169 results match your criteria Giant Condylomata Acuminata of Buschke and Lowenstein


The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.

Int J Mol Sci 2022 Apr 20;23(9). Epub 2022 Apr 20.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Necker Hospital for Sick Children, 75015 Paris, France.

Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor (BLT), is a rare disease of the anogenital region. BLT is considered a locally aggressive tumor of benign histological appearance, but with the potential for destructive growth and high recurrence rates. BLT development is strongly associated with infection with low-risk human papillomaviruses (HPVs), mostly HPV-6 and -11. Read More

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Buske-Lowenstein Tumor: A Rare Cause of Genital Warts.

Cureus 2022 Mar 25;14(3):e23477. Epub 2022 Mar 25.

Emergency Medicine, Envision Physician Services, Plantation, USA.

The Buschke-Löwenstein tumor (BLT), also known as giant condylomata acuminata (GCA), is a pseudo-epithelial proliferation engendered by the human papillomavirus (HPV). Interestingly, its location at the anal margin, or perianal skin, is rare. The authors present the case of a gentleman who became unstable while standing, stating that his ears were ringing. Read More

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Giant anogenital tumor of Buschke-Löwenstein in a patient living with human immunodeficiency virus/acquired immunodeficiency syndrome: a case report.

J Med Case Rep 2022 Mar 18;16(1):116. Epub 2022 Mar 18.

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.

Background: Buschke-Löwenstein tumor is a giant condyloma acuminata infection that is characterized by degeneration, invasion, and recurrence. It is associated with human papilloma virus infection. It develops around the genital and perineal area, sometimes causing a large budding ulcerated lesion. Read More

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Clinical Conundrum: A Case of Cervical Giant Condyloma Acuminatum.

J Obstet Gynaecol Can 2022 Mar;44(3):294-297

Allan Blair Cancer Centre, Regina, SK.

Giant condyloma acuminatum (GCA) is a benign anogenital lesion caused by human papilloma virus. It is rarely found on the cervix and is difficult to differentiate from malignancy. It is associated with a propensity for invasion, recurrence, and malignant transformation. Read More

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A rare case of self-healing giant condyloma acuminatum.

Dermatol Ther 2022 01 17;35(1):e15189. Epub 2021 Nov 17.

Department of Physiotherapy, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.

Giant condyloma acuminatum (GCA) which is also called Buschke-Lowenstein tumor. It is a rare tumor of the anorectal area and external genitalia associated with low-risk HPV types 6 or 11. GCA has a high-rate of recurrence (66%) and malignant transformation (56%). Read More

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January 2022

Buschke-Löwenstein tumour: a rare and challenging entity.

BMJ Case Rep 2021 Sep 16;14(9). Epub 2021 Sep 16.

General Surgery, Hospital da Luz, Vila Nova de Gaia, Portugal.

Buschke-Löwenstein tumour (BLT) is rare and locally aggressive, and malignant transformation is a possibility. Because there is no consensus on the best treatment approach, the authors present a treatment algorithm based on several case reports. A 57-year-old male patient resorted to surgical consultation with a giant perianal cauliflower-like mass. Read More

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September 2021

Radical Surgical Management of Perianal Giant Condyloma Acuminatum of Buschke and Löwenstein: Long-term Results of 11 Cases.

Ann Coloproctol 2021 Aug 23. Epub 2021 Aug 23.

Department of Surgery/Proctology, Memorial Ankara Hospital, Ankara, Turkey.

Purpose: Perianal Buschke-Löwenstein tumor (BLT) is characterized by an exophytic cauliflower-like mass surrounding the perianal region. Its tendency to infiltrate the adjacent tissues, its massiveness, and its high recurrence rate cause difficulties in treatment. The aim of this study is to report our strategy with wide local excision and flap reconstruction for BLT. Read More

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[Giant condyloma acuminatum in pregnancy].

Gynecol Obstet Fertil Senol 2022 02 14;50(2):201-204. Epub 2021 Aug 14.

Service d'anatomie et cytologie pathologique, département de gynécologie-obstétrique et médecine de la reproduction, CHU Grenoble Alpes, 38700 La Tronche, France.

Buschke Lownestein's tumour is a giant acuminate condyloma characterised by its degenerative potential, its invasive nature and its recurrence after treatment. It is a rare condition, transmitted mainly by sexual transmission and induced by to the human papillomavirus (HPV). The discussion will be illustrated by a clinical case The treatment is still under discussion but surgery seems to be the best option. Read More

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February 2022

Management of Giant Groin Mass.

Urology 2021 Oct 8;156:e88-e89. Epub 2021 Aug 8.

University of Colorado Anschutz School of Medicine, Aurora, CO; Department of Surgery/Urology, University of Colorado Anschutz Medical Campus, Aurora, CO; Department of Surgery/Urology, Rocky Mountain Regional VA Medical Center; University of Colorado Anschutz Medical Campus, Aurora, CO. Electronic address:

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October 2021

Giant Condyloma Acuminata (Buschke-Lowenstein Tumor): Review of an Unusual Disease and Difficult to Manage.

Infect Dis Obstet Gynecol 2021 30;2021:9919446. Epub 2021 Jun 30.

Oncology Surgery Department, Hospital Regional de Alta Especialidad del Bajío, León, Guanajuato, Mexico.

Giant condyloma acuminatum (GCA) or Buschke-Loewenstein tumor is a rare disease, with an estimated prevalence of 0.1%. It was initially described in 1896 by Buschke and later in 1925 by Buschke and Loewenstein. Read More

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November 2021

Buschke-Löwenstein tumor in a human immunodeficiency virus-positive patient: a case report and short literature review.

Acta Gastroenterol Belg 2021 Apr-Jun;84(2):343-345

Department of Surgery, Institut Jules Bordet, Bruxelles, Belgium.

Giant condyloma acuminatum, also known as Buschke-Löwenstein tumor, is a rare variant of verrucous carcinoma presenting in the ano-genital region. While its metastatic potential is limited, aggressive local growth is common, with invasion and destruction of the surrounding tissues often causing important therapeutic challenges. Also, data to inform the optimal management approach are scarce and mostly limited to anectodical reports. Read More

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Perianal amebiasis cutis masked by giant condyloma acuminatum in a HIV-seropositive patient.

J Dermatol 2021 Jul 22;48(7):e333-e334. Epub 2021 Apr 22.

Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan.

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Buschke-Lowenstein Tumors: A Review and Proposed Classification System.

Sex Transm Dis 2021 12;48(12):e263-e268

Department of Urology, Tulane School of Medicine, New Orleans, LA.

Abstract: Buschke-Lowenstein (B-L) tumors or giant condylomata are large fungating lesions that are caused by human papillomavirus (HPV) and develop in the anogenital region. Although uncommon, physicians and surgeons who treat sexually transmitted diseases or other diseases involving the anogenital area will encounter these patients. The purpose of this study is to review the current literature regarding these lesions. Read More

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December 2021

A case of giant condyloma acuminatum (Buschke-Lowenstein tumor) successfully treated with acitretin.

Dermatol Ther 2021 05 3;34(3):e14905. Epub 2021 Mar 3.

The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

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Giant Condyloma Acuminatum Treated Successfully with Mild Local Hyperthermia: Two Case Reports.

Acta Derm Venereol 2021 Feb 11;101(2):adv00391. Epub 2021 Feb 11.

Department of Dermatology, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, 110001 Shenyang, China.

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February 2021

Löwenstein-Buschke: Clinicopathologic Analysis of 78 Cases of Large and Giant Condyloma Acuminata of the Anus.

Turk Patoloji Derg 2021 ;37(1):18-25

Department of Pathology, Koç University Hospital, ISTANBUL, TURKEY.

Objective: The nature and clinicopathologic associations of Löwenstein-Buschke disease are unclear.

Materials And Methods: 78 anal condylomatous lesions (≥2 cm) were analyzed. Cases were classified based on size as "medium-large"(2-5 cm, n=59), "large" (5-10 cm, n=13) and "giant" ( > 10 cm, n=6). Read More

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October 2021

Visual Dermatology: Perianal Buschke-Löwenstein Tumor.

J Cutan Med Surg 2021 Sep 11;25(5):560. Epub 2020 Sep 11.

16513 Department of Dermatology, Hospital Son Llàtzer, Palma de Mallorca, Spain.

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September 2021

Giant condyloma acuminatum of Buschke and Löwenstein of the vulva: Successful treatment with diphenylcyclopropenone contact sensitization.

Indian J Dermatol Venereol Leprol 2020 Sep-Oct;86(5):592-594

Department of Dermatology, Chang Gung Memorial Hospital, Taoyuan; Drug Hypersensitivity Clinical and Research Center, Immune-Oncology Center of Excellence, Chang Gung Memorial Hospital, Linkou, Taipei; College of Medicine, Chang Gung University, Taoyuan, Taiwan.

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Complete healing of perianal giant condyloma (buschke-löwenstein tumor) with imiquimod 5% cream alone.

Authors:
F Marino

Tech Coloproctol 2020 12 30;24(12):1313-1314. Epub 2020 Jun 30.

Surgery Unit, National Institute of Gastroenterology "S. de Bellis", Research Hospital, via Turi 27, 70013, Castellana Grotte, BA, Italy.

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December 2020

Treatment of giant condyloma acuminatum with paiteling: A case report.

Dermatol Ther 2020 11 14;33(6):e13936. Epub 2020 Jul 14.

The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

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November 2020

Successful management of giant condyloma acuminatum of vulva with the combination of surgery and photodynamic therapy: Report of two cases.

Photodiagnosis Photodyn Ther 2020 Sep 30;31:101847. Epub 2020 May 30.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha 410011, China. Electronic address:

Patients with condylomata acuminata of the vulva usually have increased difficulty to achieve complete response to treatment and also have a higher risk for disease recurrence. Treatment for this disease varies, including surgical excision, cryotherapy, electrocautery, CO2 laser therapy, topical therapy, and photodynamic therapy (PDT), but none of these alone provides a satisfactory outcome, especially for giant condyloma acuminatum (GCA). We reported two cases of GCA successfully cured with surgical removal, electrocautery and photodynamic therapy. Read More

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September 2020

The Conundrum of an Accumulating Acuminatum.

Am J Case Rep 2020 Feb 23;21:e920516. Epub 2020 Feb 23.

Departmnetal of Internal Medicine, Northwest Hospital, Baltimore, MD, USA.

BACKGROUND A 70-year-old African American man presented with fatigue, dizziness, generalized weakness, and considerable weight loss of over 20 pounds in 3 weeks. History-taking revealed he was positive for HIV, hepatitis C, and severe chronic condyloma acuminatum, which had been progressing for 16 years. Treatment and surgical intervention had been continuously postponed due to the patient's long-standing history of heroin abuse. Read More

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February 2020

"Giant Condyloma Acuminatum (Buschke-Lowenstein tumor): Combined treatment with surgery and chemotherapy."-Further points to be discussed.

Dermatol Ther 2020 03 20;33(2):e13268. Epub 2020 Feb 20.

School of Medicine, Departament of Internal Medicine, Hospital Universitario del Valle, Universidad del Valle, Cali, Colombia.

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Giant condyloma acuminatum (Buschke-Lowenstein tumor): Combined treatment with surgery and chemotherapy.

Dermatol Ther 2020 01 23;33(1):e13193. Epub 2019 Dec 23.

Central Michigan University College of Medicine, Saginaw, Michigan.

We present a case of giant condyloma acuminatum (Buschke-Lowestein tumor) managed with combined treatment of surgery of chemotherapy. Read More

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January 2020

Giant perianal condyloma acuminatum in an infant without sexual abuse.

Arch Pediatr 2019 Nov 10;26(8):473-474. Epub 2019 Oct 10.

Department of Dermatology, Ibn Rochd UHC, 1, quartier des hopitaux, 20000, Casablanca, Morocco.

Giant condyloma acuminatum is rare in infants. We report a case of giant perianal condyloma in a 10-month-old infant without sexual abuse. The patient was treated by surgical excision associated with electrocoagulation with no recurrence after 2 years. Read More

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November 2019

Giant condylomata acuminata of Buschke-Lowenstein.

J Obstet Gynaecol 2020 May 2;40(4):582-583. Epub 2019 Aug 2.

Department of Obstetrics and Gynecology, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.

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Giant condyloma acuminatum in pregnancy: A case report.

Dermatol Ther 2019 07 1;32(4):e12972. Epub 2019 Jul 1.

Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

The giant condyloma acuminatum (GCA), also known as Buschke-Löwenstein tumor (BLT), is a type of human papilloma virus-associated sexually transmitted infection. Treatment options for condyloma acuminatum remain controversial, but surgery seems to be the best option. The management of GCA during pregnancy is more complicated since one has to evaluate the condition of both the mother and the fetus. Read More

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Progression of a Buschke-Lowenstein tumor into invasive squamous cell carcinoma.

JAAPA 2019 Jun;32(6):1-4

Emmanuel K. Fai practices in the Department of Neuroscience at the University of Maryland Medical Center Midtown Campus and in the Department of General Surgery at Laurel Regional Hospital in Laurel, Md. Habib A. Bhutta is a general surgeon in the Department of General Surgery and Kashif Ali is an oncologist in the Department of Medicine at Laurel Regional Hospital. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Buschke-Lowenstein tumors primarily are slow-growing giant condylomata accuminata of the anogenital region. They are locally destructive with a low rate of metastasis. Sexually transmitted oncogenic human papillomavirus type 6 and 11 are the greatest risk factors for Buschke-Lowenstein tumors or verrucous carcinomas, a type of squamous cell cancer. Read More

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