84,403 results match your criteria Giant Cell Tumor Imaging


A giant sacrococcygeal teratoma in adult female: A case report.

Int J Surg Case Rep 2018 Nov 22;54:47-50. Epub 2018 Nov 22.

Department of General Surgery, King Abdulla University Hospital, Faculty of Medicine, Jordan University of Science and Technology, P.O. Box (3030), Irbid, 22110, Jordan. Electronic address:

Introduction: Sacrococcygealteratoma is very rare in adults with only few cases reported in literature. It is a slow growing benign cystic tumor with 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. When grows caudally, it causes discomfort, skin excoriation and cosmetic disfigurement. Read More

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November 2018
3 Reads

PEG-grafted phospholipids in vesicles: Effect of PEG chain length and concentration on mechanical properties.

Chem Phys Lipids 2018 Dec 3. Epub 2018 Dec 3.

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India. Electronic address:

Incorporation of low molecular weight poly-ethylene glycol (PEG) - grafted phospholipids in vesicle bilayers is known to increase the circulation time of liposomal drug delivery vehicles. Mechanical properties of giant unilamellar DPPC vesicles containing varying concentrations of DSPE-PEG (PEG MW: 550, 1000 and 2000) were measured by micropipette aspiration assay or osmotic swelling. While the area compressibility modulus did not change significantly, the bending modulus and water permeability of the bilayer was found to increase with increasing mole fraction of DSPE-PEG. Read More

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December 2018

A gradient-based, GPU-accelerated, high-precision contour-segmentation algorithm with application to cell membrane fluctuation spectroscopy.

PLoS One 2018 6;13(12):e0207376. Epub 2018 Dec 6.

Mechanics of Biological Membranes and Biorheology, Dpto. Química Física I, Universidad Complutense, Madrid, Spain.

We present a novel intensity-gradient based algorithm specifically designed for nanometer-segmentation of cell membrane contours obtained with high-resolution optical microscopy combined with high-velocity digital imaging. The algorithm relies on the image oversampling performance and computational power of graphical processing units (GPUs). Both, synthetic and experimental data are used to quantify the sub-pixel precision of the algorithm, whose analytic performance results comparatively higher than in previous methods. Read More

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December 2018

GLUT3 expression in cystic change induced by hypoxia in pituitary adenomas.

Endocr Connect 2018 Dec 1. Epub 2018 Dec 1.

S Wang, Neurosurgery, Fuzhou General Hospital, Fuzhou, China., Fuzhou, China.

Tumor cells require large amounts of energy to sustain growth. Through the mediated transport of glucose transporters, the uptake and utilization of glucose by tumor cells are significantly enhanced in the hypoxic microenvironment. Pituitary adenomas are benign tumors with high energy metabolisms. Read More

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December 2018
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Transient Q-waves in an infant with asymptomatic myocardial infarction due to Kawasaki disease.

Cardiol Young 2018 Dec 6:1-4. Epub 2018 Dec 6.

Department of Pediatrics,Shinshu University School of Medicine,Asahi 3-1-1, Matsumoto,Japan.

Giant coronary artery aneurysms are a complication of Kawasaki disease and can be fatal if associated with thrombosis. We describe the clinical outcome of a boy with Kawasaki disease who exhibited "supergiant" coronary artery aneurysms at the age of 14 months and, despite treatment with anticoagulant and antiplatelet medication, developed a left coronary artery thrombosis and presented following a myocardial infarction at 2 years old. Although his symptoms were minimal, the myocardial infarction was identified by abnormal Q-waves and giant negative T-waves in precordial leads of routine electrocardiography. Read More

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December 2018

Giant Cell Arteritis Presenting as an Ischaemic Upper Limb

Ir Med J 2018 08 13;111(7):791. Epub 2018 Aug 13.

Department of Rheumatology, Mercy University Hospital, Cork, Ireland

Aim To present an interesting case of giant cell arteritis presenting as ischaemic upper limb. Methods Data was collected from the patient’s chart and from radiology and laboratory systems in our institution. Results The patient had a temporal artery biopsy confirming the diagnosis of temporal arteritis. Read More

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Pleural anthracosis presenting with massive effusion: a rare entity.

Respirol Case Rep 2019 Feb 28;7(2):e00390. Epub 2018 Nov 28.

Respiratory Department Universiti Kebangsaan Malaysia Medical Centre Kuala Lumpur Malaysia.

Pleural anthracosis is rare and, in most cases, is diagnosed incidentally or at autopsy. We report a 67-year-old man with pleural anthracosis. He was initially referred for possible tuberculous pleural effusion and had recurrent admissions for symptomatic pleural effusion, which increased with each subsequent episode. Read More

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February 2019

Giant Left-Sided Amyand's Hernia: A Challenging Procedure in a Rural Hospital.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):646-652. Epub 2018 Nov 14.

Surgery Department, Bengkayang District General Hospital, Bengkayang, Indonesia.

The finding of a vermiform appendix in the case of an inguinal hernia that extends below the midpoint of the inner thigh when the patient is in a standing position is defined as giant left-sided Amyand's hernia. It is a very rare case and significantly challenging in terms of preoperative diagnosis and surgical management. Here we present our experience with a case of a giant left-sided Amyand's hernia that was followed up for 2 months. Read More

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November 2018

Giant prolactinoma, germline BRCA1 mutation, and depression: a case report.

J Med Case Rep 2018 Dec 6;12(1):360. Epub 2018 Dec 6.

Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, E.P.E., Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.

Background: Giant prolactinomas are very rare pituitary tumors that may exhibit an aggressive behavior and present with a life-threatening condition.

Case Presentation: A 25-year-old white woman was admitted to our hospital with a headache, psychomotor retardation, reduced vision, and loss of autonomy in daily activities. Her past medical history was significant for having oligomenorrhea and a depressive syndrome since her mother's death. Read More

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December 2018
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Microfluidic Deformability Study of an Innovative Blood Analogue Fluid Based on Giant Unilamellar Vesicles.

J Funct Biomater 2018 Dec 4;9(4). Epub 2018 Dec 4.

MEtRICs, Mechanical Engineering Department, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.

Blood analogues have long been a topic of interest in biofluid mechanics due to the safety and ethical issues involved in the collection and handling of blood samples. Although the current blood analogue fluids can adequately mimic the rheological properties of blood from a macroscopic point of view, at the microscopic level blood analogues need further development and improvement. In this work, an innovative blood analogue containing giant unilamellar vesicles (GUVs) was developed to mimic the flow behavior of red blood cells (RBCs). Read More

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December 2018
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Conductivity Tensor Imaging of In Vivo Human Brain and Experimental Validation using Giant Vesicle Suspension.

IEEE Trans Med Imaging 2018 Dec 3. Epub 2018 Dec 3.

Human brain mapping of low-frequency electrical conductivity tensors can realize patient-specific volume conductor models for neuroimaging and electrical stimulation. We report experimental validation and in vivo human experiments of a new electrodeless conductivity tensor imaging (CTI) method. From CTI imaging of a giant vesicle suspension using a 9. Read More

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December 2018

ICTV virus taxonomy profile: Sarthroviridae.

J Gen Virol 2018 Dec;99(12):1563-1564

5​Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968, USA.

The family Sarthroviridae includes a single genus, Macronovirus, which in turn includes a single species, Macrobrachium satellite virus 1. Members of this species, named extra small virus, are satellite viruses of Macrobrachium rosenbergii nodavirus, an unclassified virus related to members of the family Nodaviridae. Both viruses have isometric, spherical virions, infect giant freshwater prawns and together cause white tail disease, which is responsible for mass mortalities and severe economic losses in hatcheries and farms. Read More

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December 2018

The relevance of high-intensity zones in degenerative disc disease.

Int Orthop 2018 Nov 30. Epub 2018 Nov 30.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Queen Mary Hospital, 5/F Professorial Block, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China.

Purpose: The purpose of this study was to review the current understanding of high-intensity zones (HIZ) in the lumbar spine with particular attention to its imaging phenotype and clinical relevance.

Methods: A review was conducted of studies related to HIZ. Particular attention was made to imaging phenotypes and classification, and its relationship with discogenic low back pain (LBP). Read More

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November 2018
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A giant trichobezoar extracted by laparoscopic and endoscopic cooperative surgery (LECS).

Endosc Int Open 2018 Dec 29;6(12):E1413-E1416. Epub 2018 Nov 29.

Department of Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.

A gastric bezoar is a mass that forms in the stomach. A giant gastric bezoar is particularly difficult to treat medically, and surgical therapy is selected. We describe our experience with a patient who had a giant gastric trichobezoar that was extracted by laparoscopic and endoscopic cooperative surgery (LECS) in accordance with the principles of LECS. Read More

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December 2018
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A giant splenic hamartoma associated with hematologic disorders: A case report.

Ann Med Surg (Lond) 2018 Dec 16;36:199-202. Epub 2018 Nov 16.

Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Dr. Ignacio Morones Prieto O 3000, Monterrey, 64710, Mexico.

Introduction: Splenic hamartoma is a primary benign tumor of the spleen, with approximately 150 cases documented in the literature to date, with only a few cases associated with symptoms and hematologic disorders.

Presentation Of Case: A 49-year-old female with no past medical history, presented to the emergency department complaining of a three-month history of intermittent abdominal pain and 12 kg of weight loss. Physical examination revealed abdominal distension and a big palpable and painless mass on the left side of her abdomen measuring 14 cm. Read More

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December 2018

Giant simple biliary cyst infection treated with minimally invasive percutaneous drainage.

World J Nucl Med 2018 Oct-Dec;17(4):293-295

Department of Interventional Radiology, Hospital Israelita Albert Einstein, São Paulo, Brazil.

We describe a minimally invasive alternative approach in a patient with infected hepatic cyst to stabilize the patient before definitive surgery. A 58-year-old man presented with fever and hypotension after 2 weeks of asthenia, chills, weight loss, slight abdominal pain, and a previous asymptomatic simple hepatic cyst. On ultrasound, a giant heterogeneous hepatic cyst with thick wall was noted. Read More

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December 2018
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Large drusen in long-standing retinal detachment.

Oman J Ophthalmol 2018 Sep-Dec;11(3):272-273

Department of Ocular Pathology and Uveitis, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Drusen are seen as an end result of various biochemical insults to the retina and have been described in various clinical settings. We would like to report the histopathology of a case of large drusen, seen associated with chronic retinal detachment in a case of childhood trauma, where the eye was eviscerated for other reasons. Read More

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December 2018

Giant congenital facial melanocytic nevus.

Oman J Ophthalmol 2018 Sep-Dec;11(3):265-266

Dr. R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Giant Congenital Melanocytic Nevus (GCMNs) is mostly reported in area of trunk followed by limbs and head. Their incidence is <1:20,000 newborns It derives attention due to its association with malignant melanoma.The risk of developing malignant melanoma is between 5 to 10%. Read More

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December 2018

Defining giant mandibular ameloblastomas - Is a separate clinical sub-entity warranted?

Indian J Plast Surg 2018 May-Aug;51(2):208-215

Department of Plastic and Reconstructive Surgery, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

Context: The term giant mandibular ameloblastoma (GMAs) while being in popular usage in the medical literature remains largely equivocal. Although a few authors have in the past attempted to ascribe definite criteria to this entity, these are by and large arbitrary and without any benefit in decision-making or contributing to its management.

Aims: The aim of this study is to propose a set of objective criteria for GMAs that can be clinically correlated and thereby aid in the management of this entity. Read More

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December 2018

Accumulation of Transposable Elements in Autosomes and Giant Sex Chromosomes of Omophoita (Chrysomelidae: Alticinae).

Cytogenet Genome Res 2018 Dec 1. Epub 2018 Dec 1.

Coleoptera is the most diverse order among insects, and comparative molecular cytogenetic studies in this group are lacking. The species of Omophoita (Oedionychina) possess a karyotype of 2n = 22 = 10II+X+Y. They are interesting models for evolutionary cytogenetic studies due to giant sex chromosomes which are asynaptic during meiosis. Read More

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December 2018

Surgery for very large and giant intracranial aneurysms: Results and complications.

Neurol India 2018 Nov-Dec;66(6):1741-1757

Department of Neurosurgery, University of Washington, Seattle, Washington, USA.

Background: Results of and the complications encountered during surgery for very large and giant intracranial aneurysms are illustrated.

Objective: To analyze a consecutive series of patients with very large and giant aneurysms treated with microsurgery.

Methods: This retrospective study included seventy six very large and giant aneurysms which were managed by clipping and bypass technique. Read More

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December 2018

Microsurgery of giant intracranial aneurysms: Current status.

Neurol India 2018 Nov-Dec;66(6):1614-1616

Department of Neurosurgery and Gamma Knife Radiosurgery, P D Hinduja National Hospital and Medical Research Centre, Mumbai, Maharashtra, India.

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December 2018

Spontaneous migration of cellular aggregates from giant keratocytes to running spheroids.

Proc Natl Acad Sci U S A 2018 Nov 30. Epub 2018 Nov 30.

Laboratoire Physico Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168, 75005, Paris, France;

Despite extensive knowledge on the mechanisms that drive single-cell migration, those governing the migration of cell clusters, as occurring during embryonic development and cancer metastasis, remain poorly understood. Here, we investigate the collective migration of cell on adhesive gels with variable rigidity, using 3D cellular aggregates as a model system. After initial adhesion to the substrate, aggregates spread by expanding outward a cell monolayer, whose dynamics is optimal in a narrow range of rigidities. Read More

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November 2018
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High diversity and potential translocation of DNA viruses in ballast water.

Mar Pollut Bull 2018 Dec 27;137:449-455. Epub 2018 Oct 27.

South Sea Environment Research Department, Korea Institute of Ocean Science and Technology, Geoje 53201, Republic of Korea. Electronic address:

Ballast water is a common vector for the transport of invasive species to new marine and aquatic environments. We used a metagenomics approach to examine the composition and diversity of viral communities in ballast water from ships originating in Mexico, Saudi Arabia, New York, and Panama, and in water from the port of their destination in Busan, Korea. Myoviridae was the most abundant virus family in ballast water, followed Podoviridae and Siphoviridae. Read More

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December 2018

Nonoperative management of giant omphalocele leading to early fascial closure.

J Pediatr Surg 2018 Dec 2;53(12):2404-2408. Epub 2018 Sep 2.

Sunrise Children's Hospital, Las Vegas, NV.

Purpose: We describe our series of giant omphalocele patients treated with a serial taping method for gradual reduction of the abdominal contents and early fascial closure.

Methods: Between 2010 and 2017 we cared for ten newborns with giant omphaloceles. The average gestational age was 35. Read More

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December 2018
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[Giant gastric phytobezoar secondary to pyloric stenosis treated with Coca-Cola: A case report].

Semergen 2018 Nov 28. Epub 2018 Nov 28.

Servicio de Medicina Interna, Hospital Virgen de la Luz, Cuenca, España.

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November 2018

Histograms of Complete Blood Counts in Dogs: Maximizing Diagnostic Information.

Top Companion Anim Med 2018 Dec 3;33(4):141-146. Epub 2018 Jun 3.

Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Histograms, which are an integral part of the automated complete blood count, are now available through most of the automatic hematology analyzers used in veterinary clinical practice. Data concerning the size and number of blood cells are graphically presented in histograms, and their variations are also illustrated. Important information that is not apparent from numerical results are sometimes provided by histograms. Read More

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December 2018

Papillary pattern in clear cell renal cell carcinoma: Clinicopathologic, morphologic, immunohistochemical and molecular genetic analysis of 23 cases.

Ann Diagn Pathol 2018 Nov 22;38:80-86. Epub 2018 Nov 22.

Department of Pathology, Charles University, Faculty of Medicine in Plzeň, Pilsen, Czech Republic. Electronic address:

Clear cell renal cell carcinoma (ccRCC), the most common histologic subtype of RCCs, demonstrates a wide spectrum of morphologic features (i.e., low-grade spindle cell, syncytial giant cells, and mucin-producing cells). Read More

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November 2018

Is Heart Failure a High Tech Industrial Giant?

Authors:
Paul J Hauptman

J Card Fail 2018 Nov;24(11):721-722

University of Tennessee Graduate School of Medicine, Knoxville TN. Electronic address:

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November 2018

Golden Orbweavers Ignore Biological Rules: Phylogenomic and Comparative Analyses Unravel a Complex Evolution of Sexual Size Dimorphism.

Syst Biol 2018 Dec 4. Epub 2018 Dec 4.

Department of Entomology and Nematology, University of California Davis, 1 Shields Drive, Davis, CA, USA.

Instances of sexual size dimorphism (SSD) provide the context for rigorous tests of biological rules of size evolution, such as Cope's Rule (phyletic size increase), Rensch's Rule (allometric patterns of male and female size), as well as male and female body size optima. In certain spider groups, such as the golden orbweavers (Nephilidae), extreme female-biased SSD (eSSD, female:male body length ≥ 2) is the norm. Nephilid genera construct webs of exaggerated proportions, which can be aerial, arboricolous, or intermediate (hybrid). Read More

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December 2018

Survival predictors in biopsy-proven giant cell arteritis: a northern Italian population-based study.

Rheumatology (Oxford) 2018 Dec 4. Epub 2018 Dec 4.

Rheumatology Unit, Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia.

Objective: To evaluate the influence of disease-related findings and treatment outcomes on survival in a population-based cohort of Northern Italian patients with GCA.

Methods: A total of 281 patients with incident temporal artery biopsy (TAB)-proven GCA, diagnosed over a 26-year period (1986-2012) and living in the Reggio Emilia area, were retrospectively evaluated. We analysed clinical, imaging and laboratory findings at diagnosis, pathological patterns of TAB, CS treatment and therapeutic outcomes, and traditional cardiovascular risk factors as factors predictive of survival. Read More

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December 2018

LTD at mossy fiber synapses onto stratum lucidum interneurons requires TrkB and retrograde endocannabinoid signaling.

J Neurophysiol 2018 Dec 5. Epub 2018 Dec 5.

Dept. of Neurobiology, Duke University Medical Center, United States.

Hippocampal mossy fiber axons simultaneously activate CA3 pyramidal cells and stratum lucidum interneurons (SLIN), the latter providing feedforward inhibition to control CA3 pyramidal cell excitability. Filopodial extensions of giant boutons of mossy fibers provide excitatory synaptic input to the SLIN. These filopodia undergo extraordinary structural plasticity causally linked to executing memory tasks, leading us to seek the mechanisms by which activity regulates these synapses. Read More

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December 2018

ANO10 mutational screening in recessive ataxia: genetic findings and refinement of the clinical phenotype.

J Neurol 2018 Dec 4. Epub 2018 Dec 4.

Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, via Celoria 11, 20133, Milan, Italy.

Autosomal recessive cerebellar ataxia type 3 (ARCA3) is a rare inherited disorder caused by mutations in the ANO10 gene. The disease is characterized by slowly progressive spastic ataxia variably associated with motor neuron involvement, epilepsy, and cognitive decline. We performed mutational screening in 80 patients with sporadic or autosomal recessive adult-onset ataxia. Read More

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December 2018
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Is surgical parent artery occlusion effective for intracranial aneurysms measuring over 10 mm in size? Result from long-term follow-up of size changes and outcomes.

Acta Neurochir (Wien) 2018 Dec 4. Epub 2018 Dec 4.

Department of Neurosurgery, Showa University School of Medicine, 5-8 Hatanodai 1-chome, Shinagawa-ku, Tokyo, 142-8666, Japan.

Background: There have been no long-term follow-up reports pertaining to chronological size changes in large or giant unruptured intracranial aneurysms treated with surgical parent artery occlusion (PAO). The object of this study is to investigate the utility and safety of surgical PAO by conducting a long-term follow-up of chronological aneurysm size changes and outcomes.

Methods: A retrospective study of 21 unruptured intracranial aneurysms measuring over 10 mm (20 patients) treated with surgical PAO in the period 2012-2017 was conducted. Read More

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December 2018

Minimally invasive drainage of a giant ovarian mucinous cystadenoma associated with a mature cystic teratoma.

J Surg Case Rep 2018 Nov 30;2018(11):rjy322. Epub 2018 Nov 30.

Department of Surgery, Harvard Medical School, The Cambridge Hospital, Cambridge, MA, USA.

A 26-year-old, otherwise healthy female presented to the Emergency Room for the evaluation of abdominal pain. It was immediately apparent that she had a massively distended abdomen. History revealed progressive abdominal distension over several years. Read More

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November 2018

Giant Depolarizing Potentials Trigger Transient Changes in the Intracellular Cl Concentration in CA3 Pyramidal Neurons of the Immature Mouse Hippocampus.

Front Cell Neurosci 2018 20;12:420. Epub 2018 Nov 20.

Institute of Physiology, University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.

Giant depolarizing potentials (GDPs) represent a typical spontaneous activity pattern in the immature hippocampus. GDPs are mediated by GABAergic and glutamatergic synaptic inputs and their initiation requires an excitatory GABAergic action, which is typical for immature neurons due to their elevated intracellular Cl concentration ([Cl]). Because GABA receptors are ligand-gated Cl channels, activation of these receptors can potentially influence [Cl]. Read More

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November 2018

[Treatment of tuberculosis of lumbar spine in elderly patients with percataneous endoscopic focal cleaning and drainage combined with posterior internal fixation].

Zhongguo Gu Shang 2018 Nov;31(11):987-992

Department of Orthopaedics, Hangzhou Red Cross Hospital, Hangzhou, 310003, Zhejiang, China.

Objective: To explore the clinical effects and advantages of percataneous endoscopic focal cleaning and drainage combined with posterior internal fixation in the treatment of tuberculosis of lumbar spine in elderly.

Methods: The clinical data of 32 patients with tuberculosis of lumbar spine received percataneous endoscopic focal cleaning and drainage combined with posterior internal fixation from May 2013 to May 2016 were retrospectively analyzed. There were 13 males and 19 females, aged from 62 to 85 years old with an average of 75 years. Read More

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November 2018
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What Is the Giant Wall Gecko Having for Dinner? Conservation Genetics for Guiding Reserve Management in Cabo Verde.

Genes (Basel) 2018 Dec 3;9(12). Epub 2018 Dec 3.

CIBIO-InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Laboratório Associado da Universidade do Porto, Campus Agrário de Vairão, R. Padre Armando Quintas, 4485-661 Vairão, Portugal.

Knowledge on diet composition of a species is an important step to unveil its ecology and guide conservation actions. This is especially important for species that inhabit remote areas within biodiversity hotspots, with little information about their ecological roles. The emblematic giant wall gecko of Cabo Verde, is restricted to the uninhabited Branco and Raso islets, and presents two subspecies. Read More

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December 2018

The role of biologics in the treatment of giant cell arteritis.

Expert Opin Biol Ther 2018 Dec 4. Epub 2018 Dec 4.

d Rheumatology Division , Hospital de La Princesa, IIS-Princesa, Universidad Autónoma de Madrid (UAM) , Madrid , Spain .

Introduction: Giant cell arteritis is a vasculitis of large and middle-sized arteries that affects individuals older than 50 years. Although glucocorticoids remain the mainstay in the treatment of this vasculitis, other drugs are often required to achieve clinical remission and allow glucocorticoid discontinuation. Areas covered: The review summarizes the main biologic therapies used for the managements of GCA. Read More

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December 2018
2 Reads

Metamagnetism in Nanosheets of Co-MOF with T at 26 K and a Giant Hysteretic Effect at 5 K.

Inorg Chem 2018 Dec 4. Epub 2018 Dec 4.

Department of Chemistry , Indian Institute of Science Education and Research (IISER) , Dr. Homi Bhabha Road , Pune 411008 , India.

Herein, we have synthesized at room-temperature two-dimensional nanosheets of a MOF comprised of cobalt(II) ion with benzenedicarboxylic acid  ligand, which exhibited unusual magnetic properties. Direct-current magnetic susceptibility revealed an antiferromagnetic (AFM) transition at 26 K (Néel temperature,  T) followed by a canting of the spin moments along with the concomitant appearance of a sigmoidal-shaped magnetization versus field ( M- H) curve at 15 K. Such a canted AFM ordering led to nonzero remnant magnetization with a remarkably high coercive field of ∼10 kOe at 5 K. Read More

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December 2018
3 Reads

Atypical coronary artery aneurysms due to Kawasaki disease in Noonan syndrome with a novel PTPN11 mutation.

Cardiol Young 2018 Dec 4:1-3. Epub 2018 Dec 4.

3Department of Community Pediatrics,Perinatal and Maternal Medicine,Tokyo Medical and Dental University,Tokyo,Japan.

We report a 3-year-old boy with giant and atypical coronary artery aneurysms in the acute phase of Kawasaki disease, despite appropriate therapeutic intervention, in Noonan syndrome with a novel heterozygous PTPN11 mutation, c. 907 G>A (p.Asp303Asn). Read More

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December 2018
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MicroRNA from Small Oligunucletoides to Giant Players of Biological Processes and Diseases.

Authors:
Alberto Izzotti

Microrna 2019 ;8(1):2-3

Department of Health Sciences University of Genoa Genoa, Italy.

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January 2019

Data on the effect of a muscimol treatment in caspase activation in descending neurons of lampreys after a complete spinal cord injury.

Data Brief 2018 Dec 6;21:2037-2041. Epub 2018 Nov 6.

Department of Functional Biology, CIBUS, Faculty of Biology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.

In this article, caspase activation in identifiable reticulospinal neurons of lampreys was inhibited after a complete spinal cord injury using a specific agonist of the GABAA receptor (muscimol). The data presented in this article are quantifications of fluorescent labelling of identifiable descending neurons of larval lampreys after a complete spinal cord injury using fluorochrome-labelled inhibitors of caspases (FLICA) and the corresponding statistical analysis. A single dose of muscimol decreased the intensity of FLICA labelling in giant identifiable reticulospinal neurons following spinal cord injury in lampreys. Read More

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December 2018

Giant monostotic osteofibrous dysplasia of the ilium: A case report and review of literature.

World J Clin Cases 2018 Nov;6(14):830-835

Department of Orthopedics, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215002, Jiangsu Province, China.

Background: Osteofibrous dysplasia (OFD) is a developmental skeletal disorder, and cases with a giant affected area in the pelvis are rare.

Case Summary: In this case report, a 48-year-old man presented with a large tumor in the right iliac region that turned out to be OFD. The patient had rebound tenderness in his right hip. Read More

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November 2018

Cerebral Phosphorus Magnetic Resonance Spectroscopy in a Patient with Giant Cell Arteritis and Endovascular Therapy.

Case Rep Radiol 2018 28;2018:7806395. Epub 2018 Oct 28.

Department of Neuroradiology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.

With phosphorus magnetic resonance spectroscopy (31P MRS) energy metabolites can be visualised. In this case study, we report on a patient with stenosis and wall contrast enhancement in the left internal carotid and the right vertebral artery, due to giant cell arteritis. 31P MRS revealed a decreased inorganic phosphate-to-phosphocreatine ratio (Pi/PCr) in regions with a prolonged mean transit time (MTT). Read More

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October 2018

Giant tortoise genomes provide insights into longevity and age-related disease.

Nat Ecol Evol 2018 Dec 3. Epub 2018 Dec 3.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias, CIBERONC, Universidad de Oviedo, Oviedo, Spain.

Giant tortoises are among the longest-lived vertebrate animals and, as such, provide an excellent model to study traits like longevity and age-related diseases. However, genomic and molecular evolutionary information on giant tortoises is scarce. Here, we describe a global analysis of the genomes of Lonesome George-the iconic last member of Chelonoidis abingdonii-and the Aldabra giant tortoise (Aldabrachelys gigantea). Read More

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December 2018

Auditory perception exhibits sexual dimorphism and left telencephalic dominance in .

Biol Open 2018 Dec 3;7(12). Epub 2018 Dec 3.

Department of Herpetology, Chengdu Institute of Biology, Chinese Academy of Sciences, No.9 Section 4, Renmin South Road, Chengdu, Sichuan, People's Republic of China

Sex differences in both vocalization and auditory processing have been commonly found in vocal animals, although the underlying neural mechanisms associated with sexual dimorphism of auditory processing are not well understood. In this study we investigated whether auditory perception exhibits sexual dimorphism in To do this we measured event-related potentials (ERPs) evoked by white noise (WN) and conspecific calls in the telencephalon, diencephalon and mesencephalon respectively. Results showed that (1) the N1 amplitudes evoked in the right telencephalon and right diencephalon of males by WN are significantly different from those evoked in females; (2) in males the N1 amplitudes evoked by conspecific calls are significantly different from those evoked by WN; (3) in females the N1 amplitude for the left mesencephalon was significantly lower than for other brain areas, while the P2 and P3 amplitudes for the right mesencephalon were the smallest; in contrast these amplitudes for the left mesencephalon were the smallest in males. Read More

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December 2018

Pulmonary manifestations of large, medium, and variable vessel vasculitis.

Respir Med 2018 Dec 10;145:182-191. Epub 2018 Nov 10.

University of Texas Southwestern Medical Center, Department of Pulmonary and Critical Care Medicine, United States.

The hallmark of vasculitis is autoimmune inflammation of blood vessels and surrounding tissues, resulting in an array of constitutional symptoms and organ damage. The lung is commonly targeted in the more familiar ANCA-associated small vessel vasculitidies, but large and medium vessel vasculitides, including Takayasu arteritis, giant cell arteritis, polyarteritis nodosa, Behcet's disease, and necrotizing sarcoid granulomatosis, may also feature prominent pulmonary involvement. Pulmonary manifestations of these conditions include pulmonary arterial aneurysms, pulmonary hypertension, diffuse alveolar hemorrhage, pulmonary nodules, and parenchymal infiltrates. Read More

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December 2018

[A giant sacral chordoma resection and reconstruction with a gluteal perforator flap, a case report and literature review].

Ann Chir Plast Esthet 2018 Nov 30. Epub 2018 Nov 30.

Service de chirurgie orthopédique et traumatologie, chirurgie du rachis, hôpital Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France.

Background: Sacral chordomas are rare primary bone tumors and represent more than half of all primary malignant sacral tumors. Surgical resection is the only treatment with close to 50% of remission at 10 years, with or without radiotherapy. This tissue removal can be very extensive and morbid, particularly for evolved tumors. Read More

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November 2018