7,567 results match your criteria Genital Warts

Green Tea Polyphenols Cause Apoptosis and Autophagy in HPV-16 Subgene-Immortalized Human Cervical Epithelial Cells via the Activation of the Nrf2 Pathway.

Nutr Cancer 2022 Jun 30:1-10. Epub 2022 Jun 30.

Guangzhou Medical University, Guangzhou, Guangdong Province, China.

Infection with human papillomavirus (HPV) is relatively common and certain high-risk HPV strains can induce epithelial dysplasia, increasing the risk of cervical cancer. Green tea polyphenol (GTP) preparations exhibit diverse anti-inflammatory, antioxidative, and antitumor properties In Vitro and In Vivo. Topical GTP application has been recommended as a treatment for genital warts, but the effect of GTP treatment on HPV infection and HPV-associated cancer remains to be established. Read More

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Drugs for sexually transmitted infections.


Med Lett Drugs Ther 2022 06;64(1653):97-104

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Comparative Analysis of the Incidence of Selected Sexually Transmitted Viral Infections in Poland in 2010-2015: A Retrospective Cohort Study.

J Clin Med 2022 Jun 15;11(12). Epub 2022 Jun 15.

Department of Medical Sciences, Faculty of Health Sciences, Lomza State University of Applied Sciences, 18-400 Lomza, Poland.

Sexually transmitted infections (STIs) represent a major cause of morbidity in women and men worldwide. The main aim of this study was to perform a comparative analysis of the incidence of sexually transmitted viral infections in 2010-2015 in Poland, taking into account the administrative division of the country into provinces. This was a retrospective study. Read More

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Diagnostic Pearls of Vulvar Epidermolytic Acanthoma: Case Report.

Ann Dermatol 2022 Jun 20;34(3):221-224. Epub 2022 May 20.

Department of Dermatology, UF Health Dermatology-Springhill, Gainesville, FL, United States.

Epidermolytic acanthomas (EA) are uncommon benign tumors clinically presenting as single to multiple papules. Histologically, EA display hyperkeratosis, hypergranulosis, acanthosis, and epidermal degeneration-also known as epidermolytic hyperkeratosis (EH). EA may be misdiagnosed as condyloma both clinically and histopathologically when located on the genitalia. Read More

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RG2-VLP: a Vaccine Designed to Broadly Protect against Anogenital and Skin Human Papillomaviruses Causing Human Cancer.

J Virol 2022 Jun 15:e0056622. Epub 2022 Jun 15.

Department of Pathology, Johns Hopkins Universitygrid.21107.35, Baltimore, Maryland, USA.

The family of human papillomaviruses (HPV) includes over 400 genotypes. Genus α genotypes generally infect the anogenital mucosa, and a subset of these HPV are a necessary, but not sufficient, cause of cervical cancer. Of the 13 high-risk (HR) and 11 intermediate-risk (IR) HPV associated with cervical cancer, genotypes 16 and 18 cause 50% and 20% of cases, respectively, whereas HPV16 dominates in other anogenital and oropharyngeal cancers. Read More

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Changes in the Prevalence of Human Papillomavirus Genotypes in Genital Warts Since the Introduction of Prophylactic Vaccines.

Actas Dermosifiliogr 2022 Jun 7. Epub 2022 Jun 7.

Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España.

Background And Objective: Genital warts are caused by the human papillomavirus (HPV), whose genotypes have traditionally been classified as low risk or high risk (oncogenic). The first 2 prophylactic vaccines included the most common genotypes at the time: HPV-6, HPV-11, HPV-16, and HPV-18. The aim of this study was to evaluate the prevalence of HPV types in our setting 10 years after the introduction of HPV vaccines. Read More

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Vulvar condyloma of Buschke and Löwenstein: an unusual tumour in developed countries.

BMJ Case Rep 2022 06 7;15(6). Epub 2022 Jun 7.

Gynecology and Obstetrics, Unidade Local de Saude de Matosinhos EPE, Hospital Pedro Hispano, Matosinhos, Porto, Portugal.

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Current data on the efficacy of prophylactic HPV vaccination in the primary prevention of cervical lesions.

Ceska Gynekol 2022 ;87(2):124-130

Objective: A review of current knowledge on the efficacy of HPV (human papillomavirus) HPV vaccination against pre-cancers and cervical cancer.

Methods And Results: HPV infection is probably the most common sexually transmitted disease and the cause of approximately 5% of all human cancers. Currently, three prophylactic vaccines against HPV infection are on the market: bivalent Cervarix, quadrivalent Gardasil (formerly Silgard) and nonavalent Gardasil9. Read More

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Rectal Condyloma Acuminatum.

Mayo Clin Proc 2022 Jun;97(6):1156-1157

Department of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.

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A nationwide longitudinal study on risk factors for progression of anal intraepithelial neoplasia grade 3 to anal cancer.

Int J Cancer 2022 Jun 3. Epub 2022 Jun 3.

Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.

Little is known about risk factors for progression of high-grade anal intraepithelial neoplasia (AIN) to anal squamous cell carcinoma (ASCC). In this large, population-based study, we assess the role of factors related to immune status for the risk of ASCC among individuals from the general population with a diagnosis of AIN3. Individuals diagnosed with AIN3 during 1985-2016 were identified in the Danish Pathology Registry and followed for subsequent development of ASCC. Read More

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Human Papillomavirus Infection and the Risk of Erectile Dysfunction: A Nationwide Population-Based Matched Cohort Study.

J Pers Med 2022 Apr 27;12(5). Epub 2022 Apr 27.

Department of Orthopedics, Taichung Veterans General Hospital, Taichung 40402, Taiwan.

Background: Male patients with genital warts are known for higher rates of sexual dysfunction. This study was conducted to investigate whether human papillomaviruses (HPV) infection is associated with an increased risk of erectile dysfunction (ED).

Methods: Patients aged over 18 with HPV infection ( = 13,296) and propensity score-matched controls ( = 53,184) were recruited from the Longitudinal Health Insurance Database (LHID). Read More

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HPV Vaccination: Does It Have a Role in Preventing Penile Cancer and Other Preneoplastic Lesions?

Semin Oncol Nurs 2022 06 14;38(3):151284. Epub 2022 May 14.

Department of Urology, University Hospitals Leuven, Leuven, Belgium. Electronic address:

Objectives: Human papillomavirus (HPV) is the most common sexually transmitted infection globally, which causes nearly all cervix carcinomas and contributes to oropharyngeal, penile, vulva, vagina, and anal cancers. Despite the role of HPV in several preneoplastic and cancerous lesions in men, male vaccine coverage is low. This article aims to provide insights into the pathophysiology of HPV-related penile cancer and penile intraepithelial neoplasia (PeIN). Read More

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Corrigendum to "Epidemiological impact of the human papillomavirus vaccination program on genital warts in Portugal: A retrospective, chart review study" [Vaccine 40(2) (2022) 275-281].

Vaccine 2022 Jun 12;40(26):3720. Epub 2022 May 12.

Consulta de Doenças Sexualmente Transmissíveis, Centro de Saúde da Lapa, R. de São Ciro 36, 1200-830 Lisboa, Portugal.

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The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.

Int J Mol Sci 2022 Apr 20;23(9). Epub 2022 Apr 20.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Necker Hospital for Sick Children, 75015 Paris, France.

Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor (BLT), is a rare disease of the anogenital region. BLT is considered a locally aggressive tumor of benign histological appearance, but with the potential for destructive growth and high recurrence rates. BLT development is strongly associated with infection with low-risk human papillomaviruses (HPVs), mostly HPV-6 and -11. Read More

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Hospital resource utilisation from HPV-related diseases in England: a real-world cost analysis.

Eur J Health Econ 2022 May 13. Epub 2022 May 13.

Institute for Leadership and Management in Health, Kingston University, London, UK.

Background And Objective: HPV (human papillomavirus) is the virus most often responsible for sexually transmitted infections. The burden of HPV-related diseases on hospital resources represents a major public health problem. The objective of this study was to quantify the lifetime economic burden of HPV-related diseases based on hospital resources from the perspective of National Health Service (NHS) in England. Read More

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Development and psychometric properties of the human papillomavirus-quality of life (HPV-QoL) questionnaire to assess the impact of HPV on women health-related-quality-of-life.

Arch Gynecol Obstet 2022 May 13. Epub 2022 May 13.

EACCOS Research Group, Universidad Autónoma de Madrid, Madrid, Spain.

Purpose: The HPV-Quality-of-Life (HPV-QoL) questionnaire was developed to determine the impact of Human-Papillomavirus (HPV) infection and related interventions on women health-related quality-of-life. This study provides the development and preliminary psychometric properties of a novel HPV-QoL questionnaire for adult women with HPV.

Methods: After reviewing literature and cognitive debriefing interviews in women who had experienced HPV-related conditions, instrument items and domains were developed. Read More

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Case of penile white sponge nevus repeatedly treated as genital wart.

Sex Transm Infect 2022 May 6. Epub 2022 May 6.

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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[Approaches to increase HPV vaccination rate in Germany - challenges and opportunities. A qualitative study].

Z Evid Fortbild Qual Gesundhwes 2022 May 28;170:29-37. Epub 2022 Apr 28.

Stabsstelle Krebsprävention, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Deutschland. Electronic address:

Background: In Germany, the prevalence of infections with the human papilloma virus (HPV) among women and men is high. High-risk HPV types can lead to certain types of cancer (e. g. Read More

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Sexual function and sexual quality of life in men with genital warts: a cross-sectional study.

Reprod Health 2022 Apr 27;19(1):102. Epub 2022 Apr 27.

Department of Midwifery, School of Nursing and Midwifery, Community Based Psychiatric Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Human papillomavirus is the most common sexually transmitted infection, usually passing from one person to another after the first sexual activity. Infection with this virus and the occurrence of genital warts (GWs) could have several effects on patients' health. This study was performed to evaluate the sexual function and sexual quality of life (SQOL) in men with GWs. Read More

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Buske-Lowenstein Tumor: A Rare Cause of Genital Warts.

Cureus 2022 Mar 25;14(3):e23477. Epub 2022 Mar 25.

Emergency Medicine, Envision Physician Services, Plantation, USA.

The Buschke-Löwenstein tumor (BLT), also known as giant condylomata acuminata (GCA), is a pseudo-epithelial proliferation engendered by the human papillomavirus (HPV). Interestingly, its location at the anal margin, or perianal skin, is rare. The authors present the case of a gentleman who became unstable while standing, stating that his ears were ringing. Read More

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Incidence of anogenital warts after the introduction of the quadrivalent HPV vaccine program in Manitoba, Canada.

PLoS One 2022 26;17(4):e0267646. Epub 2022 Apr 26.

Vaccine and Drug Evaluation Centre, Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Background: The incidence of anogenital warts (AGW) decreased after the introduction of the quadrivalent human papillomavirus (qHPV) vaccine in multiple jurisdictions. We studied how comparing AGW incidence rates with different outcomes affects the interpretation of the qHPV vaccination program. To do this, we replicated multiple study designs within a single jurisdiction (Manitoba). Read More

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Effects of the Prophylactic HPV Vaccines on HPV Type Prevalence and Cervical Pathology.

Ian N Hampson

Viruses 2022 04 5;14(4). Epub 2022 Apr 5.

Division of Cancer Sciences, University of Manchester, Oxford Rd, Manchester M13 9WL, UK.

Vaccination programs with the current prophylactic HPV vaccines started in most countries around 2008 with introduction of the bivalent Cervarix HPV16/18 vaccine, rapidly followed by Gardasil (HPV6/11/16/18) and, finally, Gardasil 9 (HPV6/11/16/18/31/33/45/52/58), from 2015. Many studies have now confirmed their ability to prevent infection with vaccine-covered HPV types, and the subsequent development of either genital warts and/or cervical neoplasia, although this is clearly more effective in younger women vaccinated prior to sexual debut. Most notably, reductions in the prevalence of vaccine-covered HPV types were also observed in unvaccinated women at the same geographical location, presumably by sexual dissemination of these changes, between vaccinated and unvaccinated women. Read More

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Trends in HPV and HPV Vaccine Awareness among Gay and Bisexual Males in the U.S.

Vaccines (Basel) 2022 Apr 13;10(4). Epub 2022 Apr 13.

Division of Infectious Diseases, St. Mary's General Hospital, Passaic, NJ 07055, USA.

Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States (US). It is often discussed within the context of women's sexual health due to its association with cervical cancer. However, HPV is also associated with other cancers and conditions which affect men. Read More

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The prevalence and genotype distribution of human papillomavirus among women in Guangxi, southern China.

Infect Agent Cancer 2022 Apr 21;17(1):19. Epub 2022 Apr 21.

Department of Clinical Laboratory, Minzu Hospital of Guangxi Zhuang Autonomous Region, Affiliated Minzu Hospital of Guangxi Medical University, Nanning, 530001, Guangxi Zhuang Autonomous Region, China.

Background: Human papillomavirus is a primary cause of cervical cancer and genital warts. HPV vaccine can prevent high-grade cervical lesions as well as cervical cancer. The aim of this study was to analyze the prevalence and genotype distribution of human papillomavirus among women in Guangxi before and after the HPV vaccine was approved for use in China. Read More

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Anal human papillomavirus infection in kidney transplant recipients compared with immunocompetent controls.

Clin Infect Dis 2022 Apr 19. Epub 2022 Apr 19.

Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.

Background: Kidney transplant recipients (KTRs) have increased risk of human papillomavirus (HPV)-related anogenital (pre-)cancers, including anal high-grade intraepithelial lesions (HSIL) and cancer. Previous studies on anal high-risk HPV among KTRs are sparse.

Methods: In a cross-sectional study, we included 247 KTRs and 248 controls from a dermatology department and five nephrology departments in Denmark during 2016-2017. Read More

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Condyloma acuminata in under-represented groups: an All of Us database analysis.

Sex Transm Infect 2022 Apr 15. Epub 2022 Apr 15.

Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.

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Vaccines against sexually transmitted infections: an update.

Clin Exp Dermatol 2022 Apr 15. Epub 2022 Apr 15.

Department of Dermatology, Venereology, and Leprosy, KPC Medical College & Hospital, Kolkata, India.

Sexually transmitted infections (STI) constitute a major share of the diseases encountered by physicians. Although science has made considerable progress in terms of diagnosing and treating such infections, development of effective and safe vaccines is still needed. Syphilis, viral warts, gonorrhoea, genital herpes, chlamydia and trichomoniasis are the most common infections that are transmitted sexually. Read More

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Helping Children to Participate in Human Papillomavirus-Related Discussions: Mixed Methods Study of Multimedia Messages.

JMIR Form Res 2022 Apr 11;6(4):e28676. Epub 2022 Apr 11.

Department of Communication, University of Illinois at Urbana, Urbana, IL, United States.

Background: Human papillomavirus (HPV) can cause several types of cancers and genital warts. A vaccine is available to prevent HPV infections, and several efforts have been made to increase HPV education and, eventually, vaccination. Although previous studies have focused on the development of messages to educate children about HPV and the existence of the HPV vaccine, limited research is available on how to help children better communicate with their parents and health care professionals about the HPV vaccination. Read More

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The heterogeneity of Human Papilloma Virus genotypes in the oropharyngeal cavity, anus, and urogenital sites.

New Microbiol 2022 Jan 11;45(1):73-81. Epub 2021 Dec 11.

Translational Medicine, Vanguard and Technology Transfer Sector, Human Health Department, Central ADN Laboratories. Morelia, Michoacán, México, 58341.

The distribution of Human Papilloma Virus (HPV) genotypes is not homogeneous among the infectedcells in a specific anatomical site. Thus, we conducted a prospective cross-sectional studywith 2,130 Mexican men and women aged 16 to 80 years. We described the prevalence of HPVgenotypes at the oropharyngeal cavity, anus, and urogenital sites. Read More

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January 2022