5,932 results match your criteria Giardiasis


[THE ITERATIVE APPROACH TO PRICING LABORATORY SERVICES FOR THE PROVISION OF MEDICAL AID (COPROPROCYCOSOPHICAL EXAMINATION ON LYAMBLIOSIS)].

Georgian Med News 2018 Nov(284):136-140

Kharkiv Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine; Yaroslav Mudriy National Law University, Kharkiv, Ukraine.

The purpose of the study was to substantiate the theoretical and methodical principles of pricing for laboratory services in the diagnosis of giardiasis, taking into account their iterability and peculiarities of parasitic research methods. The methods of laboratory study of gum disease of native smear, treated with Lyulol solution, and ether-formalin enrichment on the criteria of their quality and effectiveness are analyzed. On the basis of the study of the effectiveness of the first and repeated analyzes, the conclusion on the iterative nature of laboratory studies of giardiasis and the effectiveness of the use of an iterative approach to the determination of prices for laboratory services is substantiated. Read More

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November 2018
2 Reads

Comparative Analysis of Antigiardial Potential of Heat Inactivated and Probiotic Protein of Probiotic Lactobacillus rhamnosus GG in Murine Giardiasis.

Probiotics Antimicrob Proteins 2019 Jan 4. Epub 2019 Jan 4.

Department of Microbiology, Basic Medical Sciences, Panjab University, (Block-1), South Campus, Chandigarh, 160014, India.

The present study was designed to envisage the antigiardial efficacy of killed probiotic and probiotic protein (PP) of Lactobacillus rhamnosus GG in murine giardiasis. Experimentally, it was observed that animal administered either with probiotic protein emulsified with adjuvant (PP + Giardia) or killed probiotic (killed probiotic (i/p) + Giardia) had significantly reduced Giardia cycle with respect to observed severity and duration of giardiasis compared with Giardia-infected mice. Further, it was found that animals belonging to PP + Giardia and killed probiotic (i/p) + Giardia had significantly high levels of antigiardial IgA antibody and nitric oxide both in serum and in intestinal fluid compared with Giardia-infected and counter control mice. Read More

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http://link.springer.com/10.1007/s12602-018-9506-8
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http://dx.doi.org/10.1007/s12602-018-9506-8DOI Listing
January 2019
1 Read

Study on Giardia duodenalis and Cryptosporidium spp. infection in veterinarians in Poland.

Ann Agric Environ Med 2018 Dec 18;25(4):732-733. Epub 2018 Dec 18.

Institute of Rural Health, Lublin, Poland.

The risk of exposure to zoonotic factors among veterinarians comprises still underestimated problem. Many etiological factors of infectious diseases are so far poorly known, including the way of their transmission from environment to humans and their impact for health. The main aim of the study was to determine the risk of two selected zoonosis infections caused by Giardia duodenalis and Cryptosporidium spp. Read More

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http://dx.doi.org/10.26444/aaem/101576DOI Listing
December 2018

Lactoferrin and lactoferricin endocytosis halt Giardia cell growth and prevent infective cyst production.

Sci Rep 2018 Dec 21;8(1):18020. Epub 2018 Dec 21.

Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC - CONICET, Universidad Nacional de Córdoba, Córdoba, 5000, Argentina.

Lactoferrin (LF) is an 80 KDa iron-binding glycoprotein that plays a significant role in the innate immune system and is considered to be an important microbicide molecule. It has been suggested to be effective in the treatment of giardiasis, an intestinal disease caused by the protozoan parasite G. lamblia. Read More

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http://dx.doi.org/10.1038/s41598-018-36563-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303297PMC
December 2018

Cross-sectional epidemiological investigations of Giardia lamblia in children in Pakistan.

Sao Paulo Med J 2018 Sep-Oct;136(5):449-453

MSc, PhD. Microbiologist and Assistant Professor, Department of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.

Background: The prevalence of Giardia lamblia in Pakistani children is currently unknown. The aim here was to evaluate the prevalence and risk factors of Giardia lamblia in children exhibiting diarrhea.

Design And Setting: Cross-sectional study at different district healthcare hospitals in Pakistan. Read More

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http://dx.doi.org/10.1590/1516-3180.2018.0350060918DOI Listing
August 2018
3 Reads

Treatment of refractory paediatric giardiasis using secnidazole plus albendazole: a case series.

Infez Med 2018 Dec;26(4):379-384

Academic Paediatric Hospital "Centro Habana", Benjumeda y Morales, Cerro, La Habana, Cuba.

Giardia lamblia, the aetiological agent of human giardiasis, is a frequently identified protozoan infection of the upper small intestine. It mainly affects children and has a wide range of clinical manifestations, from asymptomatic carriage to acute or chronic diarrhoea with dehydration, abdominal pain, nausea, vomiting, excessive flatulence and weight loss. Standard treatment for giardiasis is commonly with 5-nitroimidazole (5-NI) compounds, or nitazoxanide; however, some individuals experience treatment failure. Read More

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December 2018
4 Reads

Prevalence of intestinal parasites and the absence of soil-transmitted helminths in Añatuya, Santiago del Estero, Argentina.

Parasit Vectors 2018 Dec 14;11(1):638. Epub 2018 Dec 14.

Fundación Mundo Sano, Paraguay, 1535, Buenos Aires, Argentina.

Background: Intestinal parasites (IP) have been reported in point studies from different provinces of Argentina. The presence of soil-transmitted helminths (STH) was detected in many of these studies, including varied prevalences of all five species of STH in the north were the climate is more appropriate for transmission. Nonetheless, Argentina lacks a comprehensive prevalence map of STH. Read More

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http://dx.doi.org/10.1186/s13071-018-3232-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295026PMC
December 2018

Persistent Occurrence of and Subtypes in a Welfare Institute.

Front Microbiol 2018 20;9:2830. Epub 2018 Nov 20.

Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.

Few data are available on the transmission dynamics of intestinal protozoa in children in welfare institutes. In this study, fecal specimens were collected from 396 children in a welfare institute in Shanghai, China during December 2011 (207 specimens), June 2012 (78 specimens), and September 2013 (111 specimens), and examined for spp., , and by PCR analysis of the small subunit rRNA, triosephosphate isomerase, and internal transcribed spacer genes, respectively. Read More

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http://dx.doi.org/10.3389/fmicb.2018.02830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256193PMC
November 2018
1 Read

Comparative effect of manuka honey on anaerobic parasitic protozoans with standard drug therapy under conditions: A preliminary study.

Indian J Pharmacol 2018 Jul-Aug;50(4):197-203

Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: From the past five decades, metronidazole and tinidazole have been used for treating nonresistant and resistant giardiasis and trichomoniasis. However, due to the occurrence of drug resistance to standard therapy idealizes us to explore some additional therapies which is cost-effective, easy accessibility, and natural which has least side effects. Manuka honey obtained from is well known for its antibacterial and wound healing properties and is thought to be a better option as an additional therapy. Read More

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http://dx.doi.org/10.4103/ijp.IJP_227_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234710PMC
December 2018
1 Read
0.679 Impact Factor

Prolonged duodenal mucosal lymphocyte alterations in patients with and without post infectious functional gastrointestinal disorders after Giardia infection.

J Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway.

Objective: Persisting low grade inflammation is suggested to play a role in post-infectious functional gastrointestinal disorders (PI-FGID). The present study examined alterations in duodenal mucosal lymphocytes during and after Giardia gastroenteritis in patients who did, or did not, develop PI-FGID.

Design: Duodenal mucosal intraepithelial lymphocytes (IELs) and lamina propria CD3, CD4, CD8 and CD20 lymphocytes were quantified in 28 chronic giardiasis (CG) patients, 66 patients with persistent abdominal symptoms after acute Giardia infection (PI-FGID), 19 recovered controls (RC) and 16 healthy volunteers (HC). Read More

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http://dx.doi.org/10.1093/infdis/jiy690DOI Listing
November 2018
2 Reads

Treatment-refractory giardiasis: challenges and solutions.

Infect Drug Resist 2018 24;11:1921-1933. Epub 2018 Oct 24.

Norwegian National Advisory Unit on Tropical Infectious Diseases, Department of Medicine, Haukeland University Hospital, Bergen, Norway.

is the commonest parasitic diarrheal pathogen affecting humans and a frequent cause of waterborne/foodborne parasitic diseases worldwide. Prevalence of giardiasis is higher in children, living in poor, low hygiene settings in developing countries, and in travelers returning from highly endemic areas. The clinical picture of giardiasis is heterogeneous, with high variability in severity of clinical disease. Read More

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http://dx.doi.org/10.2147/IDR.S141468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207226PMC
October 2018
1 Read

Effect of Hydroalcoholic Extract on Cysts Compared with Metronidazole in Vitro.

Iran J Parasitol 2018 Jul-Sep;13(3):486-492

Dept. of Pharmacology and Toxicology, Urmia Branch, Islamic Azad University, Urmia, Iran.

Background: Giardiasis, an intestinal infection, is made by the flagellate protozoan and on the other hand, positive effects of plants derivatives, especially phenolic derivatives, against giardiasis. The effect of (OV) hydroalcoholic extract is still uninvestigated. Thus, this study was conducted to evaluate the effect of OV hydroalcoholic extract on cysts compared with metronidazole in vitro. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243170PMC
November 2018
2 Reads

Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity.

J Med Chem 2018 Nov 23. Epub 2018 Nov 23.

Tuberculosis and parasitic diseases, such as giardiasis, amebiasis, leishmaniasis and trypanosomiasis, all urgently require improved treatment options. Recently, it has been shown that anti-tubercular bicyclic nitroimidazoles such as pretomanid and delamanid have potential as repurposed therapeutics for the treatment of visceral leishmaniasis. Here we show that pretomanid also possesses potent activity against Giardia lamblia and Entamoeba histolytica, thus expanding the therapeutic potential of nitroimidazo-oxazines. Read More

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http://dx.doi.org/10.1021/acs.jmedchem.8b01578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311682PMC
November 2018
1 Read

Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins.

Mol Biochem Parasitol 2019 Jan 17;227:29-38. Epub 2018 Nov 17.

Department of Cell and Molecular Biology, BMC, Box 596, Uppsala University, SE-751 24, Uppsala, Sweden. Electronic address:

Giardia intestinalis is a protozoan parasite and the causative agent of giardiasis, a common diarrheal disease. Cysteine protease (CP) activities have been suggested to be involved in Giardia's pathogenesis and we have recently identified and characterized three secreted Giardia CPs; CP14019, CP16160 and CP16779. Here we have studied the cleavage specificity of these CPs using substrate phage display and recombinant protein substrates. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01666851183009
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http://dx.doi.org/10.1016/j.molbiopara.2018.10.004DOI Listing
January 2019
8 Reads

Highly Potent 1-1,2,3-Triazole-Tethered Isatin-Metronidazole Conjugates Against Anaerobic Foodborne, Waterborne, and Sexually-Transmitted Protozoal Parasites.

Front Cell Infect Microbiol 2018 30;8:380. Epub 2018 Oct 30.

Department of Chemistry, Guru Nanak Dev University, Amritsar, India.

Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in tropical and subtropical regions of the world. Metronidazole (MTZ) is the current drug of choice for amebiasis, giardiasis, and trichomoniasis but it has several adverse effects and potential resistance is a concern. In order to develop alternative antimicrobials, a library of 1-1,2,3-triazole-tethered metronidazole-isatin conjugates was synthesized using Huisgen's azide-alkyne cycloaddition reaction and evaluated for their amebicidal, anti-trichomonal, and anti-giardial potential. Read More

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https://www.frontiersin.org/article/10.3389/fcimb.2018.00380
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http://dx.doi.org/10.3389/fcimb.2018.00380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218680PMC
October 2018
3 Reads

Development of Molecular Diagnosis Using Multiplex Real-Time PCR and T4 Phage Internal Control to Simultaneously Detect Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis from Human Stool Samples.

Korean J Parasitol 2018 Oct 31;56(5):419-427. Epub 2018 Oct 31.

Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul 03080, Korea.

This study aimed to develop a new multiplex real-time PCR detection method for 3 species of waterborne protozoan parasites (Cryptosporidium parvum, Giardia lamblia, and Cyclospora cayetanensis) identified as major causes of traveler's diarrhea. Three target genes were specifically and simultaneously detected by the TaqMan probe method for multiple parasitic infection cases, including Cryptosporidium oocyst wall protein for C. parvum, glutamate dehydrogenase for G. Read More

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http://dx.doi.org/10.3347/kjp.2018.56.5.419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243187PMC
October 2018

A spatial analysis of giardiasis and cryptosporidiosis in relation to public water supply distribution in North West England.

Spat Spatiotemporal Epidemiol 2018 Nov 13;27:61-70. Epub 2018 Oct 13.

CHICAS, Lancaster Medical School, Lancaster University, LA1 4YW United Kingdom.

Giardia and Cryptosporidium are both waterborne parasites and leading causes of gastroenteritis. Although specimens from diarrhoeic patients are routinely examined for Cryptosporidium, they are often not examined for Giardia so many cases go undiagnosed. Since 2002, all faecal specimens in Central Lancashire have been tested for infection with Giardia and Cryptosporidium. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18775845173005
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http://dx.doi.org/10.1016/j.sste.2018.09.002DOI Listing
November 2018
15 Reads

A Rare Complication of Giardiasis in Children: Protein-losing Enteropathy.

Pediatr Infect Dis J 2018 Dec;37(12):e345-e347

From the Division of Pediatric Gastroenterology, Hepatology and Nutrition.

Protein-losing enteropathy may develop as a complication of a wide spectrum of diseases. Three cases of giardiasis that presented with acute onset of hypoalbuminemia were documented, and resolution of protein loss after treatment was also confirmed. Thus, chronic enteric infections should be considered as an etiology of severe intestinal protein loss, particularly in children. Read More

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http://dx.doi.org/10.1097/INF.0000000000002025DOI Listing
December 2018
10 Reads

Giardia: an under-reported foodborne parasite.

Int J Parasitol 2018 Nov 1. Epub 2018 Nov 1.

College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.

Foodborne zoonotic pathogens are a serious public health issue and result in significant global economic losses. Despite their importance to public health, epidemiological data on foodborne diseases including giardiasis caused by the enteric parasite, Giardia duodenalis, are lacking. This parasite is estimated to cause ∼28. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00207519183024
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http://dx.doi.org/10.1016/j.ijpara.2018.07.003DOI Listing
November 2018
8 Reads

Improving basic skills in celiac-like disease diagnosis: a case report.

BMC Gastroenterol 2018 Nov 3;18(1):162. Epub 2018 Nov 3.

Gastroenterology and Gastrointestinal Endoscopy Unit, Sant'Andrea University Hospital, "Sapienza" University of Rome, Rome, Italy.

Background: The diagnosis of Coeliac disease (CD) requires a combination of sign/symptoms, positivity of specific antibodies and duodenal histological evidence of villous atrophy. Duodenal villous atrophy, despite representing the CD landmark, is not specific since it is found in many gastrointestinal disorders. Giardiasis is one of the most common human intestinal protozoan infestations in industrialized countries whose histological duodenal mucosa damage could mimic that of CD. Read More

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https://bmcgastroenterol.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12876-018-0894-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215663PMC
November 2018
4 Reads

Activity of Thioallyl Compounds From Garlic Against Trophozoites and in Experimental Giardiasis.

Front Cell Infect Microbiol 2018 15;8:353. Epub 2018 Oct 15.

Departamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.

Fresh aqueous extracts (AGEs) and several thioallyl compounds (TACs) from garlic have an important antimicrobial activity that likely involves their interaction with exposed thiol groups at single aminoacids or target proteins. Since these groups are present in trophozoites, in this work we evaluated the anti-giardial activity of AGE and several garlic's TACs. susceptibility assays showed that AGE affected trophozoite viability initially by a mechanism impairing cell integrity and oxidoreductase activities while diesterase activities were abrogated at higher AGE concentrations. Read More

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http://dx.doi.org/10.3389/fcimb.2018.00353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196658PMC
October 2018
10 Reads

Molecular detection and genotyping of pathogenic protozoan parasites in raw and treated water samples from southwest Colombia.

Parasit Vectors 2018 Oct 26;11(1):563. Epub 2018 Oct 26.

Grupo de Investigaciones Microbiológicas-UR (GIMUR), Programa de Biología, Facultad de Ciencias Naturales y Matemáticas, Universidad del Rosario, 110111, Bogotá, Colombia.

Background: Protozoan parasites such as Giardia duodenalis, Cryptosporidium spp., Cyclospora cayetanensis, Toxoplasma gondii and Entamoeba histolytica represent a great challenge to the systems producing water for human consumption because their cystic forms are persistent in the environment and resist to the disinfection methods conventionally used for their control. In this study, we investigated the presence of these protozoan pathogens in both raw and treated water samples used for the production of drinking water in Nariño Department, southwest Colombia. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13071-018-3147-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203992PMC
October 2018
9 Reads

Genetics and serology of celiac disease during giardiasis.

Scand J Gastroenterol 2018 Oct 24. Epub 2018 Oct 24.

b Genetic, Cardiovascular and Nutritional Diseases Laboratory , Setif-1 University , Setif , Algeria.

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http://dx.doi.org/10.1080/00365521.2018.1508612DOI Listing
October 2018
1 Read
2.329 Impact Factor

The Influence of Climate and Livestock Reservoirs on Human Cases of Giardiasis.

Ecohealth 2018 Oct 22. Epub 2018 Oct 22.

Department of Population Medicine, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada.

Giardia duodenalis is an intestinal parasite which causes diarrhoeal illness in people. Zoonotic subtypes found in livestock may contribute to human disease occurrence through runoff of manure into multi-use surface water. This study investigated temporal associations among selected environmental variables and G. Read More

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http://dx.doi.org/10.1007/s10393-018-1385-7DOI Listing
October 2018
1 Read

Giardia duodenalis in the UK: current knowledge of risk factors and public health implications.

Parasitology 2018 Oct 15:1-12. Epub 2018 Oct 15.

The Moredun Research Institute,Pentlands Science Park,Bush Loan,Penicuik,Scotland EH26 0PZ,UK.

Giardia duodenalis is a ubiquitous flagellated protozoan parasite known to cause giardiasis throughout the world. Potential transmission vehicles for this zoonotic parasite are both water and food sources. As such consumption of water contaminated by feces, or food sources washed in contaminated water containing parasite cysts, may result in outbreaks. Read More

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http://dx.doi.org/10.1017/S0031182018001683DOI Listing
October 2018
1 Read

Endoscopic findings in patients with familial Mediterranean fever and dyspeptic symptoms.

Prz Gastroenterol 2018 5;13(3):234-241. Epub 2018 Jul 5.

Department of Paediatric Allergy and Immunology, Medical Faculty, Cukurova University Sarıcam, Adana, Turkey.

Aim: The aim of the study was to evaluate the clinical, endoscopic, histopathological, laboratory, and imaging findings of patients with familial Mediterranean fever (FMF) presenting with dyspeptic symptoms.

Material And Methods: Endoscopy was performed in 28 patients with FMF undergoing colchicine therapy, who presented to our hospital between 2012 and 2014 with abdominal pain, diarrhoea, and dyspeptic complaints. Upper gastrointestinal system endoscopy was performed in all patients; 16 of these underwent colonoscopy. Read More

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https://www.termedia.pl/doi/10.5114/pg.2018.76954
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http://dx.doi.org/10.5114/pg.2018.76954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173081PMC
July 2018
8 Reads

Ocular Parasitosis Caused by Protozoan Infection during Travel: Focus on Prevention and Treatment.

Int J Prev Med 2018 17;9:79. Epub 2018 Sep 17.

Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

International travel is rising quickly worldwide. Many people travel to tropical and subtropical areas, where there has been increasing exposure of travelers to infectious pathogens. Ocular parasitic infections are more prevalent in these geographical areas and they can lead to morbidity and mortality, often due to late or misdiagnosis due to the unfamiliarity of health staff with these diseases. Read More

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http://dx.doi.org/10.4103/ijpvm.IJPVM_161_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151969PMC
September 2018
11 Reads

Stunting, Beyond Acute Diarrhoea: Giardia Duodenalis, in Cambodia.

Nutrients 2018 Oct 3;10(10). Epub 2018 Oct 3.

United Nations Children's Fund (UNICEF), Integrated Early Childhood Development, Exchange Square, 5th Floor, No. 19&20, Street 106, Sangkat Wat Phnom, Khan Daun Penh, Phnom Penh 12100, Cambodia.

Background: The adverse outcomes of malnutrition on the development of a child are well acknowledged as are the broad variety of contextual factors that may impact child nutritional status. Adequate nutrient intake and the adoption of appropriate water, sanitation and hygiene measures are largely documented for their positive influence on health. Improved sanitation and protection from human feces can significantly lower the incidence of diarrhea and environmental enteropathy. Read More

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http://www.mdpi.com/2072-6643/10/10/1420
Publisher Site
http://dx.doi.org/10.3390/nu10101420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213534PMC
October 2018
9 Reads

Giardiasis: Characteristics, Pathogenesis and New Insights About Treatment.

Curr Top Med Chem 2018 ;18(15):1287-1303

Departamento de Ingenieria. Area Farmacia y Tecnologia Farmaceutica. Universidad Miguel Hernández de Elche, Elche, Spain.

Giardia intestinalis infection causes enterocytes damage and loss of brush border of the epithelial cells of the intestine that leads to shortening of microvilli and altered epithelial barrier function. This pathology results in aqueous diarrhoea, steatorrhea, nausea, abdominal pain, vomiting and weight loss. However, most infections are asymptomatic. Read More

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http://dx.doi.org/10.2174/1568026618666181002095314DOI Listing
January 2018
5 Reads

Epidemiology and associated risk factors of giardiasis in a peri-urban setting in New South Wales Australia.

Epidemiol Infect 2018 Sep 28:1-9. Epub 2018 Sep 28.

Public Health Unit,South Western Sydney Local Health District,Liverpool,Australia.

Giardiasis is one of the most important non-viral causes of human diarrhoea. Yet, little is known about the epidemiology of giardiasis in the context of developed countries such as Australia and there is a limited information about local sources of exposure to inform prevention strategies in New South Wales. This study aimed to (1) describe the epidemiology of giardiasis and (2) identify potential modifiable risk factors associated with giardiasis that are unique to south-western Sydney, Australia. Read More

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http://dx.doi.org/10.1017/S0950268818002637DOI Listing
September 2018
3 Reads

First report of Giardia duodenalis infection in bamboo rats.

Parasit Vectors 2018 Sep 20;11(1):520. Epub 2018 Sep 20.

College of Veterinary Medicine, Northwest A&F University, 22 Xinong Road, Yangling, 712100, People's Republic of China.

Background: The zoonotic parasite, Giardia duodenalis (syns. G. lamblia and G. Read More

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http://dx.doi.org/10.1186/s13071-018-3111-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149208PMC
September 2018
1 Read

Comparison of three commercial multiplex PCR assays for the diagnosis of intestinal protozoa.

Parasite 2018 18;25:48. Epub 2018 Sep 18.

Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, 35033, Rennes, France.

Although microscopic examination of stool samples remains the reference method for the diagnosis of intestinal protozoal infections, these techniques are time-consuming and require operators who are experienced and well trained. Molecular biology seems to offer performances at least equivalent in terms of sensitivity and specificity for certain parasites. This study aimed to compare three multiplex PCR assays on 93 prospectively collected positive stools (prospective cohort) and a panel of 12 more Cryptosporidium-positive samples (Cryptosporidium panel). Read More

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http://dx.doi.org/10.1051/parasite/2018049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144649PMC
January 2019

Knowledge, Attitude, and Practice on Hygiene and Morbidity Status among Tertiary Students: The Case of Kotebe Metropolitan University, Addis Ababa, Ethiopia.

J Environ Public Health 2018 29;2018:2094621. Epub 2018 Aug 29.

Department of Urban Environmental Management, Kotebe Metropolitan University, P.O. Box 31248, Addis Ababa, Ethiopia.

Considerable fractions of the world's diseases are communicable, of which over 60% are infectious. Knowledge, attitude, and practice of hygiene are very important to decrease these disease burdens especially in places like higher education institutions. This study is aimed at revealing the status and gaps on knowledge, attitude, and practice of hygiene among Kotebe Metropolitan University students. Read More

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http://dx.doi.org/10.1155/2018/2094621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136465PMC
August 2018
1 Read

Effects of Decavanadate Salts with Organic and Inorganic Cations on Escherichia coli, Giardia intestinalis, and Vero Cells.

Inorg Chem 2018 Oct 10;57(19):11930-11941. Epub 2018 Sep 10.

Fundação Osvaldo Cruz, Av. Brazil , Manguinhos , 4365 Rio de Janeiro , Brazil.

Decavanadate salts with nicotinamide (3-pyridinecarboxamide, 3-pca) and isonicotinamide (4-pyridinecarboxamide, 4-pca) in both neutral and protonated forms, (3-Hpca)[HVO]·2HO·2(3-pca) (complex I) and (4-Hpca)[HVO]·2(4-pca) (complex II), have been synthesized and characterized by vibrational spectroscopy (infrared and Raman), thermogravimetric analysis (TGA), V NMR, and single-crystal X-ray diffraction analysis. The effects of sodium decavanadate (henceforth called NaV) and compounds I and II on Escherichia coli, Giardia intestinalis, and Vero (African green monkey epithelial kidney) cells were evaluated. Enhanced growth inhibitory activity against E. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.8b01298DOI Listing
October 2018
1 Read

Recent advances in the Giardia-host relationship reveal danger lurking behind the smile.

PLoS Negl Trop Dis 2018 09 6;12(9):e0006625. Epub 2018 Sep 6.

Department of Biology, Georgetown University, Washington, DC, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0006625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126833PMC
September 2018

Intestinal parasites among employees of restaurants and cafeterias in a city of Brazil.

Rev Salud Publica (Bogota) 2017 Sep-Oct;19(5):691-696

MS: Pharmaceutical Chemist. Professor, Departamento de Ciências Farmacêuticas. Universidade Federal do Espírito Santo. São Mateus, Brazil.

Objective : To investigate the frequency of intestinal parasites in employees of restaurants and cafeterias located in the Commercial Center of São Mateus, Espírito Santo, one of the oldest cities of Brazil.

Material And Methods : Between August 2013 and February 2014, 42 fecal samples were collected and analyzed by spontaneous sedimentation method in the Clinical Analysis Laboratory of the Federal University of Espírito Santo, São Mateus Campus.

Results : The results were positive in 19 % of the samples. Read More

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http://dx.doi.org/10.15446/rsap.V19n5.57263DOI Listing
January 2019

Occurrence and genotyping of Giardia duodenalis and Cryptosporidium in pre-weaned dairy calves in central Sichuan province, China.

Parasite 2018 4;25:45. Epub 2018 Sep 4.

Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Sichuan 611130, PR China.

Giardia duodenalis and Cryptosporidium spp. are common human and animal pathogens. They have increasingly been reported in dairy calves in recent years; however, multilocus genotyping information for G. Read More

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https://www.parasite-journal.org/10.1051/parasite/2018046
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http://dx.doi.org/10.1051/parasite/2018046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121785PMC
January 2019
7 Reads

Effect of probiotic Saccharomyces boulardii in experimental giardiasis.

Benef Microbes 2018 Sep 31;9(5):789-797. Epub 2018 Aug 31.

1 Department of Parasitology, Federal University of Minas Gerais, Av. Pres. Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 MG, Brazil.

The aim of the study was to assess the efficacy of Saccharomyces boulardii in experimental treatment of giardiasis and its impact on intestinal integrity and some functions of gerbils infected with Giardia lamblia. 28 gerbils (Meriones unguiculatus), aged 4-6 weeks, were divided into four groups: untreated and uninfected control (CT); infected with G. lamblia (IGL); treated with S. Read More

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https://www.wageningenacademic.com/doi/10.3920/BM2017.0155
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http://dx.doi.org/10.3920/BM2017.0155DOI Listing
September 2018
9 Reads

Preliminary Comparison of an in-House Real-Time PCR with the Automated BD Max Enteric Parasite Panel for the Detection of Giardia intestinalis.

J Parasitol 2018 Dec 29;104(6):702-704. Epub 2018 Aug 29.

1   Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024 Negrar, Verona, Italy.

Giardia intestinalis is a parasite that commonly causes diarrheal disease throughout the world. An accurate and rapid diagnosis is essential to reduce the infection. Classical diagnosis of giardiasis is performed by microscopic examination of stool samples, but in recent years many DNA-based methods have been developed. Read More

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http://dx.doi.org/10.1645/17-149DOI Listing
December 2018
15 Reads

Association of intestinal pathogens with faecal markers of environmental enteric dysfunction among slum-dwelling children in the first 2 years of life in Bangladesh.

Trop Med Int Health 2018 Nov 10;23(11):1242-1250. Epub 2018 Sep 10.

Nutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.

Objective: Environmental Enteric Dysfunction (EED) can be assessed by faecal biomarkers such as Myeloperoxidase (MPO), Neopterin (NEO) and Alpha-1 anti-trypsin (AAT). We aimed to test the association of intestinal pathogens with faecal markers of EED among slum-dwelling children in first 2 years of life.

Methods: The MAL-ED birth cohort data of Bangladesh site were used to conduct this analysis. Read More

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http://dx.doi.org/10.1111/tmi.13141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282798PMC
November 2018
7 Reads

Parasitic infections of the gut in children.

Paediatr Int Child Health 2018 Aug 22:1-8. Epub 2018 Aug 22.

a Tropical Gastroenterology and Nutrition group , University of Zambia School of Medicine , Lusaka , Zambia.

Parasitic infections of the gut have major implications for child health, but many questions remain unanswered. Protozoal parasites, especially cryptosporidiosis and giardiasis, cause diarrhoea and contribute to impaired growth, neurocognitive development and mortality. Entamoeba histolytica causes dysentery and may have more subtle effects on child growth. Read More

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https://www.tandfonline.com/doi/full/10.1080/20469047.2018.1
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http://dx.doi.org/10.1080/20469047.2018.1479055DOI Listing
August 2018
9 Reads

Intestinal parasitism and nutritional status among indigenous children from the Argentinian Atlantic Forest: Determinants of enteroparasites infections in minority populations.

Acta Trop 2018 Nov 17;187:248-256. Epub 2018 Aug 17.

Department of Environmental and Global Health, University of Florida, Gainesville, FL 32610, USA; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.

Objective: Intestinal parasitoses, especially in the less favored populations of tropical and subtropical areas, are a scourge of high impact in public health. We conducted a cross-sectional survey to investigate the prevalence of helminths and protozoa pathogens, malnutrition, and their determinants in children from indigenous Mbyá Guaraní villages of Iguazú, in the subtropical Atlantic Forest of Argentina.

Methods: Parasitological assessment was performed using a combination of flotation, sedimentation, and centrifugation techniques, as well as temporal and permanent stains. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.08.015DOI Listing
November 2018
8 Reads

Rapid diagnostic tests relying on antigen detection from stool as an efficient point of care testing strategy for giardiasis and cryptosporidiosis? Evaluation of a new immunochromatographic duplex assay.

Diagn Microbiol Infect Dis 2019 Jan 25;93(1):33-36. Epub 2018 Jul 25.

Laboratoire de Parasitologie-Mycologie, Institut de Biologie, CHU Nantes. Electronic address:

Microscopy is the gold standard for the diagnosis of gastrointestinal parasites but is time-consuming and dependent on operator skills. Rapid diagnostic tests represent alternative methods but most evaluations have been conducted on a limited number of samples preventing their implementation in the clinical setting. We evaluated a new CE-IVD marked immunochromatographic assay (Crypto/Giardia K-SeT®, Coris Bioconcept) for the detection of G. Read More

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http://dx.doi.org/10.1016/j.diagmicrobio.2018.07.012DOI Listing
January 2019
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Efficacy of mebendazole in paediatric patients with giardiasis: A systematic review and meta-analysis.

Acta Trop 2018 Dec 6;188:50-57. Epub 2018 Aug 6.

University of the Basque Country, UPV/EHU and CIBERSAM, Medical School-Department of Neuroscience, Barrio Sarriena S/N, Leioa, Spain.

Mebendazole (MBZ), a benzimidazole compound, has received attention in treating patients with giardiasis because it has shown beneficial effects both in vitro and in vivo. The aim of this study was to assess with a systematic review and meta-analysis of randomized controlled trials (RCTs) the efficacy of MBZ compared to other antigiardial agents in children. We searched RCTs of MBZ for the treatment of Giardia infections published in PubMed and EBSCOhost. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.08.001DOI Listing
December 2018
10 Reads

Comparative performance of reference laboratory tests and in-clinic tests for Giardia in canine feces.

Parasit Vectors 2018 Aug 1;11(1):444. Epub 2018 Aug 1.

College of Veterinary Medicine, Cornell University, C4-114 VMC, 930 Campus Rd, Ithaca, NY, 14853, USA.

Background: We examined the performance of four in-clinic Giardia diagnostic tests by comparing results to three laboratory methods for detection of Giardia. A set of 177 fecal samples originally submitted to a commercial laboratory by veterinarians for routine ova and parasite (O&P) testing was used. Specimens were examined by direct immunofluorescence assay (DFA) for presence of Giardia cysts which served as the gold standard. Read More

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http://dx.doi.org/10.1186/s13071-018-2990-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090814PMC
August 2018
2 Reads

Comparing four diagnostic tests for Giardia duodenalis in dogs using latent class analysis.

Parasit Vectors 2018 Jul 31;11(1):439. Epub 2018 Jul 31.

Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Background: To accurately diagnose giardiosis in dogs, knowledge of diagnostic test characteristics and expected prevalence are required. The aim of this work was to estimate test characteristics (sensitivity and specificity) of four commonly used diagnostic tests for detection of Giardia duodenalis in dogs.

Methods: Fecal samples from 573 dogs originating from four populations (household dogs, shelter dogs, hunting dogs and clinical dogs) were examined with centrifugation sedimentation flotation (CSF) coproscopical analysis, direct immunofluorescence assay (DFA, Merifluor Cryptosporidium/Giardia®), a rapid enzyme immunochromatographic assay (IDEXX SNAP Giardia®) and qPCR (SSU rDNA) for presence of G. Read More

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http://dx.doi.org/10.1186/s13071-018-3014-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069568PMC
July 2018
1 Read

Multilocus genotyping of Giardia duodenalis isolates from household cats and pet shop kittens.

Vet Parasitol 2018 Aug 28;259:44-48. Epub 2018 Jun 28.

Laboratory of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, Higashi 23-35-1, Towada, Aomori 034-8628, Japan.

Giardia duodenalis is a pathogenic protozoan that causes diarrhea in mammalian hosts including humans and companion animals, and the host specificity differs depending on the genetic assemblages. The purpose of the present study is to perform multilocus genotyping at four loci of G. duodenalis isolates from household cats and pet shop kittens in Japan and evaluate the zoonotic potential. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.06.022DOI Listing
August 2018
6 Reads

Age patterns of Cryptosporidium species and Giardia duodenalis in dairy calves in Egypt.

Parasitol Int 2018 Dec 25;67(6):736-741. Epub 2018 Jul 25.

Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. Electronic address:

Little is known of the occurrence and age patterns of species/genotypes and subtypes of Cryptosporidium spp. and Giardia duodenalis in calves in Egypt. In this study, 248 fecal specimens were collected from dairy calves aged 1 day to 6 months on eight farms in three provinces during March 2015 to April 2016. Read More

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http://dx.doi.org/10.1016/j.parint.2018.07.012DOI Listing
December 2018
11 Reads
1 Citation
2.111 Impact Factor

A natural zoonotic giardiasis: Infection of a child via Giardia cysts in pet chinchilla droppings.

Parasitol Int 2018 Dec 24;67(6):759-762. Epub 2018 Jul 24.

Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic. Electronic address:

Here, we report a case of direct zoonotic transmission of giardiasis between a pet chinchilla and a human. Microscopic and molecular examinations of stool samples from a child and samples of chinchilla droppings revealed cysts/DNA of Giardia intestinalis. The transmission from the chinchilla to the child has been confirmed as coprophagous after the 1-year-old toddler ingested pet chinchilla droppings. Read More

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http://dx.doi.org/10.1016/j.parint.2018.07.010DOI Listing
December 2018
3 Reads

Methodological innovations for the study of irreplaceable samples reveal giardiasis in extinct animals (Nothrotherium maquinense and Palaeolama maior).

Parasitol Int 2018 Dec 25;67(6):776-780. Epub 2018 Jul 25.

Pontifícia Universidade Católica de Minas Gerais, Avenida Dom José Gaspar, 290 Coração Eucarístico, Belo Horizonte, Estado de Minas Gerais CEP: 30535-901, Brazil.

The use of diagnostic methods that prevent irreplaceable samples (from museum collections, archaeological and paleontological samples) of being consumed or that increase their yield is relevant. For museum collections, archaeological and paleontological samples it is essential to conserve samples, subsamples or portions for future research. We are addressing methods for conservation of irreplaceable samples that could be fully consumed. Read More

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http://dx.doi.org/10.1016/j.parint.2018.07.011DOI Listing
December 2018
2 Reads