84,466 results match your criteria Giant Condylomata Acuminata of Buschke and Lowenstein
Tierarztl Prax Ausg K Kleintiere Heimtiere 2018 Oct 12;46(5):309-314. Epub 2018 Dec 12.
Cobalamin is a member of the B-group of vitamins and a cofactor for metabolic processes like nucleic acid synthesis, amino acid synthesis, and the citric acid cycle. Mammals are unable to synthesize cobalamin and therefore rely on adequate food intake. Cobalamin absorption is a complex process in the stomach, duodenum, and ileum, requiring a functional exocrine pancreas. Read More
J Hered 2018 Dec 12. Epub 2018 Dec 12.
School of Life Sciences, Arizona State University, Tempe, AZ.
The organisms of the Galapagos Islands played a central role in the development of the theory of evolution by Charles Darwin. Examination of the population genetics factors of many of these organisms with modern molecular methods have expanded our understanding of their evolution. Here I provide a perspective on how selection, gene flow, genetic drift, mutation, and inbreeding have contributed to the evolution of six of the iconic Galapagos species; flightless cormorant, pink iguana, marine iguana, Galapagos hawk, giant tortoises, and Darwin's finches. Read More
Rev Gastroenterol Peru 2018 Jul-Sep;38(3):261-264
Universidad Cooperativa de Colombia. Pasto, Nariño, Colombia.
Peritonitis is one of the main complications of abdominal emergencies. Laparoscopy serves both for the diagnostic and therapeutic management of the acute abdomen; in expert hands the morbimortality of this method is minimal.
Objective: The objective is to verify the efficacy of laparoscopy in patients with secondary peritonitis performing a single surgery without the need for reinterventions, ensuring the least damage of the abdominal wall, avoiding laparotomy. Read More
Int J Syst Evol Microbiol 2018 Dec 12. Epub 2018 Dec 12.
2Department of Marine and Environmental Science, Ocean Genome Legacy Center, Northeastern University, Nahant MA 01908, USA.
A chemolithoautotrophic sulfur-oxidizing, diazotrophic, facultatively heterotrophic, endosymbiotic bacterium, designated as strain 2141T, was isolated from the gills of the giant shipworm Kuphus polythalamius (Teredinidae: Bivalvia). Based on its 16S rRNA sequence, the endosymbiont falls within a clade that includes the as-yet-uncultivated thioautotrophic symbionts of a marine ciliate and hydrothermal vent gastropods, uncultivated marine sediment bacteria, and a free-living sulfur-oxidizing bacterium ODIII6, all of which belong to the Gammaproteobacteria. The endosymbiont is Gram-negative, rod-shaped and has a single polar flagellum when grown in culture. Read More
Chin Med J (Engl) 2018 Dec;131(24):3015-3016
Department of Cardiology, Ajou University School of Medicine, Suwon 16499, Korea.
Nano Lett 2018 Dec 12. Epub 2018 Dec 12.
Modal gain coefficient is a key figure of merit for a laser material. Previously, net modal gain coefficients larger than a few thousand cm-1 were achieved in II-VI and III-V semiconductor gain media, but this required operation at cryogenic temperatures. In this work, using pump-fluence-dependent variable-stripe-length measurements, we show that colloidal CdSe nanoplatelets enable giant modal gain coefficients at room temperature, up to 6,600 cm-1 under pulsed optical excitation. Read More
Arch Orthop Trauma Surg 2018 Dec 11. Epub 2018 Dec 11.
Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.
Introduction: Tenosynovial giant-cell tumor also known as pigmented villonodular synovitis (PVS) is a benign but aggressive synovial proliferative disease most often affecting the knee joint. The mainstay of therapy is surgical resection. Due to a high rate of local recurrence, radiosynoviorthesis (RSO) is used as an adjuvant method in many cases. Read More
Sports Med Int Open 2018 Jul 7;2(4):E105-E112. Epub 2018 Sep 7.
Department of Community Medicine and Rehabilitation, Sports Medicine Unit, Umea University, Umeå, Sweden.
The aim of this study was to investigate the predictive power of aerobic test results and anthropometric variables on FIS-ranking of junior elite alpine skiers. Results from twenty-three male and female adolescent elite alpine skiers from two seasons were included in the multivariate statistical models. Physical work capacity was determined by V̇O2peak, blood lactate concentration ([HLa]b), and heart rate (HR) during ergometer cycling. Read More
Ital J Food Saf 2018 Sep 26;7(3):6846. Epub 2018 Sep 26.
Institute of Tropical Aquaculture.
An aqueous extraction of moringa () leaves were prepared as the edible coats for keeping the quality of the giant freshwater prawn (). In addition, the antioxidant properties and activity; total phenolic content (TPC), total flavonoid contents (TFC), free radical scavenging activity (DPPH), and ferric reducing antioxidant power (FRAP) of moringa leaves were also determined. The phenolic compounds and antioxidant properties in the moringa leaves are low; 16. Read More
Case Rep Pediatr 2018 13;2018:8702568. Epub 2018 Nov 13.
The Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Background: Omphalocele is a rare congenital abdominal wall defect. It is frequently associated with genetic abnormality and other congenital anomalies, although isolated omphalocele cases do exist. Data have shown that omphalocele with co-occurring genetic abnormality has worse prognosis than isolated omphalocele. Read More
Front Microbiol 2018 27;9:2668. Epub 2018 Nov 27.
Aix-Marseille Université, Institut de Recherche pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM); Microbes, Evolution, Phylogeny and Infection (MEΦI); Institut Hospitalo-Universitaire (IHU) - Méditerranée Infection, Marseille, France.
Giant viruses of amoebae were discovered in 2003. Since then, their diversity has greatly expanded. They were suggested to form a fourth branch of life, collectively named 'TRUC' (for "Things Resisting Uncompleted Classifications") alongside , , and . Read More
Indian J Surg Oncol 2018 Dec 30;9(4):578-580. Epub 2018 Jul 30.
Department of Surgical Oncology, Bombay Hospital, Bombay hospital Marg, Marine Drive, Mumbai, Maharashtra 400020 India.
Extraskeletal osteosarcomas are extremely rare and account for < 1% of the soft tissue sarcomas. Most common site is in soft tissues of the lower extremities. Primary osteosarcomas of the breast are extremely rare and only a few cases have been reported in literature. Read More
J Med Case Rep 2018 Dec 12;12(1):366. Epub 2018 Dec 12.
Department of Dermatology and Venereology, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.
Background: Abnormal deposition of calcium in the skin or subcutaneous tissue is termed calcinosis cutis. Idiopathic calcinosis cutis of the scrotum is an uncommon entity. The pathogenesis of idiopathic calcinosis cutis of the scrotum is debatable. Read More
Nano Lett 2018 Dec 11. Epub 2018 Dec 11.
A spherical nanoparticle can scatter tightly focused optical beams in a spin-segmented manner, meaning that the far field of the scattered light exhibits laterally separated left- and right-handed circularly polarized components. This effect, commonly referred to as giant spin Hall effect of light, strongly depends on the position of the scatterer in the focal volume. Here, a scheme that utilizes an optical weak measurement in a cylindrical polarization basis is put forward to drastically enhance the spin-segmentation and, therefore, the sensitivity to small displacements of a scatterer. Read More
J Am Chem Soc 2018 Dec 11. Epub 2018 Dec 11.
The new compound NaCu4Se4 forms by the reaction of CuO and Cu in a molten sodium polyselenide flux, with the existence of CuO being unexpectedly critical to its synthesis. It adopts a layered hexagonal structure (space group P63/mmc with cell parameters a = 3.9931(6) Å and c = 25. Read More
J Cardiol Cases 2014 May 14;9(5):187-188. Epub 2014 Feb 14.
Division of Cardiac Surgery, Spitali Europian - GVM Care & Research, Tiranë, Albania.
Background: Fibroelastomas account for less than 10% of all cardiac tumors, representing the most common valvular and the second most common cardiac benign tumor, following myxomas.Fibroelastomas are histologically benign, but they can result in life-threatening complications such as stroke, acute valvular dysfunction, embolism, ventricular fibrillation, and sudden death.
Methods: A valve-sparing technique with simple shave excision of the tumor was undertaken with success. Read More
J Cardiol Cases 2014 Oct 17;10(4):144-146. Epub 2014 Jul 17.
Department of Echocardiography, Shaheed Rajaei Heart Center, Tehran, Iran.
Congenital aneurysmal dilatation of the left atrium is a rare anomaly that could be associated with supraventricular arrhythmias and life-threatening systemic embolization. We describe a 32-year-old man with a giant left atrial aneurysm diagnosed with new imaging modalities that underwent surgical resection with good results. < Left atrial aneurysms are rare and characterized by their origin from an otherwise normal atrium, a clearly defined communication with the atrial cavity, and their intrapericardial location. Read More
J Cardiol Cases 2014 Jul 1;10(1):31-33. Epub 2014 May 1.
Department of Cardiology, Istanbul Medicine Hospital, Istanbul, Turkey.
We present a case with a giant left ventricular thrombus grown over papillary muscle and chordae tendinae. The patient had declined both surgical and fibrinolytic therapy. After long-term anticoagulation therapy, regression was observed without embolic complication. Read More
J Cardiol Cases 2013 Apr 6;7(4):e109-e113. Epub 2013 Feb 6.
Division of Cardiology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
An 86-year-old woman was admitted to hospital with a head injury secondary to an episode of syncope associated with incontinence. Electrocardiography showed complete atrioventricular block, giant negative T waves in the precordial leads, and QT interval prolongation. Emergency coronary angiography showed no significant coronary stenosis, while left ventriculography demonstrated midventricular ballooning. Read More
J Cardiol Cases 2013 Feb 5;7(2):e57-e59. Epub 2012 Dec 5.
Department of Cardiology, Acibadem University, Istanbul, Turkey.
We report on an 81-year-old woman who presented to hospital with effort dyspnea and leg edema. Transthoracic echocardiography revealed normal left ventricular function but marked dilated ascending aorta with an intimal flap in the proximal ascending aorta, severe tricuspid regurgitation, and severe pulmonary hypertension. Contrast enhanced multi-slice computerized tomography of the chest was performed for detailed evaluation of aortic dissection and this also showed the intimal flap of the ascending aortic dissection (DeBakey type II) and giant ascending aorta (10. Read More
J Cardiol Cases 2013 Feb 8;7(2):e48-e50. Epub 2012 Dec 8.
Department of Second Section of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fuxing Street, Guishan Township, Taoyuan County 33305, Taiwan.
Loss of voice due to vocal cord paralysis, as in Ortner syndrome, is secondary to left recurrent laryngeal nerve palsy. Cardiovascular cause should be listed as a differential diagnosis of hoarseness and is incumbent upon the diagnostic physician to be familiar with the condition. A 56-year-old male presented to our emergency department with shortness of breath due to severe mitral regurgitation. Read More
J Cardiol Cases 2013 Jan 15;7(1):e21-e23. Epub 2012 Oct 15.
Department of Cardiology, Matsushita Memorial Hospital, Sotojima 5-55, Moriguchi, Osaka 570-8540, Japan.
Chordoma is a rare neoplasm of bone that develops from the remnants of the primitive notochord. We present a 78-year-old woman with metastatic chordoma to the left ventricle. She had been diagnosed with sacral chordoma 5 years earlier, and chordoma gradually spread to numerous muscles, the ankle joint of the left leg, bilateral lungs, and the brain, despite repeated surgical excisions and carbon heavy-ion radiotherapy. Read More
J Cardiol Cases 2013 Jan 5;7(1):e11-e14. Epub 2012 Oct 5.
Department of Cardiology, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan.
Although primary aldosteronism had been recognized to be a treatable type of hypertension, it was recently suggested to be associated with an increased risk of cardiovascular complications. Coronary artery aneurysm is a rare complication after drug-eluting stent (DES) implantation, and a giant coronary aneurysm is very rare. The present case is a 51-year-old, hypertensive patient with primary aldosteronism who developed myocardial infarction, a giant coronary aneurysm after DES implantation, and then cerebral hemorrhage. Read More
J Cardiol Cases 2012 Jun 11;5(3):e163-e165. Epub 2012 May 11.
Tokyo Heart Center, Department of Cardiovascular Surgery, Tokyo, Japan.
We present a case of a giant fenestration and a fibrous strand rupture of the aortic valve without massive regurgitation. A 56-year-old woman, was referred for coronary revascularization, had II-III degree aortic regurgitation without symptoms of heart failure. On the intraoperative direct view, the non coronary cusp (NCC) had the giant fenestration and the left coronary cusp (LCC) had the fibrous strand rupture. Read More
J Cardiol Cases 2012 Jun 12;5(3):e160-e162. Epub 2012 Jan 12.
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
We report an unusual case with giant left atrial thrombus which disappeared soon after starting anticoagulation without evidence of further systemic embolism. A 75-year-old female with non-valvular atrial fibrillation suddenly complained of pain of her right arm and left leg. Contrast-enhanced computed tomography showed occlusion of right brachial and left popliteal arteries. Read More
J Cardiol Cases 2012 Apr 2;5(2):e96-e99. Epub 2012 Mar 2.
Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Japan.
An asymptomatic 43-year-old woman visited our hospital for differential diagnosis of cardiac murmur. The transthoracic echocardiogram exhibited a dilated duct, which had turbulently accelerated color Doppler flow behind left ventricle. The coronary angiography (CAG) revealed a marked dilated left circumflex artery (LCX), which appeared to connect to coronary sinus (CS), indicating coronary artery fistula. Read More
J Cardiol Cases 2011 Oct 11;4(2):e76-e79. Epub 2011 Aug 11.
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Behçet's disease is a chronic, relapsing, multi-systemic inflammatory disorder characterized by recurrent orogenital aphthous ulcers, uveitis, and skin lesions. Vascular involvement affects the veins more commonly than the arteries of these patients. Arterial involvement may include aneurysm formation, occlusive disease, and stenosis, with the most common sites being the abdominal aorta and femoral and pulmonary arteries. Read More
J Cardiol Cases 2011 Apr 17;3(2):e86-e89. Epub 2011 Feb 17.
Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, 5-3-1 Chikami, Kumamoto 861-4193, Japan.
An 87-year-old woman who had metastatic lung cancer presented with intermittent chest discomfort. The emergent coronary angiogram showed a giant saddle thrombus at the left main coronary artery bifurcation without flow limitation. We performed thrombolysis with unfractionated heparin and warfarin under careful observation of the thrombus with a 320-row area detector computed tomography (ADCT). Read More
J Cardiol Cases 2010 Oct 5;2(2):e71-e73. Epub 2010 May 5.
Heart Center of Chonnam National University Hospital, Jaebongro 167, Donggu, Gwangju, Gwangju 501-757, Republic of Korea.
Coronary aneurysm is a vascular anomaly which can cause hemodynamic problems due to coronary steal phenomenon. We report the case of an asymptomatic 68-year-old woman with a large coronary aneurysm with fistula arising from the left main coronary artery. As a consequence of the longstanding volume overload, the coronary arteries were extremely dilated and drained through the coronary sinus into the right atrium. Read More
Cell Physiol Biochem 2018 11;51(5):2472-2483. Epub 2018 Dec 11.
Spine Tumor Center, Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Background/aims: Giant cell tumor of bone (GCTB), one of the most common primary bone tumors, leads to extensive bone destruction. However, the mechanisms underlying GCTB progression remain elusive and prognostic factors and treatment targets are required. In the current study, we explored the function of the chemokine family member CCL20 in GCTB progression. Read More
Hum Immunol 2018 Dec 8. Epub 2018 Dec 8.
Departmentof Medicina, Ciencias de la Salud, Universidad del Norte, Barranquilla, Colombia.
Wayu Amerindians live around Guajira Peninsula shared by Colombia and Venezuela. Wayu from Colombia South have been studied for their HLA profile and these data put in context with both genetic and cultural relatedness to Pacific Islanders. HLA-A*24 and HLA-B*35 (most likely HLA-A*24:02 and HLA-B*35:05) and HLA-DRB1*04:03 and HLA-DQB1*03:02 are shared both by Wayu and other Amerindians and Pacific Islanders in specific high frequency. Read More
Adv Mater 2018 Dec 9:e1801949. Epub 2018 Dec 9.
School of Materials Science and Engineering, State Key Lab of New Ceramics and Fine Processing, Tsinghua University, Beijing, 100084, China.
The electrocaloric effect (ECE) refers to reversible thermal changes of a polarizable material upon the application or removal of electric fields. Without a compressor or cooling agents, all-solid-state electrocaloric (EC) refrigeration systems are environmentally benign, highly compact, and of very high energy efficiency. Relaxor ferroelectric ceramics and polymers are promising candidates as EC materials. Read More
Rom J Morphol Embryol 2018 ;59(3):679-690
Discipline of Histology, Department of Morphological Sciences, "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania;
Giant cell granulomas in the oral cavity are reactive hyperplastic lesions that arise either peripherally in the mucoperiosteum or centrally in the bone. The peripheral giant cell granuloma (PGCG) is a benign lesion induced by local chronic irritation. It may develop at any age, and tends to be more frequent in females. Read More
Med Ultrason 2018 Dec;20(4):536-538
Department of Radiology, Interdisciplinary Ultrasound-Center Ludwig-Maximilians-University of Munich - Grosshadern Campus, Munich, Germany.
This case report relates the use of contrast-enhanced ultrasound (CEUS) for the assessment and treatment of a postinterventional cholecystitis, a rare but important complication after transcatheter arterial embolization of a giant hemangioma. Regarding the imaging diagnosis, hemangiomas have specific features allowing a fast recognition by all radiological modalities,and in recent years, especially by CEUS. Read More
Microbiol Resour Announc 2018 Sep 20;7(11). Epub 2018 Sep 20.
Department of Pathogenic Biology, School of Basic Medical Science, Chengdu Medical College, Chengdu, Sichuan, China.
Here, we report the complete genome sequence of Weissella cibaria M2, a potential probiotic strain isolated from the feces of a giant panda (Ailuropoda melanoleuca). The genome consists of one chromosome of 2.56 Mb and two plasmids. Read More
Ann Indian Acad Neurol 2018 Oct-Dec;21(4):304-308
Department of Pediatric Neurosciences, Bai Jerbai Wadia Hospital for Children, Mumbai, India.
Introduction: Giant axonal neuropathy (GAN) is an inherited neurodegenerative disorder caused by mutations in the GAN gene. It affects both the central and peripheral nervous systems. We discuss clinical, electrophysiological, radiological and genetic features in three new unrelated patients with GAN. Read More
Sci Data 2018 Dec 11;5:180283. Epub 2018 Dec 11.
Graduate School of Cancer Science and Policy, Cancer Biomedical Science, National Cancer Center, Gyeonggi-do, Republic of Korea.
Mutations of histone variant H3.3 are highly recurrent in childhood glioblastoma and in young adults with Giant Cell Tumor of the Bone (GCTB). The heterozygotic representation of the mutations in the tumors, and with potential histone H3 and H3. Read More
Eye (Lond) 2018 Dec 7. Epub 2018 Dec 7.
Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
J Neuroophthalmol 2018 Oct 23. Epub 2018 Oct 23.
Departments of Ophthalmology (MD, JW, CO), Neurology (MD, AEM), and Pathology (EL), Weill Cornell Medical College, New York, New York.
Background: To describe a case of optic neuropathy associated with intravascular lymphoma (IVL).
Methods: Case report and review of the literature.
Results: A case of asymmetric binocular vision loss is described, preceded by transient vision loss. Read More
Retin Cases Brief Rep 2018 Nov 28. Epub 2018 Nov 28.
Department of Ophthalmology, Ministry of Education, Key Laboratory of Vision Loss and Restoration, Peking University Third Hospital, Beijing, China.
Purpose: Optic disk astrocytoma is a rare variant of congenital hamartoma, which is usually associated with tuberous sclerosis complex. Generally, it is stationary but in rare cases, it can show progressive growth and cause severe local complications.
Methods: Clinical-pathologic correlation. Read More
Neurol Med Chir (Tokyo) 2018 Dec 7. Epub 2018 Dec 7.
Department of Neuroendovascular Therapy, Institute of Biomedical Research and Innovation.
Although the current standard treatment for unruptured aneurysms comprises surgical clipping or endovascular coiling, these techniques are not suitable for some cases, such as large, giant, and fusiform aneurysms. Endovascular parent artery occlusion (PAO), which includes internal trapping and proximal occlusion, is a well-established alternative treatment for such cases. Here, we retrospectively reviewed PAO cases from the Japanese Registry of Neuroendovascular Therapy 3, a nation-wide survey of all neuroendovascular therapy cases between 2010 and 2014. Read More
Neurology 2018 Dec;91(24):1107-1108
From the Departments of Neurology (G.T., P.P., M.C., A.D.) and Neuroradiology (C.D.), CHU Montpellier, France.
Int J Biol Macromol 2018 Dec 7. Epub 2018 Dec 7.
College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China. Electronic address:
Japalura flaviceps is a subarboreal species, which is endemically distributed in China. Here, we determined the complete mitogenome of J. flaviceps. Read More
World Neurosurg 2018 Dec 6. Epub 2018 Dec 6.
Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, 60612. Electronic address:
Flow diversion technology has revolutionized the treatment of complex anterior circulation cerebral aneurysms. However, vessel tortuosity and atherosclerotic disease may hamper the standard transfemoral access used in these procedures. Percutaneous direct carotid puncture is a viable alternative, but adequate carotid closure must be achieved. Read More
Neurobiol Dis 2018 Dec 7. Epub 2018 Dec 7.
Division of Neuroscience, Biomedical Sciences Research Centre "Alexander Fleming", 34 Fleming str, Vari 16672, Greece. Electronic address:
Accumulation of normal or mutant human Tau isoforms in Central Nervous System (CNS) neurons of vertebrate and invertebrate models underlies pathologies ranging from behavioral deficits to neurodegeneration that broadly recapitulate human Tauopathies. Although some functional differences have begun to emerge, it is still largely unclear whether normal and mutant Tau isoforms induce differential effects on the synaptic physiology of CNS neurons. We use the oligosynaptic Giant Fiber System in the adult Drosophila CNS to address this question and reveal that 3R and 4R isoforms affect distinct synaptic parameters. Read More
Biochim Biophys Acta Biomembr 2018 Dec 5;1861(2):478-485. Epub 2018 Dec 5.
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, United States of America. Electronic address:
Chemically simplified lipid mixtures are used here as models of the cell plasma membrane exoplasmic leaflet. In such models, phase separation and morphology transitions controlled by line tension in the liquid-disordered (Ld) + liquid-ordered (Lo) coexistence regime have been described . Here, we study two four-component lipid mixtures at different cholesterol fractions: brain sphingomyelin (BSM) or 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)/1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)/cholesterol (Chol). Read More
J Clin Neurosci 2018 Oct 24. Epub 2018 Oct 24.
Department of Neurosurgery, The Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Surgery, The University of Melbourne, Parkville, Victoria, Australia.
Tuberous sclerosis complex (TSC) is a multisystem, autosomal dominant disorder with a wide clinical spectrum. The most common brain tumor associated with TSC is the low grade subependymal giant cell astrocytoma. Reports of high grade primary brain tumors in patients with TSC are rare. Read More
Best Pract Res Clin Rheumatol 2018 04 2;32(2):271-294. Epub 2018 Nov 2.
Department of Rheumatology, Hospital of Bruneck, Bruneck, Italy; Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria.
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and giant cell arteritis (GCA) are the most common primary systemic vasculitides of the adult population, while polymyalgia rheumatica (PMR) is a clinical syndrome often associated with GCA. Incidence and prevalence rates of AAV have been increasing in the last decades, whereas those of GCA and PMR have remained stable. The mutual interplay between environmental and genetic risk factors leading to the development of these diseases has been further analyzed in the last years. Read More
Biophys J 2018 Nov 16. Epub 2018 Nov 16.
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio. Electronic address:
The cadherin superfamily of proteins is defined by the presence of extracellular cadherin (EC) "repeats" that engage in protein-protein interactions to mediate cell-cell adhesion, cell signaling, and mechanotransduction. The extracellular domains of nonclassical cadherins often have a large number of EC repeats along with other subdomains of various folds. Protocadherin-15 (PCDH15), a protein component of the inner-ear tip link filament essential for mechanotransduction, has 11 EC repeats and a membrane adjacent domain (MAD12) of atypical fold. Read More
Can J Cardiol 2018 Dec 24;34(12):1688.e5-1688.e7. Epub 2018 Aug 24.
Section of Cardiology, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:
We describe a case of a 54-year-old woman who had a right cardiac mass found on coronary angiography. Echocardiography, computed tomography, and cardiac magnetic resonance imaging characterized it as a thrombosed giant right coronary artery aneurysm. This was confirmed on pathology. Read More