2,387 results match your criteria Gastroschisis


Developing and implementing an interventional bundle to reduce mortality from gastroschisis in low-resource settings.

Wellcome Open Res 2019 8;4:46. Epub 2019 Mar 8.

King's Centre for Global Health and Health Partnerships, School of Population Health and Environmental Sciences, King's College London, London, SE5 9RJ, UK.

Gastroschisis is associated with less than 4% mortality in high-income countries and over 90% mortality in many tertiary paediatric surgery centres across sub-Saharan Africa (SSA). The aim of this trial is to develop, implement and prospectively evaluate an interventional bundle to reduce mortality from gastroschisis in seven tertiary paediatric surgery centres across SSA. A hybrid type-2 effectiveness-implementation, pre-post study design will be utilised. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/wellcomeopenres.15113.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456836PMC
March 2019
2 Reads

Impact of maternal education on the outcome of newborns requiring surgery for congenital malformations.

PLoS One 2019 8;14(4):e0214967. Epub 2019 Apr 8.

Department of Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Objective: Numerous studies established a link between socioeconomic status (SES) and several dimensions of general health. This study examines the association between maternal education as a widely used indicator of SES and outcome in newborns requiring surgical correction of congenital anomalies.

Methods: Ambispective data analysis of newborns with esophageal atresia (EA), intestinal atresia (IA), congenital diaphragmatic hernia (CDH), omphalocele (OC), gastroschisis (GS) undergoing surgery between 01/2008-11/2017 accessing the clinical databases Neodat and Viewpoint. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214967PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453467PMC
April 2019
2 Reads

Gastroschisis may be good, bad, not so ugly, and falsely beautiful.

J Pediatr Surg 2019 Mar 25. Epub 2019 Mar 25.

Disciplines of Pediatric Surgery and Pathology, Antonio Pedro University Hospital, Federal Fluminense University, Rio de Janeiro, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2019.02.059DOI Listing
March 2019
3 Reads

Author response to "Gastroschisis may be good, bad, not so ugly and falsely beautiful".

J Pediatr Surg 2019 Mar 25. Epub 2019 Mar 25.

Rady Children's Hospital, 3030 Children's Way, MC 5136, San Diego, CA 92123. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2019.03.011DOI Listing

Development of venous thrombi in a pediatric population of intestinal failure.

J Pediatr Surg 2019 Mar 7. Epub 2019 Mar 7.

Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham. Electronic address:

Background/purpose: Although pediatric intestinal failure (IF) is now a survivable diagnosis, children are still at risk for complications. Loss of venous access persists as a leading indication for intestinal transplantation. The goal of this study was to identify risk factors for loss of venous access in a pediatric intestinal failure population on long-term PN. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00223468183088
Publisher Site
http://dx.doi.org/10.1016/j.jpedsurg.2018.12.022DOI Listing
March 2019
4 Reads

Risk factors for abdominal wall defects.

Congenit Anom (Kyoto) 2019 Apr 1. Epub 2019 Apr 1.

Department of Surgery (Paediatric Surgery Section), University of Ulm, Ulm, Germany.

In the last decades, the prevalence of gastroschisis (GS) has increased worldwide. The purpose of this study was to identify maternal risk factors explaining the described gain and to identify differences between GS and omphalocele (OC). A case-control design was used to compare GS (n = 36) and OC (n = 18) mothers to control group (CG; n = 30) matched for maternal age. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cga.12336DOI Listing
April 2019
6 Reads

Risk of gastroschisis with maternal genitourinary infections: the US National birth defects prevention study 1997-2011.

BMJ Open 2019 Mar 30;9(3):e026297. Epub 2019 Mar 30.

Division of Medical Genetics, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA.

Objective: To assess the association between occurrence and timing of maternal self-reported genitourinary tract infection (urinary tract infections [UTIs] and/or sexually transmitted infection [STI]) and risk for gastroschisis in the offspring.

Design: Population-based case-control study.

Setting: National Birth Defects Prevention Study, a multisite study in the USA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-026297DOI Listing
March 2019
3 Reads

Gastroschisis as a thrombotic disruption.

Authors:
Mark Lubinsky

Birth Defects Res 2019 Mar 29. Epub 2019 Mar 29.

Wauwatosa, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdr2.1503DOI Listing

Prevalence of selected birth defects by maternal nativity status, United States, 1999-2007.

Birth Defects Res 2019 Mar 28. Epub 2019 Mar 28.

Birth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, Texas.

Objectives: We investigated differences in prevalence of major birth defects by maternal nativity within racial/ethnic groups for 27 major birth defects.

Methods: Data from 11 population-based birth defects surveillance systems in the United States including almost 13 million live births (approximately a third of U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdr2.1489DOI Listing
March 2019
1 Read

A 25-year study of gastroschisis outcomes in a middle-income country.

J Pediatr Surg 2019 Feb 24. Epub 2019 Feb 24.

Department of Surgery, School of Medicine, Universidade Federal de Minas Gerais; Pediatric Surgical Service, Hospital das Clínicas of the Universidade Federal de Minas Gerais/Empresa, Brasileira, de Serviços Hospitalares. Belo Horizonte, Minas Gerais, Brazil.

Background: Survival of newborns with gastroschisis is significantly higher in high-income versus low and middle-income countries. We reviewed treatment and outcomes of gastroschisis in a middle-income country setting with increasing protocolized management.

Methods: All newborns with gastroschisis treated during the period 1989-2013 at a single Brazilian academic surgical service were studied retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2019.02.020DOI Listing
February 2019
6 Reads

Gestational Outcomes of Pregnancies with Prenatally Detected Gastroschisis and Omphalocele.

Fetal Pediatr Pathol 2019 Mar 20:1-8. Epub 2019 Mar 20.

a Division of Perinatology, Department of Obstetrics and Gynecology , Hacettepe University Hospital , Ankara , Turkey.

Objective: To evaluate and compare the outcomes of pregnancies with prenatally detected gastroschisis and omphalocele.

Materials And Methods: We retrospectively evaluated prenatally detected gastroschisis and omphalocele cases. Cases were compared in terms of maternal demographic and clinical characteristics as well as pregnancy and neonatal outcomes. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/15513815.2019.1
Publisher Site
http://dx.doi.org/10.1080/15513815.2019.1585501DOI Listing
March 2019
4 Reads

Anterior abdominal wall defects managed at a tertiary maternal-fetal medicine service in New Zealand: What counselling advice can we offer parents?

Aust N Z J Obstet Gynaecol 2019 Mar 6. Epub 2019 Mar 6.

Maternal Fetal Medicine, School of Medicine, University of Auckland, Auckland, New Zealand.

Background: Anterior abdominal wall defects, including gastroschisis and omphalocoele, are common fetal anomalies. The management remains complicated, and their diagnosis may lead to significant parental distress. Effective parental counselling may impact on parental perceptions of the defect and help guide pregnancy management. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajo.12965
Publisher Site
http://dx.doi.org/10.1111/ajo.12965DOI Listing
March 2019
12 Reads

Long-term outcomes of ultrashort bowel syndrome due to malrotation with midgut volvulus managed at an interdisciplinary pediatric intestinal rehabilitation center.

J Pediatr Surg 2019 Feb 2. Epub 2019 Feb 2.

Center for Advanced Intestinal Rehabilitation, Department of Surgery; Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

Purpose: The purpose of this study was to describe long-term outcomes of pediatric-onset ultrashort bowel syndrome owing to midgut volvulus managed at an interdisciplinary intestinal rehabilitation center.

Methods: Patients with a history of malrotation and pediatric-onset midgut volvulus causing extensive bowel loss (<20% residual small bowel length expected for postconception age) and treated between 2010 and 2017 were reviewed. Data are expressed as median (IQR). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2019.01.025DOI Listing
February 2019
2 Reads

An evolutionary and developmental biology approach to gastroschisis.

Birth Defects Res 2019 Apr 28;111(6):294-311. Epub 2019 Feb 28.

Division of Medical Genetics, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.

Recent advances have now made it possible to speak of gastroschisis narrowly in morphogenetic terms invoking the Rittler-Beaudoin (R-B) model. This proceeds from the appreciation of gastroschisis as a congenital intestinal herniation (without cover or liver) within the primordial umbilical ring, mostly to the right side of a normally formed umbilical cord. Presently, it is unresolved whether this visceral prolapse represents failure of ring closure before return of the physiological hernia into the abdomen or rupture of the delicate amniotic/peritoneal membrane at the ring's edge to the right of the cord. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdr2.1481DOI Listing
April 2019
1 Read

The evolution of the serial transverse enteroplasty for pediatric short bowel syndrome at a single institution.

J Pediatr Surg 2019 Feb 5. Epub 2019 Feb 5.

The Group for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CANADA; Division of General and Thoracic Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CANADA; Transplant and Regenerative Medicine Center, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CANADA. Electronic address:

Purpose: The serial transverse enteroplasty (STEP) tapers and lengthens the gut to improve adaptation. Mortality has decreased with multidisciplinary intestinal rehabilitation programs (IRP) allowing more time to reach adaptive potential. We reviewed our STEP experience to compare surgical outcomes between early and late eras of our IRP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2019.01.051DOI Listing
February 2019
2 Reads

Influence of periconception smoking behavior on birth defect risk.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Electronic address:

Background: Smoking is one of the most important modifiable risk factors for adverse maternal and neonatal outcomes. Smoking during pregnancy has been associated with fetal growth restriction, adverse pregnancy outcomes, and chronic adult diseases. Existing research has evaluated the risk of smoking on congenital defects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2019.02.029DOI Listing
February 2019
2 Reads

Giant Gastroschisis with Complete Liver Herniation: A Case Report of Two Patients.

Case Rep Surg 2019 15;2019:4136214. Epub 2019 Jan 15.

Department of General Surgery, Boston Children's Hospital, 300 Longwood Ave, Fegan 3, Boston MA 20115, USA.

Introduction: There are no reported survivors of gastroschisis with complete liver herniation. We describe a case report of two patients, one of whom survived.

Case #1: The patient was born with gastroschisis and herniation of the entire liver. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/4136214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350565PMC
January 2019
1 Read

Neonatal Intestinal Anastomosis Using a 5 mm Laparoscopic Stapler.

J Laparoendosc Adv Surg Tech A 2019 Apr 15;29(4):579-581. Epub 2019 Feb 15.

1 Department of Surgery, Wright State University, Miami Valley Hospital Weber Center for Health Education, Dayton, Ohio.

Recently, a 5 mm laparoscopic stapler entered the market and is currently used for a wide variety of pediatric applications. The aim of this article is to be the first report of the use of this 5 mm laparoscopic stapler for open neonatal intestinal anastomosis in humans. We used JustRight (Justright Surgical) 5 mm laparoscopic stapler in 5 patients, with a total of six anastomoses being constructed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/lap.2018.0524DOI Listing
April 2019
2 Reads

Gastroschisis and Autism-Dual Canaries in the Californian Coalmine-Reply.

JAMA Surg 2019 Feb 6. Epub 2019 Feb 6.

UC Davis Medical Center, University of California, Sacramento.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamasurg.2018.4697DOI Listing
February 2019
1 Read

Gastroschisis and Autism-Dual Canaries in the Californian Coalmine.

JAMA Surg 2019 Feb 6. Epub 2019 Feb 6.

School of Health and Medical Sciences, Edith Cowan University, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
Publisher Site
http://dx.doi.org/10.1001/jamasurg.2018.4694DOI Listing
February 2019
7 Reads

Re: Gastroschisis and Cumulative Stressor Exposures.

Authors:
Mark Lubinsky

Epidemiology 2019 03;30(2):e11-e12

Wauwatosa, WI,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/EDE.0000000000000967DOI Listing
March 2019
1 Read

Low and decreased prevalence of congenital abdominal wall defect in Taiwan.

J Pediatr Surg 2018 Dec 28. Epub 2018 Dec 28.

Department of General Surgery, Buddhist Dalin Tzu Chi Hospital, Chia-Yi, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan. Electronic address:

Purpose: This study aims to identify the prevalence of Congenital abdominal wall defects (AWD), hospital outcomes, and related congenital abnormalities in Taiwan by using the National Health Insurance Research Database (NHIRD).

Materials And Methods: From 1998 through 2013, all pediatric patients with AWD were collected via ICD-9-CM diagnostic code 756.7x ("congenital anomalies of abdominal wall") or procedure codes (54. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00223468183078
Publisher Site
http://dx.doi.org/10.1016/j.jpedsurg.2018.11.011DOI Listing
December 2018
12 Reads

Sutureless closure: a versatile treatment for the diverse presentations of gastroschisis.

J Perinatol 2019 Jan 28. Epub 2019 Jan 28.

Division of Pediatric Surgery, University of Virginia, Charlottesville, VA, USA.

Objective: Case series have demonstrated sutureless closures to be safe for the correction of gastroschisis. We hypothesize that sutureless closure is efficacious in patients requiring silo reduction without need for intubation.

Study Design: We conducted a retrospective case control study of infants who underwent gastroschisis repair at our institution (January 2011-August 2018). Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41372-019-0321-1
Publisher Site
http://dx.doi.org/10.1038/s41372-019-0321-1DOI Listing
January 2019
6 Reads

Improving outcomes for neonates with gastroschisis in low-income and middle-income countries: a systematic review protocol.

BMJ Paediatr Open 2018 27;2(1):e000392. Epub 2018 Dec 27.

King's Centre for Global Health and Health Partnerships, School of Population Health and Environmental Sciences, King's College London, London, UK.

Introduction: There is a significant disparity in outcomes for neonates with gastroschisis in high-income countries (HICs) compared with low-income and middle-income countries (LMICs). Many LMICs report mortality rates between 75% and 100% compared with <4% in HICs.

Aim: To undertake a systematic review identifying postnatal interventions associated with improved outcomes for gastroschisis in LMICs. Read More

View Article

Download full-text PDF

Source
http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
Publisher Site
http://dx.doi.org/10.1136/bmjpo-2018-000392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326322PMC
December 2018
5 Reads

Nutrition for the Surgical Infant with Gastroschisis.

Neonatal Netw 2019 Jan;38(1):17-26

Nutrition for the infant with gastroschisis is a complex topic and there is not a lot of uniformity in the literature to formulate evidence-based care. This article discusses more recent findings in the literature as we search for an effective method of feeding these infants. Issues with growth and development, illustrating the variety of outcomes, are also addressed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1891/0730-0832.38.1.17DOI Listing
January 2019

Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates - United States, 2006-2015.

MMWR Morb Mortal Wkly Rep 2019 Jan 18;68(2):31-36. Epub 2019 Jan 18.

Prevalence of gastroschisis, a serious birth defect of the abdominal wall resulting in some of the abdominal contents extending outside the body at birth, has been increasing worldwide (1,2). Gastroschisis requires surgical repair after birth and is associated with digestive and feeding complications during infancy, which can affect development. Recent data from 14 U. Read More

View Article

Download full-text PDF

Source
http://www.cdc.gov/mmwr/volumes/68/wr/mm6802a2.htm?s_cid=mm6
Publisher Site
http://dx.doi.org/10.15585/mmwr.mm6802a2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336188PMC
January 2019
15 Reads

The intestinal fatty acid-binding protein as a marker for intestinal damage in gastroschisis.

PLoS One 2019 14;14(1):e0210797. Epub 2019 Jan 14.

Department of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Background/purpose: We analyzed the capacity of urinary Intestinal fatty acid-binding protein (I-FABP) to quantify the degree of mucosal injury in neonates with gastroschisis (GS) and to predict the speed of their clinical recovery after surgery.

Methods: In this prospective study, we collected urine during the first 48h after surgery from neonates operated between 2012 and 2015 for GS. Neonates with surgery that did not include gut mucosa served as controls for simple GS and neonates with surgery for intestinal atresia served as control for complex GS patients. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210797PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331122PMC
January 2019
1 Read

Serial Reduction of an Extremely Large Gastroschisis using Vacuum-Assisted Closure.

European J Pediatr Surg Rep 2018 Jan 26;6(1):e97-e99. Epub 2018 Dec 26.

Division of Pediatric Surgery, Department of Surgery, Stanford University, Stanford, California, United States.

We herein describe a case of serial reduction of an extremely large and complex gastroschisis using vacuum-assisted closure (VAC) therapy in a boy born at 35 weeks' gestation. A spring-loaded silicone silo was placed at birth. By day of life (DOL) 22, minimal visceral contents had been reduced, and the silo was difficult to maintain due to the size of the fascial defect and loss of abdominal domain. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0038-1676045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306277PMC
January 2018
3 Reads

A machine learning approach to investigate potential risk factors for gastroschisis in California.

Birth Defects Res 2019 Mar 26;111(4):212-221. Epub 2018 Dec 26.

Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California.

Background: To generate new leads about risk factors for gastroschisis, a birth defect that has been increasing in prevalence over time, we performed an untargeted data mining statistical approach.

Methods: Using data exclusively from the California Center of the National Birth Defects Prevention Study, we compared 286 cases of gastroschisis and 1,263 non-malformed, live-born controls. All infants had delivery dates between October 1997 and December 2011 and were stratified by maternal age at birth (<20 and ≥ 20 years). Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/bdr2.1441
Publisher Site
http://dx.doi.org/10.1002/bdr2.1441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397054PMC
March 2019
10 Reads

The feasibility of routine use of distal stoma refeeding method in newborns with enterostomy.

J Matern Fetal Neonatal Med 2018 12 25:1-101. Epub 2018 Dec 25.

a Department of Pediatric Surgery , Medical University of Innsbruck , Innsbruck , Austria.

Objective: Temporary enterostomies are life-saving in neonatal surgery, however causing loss of fluid electrolyte, delays in distal bowel adaptation and thus delayed growth of newborns. In this study, we aimed to present the method and clinical results of distal stoma refeeding in premature and mature neonates.

Methods: Between January 2012 and December 2017, records of newborn patients who underwent enterostomy and distal stoma refeeding were retrospectively analysed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2018.1563593DOI Listing
December 2018
3 Reads

Probiotic research in neonates with congenital gastrointestinal surgical conditions - Now is the time.

Microb Biotechnol 2019 03 21;12(2):254-258. Epub 2018 Dec 21.

Centre for Neonatal Research and Education, University of Western Australia, Perth, WA, Australia.

Neonates with congenital gastrointestinal surgical conditions (CGISC) receive parenteral nutrition, get exposed to multiple courses of antibiotics, undergo invasive procedures, and are nursed in intensive care units. They do not receive early enteral feeding and have limited opportunities for skin to skin contact with their mothers. Many of these infants receive gastric acid suppression therapies. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/1751-7915.13358
Publisher Site
http://dx.doi.org/10.1111/1751-7915.13358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389852PMC
March 2019
5 Reads

An unusual association of left-sided gastroschisis and persistent right umbilical vein.

Clin Case Rep 2018 Dec 5;6(12):2511-2512. Epub 2018 Nov 5.

Neonatal Intensive Care Unit, A.U.O.P. "P. Giaccone", Department of Sciences for Health Promotion and Mother and Child Care "G. D'Alessandro" University of Palermo Palermo Italy.

Gastroschisis is a full-thickness congenital abdominal wall defect usually occurring to the right of the umbilicus. About twenty cases of left-sided gastroschisis have been reported, without reference to the laterality of the umbilical vein. This first case highlights the importance of considering and reporting this association by the perinatal team. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccr3.1897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293187PMC
December 2018
1 Read

High risk of spontaneous preterm birth among infants with gastroschisis.

Am J Med Genet A 2019 Jan 14;179(1):37-42. Epub 2018 Dec 14.

California Preterm Birth Initiative, University of California San Francisco, San Francisco, California.

We examined the association between gastroschisis and preterm birth (PTB, <37 weeks) by subtype. The sample was drawn from singleton live births in California from 2007 to 2012 contained in a birth cohort file maintained by the California Office of Statewide Health Planning and Development (n = 2,891,965; 1,421 with gastroschisis). Relative risks (RRs) and 95% confidence intervals (CIs) were calculated for PTB by gestational age (<34, 34-36, and any <37 weeks) and by type (spontaneous labor with intact membranes, preterm premature rupture of the membranes [PPROM], provider initiated) and were adjusted for maternal characteristics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.60675DOI Listing
January 2019
3 Reads

Non-transplant surgical management of short bowel syndrome in children: an overview.

Curr Pediatr Rev 2018 Nov 29. Epub 2018 Nov 29.

University of Florence, Meyer Children's Hospital, Florence. Italy.

Management of severe Short Bowel Syndrome (SBS) is still one of the largest challenges of the medicine. Vast majority of the short bowel patients are children, the conditions that lead to this possible outcome most often are necrotizing enterocolitis (NEC), small intestinal volvulus as a result of intestinal malrotation, gastroschisis and the "apple peel" syndrome. Therefore paediatricians and paediatric surgeons face this challenge most often. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666181129164112DOI Listing
November 2018
14 Reads

Closing gastroschisis: The good, the bad, and the not-so ugly.

J Pediatr Surg 2019 Jan 5;54(1):60-64. Epub 2018 Oct 5.

Rady Children's Hospital, San Diego, CA. Electronic address:

Purpose: The diagnosis of "closing" or "closed gastroschisis" is made when bowel is incarcerated within a closed or nearly closed ring of fascia, usually with associated bowel atresia. It has been described as having a high morbidity and mortality.

Methods: A retrospective review of closing gastroschisis cases (n = 53) at six children's hospitals between 2000 and 2016 was completed after IRB approval. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00223468183065
Publisher Site
http://dx.doi.org/10.1016/j.jpedsurg.2018.10.033DOI Listing
January 2019
4 Reads

Prevalence and predictors of mortality in gastroschisis: a population-based study of 4803 cases in the USA.

J Matern Fetal Neonatal Med 2018 Nov 26:1-7. Epub 2018 Nov 26.

a Department of Obstetrics and Gynecology , Jewish General Hospital, McGill University , Montreal , QC , Canada.

Purpose: Gastroschisis is a rare congenital anomaly consisting of an abdominal wall defect resulting in extrusion of the abnormal organs. Survival of these infants exceeds 90%. Few large-scale studies have examined the predictors of mortality for these infants. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14767058.2018.1
Publisher Site
http://dx.doi.org/10.1080/14767058.2018.1529163DOI Listing
November 2018
6 Reads

Meconium aspiration syndrome requiring ECMO in newborns with gastroschisis: incidence and surgical outcomes.

Pediatr Surg Int 2019 Apr 16;35(4):469-472. Epub 2018 Nov 16.

Division of General, Thoracic and Fetal Surgery, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Wood Building-Suite 5100, Philadelphia, PA, USA.

Aim Of The Study: To evaluate the incidence of respiratory failure requiring ECMO in newborns with gastroschisis (GC), compare it to the incidence in the general population, review the surgical outcomes of newborns with GC requiring ECMO and compare them to newborns with GC not requiring ECMO.

Methods: This is a retrospective review of all neonatal admissions for GC from December 2010 to September 2015.

Main Results: 110 newborns with GC were admitted to our NICU between 12/2010 and 9/2015; 36 were term. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00383-018-4419-xDOI Listing
April 2019
4 Reads

Meconium exposure in gastroschisis.

J Pediatr Surg 2019 Feb 23;54(2):365. Epub 2018 Oct 23.

Neonatal-Perinatal Medicine, Associate Director PremieR Clinic, Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Oklahoma Health Sciences Center, 1200 Everett Drive, ETNP 7504, 7th Floor North Pavilion, Oklahoma City, OK 73104.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2018.10.055DOI Listing
February 2019
3 Reads

Direct hyperbilirubinemia in newborns with gastroschisis.

Pediatr Surg Int 2019 Mar 10;35(3):293-301. Epub 2018 Nov 10.

Department of Pediatric Surgery, John R. Oishei Children's Hospital, 1001 Main Street, Buffalo, NY, 14203, USA.

Background: Patients with gastroschisis and prolonged total (or partial) parenteral nutrition (PN) commonly develop direct hyperbilirubinemia (DH).

Objective: To quantify the prevalence and severity of DH in newborns with gastroschisis and characterize the diagnostic work-up for DH in this patient population.

Design/methods: Retrospective chart review of patients born with gastroschisis between 2005 and 2015 for the first 6 months of life. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00383-018-4415-1
Publisher Site
http://dx.doi.org/10.1007/s00383-018-4415-1DOI Listing
March 2019
21 Reads

Medium and long-term outcomes of gastroschisis.

Semin Pediatr Surg 2018 Oct 6;27(5):327-329. Epub 2018 Sep 6.

Department of Paediatric Surgery, Children's Hospital, University of Helsinki, P.O. Box 281, Helsinki FIN-00029 HUS, Finland. Electronic address:

As survival of gastroschisis patients has improved significantly, it has become apparent that longitudinal follow up strategies need to be developed. Problems concerning patients with gastroschisis are usually associated with gastrointestinal morbidity, but there is mounting evidence that also neurodevelopmental, cognitive, behavioral and late-onset auditory sequelae exist. The presence of associated anomalies, as well as complex features (bowel atresia, necrosis, volvulus, perforation) increase morbidity and impact long-term outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.008DOI Listing
October 2018
5 Reads

Care of infants with gastroschisis in low-resource settings.

Semin Pediatr Surg 2018 Oct 5;27(5):321-326. Epub 2018 Sep 5.

Paediatric Surgery Department, King's College Hospital, Denmark Hill, London SE5 9RS, United Kingdom. Electronic address:

There is great global disparity in the outcome of infants born with gastroschisis. Mortality approaches 100% in many low income countries. Barriers to better outcomes include lack of antenatal diagnosis, deficient pre-hospital care, ineffective neonatal resuscitation and venous access, limited intensive care facilities, poor access to the operating theatre and safe neonatal anesthesia, and lack of neonatal parenteral nutrition. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10558586183006
Publisher Site
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.004DOI Listing
October 2018
11 Reads

Impact of societal factors and health care delivery systems on gastroschisis outcomes.

Semin Pediatr Surg 2018 Oct 28;27(5):316-320. Epub 2018 Aug 28.

Department of Surgery, Division of Pediatric Surgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, 300 Pasteur Drive, Alway Building M116, Stanford, CA 94305, USA. Electronic address:

Care of infants with gastroschisis is associated with a significant burden on health care delivery systems. Mortality rates in patients with gastroschisis have significantly improved over the past few decades. However, the condition is still associated with significant short-term and potentially long-term morbidity. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10558586183007
Publisher Site
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.010DOI Listing
October 2018
10 Reads

Surgical strategies in complex gastroschisis.

Authors:
Sherif Emil

Semin Pediatr Surg 2018 Oct 25;27(5):309-315. Epub 2018 Aug 25.

Department of Pediatric Surgery; The Montreal Children's Hospital, McGill University Health Centre, Room B04.2028, 1001 Decarie Boulevard, Montreal, QC, Canada H4A 3J1. Electronic address:

Currently, the most important determinant of gastroschisis outcomes in high resource settings is whether the condition is associated with intestinal complications, such as atresia, necrosis, perforation, or volvulus. This form of the anomaly, known as complex gastroschisis, accounts for most of the mortality and a disproportionate burden of the morbidity from gastroschisis. There is some disagreement about what constitutes complex gastroschisis, and little consensus on the type and timing of surgical interventions. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10558586183006
Publisher Site
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.003DOI Listing
October 2018
15 Reads

Closure methods in gastroschisis.

Semin Pediatr Surg 2018 Oct 28;27(5):304-308. Epub 2018 Aug 28.

Children's National Health System, George Washington University Medical Center, United States. Electronic address:

The expected outcome of gastroschisis has evolved from an almost certain death of the child prior to the use of parenteral nutrition to almost certain survival. The primary goal of the surgical intervention is return of eviscerated contents into the abdominal cavity. The optimal surgical technique is dependent on the status of the intestine and the accommodation of abdominal domain. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.009DOI Listing
October 2018
2 Reads

Risk stratification and outcome determinants in gastroschisis.

Semin Pediatr Surg 2018 Oct 3;27(5):300-303. Epub 2018 Sep 3.

Division of Pediatric General and Thoracic Surgery, The Montreal Children's Hospital, McGill University Health Centre, Room B04.2318, 1001 Decarie Boulevard, Montreal, Quebec, Canada. Electronic address:

Selection of outcome determinants and risk stratification are necessary to identify patients at higher risk for morbidity and mortality. This facilitates human and material resource allocation and allows for improved family counseling. While several different factors, including prenatal ultrasonographic bowel features, the timing and mode of delivery, and the features of bowel injury have been investigated in gastroschisis, there is still significant debate as to which of these best predicts outcome. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10558586183006
Publisher Site
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.007DOI Listing
October 2018
24 Reads

Advances in prenatal and perinatal diagnosis and management of gastroschisis.

Semin Pediatr Surg 2018 Oct 5;27(5):289-299. Epub 2018 Sep 5.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of California Irvine Medical Center, Orange, CA, USA. Electronic address:

Gastroschisis is a congenital, ventral wall defect associated with bowel evisceration. The defect is usually to the right of the umbilical cord insertion and requires postnatal surgical correction. The fetus is at risk for complications such as intrauterine growth restriction, preterm delivery, and intrauterine fetal demise. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10558586183006
Publisher Site
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.006DOI Listing
October 2018
14 Reads

Insights into the etiology and embryology of gastroschisis.

Authors:
Sylvie Beaudoin

Semin Pediatr Surg 2018 Oct 27;27(5):283-288. Epub 2018 Aug 27.

Service de Chirurgie Pédiatrique, Hôpital Universitaire Necker Enfants Malades, APHP, Paris, France; Département d'Anatomie et Morphogenèse, Université Paris Descartes, Paris, France. Electronic address:

The development of gastroschisis has long remained an area of interest and controversy. Successive theories about its pathogenesis are herein reviewed and discussed. Two historical assumptions, that omphalocele results from a persistent umbilical hernia, and that gastroschisis does not involve the umbilical cord, are dismissed. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10558586183006
Publisher Site
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.005DOI Listing
October 2018
15 Reads

Preface.

Authors:
Sherif Emil

Semin Pediatr Surg 2018 10 28;27(5):281-282. Epub 2018 Aug 28.

Department of Pediatric Surgery, The Montreal Children's Hospital, McGill University Health Centre, Room B04.2028 1001 Decarie Boulevard Montreal, QC H4A 3J1, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.sempedsurg.2018.08.002DOI Listing
October 2018
1 Read

Safety and usefulness of plastic closure in infants with gastroschisis: a systematic review and meta-analysis.

Pediatr Surg Int 2019 Jan 3;35(1):107-116. Epub 2018 Nov 3.

General and Thoracic Surgery, The Hospital for Sick Children, University of Toronto, 1526-555 University Ave, Toronto, ON, M5G 1X8, Canada.

Purpose: Recently, plastic closure of abdominal defect in infants with gastroschisis has been used. Timing of gastroschisis closure can be mainly divided into two groups: primary closure and delayed closure after silo forming. Safety and usefulness of plastic closure in gastroschisis remains unclear. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00383-018-4381-7
Publisher Site
http://dx.doi.org/10.1007/s00383-018-4381-7DOI Listing
January 2019
16 Reads

Re. Gastroschisis and cumulative stressor exposures.

Authors:
Mark Lubinsky

Epidemiology 2018 Oct 30. Epub 2018 Oct 30.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/EDE.0000000000000941DOI Listing
October 2018
1 Read