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Biomed Mater 2022 Jun 24;17(4). Epub 2022 Jun 24.

Department of Orthopedics and Rehabilitation, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou 313000, People's Republic of China.

Titanium dioxide (TiO), as one of the titanium (Ti)-based implants, holds a promise for a variety of anti-bacterial application in medical research. In the current study, a functional molybdenum disulfide (MoS)/polydopamine (PDA)-LL-37 coating on titanium dioxide (TiO) implant was prepared. Anodic oxidation and hydrothermal treatment was given to prepare TiOnanotubes-MoS/PDA-LL-37 (T-M/P-L). Read More

Can Geriatr J 2022 Jun 1;25(2):202-211. Epub 2022 Jun 1.

Canadian Frailty Network, Kingston, ON.

The Canadian population is aging. With aging, biological and social changes occur increasing the risk of developing chronic conditions and functional loss leading to frailty. Older adults living with frailty are more vulnerable to minor stressors, take longer to recover from illness, and have difficulty participating in daily activities. Read More

HPA Resour 2018 Aug;18(3):5-16

Physical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado, Aurora, CO.

There is growing recognition that acute hospitalization contributes to marked functional decline in older adult populations. Nearly 20% of all hospitalized older adults in the United States are discharged to skilled nursing facilities (SNFs) to address these functional deficits. However, current approaches to care in SNFs may not adequately restore function, which may contribute to low community discharge rates and high hospital readmission rates. Read More

Medicina (Kaunas) 2022 Jun 15;58(6). Epub 2022 Jun 15.

Klinik für Orthopädie, Unfallchirurgie und Sporttraumatologie, Marienhaus Klinikum Hetzelstift, 67434 Neustadt an der Weinstraße, Germany.

: The number of geriatric patients presenting with fragility fractures of the pelvis is increasing due to ageing Western societies. There are nonoperative and several operative treatment approaches. Many of which cause prolonged hospitalisation, so patients become bedridden and lose mobility and independence. Read More

Healthcare (Basel) 2022 Jun 20;10(6). Epub 2022 Jun 20.

Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino-shi 583-8555, Japan.

Empowerment scales for inpatients have been developed worldwide, but their validity and reliability have not been adequately tested and applied to the health promotion and care among older adults during hospitalization. In this study, the Patient Empowerment Scale developed by Faulkner was translated into Japanese, and Japanese patients were surveyed to test its clinical applicability. To test its applicability, 151 patients in rehabilitation wards were surveyed in four municipalities. Read More

Healthcare (Basel) 2022 May 31;10(6). Epub 2022 May 31.

Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

Assessing multiple domains of health in older adults requires multidimensional and large datasets. Consensus on definitions, measurement protocols and outcome measures is a prerequisite. The Physical Activity and Nutritional INfluences In Ageing (PANINI) Toolkit aims to provide a standardized toolkit of best-practice measures for assessing health domains of older adults with an emphasis on nutrition and physical activity. Read More

JMIR Mhealth Uhealth 2022 Jun 23;10(6):e32910. Epub 2022 Jun 23.

Institute of the History, Philosophy and Ethics of Medicine, Ulm University, Ulm, Germany.

Background: Smart sensors have been developed as diagnostic tools for rehabilitation to cover an increasing number of geriatric patients. They promise to enable an objective assessment of complex movement patterns.

Objective: This research aimed to identify and analyze the conflicting ethical values associated with smart sensors in geriatric rehabilitation and provide ethical guidance on the best use of smart sensors to all stakeholders, including technology developers, health professionals, patients, and health authorities. Read More

Front Psychiatry 2022 6;13:910814. Epub 2022 Jun 6.

Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Aims: The purpose of this study was to investigate the prevalence, influencing factors, and clinical characteristics of cognitive impairment in elderly patients with chronic schizophrenia.

Materials And Methods: A total of 264 elderly patients with chronic schizophrenia and 156 normal controls were enrolled in the current study. The Mini-mental State Examination (MMSE) was used to assess their overall cognitive function, the Positive And Negative Syndrome Scale (PANSS) was used to assess their psychotic symptoms, the Geriatric Depression Scale (GDS) was used to assess their depressive symptoms, while Activity of Daily Living Scale (ADL) was used to assess their daily living ability. Read More

Adv Gerontol 2022 ;35(2):191-205

I.I.Mechnikov North-Western State Medical University, 41 Kirochnaya str., St. Petersburg 193015, Russian Federation, e-mail:

In addition to the rapid and rippling spread of the pandemic across the globe today, there is a growing problem called «long-COVID-19», a term that describes the long-term effects of a new coronavirus infection COVID-19. How the disease proceeds after «recovery», including the long-term physical and psychological health consequences, the future of COVID-19 survivors remains largely unclear. This is especially true for the contingent older age groups. Read More

Am J Occup Ther 2022 Jul;76(4)

Min-Yuan Yu, BS, is Occupational Therapist, Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan;

Importance: Psychometric examinations for patients with stroke remain insufficient. The Center for Epidemiologic Studies Depression Scale (CES-D), Beck Depression Inventory-II (BDI-II), and Geriatric Depression Scale (GDS) are promising outcome measures.

Objective: To examine and compare the reliability and validity of three depression measures in a sample of patients with stroke. Read More

Aging Clin Exp Res 2022 Jun 21. Epub 2022 Jun 21.

Department of Geriatric Medicine, Hospital District of Southern Ostrobothnia, Hanneksenrinne 7, 60220, Seinäjoki, Finland.

Background: Hip fracture causes not only physical injury but also psychological trauma. Fear of falling (FoF) is related to poor recovery, loss of mobility and mortality. There is limited data on the clinical factors affecting post-hip fracture FoF and its consequences. Read More

Front Psychol 2022 3;13:869573. Epub 2022 Jun 3.

Department of Public Health and Clinical Medicine, Section of Sustainable Health, Umeå University, Umeå, Sweden.

Background: Physical inactivity and low muscle mass are risk factors for falls, fractures and overall poor health. However, physical activity is reduced with increased age and only a fraction of older adults engages in resistance training (RT). Thus, strategies that facilitate RT among older adults are needed. Read More

BMJ Open 2022 Jun 20;12(6):e059388. Epub 2022 Jun 20.

Western Australian Centre for Health and Ageing, Medical School, The University of Western Australia, Perth, Western Australia, Australia.

Introduction: Hospitalised older adults are prone to functional deterioration, which is more evident in frail older patients and can be further exacerbated by pain. Two interventions that have the potential to prevent progression of frailty and improve patient outcomes in hospitalised older adults but have yet to be subject to clinical trials are nurse-led volunteer support and technology-driven assessment of pain.

Methods And Analysis: This single-centre, prospective, non-blinded, cluster randomised controlled trial will compare the efficacy of nurse-led volunteer support, technology-driven pain assessment and the combination of the two interventions to usual care for hospitalised older adults. Read More

Arch Gerontol Geriatr 2022 Jun 9;102:104749. Epub 2022 Jun 9.

Department of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, 1-1, Yazakokarimata, Nagakute, Aichi 480-1195, Japan; Department of Geriatric Medicine, Hospital, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi 474-8511, Japan. Electronic address:

Objectives: Whether decreased tongue strength is associated with poor clinical outcomes is unclear. This systematic review investigated the effect of decreased tongue strength on the clinical outcomes of adults requiring medical treatment.

Design: Systematic review. Read More

JMIR Form Res 2022 Jun 20;6(6):e35365. Epub 2022 Jun 20.

Department of Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark.

Background: Aortic valve stenosis affects approximately half of people aged ≥85 years, and the recommended surgical treatment for older patients is transcatheter aortic valve implantation (TAVI). Despite strong evidence for its advantages, low attendance rate in cardiac rehabilitation is observed among patients after TAVI. Cardiac telerehabilitation (CTR) has proven comparable with center-based rehabilitation; however, no study has investigated CTR targeting patients after TAVI. Read More

J Geriatr Cardiol 2022 May;19(5):377-392

Servicio de Cardiología, Hospital Bellvitge de Barcelona, Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.

In recent decades, life expectancy has been increasing significantly. In this scenario, health interventions are necessary to improve prognosis and quality of life of elderly with cardiovascular risk factors and cardiovascular disease. However, the number of elderly patients included in clinical trials is low, thus current clinical practice guidelines do not include specific recommendations. Read More

Front Bioeng Biotechnol 2022 2;10:868928. Epub 2022 Jun 2.

Department of Mechanical Engineering, Insigno Institute for In Silico Medicine, The University of Sheffield, Sheffield, United Kingdom.

There is growing interest in the quantification of gait as part of complex motor tasks. This requires gait events (GEs) to be detected under conditions different from straight walking. This study aimed to propose and validate a new marker-based GE detection method, which is also suitable for curvilinear walking and step negotiation. Read More

Hypertens Res 2022 Jun 20. Epub 2022 Jun 20.

Division of Public Health, Hygiene and Epidemiology, Tohoku Medical and Pharmaceutical University, Sendai, Japan.

We assessed blood pressure (BP) changes during fiscal years (April to March of the following year) 2015-2020 to clarify the effect of the state of emergency due to the coronavirus disease 2019 (COVID-19) pandemic in 2020. We then considered BP in 2019 separately, as the Japanese hypertension guidelines were updated in 2019. The present retrospective cohort study extracted data from 157,510 Japanese individuals aged <75 years (mean age: 50. Read More

J Cachexia Sarcopenia Muscle 2022 Jun 19. Epub 2022 Jun 19.

School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.

Background: Despite recent advances in understanding the pathophysiology of cancer cachexia, prevention/treatment of this debilitating disease remains an unmet medical need.

Methods: We developed an integrated, multi-tiered strategy involving both in vitro and in vivo muscle atrophy platforms to identify traditional Chinese medicine (TCM)-based anti-cachectic agents. In the initial screening, we used inflammatory cytokine-induced atrophy of C2C12 myotubes as a phenotypic screening platform to assess the protective effects of TCMs. Read More

Neuroimage Clin 2022 Jun 14;35:103083. Epub 2022 Jun 14.

Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, China; School of Psychology, Center for Studies of Psychological Application, and Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, 510631 Guangzhou, China. Electronic address:

Background: Compulsive behaviors in obsessive-compulsive disorder (OCD) have been suggested to result from an imbalance in cortico-striatal connectivity. However, the nature of this impairment, the relative involvement of different striatal areas, their imbalance in genetically related but unimpaired individuals, and their relationship with cognitive dysfunction in OCD patients, remain unknown.

Methods: In the current study, striatal (i. Read More

Int J Cardiol 2022 Jun 15. Epub 2022 Jun 15.

Department of Medical Consultation Center, Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address:

Background: The influencing factors of kinesiophobia (fear of movement) in patients with atrial fibrillation(AF)during the post-operative "Blanking Period" are not known. The aims were to investigate the status of kinesiophobia in patients with AF during the post-operative "Blanking Period", then further describe the occurrence and analyze the influencing factors of patients' kinesiophobia by the Fear-Avoidance Model.

Materials And Methods: In total,400 patients diagnosed with atrial fibrillation, during the post-operative "Blanking Period" from the selected hospital were included in this study. Read More

Geriatr Gerontol Int 2022 Jun 18. Epub 2022 Jun 18.

Medicine Academic Programme, Duke-NUS Graduate Medical School, Singapore, Singapore.

Aim: In order to account for the variability in gait speed due to demographic factors, an observed gait speed value can be compared with its predicted value based on age, sex, and body height (observed gait speed divided by predicted gait speed, termed "GS%predicted" henceforth). This study aimed to examine the screening accuracy of an optimal GS%predicted threshold for prefrailty/frailty.

Methods: This cross-sectional study included 998 community-dwelling ambulant participants aged >50 years (mean age = 68 years). Read More

Nutr Clin Pract 2022 Jun 16. Epub 2022 Jun 16.

Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Background: Several studies reported that impaired nutrition is associated with reduced muscle mass, muscle strength, and physical performance. Chewing ability is essential to maintain balanced oral nutrient intake. The study was designed to define the possible relationship between chewing ability and nutrition-related problems (malnutrition, sarcopenia, and frailty) in a holistic perspective. Read More

Ir J Med Sci 2022 Jun 16. Epub 2022 Jun 16.

Department of Obstetrics and Gynecology, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey.

Background: Our study aims to determine whether different self-efficacy (SE) levels affect urinary incontinence symptoms, falls, quality of life, sleep, and physical activity in elderly individuals with incontinence. Our secondary aim is to examine the relationship between SE levels and urinary incontinence severity, quality of life, sleep status, fear of falling, and physical activity level.

Methods: One hundred twenty elderly individuals (median age: 71 years) with urinary incontinence participated in the cross-sectional study. Read More

BMC Infect Dis 2022 Jun 15;22(1):547. Epub 2022 Jun 15.

Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, Umeå, Sweden.

Background: Our aim was to describe the annual prevalence of herpes simplex virus (HSV) reactivation in relation to solar ultraviolet (UV) radiation and antiviral drug use in the Swedish adult population.

Methods: The study comprised 2879 anti-HSV-1 immunoglobulin (Ig) G positive subjects from five different cohorts who had donated serum from 1988 to 2010. The sera were analyzed for anti-HSV IgM using enzyme-linked immunosorbent assay. Read More

Clin Med (Lond) 2022 Jun 15. Epub 2022 Jun 15.

University Hospital Llandough, Llandough, UK.

A recent article identified weaknesses in the management of patients with traumatic brain injury (TBI). The authors suggested some reasons but overlooked two of the reasons for the low quality of services: a lack of resources and a systemic failure to organise rehabilitation services. They suggested early involvement of a condition-specific service with a new 'neuroscience clinician' and additional neuro-navigators, but the evidence shows this approach does not work. Read More

BMJ Open 2022 Jun 15;12(6):e060373. Epub 2022 Jun 15.

Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand

Introduction: Neck pain (NP) is a common musculoskeletal complaint and is increasing in prevalence. Current clinical practice guidelines and systematic reviews recommended conservative, pharmacological and invasive interventions for individuals with NP. However, optimal management specifically for those who are middle-aged or older adults (≥45 years) is not available; and important considering our ageing population. Read More

PLoS One 2022 16;17(6):e0269961. Epub 2022 Jun 16.

School of Allied Health, Ageing Research Centre, Faculty of Education and Health Sciences, Health Research Institute, University of Limerick, Limerick, Ireland.

Purpose: Stroke is a leading cause of death and disability worldwide. Despite the prevalence and associated burden of post-stroke cognitive impairment, there is uncertainty regarding optimum interventions to improve cognitive function in people post-stroke. The aim of this study is to explore the perspectives of key stakeholders on the design and development of a multidisciplinary intervention to rehabilitate cognitive deficits in people post-stroke. Read More

IEEE Trans Neural Syst Rehabil Eng 2022 Jun 16;PP. Epub 2022 Jun 16.

Ageing populations are becoming a global issue. Against this background, the assessment and treatment of geriatric conditions have become increasingly important. This study draws on the multisensory integration of virtual reality (VR) devices in the field of rehabilitation to assess brain function in young and old people. Read More

Aging Clin Exp Res 2022 Jun 16. Epub 2022 Jun 16.

Department of Geriatric Medicine, University of Auckland, Auckland, New Zealand.