135 results match your criteria Giant Condylomata Acuminata of Buschke and Lowenstein


Successful treatment of giant condyloma in a pediatric heart transplant recipient with topical cidofovir.

Transpl Infect Dis 2018 Dec 28;20(6):e12989. Epub 2018 Sep 28.

Department of Pediatrics, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, Texas.

We report a case of giant condyloma that developed in a pediatric heart transplant recipient. This infection progressed for several months despite reduction in immunosuppression, topical treatment, and oral cimetidine therapy. Complete resolution was observed following 7 months of topical cidofovir, without evidence of systemic toxicity or rejection. Read More

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http://doi.wiley.com/10.1111/tid.12989
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http://dx.doi.org/10.1111/tid.12989DOI Listing
December 2018
25 Reads

Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618758348. Epub 2018 Feb 15.

Kern Medical Center, Bakersfield, CA, USA.

Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. Read More

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http://dx.doi.org/10.1177/2324709618758348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818086PMC
February 2018
23 Reads

A case of reccuring giant condyloma of vulva in infant without sexual abuse successfully treated with electrocoagulation in Benin.

Pan Afr Med J 2017 30;27:159. Epub 2017 Jun 30.

Dermatology-Venereology, Faculty of Health, Cotonou, University of Abomey-Calavi, R. Benin.

We report here a case of giant vulval condyloma in a two-year-old infant infected by her "baby sitter" without sexual abuse. Treated by surgical excision coupled with electrocoagulation, it was noted a rapid recurrence two weeks after treatment requiring a second electrocoagulation session. More than a year later, no lesion was noted, thus demonstrating therapeutic success. Read More

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http://dx.doi.org/10.11604/pamj.2017.27.159.11998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567949PMC
September 2017
14 Reads

[Buschke-Löwenstein tumor].

Pan Afr Med J 2016;25:176. Epub 2016 Nov 18.

Service de Dermatologie, CHU Hassan II, Fès, Maroc.

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http://dx.doi.org/10.11604/pamj.2016.25.176.10622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326042PMC
April 2018
8 Reads

[Buschke-Lowenstein tumors].

Hautarzt 2017 Mar;68(3):199-203

Hautklinik, Universitätsklinikum der RWTH-Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.

Background: A giant condyloma acuminatum which shows destructive growth but lacking invasion is designated as a Buschke-Lowenstein tumor (BLT).

Objectives: Classification of the BLT and therapeutic guidelines are provided.

Materials And Methods: A MEDLINE literature search from 2006-2016 was performed. Read More

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http://dx.doi.org/10.1007/s00105-016-3924-xDOI Listing
March 2017
5 Reads

Anal verrucous carcinoma is not related to infection with human papillomaviruses and should be distinguished from giant condyloma (Buschke-Löwenstein tumour).

Histopathology 2017 May 24;70(6):938-945. Epub 2017 Feb 24.

Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Aims: Verrucous carcinoma (VC) is a variant of well-differentiated squamous cell carcinoma and in the anal region is regarded as synonymous with giant condyloma (Buschke-Löwenstein tumour) (BLT). Aetiology, diagnostic criteria and clinical behaviour of both lesions are controversial. Recent studies suggest that VC at other sites is not associated with human papillomaviruses (HPV). Read More

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http://dx.doi.org/10.1111/his.13158DOI Listing
May 2017
26 Reads

Successful improvement of Buschke-Löwenstein tumour in an HIV-infected patient with antiretroviral therapy alone.

BMJ Case Rep 2016 Nov 21;2016. Epub 2016 Nov 21.

Hopitaux Universitaires Henri Mondor, Creteil, France.

Buschke-Löwenstein tumour (BLT), also defined as giant condyloma acuminatum, is a rare exophytic tumour affecting the anogenital and perianal regions associated with human papillomavirus (HPV) infections, with a potential of malignant transformation and which is at a greater risk in T-cell mediated immunodeficient patients. Different therapeutic options, alone or in combination, have been reported for the treatment of BLT including local therapy but wide surgical local excision is however recommended as the most important therapeutic intervention. We report a case of a HIV-infected man who developed a voluminous pelvic BLT which disappeared progressively under antiretroviral therapy with no additional treatment, contemporary to an improvement of his immunity, highlighting the possible spontaneous reversibility of HPV-induced tumours in treated HIV infection. Read More

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http://dx.doi.org/10.1136/bcr-2016-217753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129144PMC
November 2016
11 Reads

Giant Perineal Condyloma Acuminatum (Buschke-Lowenstein Tumour): A Case Report.

Chirurgia (Bucur) 2016 Sept-Oct;111(5):435-438

The giant condyloma acuminatum, also known as Buschke- Lowenstein tumor (BLT), is a rare sexually-transmitted disease. Moreover, the condyloma acuminatum produced by Human Papilloma Virus (HPV) infection becomes one the most common sexually-transmitted infection which affects the perineal region. Under such situations, the first therapeutic option is surgical excision. Read More

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http://dx.doi.org/10.21614/chirurgia.111.5.435DOI Listing
February 2017
5 Reads

Giant Condyloma (Buschke-Loewenstein Tumor) in a 16-year-old Patient: Case Report.

Rev Bras Ginecol Obstet 2016 Sep 27;38(9):471-476. Epub 2016 Oct 27.

Gynecology and Obstetrics Department, Ribeirão Preto Faculty of Medicine, USP, Ribeirão Preto, SP, Brazil.

The Buschke-Loewenstein tumor is characterized by excessive growth of verrucous lesions on the genitals and/or perianal region. It is considered benign despite the high rate of recurrence and the possibility of malignant transformation. It is commonly associated with subtypes 6 and 11 of the human papillomavirus (HPV), and host's immunity plays an important role in the development of the disease. Read More

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http://dx.doi.org/10.1055/s-0036-1593776DOI Listing
September 2016
11 Reads

Metastatic Giant Condyloma Acuminata (Buschke-Löwenstein Tumor).

J Oncol Pract 2016 10;12(10):951-953

University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1200/JOP.2016.013441DOI Listing
October 2016
4 Reads

Invasive squamous cell carcinoma originating from a giant penile condyloma.

Int J STD AIDS 2017 May 23;28(6):619-622. Epub 2016 Feb 23.

3 Department of Pathology, Izmir Training and Research Hospital, Izmir, Turkey.

In this case study, we present an unusual case with squamous cell carcinoma originating from a giant condyloma acuminata completely surrounding the penis. A 57-year-old circumcised heterosexual male patient presented with a penile lesion existing for 20 years. Incisional biopsy revealed acanthosis of the squamous epithelium. Read More

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http://dx.doi.org/10.1177/0956462416635361DOI Listing
May 2017
4 Reads

Giant anal tumor.

Cir Esp 2016 Oct 11;94(8):481. Epub 2016 Feb 11.

Servicio de Cirugía General y Digestiva, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, España.

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http://dx.doi.org/10.1016/j.ciresp.2015.12.013DOI Listing
October 2016
4 Reads

Rapidly Invasive Buschke-Löwenstein Tumor Associated With Human Papillomavirus Types 6 and 52.

Sex Transm Dis 2015 Oct;42(10):547-8

From the *Dermatology and Venereology Unit, Department of Pathophysiology and Organ Transplantation, University of Milan Medical School, Milan, Italy; †Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; and ‡Divisions of Urology and §Pathology, Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Buschke-Löwenstein tumor, or giant condyloma acuminatum, represents a rare, sexually transmitted disorder, with a slow evolution and the tendency to infiltrate in the adjacent tissues associated with human papillomavirus (HPV). This article reports the first case of male Buschke-Löwenstein tumor associated with HPV6 and HPV52. Read More

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http://pdfs.journals.lww.com/stdjournal/2015/10000/Rapidly_I
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/OLQ.0000000000000346DOI Listing
October 2015
26 Reads

Giant Condyloma Acuminatum of Vulva Frustrating Treatment Challenge.

World J Plast Surg 2015 Jul;4(2):159-62

Department of Plastic Surgery, Shahid Beheshti University of Medical Sciences, Modaress Hospital, Tehran, Iran.

Giant condylomata are not usually seen nowadays in developed nations, but such cases are still seen in the under-resourced countries. Condylomata acuminata are commonly transmitted through sexual intercourse. Generally diagnosed based on their appearance. Read More

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http://www.wjps.ir/article-1-170-en.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537608PMC
July 2015
23 Reads

Giant condyloma acuminatum of the scrotum, bilateral groins, and suprapubic region: a treatment and reconstruction challenge.

Am Surg 2015 May;81(5):E215-7

Department of Surgery, University of South Alabama, Mobile, Alabama, USA.

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May 2015
4 Reads

Electrocautery resection, shaving with a scalpel, and podophyllin: a combination therapy for giant condyloma acuminatum.

World J Mens Health 2015 Apr 23;33(1):39-41. Epub 2015 Apr 23.

Department of Urology, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Giant condyloma acuminatum (also known as Buschke-Löwenstein tumor) is a rare disease, for which the treatment of choice is still controversial. In the case described in this report, we used a combination of electrocautery and a surgical scalpel to resect a huge genital wart, followed by long-term local treatment with podophyllin. This procedure was relatively fast, easy to perform, involved minimal bleeding, and did not result in any complications. Read More

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http://dx.doi.org/10.5534/wjmh.2015.33.1.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412007PMC
April 2015
5 Reads

Perianal giant condyloma acuminatum of Buschke-Loewenstein: a carcinoma-like condyloma or a condyloma-like carcinoma?

ANZ J Surg 2015 May;85(5):394-5

Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology 'Sapienza', St. Andrea Hospital, Rome, Italy.

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http://dx.doi.org/10.1111/ans.12913DOI Listing
May 2015
15 Reads
1.120 Impact Factor

Buschke - Loewenstein tumor resection with simultaneous reconstruction of extensive tissue losses: case report.

BMC Surg 2015 Apr 10;15:41. Epub 2015 Apr 10.

The Chair and Department of General, Endocrine and Gastroenterological Oncology Surgery, Karol Marcinkowski University of Medical Sciences in Poznań, ul. Przybyszewskiego 49, 60-355, Poznań, Poland.

Background: Giant condyloma acuminatum or Buschke - Loewenstein tumor is a very rare disease usually located in the genital, anorectal, and perianal regions. It is locally invasive but in mostly cases displays a benign cytology on preoperative tissue sampling. Because of its low incidence little is known about treatment outcomes. Read More

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http://dx.doi.org/10.1186/s12893-015-0026-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399229PMC
April 2015
12 Reads

Circumferential anal giant condyloma acuminatum: a new surgical approach.

Dis Colon Rectum 2015 Apr;58(4):e49-52

Istituti Clinici Zucchi, Università degli Studi Milano-Bicocca, Milan, Italy.

Introduction: Perianal giant condyloma acuminatum is a rare clinical condition related to human papillomavirus infection and characterized by a circumferential, exophytic, cauliflower-like mass with an irregular warty surface localized in the anal region.

Technique: A circular incision with a diathermocoagulator was performed on macroscopically healthy skin, 1 cm from the margin of the lesion. The dermis was divided from the subcutaneous tissue. Read More

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http://dx.doi.org/10.1097/DCR.0000000000000339DOI Listing
April 2015
5 Reads

Giant condylomata acuminata of Buschke and Lowenstein: A peristomal variant.

Int J Surg Case Rep 2014 30;5(12):1014-7. Epub 2014 Oct 30.

York Hospital, York, UK. Electronic address:

Introduction: Giant condylomata acuminata (GCA) is a rare, locally invasive tumour that may undergo malignant transformation. It was first described a HPV-induced penile tumour which clinically resembled both a squamous cell carcinoma and condyloma acuminatum, often arising from a pre-existing warty lesion. We describe a case of peri-stomal GCA transformation into invasive squamous cell carcinoma (SCC), which is, to our knowledge, the first report of this in the literature. Read More

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http://dx.doi.org/10.1016/j.ijscr.2014.10.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275778PMC
December 2014
5 Reads

Periurethral and vulval condylomata acuminata: an unusual juvenile venereal disease in a 3-year-old girl.

BMJ Case Rep 2014 Sep 8;2014. Epub 2014 Sep 8.

Department of Paediatric Dermatology and Venereal diseases, UCLH and GOSH, London, UK.

We present a case of giant condyloma acuminatum (CA) in a 3-year-old girl with rapidly growing vulval and periurethral lesions, which was investigated thoroughly and successfully treated with excision biopsy. Genital warts in the form of giant alarming vestibular, vulval and periurethral lesions of CA are very rare in children. There is need for a multidisciplinary approach with potential sociomedicolegal implications. Read More

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http://dx.doi.org/10.1136/bcr-2013-200997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158202PMC
September 2014
10 Reads

Giant condyloma acuminatum - Buschke-Lowenstein disease - a literature review.

Chirurgia (Bucur) 2014 Jul-Aug;109(4):445-50

Aim: Buschke-Lowenstein disease or giant condyloma acuminatum represents a rare, sexually transmitted disorder, with a slow evolution and the tendency to infiltrate in the adjacent tissues; untreated, the outcome is unfavorable. The hallmark is the development of one or various prominent-sized vegetant tumors that usually ulcerate.

Material And Methods: The present article summarizes both the etiopathogenic features and the current approach of treatment management. Read More

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November 2014
4 Reads

Giant condyloma acuminatum in the axilla.

Acta Derm Venereol 2015 Mar;95(3):355-6

Department of Dermatology, Isesaki Municipal Hospital, 12-1 Tsunatori-honcho, Isesaki, Japan.

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http://dx.doi.org/10.2340/00015555-1935DOI Listing
March 2015
3 Reads

Perianal giant condyloma acuminatum (Buschke-Löwenstein tumor).

Authors:
Santosh Shenoy

Skinmed 2014 Mar-Apr;12(2):114-5

A 50-year-old heterosexual, HIV-negative man presented with a giant anal condyloma (Figure). He had iron deficiency anemia, a slow-growing anal wart for many years, and intermittent bleeding and pruritus. Esophagogastroduodenoscopy and colonoscopy findings were normal. Read More

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July 2014
6 Reads

Psychotic depression due to giant condyloma Buschke-Löwenstein tumors.

Rom J Morphol Embryol 2014 ;55(1):189-95

Department of Psychiatry, "Carol Davila" University of Medicine and Pharmacy, 1st Department of Psychiatry, "Prof. Dr. Alexandru Obregia" Clinical Psychiatry Hospital, Bucharest, Romania;

Unlabelled: A 63-year-old patient, with no psychiatric history, was admitted in the psychiatric department with depressed mood, loss of interest in activities, apathy, insomnia, attention deficit, irritability, social withdrawal, prejudice and abandon delusions. Cerebral computed tomography (CT) scan was normal but the general physical examination revealed a voluminous tumor in the inguino-pubic-ano-genital area measuring 350/80/40 mm, which appeared 15 years ago and grew gradually leading to local rickety hygiene and also to depression, especially in the last time period when the tumor grew faster. The DSM-IV-TR diagnostic was affective disorder due to general medical condition. Read More

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April 2015
15 Reads

Detection of human papillomavirus type 56 in giant condyloma acuminatum.

Acta Derm Venereol 2014 Jul;94(4):482-3

Department of Dermatology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.

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http://dx.doi.org/10.2340/00015555-1755DOI Listing
July 2014
8 Reads

[A woman with a growing mass near the anus].

Ned Tijdschr Geneeskd 2013 ;157(41):A6617

Medisch Centrum Alkmaar, afd. Heelkunde, Alkmaar.

A 58-year-old woman visited the surgical outpatient clinic because of a mass near the anus that had existed for years and had now grown to a size that made sitting impossible. With histological examination of the 6 x 10 cm exofytic, condylomatic mass, the diagnosis 'giant condyloma acuminatum' was made. Radical excision was performed, the patient recovered well. Read More

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May 2014
5 Reads

Giant condyloma acuminata of Buschke-Lowenstein: successful treatment mainly by an innovative surgical method.

Authors:
Ge Qian Huiqian Yu

Dermatol Ther 2013 Sep-Oct;26(5):411-4. Epub 2013 Mar 13.

Department of Dermatology and Venereology, The 2nd Affiliated Hospital of Kunming Medical University, Kunming, China.

Many remedies can be applied to condyloma acuminatum. However, it is the most difficult to treat giant condyloma acuminatum because of bleeding, recurrence, intolerance of patients, etc. After careful physical examination, the present authors found the giant tumor was composed of many smaller cauliflower-like warts with long and thin pedicles. Read More

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http://dx.doi.org/10.1111/dth.12013DOI Listing
June 2014
27 Reads

Giant condyloma in pregnancy.

Tunis Med 2013 Jun;91(6):422-3

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June 2013
9 Reads

Successful treatment of perianal giant condyloma acuminatum in an immunocompromised host with systemic interleukin 2 and topical cidofovir.

JAMA Dermatol 2013 Sep;149(9):1068-70

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamadermatol.2013.5160DOI Listing
September 2013
12 Reads

[Squamous cell carcinoma arising in a giant condyloma acuminatum - Buschke-Löwenstein tumour].

Cir Esp 2013 Oct 26;91(8):e43. Epub 2013 Jun 26.

Cirugía General y Aparato Digestivo, Hospital Clínico San Carlos de Madrid, Madrid, España. Electronic address:

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http://dx.doi.org/10.1016/j.ciresp.2013.01.019DOI Listing
October 2013
6 Reads

[Buschke-Löwenstein tumor].

Pan Afr Med J 2013 10;14:94. Epub 2013 Mar 10.

Service de Dermatologie, CHU Ibn Sina, Université Med V, Souissi, Rabat, Maroc.

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http://dx.doi.org/10.11604/pamj.2013.14.94.2463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664873PMC
September 2013
5 Reads

Primary rectal adenocarcinoma presenting as a giant perianal mass mimicking giant condyloma of Buschke-Lowenstein.

Am Surg 2013 Jun;79(6):E228-30

Department of Surgery, The University of Tennessee Medical Center, Knoxville, Tennessee 37920, USA.

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June 2013
15 Reads

Giant condyloma of the cervix: an uncommon entity associated with low-risk human papilloma virus infection.

Am J Surg Pathol 2013 Feb;37(2):300-4

Department of Pathology, Women's and Perinatal Pathology Division, Brigham and Women's Hospital-Harvard Medical School, Boston, MA 02115, USA.

"Giant Condylomas" of the cervix are very uncommon, and have not been fully characterized in the English literature. We report 4 cases of cervical giant condyloma seen in our practice. Patients were predominantly young and presented with a cervical lesion producing bleeding or a mass effect. Read More

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http://dx.doi.org/10.1097/PAS.0b013e31826d261eDOI Listing
February 2013
3 Reads

Buschke-Lowenstein Tumor.

Acta Med Port 2012 Sep-Oct;25(5):345-7. Epub 2012 Nov 12.

Serviço de Ginecologia, Maternidade Júlio Dinis, Centro Hospitalar do Porto, Porto, Portugal.

Introduction: Giant condyloma acuminatum belongs to a spectrum of diseases with malignant degeneration. Clinically, it presents as exophytic, fungating masses, sometimes with a cauliflower-like morphology.

Case Presentation: We present a case of a 32-year-old female patient with a 180x95x80mm exophytic mass of the vulvar region suggestive of Buschke-Lowenstein Tumour. Read More

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December 2013
5 Reads

Giant condyloma acuminatum quickly growing: case report.

G Chir 2012 Oct;33(10):327-30

Department of Surgery and Oncology Sciences, General Surgery Unit, University of Study of Palermo, Italy.

Background: Giant Condyloma Acuminatum (GCA) is a rare, slow growing, large cauliflower tumor of the penile foreskin and perianal region with benign histologic appearance but high propensity for local invasion and recurrences. GCA is associated with Human Papilloma Virus (HPV) types 6 and 11 and it also has considerable risk of neoplastic transformation into fully invasive squamous cell carcinoma into about 5 years.

Objective: Because of the rarity of perianal GCA, to date there is no general agreement on the best method for treatment. Read More

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October 2012

Giant condylomata (Buschke-Löwenstein tumours): our case load in surgical treatment and review of the current therapies.

Eur Rev Med Pharmacol Sci 2012 Jun;16(6):747-51

Chirurgia Plastica e Ricostruttiva, Dipartimento di Discipline Chirurgiche ed Oncologiche, Università degli Studi di Palermo, Italy.

Background: Buschke-Löwenstein tumour (BLT) or giant condyloma is a verrucous infiltrating lesion, due to a sexually transmitted virus infection, human papilloma virus subtypes 6 and 11. Poor hygiene, promiscuity, chronic irritation and cellular immunocompromised states are often implicated in its genesis. Typical treatment of giant condyloma includes imiquimod cream, podophillin resin, cryotherapy, laser surgery, tangential shave excision with electrocautery. Read More

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June 2012
1 Read

Successful treatment of giant condyloma acuminatum with combination retinoid and interferon-γ therapy.

Int J STD AIDS 2012 Jun;23(6):445-7

Department of Dermatology and Venereology, First Hospital of Jilin University, 71 Xinmin Street, Changchun, Jilin, China.

Giant condyloma acuminatum, or Buschke-Löwenstein tumour, is a unique variant of anogenital warts. It is characterized by locally aggressive behaviour but rarely metastasizes. Many treatment strategies such as radical surgery, radiation and chemotherapy have been used to treat it but their efficacy is often poor and the recurrence rates are high. Read More

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http://dx.doi.org/10.1258/ijsa.2011.011331DOI Listing
June 2012
4 Reads

Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma.

Mod Pathol 2012 Oct 8;25(10):1354-63. Epub 2012 Jun 8.

Unit of Molecular Pathology, Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

The role of human papillomavirus (HPV) infections in the development of verrucous carcinoma, a well-differentiated variant of squamous cell carcinoma with difficult differential diagnosis, is controversial in the literature. In this study, we analysed verrucous carcinoma from different origins for the presence and activity of a broad spectrum of HPV types, and carefully reviewed the histopathological features. A random series of 27 formalin-fixed, paraffin-embedded specimens of verrucous carcinoma was taken, representing the head and neck region (n=6), anogenital area (n=16) and extragenital skin region (n=5). Read More

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http://www.nature.com/articles/modpathol201291
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http://dx.doi.org/10.1038/modpathol.2012.91DOI Listing
October 2012
23 Reads

[Perianal Buschke-Löwenstein tumour].

Ugeskr Laeger 2012 Jun;174(23):1616-7

Kirurgisk Gastroenterologisk Afdeling A, Aarhus Universitetshospital, Aalborg Sygehus, Hobrovej 18-22, 9000 Aalborg, Denmark.

The Buschke-Löwenstein tumour is an extremely rare, slow-growing cauliflower-like mass, also known as giant condyloma acuminantum or verrucous carcinoma. It is located in the anogenital region and is characterized by its large size, locally destructive behaviour and a high recurrence rate. It has not the potentiel to metastasize but malignant transformation can occur. Read More

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June 2012
14 Reads

Therapeutic combination of radiofrequency surgical dissection and oral acitretin in the management of perianal Buschke-Lowenstein tumour: a case report.

Int J STD AIDS 2012 May;23(5):362-4

Gastroenterology Department of Army Veterans General Hospital of Athens, Athens, Greece.

Giant condyloma acuminatum (GCA), or Buschke-Löwenstein tumour (BLT), is a rare large tumour of the anogenital area. It is caused by human papillomavirus genotypes 6 and 11, and it is characterized by aggressive local invasion and frequent recurrences after treatment. Treatment of choice is radical excision, although chemotherapy and radiation are also used in special cases. Read More

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http://dx.doi.org/10.1258/ijsa.2011.011301DOI Listing
May 2012
5 Reads

Buschke -Loewenstein tumor: identification of HPV type 6 and 11.

An Bras Dermatol 2012 Jan-Feb;87(1):131-4

Dermatology and Skin Cancer Center, AC Camargo Hospital, São Paulo, SP, Brazil.

The authors report a case of exuberant giant condyloma acuminatum of Buschke-Loewenstein in a male patient, slow-growing, progressive and with locally destructive behavior in the inguinal, body of the penis, scrotum, perineal and perianal regions. After surgery he showed no signs of recurrence in 20 months of follow-up. The identification of HPV types 6 and 11 was performed using in situ hybridization. Read More

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November 2012
5 Reads

Management of giant anal condyloma by wide local excision and anoplasty.

Colorectal Dis 2012 Nov;14(11):1394-7

Department of Surgery, Hospital Arnau de Vilanova of Valencia, Valencia, Spain.

Aim: Treatment of giant condyloma acuminatum, is controversial, especially in human immunodeficiency virus (HIV)-positive patients, owing to concern over wound healing, complications, risk of progression to carcinoma and a high recurrence rate. The aim of this study was to evaluate the outcome after extensive local excision with V-Y anoplasty.

Method: Nine patients were identified from a prospective database, six of whom were HIV positive. Read More

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http://doi.wiley.com/10.1111/j.1463-1318.2012.03006.x
Publisher Site
http://dx.doi.org/10.1111/j.1463-1318.2012.03006.xDOI Listing
November 2012
3 Reads

Scrotal Buschke-Lowenstein tumor in an AIDS patient.

Sex Transm Dis 2012 Mar;39(3):236-7

Department of Dermatology, The University of Texas Heath Science Center at Houston, Houston, TX 77030, USA.

Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor, is a slow-growing neoplasm notable for its size and presentation in the anogenital region. A viral etiology suggests it should be more common in the immunocompromised; however, few reports exist in the literature. The evaluation, treatment, and role of preventative measures are reviewed. Read More

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https://insights.ovid.com/crossref?an=00007435-201203000-000
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http://dx.doi.org/10.1097/OLQ.0b013e318244ac66DOI Listing
March 2012
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Giant condyloma acuminatum of the anorectum: successful radical surgery with anal reconstruction.

Tumori 2011 Nov-Dec;97(6):805-7

Division of General Surgery B, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Venezian 1, Milan, Italy.

Buschke-Löwenstein tumor, or giant condyloma acuminatum, is a relatively uncommon lesion of the anus with aggressive local invasive behavior which may present as a large warty tumor of the genital region with expansive and destructive growth. Many sporadic reports have been published suggesting various therapeutic strategies. We report a case of Buschke-Löwenstein tumor treated with conservative surgery followed by reconstructive procedures without a loop colostomy Read More

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http://dx.doi.org/10.1700/1018.11100DOI Listing
April 2012
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[Buschke-Lowenstein tumor associated with scrotal melanoma. A case report].

Prog Urol 2012 Jan 20;22(1):70-2. Epub 2011 Apr 20.

Service d'anatomie et cytologie pathologique, CHU Hassan II, Fès, Maroc.

Buschke-Lowenstein tumour (BLT) is a giant condyloma acumina, which is rare entity and represents only 1% of all populace. It is a rare viral disease, essentially transmitted by sexual intercourse, characterized by a potential for malignant transformation, invasion and recurrence after treatment. We report a case of BLT associated with perinea-scrotal melanoma. Read More

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http://dx.doi.org/10.1016/j.purol.2011.02.014DOI Listing
January 2012
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[Buschke-Lowenstein Tumor associated to nasopharyngeal condillomatosis].

Rev Gastroenterol Mex 2011 Jul-Sep;76(3):275-8

Cirugía General y del Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid, España.

Giant Acuminata Condyloma or Buschke-Lowenstein Tumor (BLT) is a rare disease characterized typically by its perineal location, local aggressiveness and its cauliflower-like aspect. BLT is associated with Human Papilloma Virus (HPV) infection. Because malignant transformation of BLT is high, radical local excision and histopathological examination are needed. Read More

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March 2014
3 Reads