11,195 results match your criteria Generalized Anxiety Disorder


Infralow-frequency transcranial magnetic stimulation as a therapy for generalized anxiety disorder: A randomized clinical trial.

Compr Psychiatry 2022 Jun 11;117:152332. Epub 2022 Jun 11.

Department of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China. Electronic address:

Background: Generalized anxiety disorder (GAD) is a common chronic mental disorder, and it also can cause depressive symptoms and cognitive impairment. The primary aim of this study was to determine whether inflow-frequency transcranial magnetic stimulation (ILF-TMS) improves anxiety symptoms in patients with GAD.

Methods: Sixty-two patients with GAD were randomly divided into 2 groups. Read More

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Factors Related to Anxiety and Depression Among Adolescents During COVID-19: A Web-Based Cross-Sectional Survey.

J Korean Med Sci 2022 Jun 27;37(25):e199. Epub 2022 Jun 27.

Department of Psychology, Keimyung University, Daegu, Korea.

Background: The coronavirus disease 2019 (COVID-19) outbreak and subsequent disease-containment measures (such as school closures) significantly affected the lives of adolescents. We evaluated the mental-health status and factors associated with anxiety and depression among South Korean adolescents.

Methods: A nationwide online survey was conducted to evaluate the mental-health status of South Korean adolescents during the COVID-19 pandemic. Read More

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Transperineal Botulinum Toxin Injection for Chronic Pelvic Pain Syndrome after Transurethral Resection of the Prostate.

Urol J 2022 Jun 26. Epub 2022 Jun 26.

Department of Anesthesiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Purpose: To evaluate the efficacy of botulinum toxin type A (BTX-A) injection in patients with chronic pelvic pain syndrome (CPPS) after transurethral resection of the prostate (TURP).

Materials And Methods: Six patients after TURP received the injection of BTX-A around the prostate capsule or pelvic floor under ultrasound guidance. The clinical outcomes including overall pain intensity (assessed by visual analog scale, VAS), the Functional Pelvic Pain scale (FPPS), and mental state by anxiety and depression questionnaires, the generalized anxiety disorder (GAD-7) and Hamilton depression rating scale (HAM-D)) were assessed at pre-treatment, and 1, 4, 12 weeks after treatment. Read More

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Prevalence and determinants of anxiety in patients with epilepsy during COVID-19 pandemic.

Egypt J Neurol Psychiatr Neurosurg 2022 23;58(1):78. Epub 2022 Jun 23.

Psychiatry Department, Faculty of Medicine, Zagazig University, P.O. Box 44519, Zagazig, Egypt.

Background: Epilepsy is one of the most frequent and serious brain disorders. The nature of the disorder and the unpredictability of seizures usually puts patients in a state of apprehension and anticipation, which creates a continuous condition of anxiety. COVID-19 pandemic has created a state of generalized anxiety all over the world. Read More

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Generalized anxiety disorder among mothers attending perinatal services during COVID-19 pandemic: using ordinal logistic regression model.

Heliyon 2022 Jun 22;8(6):e09778. Epub 2022 Jun 22.

Department of Statistics, College of Natural and Computational Science, Mizan-Tepi University, P.O. Box 121, Tepi, Ethiopia.

Background: Generalized anxiety disorder is characterized by excessive and uncontrollable worry about a variety of events. It is critical to ensure a pregnant mother's mental health in order to reduce pregnancy and birth-related problems. The major goal of current study was to identify the factors associated with generalized anxiety disorder among mothers attending perinatal services in the study area during COVID-19 using ordinal logistic regression. Read More

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Robbery Victimization in Early Adulthood, and Depression and Anxiety at Age 30 Years: Results From the 1982 Pelotas (Brazil) Birth Cohort Study.

Front Public Health 2022 9;10:821881. Epub 2022 Jun 9.

Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

Robbery is one of the most common urban crimes, but little is known about its relationship with mental disorders in young adults. This study aimed to assess the relationship between robbery victimization and Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD) and comorbidity between MDD and GAD at 30 years of age. A birth cohort study has followed all children born in the city of Pelotas, southern Brazil, since 1982. Read More

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Application of Chain Nursing Process in the Nursing of Elderly Inpatients with Implantable Venous Infusion Port.

Emerg Med Int 2022 16;2022:5496533. Epub 2022 Jun 16.

Department of Urology Surgery, First People's Hospital of Linping District, Hangzhou 311100, Zhejiang, China.

Objective: To explore the application effects of chain nursing process in the nursing of elderly inpatients with implantable venous infusion port.

Methods: 81 elderly inpatients who were treated with implantable venous infusion port in the hospital were selected between February 2018 and December 2021, and they were divided into the routine group (given routine nursing of implantable venous infusion port,  = 40) and the study group (given chain nursing process intervention on the basis of the routine group,  = 41) according to the random number table method. The patients in both groups were intervened for 1 month. Read More

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Comparison of Lamotrigine and Oxcarbazepine Monotherapy Among Chinese Adult Patients With Newly-Diagnosed Focal-Onset Epilepsy: A Prospective Observational Study.

Front Neurol 2022 10;13:855498. Epub 2022 Jun 10.

Department of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Objective: We performed a prospective cohort study to compare the efficacy, safety, effect on mood, and quality of life between lamotrigine (LTG) and oxcarbazepine (OXC) monotherapy among Chinese adult patients with newly-diagnosed focal-onset epilepsy (FOE) with or without secondarily generalized tonic-clonic seizures.

Methods: We enrolled 106 adult patients with new-onset FOE, of whom 56 were in the OXC group and 50 in the LTG group. Their clinical characteristics were detailly recorded especially basic seizure frequency, seizure types, and drug-related adverse events. Read More

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Neurocircuitry of treatment in anxiety disorders.

Biomark Neuropsychiatry 2022 Jun 22;6. Epub 2022 Apr 22.

Department of Psychiatry & Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.

Background: Understanding how treatments change neurobiology is critical to developing predictors of treatment response. This is especially true for anxiety disorders-the most common psychiatric disorders across the lifespan. With this in mind, we examined neurofunctional predictors of treatment response and neurofunctional changes associated with treatment across anxiety disorders. Read More

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Screening Tool for Mental Health Problems During COVID-19 Pandemic: Psychometrics and Associations With Sex, Grieving, Contagion, and Seeking Psychological Care.

Front Psychol 2022 10;13:882573. Epub 2022 Jun 10.

Sección Mexicana de la Comisión de Salud Fronteriza México-Estados Unidos, Mexico City, Mexico.

Background: The COVID-19 pandemic has created a public mental health crisis. Brief, valid electronic tools are required to evaluate mental health status, identify specific risk factors, and offer treatment when needed.

Objective: To determine the construct validity, reliability, and measurement invariance of a brief screening tool for mental health symptoms by sex, loss of loved ones, personal COVID-19 status, and psychological care-seeking during the COVID-19 pandemic. Read More

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A prospective study of transdiagnostic psychiatric symptoms associated with burnout and functional difficulties in COVID-19 frontline healthcare workers.

J Psychiatr Res 2022 Jun 9;152:219-224. Epub 2022 Jun 9.

Yale School of Medicine, Yale University School of Medicine, United States.

Objective: Frontline healthcare workers (FHCWs) responding to the COVID-19 pandemic develop posttraumatic stress disorder (PTSD), major depressive disorder (MDD) and generalized anxiety disorder (GAD) symptoms. Such symptoms are associated with burnout, occupational and relational difficulties. In the current study, we examined the prospective association between acute transdiagnostic COVID-19-related PTSD, MDD, and GAD symptoms at pandemic outset, and burnout and functional difficulties several months later in FHCWs in New York City. Read More

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Not always that EASI: Validating the Russian version of the epilepsy anxiety survey instrument and its brief counterpart.

Epilepsy Behav 2022 Jun 23;133:108801. Epub 2022 Jun 23.

Moscow Research and Clinical Center for Neuropsychiatry, Donskaya ul., 43, Moscow, Russian Federation; Pirogov Russian National Research Medical University, Ostrovitianova ul., 1, Moscow, Russian Federation.

Objective: To develop a Russian version of The Epilepsy Anxiety Survey Instrument (EASI) and assess its psychometric properties in a Russian sample of patients with epilepsy (PWE). To compare the brief version of EASI with the General Anxiety Disorder-7 (GAD-7) - the most common tool for a rapid anxiety screening.

Methods: The study sample consisted of 181 consecutive Russian-speaking PWE. Read More

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Associated Psychological Factors of Viral Load among Self-Isolating Nigerian COVID-19 Patients.

West Afr J Med 2022 Jun;39(6):588-594

Department of Public Health, Osun State Ministry of Health, Osogbo, Osun State, Nigeria.

Background: Corona virus disease 2019 (COVID-19) is a pandemic that has affected millions of people worldwide. The aim of this study was to explore the psychological factors of viral load among COVID-19 patients who were on self-isolation in Nigeria.

Methods: This is a cross-sectional study involving five hundred and nine self-isolating COVID-19 patients in Osogbo, Nigeria. Read More

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Prevalence and Related Factors of Anxiety Among University Teachers 1 Year After the COVID-19 Pandemic Outbreak in China: A Multicenter Study.

Front Psychiatry 2022 2;13:823480. Epub 2022 Jun 2.

Emergency Medicine Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Objectives: This study aimed to evaluate the prevalence of anxiety among university teachers 1 year after the onset of the coronavirus disease 2019 (COVID-19) pandemic and provide empirical evidence of psychological intervention.

Methods: A multicenter study was conducted to examine the prevalence of anxiety among 10,302 teachers in 21 Chinese universities from February 12 to April 23, 2021. The generalized Anxiety Disorder 7-item Scale (GAD-7) was used to assess symptoms of anxiety. Read More

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The Associations of Suspected COVID-19 Symptoms with Anxiety and Depression as Modified by Hemodialysis Dietary Knowledge: A Multi-Dialysis Center Study.

Nutrients 2022 Jun 7;14(12). Epub 2022 Jun 7.

School of Nutrition and Health Sciences, Taipei Medical University, Taipei 110-31, Taiwan.

During the COVID-19 pandemic, it is essential to evaluate hemodialysis patients' dietary knowledge, especially among those with COVID-19 related symptoms, in order to identify appropriate strategies in managing their mental health. The study's purposes were to test the psychometric properties of the hemodialysis dietary knowledge (HDK) scale, and to investigate the modifying impact of HDK on the associations of suspected COVID-19 symptoms (S-COVID-19-S) with anxiety and depression among hemodialysis patients. A cross-sectional study was conducted from July 2020 to March 2021 at eight hospitals across Vietnam. Read More

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A Cross-Sectional Time Course of COVID-19 Related Worry, Perceived Stress, and General Anxiety in the Context of Post-Traumatic Stress Disorder-like Symptomatology.

Int J Environ Res Public Health 2022 Jun 11;19(12). Epub 2022 Jun 11.

Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21287, USA.

The COVID-19 pandemic within the United States of America resulted in over 800,000 deaths as of February 2022 and has been addressed by social distancing or stay-at-home measures. Collective prolonged multimodal trauma on this scale is likely to elicit symptomatology in the general population consistent with post-traumatic stress disorder (PTSD), somatization, anxiety, and stress. The psychological component of this response contributes substantially to the burden of this disease worldwide. Read More

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A Changing Home: A Cross-Sectional Study on Environmental Degradation, Resettlement and Psychological Distress in a Western German Coal-Mining Region.

Int J Environ Res Public Health 2022 Jun 10;19(12). Epub 2022 Jun 10.

Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52070 Aachen, Germany.

Unwelcome environmental changes can lead to psychological distress, known as "solastalgia". In Germany, the open-pit mining of brown coal results in environmental changes as well as in the resettlement of adjacent villages. In this study, we investigated the risk of open-pit mining for solastalgia and psychological disorders (e. Read More

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Investigating Strategies of Emotion Regulation As Mediators of Occupational Stressors and Mental Health Outcomes in First Responders.

Int J Environ Res Public Health 2022 Jun 8;19(12). Epub 2022 Jun 8.

Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT 06510, USA.

The aim of this study was to investigate whether two emotion regulation strategies, expressive suppression or cognitive reappraisal, mediated the development of posttraumatic stress disorder (PTSD), major depression (MD), and generalized anxiety disorder (GAD) in first responders (FR) who experienced occupational stressors, using cross-sectional data. An aggregate of 895 first responders (M = 37.32, SD = 12. Read More

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A Trying Time: Problematic Internet Use (PIU) and its association with depression and anxiety during the COVID-19 Pandemic.

Child Adolesc Psychiatry Ment Health 2022 Jun 23;16(1):49. Epub 2022 Jun 23.

Department of Pediatrics, Kentucky Children's Hospital, Suite L407, Lexington, KY, 40536, USA.

Background: The prevalence of problematic Internet use (PIU) among adolescents and young adults (AYA) was approximately 9-11% before the COVID-19 pandemic. The purpose of this study was to determine the prevalence of PIU among AYAs (especially younger adolescents) during the COVID-19 pandemic using the Problematic and Risky Internet Use Screening Scale (PRIUSS). Additionally, we examined the relationship between PIU, depression and anxiety among AYAs during the same period. Read More

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E-Learning Impact on Veterinary Medical Student's Mental Health during the COVID-19 Pandemic.

J Vet Med Educ 2022 Jun 23:e20210052. Epub 2022 Jun 23.

Veterinary medical students are known to have significant levels of mental illness. The COVID-19 pandemic and the shift to online learning have brought increased psychological stress. We used a web-based survey to ask 415 veterinary medical students from Portugal about the impact of the pandemic and online learning on their anxiety levels. Read More

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Screening for Distress and Health Outcomes in Head and Neck Cancer.

Curr Oncol 2022 May 24;29(6):3793-3806. Epub 2022 May 24.

Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.

Head and neck cancers (HNC) have higher rates of emotional distress than other cancer types and the general population. This paper compares the prevalence of emotional distress in HNC across various distress screening measures and examines whether significant distress or distress screening are associated with cancer-related survival. A retrospective observational cohort design was employed, with data collected from the Distress Assessment and Response Tool (DART) and linkages to administrative databases from 2010 to 2016. Read More

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Implementing genomics in the neonatal period: An assessment of parental decision making and anxiety.

J Genet Couns 2022 Jun 22. Epub 2022 Jun 22.

Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

As uptake of rapid genome sequencing (GS) in the neonatal period steadily increases, a clinical genetics service that is optimized to the needs of parents becomes increasingly important. We aimed to investigate factors that influence decision making about rapid GS by parents of infants admitted to neonatal intensive care units (NICU) and explore their experiences of decisional conflict and anxiety during this time. Parents of neonates suspected of having a genetic disorder and offered rapid GS in the NICU completed a questionnaire measuring experience with GS counseling, decisional conflict, and anxiety level. Read More

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Prevalence and associated risk factors for mental health problems among patients with polycystic ovary syndrome in Bangladesh: A nationwide cross-Sectional study.

PLoS One 2022 22;17(6):e0270102. Epub 2022 Jun 22.

Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh.

Background: Polycystic ovary syndrome (PCOS) is a common female reproductive endocrine problem worldwide. The prevalence of mental disorder is increasing among PCOS patients due to various physical, psychological, and social issues. Here we aimed to evaluate the mental health and associated factors among women suffering from PCOS in Bangladesh. Read More

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Only Human: Mental-Health Difficulties Among Clinical, Counseling, and School Psychology Faculty and Trainees.

Perspect Psychol Sci 2022 Jun 22:17456916211071079. Epub 2022 Jun 22.

Department of Psychology, University of South Florida.

How common are mental-health difficulties among applied psychologists? This question is paradoxically neglected, perhaps because disclosure and discussion of these experiences remain taboo within the field. This study documented high rates of mental-health difficulties (both diagnosed and undiagnosed) among faculty, graduate students, and others affiliated with accredited doctoral and internship programs in clinical, counseling, and school psychology. More than 80% of respondents ( = 1,395 of 1,692) reported a lifetime history mental-health difficulties, and nearly half (48%) reported a diagnosed mental disorder. Read More

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Geocultural variation in correlates of psychological distress among refugees resettled in the United States.

J Trauma Stress 2022 Jun 21. Epub 2022 Jun 21.

Department of Sociology, University of New Mexico, Albuquerque, New Mexico, USA.

Attention to cultural variability in mental health symptoms could inform intervention targets; however, this is currently a neglected area of study. This study examined whether the associations between common mental health disorder (CMD) symptoms and predictors of CMDs varied cross-culturally. Participants were 290 refugees from three geocultural regions (Afghanistan, Great Lakes region of Africa, and Iraq and Syria) who recently resettled in the United States and completed assessments of CMD symptoms and predictors. Read More

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Psychometric properties of the emotional processing scale in individuals with psychiatric symptoms and the development of a brief 15-item version.

Sci Rep 2022 Jun 21;12(1):10456. Epub 2022 Jun 21.

Department of Clinical Neuroscience, Karolinska Institutet, 171 65, Stockholm, Sweden.

The 25-item Emotional Processing Scale (EPS) can be used with clinical populations, but there is little research on its psychometric properties (factor structure, test-retest reliability, and validity) in individuals with psychiatric symptoms. We administered the EPS-25 to a large sample of people (N = 512) with elevated psychiatric symptoms. We used confirmatory factor analysis to evaluate three a priori models from previous research and then evaluated discriminant and convergent validity against measures of alexithymia (Toronto Alexithymia Scale-20), depressive symptoms (Patient Health Questionaire-9), and anxiety symptoms (Generalized Anxiety Disorder-7). Read More

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Validation of the Patient Health Questionnaire-4 (PHQ-4) to screen for depression and anxiety in the Greek general population.

J Psychosom Res 2022 Jun 16;160:110970. Epub 2022 Jun 16.

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece. Electronic address:

Objective: The Patient Health Questionnaire-4 (PHQ-4) is an ultra-brief self-report screening scale for depression and anxiety with promising psychometric properties; however, its reliability and validity have not been investigated in Greece yet. The objective of the current study was to investigate the reliability and validity of the PHQ-4 and to establish a cut-off score to identify depression and anxiety in the Greek general population.

Methods: The reliability of the PHQ-4 was assessed using a random sample of 204 students from Athens, Greece. Read More

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Substance use trajectories among urban college students: associations with symptoms of stress, anxiety, and depression before and during COVID-19.

J Am Coll Health 2022 Jun 21:1-10. Epub 2022 Jun 21.

Psychology Department, The City College of New York, New York, New York, USA.

This study explored substance use trajectories and associations with mental health among an ethnically/racially diverse college student sample before and during the COVID-19 pandemic. We combined repeated cross-sections and panel data from a total of 3,247 college students assessed with an online survey in 2018, 2019, and in three waves in 2020. We estimated trends in substance use and their relation to mental health over the survey waves using generalized estimating equations (GEE). Read More

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Contextual generalization of social stress learning is modulated by orexin receptors in basolateral amygdala.

Neuropharmacology 2022 Jun 17;215:109168. Epub 2022 Jun 17.

Department of Biology, University of South Dakota, Vermillion, SD, 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD, 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD, 57105, USA. Electronic address:

Fear-associated memories and behavior are often expressed in contexts/environments distinctively different from those in which they are created. This generalization process contributes to psychological disorders, particularly PTSD. Stress-related neurocircuits in the basolateral amygdala (BLA) receive inputs from hypothalamic orexin (Orx) neurons, which mediate neuronal activity by targeting orexin 1 (OrxR) and orexin 2 (OrxR) receptors via opposing functions. Read More

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Prevalence and Associated Factors of Diabetes Distress, Depression and Anxiety Among Primary Care Patients With Type 2 Diabetes During the COVID-19 Pandemic in Egypt: A Cross-Sectional Study.

Front Psychiatry 2022 3;13:937973. Epub 2022 Jun 3.

Department of Family Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

The prevalence of type 2 diabetes mellitus (T2DM) is growing worldwide. T2DM is often complicated by a range of psychological disorders that interfere with glycemic control and self-care. Previous studies have reported diabetes distress, depression, and anxiety among patients with T2DM; however; little is known about the burden of these comorbid mental disorders in primary care patients with T2DM treated in Egypt during the COVID-19 era. Read More

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