592,739 results match your criteria Genital Warts


Perineal prevention and protection in obstetrics: CNGOF Clinical Practice Guidelines.

J Gynecol Obstet Hum Reprod 2018 Dec 12. Epub 2018 Dec 12.

Obs/Gyn, Epidemiologist. INSERM CIC1402, Université de Poitiers, CHU de Poitiers, France. Electronic address:

Introduction: The objective of these clinical practice guidelines was to analyse all of the interventions during pregnancy and childbirth that might prevent obstetric anal sphincter injuries (OASIS) and postnatal pelvic floor symptoms.

Material And Methods: These guidelines were developed in accordance with the methods prescribed by the French Health Authority (HAS).

Results: A prenatal clinical examination of the perineum is recommended for women with a history of Crohn's disease, OASIS, genital mutilation, or perianal lesions (professional consensus). Read More

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December 2018

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9.

Nat Commun 2018 Dec 14;9(1):5319. Epub 2018 Dec 14.

Murdoch Children's Research Institute, Melbourne, 3052, VIC, Australia.

Disorders of sex development (DSDs) are conditions affecting development of the gonads or genitalia. Variants in two key genes, SRY and its target SOX9, are an established cause of 46,XY DSD, but the genetic basis of many DSDs remains unknown. SRY-mediated SOX9 upregulation in the early gonad is crucial for testis development, yet the regulatory elements underlying this have not been identified in humans. Read More

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December 2018

A trivalent gC2/gD2/gE2 vaccine for herpes simplex virus generates antibody responses that block immune evasion domains on gC2 better than natural infection.

Vaccine 2018 Dec 12. Epub 2018 Dec 12.

Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, United States. Electronic address:

Vaccines for prevention and treatment of genital herpes are high public health priorities. Our approach towards vaccine development is to focus on blocking virus entry mediated by herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) and to prevent the virus from evading complement and antibody attack by blocking the immune evasion domains on HSV-2 glycoproteins C (gC2) and E (gE2), respectively. HSV-2 gC2 and gE2 are expressed on the virion envelope and infected cell surface where they are potential targets of antibodies that bind and block their immune evasion activities. Read More

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December 2018

Primary signet-ring stromal tumour of the testis: case report with literature review.

APMIS 2019 Jan;127(1):45-49

Institute of Pathology, University of Göttingen, Göttingen, Germany.

Primary signet-ring stromal tumour of the testis (PSRSTT) is a very rare type of primary testicular tumour, which is not actually mentioned in the current WHO categorization of tumours of the male genital organs. In this case we report about histologically and immunohistochemically features of this rare tumour. In the present case, PSRTT was found in the orchiectomy preparation of a 69-year-old man with painless swelling of his left testicle. Read More

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January 2019

African-American parents' and daughters' beliefs about HPV infection and the HPV vaccine.

Public Health Nurs 2018 Dec 11. Epub 2018 Dec 11.

Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia.

Objective: To increase our understanding about the health beliefs of African-American parents and their daughters toward HPV infection and HPV vaccine acceptance.

Methods: The Health Belief Model was used as a guiding framework. Principles of grounded theory, theoretical sampling, and constant comparison analysis were used to qualitatively analyze data generated from personal interviews of African-American parents (n = 30) and their 12- to 17-year-old daughters (n = 34). Read More

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December 2018

Two's company, three's a crowd: co-occurring pollinators and parasite species in Breynia oblongifolia (Phyllanthaceae).

BMC Evol Biol 2018 Dec 14;18(1):193. Epub 2018 Dec 14.

Hawkesbury Institute for the Environment, Hawkesbury Campus, Western Sydney University, Science Rd, Richmond, NSW, 2753, Australia.

Background: Obligate pollination mutualisms (OPMs) are specialized interactions in which female pollinators transport pollen between the male and female flowers of a single plant species and then lay eggs into those same flowers. The pollinator offspring hatch and feed upon some or all of the developing ovules pollinated by their mothers. Strong trait matching between plants and their pollinators in OPMs is expected to result in reciprocal partner specificity i. Read More

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December 2018

Vaginoplasty and creating labia minora in children with disorders of sex development.

Int Urol Nephrol 2018 Dec 13. Epub 2018 Dec 13.

Department of Visceral Surgery, Faculty of Medicine, Children's Hospital Canastel, University of Oran, Oran, Algeria.

Purpose: To report current results of vaginoplasty using the mucosa of the prepuce, and creating labia minora by penile skin in children with disorders of sex development (DSD).

Methods: In 10 years, we have performed 22 vaginoplasties using the described technique of vaginoplasty, 21 patients with 46, XX DSD and 1 ovotesticular DSD. The assessment of the results of this technique of vaginoplasty was undertaken in several stages: (a) The evaluation of the cosmetic result. Read More

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December 2018

Similarities and Differences Between Staphylococcal and Streptococcal Toxic Shock Syndromes in Children: Results From a 30-Case Cohort.

Front Pediatr 2018 28;6:360. Epub 2018 Nov 28.

Centre National de Référence des Staphylocoques, Institut des Agents Infectieux, Centre de Biologie et de Pathologie Nord, Hospices Civils de Lyon, Lyon, France.

Toxic shock syndromes (TSS) are severe shocks due to staphylococcal or streptococcal infection that require specific treatments. The early recognition of these shocks is crucial to improve their outcomes. The primary objective of this study was to compare characteristics and outcomes of staphylococcal and streptococcal TSS in children, in order to identify putative early clinical diagnostic criteria. Read More

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November 2018

IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment.

Oncoimmunology 2019 6;8(1):e1515058. Epub 2018 Sep 6.

Vaccine and Immunotherapy Center, The Wistar Institute, Philadlephia, PA, USA.

Ovarian cancer is frequently diagnosed as peritoneal carcinomatosis. Unlike other tumor locations, the peritoneal cavity is commonly exposed to gut-breaching and ascending genital microorganisms and has a unique immune environment. IL-33 is a local cytokine that can activate innate and adaptive immunity. Read More

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September 2018

Intestinal-type adenocarcinoma of the vagina: clinico-pathologic features of a common tumor with a rare localization.

Pathologica 2018 Sep;110(2):92-95

Department of Medical and Surgical Sciences and Advanced Technologies, G.F. Ingrassia, Azienda Ospedaliero-Universitaria "Policlinico-Vittorio Emanuele", Anatomic Pathology Section, School of Medicine, University of Catania, Italy.

Intestinal-type adenocarcinoma is a rare primary vaginal carcinoma and considerably more uncommon than metastatic lesions which represent the most frequent malignancy at this anatomic site. Among all malignant tumors, colorectal, breast and female genital tract carcinomas have the tendency to metastasize to the vagina.

As morphologic and immunohistochemical features of intestinal-type adenocarcinoma occurring primarily in the vagina are not specific, clinical and radiologic information is crucial to exclude a metastatic lesion. Read More

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September 2018

[Microbiological analysis of the maternal genital tract and umbilical cord blood and its association with neonatal damage].

Rev Argent Microbiol 2018 Dec 9. Epub 2018 Dec 9.

Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Facultad de Farmacia y Bioquímica, Hospital de Clínicas José de San Martín, Universidad de Buenos Aires, Córdoba, CABA, Argentina. Electronic address:

The etiology leading to neonatal damage is multifactorial, being genital infections one of the causes. The objective of the study was to identify microorganisms of the maternal genital tract that are associated with neonatal damage, in order to prevent future perinatal complications. Seven hundred and eleven pregnant patients attended their prenatal control during the period January 2010-July 2013. Read More

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December 2018

Preference of specimen collection methods for human papillomavirus detection for cervical cancer screening: a cross-sectional study of high-risk women in Mombasa, Kenya.

Reprod Health 2018 Dec 12;15(1):206. Epub 2018 Dec 12.

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Objectives: Self-collection of genital specimens for high-risk types of human papillomavirus (hrHPV) detection may increase cervical cancer screening uptake. We hypothesized that women would prefer self-collection to clinician-collection of genital specimens. To test this hypothesis, and women's preference between two different self-collection approaches, a total of 199 women were enrolled in a cross-sectional study in Mombasa, Kenya. Read More

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December 2018

Comparison of rRNA-based and DNA-based nucleic acid amplifications for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Ureaplasma urealyticum in urogenital swabs.

BMC Infect Dis 2018 Dec 12;18(1):651. Epub 2018 Dec 12.

Department of Infection Control, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, People's Republic of China.

Background: Nucleic acid amplification tests (NAAT) are well-accepted in diagnosis and surveillance of sexually infectious pathogens worldwide. However, performance differences between a RNA-based NAAT and DNA-based NAAT are rarely reported. This study compares the performances of the RNA-based SAT (simultaneous amplification and testing) assay and the DNA-based quantitative real-time polymerase chain reaction (qPCR) assay. Read More

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December 2018

Discussing sexuality in the field of plastic and reconstructive surgery: a national survey of current practice in the Netherlands.

Eur J Plast Surg 2018 18;41(6):707-714. Epub 2018 Aug 18.

1Department of Plastic Reconstructive and Hand Surgery, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, Netherlands.

Background: Patient-reported outcomes have become increasingly important to assess the value of surgical procedures. Sexual function is a proven important constituent of quality of life, but is often overlooked by health care professionals. We aim to investigate to what extent plastic surgeons address or discuss issues concerning sexuality with their patients, and if there is a need for improvement. Read More

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Spirorchis spp. (Digenea: Schistosomatoidea) infecting map turtles (Cryptodira: Emydidae: Graptemys spp.) in southeastern North America: A new species, molecular phylogenies, and key to species.

Syst Parasitol 2018 Dec 6. Epub 2018 Dec 6.

Aquatic Parasitology Laboratory, School of Fisheries, Aquaculture & Aquatic Sciences, College of Agriculture, Auburn University, 203 Swingle Hall, Auburn, AL, 36849, USA.

Black-knobbed map turtles (Graptemys nigrinoda Cagle) and Alabama map turtles (Graptemys pulchra Baur) were infected with several blood flukes in Alabama (southeastern North America). Spirorchis paraminutus Roberts & Bullard n. sp. Read More

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December 2018

Mullerian adenosarcomas of the uterine cervix with sarcomatous overgrowth.

Curr Probl Cancer 2018 Nov 30. Epub 2018 Nov 30.

Clinic of Obstetrics and Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia.

Mullerian adenosarcoma with sarcomatous overgrowth (MASO) of the uterine cervix is an extremely rare variant of adenosarcoma of the genital tract associated with aggressive clinical course. We searched the PubMed and Medline databases for MASO of the cervix and we identified and reviewed eleven cases published between years 2004 and 2017. The most common clinical picture includes abnormal vaginal bleeding, postcoital bleeding, pelvic pain and foul-smelling vaginal discharge. Read More

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November 2018
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Tuberculosis and HIV co-infection; the deadly duos in vulva.

Indian J Tuberc 2018 Oct 22;65(4):277-279. Epub 2018 May 22.

Professor, Department of Dermatology and Venereology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal.

Human Immunodeficiency Virus induced immune suppression leads the way for various infections with tuberculosis being the most common. Tuberculosis of the vulva is an extremely rare entity and is seen in only 1-2% of genital TB with increased risk in HIV co-infection. The co-infection places an immense burden on health care systems and poses particular diagnostic & therapeutic challenges with high mortality and morbidity. Read More

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October 2018
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Two-Team Surgical Approach to Improve Retroperitoneal Nerve Identification in the Treatment of Groin Pain.

Ann Plast Surg 2019 Jan;82(1):82-84

Greater Baltimore Medical Center, Towson, Maryland.

Background: An estimated 700,000 groin hernia repairs are performed in the United States each year. Studies have shown that up to 50% of patients who undergo groin hernia repair are affected by persistent pain beyond the first few days after surgery. At 2 to 5 years after either open or laparoscopic, mesh or without mesh, 10% to 12% of these patients will have persistent and disabling pain. Read More

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January 2019
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A report of human papilloma virus-16 associated vaginal carcinoma after thirty-two years of successful radiation therapy for cervical cancer.

Virusdisease 2018 Dec 3;29(4):537-539. Epub 2018 Aug 3.

1Department of Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104 Karnataka India.

Once the recommended 5-year recurrence-free follow-up is achieved for cervical cancers regular annual pelvic examination is mandatory. The main aim of presenting this short report is to emphasize the difficulties in the collection and interpretation of cytology samples from stenosed cervix or vault after pelvic irradiation. Radiotherapy can induce changes in the cellular morphology which may persist for many years. Read More

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December 2018

Screening of Cervical Cancer with Self-Collected Cervical Samples and Next-Generation Sequencing.

Dis Markers 2018 14;2018:4826547. Epub 2018 Nov 14.

Department of Gynecologic Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Cervical cancer is the second leading cause of death in female genital malignancies. Persistent infection with high-risk HPV is closely related to cervical intraepithelial neoplasia (CIN). Wide-scale HPV screening has already been implemented in developed countries. Read More

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November 2018

Lipid-Modified Azurin of Is Not Surface Exposed and Does Not Interact With the Nitrite Reductase AniA.

Front Microbiol 2018 27;9:2915. Epub 2018 Nov 27.

Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR, United States.

Lipid-modified cupredoxin azurin (Laz) is involved in electron transport in and proposed to act as an electron donor to the surface-displayed nitrite reductase AniA. We identified Laz in cell envelopes and naturally elaborated membrane vesicles in proteomic investigations focused on discovering new vaccine and therapeutic targets for this increasingly difficult to treat pathogen. Its surface exposure in suggested Laz could be a vaccine candidate for . Read More

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November 2018

The case of 17-year-old male with LEOPARD syndrome.

J Cardiol Cases 2013 Feb 4;7(2):e37-e41. Epub 2012 Dec 4.

Department of Myocardial Dysfunction and Heart Failure, B.V. Petrovsky Russian Research Centre of Surgery RAMS, 119991, Abrikosovky per, 6, Moscow, Russia.

LEOPARD syndrome is a phenotypic expression of mutations in several genes: PTPN11, RAF1, and BRAF. All these genes are responsible for Ras/MARK signaling pathway, which are important for cell cycle regulation, differentiation, growth, and aging. Mutations result in anomalies of skin, skeletal, and cardiovascular systems. Read More

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February 2013
2 Reads

Major Motivators and Sociodemographic Features of Women Undergoing Labiaplasty.

Aesthet Surg J 2018 Dec 8. Epub 2018 Dec 8.

Clinic of Obstetrics and Gynaecology, Bartin State Hospital, Bartin, Turkey.

Background: Influencing factors to decide for labiaplasty are evolving and show diversity among different settings and countries. Updated underlying motivators may assist in the clinical decision-making and assessing outcomes from the patients' perspective.

Objective: Herein, the main motivators of women undergoing labiaplasty and sociodemographic features are discussed. Read More

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December 2018
2 Reads

[Prevalence of genital Chlamydia trachomatis infection in women attending in the National Institute of Perinatology from Mexico City].

Rev Chilena Infectol 2018 Aug;35(4):371-376

Laboratorio de Biología Molecular, Departamento de Infectología, Instituto Nacional de Perinatología, Mexico.

Background: Endocervical infection by Chlamydia trachomatis is considered one of the leading causes of infertility worldwide. During pregnancy, it can lead to serious complications such as premature rupture of membranes and premature births.

Aim: To determine the prevalence of genital infection by C. Read More

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Complete Genome Sequence of Herpes Simplex Virus 2 Strain 333.

Microbiol Resour Announc 2018 Sep 6;7(9). Epub 2018 Sep 6.

Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid), Madrid, Spain.

Herpes simplex virus 2, or human herpesvirus 2, is a ubiquitous human pathogen that causes genital ulcerations and establishes latency in sacral root ganglia. We fully sequenced and manually curated the viral genome sequence of herpes simplex virus 2, strain 333 using Pacific Biosciences and Illumina sequencing technologies. Read More

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September 2018

Complete Genome Sequences of Six Novel Macaca mulatta Papillomavirus Types Isolated from Genital Sites of Rhesus Monkeys in Hong Kong SAR, China.

Microbiol Resour Announc 2018 Dec 6;7(22). Epub 2018 Dec 6.

Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

The complete genomes of six Macaca mulatta papillomavirus types isolated from genital sites of rhesus monkeys were characterized, and less than 72% identity with the complete L1 genes of known papillomaviruses was found. Macaca mulatta papillomavirus type 2 (MmPV2), MmPV3, and MmPV6 cluster into the genus , and MmPV4, MmPV5, and MmPV7 cluster into the genus . Read More

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December 2018

Myeloid Cells in Intact Human Cervical Explants Capture HIV and Can Transmit It to CD4 T Cells.

Front Immunol 2018 23;9:2719. Epub 2018 Nov 23.

Program in Cellular and Molecular Medicine, Department of Pediatrics, Harvard Medical School, Boston Children's Hospital, Boston, MA, United States.

The importance of myeloid cells in HIV transmission in the female genital tract is uncertain. Because it is difficult to study the early events in HIV transmission in humans, most of our knowledge is based on animal models of SIV infection in Rhesus macaques and more recently HIV infection in humanized mice. However, these models may not accurately recapitulate transmission in the human genital tract. Read More

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November 2018

Revision of the genus Zeller, 1839, a challenging taxonomic tightrope of species delimitation (Lepidoptera, Gelechiidae).

Zookeys 2018 29(800):1-278. Epub 2018 Nov 29.

Zoological Museum, Natural History Museum of Denmark, Universitetsparken 15, DK-2100 Copenhagen, Denmark Zoological Museum, Natural History Museum of Denmark Copenhagen Denmark.

The taxonomy of the Palearctic genus Zeller, 1839 (Lepidoptera, Gelechiidae) is revised, based on external morphology, genitalia and DNA barcodes. An integrative taxonomic approach supports the existence of 85 species which are arranged in 24 species groups (disputed taxa from other faunal regions are discussed). Morphology of all species is described and figured in detail. Read More

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November 2018

Systematics of the new genus Chen, Zhang & Li with descriptions of four new species (Lepidoptera, Crambidae, Pyraustinae).

Zookeys 2018 28(799):115-151. Epub 2018 Nov 28.

College of Life Sciences, Nankai University, Tianjin 300071, China Nankai University Tianjin China.

The new genus is proposed for three known species, (Warren, 1896), , (Snellen, 1890), , and (Lederer, 1863), and four new species, , , , and from the Oriental Region. An identification key is provided for all species. The habiti and genitalia of all species are figured. Read More

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November 2018

Review of the Neotropical genus with descriptions of three new species-group taxa (Hemiptera, Heteroptera, Pentatomidae).

Zookeys 2018 15(796):347-395. Epub 2018 Nov 15.

Florida State Collection of Arthropods, 2606 S. Dundee St., 33629 Tampa, FL, USA Florida State Collection of Arthropods Tampa United States of America.

The genus Bergroth, 1911 (Hemiptera: Heteroptera: Pentatomidae: Pentatominae: Chlorocorini) is redescribed and five species-group taxa are recognized, keyed, their diagnostic characters illustrated, and the distribution reviewed. Among the five taxa, two species and one subspecies are recognized as new: Bergroth, 1911 (Brazil, Ecuador, French Guiana, Guyana, Peru, Suriname), (Belize, Costa Rica, Guatemala, Mexico, Panama), (French Guiana), Becker & Grazia-Vieira, 1971 (Bolivia, Brazil, Ecuador, Peru), and (Guyana). The structure of the male genital capsule was found to be the only reliable character for identifying species-group taxa. Read More

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November 2018

[State of the venous outflow from the small pelvis after surgical correction of pelvioperineal reflux].

Angiol Sosud Khir 2018 ;24(4):90-94

Chair of Faculty Surgery #1, Therapeutic Department, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia.

Objective: The study was aimed at assessing the venous outflow from the small pelvis after surgical correction of pelvioperineal reflux with the use of reference methods of examination.

Patients And Methods: We examines a total of 43 female patients (aged 41.5±5. Read More

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January 2018

Real-life experience with ceftolozane/tazobactam in patients with hematologic malignancy and infection: a case-control study.

Antimicrob Agents Chemother 2018 Dec 10. Epub 2018 Dec 10.

Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain.

Background: We present our experience in patients with hematologic malignancy and infection treated with ceftolozane-tazobactam.

Materials/methods: We performed a single-center case-control study including all patients with hematologic malignancy and infection treated with ceftolozane-tazobactam (study group) and compared them with similar patients not treated with ceftolozane-tazobactam (control group) to assess safety and efficacy.

Results: Nineteen cases and 38 controls were analyzed. Read More

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December 2018

Problematic molecular diagnosis of HSV-1 infection due to a single nucleotide polymorphism in the US7 gene.

J Clin Virol 2018 Dec 3;110:42-44. Epub 2018 Dec 3.

Virology Laboratory, Centre Hospitalier Universitaire de Nice, 151 Route Saint Antoine Ginestiere, 06202 Nice Cedex 3, France. Electronic address:

Background: HSV-1 infection is very common worldwide and can be associated with severe medical conditions such as encephalitis and neonatal herpes. Current diagnosis relies heavily on molecular assays targeting the viral genome. One of the pitfalls of these assays is genetic variability, as viral polymorphisms located in the target region can impair the detection of HSV-1. Read More

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December 2018

Genital morphology and copulatory behavior in triatomine bugs (Reduviidae: Triatominae).

Arthropod Struct Dev 2018 Dec 6. Epub 2018 Dec 6.

CONACYT-Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Avenida Universidad 655, Col. Santa María Ahuacatitlán, Cerrada Los Pinos y Caminera, 62100, Cuernavaca, Morelos, México. Electronic address:

Triatomines (Heteroptera: Reduviidae) include around 139 species, widely known as vectors of Chagas disease. Our aim is to review the existing knowledge of the genital morphology and sexual behavior and provide some functional analysis of these traits in triatomines. A complex set of traits comprise genitalia and these are highly variable among species. Read More

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December 2018

Challenges and Opportunities in Adolescent Gynecology Patients with Surgically-Treated Congenital and Acquired Anomalies: Transition of Care from Pediatric to Adult Surgery.

J Pediatr Adolesc Gynecol 2018 Dec 5. Epub 2018 Dec 5.

Department of obstetrics and gynecology, university of Louisville, USA.

The transition from adolescence to young adulthood in patients with reproductive health care needs such as disorders of sexual development (DSDs) and congenital anomalies is a complex process occurring over several years. The transition process for these patients has is still poorly understood. The patients with DSDs and reproductive issues have specific and unique issues regarding timing of disclosure of diagnosis, genital examinations, gonadectomy, vaginal treatments, surgical procedures hormone replacement therapy, use of long term medication and potential cancer screening. Read More

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December 2018

Wing morphometric analysis of forensically important flesh flies (Diptera: Sarcophagidae) in Thailand.

Acta Trop 2018 Dec 7;190:312-319. Epub 2018 Dec 7.

Department of Parasitology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:

Flesh flies are insects of forensic importance as the larvae associated with human remains can be used to estimate a minimum post-mortem interval (PMI) in most cases. And, because life-history traits can vary across species, correct identification is a mandatory step before being used as evidence. Adult flesh flies are extremely similar in general appearance, which causes difficulty in species identification as it is largely based on the morphology of the male genitalia; this also makes it difficult to identify females. Read More

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December 2018

Setting the record straight: The nosology of tardive syndromes.

Parkinsonism Relat Disord 2018 Nov 28. Epub 2018 Nov 28.

Department of Neurology, Loma Linda University Medical Center, Loma Linda, CA, USA.

We propose the use of the term tardive dyskinesia to refer to the original description of repetitive and complex oral-buccal-lingual (OBL) movements and the analogous repetitive movements of the limbs, trunk, or pelvis. The term tardive syndrome is an umbrella term to be used to refer to the spectrum of all persistent hyperkinetic, hypokinetic, and sensory phenomenologies resulting from chronic dopamine receptor blocking agent (DRBA) exposure. TD is a type of TS. Read More

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November 2018
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Case Report: Cervicovaginal Co-Colonization with and in Association with an Intrauterine Device.

Am J Trop Med Hyg 2018 Dec 10. Epub 2018 Dec 10.

Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.

Amoebic trophozoites were identified in the cervicovaginal smear of a U.S. patient without travel history at the time of intrauterine device (IUD) removal. Read More

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December 2018
1 Read

HPV vaccines and lupus: current approaches towards preventing adverse immune cross-reactivity.

Expert Rev Vaccines 2018 Dec 10. Epub 2018 Dec 10.

c Department of Medicine B and Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat-Gan; Sackler Faculty of Medicine , Tel-Aviv University , Tel-Aviv , Israel.

Introduction: If not properly treated, human papillomavirus (HPV) infection may evolve from a common sexually transmitted disease to genital warts and cervical cancer. Various prophylactic HPV vaccines (HPVv), approved to reduce the incidence of the infection, have been found to be effective and safe; however, accounts of post-vaccination autoimmune phenomena, including systemic lupus erythematosus (SLE), have been reported in genetically susceptible individuals. Areas covered: Infectious agents play a role in breaking the immunologic tolerance to self-antigens, resulting in autoimmune events. Read More

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December 2018

Young key affected population in Myanmar: are there any challenges in seeking information and care for HIV/sexually transmitted infections and reproductive health?

F1000Res 2018 21;7:1515. Epub 2018 Sep 21.

Department of Medical Research, Ministry of Health and Sports, Yangon, 11191, Myanmar.

Unmet needs and barriers in seeking HIV/STI and RH information and care are present especially among young key affected population (YKAP). Therefore, the study was conducted to determine the health seeking behaviors of YKAP regarding HIV/STI and RH, and challenges in seeking health information and care. A cross-sectional, mixed-methods study was conducted at two large cities in Myanmar. Read More

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September 2018
2 Reads

Aggressive Angiomyxoma: A Rare Tumor of Male Pelvic Cavity.

Acta Med Port 2018 Nov 30;31(11):693-696. Epub 2018 Nov 30.

Department of General Surgery. Ankara University School of Medicine. Ankara. Turkey.

Aggressive angiomyxoma is an uncommon, benign, slow-growing, and locally infiltrative soft tissue neoplasm which is located primarily in the genital region and pelviperineal interstitial tissue of female patient in the fourth decade of life. Its occurrence in male patients is even more unusual and commonly appears at a later age. The mainstay of treatment typically involves surgical excision with tumor-free margins, and despite complete resection, local recurrences are common. Read More

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November 2018
3 Reads

Mutilating genital aphthous ulceration causing perforation in two women.

Clin Exp Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Dermatology, University of Medical Sciences, Haydarpaşa Numune Training and Research Hospital, Istanbul, 34662, Turkey.

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December 2018

The incidence and predictors of gynecologic malignancies among postmenopausal patients with endometrial fluid collection.

Authors:
Zhe Li Lei Li

Arch Gynecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Shuaifuyuan No 1, Dongcheng District, Beijing, China.

Objective: To investigate the incidence and predictors of gynecologic malignancies among postmenopausal patients with endometrial fluid collection (EFC).

Methods: All patients with EFC diagnosed by transvaginal sonography (TVS) were retrospectively reviewed if they had undergone biopsy of the endometrium from January 2008 to January 2016 in a tertiary teaching hospital. Follow-up ended in June 2017. Read More

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December 2018
1 Read
1.279 Impact Factor

Human papillomavirus 16 E2 regulates keratinocyte gene expression relevant to cancer and the viral life cycle.

J Virol 2018 Dec 5. Epub 2018 Dec 5.

VCU Philips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Department of Oral and Craniofacial Molecular Biology, Richmond, VA 23298, USA.

Human papillomaviruses (HPV) are causative agents in ano-genital and oropharyngeal cancers. The virus must reprogram host gene expression to promote infection, and E6 and E7 contribute to this via targeting of cellular transcription factors including p53 and pRb, respectively. The HPV16 E2 protein regulates host gene expression in U2OS cells and in this study we extend these observations into TERT immortalized oral keratinocytes (NOKs) that are capable of supporting late stages of the HPV16 life cycle. Read More

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December 2018

Histidine-rich glycoprotein inhibits HIV-1 infection in a pH-dependent manner.

J Virol 2018 Dec 5. Epub 2018 Dec 5.

Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), Universidad de Buenos Aires (UBA) and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Histidine-rich glycoprotein (HRG) is an abundant plasma protein with a multidomain structure allowing its interaction with many ligands including phospholipids, plasminogen, fibrinogen, IgG antibodies, and heparan sulfate. HRG has shown to regulate different biological responses such as angiogenesis, coagulation and fibrinolysis. Here, we found that HRG almost completely abrogated the infection of GHOST, Jurkat, CD4+ T cells, and macrophages by HIV-1 at low pH (range 6. Read More

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December 2018
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Alpha shapes: determining 3D shape complexity across morphologically diverse structures.

BMC Evol Biol 2018 Dec 5;18(1):184. Epub 2018 Dec 5.

School of Science and the Environment, Manchester Metropolitan University, Manchester, M1 5GD, UK.

Background: Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To use this data to address evolutionary and ecological questions, an array of tools has been developed to conduct shape analysis and quantify topographic complexity. Here we focus particularly on shape techniques applied to irregular-shaped objects lacking clear homologous landmarks, and propose a new 'alpha-shapes' method for quantifying 3D shape complexity. Read More

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December 2018
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Human papillomaviruses' proteins with clinical utility.

J Immunoassay Immunochem 2018 Dec 5:1-10. Epub 2018 Dec 5.

a Department of Molecular Virology , Stefan S Nicolau Institute of Virology , Bucharest , Romania.

Cervical cancer, the fourth leading cause of cancer-associated deaths among women worldwide, is associated with human papilloma virus (HPV) infection. Despite the prophylactic HPV vaccination and the implementation of cervical and HPV-based screening programs, a significant increase in cervical cancer incidence is estimated by the year 2020. Thus, further development of diagnostic tools that allow detection and risk assesment in genital HPV infection is necessary. Read More

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December 2018

Lifetime Spousal Violence Victimization and Perpetration, Physical Illness, and Health Risk Behaviours among Women in India.

Int J Environ Res Public Health 2018 Dec 4;15(12). Epub 2018 Dec 4.

Department of Research & Innovation, University of Limpopo, Turfloop 0727, South Africa.

The aim of this study was to assess the association between lifetime spousal violence victimization, spousal violence perpetration, and physical health outcomes and behaviours among women in India. In the 2015⁻2016 National Family Health Survey, a sample of ever-married women (15⁻49 years) ( = 66,013) were interviewed about spousal violence. Results indicate that 29. Read More

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December 2018
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The Role of Tumor Necrosis Factor α in the Biology of Uterine Fibroids and the Related Symptoms.

Int J Mol Sci 2018 Dec 4;19(12). Epub 2018 Dec 4.

First Department of Obstetrics and Gynecology, The Center of Postgraduate Medical Education, 01-004 Warsaw, Poland.

Uterine fibroids (UFs) are the most common benign tumors of the female genital tract. The incidence of UFs has been estimated at 25⁻80% depending on selected population. The pathophysiology of UFs remains poorly understood. Read More

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December 2018
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Type of pelvic disease as a risk factor for surgical site infection in women undergoing hysterectomy.

J Minim Invasive Gynecol 2018 Nov 30. Epub 2018 Nov 30.

The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa ON, K1Y 4E9.

Study Objective: To quantify the relationship between type of benign pelvic disease and risk of surgical site infection (SSI) after hysterectomy DESIGN: Retrospective Cohort (Classification II-2) SETTING: Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) PATIENT(S): Women who underwent hysterectomy from 2006-2015 and recorded in NSQIP database INTERVENTION: None MEASUREMENTS AND MAIN RESULTS: SSI risk was compared for type of benign pelvic diseases, patient characteristics (age, race and selected comorbidities) and process of care variables (admission status, type of hysterectomy, and operative time). Among a total of 125,337 women who underwent hysterectomy, 2.48% developed SSI. Read More

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November 2018
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