565 results match your criteria Geographic Tongue


Association of geographic tongue and fissured tongue with ABO blood group among adult psoriasis patients: a novel study from a tertiary care hospital in Saudi Arabia.

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Feb 7. Epub 2019 Feb 7.

Assistant Professor, Department of Periodontics and Community Sciences, College of Dentistry, King Khalid University, Abha, Kingdom of Saudi Arabia.

Objective: We aimed to determine if there was any association between geographic tongue (GT) and fissured tongue with ABO blood group among adult psoriasis patients in Saudi Arabia.

Study Design: This hospital-based cross-sectional study included 100 consecutive new adult patients diagnosed with psoriasis and 100 case-matched participants in the control group (nonpsoriatic). Sociodemographic and dermatologic parameters, intraoral lesions (GT and fissured tongue), and ABO blood grouping and immunoglobulins were recorded and evaluated using χ or Fisher's exact test. Read More

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http://dx.doi.org/10.1016/j.oooo.2019.01.080DOI Listing
February 2019

First case of Roma ethnic origin with Andermann syndrome: A novel frameshift mutation in exon 20 of SLC12A6 gene.

Am J Med Genet A 2019 Mar 13. Epub 2019 Mar 13.

Department of Pediatrics and Medical Genetics, Medical University, Plovdiv, Bulgaria.

Andermann syndrome (AS) is caused by mutation of SLC12A6 gene. It comprises severe progressive sensory and motor neuropathy with early onset, varying degree of agenesis of corpus callosum (ACC) and mental retardation. AS occurs occasionally among population outside the northeastern Quebec-Saguenay-Lac- St-Jean and Charlevoix regions, inhabited by French Canadians. Read More

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http://dx.doi.org/10.1002/ajmg.a.61110DOI Listing

Association between geographic tongue and psoriasis: A systematic review and meta-analyses.

J Oral Pathol Med 2019 Feb 9. Epub 2019 Feb 9.

Oral Medicine Unit, Faculty of Medicine and Sciences of the Health, University of Oviedo, Oviedo, Spain.

Geographic tongue (GT) has been described as a predictor of psoriasis. The objective of this study was to analyse the prevalence of GT in psoriatic and non-psoriatic patients. For this purpose, we conducted a systematic review and meta-analysis. Read More

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http://dx.doi.org/10.1111/jop.12840DOI Listing
February 2019
1 Read

Erythematous and Vascular Oral Mucosal Lesions: A Clinicopathologic Review of Red Entities.

Head Neck Pathol 2019 Mar 29;13(1):4-15. Epub 2019 Jan 29.

The Ohio State University, 305 W. 12 Ave, Columbus, OH, 43210, USA.

Erythematous lesions of the oral mucosa are common and can reflect a variety of conditions, ranging from benign reactive or immunologically-mediated disorders to malignant disease. Together with vascular abnormalities, which can vary from reddish to bluish-purple in color, the differential diagnosis for erythematous oral mucosal change is quite diverse. This review focuses on salient clinical features and histopathologic findings of selected conditions which clinically present as red or vascular-like oral mucosal alterations, including oral vascular malformations and neoplasms, pyogenic granuloma, localized juvenile spongiotic gingival hyperplasia, denture stomatitis, benign migratory glossitis (geographic tongue), orofacial granulomatosis, granulomatosis with polyangiitis (Wegener granulomatosis), megaloblastic anemia, and erythroplakia. Read More

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http://dx.doi.org/10.1007/s12105-019-01002-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405795PMC
March 2019
3 Reads

Prevalence of oral mucosal disorders during pregnancy: A systematic review and meta-analysis.

J Oral Pathol Med 2019 Jan 23. Epub 2019 Jan 23.

Brazilian Centre for Evidence-Based Research, Federal University of Santa Catarina (UFSC), Florianópolis, Santa Catarina, Brazil.

Objective: To assess the prevalence of oral mucosal disorders during pregnancy.

Methods: Observational studies were selected by two reviewers in a two-phase process. Search strategies were applied at CINAHL, LILACS, LIVIVO, PubMed, Scopus, Web of Science, Google Scholar, OpenGrey, and ProQuest. Read More

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http://dx.doi.org/10.1111/jop.12831DOI Listing
January 2019
5 Reads

Anxiety and genetic polymorphisms in catechol-O-methyltransferase (COMT) and serotonin transportation gene (5HTT) are associated with benign migratory glossitis.

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Mar 10;127(3):218-224. Epub 2018 Nov 10.

Professor at School of Life Sciences, Pontifical Catholic University of Paraná, Curitiba, Brazil.

Objective: The aim of this case-control study was to investigate whether benign migratory glossitis (BMG) is associated with catechol-O-methyltransferase (COMT) and serotonin transportation gene (5HTT) polymorphisms and anxiety.

Study Design: The study comprised 43 patients with BMG and 114 patients without a history of BMG. We used the Hamilton Anxiety (HAM-A) rating scale to assess each individual's anxiety. Read More

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http://dx.doi.org/10.1016/j.oooo.2018.10.011DOI Listing

Prevalence of oral squamous cell carcinoma in Bareilly Region: A seven year institutional study.

J Exp Ther Oncol 2018 Nov;12(4):323-330

Department of Oral and Maxillofacial Pathology, Bareilly International University, Institute of Dental Sciences, Bareilly, (UP), India.

Background: Oral squamous cell carcinoma is a major contributor to disability and death caused by malignant tumors. Variations in social, cultural, and geographic factors affect the tumor behavior and response to treatment. In this study, we undertake a seven years institutional review and analysis of Oral squamous cell carcinoma cases in Bareilly. Read More

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November 2018
4 Reads

Effectiveness of the Tacrolimus Swish-and-Spit Treatment Regimen in Patients With Geographic Tongue.

JAMA Dermatol 2018 Dec;154(12):1481-1482

Department of Dermatology, Center for Research, Wake Forest School of Medicine, Winston-Salem, North Carolina.

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http://dx.doi.org/10.1001/jamadermatol.2018.3806DOI Listing
December 2018

Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.

Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39

Institut Universitaire du Cancer Toulouse - Oncopole, 1 avenue Irène Joliot-Curie, 31059, TOULOUSE Cedex 9, France.

Targeted therapies and immunotherapies are associated with a wide range of dermatologic adverse events (dAEs) resulting from common signaling pathways involved in malignant behavior and normal homeostatic functions of the epidermis and dermis. Dermatologic toxicities include damage to the skin, oral mucosa, hair, and nails. Acneiform rash is the most common dAE, observed in 25-85% of patients treated by epidermal growth factor receptor and mitogen-activated protein kinase kinase inhibitors. Read More

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http://link.springer.com/10.1007/s40257-018-0384-3
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http://dx.doi.org/10.1007/s40257-018-0384-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244569PMC
November 2018
16 Reads

Geographic tongue that responds to the treatment of pregabalin: Can it be a new treatment choice?

Dermatol Ther 2019 01 18;32(1):e12776. Epub 2018 Nov 18.

Department of Dermatology, Selcuk University Medicine Faculty, Konya, Turkey.

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http://doi.wiley.com/10.1111/dth.12776
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http://dx.doi.org/10.1111/dth.12776DOI Listing
January 2019
12 Reads

Geographic tongue induced by angiogenesis inhibitors.

Rev Clin Esp 2018 Dec 15;218(9):501-502. Epub 2018 Oct 15.

Departamento de Farmacia, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, España.

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https://linkinghub.elsevier.com/retrieve/pii/S00142565183024
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http://dx.doi.org/10.1016/j.rce.2018.07.008DOI Listing
December 2018
9 Reads

[Oral allergies].

Authors:
L Evrard

Rev Med Brux 2018;39(4):317-321

Service de Dentisterie - Chirurgie orale et maxillo-faciale - Orthodontie - Stomatologie, Hôpital Erasme, ULB.

Oral allergies to dental materials are a growing problem and remain poorly diagnosed by health professionals. The complaints of patients with oral allergy are various and include sensations of burning or stinging of the oral mucosa, sensations of dryness of the oral cavity, or general symptoms such as headache, dyspepsia, asthenia, arthralgia, and myalgia. Signs suggestive of oral allergy include erythema, edema, purpuric patches on the palate, ulcerations of the oral mucosa (canker sore), gingivitis, glossitis mimicking geographic tongue, angular cheilitis, peri-oral eczema or the presence of lichenoid reactions of the oral mucosa. Read More

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December 2018
1 Read

Epidemiology of oral mucosal lesions in Slovenia.

Radiol Oncol 2018 Sep 11;52(3):263-266. Epub 2018 Sep 11.

Private Dental Practice, Ljubljana, Slovenia.

Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not the most common lesions that might appear in the oral cavity. Since most of the studies are focused on the detection of cancer in the oral cavity, we were interested in detecting the frequency of benign changes of the oral mucosa in Slovene population. Oral mucosal lesions are important pointer of oral health and quality of life, especially in elderly. Read More

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http://dx.doi.org/10.2478/raon-2018-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137360PMC
September 2018
2 Reads

Frequency of Pathologic Changes in the Oral Cavity in Patients Subjected to Long-term Pharmacologic Immunosuppressive Therapy After Kidney, Liver, and Hematopoietic Cell Transplantation.

Transplant Proc 2018 Sep 11;50(7):2176-2178. Epub 2018 Apr 11.

Department of General and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland.

Introduction: Patients subjected to long-term immunosuppressive therapy after organ and cells transplantation are more susceptible than healthy people to the development of the pathologic changes in the oral cavity, including precancerous lesions, oral cancers, lesions following viral infections (herpes simplex virus, Epstein-Barr virus, and cytomegalovirus), fungal infections mainly caused by Candida albicans, drug-induced gingival overgrowth, stomatitis, and tongue disorders.

Material And Methods: Clinical case material included 38 patients after kidney, liver, or blood-forming cells transplantation subjected to various immunosuppressive therapy schemes. The study comprised standard case taking and physical examination of the patient, including detailed intraoral and extraoral stomatological examinations. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.04.003DOI Listing
September 2018
16 Reads

Particular shape of the tongue and benign migratory glossitis.

Pan Afr Med J 2018;30:11. Epub 2018 May 7.

University of Milan, Department of Radiology, Milano, Italy.

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http://dx.doi.org/10.11604/pamj.2018.30.11.15490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110545PMC
October 2018
3 Reads

The burden of Diabetes, Its Oral Complications and Their Prevention and Management.

Open Access Maced J Med Sci 2018 Aug 15;6(8):1545-1553. Epub 2018 Aug 15.

College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Background: Diabetes mellitus (DM), chronic disease, is a public health problem that affects 8.5% adult population worldwide. The number of adults with DM has risen sharply from 108 million in 1980 to 422 million in 2014. Read More

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http://dx.doi.org/10.3889/oamjms.2018.294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108795PMC
August 2018
16 Reads

[Deaths due to oral cancer in Chile in the period 2002-2012].

Rev Med Chil 2018 Apr;146(4):487-493

Escuela de Salud Pública, Universidad de Chile, Santiago, Chile.

Background: Oral cancer is the 15th most common cause of cancer death in the world. In Chile, 1% of all cancer deaths are related to oral and pharyngeal cancer.

Aim: To determine mortality rates for oral cancer in Chile and its regions between 2002-2012. Read More

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http://dx.doi.org/10.4067/s0034-98872018000400487DOI Listing
April 2018
7 Reads

Treatment of symptomatic benign migratory glossitis: a systematic review.

Clin Oral Investig 2018 Sep 7;22(7):2487-2493. Epub 2018 Jul 7.

Department of Stomatology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes 2227 (Butantã), São Paulo, Brazil.

Objective: The aim of this systematic review is to summarize the results of all published studies on symptomatic benign migratory glossitis and evaluate the best available treatment.

Methods: We searched the Cochrane Library, EMBASE, LILACS, PubMed, Scopus, and Web of Science for articles published up to September 2017, with no time restriction. We considered only articles published in English that evaluated the treatment of symptomatic benign migratory glossitis in children and adults. Read More

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http://dx.doi.org/10.1007/s00784-018-2553-4DOI Listing
September 2018
10 Reads

Unusual tongue. Painful tongue.

Authors:
Tanya M Gibson

Gen Dent 2018 Jul-Aug;66(4):76-78

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January 2019
1 Read

Geographic tongue: Predisposing factors, diagnosis and treatment. A systematic review.

Rev Clin Esp 2018 Dec 11;218(9):481-488. Epub 2018 Jun 11.

Departamento de Cirugía y Especialidades Médico-Quirúrgicas, Facultad de Medicina, Universidad de Oviedo, Oviedo, España.

Introduction: Geographic tongue (GT) is a lesion of unknown origin associated with systemic diseases and therefore involves multidisciplinary care.

Methods: We performed a literature search of the PubMed, EMBASE, Web of Science and Cochrane databases. The selection criteria were consistent with the Preferred Reporting Items for Systematic Reviews protocol. Read More

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http://dx.doi.org/10.1016/j.rce.2018.05.006DOI Listing
December 2018
1 Read

Transverse venous sinus stenting for idiopathic intracranial hypertension: Safety and feasibility.

Neuroradiol J 2018 Oct 8;31(5):513-517. Epub 2018 Jun 8.

Indiana University Department of Radiology and Imaging Sciences, Indianapolis, USA.

Purpose Transverse sinus stenosis is commonly seen in patients with idiopathic intracranial hypertension. It is not clear whether it is the cause or the result of idiopathic intracranial hypertension. Stenting for idiopathic intracranial hypertension has been carried out in several prior series. Read More

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http://dx.doi.org/10.1177/1971400918782320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136131PMC
October 2018
20 Reads

Tongue psoriasis: Clinical aspects and analysis of epidemiological associations in 313 children, with a systematic literature review.

Ann Dermatol Venereol 2018 Oct;145(10):578-586

Dermatology department, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil, France. Electronic address:

Background: Little information is available on the prevalence and clinical aspects of tongue involvement in children with psoriasis. The aim was to evaluate the prevalence, clinical aspects and risk factors concerning tongue involvement in children with psoriasis.

Patients And Methods: This study was carried out in two stages. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01519638183038
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http://dx.doi.org/10.1016/j.annder.2018.04.003DOI Listing
October 2018
6 Reads

A pragmatic evidence-based clinical management algorithm for burning mouth syndrome.

J Clin Exp Dent 2018 Apr 1;10(4):e321-e326. Epub 2018 Apr 1.

MD, Department of Otolaryngology - Head and Neck Surgery, Loma Linda University Medical Center, Loma Linda, CA, USA.

Background: Burning mouth syndrome is a poorly understood disease process with no current standard of treatment. The goal of this article is to provide an evidence-based, practical, clinical algorithm as a guideline for the treatment of burning mouth syndrome.

Material And Methods: Using available evidence and clinical experience, a multi-step management algorithm was developed. Read More

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http://dx.doi.org/10.4317/jced.54247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937967PMC
April 2018
3 Reads

Acrodermatitis continua of Hallopeau and geographic tongue are variants of pustular psoriasis.

Authors:
Muriel Sadlier

JAAD Case Rep 2018 Apr 7;4(3):277. Epub 2018 Mar 7.

Department of Dermatology, St James's Hospital Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jdcr.2017.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909475PMC
April 2018
3 Reads

An infant with generalized pustular psoriasis and geographic tongue had a heterozygous IL36RN mutation and IgG2 deficiency.

J Dermatol Sci 2018 May 6;90(2):216-218. Epub 2018 Feb 6.

Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2018.01.017DOI Listing
May 2018
9 Reads

Geographic tonguelike presentation in a child with pityriasis rosea: Case report and review of oral manifestations of pityriasis rosea.

Pediatr Dermatol 2018 Mar 13;35(2):e124-e127. Epub 2018 Feb 13.

Division of Dermatology, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Oral lesions are rarely reported in patients with pityriasis rosea. We report a case of a 3-year-old boy with clinical evidence of generalized pityriasis rosea who developed asymptomatic oral lesions similar in appearance to geographic tongue. The generalized eruption and tongue lesions resolved simultaneously within 4 weeks. Read More

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http://dx.doi.org/10.1111/pde.13417DOI Listing
March 2018
3 Reads

Benign Migratory Glossitis.

J Coll Physicians Surg Pak 2018 Feb;28(2):175-176

Department of Psychiatry, Pak Field Hospital Darfur, Sudan.

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http://dx.doi.org/10.29271/jcpsp.2018.02.175DOI Listing
February 2018
3 Reads

Prevalence and heritability of psoriasis and benign migratory glossitis in one Brazilian population.

An Bras Dermatol 2017 Nov-Dec;92(6):816-819

Department of Genetics and Evolution, Faculty of Health Sciences, Universidade Federal de São Carlos (UFSCar) - São Carlos (SP), Brazil.

Background: An oral condition associated to psoriasis is benign migratory glossitis. The review of the literature does not show any publication about heritability in both soriasis and benign migratory glossitis and prevalence of psoriasis in the Brazilian population.

Objective: This research was carried out in order to determine the prevalence of psoriasis and benign migratory glossitis in the Brazilian population from a Brazilian sample, as well as the heritability in these conditions. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20176389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786396PMC
April 2018
4 Reads

Prevalence of Oral Mucosal Lesions and Their Association with Severity of Psoriasis among Psoriatic Patients Referred To Dermatology Clinic: A Cross-Sectional Study in Kashan/Iran.

Open Access Maced J Med Sci 2017 Dec 24;5(7):978-982. Epub 2017 Oct 24.

Kashan University of Medical Sciences, Kashan, Iran.

Background: Psoriasis is a common inflammatory papulosquamous disease of the skin with unknown aetiology that may be associated with the abnormal T-cell function.

Aim: This study was aimed to determine the prevalence of oral mucosal lesions and their associations with severity of psoriasis in psoriatic patients attending the dermatologic clinic of Shahid Beheshti Teaching Hospital at Kashan, Iran.

Methods: In this cross-sectional descriptive analytic study, all consecutive patients with psoriasis who referred to the dermatologic clinic at the Shahid Beheshti Hospital of Kashan University of Medical Sciences in Kashan City/ Iran were enrolled. Read More

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http://dx.doi.org/10.3889/oamjms.2017.189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771307PMC
December 2017
7 Reads

Oral features in patients with psoriasis: an observational study.

Minerva Stomatol 2018 02;67(1):12-19

Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.

Background: The aim of this study was to investigate and compare the prevalence of oral mucosal lesions in a group of psoriatic patients and healthy subjects.

Methods: 120 psoriatic patients were enrolled in this observational study. Clinical examination, panoramic X-ray, magnetic nuclear resonance of temporo-mandibular joint, parodontal evaluation, oropharyngeal buffer and incisional biopsies by scalpel, as applicable, were done in order to value the patients. Read More

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http://dx.doi.org/10.23736/S0026-4970.17.04066-3DOI Listing
February 2018
5 Reads

Tooth Wear Is Frequent in Adult Patients with Celiac Disease.

Nutrients 2017 Dec 4;9(12). Epub 2017 Dec 4.

Department of Medicine, Surgery and Dentistry, Medical School of Salerno, 84131 Salerno, Italy.

(1) Background: Celiac disease (CD) patients can be affected by mouth and tooth disorders, which are influenced by their gluten-free diet. The aim of our research was to evaluate the pathological conditions of the stomatognathic system observed in celiac patients on a gluten-free diet. (2) Methods: we consecutively recruited celiac patients on a gluten-free diet at our celiac center, as well as healthy volunteers. Read More

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http://dx.doi.org/10.3390/nu9121321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748771PMC
December 2017
7 Reads

Benign Migratory Glossitis.

J Emerg Med 2018 Jan 27;54(1):e9-e10. Epub 2017 Oct 27.

Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.jemermed.2017.09.035DOI Listing
January 2018
4 Reads

[GLOBAL INCIDENCE AND RISK FACTORS OF ORAL CANCER].

Harefuah 2017 Oct;156(10):645-649

The Padeh Baruch Medical Center, Poriya.

Introduction: Cancer of the oral cavity (Oral cancer) is the 11th most common malignancy in the world. Despite the general global trend of a slight decrease in the incidence of oral cancer, tongue cancer incidence is increasing. The incidence and mortality caused by this tumor show variability according to the geographic location in which it is diagnosed. Read More

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October 2017
12 Reads

Digestive system in psoriasis: an update.

Arch Dermatol Res 2017 Nov 13;309(9):679-693. Epub 2017 Sep 13.

Dermatologikum Hamburg, Hamburg, Germany.

Psoriasis is a chronic inflammatory immune-mediated disorder associated and often coexisting with many other immune-related clinical conditions including those affecting the gastrointestinal tract. Data obtained from the reviewed literature suggest an association between psoriasis and pathologies of the oral cavity, both psoriasis-specific lesions, as well as non-specific, such as geographic tongue or fissured tongue. These findings show the importance of thorough examination of oral mucosa in psoriatic patients. Read More

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http://dx.doi.org/10.1007/s00403-017-1775-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648743PMC
November 2017
45 Reads

Lingual microbiota profiles of patients with geographic tongue.

J Oral Microbiol 2017 27;9(1):1355206. Epub 2017 Jul 27.

Department of Infectious Diseases, Institute of Biomedicine and Department of Oncology, Institute of Clinical Sciences; The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Geographic tongue (GT) is an oral mucosal lesion that affects the tongue. The association between GT and the bacterial colonization profiles of the tongue is not clear. Lingual swabs were collected from lesion sites and healthy sites of 35 patients with GT (19 males and 16 females; M = 54. Read More

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http://dx.doi.org/10.1080/20002297.2017.1355206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560410PMC
July 2017
7 Reads

Geographic tongue: assessment of peripheral nerve status, Langerhans cell, and HLA-DR expression.

Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Oct 7;124(4):371-377.e1. Epub 2017 Jun 7.

Private practice, Toronto, Ontario, Canada.

Objectives: The objectives of this study were to determine whether geographic tongue (GT) is an antigen-driven condition by assessing Langerhans cell numbers and the expression of human leukocyte antigen (HLA)-DP, -DQ, and -DR in the epithelium of GT and to assess peripheral nerve status for any possible damage/injury association by quantifying neurite area in connective tissue in GT.

Study Design: Randomly selected samples of GT were examined by using routine immunoperoxidase staining methods to S100 protein, neurofilament, CD1a, and HLA class II. The Student t test and Mann-Whitney U test were used to assess statistical significance. Read More

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http://dx.doi.org/10.1016/j.oooo.2017.05.516DOI Listing
October 2017
8 Reads

Geographic Tongue.

Am J Med 2017 Dec 14;130(12):e533-e534. Epub 2017 Jul 14.

Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1016/j.amjmed.2017.06.016DOI Listing
December 2017
4 Reads

Oral mucosal lesions in teenagers: a cross-sectional study.

Ital J Pediatr 2017 May 31;43(1):50. Epub 2017 May 31.

Dental School, Pediatric Dentistry Department, University of Brescia, P.le Spedali Civili, 1, 25123, Brescia, Italy.

Background: Adolescence is a period of transition to adulthood. Little is known about oral mucosal lesions (OMLs) in teenagers, in which the emergence of new habits, unfamiliar to children, could affect the type of lesions. The aim of this study was to evaluate the distribution of oral mucosal lesions (OMLs) in a wide sample of adolescents. Read More

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http://dx.doi.org/10.1186/s13052-017-0367-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452358PMC
May 2017
20 Reads

Acrodermatitis of Hallopeau and erosive oral mucositis successfully treated with secukinumab.

Authors:
Jennifer A Baron

JAAD Case Rep 2017 May 14;3(3):215-218. Epub 2017 Apr 14.

Private Practice, San Jose, California.

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http://dx.doi.org/10.1016/j.jdcr.2017.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394207PMC
May 2017
18 Reads

National Database Analysis of Single-Level versus Multilevel Sleep Surgery.

Otolaryngol Head Neck Surg 2017 05 21;156(5):955-961. Epub 2017 Mar 21.

6 University of Southern California, Los Angeles, California, USA.

Objective Recent evidence suggests that multilevel sleep surgery improves outcomes when compared with palate surgery alone for most patients. The study objective was to compare demographic and outcomes data for palate surgery (uvulopalatopharyngoplasty [UPPP]) alone versus multilevel surgery through a national insurance claims database. Study Design Retrospective cohort study. Read More

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http://dx.doi.org/10.1177/0194599817696503DOI Listing
May 2017
1 Read

Maternal genetic backgrounds contribute to the genetic susceptibility of tongue cancer patients in Hunan, central of China.

Mitochondrial DNA A DNA Mapp Seq Anal 2018 04 16;29(3):347-352. Epub 2017 Feb 16.

a Key Laboratory of Genetics and Birth Health of Hunan Province , Family Planning Institute of Hunan Province , Changsha , Hunan Province , China.

Mitochondrial DNA (mtDNA) mutations played crucial roles on affecting the susceptibility to cancer. In this study, to investigate whether mitochondrial DNA mutations contributed to the genetic susceptibility of Chinese tongue cancer patients, mtDNA control regions of 105 Chinese tongue cancer patients were amplified and sequenced, the mutations were recorded by comparing with the revised Cambridge Reference Sequence (rCRS), which were attributed to certain mtDNA haplogroups based on the specific variations motif of each patients. The Miao Chinese group (a Chinese ethnic minority) from surrounding region has no essential difference with tongue cancer group, which was taken as the matched control group with principal component analysis by taking the haplogroups frequency of 105 tongue cancer individuals and 354 healthy individuals of eight groups from the similar geographic regions as input factors. Read More

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https://www.tandfonline.com/doi/full/10.1080/24701394.2016.1
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http://dx.doi.org/10.1080/24701394.2016.1278539DOI Listing
April 2018
10 Reads

Oral mucosal changes induced by anticancer targeted therapies and immune checkpoint inhibitors.

Support Care Cancer 2017 05 22;25(5):1713-1739. Epub 2017 Feb 22.

Oral Medicine Department, Institut Claudius Regaud, Institut Universitaire du cancer Toulouse-Oncopole, 1 avenue Irène Joliot-Curie, 31059, Toulouse Cedex, France.

Development of biological targeted therapies and immune checkpoint inhibitors has redefined the treatment for many cancers; however, the increasing use of new protocols has led to physicians observing a new spectrum of toxicities. To date, oral adverse events induced by these new anticancer therapies have been mainly reported using nonspecific terminology ("stomatitis," "mucosal inflammation," "mucositis") and remain poorly characterized, with the exception of mammalian target of rapamycin (mTOR) inhibitor-associated stomatitis. Oral toxicities of targeted therapies often display very characteristic features which clearly differ from classic oral injuries observed with cytotoxic chemotherapy and/or radiotherapy. Read More

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http://dx.doi.org/10.1007/s00520-017-3629-4DOI Listing
May 2017
27 Reads

Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis.

Int J Dermatol 2017 Apr 10;56(4):421-427. Epub 2017 Feb 10.

Postgraduate Program in Pathology, School of Medicine, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.

Background: Few studies have examined the clinical features of geographic tongue (GT), an inflammatory lesion, making diagnosis and the investigation of oral psoriasis difficult.

Purpose: To investigate the clinical features of GT to facilitate its identification and understand its relationship with psoriasis.

Methods: A total of 96 participants diagnosed with GT underwent stomatological and dermatological examinations. Read More

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http://dx.doi.org/10.1111/ijd.13460DOI Listing
April 2017
16 Reads

Salivary levels of interleukin-8 and growth factors are modulated in patients with geographic tongue.

Oral Dis 2017 Sep 24;23(6):757-762. Epub 2017 Mar 24.

Department of Oral Medicine and Pathology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Objectives: The aim of the study was to determine the levels of salivary epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) as well as interleukin-8 (IL-8) in patients with geographic tongue (GT), as compared to control subjects.

Methodology: An enzyme-linked immunosorbent assay was used to measure the levels of IL-8, EGF and VEGF in whole saliva samples collected from 34 patients with GT and 38 control subjects. The patients and controls were grouped and matched according to age, gender and the presence of systemic diseases, which are factors that may influence the levels of salivary biomarkers. Read More

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http://doi.wiley.com/10.1111/odi.12654
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http://dx.doi.org/10.1111/odi.12654DOI Listing
September 2017
3 Reads

Autoimmune Disease Manifestations in the Oral Cavity.

Surg Pathol Clin 2017 Mar 28;10(1):57-88. Epub 2016 Dec 28.

Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida, 1395 Center Drive, Gainesville, FL 32610, USA.

Immune-related disorders of the oral cavity may occur as primary disease process, secondary to systemic disease or neoplasm, or as a reaction to medications and other agents. The entities represented within this group may vary significantly by severity, clinical presentation, microscopic presentation, and special testing results. The selected immune-related conditions of the oral cavity in this article are categorized and presented by their prototypical tissue reaction patterns: vesiculobullous, including acantholytic and subepithelial separation; psoriasiform; spongiotic; and lichenoid reaction patterns. Read More

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http://dx.doi.org/10.1016/j.path.2016.11.001DOI Listing
March 2017
4 Reads

T-Helper 17 Cell Cytokine Responses in Lyme Disease Correlate With Borrelia burgdorferi Antibodies During Early Infection and With Autoantibodies Late in the Illness in Patients With Antibiotic-Refractory Lyme Arthritis.

Clin Infect Dis 2017 Apr;64(7):930-938

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, and.

Background: Control of Lyme disease is attributed predominantly to innate and adaptive T-helper 1 cell (TH1) immune responses, whereas the role of T-helper 17 cell (TH17) responses is less clear. Here we characterized these inflammatory responses in patients with erythema migrans (EM) or Lyme arthritis (LA) to elucidate their role early and late in the infection.

Methods: Levels of 21 cytokines and chemokines, representative of innate, TH1, and TH17 immune responses, were assessed by Luminex in acute and convalescent sera from 91 EM patients, in serum and synovial fluid from 141 LA patients, and in serum from 57 healthy subjects. Read More

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http://dx.doi.org/10.1093/cid/cix002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850331PMC
April 2017
13 Reads

The Journey of "Geographic Atrophy" through Past, Present, and Future.

Ophthalmologica 2017 12;237(1):11-20. Epub 2017 Jan 12.

Department of Ophthalmology, University of Bonn, Bonn, Germany.

"Geographic atrophy" is a concise term that has been firmly established for the description of the end-stage manifestation of nonexudative age-related macular degeneration (AMD). "Geographic lesions" resembling sharply demarcated continents on a map have been originally described in the German literature in 1854 (landkartenartiger/inselförmiger Zungenfratt) for a manifestation later called "geographic tongue" in English. In 1970, Gass was the first to describe "geographic areas of atrophy" in "senile macular choroidal degeneration. Read More

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http://dx.doi.org/10.1159/000455074DOI Listing
March 2017
10 Reads

Mutations in IL36RN are associated with geographic tongue.

Hum Genet 2017 02 29;136(2):241-252. Epub 2016 Nov 29.

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.

Geographic tongue (GT) is a benign inflammatory disorder of unknown etiology. Epidemiology and histopathology in previous studies found that generalized pustular psoriasis (GPP) is a factor associated with GT, but the molecular mechanism remains obscure. To investigate the mechanism of GT, with and without GPP, three cohorts were recruited to conduct genotyping of IL36RN, which is the causative gene of GPP. Read More

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http://dx.doi.org/10.1007/s00439-016-1750-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258799PMC
February 2017
12 Reads
4.820 Impact Factor

Host and clinical aspects in patients with benign migratory glossitis.

Arch Oral Biol 2017 Jan 26;73:259-268. Epub 2016 Oct 26.

Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.

Objective: Investigate the association of clinical, cytological and genetic characteristics with benign migratory glossitis (BMG).

Study Design: Sample consisted of 175 patients, 44 with BMG and 131 control patients. Clinical examination and DMFT index were assessed. Read More

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http://dx.doi.org/10.1016/j.archoralbio.2016.10.027DOI Listing
January 2017
6 Reads

The single-species metagenome: subtyping core genome sequences from shotgun metagenomic data.

PeerJ 2016 18;4:e2571. Epub 2016 Oct 18.

Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.

In this study we developed a genome-based method for detecting subtypes from metagenome shotgun sequence data. We used a binomial mixture model and the coverage counts at >100,000 known SNP (single nucleotide polymorphism) sites derived from prior comparative genomic analysis to estimate the proportion of 40 subtypes in metagenome samples. We were able to obtain >87% sensitivity and >94% specificity at 0. Read More

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http://dx.doi.org/10.7717/peerj.2571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075713PMC
October 2016
11 Reads