7,874 results match your criteria Generalized Anxiety Disorder


Cognitive-behavioral therapy (CBT) for generalized anxiety disorder: Contrasting various CBT approaches in a randomized clinical trial.

J Clin Psychol 2019 Apr 20. Epub 2019 Apr 20.

Department of Clinical Psychology and Psychotherapy/International Institute for the Advanced Study of Psychotherapy and Applied Mental Health, Babeş-Bolyai University, No 37 Republicii Street, Cluj-Napoca, Romania.

Objective: Cognitive-behavior therapy (CBT) is considered the "golden standard" psychotherapy for generalized anxiety disorder (GAD) but, at this point, we have little information about differences among various CBT approaches.

Method: We conducted a randomized controlled trial to compare three CBT protocols for GAD: (a) Cognitive Therapy/Borkovec's treatment package; (b) Rational Emotive Behavior Therapy, and (c) Acceptance and Commitment Therapy/Acceptance-based behavioral therapy. A number of 75 patients diagnosed with GAD, aged between 20 and 51 (m = 27. Read More

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http://dx.doi.org/10.1002/jclp.22779DOI Listing

Brazilian Jiu Jitsu Training for US Service Members and Veterans with Symptoms of PTSD.

Mil Med 2019 Apr 20. Epub 2019 Apr 20.

Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd, Tampa, FL 33612.

Introduction: The United States has been actively involved in major armed conflicts over the last 15 years. As a result, a significant proportion of active duty service personnel and returning veterans have endured combat, putting them at risk for developing post-traumatic stress disorder (PTSD), a disabling disorder that may occur after exposure to a traumatic event. Current therapies often require long-term, time-intensive and costly commitment from the patient and have variable degrees of success. Read More

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https://academic.oup.com/milmed/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/milmed/usz074DOI Listing
April 2019
1 Read

The role of long-term psychodynamic psychotherapy in improving attachment patterns, defense styles, and alexithymia in patients with depressive/anxiety disorders.

Trends Psychiatry Psychother 2019 Jan-Mar;41(1):43-50. Epub 2019 Apr 11.

Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran.

Introduction: Long-term psychodynamic psychotherapy (LTPP) emphasizes the centrality of intrapsychic and unconscious conflicts and their relation to development. Although there is evidence supporting the efficacy of LTPP in mental disorders, little research has been published on the efficacy of LTPP for depressive and anxiety disorders.

Objective: To examine whether patients with anxiety and depressive disorders demonstrate improvement in their attachment styles, defense styles, psychiatric symptoms, anxiety/depressive symptoms, and alexithymia with LTPP. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/2237-6089-2017-0144DOI Listing
April 2019
2 Reads

Emotion sensitivity and self-reported symptoms of generalized anxiety disorder across the lifespan: A population-based sample approach.

Brain Behav 2019 Apr 16:e01282. Epub 2019 Apr 16.

Institute for Technology in Psychiatry, McLean Hospital, Belmont, Massachusetts.

Background: Individuals with generalized anxiety disorder (GAD) symptoms show deficits in emotion processing, but results of prior studies have been conflicting, and little is known about developmental trajectories of emotion processing over time. We examined the association between GAD symptoms and sensitivity to recognizing emotional facial expressions (emotion sensitivity: ES) for three emotions (happiness, anger, fear) in a large, diverse, population-based sample. We hypothesized that higher anxiety scores would be associated with poorer performance, and expected that ES performance and anxiety scores would decline across the lifespan. Read More

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http://dx.doi.org/10.1002/brb3.1282DOI Listing

Mental Health Status, Need, and Unmet Need for Mental Health Services Among U.S. Pacific Islanders.

Psychiatr Serv 2019 Apr 17:appips201800455. Epub 2019 Apr 17.

Center for Healthy Communities, School of Medicine, University of California, Riverside (Subica); College of Health, University of Utah, Salt Lake City (Aitaoto); School of Public Policy, University of California, Riverside (Link); Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles (Yamada, Henwood); Borrego Health, Borrego Springs, California (Sullivan).

Objective: This study examined the mental health status, need for services, and unmet need of community-dwelling Native Hawaiian and other Pacific Islanders (NHPI).

Methods: Survey data were collected from 223 NHPI adults of Samoan or Marshallese heritage. Surveys were translated into Samoan and Marshallese by using back-translation, with feedback from cultural experts. Read More

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https://psychiatryonline.org/doi/10.1176/appi.ps.201800455
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http://dx.doi.org/10.1176/appi.ps.201800455DOI Listing
April 2019
2 Reads

Measuring treatment outcome in patients with anxiety disorders: A comparison of the responsiveness of generic and disorder-specific instruments.

J Anxiety Disord 2019 Apr 6;64:55-63. Epub 2019 Apr 6.

Institute of Psychology, Faculty of Social Sciences, Leiden University, Pieter De La Court Building, P.O. Box 9555, 2300 RB Leiden, the Netherlands; Stichting Benchmark GGZ, Rembrandtlaan 46, 3723 BK Bilthoven, the Netherlands. Electronic address:

Background: For routine outcome monitoring, generic (i.e., broad-based) and disorder-specific instruments are used to monitor patient progress. Read More

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http://dx.doi.org/10.1016/j.janxdis.2019.04.001DOI Listing
April 2019
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Novel Risk Factors for Posttraumatic Stress Disorder Symptoms in Family Members of Acute Respiratory Distress Syndrome Survivors.

Crit Care Med 2019 Apr 15. Epub 2019 Apr 15.

Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, WA.

Objectives: Family members of ICU survivors report long-term psychologic symptoms of posttraumatic stress disorder. We describe patient- and family-member risk factors for posttraumatic stress disorder symptoms among family members of survivors of acute respiratory distress syndrome.

Design: Prospective cohort study of family members of acute respiratory distress syndrome survivors. Read More

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http://dx.doi.org/10.1097/CCM.0000000000003774DOI Listing
April 2019
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Online help-seeking prior to diagnosis: Can web-based resources reduce the duration of untreated mood disorders in young people?

J Affect Disord 2019 Apr 8;252:130-134. Epub 2019 Apr 8.

Department of Psychiatry Research, The Zucker Hillside Hospital, 75-59 263rd Street, Glen Oaks, 11004 NY, USA; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA; The Feinstein Institute for Medical Research, Manhasset, NY, USA.

Objective: Mood and anxiety disorders typically begin in adolescence or early adulthood, but those at the age of highest risk are among those least likely to access mental health services. However, they may be more likely than other demographic groups to seek help online. The goal of the present study was to investigate the online help- and information-seeking activity of young people newly diagnosed with mood and anxiety disorders in order to better understand how digital resources might serve this population. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.019DOI Listing
April 2019
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Factorial invariance of a computerized version of the GAD-7 across various demographic groups and over time in primary care patients.

J Affect Disord 2019 Apr 9;252:114-121. Epub 2019 Apr 9.

Department of Psychology, Maimónides Institute for Research in Biomedicine of Cordoba-IMIBIC, Reina Sofía University Hospital, University of Córdoba, Av. Menéndez Pidal, s/n, 14004 Córdoba, Spain. Electronic address:

Background: The Generalized Anxiety Disorder 7-item scale (GAD-7) is commonly used by clinicians and researchers to screen for anxiety disorders and to monitor anxiety symptoms in primary care. However, findings regarding its factor structure are mixed, with most studies reporting a best-fitting for a one-factor structure, whereas others indicate a two-factor model. To be valid for comparisons, the GAD-7 should measure the same latent construct with the same structure across groups and over time. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.032DOI Listing

Oral and Dental Findings in Emanuel Syndrome.

Int J Paediatr Dent 2019 Apr 13. Epub 2019 Apr 13.

Postgraduate Program Director, Division of Pediatric Dentistry, Department of Craniofacial Sciences, School of Dental Medicine, University of Connecticut Health Center, Farmington, CT.

Emanuel Syndrome (ES; OMIM# 609029) is a rare disorder caused by an unbalanced chromosomal translocation [supernumerary der(22)t(11,22)] and characterized by multiple congenital abnormalities. With limited published cases and low prevalence (1:110,000), detailed ES-associated oro-dentals findings have not previously been reported. This is a case-report of a 14-year-old male with ES who presented with congenital cardiac, renal, auditory, musculo-skeletal problems, and global developmental delay. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ipd.12502
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http://dx.doi.org/10.1111/ipd.12502DOI Listing
April 2019
2 Reads

Six-Month Prevalence of Mental Disorders and Service Contacts among Children and Youth in Ontario: Evidence from the 2014 Ontario Child Health Study.

Can J Psychiatry 2019 Apr;64(4):246-255

5 In alphabetical order: Tracie O. Afifi (University of Manitoba), William R. Avison (Western University), Kathryn Bennett (McMaster University), Terry Bennett (McMaster University), Khrista Boylan (McMaster University), Michael H. Boyle (McMaster University), Michelle Butt (McMaster University), John Cairney (University of Toronto), Corine Carlisle (University of Toronto), Kristin Cleverley (Centre for Addiction and Mental Health, University of Toronto), Ian Colman (University of Ottawa), Jinette Comeau (King's University College at Western University), Charles Cunningham (McMaster University), Scott Davies (University of Toronto), Claire de Oliveira (Centre for Addiction and Mental Health, University of Toronto), Melanie Dirks (McGill University), Eric Duku (McMaster University), Laura Duncan (McMaster University), Jim Dunn (McMaster University), Mark A. Ferro (University of Waterloo), Katholiki Georgiades (McMaster University), Stelios Georgiades (McMaster University), Andrea Gonzalez (McMaster University), Geoffrey Hall (McMaster University), Joanna Henderson (Centre for Addiction and Mental Health, University of Toronto), Magdalena Janus (McMaster University), Jennifer Jenkins (University of Toronto), Melissa Kimber (McMaster University), Ellen Lipman (McMaster University), Harriet MacMillan (McMaster University), Ian Manion (Royal's Institute of Mental Health Research), John McLennan (University of Ottawa), Amelie Petitclerc (Northwestern University), Anne Rhodes (University of Toronto), Graham Reid (Western University), Peter Rosenbaum (McMaster University), Roberto Sassi (McMaster University), Louis Schmidt (McMaster University), Cody Shepherd (Simon Fraser University), Noam Soreni (McMaster University), Peter Szatmari (Centre for Addiction and Mental Health, Hospital for Sick Children, University of Toronto), Brian Timmons (McMaster University), Juliana Tobon (McMaster University), Ryan Van Lieshout (McMaster University), Charlotte Waddell (Simon Fraser University), Li Wang (McMaster University), Christine Wekerle (McMaster University).

Objectives: To present the 6-month prevalence and sociodemographic correlates of mental disorders and mental health-related service contacts in a sample of children (4 to 11 years) and youth (12 to 17 years) in Ontario.

Methods: The 2014 Ontario Child Health Study is a provincially representative survey of 6537 families with children aged 4 to 17 years in Ontario. DSM-IV-TR mental disorders were assessed using the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) and included mood (major depressive episode), anxiety (generalized anxiety, separation anxiety, social phobia, specific phobia), and behaviour disorders (attention-deficit/hyperactivity disorder, oppositional-defiant disorder, conduct disorder). Read More

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http://dx.doi.org/10.1177/0706743719830024DOI Listing
April 2019
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Protocol for the Inroads Study: A Randomized Controlled Trial of an Internet-Delivered, Cognitive Behavioral Therapy-Based Early Intervention to Reduce Anxiety and Hazardous Alcohol Use Among Young People.

JMIR Res Protoc 2019 Apr 12;8(4):e12370. Epub 2019 Apr 12.

The Matilda Centre, University of Sydney, Sydney, Australia.

Background: The transition to adulthood is a unique developmental period characterized by numerous personal and social role changes and increased opportunities for alcohol consumption. Using alcohol to cope with anxiety symptoms is commonly reported, and young people with anxiety are at a greater risk of hazardous alcohol use and progression to alcohol use disorder. Anxiety and alcohol use tend to fuel each other in an exacerbating feed-forward cycle, leading to difficult-to-treat chronic problems. Read More

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http://dx.doi.org/10.2196/12370DOI Listing
April 2019
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Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion.

Mol Psychiatry 2019 Apr 11. Epub 2019 Apr 11.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, 30322, USA.

The 3q29 deletion confers increased risk for neuropsychiatric phenotypes including intellectual disability, autism spectrum disorder, generalized anxiety disorder, and a >40-fold increased risk for schizophrenia. To investigate consequences of the 3q29 deletion in an experimental system, we used CRISPR/Cas9 technology to introduce a heterozygous deletion into the syntenic interval on C57BL/6 mouse chromosome 16. mRNA abundance for 20 of the 21 genes in the interval was reduced by ~50%, while protein levels were reduced for only a subset of these, suggesting a compensatory mechanism. Read More

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http://dx.doi.org/10.1038/s41380-019-0413-5DOI Listing
April 2019
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External validation of the International Risk Prediction Algorithm for the onset of generalized anxiety and/or panic syndromes (The Predict A) in the US general population.

J Anxiety Disord 2019 Apr 3;64:40-44. Epub 2019 Apr 3.

Institute of Mental Health Research, University of Ottawa, Ottawa, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada. Electronic address:

Introduction: Multivariable risk prediction algorithms are useful for making clinical decisions and health planning. While prediction algorithms for new onset of anxiety disorders in Europe and elsewhere have been developed, the performance of these algorithms in the Americas is not known. The objective of this study was to validate the PredictA algorithm for new onset of anxiety and/or panic disorders in the US general population. Read More

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http://dx.doi.org/10.1016/j.janxdis.2019.03.004DOI Listing
April 2019
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Outcome prediction from post-injury resilience in patients with TBI.

Rehabil Psychol 2019 Apr 11. Epub 2019 Apr 11.

Department of Physical Medicine and Rehabilitation.

Purpose/objective: The objective of the study was to evaluate the extent to which 1- and 2-year outcomes after traumatic brain injury (TBI) are predicted by resilience. Research Method/Design: This was an observational, longitudinal study of persons ( = 158) with moderate or severe TBI who completed both 1- and 2-year outcome assessments. Outcomes included anxiety (Generalized Anxiety Disorder-7), depression (Patient Health Questionnaire-9), life satisfaction (Satisfaction with Life Scale), substance misuse, and return-to-work measures. Read More

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http://doi.apa.org/getdoi.cfm?doi=10.1037/rep0000263
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http://dx.doi.org/10.1037/rep0000263DOI Listing
April 2019
4 Reads

Modulation of fear generalization by the zona incerta.

Proc Natl Acad Sci U S A 2019 Apr 9. Epub 2019 Apr 9.

Neuroscience Graduate Program, Emory University, Atlanta, GA 30329;

Fear expressed toward threat-associated stimuli is an adaptive behavioral response. In contrast, the generalization of fear responses toward nonthreatening cues is a maladaptive and debilitating dimension of trauma- and anxiety-related disorders. Expressing fear to appropriate stimuli and suppressing fear generalization require integration of relevant sensory information and motor output. Read More

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http://dx.doi.org/10.1073/pnas.1820541116DOI Listing
April 2019
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Resting-state connectivity of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in clinical anxiety

J Psychiatry Neurosci 2019 Apr 9;44(3):1-11. Epub 2019 Apr 9.

From the Section on the Neurobiology of Fear and Anxiety, National Institute of Mental Health, Bethesda, MD, USA (Torrisi, Alvarez, Gorka, Fuchs, Geraci, Grillon, Ernst).

Background: The central nucleus of the amygdala and bed nucleus of the stria terminalis are involved primarily in phasic and sustained aversive states. Although both structures have been implicated in pathological anxiety, few studies with a clinical population have specifically focused on them, partly because of their small size. Previous work in our group used high-resolution imaging to map the restingstate functional connectivity of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in healthy subjects at 7 T, confirming and extending structural findings in humans and animals, while providing additional insight into cortical connectivity that is potentially unique to humans. Read More

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http://dx.doi.org/10.1503/jpn.180150DOI Listing
April 2019
4 Reads

Genetic counseling considerations with rapid genome-wide sequencing in a neonatal intensive care unit.

J Genet Couns 2019 Apr 31;28(2):263-272. Epub 2018 Dec 31.

Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.

As genome-wide sequencing (GWS; exome sequencing [ES] and whole genome sequencing [WGS]) is implemented more frequently in the neonatal intensive care unit (NICU), it is important to understand parents' opinions regarding GWS, and views toward incidental findings (IFs) (also known as secondary findings). RAPIDOMICS was a pilot study of rapid trio-based (biological parents and neonate) ES for 25 neonates with a suspected genetic condition at the BC Women's Hospital NICU. As part of RAPIDOMICS, we explored parents' motivations and concerns regarding ES of their child, uptake of IFs for themselves, and rates of anxiety and depression at the time of pre-test genetic counseling via administration of the Generalized Anxiety Disorder Assessment 7 and Patient Health Questionnaire 8. Read More

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http://dx.doi.org/10.1002/jgc4.1074DOI Listing
April 2019
2 Reads

Treatment of Gastrointestinal Symptoms and Mood Disorder With Physical Medicine and Supplementation: A Case Report.

Integr Med (Encinitas) 2018 Jun;17(3):53-58

all affiliated with the National University of Natural Medicine in Portland, Oregon.

This report details the naturopathic treatment of a 28-y-old female with a 1 y history of abdominal pain, heartburn, and constipation as well as longstanding anxiety and depression. Clinical evaluation ruled out organic causes of dyspepsia such as peptic ulcer disease, infection, and nonsteroidal anti-inflammatory drugs-induced dyspepsia. Treatment consisting of soft-tissue manipulation, homeopathic prescription, nutritional supplementation, and lifestyle modification greatly improved gastrointestinal and mental-emotional symptoms after 2 wk. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396765PMC
June 2018
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Prevalence and associated factors of depression and anxiety among doctoral students: the mediating effect of mentoring relationships on the association between research self-efficacy and depression/anxiety.

Psychol Res Behav Manag 2019 21;12:195-208. Epub 2019 Mar 21.

Department of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China,

Purpose: Although the mental health status of doctoral students deserves attention, few scholars have paid attention to factors related to their mental health problems. We aimed to investigate the prevalence of depression and anxiety in doctoral students and examine possible associated factors. We further aimed to assess whether mentoring relationships mediate the association between research self-efficacy and depression/anxiety. Read More

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http://dx.doi.org/10.2147/PRBM.S195131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432885PMC
March 2019
1 Read

Coping with stress: A pilot study of a self-help stress management intervention for patients with epileptic or psychogenic nonepileptic seizures.

Epilepsy Behav 2019 Apr 5;94:169-177. Epub 2019 Apr 5.

Academic Neurology Unit, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.

Purpose: Many patients with epilepsy or psychogenic nonepileptic seizures (PNES) experience high levels of stress. Although psychological interventions have been developed for seizure disorders, few patients can currently access them. We aimed to assess the acceptability and feasibility of a self-help intervention targeting stress in patients with seizures, and to provide preliminary evidence for its effectiveness. Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.03.002DOI Listing
April 2019
2 Reads

Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease: A Randomized Clinical Trial.

JAMA Neurol 2019 Apr 8. Epub 2019 Apr 8.

The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region.

Importance: Clinical practice guidelines support exercise for patients with Parkinson disease (PD), but to our knowledge, no randomized clinical trials have tested whether yoga is superior to conventional physical exercises for stress and symptom management.

Objective: To compare the effects of a mindfulness yoga program vs stretching and resistance training exercise (SRTE) on psychological distress, physical health, spiritual well-being, and health-related quality of life (HRQOL) in patients with mild-to-moderate PD.

Design, Setting, And Participants: An assessor-masked, randomized clinical trial using the intention-to-treat principle was conducted at 4 community rehabilitation centers in Hong Kong between December 1, 2016, and May 31, 2017. Read More

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http://dx.doi.org/10.1001/jamaneurol.2019.0534DOI Listing
April 2019
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An exploratory structural equation modeling bi-factor analytic approach to uncovering what burnout, depression, and anxiety scales measure.

Psychol Assess 2019 Apr 8. Epub 2019 Apr 8.

Institute of Work and Organizational Psychology, The University of Neuchâtel.

In this study, we addressed the ongoing debate about what burnout and depression scales measure by conducting an exploratory structural equation modeling (ESEM) bifactor analysis. A sample of 734 U.S. Read More

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http://dx.doi.org/10.1037/pas0000721DOI Listing
April 2019
2 Reads

Do patients with ICD who report anxiety symptoms on Hospital Anxiety and Depression Scale suffer from anxiety?

J Psychosom Res 2019 Mar 29. Epub 2019 Mar 29.

Department of Cardiology, Herlev and Gentofte University Hospital, Niels Andersens Vej 65, 2900 Hellerup, Denmark.

Objectives: The objectives were to determine: 1) whether patients with an implantable cardioverter defibrillator (ICD) presenting with anxiety symptoms measured on the Hospital Anxiety and Depression Scale (HADS) have identifiable anxiety according to the Structured Clinical Interview for DSM disorders (SCID) and 2) the type of anxiety, if any, behind a HADS-A score ≥ 8 in patients with an ICD.

Methods: Patients with an ICD were screened using HADS and patients with a HADS-A score ≥ 8 were invited to participate. A total of 88 patients were included in the study and were interviewed using the SCID instrument to determine anxiety or adjustment disorder. Read More

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http://dx.doi.org/10.1016/j.jpsychores.2019.03.183DOI Listing
March 2019
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Age-specific associations among functional COMT ValMet polymorphism, resting parasympathetic nervous control and generalized anxiety disorder.

Psychoneuroendocrinology 2019 Mar 30;106:57-64. Epub 2019 Mar 30.

Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address:

The functional ValMet polymorphism (rs4680) of the Catechol-O-Methyltransferase (COMT) gene has been implicated in generalized anxiety disorder (GAD); however, the underlying neural mechanisms remain unexamined. Recent evidence reveals that low resting parasympathetic (vagal) control is an endophenotypic predictor of anxiety, while the effect of COMT rs4680 differs at different ages. Thus, we examined whether the COMT ValMet variant could increase the risk of GAD through decreased resting parasympathetic nervous control in an age-specific manner. Read More

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http://dx.doi.org/10.1016/j.psyneuen.2019.03.020DOI Listing
March 2019
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Disrupted interhemispheric resting-state functional connectivity and structural connectivity in first-episode, treatment-naïve generalized anxiety disorder.

J Affect Disord 2019 Mar 30;251:280-286. Epub 2019 Mar 30.

Department of Radilogy, Changzheng Hospital, The Navy Military Medical University, No.415 Fengyang Road, Huangpu District, Shanghai 200003, China. Electronic address:

Background: Aberrant functional and structural connectivity are considered to be involved in the underlying neural mechanism of generalized anxiety disorder (GAD). However, alterations in functional and structural interactions between the bilateral hemispheres are rarely examined. The current study aimed to characterized interhemispheric resting-state functional connectivity and white matter microstructural integrity of the corpus callosum in patients with GAD. Read More

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http://dx.doi.org/10.1016/j.jad.2019.03.082DOI Listing
March 2019
2 Reads
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The Correlation Between Dry Eyes, Anxiety and Depression: The Sicca, Anxiety and Depression Study.

Cornea 2019 Apr 2. Epub 2019 Apr 2.

Department of Ophthalmology, University of North Carolina, Chapel Hill, NC.

Purpose: To determine whether improvement in the severity of dry eye disease (DED) symptoms correlates with improvement in anxiety and depression.

Methods: This prospective interventional case series recruited 45 adults with evidence of DED. Patients were administered the University of North Carolina Dry Eye Management Scale (DEMS), Generalized Anxiety Disorder 7-item scale (GAD-7), and Personal Health Questionnaire Depression Scale (PHQ-8) to evaluate the severity of DED symptoms, anxiety, and depression, respectively. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001932DOI Listing
April 2019
2 Reads

The Prevalence of Psychiatric Disorders Among Elective Plastic Surgery Patients.

Eplasty 2019 18;19:e6. Epub 2019 Mar 18.

University of Kansas School of Medicine, Kansas City, KS.

Psychiatric disorder is one of the predictors of poor outcome in cosmetic plastic surgery patients. A US study in 1960 showed that 72.4% of 98 cosmetic plastic surgery patients had a psychiatric disorder. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432998PMC
March 2019
1 Read

Relationship between major depressive disorder, generalized anxiety disorder and coronary artery disease in the US general population.

J Psychosom Res 2019 Apr 18;119:8-13. Epub 2019 Jan 18.

University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Psychiatry, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

Objective: To evaluate whether the changes and persistence of major depressive disorder (MDD) and generalized anxiety disorder (GAD) affect the risk of incident coronary artery disease (CAD) in the US general population.

Methods: Data was retrieved from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) conducted in 2001/2002 (Wave 1) and 2004/2005 (Wave 2). At both Wave 1 and one year before Wave 2, MDD and GAD were measured using the Alcohol Use Disorders and Associated Disabilities Interview Schedule IV. Read More

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http://dx.doi.org/10.1016/j.jpsychores.2019.01.007DOI Listing
April 2019
1 Read

Somatization, Depression, and Anxiety Disorders in a Rhinology Practice.

Am J Rhinol Allergy 2019 Apr 5:1945892419841317. Epub 2019 Apr 5.

1 Department of Otolaryngology, Head and Neck Surgery, Miller School of Medicine, University of Miami, Miami, Florida.

Background: Patients present to rhinology clinics with various complaints. Symptoms may be attributable to objective findings, some remain unexplained. The objective is to investigate the incidence of psychological disorders in a rhinologic practice and evaluate a correlation of these psychiatric diseases with rhinologic symptoms. Read More

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http://dx.doi.org/10.1177/1945892419841317DOI Listing
April 2019
3 Reads

Psychiatric Considerations in the Management of Dizzy Patients.

Authors:
Jeffrey P Staab

Adv Otorhinolaryngol 2019 15;82:170-179. Epub 2019 Jan 15.

Research over the last 4 decades has revealed a great deal of information about psychiatric and functional causes, consequences, and comorbidity of vestibular syndromes. Primary care clinicians, neurologists, and otologists who are willing to set aside the 20th century notion of "psychogenic dizziness" and incorporate 21st century concepts about 5 behavioral entities into their practices will be rewarded for their efforts with a marked improvement in diagnostic acumen and therapeutic effectiveness. Panic attacks may cause or contribute to acute or episodic vestibular symptoms. Read More

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https://www.karger.com/Article/FullText/490286
Publisher Site
http://dx.doi.org/10.1159/000490286DOI Listing
January 2019
3 Reads

A Problem-Solving Intervention for Hospice Family Caregivers: A Randomized Clinical Trial.

J Am Geriatr Soc 2019 Apr 4. Epub 2019 Apr 4.

School of Nursing, University of Washington, Seattle, Washington.

Objectives: Family caregivers of hospice patients have multiple needs as they try to cope during a stressful time. Translatable interventions effective in improving caregiver outcomes are greatly needed. Our objective was to assess the impact of a problem-solving intervention (called Problem-Solving Intervention to Support Caregivers in End-of-Life Care Settings [PISCES]) to support hospice caregivers on caregiver quality of life and anxiety, and compare its effectiveness delivered face to face and via videoconferencing. Read More

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http://dx.doi.org/10.1111/jgs.15894DOI Listing
April 2019
7 Reads

Inquiry into the correlation between burnout and depression.

J Occup Health Psychol 2019 Apr 4. Epub 2019 Apr 4.

Institute of Work and Organizational Psychology.

The extent to which burnout refers to anything other than a depressive condition remains an object of controversy among occupational health specialists. In three studies conducted in two different countries and two different languages, we investigated the discriminant validity of burnout scales by evaluating the magnitude of the correlation between (latent) burnout and (latent) depression. In Study 1 ( = 911), burnout was assessed with the Maslach Burnout Inventory-General Survey's Exhaustion subscale and depression with the depression module of the Patient Health Questionnaire (PHQ). Read More

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http://dx.doi.org/10.1037/ocp0000151DOI Listing
April 2019
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Description of the Treatment Course by Pregabalin for Anxiety in Patients With a Major Neurocognitive Disorder.

J Clin Psychopharmacol 2019 May/Jun;39(3):261-263

Background: Anxiety symptoms frequently experienced by patients with a major neurocognitive disorder (NCD) are often treated with long-term benzodiazepines despite known adverse effects. Pregabalin has shown efficacy in generalized anxiety disorders but has not been studied in patients with a major NCD. The objective of this study was to describe the use of pregabalin for anxiety in patient with a major NCD and the impact of its use on the pharmacological treatment change. Read More

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http://dx.doi.org/10.1097/JCP.0000000000001029DOI Listing
April 2019
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The Psychometric Properties and Clinical Utility of the Korean Version of GAD-7 and GAD-2.

Front Psychiatry 2019 18;10:127. Epub 2019 Mar 18.

Department of Psychology, Korea University Mind Health Institute, Korea University, Seoul, South Korea.

Generalized anxiety disorder (GAD) is a common but serious form of anxiety disorder. Despite this, the rate of GAD recognition in primary care remains low in both Western and Eastern countries. The GAD-7 and GAD-2 were developed to efficiently identify people with GAD, and their reliability and validity have been well-documented in Western countries. Read More

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http://dx.doi.org/10.3389/fpsyt.2019.00127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431620PMC
March 2019
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Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.

JAMA Neurol 2019 Apr 1. Epub 2019 Apr 1.

UCB Pharma, Raleigh, North Carolina.

Importance: Limited population-based data are available on antiepileptic drug (AED) treatment patterns in women of childbearing age with epilepsy; the current population risk is not clear.

Objectives: To examine the AED treatment patterns and identify differences in use of valproate sodium and topiramate by comorbidities among women of childbearing age with epilepsy.

Design, Setting, And Participants: A retrospective cohort study used a nationwide commercial database and supplemental Medicare as well as Medicaid insurance claims data to identify 46 767 women with epilepsy aged 15 to 44 years. Read More

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http://dx.doi.org/10.1001/jamaneurol.2019.0447DOI Listing
April 2019
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Identification of Factors Affecting the Quality of Life Among Patients With Addiction in Lebanon.

J Nerv Ment Dis 2019 May;207(5):378-383

Faculty of Sciences, Lebanese University, Beirut, Lebanon.

Our objective was to assess factors associated with the physical (Short-Form 12-physical component summary [SF-12-PCS]) and mental (Short-Form 12-mental component summary [SF-12-MCS]) quality of life (QOL) in the Lebanese population. A cross-sectional study, conducted between July and September 2017, enrolled 57 patients with substance use disorder from the Psychiatric Hospital of the Cross. The SF-12 scale was used to assess the QOL among participants. Read More

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http://dx.doi.org/10.1097/NMD.0000000000000982DOI Listing
May 2019
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The Course of Adverse Events in Venlafaxine XR Treatment in Generalized Anxiety Disorder.

J Clin Psychopharmacol 2019 May/Jun;39(3):258-260

Department of General Studies, Harcum College, Media, PA.

Purpose: The time course of adverse events is an important factor for patient management. Clinicians are better able to prepare patients for specific adverse events, which leads to better treatment adherence.

Methods: Adverse events were followed longitudinally for 6 months during the open-label phase of a relapse prevention trial with 264 patients with generalized anxiety disorder. Read More

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http://dx.doi.org/10.1097/JCP.0000000000001027DOI Listing
April 2019
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Psychological Interventions for the Fear of Public Speaking: A Meta-Analysis.

Front Psychol 2019 15;10:488. Epub 2019 Mar 15.

Department of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.

Fear of Public Speaking (FoPS) or public speaking anxiety is a type of social anxiety and the single most commonly feared situation in the population. FoPS is disabling with negative occupational, academic, and social consequences, reported by up to one third of the population. FoPS in adolescence and adulthood is associated with an increased risk of developing generalized social anxiety disorder with further impairments. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428748PMC
March 2019
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The Revised Child Anxiety and Depression Scales (RCADS): Psychometric Evaluation in Children Evaluated for ADHD.

J Psychopathol Behav Assess 2019 Mar 17;41(1):93-106. Epub 2018 Oct 17.

Department of Psychology, Miami University, Oxford, Ohio, USA.

Co-occurring internalizing symptoms are common and important to assess in children with attention-deficit/hyperactivity disorder (ADHD). One frequently used child self-report measure of internalizing symptoms is the Revised Child Anxiety and Depression Scales (RCADS), yet the psychometric properties of the RCADS remain unexamined in children referred for ADHD specifically. The present study evaluated the RCADS in 117 children (ages 8-12; 66% male) evaluated for suspected ADHD at an ADHD specialty clinic (83% met criteria for ADHD). Read More

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http://link.springer.com/10.1007/s10862-018-9702-6
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http://dx.doi.org/10.1007/s10862-018-9702-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438181PMC
March 2019
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Repeated measures study of the association between musculoskeletal symptoms and mental health in subway workers.

Ind Health 2019 Mar 30. Epub 2019 Mar 30.

Department of Occupational and Environmental Medicine, Ajou University Hospital, Korea.

While the prevalence of musculoskeletal disorders has recently increased among Korean workers employed in highly physically and psychologically demanding jobs, the relation among these domains remains relatively unexplored. We examined 2,037 subway workers in Seoul, that collected data via questionnaire survey on musculoskeletal symptoms and the work environment, administered in 2009, 2012, and 2015. Generalized estimating equation (GEE) analysis was used for statistical analysis. Read More

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http://dx.doi.org/10.2486/indhealth.2018-0206DOI Listing
March 2019
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Case Report: Neuropsychiatric Symptoms in PKU Disease.

J Pediatr Health Care 2019 Mar 28. Epub 2019 Mar 28.

Phenylketonuria is a rare inborn error of metabolism. The build-up of phenylalanine in the blood and body tissues can have significant impact on the brain's development. High phenylalanine levels have been shown to be associated with an increase in neuropsychiatric symptoms, including mood, anxiety, and attention problems; decreased social competence; and low self-esteem. Read More

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http://dx.doi.org/10.1016/j.pedhc.2019.02.007DOI Listing
March 2019
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Psychiatric diagnosis in primary care patients with increased depressive symptoms.

Nord J Psychiatry 2019 Apr;73(3):195-199

a School of Medicine, General Practice , University of Eastern Finland , Kuopio , Finland.

Background: Screening of depression has been recommended in primary care and Beck's 21-item Depression Inventory (BDI-21) is a commonly used tool for screening. Depression has been shown to be frequently accompanied by comorbidities.

Aims: This study aimed to analyze the characteristics, psychiatric diagnoses, and psychiatric comorbidity of primary care patients who have been screened for depression and referred to a depression nurse. Read More

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http://dx.doi.org/10.1080/08039488.2019.1584240DOI Listing
April 2019
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Quality of Life of Caregivers of Older Patients with Advanced Cancer.

J Am Geriatr Soc 2019 Mar 29. Epub 2019 Mar 29.

URCC NCORP Research Base, University of Rochester Medical Center, Rochester, New York.

Objectives: To evaluate the relationships between aging-related domains captured by geriatric assessment (GA) for older patients with advanced cancer and caregivers' emotional health and quality of life (QOL).

Design: In this cross sectional study of baseline data from a nationwide investigation of older patients and their caregivers, patients completed a GA that included validated tests to evaluate eight domains of health (eg, function, cognition).

Setting: Thirty-one community oncology practices throughout the United States. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgs.15862
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http://dx.doi.org/10.1111/jgs.15862DOI Listing
March 2019
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Prevalence of Disagreement About Appropriateness of Treatment Between ICU Patients/Surrogates and Clinicians.

Chest 2019 Mar 26. Epub 2019 Mar 26.

Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.

Background: ICU patients/surrogates may experience adverse outcomes related to perceived inappropriate treatment. The objective was to determine the prevalence of patient/surrogate-reported perceived inappropriate treatment, its impact on adverse outcomes, and discordance with clinicians.

Methods: We conducted a multicenter, prospective, observational study of adult ICU patients. Read More

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http://dx.doi.org/10.1016/j.chest.2019.02.404DOI Listing
March 2019
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Allergies, asthma, and psychopathology in a nationally-representative US sample.

J Affect Disord 2019 Mar 6;251:130-135. Epub 2019 Mar 6.

Department of Epidemiology, School of Public Health, University of Michigan, United States; Institute for Social Research, University of Michigan, United States.

Background: Symptoms of depressed mood and anxiety have been associated with immune dysregulation and atopic disorders, however it is unclear whether this relationship spans other forms of psychopathology. The objective of this study was to use a large, population-based sample to examine the association between several common psychiatric conditions and two atopic disorders: seasonal allergies and asthma. This study also examined whether comorbidity between psychiatric disorders confounded the relationship between atopy and each psychiatric disorder. Read More

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http://dx.doi.org/10.1016/j.jad.2019.03.026DOI Listing
March 2019
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When is pharmacotherapy required for children suffering from Generalized Anxiety Disorder?

Expert Opin Pharmacother 2019 Mar 28:1-4. Epub 2019 Mar 28.

a Department of Psychiatry , University of Milan, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2019.1
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http://dx.doi.org/10.1080/14656566.2019.1595583DOI Listing
March 2019
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The Relationship Between Adverse Childhood Experiences and Health Care Use in the Manitoba IBD Cohort Study.

Inflamm Bowel Dis 2019 Mar 23. Epub 2019 Mar 23.

From the University of Manitoba IBD Clinical and Research Centre.

Background: We aimed to determine the prevalence of adverse childhood experiences (ACEs) in persons with inflammatory bowel disease (IBD) and whether having ACEs was associated with health care utilization post-IBD diagnosis.

Method: Three hundred forty-five participants from the population-based Manitoba IBD Cohort Study self-reported ACEs (ie, physical abuse, sexual abuse, death of a very close friend or family member, severe illness or injury, upheaval between parents, and any other experience thought to significantly impacts one's life or personality) at a median of 5.3 years following IBD diagnosis. Read More

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http://dx.doi.org/10.1093/ibd/izz054DOI Listing
March 2019
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