph nodes (LNs) and the influence on cancer staging in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IA2-IB1 cervical cancer.

Material And Methods: A retrospective study was conducted with 54 patients divided into two equal-sized groups. In test group (n1), at least one SLN/patient was detected with blue dye. Read More

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http://dx.doi.org/10.5603/GP.2019.0004DOI Listing
January 2019

High tumor cell vimentin expression indicatesprolonged survival in patients with ovarian malignant tumors.

Ginekol Pol 2019 ;90(1):11-19

Department of Tumour Pathology and Pathomorphology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland.

Objectives: The main aims of the study were to investigate the expression of vimentin and its correlation with the overall survival (OS) of patients with malignant ovarian tumors, and the correlation between vimentin expression and tumor stroma characteristics.

Material And Methods: The study focused on 94 malignant ovarian tumors that had been collected from women who were treated in the Department of Gynecology and Oncology of the Lukaszczyk Oncological Center, Bydgoszcz, Poland. Vimentin expression was assessed in both the cancer cells (expression intensity and quantitative analysis) and the tumor stroma (expression intensity). Read More

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http://dx.doi.org/10.5603/GP.2019.0003DOI Listing
January 2019
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Metabolic and hormonal effects of a combined Myo-inositol and d-chiro-inositol therapy on patients with polycystic ovary syndrome (PCOS).

Ginekol Pol 2019 ;90(1):7-10

Department of Obstetrics and Gynecology, Central Clinical Hospital of Interior, Warsaw, Poland.

Objectives: To evaluate the effects of a combined Myo-inositol (MI) and D-chiro-inositol (DCI) therapy on the hormonal and metabolic parameters of women with PCOS. Prospective clinical study. Clinical Study registration number - EUPAS25705 Material and methods: Seventy women diagnosed with PCOS according to the Rotterdam criteria were enrolled in this study. Read More

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http://dx.doi.org/10.5603/GP.2019.0002DOI Listing
January 2019
5 Reads

Peroxiredoxin-5 is a negative survival predictor in ovarian cancer.

Ginekol Pol 2019 ;90(1):1-6

Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Poland.

Objectives: Peroxiredoxins (PRDXs) constitute a family of antioxidant enzymes which are also involved in the process of carcinogenesis. They are composed of six identified isoforms (PRDX-1-6) and are supposed to play different roles in tumor progression, depending on type of cancer and member of the PRDX family. The aim of the study was to assess the prog- nostic value of PRDXs in ovarian cancer. Read More

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http://dx.doi.org/10.5603/GP.2019.0001DOI Listing
January 2019

Perinatal and cardiovascular outcomes in a pregnant patient with Marfan syndrome.

Ginekol Pol 2018 ;89(12):716-717

Poznan University of Medical Sciences Division of Reproduction, Poland.

A 25-year-old primigravida with Marfan syndrome (MFS) was admitted at 36 weeks of gestation (WOG). Read More

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http://dx.doi.org/10.5603/GP.a2018.0121DOI Listing
January 2018
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Current treatment options for advanced choriocarcinoma on the basis of own case and review of the literature.

Ginekol Pol 2018 ;89(12):711-715

The Chair and Clinic of Obstetrics, Gynaecologic Diseases and Oncological Gynaecology of the Second Faculty of Medicine of Warsaw Medical University, Poland.

Choriocarcinoma is one of rare neoplasms of female reproductive organs. In the last decade only a few cases of this disease have been registered in Poland. The paper presents the current principles of diagnosis and treatment options for this rare disease based on the authors' clinical experience (description of the case) and literature review. Read More

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http://dx.doi.org/10.5603/GP.a2018.0120DOI Listing
January 2018
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An observational study of the risk of neonatal macrosomia, and early gestational diabetes associated with selected candidate genes for type 2 diabetes mellitus polymorphisms in women with gestational diabetes mellitus.

Ginekol Pol 2018 ;89(12):705-710

Department of Reproduction, Karol Marcinkowski University of Medical Sciences, Poznan, Poland.

Objectives: 1) to analyse the prevalence of selected candidate genes for type 2 diabetes mellitus polymorphisms (IRS1 G972R; ENPP1 K121Q; ADRB3 W64R) among women with gestational diabetes; and 2) to investigate any association between variants of these genes and risk of neonatal macrosomia.

Material And Methods: We conducted a prospective observational study of a group of women (N = 140) in singleton pregnancies who delivered at term. Characteristics of the study group at enrolment: age: 32. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0119DOI Listing
January 2018
5 Reads

An investigation of the effect of placental growth factor on intrapartum fetal compromise prediction in terminduced high risk pregnancies.

Ginekol Pol 2018 ;89(12):700-704

Department of Obstetrics and Gynecology, Health Sciences University Diyarbakır Gazi Yaşargil Education and Research Hospital, Diyarbakır, Turkey.

Objectives: To date, there is no available test to predict the risk of intrapartum fetal compromise (IFC) during labor, either starting spontaneously or induced due to obstetrics indications. The aim of this study was to examine the effectiveness of placental growth factor (PIGF) in identifying cases that develop intrapartum fetal compromise (IFC) in term high-risk pregnancies induced for labor.

Material And Methods: This prospective cross-sectional study was conducted on 40 IFC+ cases and 40 IFC- cases with high-risk term pregnancy and labor induction started in the Health Sciences University Gazi Yaşargil Training and Research Hospital, between January 2018 and April 2018. Read More

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http://dx.doi.org/10.5603/GP.a2018.0118DOI Listing
January 2018
2 Reads

Pregnancy and the eye. Changes in morphology of the cornea and the anterior chamber of the eye in pregnant woman.

Ginekol Pol 2018 ;89(12):695-699

Chair and Department of Ophthalmology, 1st Faculty of Medicine, Medical University of Warsaw, Poland.

Objectives: The main goal of the study was to determine whether uncomplicated pregnancy and natural labor exert influence on the cornea and the anterior chamber of the eye.

Material And Methods: The study included 114 eyes of 57 women in age of 21-35 years old. Only patients in the physiological pregnancy and giving natural birth were recruited into study. Read More

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http://dx.doi.org/10.5603/GP.a2018.0117DOI Listing
January 2018
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Proteomic pattern of cervico-vaginal fluid (CVF) in an ovarian cancer diagnosis - pilot study.

Ginekol Pol 2018 ;89(12):688-694

Department of Gynecology, Obstetrics and Gynecologic Oncology, Division of Gynecologic Oncology, Poznan University of Medical Sciences, Poznan, Polska.

Objectives: High grade serous ovarian cancer (HGSC) is the most common type of ovarian cancer and is responsible for about 90% of ovarian cancer deaths. The diagnostic tests currently used do not increase the detection rates for ovarian cancer. There is a great necessity to develop new and non-invasive diagnostic tests for ovarian cancer (OC). Read More

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http://dx.doi.org/10.5603/GP.a2018.0116DOI Listing
January 2018
3 Reads

Diagnostic and prognostic relevance of microparticles in peripheral and uterine blood of patients with endometrial cancer.

Ginekol Pol 2018 ;89(12):682-687

Department of Gynecology and Oncology, University Hospital, Cracow, Poland.

Objectives: Exosomes - microvesicles which are secreted by living cells - can be produced from different cell types and detected in various body fluids. They are the carriers of intercellular information which regulate tumor microenvironment and are considered to be involved in tumor progression and metastasis. Cancer cells can secrete more exosomes than healthy cells, and are expected to be potential tools for tumor diagnosis and treatment. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0115DOI Listing
January 2018
6 Reads

Telemedicine consultations in obstetrics and gynecology - a population based study in Polishspeaking women.

Ginekol Pol 2018 ;89(12):677-681

Telemedicine Clinic, eDoktor24, Warsaw, Poland.

Objectives: Telemedicine is no longer in the realm of the future. It has already become an aspect of modern medicine. A number of countries across the world have successfully introduced telemedicine systems, which allows patients access to general healthcare and specialist consultations regardless of the distance separating patients from physicians. Read More

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http://dx.doi.org/10.5603/GP.a2018.0114DOI Listing
January 2018
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Hysterectomy costs depending on operational technique.

Ginekol Pol 2018 ;89(12):672-676

Department of Obstetrics and Gynecology with Gynecological Oncology Subdivision, Brothers Hospitallers of Saint John of God Hospital, Katowice, Poland.

Objectives: The aim of the study was to perform a comparative analysis of hysterectomy costs versus the operative technique based on the data of 656 patients operated at the Department of Obstetrics and Gynecology with Gynecological Oncology Subdivision, Brothers Hospitallers of Saint John of God Hospital, Katowice, between 2016 and 2018 (until May 31, 2018).

Material And Methods: This retrospective research involved 656 patients who underwent hysterectomy for non-oncological reasons. The patients were subdivided into three groups, depending on the operative method (transabdominal, laparoscopic or transvaginal). Read More

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http://dx.doi.org/10.5603/GP.a2018.0113DOI Listing
January 2018
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Stage IB1 cervical cancer treated with modified radical or radical hysterectomy: does size determine risk factors?

Ginekol Pol 2018 ;89(12):667-671

Mersin State Hospital, Department of Obstetrics and Gynecology, Mersin, Turkey.

Objectives: This study was performed to investigate prognostic factors status at smaller tumors in patients with stageIB1 cervical cancer (CC) who underwent modified radical or radical hysterectomy.

Matherial And Metods: Data from patients diagnosed with CC between January 1995 and January 2017 at the GynecologicalOncology Department, Tepecik Training and Research Hospital and Bakirkoy Dr. Sadi Konuk Training and Research Hospital,Istanbul, Turkey, were investigated. Read More

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http://dx.doi.org/10.5603/GP.a2018.0112DOI Listing
January 2018
2 Reads

Dietary macronutrients and fluid intakes in a sample of pregnant women with either gestational diabetes or type 1 diabetes mellitus, assessed in comparison with Polish nutritional guidelines.

Ginekol Pol 2018 ;89(12):659-666

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Objectives: Pregnancy is a critical period during which environmental factors such as nutrition can affect development. Maintaining proper nutrition becomes even more significant when pregnant women have diabetes. The aim of this study was to measure changes in energy and macronutrient intakes among pregnant women and patients diagnosed either with gestational diabetes mellitus (GDM) during pregnancy, or, type 1 diabetes mellitus (T1DM) before pregnancy, and to assess the pregnant women's dietary intakes in comparison with Polish Institute of Food and Nutrition nutritional guidelines. Read More

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http://dx.doi.org/10.5603/GP.a2018.0111DOI Listing
January 2018
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Spontaneous umbilical cord hematoma as a clinical and forensic medical problem in case of suspected obstetrician's medical malpractice.

Ginekol Pol 2018;89(11):642-643

Department of Forensic Medicine and Forensic Toxicology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Poland.

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http://dx.doi.org/10.5603/GP.a2018.0109DOI Listing
January 2018
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Contemporary management of prenatally diagnosed spina bifida aperta - an update.

Ginekol Pol 2018;89(11):637-641

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland.

Spina bifida aperta is a relatively common congenital defect that occurs in the general population. Once the disorder has been diagnosed, a discussion, that can be emotionally-charged, ensues about whether to treat it prenatally or to only offer surgery postnatally. Given that there are good arguments for and against both options, it is of paramount importance to gain a good understanding of the major advantages and disadvantages of the various surgical approaches. Read More

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http://dx.doi.org/10.5603/GP.a2018.0108DOI Listing
January 2018
3 Reads

An exploratory study of the effect of labor pain management on postpartum depression among Chinese women.

Ginekol Pol 2018;89(11):627-636

Department of Nursing, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Department of Nursing, Haining Maternal and Child Health Care Hospital, Haining, China.

Objectives: The purpose of this study was to investigate the effects of pain relief during labor on the occurrence of potential postpartum depression in early postpartum among Chinese women.

Material And Methods: A quasi-experimental study used, with a convenience sample of 565 women who delivered at the Women's Hospital, School of Medicine. Three types of pain relief were administered based on the women's preference (doula, n = 301; transcutaneous electrical nerve stimulation, n = 51; epidural analgesia, n = 213). Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0107DOI Listing
January 2018
8 Reads

An analysis of the influence of infection on overall survival rates, following modified posterior pelvic exenteration for advanced ovarian cancer.

Ginekol Pol 2018;89(11):618-626

Clinical Department of Gynecological Oncology, Professor Franciszek Lukaszczyk Oncology Center, Bydgoszcz, Poland; Department of Oncology, Radiotherapy and Oncological Gynecology, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.

Objectives The aim of our study has been to determine the association between the appearance of infection after modified posterior pelvic exenteration (MPE) and TTC (time to adjuvant chemotherapy) and to examine whether the infection impacts clinical results by delaying the start of chemotherapy. Material and methods The present, retrospective study analyzed 77 patients who had undergone MPE followed by adjuvant chemotherapy. Either no residual tumor or tumor less than 2. Read More

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http://dx.doi.org/10.5603/GP.a2018.0106DOI Listing
January 2018
1 Read

Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy.

Ginekol Pol 2018;89(11):611-617

Department of Obstetrics and Gynecology, Pusan National University School of Medicine Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Objectives: The purpose of this study was to identify clinical risk factors for the recurrence of ovarian endometrioma after ovarian cystectomy in Korean women with long-term postoperative medical therapy.

Material And Methods: A total of 134 patients who were surgically treated for endometriotic cysts at Pusan National University Hospital were included in this retrospective study. All patients received long-term postoperative medical treatment for at least 12 months after the first-line conservative surgery. Read More

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http://dx.doi.org/10.5603/GP.a2018.0105DOI Listing
January 2018
2 Reads

Aromatase inhibitor therapy for endometrial stromal sarcoma - two-centre experience.

Ginekol Pol 2018;89(11):607-610

Department of Oncology and Radiotherapy, Medical University of Gdansk, Poland.

Objectives: Endocrine therapy is the recommended systemic treatment for steroid receptor positive endometrial stromal sarcoma (ESS). There is no current consensus on the optimal hormonal therapy for ESS. The literature offers several reports on advanced/recurrent/metastatic ESS patients treated with progestins, whereas data on the efficacy of aromatase inhibitors are scarce. Read More

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http://dx.doi.org/10.5603/GP.a2018.0104DOI Listing
January 2018
3 Reads

The preoperative serum CA125 can predict the lymph node metastasis in endometrioid-type endometrial cancer.

Ginekol Pol 2018;89(11):599-606

Etlik Zubeyde Hanim Women's Health Training and Research Hospital, Faculty of Medicine, University of Health Sciences, Department of Gynecology, Ankara, Turkey.

Objectives: To evaluate the predictive value of preoperative CA125 in extra-uterine disease and its association with poor prognostic factors in endometrioid-type endometrial cancer (EC).

Material And Methods: A total of 423 patients with pathologically proven endometrioid-type EC were included in the study. The association between preoperative CA125 level and surgical-pathological factors was evaluated. Read More

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http://dx.doi.org/10.5603/GP.a2018.0103DOI Listing
January 2018
2 Reads

Isolated pulmonary metastases in patients with cervical cancer and the factors affecting survival after recurrence.

Ginekol Pol 2018;89(11):593-598

Mersin State Hospital, Department of Obstetrics and Gynecology, Mersin, Turkey.

Objectives: The aim of this study was to assess the treatment options and survival of uterine cervical cancer (UCC) patients who develop isolated pulmonary metastases (IPM) and to establish risk factors for IPM.

Material And Methods: Data from patients diagnosed with UCC between June 1991 and January 2017 at the Gynecological Oncology Department, Tepecik Training and Research Hospital, were investigated. In total, 43 cases with IPM were evaluated retrospectively. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0102DOI Listing
January 2018
13 Reads

Cognitive changes in older women after urogynaecological surgery.

Ginekol Pol 2018;89(11):587-592

Frauenzimmer Bern AG, Bern, Switzerland.

Objectives: The need for pelvic floor surgery will increase with an aging population in the future. Aim of this prospective study was to evaluate the evolution of cognitive function in elderly women after urogynaecological surgery.

Material And Methods: Between 2010 and 2014, 51 female patients 70 years and older who underwent urogynaecological surgery participated in this study. Read More

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http://dx.doi.org/10.5603/GP.a2018.0101DOI Listing
January 2018
3 Reads

Dietary vitamin and mineral intakes in a sample of pregnant women with either gestational diabetes or type 1 diabetes mellitus, assessed in comparison with Polish nutritional guidelines.

Ginekol Pol 2018;89(11):581-586

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.

Objectives: Maintaining proper nutrition during pregnancy is crucial for pregnant women and especially for who have been diagnosed with type 1 diabetes mellitus (T1DM) or who develop gestational diabetes mellitus (GDM).

Material And Methods: To measure differences in vitamin and mineral intakes among women with normal pregnancies, pregnant women with GDM, and pregnant women with pre-gestational T1DM; and to assess the women's dietary intakes in comparison with Polish nutritional guidelines. The analysis was conducted among 83 pregnant women (29 GDM patients, 26 T1DM patients and 28 normal pregnancy participants) from whom we collected seven-day 24-hour dietary records during the second part of their pregnancies. Read More

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http://dx.doi.org/10.5603/GP.a2018.0100DOI Listing
January 2018
10 Reads

Amniotic fluid NF-kB concentration in pregnant women with a high risk of prenatal screening test results.

Ginekol Pol 2018 ;89(10):577-580

Kafkas University School of Medicine, Kars, Turkey.

Objectives: Nuclear factor-kappa beta (NF-kB) can potentially be related to certain fetal chromosomal abnormalities. This study aimed to determine whether the concentration of NF-kB changes in the amniotic fluid (AF) of pregnant women who have a high risk of fetal down syndrome (DS) results in prenatal screening and diagnosis testing.

Material And Methods: 108 patients with an abnormal first trimester combined screening test (FTCST) were subjected to amniocentesis and fetal karyotype analysis between 16 and 20 weeks of gestation. Read More

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http://dx.doi.org/10.5603/GP.a2018.0099DOI Listing
January 2018

The powerful association of angiotensin-converting enzyme insertion/deletion polymorphism and idiopathic recurrent pregnancy loss.

Authors:
Evren Gumus

Ginekol Pol 2018 ;89(10):573-576

Department of Medical Genetics, Faculty of Medicine, University of Harran, 63000 Sanliurfa, Turkey.

Objectives: Idiopathic recurrent pregnancy loss (IRPL) is one of the most troublesome complications of pregnancy. Several researches were also conducted to search the possible association with ACE I/D polymorphism and IRPL. In the light of these reports, this case-control study was investigated to genotypes and alleles of ACE I/D polymorphism in IRPL group and control group. Read More

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http://dx.doi.org/10.5603/GP.a2018.0098DOI Listing
January 2018
8 Reads

Assessment of diagnostic utility of multivariate diagnostic models in differential diagnosis of ovarian tumors.

Ginekol Pol 2018 ;89(10):568-572

Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Poland.

Introduction: Ovarian cancer (OC) diagnosis remains a clinical challenge due to lack of early symptoms and insufficient accuracy of the available diagnostic methods. The purpose of this study was to determine whether osteopontin could be useful in differential diagnosis of ovarian tumors.

Material And Methods: Serum samples from 92 patients qualified for surgical treatment due to ovarian mass were divided into 2 groups according to the histopathological result: OC including borderline ovarian tumors (n = 39) and benign ovarian tumors (BOTs) (n = 53). Read More

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http://dx.doi.org/10.5603/GP.a2018.0097DOI Listing
January 2018
10 Reads

The role of the βKlotho gene in uterine endometrial cancer.

Ginekol Pol 2018 ;89(10):563-567

Clinical Department of Oncological Gynecology, II Department of Gynecology and Obstetrics, Medical University of Lodz, Poland, Poland.

Objectives: Endometrial cancer is the most common cancer of the female genital organs in developed countries, accounting for approximately 50% of all gynecological cancers. The Klotho gene was discovered in 1997 as an anti-aging gene that, when overexpressed, may extend the lifespan, but when disrupted, may be a factor responsible for premature aging syndrome. The aim of the study is to assess the relationship between the clinical and pathological features of endometrial cancer and βKlotho gene expression. Read More

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http://dx.doi.org/10.5603/GP.a2018.0096DOI Listing
January 2018
4 Reads

New porcine model of perineal tear and its utility in physicians' training on the reconstruction of 3rd and 4th degree perineal tear during vaginal delivery.

Ginekol Pol 2018 ;89(10):558-562

Warsaw Proctology Centre, Saint Elisabeth Hospital, Warsaw, Poland, Poland; Department of General Surgery, District Hospital in Wołomin, Poland, Gdynska 1/3, 05-200 Wolomin, Poland.

Objectives: One of the most serious complications of vaginal delivery is 3rd and 4th degree perineal tear and its incorrect management results in anal incontinence. Animal-based anatomical models of childbirth-induced perineal tear are an important element of the physicians' practical training [1]. The proposed new model, prepared using porcine tongue and intestine, closely mimics all the tissues and organs subjected to injury during complicated deliveries and constitutes an educational opportunity for the reconstruction of the injuries. Read More

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http://dx.doi.org/10.5603/GP.a2018.0095DOI Listing
January 2018
8 Reads

A comparison of pelvic organ prolapse and sexual function after abdominal and laparoscopic hysterectomy.

Ginekol Pol 2018 ;89(10):553-557

Health Sciences University Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey.

Objectives: Hysterectomy is one of the risk factors of pelvic organ prolapse (POP). There is no consensus on whether the route of hysterectomy affects the subsequent development of POP. The aim of the study was to assess POP and sexual function 1 year after a hysterectomy when comparing total abdominal hysterectomy (TAH) with total laparoscopic hysterectomy (TLH). Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0094DOI Listing
January 2018
9 Reads

Occult uterine leiomyosarcoma in women undergoing abdominal and minimally invasive surgeries for myomas.

Ginekol Pol 2018 ;89(10):546-552

Department of Gynecology and Oncology, Jagiellonian University, Krakow, 31 501 Krakow, Poland.

Objectives: To estimate (i) the incidence of occult uterine leiomyosarcoma (LMS) in patients operated on for presumedmyomas, and (ii) the proportion of occult LMS to preoperatively diagnosed LMS in a tertiary center.

Material And Methods: An Institutional Review Board-approved retrospective cohort study was performed. The electronicdatabase of 30,476 patients was searched for women who had undergone surgery due to presumed myomas (N = 2675) as well as those with uterine LMS recognized via histology (N = 10) between January 2010 and December 2016. Read More

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http://dx.doi.org/10.5603/GP.a2018.0093DOI Listing
January 2018
1 Read

Expression profiling of genes modulated by rosmarinic acid (RA) in MCF-7 breast cancer cells.

Ginekol Pol 2018 ;89(10):541-545

Department of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, 62-064 Poznan, Poland.

Objectives: Cancer is the second most common cause of death, with breast cancer (BC) as the most frequently diagnosed neoplasm among females. The origin of BC is multifactorial and depends on environmental and genetic factors. The disease presents a significant challenge due to its drug resistance and frequent metastasis. Read More

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http://dx.doi.org/10.5603/GP.a2018.0092DOI Listing
January 2018
2 Reads

Common Methylenetetrahydrofolate Reductase Polymorphisms (A1298C & C677T) in Ectopic Trophoblasts and Methotrexate Treatment Failure in Tubal Pregnancies.

Ginekol Pol 2018 ;89(10):536-540

Department of Obstetrics and Gynecology, Adnan Menderes University Hospital, Aytepe, 09100 Aydin, Turkey.

Objectives: The success rate of methotrexate (MTX) therapy varies among tubal ectopic pregnancies. Common methylenetetrahydrofolate reductase (MTHFR) polymorphisms (C677T&A1298C) have been suggested to alter MTX effect. This study aimed to assess and compare MTX treatment failure rates with respect to MTHFR polymorphisms in trophoblasts of ectopic tubal pregnancies. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0091DOI Listing
January 2018
18 Reads

Hysterectomy in Poland between 2011 and 2016. Changing trends in the surgical approach to hysterectomy.

Ginekol Pol 2018 ;89(10):529-535

Division of Surgical Oncology, Gynaecological Oncology, Chemotherapy and Department of Oncology, Wroclaw Medical University, Plac Ludwika Hirszfelda 12, 53-413 Wroclaw, Poland; Lower Silesian Oncology Center in Wrocław, Poland.

Objectives: In Poland, approximately 35,000 women a year undergo hysterectomy. The surgical approach may vary depending on the indications and experience of the operator and advances in laparoscopic surgical techniques. The aim of the present study was to analyze trends in the use of various types of hysterectomy in Poland between 2011 and 2016. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0090DOI Listing
January 2018
12 Reads

Gestational diabetes mellitus - literature review on selected cytokines and hormones of confirmed or possible role in its pathogenesis.

Ginekol Pol 2018 ;89(9):522-527

Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University in Lublin, Lublin, Poland, 8 Jaczewskiego Street, 20-954 Lublin, Poland; Department of Endocrinology, Medical University in Lublin, Lublin, Poland, 8 Jaczewskiego Street, 20-954 Lublin, Poland.

The incidence of gestational diabetes mellitus (GDM) increases globally, including Poland. Considering serious consequences of gestational diabetes for both mother and fetus, screening for this disorder is an obligatory element of managing pregnant woman. The pathogenesis of gestational diabetes is not yet thoroughly explained. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0089DOI Listing
January 2018
7 Reads

The role of visfatin in pathogenesis of gestational diabetes (GDM).

Ginekol Pol 2018 ;89(9):518-521

Department of Obstetrics and Women's Diseases, Poznan University of Medical Sciences, Poland.

Gestational diabetes (GDM) is defined as a glucose intolerance of varying severity with onset or first recognition during pregnancy. Two major metabolic disorders: insulin resistance and β-cells dysfunction, play currently major role in pathogenesis of GDM. Adipose tissue is an organ involved in production of adipokines, which have various influence on metabolism of glucose and lipids. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0088DOI Listing
January 2018
9 Reads

Ocular perfusion pressure and intraocular pressure in pregnant women with severe preeclampsia.

Ginekol Pol 2018 ;89(9):513-517

Kafkas University School of Medicine, Kars, Turkey.

Objectives: The aim of this study was to investigate whether severe preeclampsia (SPE) affects intraocular pressure (IOP) and ocular perfusion pressure (OPP).

Material And Methods: This prospective and comparative study included 64 pregnant females, allocated into 2 groups as Group 1 (31 pregnant women with SPE) and Group 2 (33 normotensive pregnant women). IOP, systolic and diastolic blood pressure, OPP of all the subjects were measured after 20 weeks of gestation and prior to labor and medical therapy. Read More

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http://dx.doi.org/10.5603/GP.a2018.0087DOI Listing
January 2018

Dietary supplementation usage by pregnant women in Silesia - population based study.

Ginekol Pol 2018 ;89(9):506-512

Department of Epidemiology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Medykow 18 Str, 40-752 Katowice, Poland.

Objectives: Despite wide access to gynecological and obstetric advice, informational campaigns, and information online and in magazines aimed at pregnant women, there is a worryingly high percentage of women who still do not use recommended dietary supplementation. The aim of this study was to assess the frequency of micronutrient supplementation by pregnant women and to specify the determinants that impact decisions concerning supplementation.

Material And Methods: A cross-sectional survey was conducted between June 2016 and May 2017 among a group of pregnant women visiting gynecological and obstetric clinics in the Silesia region, who have completed an authorized questionnaire developed for the purpose of this study. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0086DOI Listing
January 2018
12 Reads

Does endocan level increase in women with polycystic ovary syndrome? A case - control study.

Ginekol Pol 2018 ;89(9):500-505

Department of Obstetrics and Gynecology, Gaziosmanpasa University, Tokat, Turkey.

Objectives: To evaluate endocan levels of patients with polycystic ovary syndrome (PCOS) in comparison to healthy women.

Material And Methods: A cross-sectional case-control study on 88 patients with PCOS (mean age, 22.06 ± 4. Read More

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http://dx.doi.org/10.5603/GP.a2018.0085DOI Listing
January 2018
2 Reads

Gynaecological robotic surgery at a state hospital - our own experience.

Ginekol Pol 2018 ;89(9):495-499

University of Health Sciences, Erzurum Regional Traditional Hospital (Nenehatun Maternity Hospital), 25070 Erzurum, Turkey; Health Ministry Nenehatun Maternity Hospital, Health Ministry Nenehatun Maternity Hospital, Erzurum, Turkey, 25070 Erzurum, Turkey.

Objectives: In recent years, the rapid development of minimally invasive surgical methods, including robotic surgery, has resulted in a marked decline of the traditional methods in gynaecological surgery. The aim of the study was to share our experience with robotic surgery at a state hospital.

Material And Methods: A total of 40 patients, who underwent robotic gynaecological surgery (GS) between 2015 and 2017, were included. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0084DOI Listing
January 2018
8 Reads

Pre-vaccination prevalence of high-risk human papillomaviruses (HPV) in women from Kosovo and their related sociodemographic characteristics.

Ginekol Pol 2018 ;89(9):485-494

Department of Obstetrics and Gynecology, University Clinical Center of Kosovo, University "Hasan Prishtina", Lagja e Spitalit n.n, 10000, Prishtina, Kosovo..

Objectives: Kosovo's current health care system does not support organized nationwide cervical cancer screening and human papillomavirus (HPV) vaccination programs. To date, no reliable data are available on cervical cancer incidence and mortality in Kosovo, or on high-risk HPV (HR-HPV) prevalence and HPV type distribution. Our aim is to determinate the pre-vaccination prevalence and distribution of HR-HPVs and to assesses the associations between sociodemographic characteristics and increased risk of HPV infection in women from Kosovo. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/vie
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http://dx.doi.org/10.5603/GP.a2018.0083DOI Listing
January 2018
14 Reads

A new technique in laparoscopic abdominal access (Evsen Method, Modified Veress Technique).

Ginekol Pol 2018 ;89(9):481-484

DİCLE UNİVERSİTY, DİYARBAKIR/TURKEY, 21200 DİYARBAKIR, Turkey.

Objectives: The most important step in laparoscopic surgery is to safely establish the pneumoperitoneum, especially since approximately half of the complications occur during the initial entry into the abdomen. There is a distinct need to modify the available methods to reduce therate of adverse events in laparoscopic entry. In this study, a modified Veress technique (MVT) or Evsen method is introduced. Read More

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http://dx.doi.org/10.5603/GP.a2018.0082DOI Listing
January 2018
5 Reads

Simple vaginal trachelectomy for early stage cervical cancer: A tertiary cancer center experience.

Ginekol Pol 2018 ;89(9):475-480

Objectives: Less radical fertility sparing procedures have been introduced to reduce morbidity and adverse obstetric outcome in cervical cancer. Our objective was to describe oncological and obstetric outcomes of women with early-stage cervical cancer who underwent a simple vaginal trachelectomy (SVT).

Material And Methods: From 01/2013 to 05/2017, 14 women underwent SVT preceded by laparoscopic pelvic lymph node dissection. Read More

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https://journals.viamedica.pl/ginekologia_polska/article/dow
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https://journals.viamedica.pl/ginekologia_polska/article/vie
Publisher Site
http://dx.doi.org/10.5603/GP.a2018.0081DOI Listing
January 2018
20 Reads