2,512 results match your criteria Gastroschisis


Multidisciplinary Development of a Low-cost Gastroschisis Silo for Use in Sub-Saharan Africa.

J Surg Res 2020 Jul 6;255:565-574. Epub 2020 Jul 6.

Department of Surgery, Duke University, Durham, North Carolina; Duke Global Health Institute, Duke University, Durham, North Carolina. Electronic address:

Background: Gastroschisis silos are often unavailable in sub-Saharan Africa (SSA), contributing to high mortality. We describe a collaboration between engineers and surgeons in the United States and Uganda to develop a silo from locally available materials.

Methods: Design criteria included the following: < $5 cost, 5 ± 0. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.037DOI Listing
July 2020
1.936 Impact Factor

Major birth defects in the Brazilian side of the triple border: a population-based cross-sectional study.

Arch Public Health 2020 30;78:61. Epub 2020 Jun 30.

Latin-American Institute of Life and Natural Sciences, Federal University of Latin-American Integration, Foz do Iguassu, Parana Brazil.

Background: Major birth defects increase the risk of fetal death and pediatric hospitalization, which also impact on healthcare costs. Sociodemographic factors can drastically affect reproductive health and be used to discriminate the exposure to hidden risk factors. Foz do Iguassu is a Brazilian city located in the triple-border region of Brazil / Paraguay / Argentina with high rates of birth defects. Read More

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http://dx.doi.org/10.1186/s13690-020-00443-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325680PMC

Prenatal sonography of extracorporeal ductus venosus in association with large fetal gastroschisis.

J Clin Ultrasound 2020 Jun 29. Epub 2020 Jun 29.

The Division of Maternal Fetal Medicine, The Department of Obstetrics and Gynecology, State University of New York (SUNY), Downstate Heath Sciences University, Brooklyn, New York, USA.

Liver herniation commonly associated with omphalocele occurs in only approximately 2.3% to 16% of fetuses with gastroschisis. Liver herniation in such cases is associated with considerably decreased survival rates (43% vs 97% with or without liver herniation, respectively). Read More

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http://dx.doi.org/10.1002/jcu.22881DOI Listing

Approaches for Closing Gastroschisis.

Adv Pediatr 2020 Aug 12;67:123-129. Epub 2020 May 12.

Department of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA; University of Missouri Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yapd.2020.03.005DOI Listing

Pediatric Surgery Simulation-Based Training for the General Surgery Resident.

J Surg Res 2020 Jun 16. Epub 2020 Jun 16.

Division of Pediatric Surgery, Department of Surgery, Rush University Medical Center, Chicago, Illinois; Rush Center For Clinical Skills and Simulation, Rush University Medical Center, Chicago, Illinois.

Background: Surgical simulation-based training (SBT) can increase resident confidence and improve performance. SBT in pediatric surgery is in its infancy and often geared toward training pediatric surgery fellows. Since case volume for various pediatric surgery-specific procedures can be low based on the rarity of the pathology involved and the level of care provided by the institution, our aim was to create a pediatric surgery simulation-based curriculum for general surgery residents to address this need. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.038DOI Listing

Mortality from gastroschisis in the state of Rio de Janeiro: a 10-year series.

Rev Saude Publica 2020 12;54:63. Epub 2020 Jun 12.

Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.

Objective: To analyze mortality and associated factors in a series of gastroschisis at birth in the state of Rio de Janeiro in a 10-year period (2005 to 2014).

Method: A retrospective cohort study, which related the databases of the Live Births Information System and the Mortality Information System by probabilistic linkage. Final database was constructed in two stages: preparation of the two initial databases and establishment of relationships between them. Read More

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http://dx.doi.org/10.11606/s1518-8787.2020054001757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274210PMC

Reply.

Am J Obstet Gynecol 2020 Jun 10. Epub 2020 Jun 10.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Medical Sciences Building, Room 4407, 231 Albert Sabin Way, Cincinnati, OH 45267-0526. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.010DOI Listing

Maternal occupational exposure to solvents and gastroschisis in offspring: are gene-environment interactions playing a role?

Occup Environ Med 2020 Jun 8. Epub 2020 Jun 8.

School of Public Health, Nantong University, Nantong, Jiangsu Province, China.

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http://dx.doi.org/10.1136/oemed-2020-106627DOI Listing

Abdominal Wall Defects.

Neoreviews 2020 Jun;21(6):e383-e391

Division of Pediatric Surgery, Children's Hospital, University of Missouri, Columbia, MO.

The 2 most common congenital abdominal wall defects are gastroschisis and omphalocele. Both are usually diagnosed prenatally with fetal ultrasonography, and affected patients are treated at a center with access to high-risk obstetric services, neonatology, and pediatric surgery. The main distinguishing features between the 2 are that gastroschisis has no sac and the defect is to the right of the umbilicus, whereas an omphalocele typically has a sac and the defect is at the umbilicus. Read More

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http://dx.doi.org/10.1542/neo.21-6-e383DOI Listing

Gastroschisis in the neonatal period: A prospective case-series in a Brazilian referral center.

J Pediatr Surg 2020 Apr 29. Epub 2020 Apr 29.

Clinical Research Unit, Instituto Fernandes Figueira - Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.

Background/purpose: Gastroschisis is increasing in incidence and has low mortality and high morbidity. We describe the clinical and surgical characteristics of gastroschisis patients in a Brazilian referral center.

Methods: Single-center prospective case series of gastroschisis patients. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.04.011DOI Listing

Impact of Clinical Factors on the Intestinal Microbiome in Infants With Gastroschisis.

JPEN J Parenter Enteral Nutr 2020 May 22. Epub 2020 May 22.

Department of Pediatrics, Neonatal Research Center of the UCLA of Children's Discovery and Innovation Institute, David Geffen School of Medicine UCLA and UCLA Mattel Children's Hospital, Los Angeles, California, USA.

Background: Infants with gastroschisis require operations and lengthy hospitalizations due to intestinal dysmotility. Dysbiosis may contribute to these problems. Little is known on the microbiome of gastroschisis infants. Read More

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http://dx.doi.org/10.1002/jpen.1926DOI Listing

Intraoperative Findings Associated to Inpatient Mortality From Patients With Gastroschisis in Western Mexico.

J Surg Res 2020 May 14;254:58-63. Epub 2020 May 14.

Pediatrics Division, Service of Pediatric Surgery, Dr Juan I. Menchaca Civil Hospital of Guadalajara, Guadalajara, Jalisco, Mexico.

Background: Intraoperative findings during gastroschisis surgery are the main predictor associated with increased mortality. The aim of our study was to determine the type of surgical findings associated with inpatient mortality in a cohort of patients with gastroschisis from a university hospital in Western Mexico.

Materials And Methods: Infants with surgically repaired gastroschisis during the period 2011-2017 at the Dr. Read More

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http://dx.doi.org/10.1016/j.jss.2020.03.065DOI Listing

Maternal risk factors for gastroschisis: A population-based case-control study.

Birth Defects Res 2020 May 14. Epub 2020 May 14.

Department of Paediatric Surgery and Orthopaedics, University of Turku and Turku University Hospital, Turku, Finland.

Background: Gastroschisis is an open abdominal wall defect with low mortality but significant morbidity. The prevalence has been increasing worldwide for the past decades. Several risk factors for gastroschisis have been identified, but no clear reason for increasing prevalence has been found. Read More

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http://dx.doi.org/10.1002/bdr2.1703DOI Listing

Antenatal corticosteroids and outcomes in gastroschisis: A multicenter retrospective cohort study.

Prenat Diagn 2020 Jul 24;40(8):991-997. Epub 2020 May 24.

UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital for Children, London, UK.

Objective: In gastroschisis, there is evidence to suggest that gut dysfunction develops secondary to bowel inflammation; we aimed to evaluate the effect of maternal antenatal corticosteroids administered for obstetric reasons on time to full enteral feeds in a multicenter cohort study of gastroschisis infants.

Methods: A three center, retrospective cohort study (1992-2013) with linked fetal/neonatal gastroschisis data was conducted. The primary outcome measure was time to full enteral feeds (a surrogate measure for bowel function) and secondary outcome measure was length of hospital stay. Read More

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http://dx.doi.org/10.1002/pd.5727DOI Listing

Extra-abdominal Cryptorchidism Associated With Gastroschisis and Impacted Urethral Calculus: Two Uncommon Urologic Conditions in One Patient.

Urology 2020 Apr 19. Epub 2020 Apr 19.

Pediatric Surgery Unit, Sapienza University of Rome, AOU Policlinico Umberto I, Rome, RM, Italy. Electronic address:

The testis is rarely encountered within the organs prolapsed outside the abdominal wall defect of patients with gastroschisis. Optimal treatment strategy of this unusual type of cryptorchidism remains undefined, with less than 30 cases reported to date. We describe a new case where simple relocation of the testis into the abdomen was followed by spontaneous testicular descent. Read More

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http://dx.doi.org/10.1016/j.urology.2020.04.034DOI Listing

Utility of Formulas Using Fetal Thigh Soft Tissue Thickness in Estimating Weight in Gastroschisis.

J Ultrasound Med 2020 Apr 22. Epub 2020 Apr 22.

Radiology, University of Washington, Seattle, Washington, USA.

Objectives: To evaluate the utility of the fetal thigh soft tissue thickness (STT) in calculating the estimated fetal weight (EFW) in fetuses with gastroschisis versus the standard formula of Hadlock et al (Am J Obstet Gynecol 1985; 151:333-337) compared to the actual birth weight (ABW).

Methods: A retrospective study of neonates born with gastroschisis delivered at our institution was performed. Two reviewers measured the fetal thigh STT on saved images. Read More

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http://dx.doi.org/10.1002/jum.15302DOI Listing

Accuracy of sonographic estimation of weight in fetuses with abdominal wall defects.

Aust N Z J Obstet Gynaecol 2020 Apr 14. Epub 2020 Apr 14.

Fetal Diagnostic Unit, Monash Health, Melbourne, Victoria, Australia.

Background: Accurate estimation of fetal weight is essential in guiding management of fetuses with abdominal wall defects (AWDs), as growth restriction is an important predictor of perinatal morbidity and mortality. Several sonographic formulae are available involving multiple biometric parameters, but abdominal circumference measurements may underestimate weight in fetuses with AWDs. No formula has yet shown superior accuracy. Read More

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http://dx.doi.org/10.1111/ajo.13162DOI Listing

Gastroschisis prevalence substantially decreased from 2009 through 2018 after a 3-fold increase from 1997 to 2008.

J Pediatr Surg 2020 Mar 24. Epub 2020 Mar 24.

Division of Neonatology, Department of Pediatrics, Baylor University Medical Center and Pediatrix Medical Group, Dallas, TX. Electronic address:

Background/purpose: Gastroschisis incidence increased 300% in the United States from 1998 to 2013. We sought to assess trends in gastroschisis prevalence in the United States from 1997 to 2018 from a large NICU dataset.

Methods: We performed a retrospective review of all infants in the Pediatrix Clinical Data Warehouse from 1997 to 2018. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.03.010DOI Listing

Erratum: Challenges and Outcome of Management of Gastroschisis at a Tertiary Institution in North-Eastern Nigeria.

Authors:

Front Surg 2020;7:15. Epub 2020 Mar 24.

[This corrects the article on p. 8 in vol. 7, PMID: 32195264. Read More

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http://dx.doi.org/10.3389/fsurg.2020.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105893PMC

Congenital multiple colonic atresias with intestinal malrotation: a case report.

Surg Case Rep 2020 Mar 30;6(1):60. Epub 2020 Mar 30.

Department of Pediatric Surgery, Asahikawa Medical University, 2-1-1, Midorigaoka-higashi Asahikawashi, Hokkaido, 078-8510, Japan.

Background: Congenital intestinal atresia develops in 1 in 1500 to 20,000 births. Colonic atresia, which accounts for 1.8-15% of intestinal atresia cases, is accompanied by other gastrointestinal atresias such as small intestinal atresia, gastroschisis, imperforate anus, and intestinal malformation in 47-80%. Read More

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http://dx.doi.org/10.1186/s40792-020-00822-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105550PMC

Decentralized surgery of abdominal wall defects in Germany.

Pediatr Surg Int 2020 May 26;36(5):569-578. Epub 2020 Mar 26.

Department of Pediatric Surgery and Pediatric Urology, University Hospital, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.

Purpose: Neonatal surgery for abdominal wall defects is not performed in a centralized manner in Germany. The aim of this study was to investigate whether treatment for abdominal wall defects in Germany is equally effective compared to international results despite the decentralized care.

Methods: All newborn patients who were clients of the major statutory health insurance company in Germany between 2009 and 2013 and who had a diagnosis of gastroschisis or omphalocele were included. Read More

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http://dx.doi.org/10.1007/s00383-020-04647-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165189PMC

Use of Human Umbilical Cord and Its Byproducts in Tissue Regeneration.

Front Bioeng Biotechnol 2020 10;8:117. Epub 2020 Mar 10.

Colegio de Ciencias de la Salud, Escuela de Medicina, Universidad San Francisco de Quito, Quito, Ecuador.

The fresh or cryopreserved human umbilical cord (HUC) and its byproducts, such as cells and extracts, have different uses in tissue regeneration. Defining what HUC byproduct is more effective in a particular application is a challenge. Furthermore, the methods of isolation, culture and preservation, may affect cell viability and regenerative properties. Read More

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http://dx.doi.org/10.3389/fbioe.2020.00117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075856PMC

Major abdominal wall defects in the low- and middle-income setting: current status and priorities.

Pediatr Surg Int 2020 May 21;36(5):579-590. Epub 2020 Mar 21.

Department of Paediatric Surgery and Paediatric Urology, University Hospital Frankfurt/M., Theodor-Stern-Kai 7, 60598, Frankfurt, Germany.

Major congenital abdominal wall defects (gastroschisis and omphalocele) may account for up to 21% of emergency neonatal interventions in low- and middle-income countries. In many low- and middle-income countries, the reported mortality of these malformations is 30-100%, while in high-income countries, mortality in infants with major abdominal wall reaches less than 5%. This review highlights the challenges faced in the management of newborns with major congenital abdominal wall defects in the resource-limited setting. Read More

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http://dx.doi.org/10.1007/s00383-020-04638-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165143PMC

Variation in hospital costs for gastroschisis closure techniques.

Am J Surg 2020 05 9;219(5):764-768. Epub 2020 Mar 9.

University of Washington School of Medicine, Seattle, WA, 98195, USA; Seattle Children's Hospital, Seattle, WA, 98105, USA. Electronic address:

Background: In newborns with gastroschisis, both primary repair and delayed fascial closure with initial silo placement are considered safe with similar outcomes although cost differences have not been explored.

Methods: A retrospective review was performed of newborns admitted with gastroschisis at a single center from 2011 to 2016. Demographic, clinical, and cost data during the initial hospitalization were collected. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2020.03.003DOI Listing

Epidemiology and outcomes of gastroschisis in Tasmania.

J Paediatr Child Health 2020 Mar 20. Epub 2020 Mar 20.

Department of Neonatal and Paediatric Intensive Care Unit (NPICU), Royal Hobart Hospital, Hobart, Tasmania, Australia.

Aim: To describe the epidemiology and outcomes of gastroschisis in Tasmania.

Methods: A retrospective analysis of all pregnancies complicated by gastroschisis in Tasmania from 1996 to 2015 was undertaken (epidemiology cohort), and the presentation, surgical management and outcomes (surgery cohort) were reviewed for the period between September 1990 and July 2015.

Results: Gastroschisis was detected in 58 pregnancies during the 20-year epidemiology cohort period, giving an incidence of 4. Read More

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http://dx.doi.org/10.1111/jpc.14863DOI Listing

Challenges and Outcome of Management of Gastroschisis at a Tertiary Institution in North-Eastern Nigeria.

Front Surg 2020 4;7. Epub 2020 Mar 4.

Division of Pediatric Surgery, Department of Surgery, Federal Medical Center, Yola, Nigeria.

Gastroschisis is a congenital anterior abdominal wall defect characterized by herniation of abdominal contents through a defect usually located to the right side of the umbilical cord. It occurs in about 1 in 2,000-4,000 live births and is slightly commoner in males. Management has remained challenging in the low and middle-income countries (LMICS), with high mortality rates. Read More

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http://dx.doi.org/10.3389/fsurg.2020.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064440PMC

Canadian Cannabis Consumption and Patterns of Congenital Anomalies: An Ecological Geospatial Analysis.

J Addict Med 2020 03 13. Epub 2020 Mar 13.

Division of Psychiatry, University of Western Australia, Crawley, Western Australia, Australia (ASR, GKH); School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia (ASR, GKH).

Objectives: Cannabis is a known teratogen. Data availability addressing both major congenital anomalies and cannabis use allowed us to explore their geospatial relationships.

Methods: Data for the years 1998 to 2009 from Canada Health and Statistics Canada was analyzed in R. Read More

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http://dx.doi.org/10.1097/ADM.0000000000000638DOI Listing

Determining maternal risk factors for gastroschisis using colorado's birth registry database.

J Pediatr Surg 2020 Jun 28;55(6):1002-1005. Epub 2020 Feb 28.

Colorado Fetal Care Center, Children's Hospital Colorado, Denver, CO.

Aim Of Study: Gastroschisis is a congenital abdominal wall defect which results in herniation of abdominal contents. The objective of this study was to determine the maternal risk factors for gastroschisis in Colorado.

Methods: A case-control study was performed using the Birth Registry database from 2007 to 2016. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.02.030DOI Listing

Growth from Birth to 30 months for Infants Born with Congenital Gastrointestinal Anomalies and Disorders.

Am J Perinatol 2020 Mar 13. Epub 2020 Mar 13.

Division of Neonatology and Developmental Biology, Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Mattel Children's Hospital at UCLA, Los Angeles, California.

Objective:  This study aimed to investigate growth among neonates with gastrointestinal disorders.

Study Design:  Inclusion criteria included neonates with gastroschisis, omphalocele, intestinal atresia, tracheoesophageal fistula, Hirschsprung's disease, malabsorption disorders, congenital diaphragmatic hernia, and imperforate anus born between 2010 and 2018. Anthropometrics were collected for the first 30 months, and a subgroup analysis was performed for gastroschisis infants. Read More

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http://dx.doi.org/10.1055/s-0040-1705136DOI Listing

Factors Related to the Development of Small-Bowel Bacterial Overgrowth in Pediatric Intestinal Failure: A Retrospective Cohort Study.

JPEN J Parenter Enteral Nutr 2020 Mar 13. Epub 2020 Mar 13.

Transplant and Regenerative Medicine Centre, Toronto, Canada.

Background: Small bowel bacterial overgrowth (SBBO) is a challenge in the management of pediatric intestinal failure (PIF). Our goal was to determine the proportion of patients treated for SBBO and factors related to its development.

Methods: We completed a retrospective analysis of PIF patients referred between 2008 and 2014. Read More

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http://dx.doi.org/10.1002/jpen.1809DOI Listing

Whole exome sequencing identifies multiple novel candidate genes in familial gastroschisis.

Mol Genet Genomic Med 2020 May 12;8(5):e1176. Epub 2020 Mar 12.

Department of Genetics, School of Medicine and University Hospital Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, México.

Background: Genetic association studies for gastroschisis have highlighted several candidate variants. However, genetic basis in gastroschisis from noninvestigated heritable factors could provide new insights into the human biology for this birth defect. We aim to identify novel gastroschisis susceptibility variants by employing whole exome sequencing (WES) in a Mexican family with recurrence of gastroschisis. Read More

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http://dx.doi.org/10.1002/mgg3.1176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216806PMC

Sutureless vs sutured abdominal wall closure for gastroschisis: Operative characteristics and early outcomes from the Midwest Pediatric Surgery Consortium.

J Pediatr Surg 2020 Feb 20. Epub 2020 Feb 20.

Department of Surgery, Children's Mercy Kansas City, Kansas City, MO.

Purpose: To report outcomes of sutured and sutureless closure for gastroschisis across a large multi-institutional cohort.

Methods: A retrospective study of infants with uncomplicated gastroschisis at 11 children's from 2014 to 2016 was performed. Outcomes of sutured and sutureless abdominal wall closure were compared. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.02.017DOI Listing
February 2020

Development of a prenatal clinical care pathway for uncomplicated gastroschisis and literature review.

J Neonatal Perinatal Med 2020 Mar 5. Epub 2020 Mar 5.

Department of Obstetrics/Gynecology, Division of Maternal-Fetal Medicine, University of Washington Medical Center, Seattle, WA, USA.

Background: Gastroschisis is an abdominal wall defect wherein the bowel is herniated into the amniotic fluid. Controversy exists regarding optimal prenatal surveillance strategies that predict fetal well-being and help guide timing of delivery. Our objective was to develop a clinical care pathway for prenatal management of uncomplicated gastroschisis at our institution. Read More

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http://dx.doi.org/10.3233/NPM-190277DOI Listing

Body Wall Defects: Gastroschisis and Omphalocoele in Pigs (Sus scrofa domesticus).

J Comp Pathol 2020 Feb 23;175:69-74. Epub 2020 Jan 23.

Clínica Veterinaria Salud Animal, Griñón, Madrid, Spain; Departmental Section of Anatomy and Embryology, School of Veterinary Medicine, Universidad Complutense de Madrid, Avda. Puerta de Hierro s/n, Madrid, Spain.

Body wall defects (BWDs) are not well studied and categorized in veterinary medicine. BWDs can be an isolated occurrence, but often occur with other major developmental abnormalities. Thirty-two body wall malformations of domestic pigs (Sus scrofa domesticus) are presented and classified, distinguishing between body wall dysplasia (umbilical hernia, abdominal wall distension and gastroschisis), omphalocoele and thoracoabdominoschisis (Cantrell syndrome, shistosomus reflexus, body stalk anomalies). Read More

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http://dx.doi.org/10.1016/j.jcpa.2019.12.003DOI Listing
February 2020

Risk factors for gastroschisis: A case-control study in a Brazilian population.

Int J Gynaecol Obstet 2020 Jun 31;149(3):347-353. Epub 2020 Mar 31.

Department of Obstetrics and Gynecology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Objective: To evaluate risk factors associated with fetal gastroschisis.

Methods: As a secondary aim of a larger case-control study, pregnant women attending the Fetal Medicine Unit at the Department of Obstetrics and Gynecology at Hospital das Clinicas, Sao Paulo University Medical School between July 1, 2013, and July 31, 2015, were allocated into either the gastroschisis group, where the woman was carrying a fetus with gastroschisis, or the control group, where the fetus was normal. Patients in the control group were matched at study entry for maternal age, preconception body mass index and weeks of gestation. Read More

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http://dx.doi.org/10.1002/ijgo.13135DOI Listing

Closing gastroschisis, vanishing midgut syndrome and intra-abdominal volvulus presenting with haematemesis at birth.

BMJ Case Rep 2020 Feb 26;13(2). Epub 2020 Feb 26.

Department of Pediatric Surgery, Bristol Royal Hospital for Children, Bristol, UK

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http://dx.doi.org/10.1136/bcr-2019-232757DOI Listing
February 2020

Supplementation of Mother's Own Milk with Donor Milk in Infants with Gastroschisis or Intestinal Atresia: A Retrospective Study.

Nutrients 2020 Feb 24;12(2). Epub 2020 Feb 24.

Department of Paediatrics, Division of Neonatology, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.

Background: Mother's own milk (MOM) improves in-hospital outcomes for preterm infants. If unavailable, donor milk (DM) is often substituted. It is unclear if DM vs. Read More

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http://dx.doi.org/10.3390/nu12020589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071452PMC
February 2020

Fetoscopic techniques for prenatal covering of gastroschisis in an ovine model are technically demanding and do not lead to permanent anchoring on the fetus until the end of gestation.

Surg Endosc 2020 Feb 18. Epub 2020 Feb 18.

Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

Introduction: This is the cumulative technical report on the operative procedures and limitations of fetoscopic bag insertion, intestinal bag placement, and bag fixation to the fetus in a series of pilot studies in an ovine model for prenatal treatment of gastroschisis.

Material And Methods: In 24 German blackhead sheep, a surgically created gastroschisis was managed by fetoscopic placement of the extruded intestines into a bag. The bag was then fastened onto the fetal abdominal wall. Read More

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http://dx.doi.org/10.1007/s00464-020-07441-7DOI Listing
February 2020
3.256 Impact Factor

Sex differences in surgically correctable congenital anomalies: A systematic review.

J Pediatr Surg 2020 May 12;55(5):811-820. Epub 2020 Feb 12.

Division of Pediatric Surgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada. Electronic address:

Purpose: This study aims to compare the prevalence and outcomes of surgically correctable congenital anomalies between sexes.

Methods: Upon registration on PROSPERO (CRD42019120165), a librarian aided in conducting a systematic review using PRISMA guidelines. The five largest relevant studies were included for each anomaly. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.01.016DOI Listing

Lifestyle and sociodemographic risk factors for gastroschisis: a systematic review and meta-analysis.

Arch Dis Child 2020 Feb 12. Epub 2020 Feb 12.

Institute of Clinical Physiology National Research Council, Pisa, Italy.

Background: Gastroschisis is strongly associated with young maternal age. This association suggests the need for further investigations on non-genetic risk factors. Identifying these risk factors is a public health priority in order to develop prevention strategies aimed at reducing the prevalence and health consequences in offspring. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318412DOI Listing
February 2020

Pregnancy outcomes of women with elevated second-trimester maternal serum alpha-fetoprotein.

Taiwan J Obstet Gynecol 2020 Jan;59(1):73-78

Medical School, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China; National Health Commission's Key Laboratory for Healthy Births in Western China, Department of Obstetrics and Gynecology, First People's Hospital of Yunnan Province, Kunming 650032, Yunnan, PR China. Electronic address:

Objective: The aim of this study was to investigate the overall distribution of pregnancy outcomes in women with elevated second-trimester maternal serum alpha-fetoprotein (MS-AFP), and to determine the risk of adverse pregnancy outcomes (APOs) by MS-AFP level.

Materials And Methods: We retrospectively analyzed the clinical data of 429 women with elevated MS-AFP (≥2.5 multiple of the median (MOM)) and 1555 women with normal MS-AFP (0. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.11.011DOI Listing
January 2020

[Autologous reconstructive surgery and intestinal rehabilitation in the management of short bowel syndrome].

Orv Hetil 2020 Feb;161(7):243-251

Sebészeti Műtéttani Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.

Based on the latest definition, short bowel syndrome is defined as intestinal failure due to the loss of significant small bowel length or function, when the homeostasis and growth can only be maintained with intravenous supplementation of fluid, electrolytes and macronutrients. The natural adaptation of the short bowel can only compensate for the loss up to a certain level. According to this, we differentiate (1) acute, (2) prolonged and (3) chronic types of intestinal failure/short bowel syndrome. Read More

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http://dx.doi.org/10.1556/650.2020.31655DOI Listing
February 2020

Presence of congenital anomalies in three dog litters.

Reprod Domest Anim 2020 May 17;55(5):652-655. Epub 2020 Feb 17.

Department of Animal Health and Preventive Medicine, Faculty of Veterinary Medicine and Animal Science, Autonomous University of Yucatan, Merida, Mexico.

This report describes multiple congenital malformations found in three dog litters delivered by emergency caesarean section. In all of the litters, some puppies were born alive but were euthanized because of the seriousness of their malformations and low probability of survival. In two litters, gastroschisis was associated with amelia of the right anterior limb. Read More

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http://dx.doi.org/10.1111/rda.13652DOI Listing

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children's Study.

BMC Res Notes 2020 Jan 30;13(1):47. Epub 2020 Jan 30.

Centre for Health and Environmental Risk Research, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan.

Objective: For several observational studies that have reported the factors related to gastroschisis, the target population in these studies was mainly residents of Europe or the US, and there is little data on the Asian population. In this study, we summarised characteristics of Japanese women who delivered infants with gastroschisis, particularly focusing on the pre-pregnancy body mass index (BMI), which was found to be inversely associated with gastroschisis in past studies, because the distribution of BMI is clearly different in Asia and the West.

Results: We used data from a nationwide birth cohort study which recruited pregnant women between 2011 and 2014. Read More

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http://dx.doi.org/10.1186/s13104-020-4915-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990474PMC
January 2020

A systematic scoping review of clinical indications for induction of labour.

PLoS One 2020 29;15(1):e0228196. Epub 2020 Jan 29.

Centre for Midwifery and Child and Family Health, Faculty of Health, University of Technology Sydney, Australia.

Background: The proportion of women undergoing induction of labour (IOL) has risen in recent decades, with significant variation within countries and between hospitals. The aim of this study was to review research supporting indications for IOL and determine which indications are supported by evidence and where knowledge gaps exist.

Methods: A systematic scoping review of quantitative studies of common indications for IOL. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228196PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988952PMC

Mother's own milk dose is associated with decreased time from initiation of feedings to discharge and length of stay in infants with gastroschisis.

J Perinatol 2020 Jan 28. Epub 2020 Jan 28.

Section of Neonatology, Department of Pediatrics, Rush University Medical Center, Chicago, IL, 60612, USA.

Objective: To determine if mother's own milk (MOM) dose after gastroschisis repair is associated with time from feeding initiation to discharge. Secondary outcomes included parenteral nutrition (PN) duration and length of stay (LOS).

Study Design: Retrospective study of 44 infants with gastroschisis examined demographics, gastroschisis type, PN days, timing of nutrition milestones, feeding composition, and LOS. Read More

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http://dx.doi.org/10.1038/s41372-020-0595-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223788PMC
January 2020

Vanishing Gastroschisis with a Favorable Outcome after a 3-Year Follow-Up: A Case Report and Literature Review.

Case Rep Obstet Gynecol 2020 7;2020:8542087. Epub 2020 Jan 7.

Department of Pediatric Surgery, Hautepierre, University Hospital, Strasbourg, France.

Vanishing gastroschisis (VG) is a severe complication of gastroschisis with a high mortality rate. We report here a case of VG with a favorable outcome after a 3-year follow-up. A 26-year-old primigravida woman was referred to Strasbourg University Hospital because her fetus was diagnosed with an isolated gastroschisis at 13-week gestation. Read More

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http://dx.doi.org/10.1155/2020/8542087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969982PMC
January 2020

Reducing Gastroschisis Mortality: A Quality Improvement Initiative at a Ugandan Pediatric Surgery Unit.

World J Surg 2020 May;44(5):1395-1399

Department of Paediatric Surgery, Childrens Hospital Level 2, University of Oxford and Oxford University Hospitals, John Radcliffe Site, Headley way, Oxford, OX3 9DA, UK.

Introduction: With modern treatment, survival of gastroschisis exceeds 90% in high-income countries. Survival in these countries has been largely attributed to prenatal diagnosis, delivery at tertiary facilities with timely resuscitation, timely intervention, parenteral nutrition and intensive care facilities. In sub-Saharan Africa, due to lack of these facilities, mortality rates are still alarmingly high ranging from 75 to 100%. Read More

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http://dx.doi.org/10.1007/s00268-020-05373-wDOI Listing