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    130 results match your criteria Giant Condylomata Acuminata of Buschke and Lowenstein

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    A case of reccuring giant condyloma of vulva in infant without sexual abuse successfully treated with electrocoagulation in Benin.
    Pan Afr Med J 2017 30;27:159. Epub 2017 Jun 30.
    Dermatology-Venereology, Faculty of Health, Cotonou, University of Abomey-Calavi, R. Benin.
    We report here a case of giant vulval condyloma in a two-year-old infant infected by her "baby sitter" without sexual abuse. Treated by surgical excision coupled with electrocoagulation, it was noted a rapid recurrence two weeks after treatment requiring a second electrocoagulation session. More than a year later, no lesion was noted, thus demonstrating therapeutic success. Read More

    [Buschke-Lowenstein tumors].
    Hautarzt 2017 Mar;68(3):199-203
    Hautklinik, Universitätsklinikum der RWTH-Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
    Background: A giant condyloma acuminatum which shows destructive growth but lacking invasion is designated as a Buschke-Lowenstein tumor (BLT).

    Objectives: Classification of the BLT and therapeutic guidelines are provided.

    Materials And Methods: A MEDLINE literature search from 2006-2016 was performed. Read More

    Anal verrucous carcinoma is not related to infection with human papillomaviruses and should be distinguished from giant condyloma (Buschke-Löwenstein tumour).
    Histopathology 2017 May 24;70(6):938-945. Epub 2017 Feb 24.
    Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
    Aims: Verrucous carcinoma (VC) is a variant of well-differentiated squamous cell carcinoma and in the anal region is regarded as synonymous with giant condyloma (Buschke-Löwenstein tumour) (BLT). Aetiology, diagnostic criteria and clinical behaviour of both lesions are controversial. Recent studies suggest that VC at other sites is not associated with human papillomaviruses (HPV). Read More

    Successful improvement of Buschke-Löwenstein tumour in an HIV-infected patient with antiretroviral therapy alone.
    BMJ Case Rep 2016 Nov 21;2016. Epub 2016 Nov 21.
    Hopitaux Universitaires Henri Mondor, Creteil, France.
    Buschke-Löwenstein tumour (BLT), also defined as giant condyloma acuminatum, is a rare exophytic tumour affecting the anogenital and perianal regions associated with human papillomavirus (HPV) infections, with a potential of malignant transformation and which is at a greater risk in T-cell mediated immunodeficient patients. Different therapeutic options, alone or in combination, have been reported for the treatment of BLT including local therapy but wide surgical local excision is however recommended as the most important therapeutic intervention. We report a case of a HIV-infected man who developed a voluminous pelvic BLT which disappeared progressively under antiretroviral therapy with no additional treatment, contemporary to an improvement of his immunity, highlighting the possible spontaneous reversibility of HPV-induced tumours in treated HIV infection. Read More

    Giant Perineal Condyloma Acuminatum (Buschke-Lowenstein Tumour): A Case Report.
    Chirurgia (Bucur) 2016 Sept-Oct;111(5):435-438
    The giant condyloma acuminatum, also known as Buschke- Lowenstein tumor (BLT), is a rare sexually-transmitted disease. Moreover, the condyloma acuminatum produced by Human Papilloma Virus (HPV) infection becomes one the most common sexually-transmitted infection which affects the perineal region. Under such situations, the first therapeutic option is surgical excision. Read More

    Invasive squamous cell carcinoma originating from a giant penile condyloma.
    Int J STD AIDS 2017 May 23;28(6):619-622. Epub 2016 Feb 23.
    3 Department of Pathology, Izmir Training and Research Hospital, Izmir, Turkey.
    In this case study, we present an unusual case with squamous cell carcinoma originating from a giant condyloma acuminata completely surrounding the penis. A 57-year-old circumcised heterosexual male patient presented with a penile lesion existing for 20 years. Incisional biopsy revealed acanthosis of the squamous epithelium. Read More

    Rapidly Invasive Buschke-Löwenstein Tumor Associated With Human Papillomavirus Types 6 and 52.
    Sex Transm Dis 2015 Oct;42(10):547-8
    From the *Dermatology and Venereology Unit, Department of Pathophysiology and Organ Transplantation, University of Milan Medical School, Milan, Italy; †Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; and ‡Divisions of Urology and §Pathology, Fondazione IRCCS, Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
    Buschke-Löwenstein tumor, or giant condyloma acuminatum, represents a rare, sexually transmitted disorder, with a slow evolution and the tendency to infiltrate in the adjacent tissues associated with human papillomavirus (HPV). This article reports the first case of male Buschke-Löwenstein tumor associated with HPV6 and HPV52. Read More

    Giant Condyloma Acuminatum of Vulva Frustrating Treatment Challenge.
    World J Plast Surg 2015 Jul;4(2):159-62
    Department of Plastic Surgery, Shahid Beheshti University of Medical Sciences, Modaress Hospital, Tehran, Iran.
    Giant condylomata are not usually seen nowadays in developed nations, but such cases are still seen in the under-resourced countries. Condylomata acuminata are commonly transmitted through sexual intercourse. Generally diagnosed based on their appearance. Read More

    Electrocautery resection, shaving with a scalpel, and podophyllin: a combination therapy for giant condyloma acuminatum.
    World J Mens Health 2015 Apr 23;33(1):39-41. Epub 2015 Apr 23.
    Department of Urology, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.
    Giant condyloma acuminatum (also known as Buschke-Löwenstein tumor) is a rare disease, for which the treatment of choice is still controversial. In the case described in this report, we used a combination of electrocautery and a surgical scalpel to resect a huge genital wart, followed by long-term local treatment with podophyllin. This procedure was relatively fast, easy to perform, involved minimal bleeding, and did not result in any complications. Read More

    Buschke - Loewenstein tumor resection with simultaneous reconstruction of extensive tissue losses: case report.
    BMC Surg 2015 Apr 10;15:41. Epub 2015 Apr 10.
    The Chair and Department of General, Endocrine and Gastroenterological Oncology Surgery, Karol Marcinkowski University of Medical Sciences in Poznań, ul. Przybyszewskiego 49, 60-355, Poznań, Poland.
    Background: Giant condyloma acuminatum or Buschke - Loewenstein tumor is a very rare disease usually located in the genital, anorectal, and perianal regions. It is locally invasive but in mostly cases displays a benign cytology on preoperative tissue sampling. Because of its low incidence little is known about treatment outcomes. Read More

    Circumferential anal giant condyloma acuminatum: a new surgical approach.
    Dis Colon Rectum 2015 Apr;58(4):e49-52
    Istituti Clinici Zucchi, Università degli Studi Milano-Bicocca, Milan, Italy.
    Introduction: Perianal giant condyloma acuminatum is a rare clinical condition related to human papillomavirus infection and characterized by a circumferential, exophytic, cauliflower-like mass with an irregular warty surface localized in the anal region.

    Technique: A circular incision with a diathermocoagulator was performed on macroscopically healthy skin, 1 cm from the margin of the lesion. The dermis was divided from the subcutaneous tissue. Read More

    Giant condylomata acuminata of Buschke and Lowenstein: A peristomal variant.
    Int J Surg Case Rep 2014 30;5(12):1014-7. Epub 2014 Oct 30.
    York Hospital, York, UK. Electronic address:
    Introduction: Giant condylomata acuminata (GCA) is a rare, locally invasive tumour that may undergo malignant transformation. It was first described a HPV-induced penile tumour which clinically resembled both a squamous cell carcinoma and condyloma acuminatum, often arising from a pre-existing warty lesion. We describe a case of peri-stomal GCA transformation into invasive squamous cell carcinoma (SCC), which is, to our knowledge, the first report of this in the literature. Read More

    Periurethral and vulval condylomata acuminata: an unusual juvenile venereal disease in a 3-year-old girl.
    BMJ Case Rep 2014 Sep 8;2014. Epub 2014 Sep 8.
    Department of Paediatric Dermatology and Venereal diseases, UCLH and GOSH, London, UK.
    We present a case of giant condyloma acuminatum (CA) in a 3-year-old girl with rapidly growing vulval and periurethral lesions, which was investigated thoroughly and successfully treated with excision biopsy. Genital warts in the form of giant alarming vestibular, vulval and periurethral lesions of CA are very rare in children. There is need for a multidisciplinary approach with potential sociomedicolegal implications. Read More

    Giant condyloma acuminatum - Buschke-Lowenstein disease - a literature review.
    Chirurgia (Bucur) 2014 Jul-Aug;109(4):445-50
    Aim: Buschke-Lowenstein disease or giant condyloma acuminatum represents a rare, sexually transmitted disorder, with a slow evolution and the tendency to infiltrate in the adjacent tissues; untreated, the outcome is unfavorable. The hallmark is the development of one or various prominent-sized vegetant tumors that usually ulcerate.

    Material And Methods: The present article summarizes both the etiopathogenic features and the current approach of treatment management. Read More

    Psychotic depression due to giant condyloma Buschke-Löwenstein tumors.
    Rom J Morphol Embryol 2014 ;55(1):189-95
    Department of Psychiatry, "Carol Davila" University of Medicine and Pharmacy, 1st Department of Psychiatry, "Prof. Dr. Alexandru Obregia" Clinical Psychiatry Hospital, Bucharest, Romania;
    Unlabelled: A 63-year-old patient, with no psychiatric history, was admitted in the psychiatric department with depressed mood, loss of interest in activities, apathy, insomnia, attention deficit, irritability, social withdrawal, prejudice and abandon delusions. Cerebral computed tomography (CT) scan was normal but the general physical examination revealed a voluminous tumor in the inguino-pubic-ano-genital area measuring 350/80/40 mm, which appeared 15 years ago and grew gradually leading to local rickety hygiene and also to depression, especially in the last time period when the tumor grew faster. The DSM-IV-TR diagnostic was affective disorder due to general medical condition. Read More

    [A woman with a growing mass near the anus].
    Ned Tijdschr Geneeskd 2013 ;157(41):A6617
    Medisch Centrum Alkmaar, afd. Heelkunde, Alkmaar.
    A 58-year-old woman visited the surgical outpatient clinic because of a mass near the anus that had existed for years and had now grown to a size that made sitting impossible. With histological examination of the 6 x 10 cm exofytic, condylomatic mass, the diagnosis 'giant condyloma acuminatum' was made. Radical excision was performed, the patient recovered well. Read More

    Giant condyloma acuminata of Buschke-Lowenstein: successful treatment mainly by an innovative surgical method.
    Dermatol Ther 2013 Sep-Oct;26(5):411-4. Epub 2013 Mar 13.
    Department of Dermatology and Venereology, The 2nd Affiliated Hospital of Kunming Medical University, Kunming, China.
    Many remedies can be applied to condyloma acuminatum. However, it is the most difficult to treat giant condyloma acuminatum because of bleeding, recurrence, intolerance of patients, etc. After careful physical examination, the present authors found the giant tumor was composed of many smaller cauliflower-like warts with long and thin pedicles. Read More

    Giant condyloma of the cervix: an uncommon entity associated with low-risk human papilloma virus infection.
    Am J Surg Pathol 2013 Feb;37(2):300-4
    Department of Pathology, Women's and Perinatal Pathology Division, Brigham and Women's Hospital-Harvard Medical School, Boston, MA 02115, USA.
    "Giant Condylomas" of the cervix are very uncommon, and have not been fully characterized in the English literature. We report 4 cases of cervical giant condyloma seen in our practice. Patients were predominantly young and presented with a cervical lesion producing bleeding or a mass effect. Read More

    Buschke-Lowenstein Tumor.
    Acta Med Port 2012 Sep-Oct;25(5):345-7. Epub 2012 Nov 12.
    Serviço de Ginecologia, Maternidade Júlio Dinis, Centro Hospitalar do Porto, Porto, Portugal.
    Introduction: Giant condyloma acuminatum belongs to a spectrum of diseases with malignant degeneration. Clinically, it presents as exophytic, fungating masses, sometimes with a cauliflower-like morphology.

    Case Presentation: We present a case of a 32-year-old female patient with a 180x95x80mm exophytic mass of the vulvar region suggestive of Buschke-Lowenstein Tumour. Read More

    Giant condyloma acuminatum quickly growing: case report.
    G Chir 2012 Oct;33(10):327-30
    Department of Surgery and Oncology Sciences, General Surgery Unit, University of Study of Palermo, Italy.
    Background: Giant Condyloma Acuminatum (GCA) is a rare, slow growing, large cauliflower tumor of the penile foreskin and perianal region with benign histologic appearance but high propensity for local invasion and recurrences. GCA is associated with Human Papilloma Virus (HPV) types 6 and 11 and it also has considerable risk of neoplastic transformation into fully invasive squamous cell carcinoma into about 5 years.

    Objective: Because of the rarity of perianal GCA, to date there is no general agreement on the best method for treatment. Read More

    Giant condylomata (Buschke-Löwenstein tumours): our case load in surgical treatment and review of the current therapies.
    Eur Rev Med Pharmacol Sci 2012 Jun;16(6):747-51
    Chirurgia Plastica e Ricostruttiva, Dipartimento di Discipline Chirurgiche ed Oncologiche, Università degli Studi di Palermo, Italy.
    Background: Buschke-Löwenstein tumour (BLT) or giant condyloma is a verrucous infiltrating lesion, due to a sexually transmitted virus infection, human papilloma virus subtypes 6 and 11. Poor hygiene, promiscuity, chronic irritation and cellular immunocompromised states are often implicated in its genesis. Typical treatment of giant condyloma includes imiquimod cream, podophillin resin, cryotherapy, laser surgery, tangential shave excision with electrocautery. Read More

    Successful treatment of giant condyloma acuminatum with combination retinoid and interferon-γ therapy.
    Int J STD AIDS 2012 Jun;23(6):445-7
    Department of Dermatology and Venereology, First Hospital of Jilin University, 71 Xinmin Street, Changchun, Jilin, China.
    Giant condyloma acuminatum, or Buschke-Löwenstein tumour, is a unique variant of anogenital warts. It is characterized by locally aggressive behaviour but rarely metastasizes. Many treatment strategies such as radical surgery, radiation and chemotherapy have been used to treat it but their efficacy is often poor and the recurrence rates are high. Read More

    Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma.
    Mod Pathol 2012 Oct 8;25(10):1354-63. Epub 2012 Jun 8.
    Unit of Molecular Pathology, Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
    The role of human papillomavirus (HPV) infections in the development of verrucous carcinoma, a well-differentiated variant of squamous cell carcinoma with difficult differential diagnosis, is controversial in the literature. In this study, we analysed verrucous carcinoma from different origins for the presence and activity of a broad spectrum of HPV types, and carefully reviewed the histopathological features. A random series of 27 formalin-fixed, paraffin-embedded specimens of verrucous carcinoma was taken, representing the head and neck region (n=6), anogenital area (n=16) and extragenital skin region (n=5). Read More

    [Perianal Buschke-Löwenstein tumour].
    Ugeskr Laeger 2012 Jun;174(23):1616-7
    Kirurgisk Gastroenterologisk Afdeling A, Aarhus Universitetshospital, Aalborg Sygehus, Hobrovej 18-22, 9000 Aalborg, Denmark.
    The Buschke-Löwenstein tumour is an extremely rare, slow-growing cauliflower-like mass, also known as giant condyloma acuminantum or verrucous carcinoma. It is located in the anogenital region and is characterized by its large size, locally destructive behaviour and a high recurrence rate. It has not the potentiel to metastasize but malignant transformation can occur. Read More

    Therapeutic combination of radiofrequency surgical dissection and oral acitretin in the management of perianal Buschke-Lowenstein tumour: a case report.
    Int J STD AIDS 2012 May;23(5):362-4
    Gastroenterology Department of Army Veterans General Hospital of Athens, Athens, Greece.
    Giant condyloma acuminatum (GCA), or Buschke-Löwenstein tumour (BLT), is a rare large tumour of the anogenital area. It is caused by human papillomavirus genotypes 6 and 11, and it is characterized by aggressive local invasion and frequent recurrences after treatment. Treatment of choice is radical excision, although chemotherapy and radiation are also used in special cases. Read More

    Buschke -Loewenstein tumor: identification of HPV type 6 and 11.
    An Bras Dermatol 2012 Jan-Feb;87(1):131-4
    Dermatology and Skin Cancer Center, AC Camargo Hospital, São Paulo, SP, Brazil.
    The authors report a case of exuberant giant condyloma acuminatum of Buschke-Loewenstein in a male patient, slow-growing, progressive and with locally destructive behavior in the inguinal, body of the penis, scrotum, perineal and perianal regions. After surgery he showed no signs of recurrence in 20 months of follow-up. The identification of HPV types 6 and 11 was performed using in situ hybridization. Read More

    Management of giant anal condyloma by wide local excision and anoplasty.
    Colorectal Dis 2012 Nov;14(11):1394-7
    Department of Surgery, Hospital Arnau de Vilanova of Valencia, Valencia, Spain.
    Aim: Treatment of giant condyloma acuminatum, is controversial, especially in human immunodeficiency virus (HIV)-positive patients, owing to concern over wound healing, complications, risk of progression to carcinoma and a high recurrence rate. The aim of this study was to evaluate the outcome after extensive local excision with V-Y anoplasty.

    Method: Nine patients were identified from a prospective database, six of whom were HIV positive. Read More

    Scrotal Buschke-Lowenstein tumor in an AIDS patient.
    Sex Transm Dis 2012 Mar;39(3):236-7
    Department of Dermatology, The University of Texas Heath Science Center at Houston, Houston, TX 77030, USA.
    Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor, is a slow-growing neoplasm notable for its size and presentation in the anogenital region. A viral etiology suggests it should be more common in the immunocompromised; however, few reports exist in the literature. The evaluation, treatment, and role of preventative measures are reviewed. Read More

    Giant condyloma acuminatum of the anorectum: successful radical surgery with anal reconstruction.
    Tumori 2011 Nov-Dec;97(6):805-7
    Division of General Surgery B, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Venezian 1, Milan, Italy.
    Buschke-Löwenstein tumor, or giant condyloma acuminatum, is a relatively uncommon lesion of the anus with aggressive local invasive behavior which may present as a large warty tumor of the genital region with expansive and destructive growth. Many sporadic reports have been published suggesting various therapeutic strategies. We report a case of Buschke-Löwenstein tumor treated with conservative surgery followed by reconstructive procedures without a loop colostomy Read More

    [Buschke-Lowenstein tumor associated with scrotal melanoma. A case report].
    Prog Urol 2012 Jan 20;22(1):70-2. Epub 2011 Apr 20.
    Service d'anatomie et cytologie pathologique, CHU Hassan II, Fès, Maroc.
    Buschke-Lowenstein tumour (BLT) is a giant condyloma acumina, which is rare entity and represents only 1% of all populace. It is a rare viral disease, essentially transmitted by sexual intercourse, characterized by a potential for malignant transformation, invasion and recurrence after treatment. We report a case of BLT associated with perinea-scrotal melanoma. Read More

    [Buschke-Lowenstein Tumor associated to nasopharyngeal condillomatosis].
    Rev Gastroenterol Mex 2011 Jul-Sep;76(3):275-8
    Cirugía General y del Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid, España.
    Giant Acuminata Condyloma or Buschke-Lowenstein Tumor (BLT) is a rare disease characterized typically by its perineal location, local aggressiveness and its cauliflower-like aspect. BLT is associated with Human Papilloma Virus (HPV) infection. Because malignant transformation of BLT is high, radical local excision and histopathological examination are needed. Read More

    Perianal giant condyloma acuminatum (Buschke-Löwenstein tumor). Case report and review of the literature.
    Chirurgia (Bucur) 2011 Jul-Aug;106(4):535-9
    "Vasile Goldiş" Western University Arad, Department of Surgery, Romania.
    Unlabelled: Giant condyloma acuminatum, also known as Buschke-Löwenstein tumor (BLT) is a very rare sexually transmitted disease that affects the ano-genital region. BLT is a slow growing cauliflower-like tumor, but unlike simple condyloma, it is locally aggressive and destructive, malignant transformation occuring in 40-60% of cases. We present a case of perianal carcinomatous BLT and discuss some controversies about the nature and treatment of this disease. Read More

    Wilhelm Fabry's 1614 report on a giant condyloma of the penis.
    Br J Dermatol 2012 Feb 14;166(2):247-51. Epub 2011 Dec 14.
    Institute for the History of Medicine and Medical Ethics, University of Cologne, Joseph-Stelzmann-Strasse 20, D-50931 Cologne, Germany.
    For many years it has been the work of Buschke and Löwenstein that has justified calling the exophytic, locally destructive tumour of the anogenital mucosal surface 'giant condyloma of Buschke and Löwenstein' or GCBL. In order to investigate the early history of this rare disease we examined the writings of the barber-surgeon Wilhelm Fabry (1560-1634) who had a serious interest in dermatological disorders and their treatment. We analysed Fabry's 600 Latin case reports and identified the case of a 'monstrous penile tumour'. Read More

    [Surgical treatment of a perianal giant condyloma acuminata in a HIV patient].
    Rev Gastroenterol Mex 2011 Apr-Jun;76(2):178-81
    Departamento de Dermatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán y Universidad Nacional Autónoma de México, México, D.F.
    Buschke-Löwenstein tumor is a slowly growing neoplasm with high potential of local invasion. We described a 29 year-old female with acquired immunodeficiency syndrome who was surgically treated for a Buschke- Löwenstein tumor with a wide local excision, bilateral gluteal flaps and loop ileostomy. At 12 months follow-up, there was no evidence of recurrence. Read More

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