591,899 results match your criteria Genital Herpes in Pregnancy


Aggressive Angiomyxoma: A Rare Tumor of Male Pelvic Cavity.

Acta Med Port 2018 Nov 30;31(11):693-696. Epub 2018 Nov 30.

Department of General Surgery. Ankara University School of Medicine. Ankara. Turkey.

Aggressive angiomyxoma is an uncommon, benign, slow-growing, and locally infiltrative soft tissue neoplasm which is located primarily in the genital region and pelviperineal interstitial tissue of female patient in the fourth decade of life. Its occurrence in male patients is even more unusual and commonly appears at a later age. The mainstay of treatment typically involves surgical excision with tumor-free margins, and despite complete resection, local recurrences are common. Read More

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November 2018
1 Read

Mutilating genital aphthous ulceration causing perforation in two women.

Clin Exp Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Dermatology, University of Medical Sciences, Haydarpaşa Numune Training and Research Hospital, Istanbul, 34662, Turkey.

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December 2018

The incidence and predictors of gynecologic malignancies among postmenopausal patients with endometrial fluid collection.

Authors:
Zhe Li Lei Li

Arch Gynecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Shuaifuyuan No 1, Dongcheng District, Beijing, China.

Objective: To investigate the incidence and predictors of gynecologic malignancies among postmenopausal patients with endometrial fluid collection (EFC).

Methods: All patients with EFC diagnosed by transvaginal sonography (TVS) were retrospectively reviewed if they had undergone biopsy of the endometrium from January 2008 to January 2016 in a tertiary teaching hospital. Follow-up ended in June 2017. Read More

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December 2018
1.279 Impact Factor

Young key affected population in Myanmar: are there any challenges in seeking information and care for HIV/sexually transmitted infections and reproductive health?

F1000Res 2018 21;7:1515. Epub 2018 Sep 21.

Department of Medical Research, Ministry of Health and Sports, Yangon, 11191, Myanmar.

Unmet needs and barriers in seeking HIV/STI and RH information and care are present especially among young key affected population (YKAP). Therefore, the study was conducted to determine the health seeking behaviors of YKAP regarding HIV/STI and RH, and challenges in seeking health information and care. A cross-sectional, mixed-methods study was conducted at two large cities in Myanmar. Read More

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September 2018

Human papillomavirus 16 E2 regulates keratinocyte gene expression relevant to cancer and the viral life cycle.

J Virol 2018 Dec 5. Epub 2018 Dec 5.

VCU Philips Institute for Oral Health Research, Virginia Commonwealth University School of Dentistry, Department of Oral and Craniofacial Molecular Biology, Richmond, VA 23298, USA.

Human papillomaviruses (HPV) are causative agents in ano-genital and oropharyngeal cancers. The virus must reprogram host gene expression to promote infection, and E6 and E7 contribute to this via targeting of cellular transcription factors including p53 and pRb, respectively. The HPV16 E2 protein regulates host gene expression in U2OS cells and in this study we extend these observations into TERT immortalized oral keratinocytes (NOKs) that are capable of supporting late stages of the HPV16 life cycle. Read More

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December 2018

Histidine-rich glycoprotein inhibits HIV-1 infection in a pH-dependent manner.

J Virol 2018 Dec 5. Epub 2018 Dec 5.

Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), Universidad de Buenos Aires (UBA) and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Histidine-rich glycoprotein (HRG) is an abundant plasma protein with a multidomain structure allowing its interaction with many ligands including phospholipids, plasminogen, fibrinogen, IgG antibodies, and heparan sulfate. HRG has shown to regulate different biological responses such as angiogenesis, coagulation and fibrinolysis. Here, we found that HRG almost completely abrogated the infection of GHOST, Jurkat, CD4+ T cells, and macrophages by HIV-1 at low pH (range 6. Read More

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December 2018

Alpha shapes: determining 3D shape complexity across morphologically diverse structures.

BMC Evol Biol 2018 Dec 5;18(1):184. Epub 2018 Dec 5.

School of Science and the Environment, Manchester Metropolitan University, Manchester, M1 5GD, UK.

Background: Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To use this data to address evolutionary and ecological questions, an array of tools has been developed to conduct shape analysis and quantify topographic complexity. Here we focus particularly on shape techniques applied to irregular-shaped objects lacking clear homologous landmarks, and propose a new 'alpha-shapes' method for quantifying 3D shape complexity. Read More

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December 2018

Human papillomaviruses' proteins with clinical utility.

J Immunoassay Immunochem 2018 Dec 5:1-10. Epub 2018 Dec 5.

a Department of Molecular Virology , Stefan S Nicolau Institute of Virology , Bucharest , Romania.

Cervical cancer, the fourth leading cause of cancer-associated deaths among women worldwide, is associated with human papilloma virus (HPV) infection. Despite the prophylactic HPV vaccination and the implementation of cervical and HPV-based screening programs, a significant increase in cervical cancer incidence is estimated by the year 2020. Thus, further development of diagnostic tools that allow detection and risk assesment in genital HPV infection is necessary. Read More

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December 2018

Lifetime Spousal Violence Victimization and Perpetration, Physical Illness, and Health Risk Behaviours among Women in India.

Int J Environ Res Public Health 2018 Dec 4;15(12). Epub 2018 Dec 4.

Department of Research & Innovation, University of Limpopo, Turfloop 0727, South Africa.

The aim of this study was to assess the association between lifetime spousal violence victimization, spousal violence perpetration, and physical health outcomes and behaviours among women in India. In the 2015⁻2016 National Family Health Survey, a sample of ever-married women (15⁻49 years) ( = 66,013) were interviewed about spousal violence. Results indicate that 29. Read More

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December 2018

The Role of Tumor Necrosis Factor α in the Biology of Uterine Fibroids and the Related Symptoms.

Int J Mol Sci 2018 Dec 4;19(12). Epub 2018 Dec 4.

First Department of Obstetrics and Gynecology, The Center of Postgraduate Medical Education, 01-004 Warsaw, Poland.

Uterine fibroids (UFs) are the most common benign tumors of the female genital tract. The incidence of UFs has been estimated at 25⁻80% depending on selected population. The pathophysiology of UFs remains poorly understood. Read More

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December 2018
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Type of pelvic disease as a risk factor for surgical site infection in women undergoing hysterectomy.

J Minim Invasive Gynecol 2018 Nov 30. Epub 2018 Nov 30.

The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa ON, K1Y 4E9.

Study Objective: To quantify the relationship between type of benign pelvic disease and risk of surgical site infection (SSI) after hysterectomy DESIGN: Retrospective Cohort (Classification II-2) SETTING: Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) PATIENT(S): Women who underwent hysterectomy from 2006-2015 and recorded in NSQIP database INTERVENTION: None MEASUREMENTS AND MAIN RESULTS: SSI risk was compared for type of benign pelvic diseases, patient characteristics (age, race and selected comorbidities) and process of care variables (admission status, type of hysterectomy, and operative time). Among a total of 125,337 women who underwent hysterectomy, 2.48% developed SSI. Read More

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November 2018

Germ cell neoplasia in situ complicating 17β-hydroxysteroid dehydrogenase type 3 deficiency.

Mol Cell Endocrinol 2018 Nov 30. Epub 2018 Nov 30.

Division of Metabolism, Endocrinology, & Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Pharmacology, University of Michigan, Ann Arbor, MI, USA.

17β-hydroxysteroid dehydrogenase type 3 (17βHSD3) deficiency is an autosomal recessive disorder of male sex development that results in defective testosterone biosynthesis. Although mutations in the cognate HSD17B3 gene cause a spectrum of phenotypic manifestations, the majority of affected patients are genetic males having female external genitalia. Many cases do not present until puberty, at which time peripheral conversion of androgen precursors causes progressive virilization. Read More

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November 2018

Ethical issues with early genitoplasty in children with disorders of sex development.

Curr Opin Endocrinol Diabetes Obes 2018 Nov 30. Epub 2018 Nov 30.

Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.

Purpose Of Review: Genitoplasty in children with disorders of sex development (DSD) is an ethically complex issue. From a surgical perspective, genitoplasty in early childhood is preferred because it is felt to be associated with improved tissue healing, decreased risk of complications, and reduced psychological impact of genital surgery. However, advocacy groups and recent ethics literature have argued for deferring genitoplasty until a child reaches decisional maturity. Read More

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November 2018

Lymphoganuloma venereum in the Western world, 15 years after its re-emergence: new perspectives and research priorities.

Curr Opin Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Department of Infectious Diseases, STI Outpatient Clinic, Public Health Service of Amsterdam.

Purpose Of Review: Lymphogranuloma venereum (LGV) is a serious sexually transmitted infection caused by Chlamydia trachomatis. If left untreated LGV can cause irreversible late sequelae. LGV is endemic among a high-risk population of men who have sex with men (MSM), and largely reported in Western metropoles. Read More

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November 2018
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Tenofovir 1% vaginal gel for prevention of HIV-1 infection in women in South Africa (FACTS-001): a phase 3, randomised, double-blind, placebo-controlled trial.

Lancet Infect Dis 2018 Nov 24;18(11):1241-1250. Epub 2018 Oct 24.

Wits RHI, University of the Witwatersrand, Johannesburg, South Africa.

Background: Young women in southern Africa have substantial risk of HIV acquisition. Female-controlled biomedical interventions are needed to mitigate this risk. We aimed to assess the safety and efficacy of a pericoitally applied tenofovir 1% gel. Read More

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November 2018

Review of the subgenus Plumiger of , with description of a new species (Heteroptera, Miridae, Halticini).

Zookeys 2018 15(796):215-239. Epub 2018 Nov 15.

National Museum of Natural History, Bulgarian Academy of Sciences, 1 Tsar Osvoboditel Blvd., 1000 Sofia, Bulgaria National Museum of Natural History, Bulgarian Academy of Sciences Sofia Bulgaria.

The Caucasian subgenus Plumiger Horváth, 1927 of the halticine genus Fieber, 1870 is revised. A key, updated diagnoses, and data on distribution are given for the subgenus and its four species, including (Georgia and Dagestan), and the previously unknown male of Drapolyuk, 1989. Illustrations of the male and female genitalia, photographs of the dorsal habitus, and SEM micrographs of selected structures are provided for all species of the subgenus. Read More

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November 2018

Disease Pattern among Sexually Transmitted Infection Clinic Attendees: A Hospital-Based Study.

Indian J Dermatol 2018 Nov-Dec;63(6):502-505

Department of Pediatrics, Base Hospital, New Delhi, India.

Background: Sexually transmitted infections (STIs) have a definite role in the facilitation of HIV infection, which, in turn, also increases susceptibility to other STIs. Further, the social stigma and secrecy surrounding STIs create difficulty in estimating its true incidence and prevalence.

Objective: The objective of this study was to know the pattern of diseases including different clinical presentations and final diagnosis among the STI clinic attendees. Read More

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December 2018

Herpes Simplex Virus 1 and 2 in Herpes Genitalis: A Polymerase Chain Reaction-Based Study from Kerala.

Indian J Dermatol 2018 Nov-Dec;63(6):475-478

National Institute of Virology, Kerala Unit, Palakkad, Kerala, India.

Background: Herpes genitalis is an ulcerating sexually transmitted infection, the clinical importance of which lies in its ability to produce painful and recurrent disease in addition to its potential role as a cofactor in acquisition and transmission of human immunodeficiency virus. In recent years, there are increasing reports of genital herpes due to herpes simplex virus (HSV)-1 from various parts of the world. Molecular diagnostic methods such as polymerase chain reaction (PCR) have got both diagnostic and prognostic significance in genital herpes. Read More

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December 2018

A Rare Mosaic Karyotype of 45,X/46,X,psu idic(Y)(p11.32)/46,XY with SHOX Haploinsufficiency, External Male Genitalia, and Short Stature.

Sex Dev 2018 Dec 1. Epub 2018 Dec 1.

In this case study, we describe a 3-year-old boy who was referred to the Inonu University Hospital with short stature complaint. His height was 86 cm (-2.96 SDS), weight was 12 kg (-2. Read More

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December 2018

Focus on neuro-Behçet's disease: A review.

Neurol India 2018 Nov-Dec;66(6):1619-1628

Department of Internal Medicine and Neurology, Neurological Clinic, Trieste, Italy.

Behçet's disease (BD) is a multisystemic vasculitis disorder of almost unknown etiology, which involves small and large vessels and affects both veins and arteries. BD is characterized by recurrent oral aphthae (the main and most recurrent symptoms), genital ulcers, variable skin lesions, arthritis, uveitis, and thrombophlebitis. Other reported symptoms concern the involvement of the gastrointestinal and the central nervous system. Read More

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December 2018

A high throughput bead-based affinity assay enables analysis of genital protein signatures in women at risk of HIV infection.

Mol Cell Proteomics 2018 Nov 30. Epub 2018 Nov 30.

Karolinska Institutet, Sweden.

Women at high risk of HIV infection, including sex workers and those with active genital inflammation, have molecular signatures of immune activation and epithelial barrier remodeling in samples of their genital mucosa. These alterations in the local immunological milieu are likely to impact HIV susceptibility. We here analyze host genital protein signatures in HIV uninfected women, with high frequency of condom use, living in HIV-serodiscordant relationships. Read More

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November 2018
2 Reads

Uterine histopathological changes induced by acute administration of tamoxifen and its modulation by sex steroid hormones.

Toxicol Appl Pharmacol 2018 Nov 29;363:88-97. Epub 2018 Nov 29.

UCIBIO, REQUIMTE, Departamento de Ciências Biológicas, Laboratório de Bioquímica, Faculdade de Farmácia, University of Porto, Porto, Portugal.

The endometrium is a particular sensitive target tissue for estradiol that is able to promptly modify its structure. Tamoxifen (TAM), a selective estrogen receptor modulator, was shown to promote a spectrum of uterine abnormalities, though the morphological and stereological effects of this drug in uterus is not clear. In this way, we have used an established model of ovariectomy followed by estradiol benzoate (EB) or TAM treatment and analyzed their effects in uterine histopathology and proliferation. Read More

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November 2018

[How I do… easily a vaginal sacrospinous colpopexy using an isthmic posterior mesh].

Gynecol Obstet Fertil Senol 2018 Nov 29. Epub 2018 Nov 29.

Département de gynécologie, hospices civils de Lyon, hôpital Femme-Mère-Enfant, HFME, 59, boulevard Pinel, 69000 Lyon, France.

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November 2018
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Greetings in male Guinea baboons and the function of rituals in complex social groups.

J Hum Evol 2018 Dec 3;125:87-98. Epub 2018 Nov 3.

Cognitive Ethology Laboratory, German Primate Center, Göttingen, Germany; Leibniz ScienceCampus Primate Cognition, Göttingen, Germany; Department for Primate Cognition, Georg-August-University Göttingen, Göttingen, Germany.

Ritualized greetings, defined as exchanges of non-aggressive signals, are common among males living in multi-male groups and are thought to balance the trade-offs of male co-residence. While ritualized greetings are widespread in the animal kingdom, the behavioral repertoire described in the genus Papio is exceptional, as it involves potentially harmful behaviors such as genital fondling. Although greetings are one of the most striking male social interactions in baboons, their function is still disputed. Read More

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December 2018

A mating plug in a squid? Sneaker spermatophores can block the female sperm-storage organ in Doryteuthis plei.

Zoology (Jena) 2018 Oct 8;130:47-56. Epub 2018 Sep 8.

Department of Zoology, Institute of Biosciences, University of São Paulo, Rua do Matão, Travessa 14, n. 101, 05508-090, São Paulo, SP, Brazil. Electronic address:

Males from numerous animal taxa have evolved strategies for obstructing the female genitalia with copulatory plugs, reducing the risk of sperm competition and thus resulting in an advantage in sexual selection. Several lines of evidence suggest that sperm competition is a common feature in the complex squid mating systems, which include the evolution of alternative mating tactics (consort vs. sneaker). Read More

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October 2018

Genital Tract Pathology in Female Pet Guinea Pigs (Cavia porcellus): a Retrospective Study of 655 Post-mortem and 64 Biopsy Cases.

J Comp Pathol 2018 Nov 19;165:13-22. Epub 2018 Oct 19.

Institute of Veterinary Pathology, Freie Universität Berlin, Robert-von-Ostertagstrase 15, Germany. Electronic address:

Disorders of the female genital tract are among the most common disorders in pet guinea pigs (Cavia porcellus); however, knowledge of many aspects of these disorders is sparse, especially regarding their incidence and age distribution. Ovarian cysts, as the most common genital tract disorder in guinea pigs, have been investigated in detail; however, information on the nature of these cysts is inconsistent. The present study reviewed genital tract disorders occurring within 655 full post-mortem examinations of intact female pet guinea pigs and 64 female genital tract biopsies examined over a 22. Read More

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November 2018

Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae and herpes simplex virus in Beijing, China.

Epidemiol Infect 2018 Dec 3:1-5. Epub 2018 Dec 3.

Department of Infection Control,Affiliated Hospital of Academy of Military Medical Sciences,Beijing,China.

The prevalence of sexually transmitted infection (STI) pathogens in Beijing, China, is rarely reported. In this study, 34 911 symptomatic outpatients with suspected genital infections who attended outpatient clinics in a tertiary care hospital were included to investigate the updated prevalence of Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and herpes simplex virus (HSV) from 1 January 2013 to 31 December 2016 in Beijing, China. Results indicated that a decrease trend (UU, CT, NG and HSV) in male and an increase trend (UU, CT and NG) in female were observed during the period. Read More

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December 2018

Association of phthalates, parabens and phenols found in personal care products with pubertal timing in girls and boys.

Hum Reprod 2018 Dec 4. Epub 2018 Dec 4.

Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, 1995 University Avenue, Berkeley, CA, USA.

Study Question: Are in-utero or peripubertal exposures to phthalates, parabens and other phenols found in personal care products associated with timing of pubertal onset in boys and girls?

Summary Answer: We found some associations of altered pubertal timing in girls, but little evidence in boys.

What Is Known Already: Certain chemicals in personal care and consumer products, including low molecular weight phthalates, parabens and phenols, or their precursors, are associated with altered pubertal timing in animal studies.

Study Design, Size, Duration: Data were from the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) longitudinal cohort study which followed 338 children in the Salinas Valley, California, from before birth to adolescence. Read More

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December 2018
2 Reads

Traumatic insemination is not the case in three Orius species (Heteroptera: Anthocoridae).

PLoS One 2018 5;13(12):e0206225. Epub 2018 Dec 5.

Division of Insect Sciences, The National Agriculture and Food Research Organization (NARO), Tsukuba, Japan.

Traumatic insemination (TI) is an extraordinary style of mating behavior wherein the female integument is pierced by the male extragenital structure to transfer the spermatozoa into the female's body through wounding. Flower bugs of the genus Orius belong to the family Anthocoridae (Heteroptera), which is referred to as the "TI family". Males possess sharp shaped extragenitalia, and females receive the extragenitalia using the copulatory tubes, which are specialized extragenital structures in Orius species. Read More

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December 2018

Treponema pallidum subsp. pallidum DNA and RNA in semen of a syphilis patient without genital or anal lesions. Possible implications for disease transmissibility.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle (WA) USA.

Treponema pallidum subsp. pallidum DNA and RNA were detected in a semen specimen of a syphilis patient with no genital or anal sores and no clinically evident orchitis. No nucleic acids were found in a urine sample of the same patient collected immediately before the semen sample. Read More

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December 2018
1 Read

Primary Angiosarcoma of the Cervix: Case Report of a Rare Lesion.

Int J Gynecol Pathol 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology, Royal Gwent Hospital, Newport (V.I.S., I.W.T.) Department of Pathology, University Hospital of Wales, Cardiff (G.L.R.) Department of Musculoskeletal Pathology, Royal Orthopaedic Hospital, Birmingham (V.P.S.) Department of Pathology, Belfast Health and Social Care Trust, Belfast (W.G.M.), UK.

Angiosarcomas of the female genital tract are rare and primary angiosarcoma of the cervix is extremely rare with only one prior case report. We report a case of a primary cervical angiosarcoma in a 43-yr-old woman who presented with heavy vaginal bleeding. Cervical biopsy and subsequent radical hysterectomy showed a malignant vascular tumor which was composed of spindled and epithelioid cells and formed abortive vascular channels. Read More

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December 2018
3 Reads

Plasticity Through Canalization: The Contrasting Effect of Temperature on Trait Size and Growth in .

Front Cell Dev Biol 2018 20;6:156. Epub 2018 Nov 20.

Department of Biology, Lake Forest College, Lake Forest, IL, United States.

In most ectotherms, a reduction in developmental temperature leads to an increase in body size, a phenomenon known as the temperature size rule (TSR). In , temperature affects body size primarily by affecting critical size, the point in development when larvae initiate the hormonal cascade that stops growth and starts metamorphosis. However, while the thermal plasticity of critical size can explain the effect of temperature on overall body size, it cannot entirely account for the effect of temperature on the size of individual traits, which vary in their thermal sensitivity. Read More

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November 2018
1 Read

Que faire en cas de clitoris augmenté de volume chez une petite fille ? À ne jamais négliger !

Rev Prat 2017 Apr;67(4):392-394

Endocrinologie et gynécologie, hôpital Bicêtre, faculté de médecine Paris-Sud, Le Kremlin-Bicêtre, France Centre de référence des maladies rares du développement génital.

What should be done in clitoral hypertrophy ? Clitoral hypertrophy is an infrequent variation/disorder of the sex development which requires a careful assessment. It should never be disregarded because it can reveal a congenital pathology that will have immediate vital consequences and result in low self-esteem, sexuality and fertility. This justifies an early multidisciplinary care and careful psychological support. Read More

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Comment réaliser un examen gynécologique chez la petite fille ? Établir un climat de confiance avec l’enfant et ses parents.

Rev Prat 2017 Apr;67(4):382-385

Service de pédiatrie, endocrinologie, génétique et gynécologie médicale, hôpital des Enfants, CHU de Toulouse, Toulouse France.

How to perform a gynecological examination in the girl ? Precautionary gynecological examination is very important in the pre-pubescent girl, since it allows the diagnosis of most pathologies. Parents should be present in order to establish a climate of trust. The most suitable position is that of "the frog". Read More

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Maladie de Verneuil.

Authors:
Denis Soudan

Rev Prat 2017 Sep;67(7):757-766

Service de colo-proctologie, institut de proctologie Léopold-Bellan, hôpital Saint-Joseph, Paris, France.

Hidradenitis Suppurativa. Verneuil disease or hidradenitis suppurativa (HS) chronic, inflammatory, recurrent debilitating disease develops after puberty, with cutaneous and sub-cutaneous painfull nodules in the apocrine sweat glands regions (axillary inguinal and ano genital regions). Prevalence is 1% in Europe. Read More

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September 2017

Troubles pelvi-périnéaux du post-partum. Fréquents et à rechercher systématiquement à l’interrogatoire.

Rev Prat 2016 Feb;66(2):207-210

Université Paris-Sud, UMR-S0782, Clamart, France.

Postpartum pelvic floor disorders. Postpartum pelvic floor disorders are frequent but most of the time, decrease spontaneously. Even if 40% of pregnant women suffer from urinary incontinence, 85% of them are cured 3 months after delivery. Read More

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February 2016

Anogenital Verrucous Carcinoma-A case report.

Int J Surg Case Rep 2018 Nov 27;54:7-9. Epub 2018 Nov 27.

Department of Plastic Surgery and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.

Introduction: Verrucous carcinoma is an uncommon variant of low-grade squamous cell malignancy with a low malignant potential but a high risk of recurrence.

Presentation Of Case: We report a case of a Human Papilloma Virus negative local verrucous carcinoma in the perianal area of a 45-year old otherwise healthy female. The tumor presented clinically as a persistent genital wart not responding to usual dermatologic local therapy. Read More

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November 2018
2 Reads

Case Report: Persistent Genital Arousal Disorder in an Adolescent Woman.

Authors:
Kelly A Curran

J Pediatr Adolesc Gynecol 2018 Dec 1. Epub 2018 Dec 1.

Section of Adolescent Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, 1200 Children's Avenue, Suite 12204 Oklahoma City, OK. Electronic address:

Background: After several visits with unrelated complaints, a 16-year-old female disclosed symptoms of unwanted genital arousal and was diagnosed with persistent genital arousal disorder (PGAD).

Case: A 16-year-old female with history of depression, sexual abuse, and dysmenorrhea insistently requested etonogestrel rod removal. At two visits following implant removal, the patient disclosed the reason for her insistence: PGAD symptoms developed after implant insertion, though they worsened with removal. Read More

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December 2018
10 Reads

Live-attenuated varicella zoster virus vaccine does not induce HIV target cell activation.

J Clin Invest 2018 Dec 4. Epub 2018 Dec 4.

Background: Varicella-zoster virus (VZV) is under consideration as a promising recombinant viral vector to deliver foreign antigens including HIV. However, new vectors have come under increased scrutiny since vaccination with Ad5-vectored HIV vaccine trials demonstrated increased HIV risk in individuals with pre-immunity to the vector which was thought to be associated with mucosal immune activation (IA). Therefore, defining the impact of VZV vaccination on IA is particularly important with the prospect of developing an HIV/VZV chimeric vaccine. Read More

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December 2018

Non-therapeutic male genital cutting and harm: Law, policy and evidence from U.K. hospitals.

Bioethics 2018 Dec 4. Epub 2018 Dec 4.

Law, University of Leeds, Leeds, Yorkshire, United Kingdom of Great Britain and Northern Ireland.

Female genital cutting (FGC) is generally understood as a gendered harm, abusive cultural practice and human rights violation. By contrast, male genital cutting (MGC) is held to be minimally invasive, an expression of religious identity and a legitimate parental choice. Yet scholars increasingly problematize this dichotomy, arguing that male and female genital cutting can occasion comparable levels of harm. Read More

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December 2018
4 Reads

Application of ultrasound in aggressive angiomyxoma: Eight case reports and review of literature.

World J Clin Cases 2018 Nov;6(14):811-819

Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, China.

Aggressive angiomyxoma (AAM) is a rare tumour that often occurs in soft tissues of the female genital tract. Eight cases of AAM are reported in this article, and the clinical features and ultrasound and magnetic resonance imaging (MRI) results of the eight cases are reviewed and summarized. The main complaints of all the patients were palpable and painless masses in the vulva or scrotum. Read More

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November 2018
1 Read

Ulcer of Lipschutz, a rare and unknown cause of genital ulceration.

Facts Views Vis Obgyn 2018 Mar;10(1):55-57

Hospital Notre Dame des Bruyères, CHU, Obstetrics and Gynecology, Rue de Gaillarmont 600, 4032 Chênée, Belgium.

Acute genital ulcers are painful and distressing to women. Lipchutz Ulcer is an uncommon disease that typically occurs in sexually inactive young women. The main differential diagnosis are sexually-transmitted or non-infectious diseases which cause genital or oro-genital ulcerations. Read More

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March 2018
5 Reads

Concurrent presence of buccal mucosal and ophthalmologic lesions in Behcet's syndrome.

Caspian J Intern Med 2018 ;9(4):325-327

Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Behcet's syndrome is a disease with different aspects in its clinical manifestations. The purpose of this study was to evaluate the simultaneous presence of oral mucosal and ophthalmologic lesions in patients with Behcet's syndrome.

Methods: From April 2012 to December 2014, 50 cases of Behcet's syndrome who referred to the Departments of Ophtalmology, Oral Diseases and Infectious Diseases of Babol University Medical Sciences were entered into the study. Read More

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January 2018

Transverse testicular ectopia associated with persistent Müllerian duct syndrome treated by transseptal orchiopexy: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13305

Departments of Urology.

Rationale: Persistent Müllerian duct syndrome (PMDS) is rare form of male pseudohermaphroditism characterized by the presence of uterus and fallopian tubes with normal external genitalia and secondary sexual characteristics. Transverse testicular ectopia (TTE) is also a rare form of testicular ectopia that may be associated with PMDS.

Patient Concerns: We present a 2-year-old boy who presented with bilateral non-palpable testes with left inguinal mass. Read More

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November 2018
1 Read

Perspectives on female genital cutting among immigrant women and men in Boston.

Soc Sci Med 2018 Nov 22;220:331-339. Epub 2018 Nov 22.

Brigham and Women's Hospital, Boston, MA, USA. Electronic address:

This study documents the perceptions and experiences of immigrant women and men in the US related to female genital cutting (FGC). This paper examines the effects of migration on these perceptions, with the goal of optimizing health services and informing public policy to support women who have undergone FGC. This qualitative study consisted of individual interviews conducted from 2014 to 2015 with 42 women and men living in Boston, Massachusetts, who immigrated from a variety of communities where FGC has been practiced. Read More

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November 2018

Azithromycin-based Extended-Spectrum Antibiotic Prophylaxis for Cesarean: Role of Placental Colonization with Genital Ureaplasmas and Mycoplasmas.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  To explore whether the effect of azithromycin (AZI) on postcesarean infections varied by the presence/absence of genital mycoplasmataceae placental colonization.

Materials And Methods:  This was a single-center substudy of multicenter double-blind C/SOAP (Cesarean Section Optimal Antibiotic Prophylaxis) trial of women randomized to AZI or placebo (+cefazolin) antibiotic prophylaxis at cesarean. Chorioamnion/placenta specimens were tested for genital mycoplasmataceae colonization by polymerase chain reaction. Read More

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November 2018
3 Reads

Trends of Anogenital Warts Among Sexually Transmitted Disease Clinic Patients - Sexually Transmitted Disease Surveillance Network, United States, 2010-2016.

J Infect Dis 2018 Nov 29. Epub 2018 Nov 29.

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB; Centers for Disease Control and Prevention; Atlanta, GA, USA.

Background: Approximately 90% of genital warts are caused by human papillomavirus (HPV) types 6 and 11. In the US, HPV vaccination has been recommended for females ≤26 years; and since 2011, males ≤21 years and gay, bisexual, and other men who have sex with men (MSM) ≤26 years.

Methods: Data were obtained from 27 clinics participating in the STD Surveillance Network (SSuN). Read More

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November 2018
4 Reads

Letter to the Editor: "Characterization of the CYP11A1 Non-synonymous Variant p.E314K in Children Presenting with Adrenal Insufficiency".

J Clin Endocrinol Metab 2018 Nov 30. Epub 2018 Nov 30.

Laboratoire de Biochimie et Biologie Moléculaire Grand Est, UM Pathologies Endocriniennes Rénales Musculaires et Mucoviscidose, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France.

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November 2018
3 Reads

Diabetes Mellitus and lower genital tract tears after vaginal birth: A cohort study.

Midwifery 2018 Nov 22;69:121-127. Epub 2018 Nov 22.

Department of Obstetrics and Gynaecology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200, Denmark; Department of Clinical Medicine, Aarhus University, Incuba / Skejby Building 2 Palle Juul-Jensens Boulevard 82, Aarhus DK-8200, Denmark. Electronic address:

Introduction: Diabetes Mellitus in pregnancy is increasing. No existing studies have examined Diabetes Mellitus as the primary exposure for lower genital tract tears after vaginal birth. The objective was to study the association between Diabetes Mellitus (all types combined), Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus and Gestational Diabetes Mellitus and lower genital tract tears after vaginal birth. Read More

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November 2018

Biological properties and production of bacteriocins-like-inhibitory substances by Lactobacillus spp. strains from human vagina.

J Appl Microbiol 2018 Nov 30. Epub 2018 Nov 30.

Università degli Studi di Catania, Dipartimento di Scienze Biomediche e Biotecnologiche BIOMETEC Sez. Microbiologia, Torre Biologica, via S. Sofia 97, 95123, Catania, Italy.

Aims: The aim of this study was to characterize Lactobacillus strains for their biological properties and amensalistic activities against genital and non-genital pathogens.

Methods And Results: For the purpose, some special characteristics (H O , biofilm and antimicrobial substances production) as well as safety properties of 112 lactobacilli were evaluated. All the strains had good amensalistic characteristics, in particular cell-free supernatants (CFS) of ten strains showed antibacterial activity against bacteria, as well as Candida spp. Read More

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November 2018
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