1,007,043 results match your criteria Gender Place and Culture [Journal]


Depression and Inflammation among Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer Patients.

Psychooncology 2019 Apr 25. Epub 2019 Apr 25.

Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY.

Objectives: Depression is highly prevalent in Non-Small Cell Lung cancer (NSCLC) and is associated with elevated inflammation. However, certain subtypes of driver mutation associated NSCLC such as Epidermal Growth Factor Receptor (EGFR) mutated NSCLC may be associated with less depression given the differences in their underlying biology and disease trajectories. Biological variables such as inflammation, measured by C-reactive protein (CRP), may provide insight into depression variability in EGFR mutant NSCLC. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pon.5097
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http://dx.doi.org/10.1002/pon.5097DOI Listing
April 2019
1 Read

The double burden of food insecurity and obesity among Latino youth: Understanding the role of generational status.

Pediatr Obes 2019 Apr 25:e12525. Epub 2019 Apr 25.

Department of Public Health Education, University of North Carolina, Greenboro, NC, USA.

Background: Obesity is linked to food insecurity and generational status; however, little is known about how both impact obesity risk among Latino youth.

Objective: To investigate the joint effect of generational status and food insecurity on obesity prevalence among Latino youth.

Methods: We pooled data from the 2011 to 2017 waves of the National Health Interview Survey to derive a sample Latino youth aged 12 to 17 (N = 7532). Read More

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http://dx.doi.org/10.1111/ijpo.12525DOI Listing

Assessment of the Relationship Between Serum High Molecular Weight Adiponectin Hormone Levels and Insulin Resistance in Patients with Polycystic Ovary Syndrome.

Horm Metab Res 2019 Apr 25;51(4):261-266. Epub 2019 Apr 25.

VKV American Hospital, Women's Healthcare Centre, Istanbul, Turkey.

The purpose of this study was to assess the rate of insulin resistance (IR) and the relationship between IR and high-molecular weight adiponectin (HMWA) in patients with polycystic ovary syndrome (PCOS). A cross sectional study involving 43 women with PCOS and 39 normal women was carried out over a period of nine months. Fasting glucose and insulin levels, lipid parameters and androgen levels were measured in all serum samples. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0867-0886
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http://dx.doi.org/10.1055/a-0867-0886DOI Listing
April 2019
2 Reads

Cotreatment of IGF1 and Fadrozole Upregulates the Expression of RSPO1, SOX9, and AMH in Chicken Embryos.

Cells Tissues Organs 2019 Apr 25:1-11. Epub 2019 Apr 25.

Transgenesis Center of Excellence, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran,

Insulin-like growth factor-1 (IGF1) and anti-aromatase synergistically increase the rate and stability of female-to-male sex reversal as well as pre- and postnatal weight gains in hatched chickens. This study aimed at assessing gene expression profiles of chicken embryos treated with IGF1 and fadrozole. Day 3. Read More

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http://dx.doi.org/10.1159/000499079DOI Listing

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study.

Redox Biol 2019 Apr 15;24:101204. Epub 2019 Apr 15.

Department of Physiology and Pharmacology, Sackler Medical School, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Recently, Weber et al. published a thorough investigation of the age-dependency of oxidative stress (OS) determined by the steady state concentrations of different compounds - oxidation products and antioxidants - that are in common use as biomarkers of OS in 2207 healthy individuals of the cross-sectional MARK-AGE Project. The correlations among biomarkers were significant but weak. Read More

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http://dx.doi.org/10.1016/j.redox.2019.101204DOI Listing

Microplastics biomonitoring in Australian urban wetlands using a common noxious fish (Gambusia holbrooki).

Chemosphere 2019 Apr 17;228:65-74. Epub 2019 Apr 17.

School of Biosciences, The University of Melbourne, Parkville, 3010, Victoria, Australia; Aquatic Environmental Stress Research Group (AQUEST), School of Science, RMIT University, PO Box 71, Bundoora, 3078, Australia.

Biomonitoring microplastics in freshwater ecosystems has been insufficient in comparison with its practice in marine environments. It is an important first step to understand microplastic uptake in organisms when assessing risk in natural freshwater habitats. We conducted microplastic biomonitoring within the Greater Melbourne Area; where the microplastic baseline pollution in freshwater organisms was largely unknown. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2019.04.114DOI Listing

Effect of presynchronization with prostaglandin F before the 5-d timed AI protocol on ovarian responses and pregnancy in dairy heifers.

Theriogenology 2019 Mar 23;132:138-143. Epub 2019 Mar 23.

Department of Animal Sciences and D. H. Barron Reproductive and Perinatal Biology Research Program, University of Florida, Gainesville, FL, 32611, Turkey. Electronic address:

The objectives were the determine the effects of presynchronization with PGF 2 days before the 5-d timed artificial insemination (AI) protocol on ovarian responses and pregnancy per AI (P/AI) in dairy heifers. The hypothesis was that PGF would induce responsive heifers to be in proestrus at the initiation of the timed AI protocol, which was expected to improve ovulatory responses and P/AI. Weekly cohorts of Holstein heifers were blocked by age and, within block, randomly assigned to remain as control (CON; n = 255) or receive PGF on experiment Day -10 (PG; n = 255). Read More

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http://dx.doi.org/10.1016/j.theriogenology.2019.03.019DOI Listing

Micro-geographic targeting for precision public policy: Analysis of child sex ratio across 587,043 census villages in India, 2011.

Health Place 2019 Apr 22;57:92-100. Epub 2019 Apr 22.

Harvard Center for Population and Development Studies, Cambridge, MA, USA; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address:

Child sex ratio (CSR) is a marker of disproportionate sex ratio at birth and discriminatory practices that lead to differential survival in early childhood by sex. We used the 2011 Census on rural India to present the first local analysis of CSR across 587,043 villages. In our multilevel analysis considering villages, tehsils, districts, and states/union territories, we found 96% of the total variation in CSR to be attributed to villages. Read More

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http://dx.doi.org/10.1016/j.healthplace.2019.02.005DOI Listing

microRNA expression profile in Smooth Muscle Cells isolated from thoracic aortic aneurysm samples.

Adv Med Sci 2019 Apr 22;64(2):331-337. Epub 2019 Apr 22.

Department of Medical Biology, Immunology Laboratory, Institute of Cardiology, Warsaw, Poland. Electronic address:

Purpose: Thoracic aortic aneurysm (TAA) is a cardiovascular disease characterized by increased aortic diameter, treated with surgery and endovascular therapy in order to avoid aortic dissection or rupture. The mechanism of TAA formation has not been thoroughly studied and many factors have been proposed to drive its progression; however strong focus is attributed to modification of smooth muscle cells (SMCs). Latest research indicates, that microRNAs (miRNAs) may play a significant role in TAA development - these are multifunctional molecules consisting of 19-24 nucleotides involved in regulation of the gene expression level related to many biological processes, i. Read More

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http://dx.doi.org/10.1016/j.advms.2019.04.003DOI Listing

Heterogeneity of treatment effects in a randomized trial of literacy-adapted group cognitive-behavioral therapy, pain psychoeducation, and usual medical care for multiply disadvantaged patients with chronic pain.

J Pain 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychology, The University of Alabama, Box 870348, Tuscaloosa, AL, 35487-0348, United States of America. Electronic address:

Differences among patients can moderate the impact of evidence-based treatments (i.e., heterogeneity of treatment effects), leading patients to get more or less benefit. Read More

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http://dx.doi.org/10.1016/j.jpain.2019.04.006DOI Listing

Toxicokinetics and bioavailability of bisphenol AF following oral administration in rodents: A dose, species, and sex comparison.

Toxicol Appl Pharmacol 2019 Apr 22. Epub 2019 Apr 22.

RTI International, Discovery Sciences, Research Triangle Park, NC, United States of America.

We investigated the toxicokinetics and bioavailability of bisphenol AF (BPAF) in male and female Harlan Sprague Dawley rats and B6C3F1/N mice following a single gavage administration of 34, 110, or 340 mg/kg. A validated analytical method was used to quantitate free (unconjugated parent) and total (unconjugated and conjugated) BPAF in plasma. BPAF was rapidly absorbed in rats with the maximum plasma concentration, C, of free BPAF reached at ≤2. Read More

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http://dx.doi.org/10.1016/j.taap.2019.04.015DOI Listing

Gender specific differences of immune competence in the sea cucumber Apostichopus japonicus before and after spawning.

Fish Shellfish Immunol 2019 Apr 22. Epub 2019 Apr 22.

Liaoning Key Lab of Marine Fishery Molecular Biology, Liaoning Ocean and Fisheries Science Research Institute, Dalian, Liaoning, 116023, PR China. Electronic address:

The gender differences of immunity have been elucidated in many vertebrates and invertebrates. However, the information of this difference was still not clear in the sea cucumber Apostichopus japonicus, which is one of the most valuable aquaculture species and susceptible to diseases caused by pathogen infection. In the present study, the transcriptome of coelomocytes from female and male A. Read More

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http://dx.doi.org/10.1016/j.fsi.2019.04.051DOI Listing

Nutritional status and body fat mass: Determinants of sarcopenia in community-dwelling older adults.

Exp Gerontol 2019 Apr 22. Epub 2019 Apr 22.

Nutrition Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Background: Sarcopenia is defined as the old age syndrome characterized by profound decline in muscle mass and function. This study aimed to investigate the prevalence of sarcopenia and its risk factors in older adults.

Methods: Totally, 501 older people aged 65 years and older were recruited. Read More

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http://dx.doi.org/10.1016/j.exger.2019.04.009DOI Listing

The role of gonadal hormones in the hypoglossal discharge activity of rats exposed to chronic intermittent hypoxia.

Brain Res Bull 2019 Apr 22. Epub 2019 Apr 22.

Division of Respiratory Disease, Renmin Hospital of Wuhan University, Zhangzhidong Road No. 99, Wuhan 430060, China. Electronic address:

Objective: The role of gonadal hormones in chronic intermittent hypoxia (CIH)-evoked hypoglossal nerve (XII) neuroplasticity has not been thoroughly studied. The purpose of this study was to reveal the effects of gonadal hormone concentration variations on the XII discharge activity of rats exposed to CIH and the corresponding relationship with 5-hydroxytryptamine (5-HT).

Methods: This study employed five groups of female rats and six groups of male rats. Read More

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http://dx.doi.org/10.1016/j.brainresbull.2019.04.017DOI Listing

Biological variation of peripheral blood T-lymphocytes.

J Immunol Methods 2019 Apr 22. Epub 2019 Apr 22.

Ankara Education and Trainning Hospital, Biochemistry Department, Ankara, Turkey.

Background: Flow cytometric analysis of the lymphocyte subsets has become one of the most commonly used techniques in the routine clinical laboratory. It is frequently used in monitoring lymphocyte recovery after hematopoietic stem cell transplantation (HSCT), as well as diagnosis and treatment of acquired immunodeficiency syndrome (AIDS). Reliable biological variation (BV) data is needed for safe clinical application of these tests. Read More

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http://dx.doi.org/10.1016/j.jim.2019.04.002DOI Listing

The Burden of Cerebrovascular Disease in the United States.

Prev Chronic Dis 2019 Apr 25;16:E52. Epub 2019 Apr 25.

Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.

Introduction: Little is known about trends in the overall combined burden of fatal and nonfatal cerebrovascular disease events in the United States. Our objective was to describe the combined burden by age, sex, and region from 2006 through 2014.

Methods: We used data on adults aged 35 and older from 2006 through 2014 Nationwide Emergency Department Sample, National Inpatient Sample of the Healthcare Cost and Utilization Project, and the National Vital Statistics System. Read More

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http://dx.doi.org/10.5888/pcd16.180411DOI Listing

Health Care Utilization and Mental Health Diagnoses Among Veterans With Tinnitus.

Am J Audiol 2019 Apr;28(1S):181-190

VA Rehabilitation Research & Development Service, National Center for Rehabilitative Auditory Research, VA Portland Health Care System, OR.

Purpose Tinnitus is prevalent among military Veterans and may frequently co-occur with mental health disorders. This study examined health care utilization and mental health diagnoses among Veterans with and without tinnitus who receive Department of Veterans Affairs (VA) health care. Method We randomly sampled 10% of VA health care users for a 5-year period between 2011 and 2016. Read More

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http://dx.doi.org/10.1044/2018_AJA-TTR17-18-0042DOI Listing

Perceptions and Attitudes toward Brain Donation among the Chinese People.

Anat Sci Educ 2019 Apr 25. Epub 2019 Apr 25.

Xiangya Brain Bank, School of Basic Medical Science, Central South University, Changsha, Hunan, People's Republic of China.

Postmortem human brain donation is crucial to both anatomy education and research. The China Human Brain Banking Consortium was established recently to foster brain donation in China. The purpose of this study was to gain information about the public perception of and attitudes toward brain donation and to identify factors that may impact the willingness to participate in brain donation among the Chinese people. Read More

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http://dx.doi.org/10.1002/ase.1886DOI Listing

Transfusion trends in hip arthroplasty in Korea: a nationwide study by the Korean National Health Insurance Service.

Transfusion 2019 Apr 25. Epub 2019 Apr 25.

Department of Pediatrics, SCH Biomedical Informatics Research Unit, Soonchunhyang University Hospital Seoul, Seoul, South Korea.

Background: Hip arthroplasties are strongly associated with blood transfusion to compensate for perioperative bleeding. The purpose of this study was to evaluate the trends in transfusion associated with hip arthroplasties, using nationwide data supplied by the National Health Insurance Service.

Study Design And Methods: We used data from nationwide claims database of the Health Insurance Review Assessment Service. Read More

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http://dx.doi.org/10.1111/trf.15330DOI Listing

Demographical, hematological and serological risk factors for Plasmodium falciparum gametocyte carriage in a high stable transmission zone in Cameroon.

PLoS One 2019 25;14(4):e0216133. Epub 2019 Apr 25.

Malaria Research Unit, Centre Pasteur Cameroon, Yaounde, Cameroon.

Presence of mature gametocyte forms of malaria parasites in peripheral blood is a key requirement for malaria transmission. Yet, studies conducted in most malaria transmission zones report the absence of gametocyte in the majority of patients. We therefore sought to determine the risk factors of both all-stage and mature gametocyte carriage in an area with high stable transmission of Plasmodium falciparum in Cameroon. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216133PLOS
April 2019
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Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS.

PLoS One 2019 25;14(4):e0215991. Epub 2019 Apr 25.

Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Background: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral therapy (ART). The exact contribution of T cells, natural killer (NK) cells, and monocytes to TB-IRIS development remains unclear. Here, we studied the expression of exhaustion markers on lymphocytes at different intervals during ART. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215991PLOS

Effect of proton pump inhibitors on mortality of cirrhotic patients with pneumonia.

PLoS One 2019 25;14(4):e0216041. Epub 2019 Apr 25.

Department of Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.

Objective: Pneumonia is life-threatening in patients with liver cirrhosis. Proton pump inhibitors (PPIs) may increase the risk of these patients developing pneumonia. However, whether PPIs increase mortality in patients with cirrhosis and pneumonia remain unknown. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216041PLOS
April 2019
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Rural-urban disparities in age trajectories of depression caseness in later life: The China Health and Retirement Longitudinal Study.

PLoS One 2019 25;14(4):e0215907. Epub 2019 Apr 25.

Laboratory of Population Health, Max Planck Institute for Demographic Research, Rostock, Germany.

Background: No consensus has been reached on whether depression decreases or increases with age in later life. Majority of the evidence comes from Western societies, while little is known about this relationship and its rural-urban disparities in the Chinese context.

Methods: Three waves of data from 15,501 Chinese adults aged 45-85 years from the China Health and Retirement Longitudinal Study, Chinese sister study of Health and Retirement Study, were used. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215907PLOS
April 2019
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Identifying obesity/overweight status in children and adolescents; A cross-sectional medical record review of physicians' weight screening practice in outpatient clinics, Saudi Arabia.

PLoS One 2019 25;14(4):e0215697. Epub 2019 Apr 25.

Department of Pediatrics and Adolescent Medicine, Aldara Hospital and Medical Center, Riyadh, Saudi Arabia.

Background: BMI is a feasible and recommended measure for overweight and obesity screening in children and adolescents. The study aimed to determine how often physicians correctly identified obesity/ overweight status in children and adolescents by using BMI percentile charts.

Methods: This retrospective cross-sectional study reviewed the paper medical records of children and adolescents (6-14 years) who visited family medicine and pediatric outpatient clinics (Jan-June 2012) in a medical city in Riyadh. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215697PLOS

Risk factors of neonatal sepsis in India: A systematic review and meta-analysis.

PLoS One 2019 25;14(4):e0215683. Epub 2019 Apr 25.

Department of Medical Biometrics & Informatics (Biostatistics), Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

Background: The incidence of neonatal sepsis in India is the highest in the world. Evidence regarding its risk factors can guide clinical practice and prevention strategies.

Objective: To review, assess and synthesize the available literature from India on the risk factors of sepsis among neonates. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215683PLOS

Electrolyte imbalances in an unselected population in an emergency department: A retrospective cohort study.

PLoS One 2019 25;14(4):e0215673. Epub 2019 Apr 25.

Department of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway.

Background: Although electrolyte imbalances (EIs) are common in the emergency department (ED), few studies have examined the occurrence of such conditions in an unselected population.

Objectives: To investigate the frequency of EI among adult patients who present to the ED, with regards to type and severity, and the association with age and sex of the patient, hospital length of stay (LOS), readmission, and mortality.

Methods: A retrospective cohort study. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215673PLOS

Underreported and unknown student harassment at the Faculty of Science.

PLoS One 2019 25;14(4):e0215067. Epub 2019 Apr 25.

Gender and Diversity Committee of the Faculty of Science of the Radboud University, Nijmegen, The Netherlands.

Reports of sexual harassment at medical faculties throughout the world, including the Radboud University, raised the question how prevalent this is at the Faculty of Science. We performed a survey among students to assess their experiences with harassment. This questionnaire consisted of questions from the EGERA survey, a questionnaire held among staff of multiple European Universities. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215067PLOS

Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies.

PLoS Biol 2019 Apr 25;17(4):e3000244. Epub 2019 Apr 25.

Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.

The evolution of sexual dimorphism is constrained by a shared genome, leading to 'sexual antagonism', in which different alleles at given loci are favoured by selection in males and females. Despite its wide taxonomic incidence, we know little about the identity, genomic location, and evolutionary dynamics of antagonistic genetic variants. To address these deficits, we use sex-specific fitness data from 202 fully sequenced hemiclonal Drosophila melanogaster fly lines to perform a genome-wide association study (GWAS) of sexual antagonism. Read More

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http://dx.doi.org/10.1371/journal.pbio.3000244DOI Listing

An Investigation of Brain Functional Connectivity by Form of Craniosynostosis.

J Craniofac Surg 2019 Apr 18. Epub 2019 Apr 18.

Section of Plastic and Reconstructive Surgery, Yale School of Medicine.

Purpose: Long-term neurocognitive sequelae of nonsyndromic craniosynostosis (NSC) patients are just beginning to be clarified. This study uses functional MRI (fMRI) to determine if there is evidence of altered brain functional connectivity in NSC, and whether these aberrations vary by form of synostosis.

Methods: Twenty adolescent participants with surgically treated NSC (10 sagittal synostosis, 5 right unilateral coronal synostosis [UCS], 5 metopic synostosis [MSO]) were individually matched to controls by age, gender, and handedness. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005537DOI Listing

The Electrical Activity of Masseter and Anterior Temporal Muscles in Patients with Unilateral Cleft Lip and Palate.

J Craniofac Surg 2019 Apr 20. Epub 2019 Apr 20.

Private Practice, Mashhad, Iran.

This study aimed to determine the electrical activity of masseter and anterior temporal muscles in patients with unilateral cleft lip and palate (CLP) and compare it with healthy volunteers. The study involved 20 female patients (mean age 20 ± 4 years) with unilateral cleft lip and palate who had undergone lip and palate surgery in childhood and finished the first-phase orthodontic therapy with level and align teeth. Twenty age- and sex-matched volunteers with no cleft lip and palate were involved as controls. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005560DOI Listing

Impact of Spotter Sex on One Repetition Maximum Bench Press Performance.

J Strength Cond Res 2019 Apr 23. Epub 2019 Apr 23.

Department of Health Sciences and Kinesiology, Georgia Southern University, Statesboro, Georgia.

Nickerson, BS, Salinas, G, Garza, JM, Cho, S, and Snarr, RL. Impact of spotter sex on one repetition maximum bench press performance. J Strength Cond Res XX(X): 000-000, 2019-Resistance exercise is popular because of favorable health outcomes associated with increased muscular fitness. Read More

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http://dx.doi.org/10.1519/JSC.0000000000003156DOI Listing

Predictors of Exercise Training and Physical Activity Adherence in People Recently Hospitalized With Heart Failure: A BRIEF REPORT.

J Cardiopulm Rehabil Prev 2019 May;39(3):E12-E16

Heart Support Service (Ms Adsett) and Departments of Physiotherapy (Ms Adsett) and Internal Medicine and Aged Care (Dr Mudge), Royal Brisbane and Women's Hospital, Brisbane, Australia; School of Allied Health Sciences, Griffith University, Gold Coast, Australia (Ms Adsett and Dr Morris); Menzies Health Institute, Queensland, Australia (Ms Adsett and Dr Morris); Metro North Hospital and Health Service, The Prince Charles Hospital, Allied Health Research Collaborative, Queensland, Australia (Dr Morris); and University of Queensland Faculty of Medicine, Brisbane, Queensland, Australia (Dr Mudge).

Purpose: For individuals with heart failure (HF), frequent attendance at exercise training programs and meeting physical activity (PA) guidelines are significantly associated with improvements in 6-min walk distance. Despite the evidence, adherence to exercise interventions remains poor. The aim of this study was to identify predictors of these 2 variables in patients recently hospitalized with HF. Read More

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http://dx.doi.org/10.1097/HCR.0000000000000407DOI Listing

Zumba Fitness and Women's Cardiovascular Health: A SYSTEMATIC REVIEW.

J Cardiopulm Rehabil Prev 2019 May;39(3):153-160

Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy (Drs Cugusi, Crisafulli, and Mercuro); Department of Biomedical Sciences, University of Sassari, Sassari, Italy (Dr Manca); Sport and Exercise Medicine Division, Department of Medicine, University of Padova, Padova, Italy (Dr Bergamin); Endocrine Section, Department of Medicine and Aging Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy (Dr Di Blasio); and Department of Cardiology, National University Heart Centre, Singapore, Singapore (Dr Yeo).

Purpose: Zumba fitness (ZF) is a well-known exercise program involving dance and fitness. Despite its increasing popularity, no analysis has been conducted on studies focusing on the cardiovascular (CV) profile of women who performed this activity. The aim of this systematic review is to provide insights into the impact of ZF on women's CV health. Read More

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http://dx.doi.org/10.1097/HCR.0000000000000326DOI Listing

The effect of cross-sex hormones on the quality of life, depression and anxiety of transgender individuals: a quantitative systematic review.

JBI Database System Rev Implement Rep 2019 Apr 23. Epub 2019 Apr 23.

University of San Francisco Gleeson Library, Geschke Center, University of San Francisco, San Francisco, USA.

Objective: The objective of the review was to evaluate the effectiveness of cross-sex hormone use in improving quality of life and the related measures of depression and anxiety in the transgender population versus no use of cross-sex hormones.

Introduction: Transgender medicine as a specialty is still in its infancy and is beginning to attract more primary care providers. The use of hormones to aid in gender transition is expected to provide benefit with regard to quality of life, but there have been few high-quality studies. Read More

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http://Insights.ovid.com/crossref?an=01938924-900000000-9992
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http://dx.doi.org/10.11124/JBISRIR-2017-003869DOI Listing
April 2019
1 Read

Barriers and Facilitators to Engaging African American Men Who Have Sex With Men in the HIV Care Continuum: A Theory-Based Qualitative Study.

J Assoc Nurses AIDS Care 2019 May-Jun;30(3):352-361

John B. Jemmott, III, PhD, is a Professor, Perelman School of Medicine and Annenberg School for Communication, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Jingwen Zhang, PhD, is an Assistant Professor, Department of Communication, University of California, Davis, Davis, California, USA. Mikia Croom, MSEd, is a Senior Research Coordinator, Center for Health Behavior & Communication Research, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Larry D. Icard, PhD, is a Professor, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA. Scott E. Rutledge, PhD, is an Associate Professor, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA. Ann O'Leary, PhD, is a Senior Behavioral Scientist, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

African American men who have sex with men (MSM) have high rates of HIV, but interventions are needed to address their low rates of engagement in the HIV care continuum. To identify modifiable factors potentially affecting such engagement, we conducted qualitative interviews guided by the Theory of Planned Behavior with 27 African American MSM who had participated in an HIV risk-reduction intervention trial. Qualitative analyses resulted in four overarching themes: stigma, concerns with health care providers (HCPs), social support, and logistical issues. Read More

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http://dx.doi.org/10.1097/JNC.0000000000000087DOI Listing
April 2019
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BLOOD CHROMIUM-COBALT LEVELS IN PATIENTS AFTER TOTAL KNEE ARTHROPLASTY AND THEIR EFFECT ON THE RETINAL NERVE FIBER LAYER AND MACULAR GANGLION CELL COMPLEX.

Retina 2019 Apr 17. Epub 2019 Apr 17.

Adıyaman Besni State Hospital.

Purpose: To study blood cobalt (Co) and chromium (Cr) levels in patients who have undergone total knee arthroplasty and their effect on the retinal nerve fiber layer and macular ganglion cell complex.

Methods: One hundred patients who had undergone total knee arthroplasty and 50 healthy individuals who had no implants were included in the study. The patients were separated into two groups based on how long ago the prosthesis had been implanted (Group 1: 1 to 5 years; Group 2: 5 to 10 years). Read More

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http://dx.doi.org/10.1097/IAE.0000000000002535DOI Listing

Characterizing Social and Academic Aspects of School Anxiety in Pediatric Chronic Pain.

Clin J Pain 2019 Apr 23. Epub 2019 Apr 23.

Department of Psychology, University of Cincinnati.

Objective: School anxiety is a prevalent and debilitating mental health problem among youth with chronic pain. Despite evidence that anxiety in the context of school is associated with significant school-related disability, no studies have examined specific aspects of school anxiety in a pediatric chronic pain population.

Methods: Adolescents with chronic pain (n=30) and age- and gender-matched controls (n=30) and their parents completed questionnaires assessing school anxiety and functioning. Read More

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http://dx.doi.org/10.1097/AJP.0000000000000720DOI Listing

Acts Committed and Omitted: Acknowledging Racial and Gender Bias in Medicine.

Authors:
Sandhya Rao

Acad Med 2019 May;94(5):610

Fourth-year medical student, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire; ORCID: https://orcid.org/0000-0002-5782-951X.

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http://dx.doi.org/10.1097/ACM.0000000000002655DOI Listing

Breast Reduction Following Hormonal Therapy in a Transgender Female Patient.

Ann Plast Surg 2019 Apr 22. Epub 2019 Apr 22.

From the Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.

In male-to-female gender transition, individuals request a number of interventions, including hormonal therapy, to promote feminizing characteristics. Estrogen-based medication is prescribed to increase breast development, decrease facial hair, promote feminine adipose tissue deposition, and soften skin. Surgical breast augmentation to supplement unsatisfying breast growth after hormonal therapy is a common and well-studied course of management for such transgender patients. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001855DOI Listing

Risk of Mortality and Hospitalization After Post-Pancreatitis Diabetes Mellitus vs Type 2 Diabetes Mellitus: A Population-Based Matched Cohort Study.

Am J Gastroenterol 2019 Apr 22. Epub 2019 Apr 22.

School of Medicine, University of Auckland, Auckland, New Zealand.

Objectives: To investigate the risk of mortality and hospitalization in individuals with post-pancreatitis diabetes mellitus (PPDM) compared with those with type 2 diabetes mellitus (T2DM).

Methods: Using nationwide hospital discharge data on pancreatitis and diabetes in New Zealand (n = 231,943), a total of 959 individuals with PPDM were identified. For each individual with PPDM, 10 age- and sex-matched individuals with T2DM were randomly selected. Read More

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http://dx.doi.org/10.14309/ajg.0000000000000225DOI Listing

Translocation Frequency in Patients with Repeated CT Exposure: Comparison with CT-Naive Patients.

Radiat Res 2019 Apr 25. Epub 2019 Apr 25.

d   Department of Biostatistics, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea.

Epidemiologic studies using clinical indicators are limited in the assessment of the biological effects of low-dose ionizing radiation for medical purposes. We evaluated the biological effect of low-dose radiation by comparing translocation frequencies in patients with repeated computed tomography (CT) exposure and CT-naïve patients. The goal of this prospective case-control study was to determine whether repeated CT exposure is associated with increased frequency in chromosomal translocations. Read More

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http://www.rrjournal.org/doi/10.1667/RR15286.1
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http://dx.doi.org/10.1667/RR15286.1DOI Listing
April 2019
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Reference Values for Healthy Swallowing Across the Range From Thin to Extremely Thick Liquids.

J Speech Lang Hear Res 2019 Apr 25:1-26. Epub 2019 Apr 25.

Swallowing Rehabilitation Research Laboratory, Toronto Rehabilitation Institute, University Health Network, Ontario, Canada.

Purpose Thickened liquids are frequently used as an intervention for dysphagia, but gaps persist in our understanding of variations in swallowing behavior based on incremental thickening of liquids. The goal of this study was to establish reference values for measures of bolus flow and swallowing physiology in healthy adults across the continuum from thin to extremely thick liquids. Method A sex-balanced sample of 38 healthy adults underwent videofluoroscopy and swallowed 20% weight-to-volume concentration barium prepared in thin and slightly, mildly, moderately, and extremely thick consistencies using a xanthan gum thickener. Read More

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http://dx.doi.org/10.1044/2019_JSLHR-S-18-0448DOI Listing

Romiplostim (Nplate®) as an Effective Radiation Countermeasure to Improve Survival and Platelet Recovery in Mice.

Int J Radiat Biol 2019 Apr 25:1-29. Epub 2019 Apr 25.

a SRI Biosciences, SRI International , Menlo Park , CA USA.

Purpose: Rapid depletion of white blood cells, platelets, and reticulocytes are hallmarks of hematopoietic injury of acute radiation syndrome (H-ARS) and, if left untreated, can lead to severe health consequences including death. While the granulocyte colony stimulating factors (G-CSF) filgrastim (Neupogen®), pegfilgrastim (Neulasta®), and sargramostim (Leukine®) are approved to increase survival in patients exposed to a myelosuppressive dose of radiation, no medical countermeasure is currently available for treatment of the thrombocytopenia that also results following radiation exposure. Romiplostim (Nplate®), a thrombopoietin receptor agonist, is the first FDA-approved thrombopoiesis-stimulating protein for the treatment of low platelet (PLT) counts in adults with chronic immune thrombocytopenia. Read More

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http://dx.doi.org/10.1080/09553002.2019.1605465DOI Listing

The influence of online video learning aids on preparing postgraduate chiropractic students for an objective structured clinical examination.

J Chiropr Educ 2019 Apr 25. Epub 2019 Apr 25.

Objective: To investigate the influence of providing online procedural videos to postgraduate chiropractic students preparing for an objective structured clinical examination (OSCE).

Methods: Eighty-three postgraduate chiropractic students enrolled in a diagnostic unit during 2017 received supplemental video resources prior to their final OSCE. Ninety students enrolled in the 2016 offering of the unit acted as the control group. Read More

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http://dx.doi.org/10.7899/JCE-18-8DOI Listing

Relationship between Caregivers' Oral Health Literacy and their Child's Caries Experience.

Community Dent Health 2019 Apr 23. Epub 2019 Apr 23.

Department of Preventive Dentistry, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

Objective: This study aimed to assess the association between caregivers' oral health literacy (OHL) and the dental caries experience of their child.

Participants: This cross-sectional study was conducted among 300 caregiver/child dyads at a paediatric dental centre in Saudi Arabia. The OHL was assessed using an Arabic translated version of Comprehensive Measure of Oral Health Knowledge (CMOHK-A) questionnaire. Read More

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http://dx.doi.org/10.1922/CDH_4444Baskaradoss07DOI Listing

Differences in practice of ophthalmology by gender in Australia.

Clin Exp Ophthalmol 2019 Apr 25. Epub 2019 Apr 25.

The Royal Victorian Eye & Ear Hospital, East Melbourne VIC 3002, Australia.

Importance: The number of females practising ophthalmology is rising. It is known that practice patterns between female and male ophthalmologists differ. Understanding the differences will help to inform future workforce planning. Read More

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http://dx.doi.org/10.1111/ceo.13523DOI Listing

Uptake into a bedside needle and syringe program for acute care inpatients who inject drugs.

Drug Alcohol Rev 2019 Apr 25. Epub 2019 Apr 25.

Inner City Health and Wellness Program, Royal Alexandra Hospital, Edmonton, Canada.

Introduction And Aims: Injection drug use is associated with significant morbidity and mortality worldwide. Needle and syringe programs (NSP) have been shown to reduce negative health outcomes for people who inject drugs. However, NSPs have limited reach in hospitals, and no peer-reviewed research has examined NSP implementation in acute care settings. Read More

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http://dx.doi.org/10.1111/dar.12930DOI Listing

Models of Variability and Circadian Rhythm in Heart Rate, Blood Pressure and QT Interval for Healthy Subjects Who Received Placebo in Phase 1 Trials.

Clin Transl Sci 2019 Apr 25. Epub 2019 Apr 25.

Clinical Pharmacology and Pharmacometrics, AbbVie, 1 North Waukegan Road, Bldg AP31, North Chicago, IL, 60064.

This work characterized the time-course, circadian rhythm and inherent variability in key cardiovascular variables (heart rate, corrected QT interval, systolic and diastolic blood pressure) that are routinely collected as part of safety monitoring in Phase 1 trials. Longitudinal data from 1035 healthy volunteers who received placebo in 65 single- and multiple-dose Phase 1 trials conducted by AbbVie were compiled and analyzed using non-linear mixed-effects modeling. An independent non-linear mixed-effects model was developed for each variable and combinations of cosine functions were utilized to capture circadian oscillations. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cts.12640
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http://dx.doi.org/10.1111/cts.12640DOI Listing
April 2019
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