2,350 results match your criteria Gastroschisis


Non-transplant surgical management of short bowel syndrome in children: an overview.

Curr Pediatr Rev 2018 Nov 29. Epub 2018 Nov 29.

University of Florence, Meyer Children's Hospital, Florence. Italy.

Management of severe Short Bowel Syndrome (SBS) is still one of the largest challenges of the medicine. Vast majority of the short bowel patients are children, the conditions that lead to this possible outcome most often are necrotizing enterocolitis (NEC), small intestinal volvulus as a result of intestinal malrotation, gastroschisis and the "apple peel" syndrome. Therefore paediatricians and paediatric surgeons face this challenge most often. Read More

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November 2018
2 Reads

Closing gastroschisis: The good, the bad, and the not-so ugly.

J Pediatr Surg 2018 Oct 5. Epub 2018 Oct 5.

Rady Children's Hospital, San Diego, CA. Electronic address:

Purpose: The diagnosis of "closing" or "closed gastroschisis" is made when bowel is incarcerated within a closed or nearly closed ring of fascia, usually with associated bowel atresia. It has been described as having a high morbidity and mortality.

Methods: A retrospective review of closing gastroschisis cases (n = 53) at six children's hospitals between 2000 and 2016 was completed after IRB approval. Read More

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October 2018
1 Read

Prevalence and predictors of mortality in gastroschisis: a population-based study of 4803 cases in the USA.

J Matern Fetal Neonatal Med 2018 Nov 26:1-7. Epub 2018 Nov 26.

a Department of Obstetrics and Gynecology , Jewish General Hospital, McGill University , Montreal , QC , Canada.

Purpose: Gastroschisis is a rare congenital anomaly consisting of an abdominal wall defect resulting in extrusion of the abnormal organs. Survival of these infants exceeds 90%. Few large-scale studies have examined the predictors of mortality for these infants. Read More

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November 2018
5 Reads

Meconium aspiration syndrome requiring ECMO in newborns with gastroschisis: incidence and surgical outcomes.

Pediatr Surg Int 2018 Nov 16. Epub 2018 Nov 16.

Division of General, Thoracic and Fetal Surgery, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Wood Building-Suite 5100, Philadelphia, PA, USA.

Aim Of The Study: To evaluate the incidence of respiratory failure requiring ECMO in newborns with gastroschisis (GC), compare it to the incidence in the general population, review the surgical outcomes of newborns with GC requiring ECMO and compare them to newborns with GC not requiring ECMO.

Methods: This is a retrospective review of all neonatal admissions for GC from December 2010 to September 2015.

Main Results: 110 newborns with GC were admitted to our NICU between 12/2010 and 9/2015; 36 were term. Read More

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November 2018
1 Read

Meconium exposure in gastroschisis.

J Pediatr Surg 2018 Oct 23. Epub 2018 Oct 23.

Neonatal-Perinatal Medicine, Associate Director PremieR Clinic, Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Oklahoma Health Sciences Center, 1200 Everett Drive, ETNP 7504, 7th Floor North Pavilion, Oklahoma City, OK 73104.

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October 2018

Direct hyperbilirubinemia in newborns with gastroschisis.

Pediatr Surg Int 2018 Nov 10. Epub 2018 Nov 10.

Department of Pediatric Surgery, John R. Oishei Children's Hospital, 1001 Main Street, Buffalo, NY, 14203, USA.

Background: Patients with gastroschisis and prolonged total (or partial) parenteral nutrition (PN) commonly develop direct hyperbilirubinemia (DH).

Objective: To quantify the prevalence and severity of DH in newborns with gastroschisis and characterize the diagnostic work-up for DH in this patient population.

Design/methods: Retrospective chart review of patients born with gastroschisis between 2005 and 2015 for the first 6 months of life. Read More

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November 2018
5 Reads

Medium and long-term outcomes of gastroschisis.

Semin Pediatr Surg 2018 Oct 6;27(5):327-329. Epub 2018 Sep 6.

Department of Paediatric Surgery, Children's Hospital, University of Helsinki, P.O. Box 281, Helsinki FIN-00029 HUS, Finland. Electronic address:

As survival of gastroschisis patients has improved significantly, it has become apparent that longitudinal follow up strategies need to be developed. Problems concerning patients with gastroschisis are usually associated with gastrointestinal morbidity, but there is mounting evidence that also neurodevelopmental, cognitive, behavioral and late-onset auditory sequelae exist. The presence of associated anomalies, as well as complex features (bowel atresia, necrosis, volvulus, perforation) increase morbidity and impact long-term outcomes. Read More

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October 2018

Care of infants with gastroschisis in low-resource settings.

Semin Pediatr Surg 2018 Oct 5;27(5):321-326. Epub 2018 Sep 5.

Paediatric Surgery Department, King's College Hospital, Denmark Hill, London SE5 9RS, United Kingdom. Electronic address:

There is great global disparity in the outcome of infants born with gastroschisis. Mortality approaches 100% in many low income countries. Barriers to better outcomes include lack of antenatal diagnosis, deficient pre-hospital care, ineffective neonatal resuscitation and venous access, limited intensive care facilities, poor access to the operating theatre and safe neonatal anesthesia, and lack of neonatal parenteral nutrition. Read More

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October 2018
3 Reads

Impact of societal factors and health care delivery systems on gastroschisis outcomes.

Semin Pediatr Surg 2018 Oct 28;27(5):316-320. Epub 2018 Aug 28.

Department of Surgery, Division of Pediatric Surgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, 300 Pasteur Drive, Alway Building M116, Stanford, CA 94305, USA. Electronic address:

Care of infants with gastroschisis is associated with a significant burden on health care delivery systems. Mortality rates in patients with gastroschisis have significantly improved over the past few decades. However, the condition is still associated with significant short-term and potentially long-term morbidity. Read More

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October 2018
2 Reads

Surgical strategies in complex gastroschisis.

Authors:
Sherif Emil

Semin Pediatr Surg 2018 Oct 25;27(5):309-315. Epub 2018 Aug 25.

Department of Pediatric Surgery; The Montreal Children's Hospital, McGill University Health Centre, Room B04.2028, 1001 Decarie Boulevard, Montreal, QC, Canada H4A 3J1. Electronic address:

Currently, the most important determinant of gastroschisis outcomes in high resource settings is whether the condition is associated with intestinal complications, such as atresia, necrosis, perforation, or volvulus. This form of the anomaly, known as complex gastroschisis, accounts for most of the mortality and a disproportionate burden of the morbidity from gastroschisis. There is some disagreement about what constitutes complex gastroschisis, and little consensus on the type and timing of surgical interventions. Read More

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October 2018
2 Reads

Closure methods in gastroschisis.

Semin Pediatr Surg 2018 Oct 28;27(5):304-308. Epub 2018 Aug 28.

Children's National Health System, George Washington University Medical Center, United States. Electronic address:

The expected outcome of gastroschisis has evolved from an almost certain death of the child prior to the use of parenteral nutrition to almost certain survival. The primary goal of the surgical intervention is return of eviscerated contents into the abdominal cavity. The optimal surgical technique is dependent on the status of the intestine and the accommodation of abdominal domain. Read More

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October 2018
1 Read

Risk stratification and outcome determinants in gastroschisis.

Semin Pediatr Surg 2018 Oct 3;27(5):300-303. Epub 2018 Sep 3.

Division of Pediatric General and Thoracic Surgery, The Montreal Children's Hospital, McGill University Health Centre, Room B04.2318, 1001 Decarie Boulevard, Montreal, Quebec, Canada. Electronic address:

Selection of outcome determinants and risk stratification are necessary to identify patients at higher risk for morbidity and mortality. This facilitates human and material resource allocation and allows for improved family counseling. While several different factors, including prenatal ultrasonographic bowel features, the timing and mode of delivery, and the features of bowel injury have been investigated in gastroschisis, there is still significant debate as to which of these best predicts outcome. Read More

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October 2018
2 Reads

Advances in prenatal and perinatal diagnosis and management of gastroschisis.

Semin Pediatr Surg 2018 Oct 5;27(5):289-299. Epub 2018 Sep 5.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of California Irvine Medical Center, Orange, CA, USA. Electronic address:

Gastroschisis is a congenital, ventral wall defect associated with bowel evisceration. The defect is usually to the right of the umbilical cord insertion and requires postnatal surgical correction. The fetus is at risk for complications such as intrauterine growth restriction, preterm delivery, and intrauterine fetal demise. Read More

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October 2018
3 Reads

Insights into the etiology and embryology of gastroschisis.

Authors:
Sylvie Beaudoin

Semin Pediatr Surg 2018 Oct 27;27(5):283-288. Epub 2018 Aug 27.

Service de Chirurgie Pédiatrique, Hôpital Universitaire Necker Enfants Malades, APHP, Paris, France; Département d'Anatomie et Morphogenèse, Université Paris Descartes, Paris, France. Electronic address:

The development of gastroschisis has long remained an area of interest and controversy. Successive theories about its pathogenesis are herein reviewed and discussed. Two historical assumptions, that omphalocele results from a persistent umbilical hernia, and that gastroschisis does not involve the umbilical cord, are dismissed. Read More

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October 2018
5 Reads

Safety and usefulness of plastic closure in infants with gastroschisis: a systematic review and meta-analysis.

Pediatr Surg Int 2018 Nov 3. Epub 2018 Nov 3.

General and Thoracic Surgery, The Hospital for Sick Children, University of Toronto, 1526-555 University Ave, Toronto, ON, M5G 1X8, Canada.

Purpose: Recently, plastic closure of abdominal defect in infants with gastroschisis has been used. Timing of gastroschisis closure can be mainly divided into two groups: primary closure and delayed closure after silo forming. Safety and usefulness of plastic closure in gastroschisis remains unclear. Read More

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November 2018
3 Reads

Re. Gastroschisis and cumulative stressor exposures.

Authors:
Mark Lubinsky

Epidemiology 2018 Oct 30. Epub 2018 Oct 30.

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October 2018

Impact of disease-specific volume and hospital transfer on outcomes in gastroschisis.

J Pediatr Surg 2018 Oct 5. Epub 2018 Oct 5.

Center for Advanced Intestinal Rehabilitation, Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

Background: Gastroschisis, a surgical condition requiring complex interdisciplinary care, may benefit from treatment at higher volume centers. Recent studies on surgical volume and outcomes have conflicting findings.

Methods: Data were collected prospectively on newborns ≥1500 g with gastroschisis born 2009-2015, admitted to 159 US centers, and separated into terciles based on number of annual gastroschisis repairs. Read More

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October 2018
1 Read

Evaluation of Clinical Outcomes of Sutureless vs Sutured Closure Techniques in Gastroschisis Repair.

JAMA Surg 2018 Sep 19. Epub 2018 Sep 19.

Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco.

Importance: Sutureless gastroschisis repair offers an alternative to the traditional sutured method and has been associated with decreased intubation time. Published study results are inconsistent regarding the advantages of sutureless closure.

Objective: To compare the clinical outcomes of sutureless and sutured gastroschisis repair. Read More

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September 2018
2 Reads

A Gastroschisis bundle: effects of a quality improvement protocol on morbidity and mortality.

J Pediatr Surg 2018 Nov 19;53(11):2117-2122. Epub 2018 Jun 19.

Department of Pediatric Surgey, Hospital Infantil de México Federico Gomez, Mexico City, Mexico.

Objective: Gastroschisis incidence is rising. Survival in developed countries is over 95%. However, in underdeveloped countries, mortality is higher than 15% often due to sepsis. Read More

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November 2018
3 Reads

Re: Herpesvirus Infection in Infants with Gastroschisis.

Epidemiology 2019 Jan;30(1):e2

Department of Epidemiology, Boston University School of Public Health, Boston, MA,

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January 2019
1 Read

A safe and efficacious preventive strategy in the high-risk surgical neonate: cycled total parenteral nutrition.

Pediatr Surg Int 2018 Nov 28;34(11):1177-1181. Epub 2018 Sep 28.

Department of Surgery, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO, 64108, USA.

Introduction: Hepatic dysfunction in patients reliant on total parenteral nutrition (TPN) may benefit from cycled TPN. A concern for neonatal hypoglycemia has limited the use of cycled TPN in neonates less than 1 week of age. We sought to determine both the safety and efficacy of cycled TPN in surgical neonates less than 1 week of age. Read More

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November 2018

Epidemiology of gastroschisis: A population-based study in California from 1995 to 2012.

J Pediatr Surg 2018 Dec 4;53(12):2399-2403. Epub 2018 Sep 4.

Division of Pediatric General, Thoracic, and Fetal Surgery, University of California, Davis Medical Center, Sacramento, CA.

Background: Although the incidence of gastroschisis is increasing, risk factors are not clearly identified.

Methods: Using the Linked Birth Database from the California Office of Statewide Health Planning and Development from 1995 to 2012, patients with gastroschisis were identified by ICD-9 diagnosis/procedure code or birth certificate designation. Logistic regressions examined demographics, birth factors, and maternal exposures on risk of gastroschisis. Read More

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December 2018
1 Read

Association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis: A retrospective cohort analysis.

Acta Obstet Gynecol Scand 2018 Sep 28. Epub 2018 Sep 28.

Department of Obstetrics and Gynecology, Hospital das Clínicas, São Paulo University Medical School, Sao Paulo, Brazil.

Introduction: The present study aims to investigate the association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis. The secondary goal was to evaluate the association between ultrasound markers and labor onset in pregnancies with fetal gastroschisis.

Material And Methods: A retrospective analysis was performed for 207 pregnancies with fetal gastroschisis between 2005 and 2017. Read More

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September 2018
3 Reads

Single center protocol driven care in 150 patients with gastroschisis 1998-2017: collaboration improves results.

Pediatr Surg Int 2018 Nov 25;34(11):1171-1176. Epub 2018 Sep 25.

Department of Surgery, University of Illinois College of Medicine, Peoria, IL, USA.

Purpose: The treatment of gastroschisis (GS) using our collaborative clinical pathway, with immediate attempted abdominal closure and bowel irrigation with a mucolytic agent, was reviewed.

Methods: A retrospective review of the past 20 years of our clinical pathway was performed on neonates with GS repair at our institution. The clinical treatment includes attempted complete reduction of GS defect within 2 h of birth. Read More

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November 2018
4 Reads

Rare diseases mortality in Colombia, 2008-2013

Biomedica 2018 06 15;38(2):198-208. Epub 2018 Jun 15.

Centro de Investigación y Atención en Salud del Magdalena Medio, CISMAG, Barrancabermeja, Colombia.

Introduction: Rare diseases are characterized by their low prevalence, often of genetic origin, degenerative and life threatening. Objective: To describe mortality by orphan diseases and to analyze its trends in Colombia from 2008 to 2013. Materials and methods: We conducted a descriptive study to analyze mortality rate trends from the death certificates between 2008 and 2013. Read More

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The association between gestational age at delivery, closure type and perinatal outcomes in neonates with isolated gastroschisis.

J Matern Fetal Neonatal Med 2018 Oct 1:1-7. Epub 2018 Oct 1.

a Department of Obstetrics and Gynecology , Medical College of Wisconsin , Milwaukee , WI , USA.

Objective: The objective of this study was to examine the association between gestational age at delivery and closure type for neonates with gastroschisis. In addition, we compared perinatal outcomes among the cases of gastroschisis based on the following two factors: gestational age at delivery and abdominal wall closure technique.

Methods: This was a retrospective cohort study of all fetuses with isolated gastroschisis that were diagnosed prenatally and delivered between September 2000 and January 2017, in a single tertiary care center. Read More

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October 2018
1 Read

Association between early prenatal exposure to ambient air pollution and birth defects: evidence from newborns in Xi'an, China.

J Public Health (Oxf) 2018 Aug 18. Epub 2018 Aug 18.

Xi'an Jiaotong University, Health Science Center, No. 76, Yanta West Road, Xi'an, Shaanxi Province, PR China.

Background: The aim of this study was to investigate an association between birth defects and exposure to sulfur dioxide (SO2), nitrogen dioxide (NO2) and particles ≤10 μm in an aerodynamic diameter (PM10) during early pregnancy in Xi'an, China.

Methods: Birth defect data were from the Birth Defects Monitoring System of Xi'an, and data on ambient air pollutants during 2010-15 were from the Xi'an Environmental Protection Bureau. A generalized additive model (GAM) was used to investigate the relationship between birth defects and ambient air pollutants. Read More

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August 2018
2 Reads
2.300 Impact Factor

[Descriptive epidemiology of major structural congenital anomalies in Argentina].

Medicina (B Aires) 2018 ;78(4):252-257

Red Nacional de Anomalías Congénitas de Argentina (RENAC), Centro Nacional de Genética Médica, Administración Nacional de Laboratorios e Institutos de Salud (A.N.L.I.S.), Ministerio de Salud de la Nación, Buenos Aires, Argentina.

The objective of the study is to present the frequency of congenital anomalies (CA) reported to the National Network of Congenital Anomalies of Argentina (RENAC) in the year 2016, as part of its monitoring activities. RENAC is an official, national and hospital-based surveillance system of CA. The case definition includes newborns with major structural CA, external or internal, identified from birth until hospital discharge and detected by physical examination, complementary studies, interventions or autopsy. Read More

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January 2018
8 Reads

Use of Breast Milk and Other Feeding Practices Following Gastrointestinal Surgery in Infants.

J Pediatr Gastroenterol Nutr 2018 Aug 16. Epub 2018 Aug 16.

The Johns Hopkins School of Medicine, Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baltimore, Maryland.

Objectives: To characterize the enteral feeding practices in infants following gastrointestinal surgery.

Methods: We performed a retrospective analysis of infants who underwent intestinal surgery at age <6 months who survived to be fed enterally between January 2012-June 2017. Demographics, surgical characteristics, feeding practices, and growth-related outcomes during hospitalization, discharge, and follow-up (three-, six-, and twelve-months) were obtained from the electronic medical records. Read More

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August 2018
7 Reads

A clinical-pathogenetic approach on associated anomalies and chromosomal defects supports novel candidate critical regions and genes for gastroschisis.

Pediatr Surg Int 2018 Sep 9;34(9):931-943. Epub 2018 Aug 9.

Departamento de Genética, Facultad de Medicina y Hospital Universitario José Eleuterio González, Universidad Autónoma de Nuevo León, Ave. Madero y Gonzalitos S/N Col. Mitras Centro, CP 64460, Monterrey, Nuevo León, México.

Background: Gastroschisis has been assumed to have a low rate of syndromic and primary malformations. We aimed to systematically review and explore the frequency and type of malformations/chromosomal syndromes and to identify significant biological/genetic roles in gastroschisis.

Methods: Population-based, gastroschisis-associated anomalies/chromosomal defects published 1950-2018 (PubMed/MEDLINE) were independently searched by two reviewers. Read More

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September 2018
27 Reads
1.061 Impact Factor

Trends in incidence and outcomes of gastroschisis in the United States: analysis of the national inpatient sample 2010-2014.

Pediatr Surg Int 2018 Sep 28;34(9):919-929. Epub 2018 Jul 28.

Department of Pediatrics, University of Washington, 4800 Sand Point Way NE, Seattle, WA, 98105, USA.

Purpose: Gastroschisis is a severe congenital anomaly associated with a significant morbidity and mortality. There are limited temporal trend data on incidence, mortality, length of stay, and hospital cost of gastroschisis. Our aim was to study these temporal trends using the National Inpatient Sample (NIS). Read More

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September 2018

Incidence of Gastroschisis in California.

JAMA Surg 2018 Nov;153(11):1053-1055

Division of Pediatric General, Thoracic, and Fetal Surgery, University of California Davis Medical Center, Sacramento.

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November 2018

Early Detection of Structural Anomalies in a Primary Care Setting in the Netherlands.

Fetal Diagn Ther 2018 Jul 25:1-8. Epub 2018 Jul 25.

Fetal Medicine Unit, Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Objective: This study assessed the percentage and type of congenital anomalies diagnosed at first-trimester ultrasound (US) scan in a primary care setting without following a standardized protocol for fetal anatomical assessment.

Materials And Methods: US scans performed between 11+0 and 13+6 weeks of gestation in pregnancies with estimated date of delivery between January 1, 2012 and January 1, 2016 were searched. Data were supplemented with results of 20-week scans and pregnancy outcome. Read More

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July 2018
4 Reads

Rectal Levothyroxine for the Treatment of Hypothyroidism: A Case Study.

Pediatrics 2018 Aug 12;142(2). Epub 2018 Jul 12.

Pediatric Endocrinology Unit, Children's Institute, University of São Paulo, São Paulo, Brazil.

Transient hypothyroidism can present itself as clinically asymptomatic or with few symptoms. Early treatment with levothyroxine (L-T4) prevents complications related to this disorder. We report a case of a male infant with concomitant short bowel syndrome and transient hypothyroidism treated with rectal L-T4. Read More

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August 2018
5 Reads

Long-term Quality of Life in Neonatal Surgical Disease.

Ann Surg 2018 Sep;268(3):497-505

Children's Hospital of Wisconsin and Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.

Objective: This prospective observational study was designed to assess Pediatric Quality of Life (PedsQL) after surgical treatment for congenital diaphragmatic hernia (CDH), esophageal atresia/tracheoesophageal fistula (EA/TEF), Hirschsprung disease (HD), gastroschisis (GAS), omphalocele (OMP), and necrotizing enterocolitis (NEC).

Summary Of Background Data: Improvements in neonatal and surgical care have led to increased survival for many newborn conditions. Quality of life in these patients is seldom explored in a longitudinal manner. Read More

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September 2018
4 Reads

Evaluation of the fetal abdomen by magnetic resonance imaging. Part 2: abdominal wall defects and tumors.

Radiol Bras 2018 May-Jun;51(3):187-192

Tenured Adjunct Professor in the Department of Obstetrics of the Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brazil.

Although ultrasound is still the gold standard for the assessment of fetal malformations, magnetic resonance imaging (MRI) has gained great prominence in recent years. In situations in which ultrasound has low sensitivity, such as maternal obesity, abdominal scarring, and oligohydramnios, MRI has proven to be a safe and accurate method. Regarding fetal abdominal wall defects, MRI appears to be widely used in the prognostic assessment of gastroschisis with intestinal atresia or of complications of omphalocele, allowing better perinatal management and parental counseling. Read More

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July 2018
11 Reads

Vanishing gastroschisis visualized by antenatal ultrasound: a case report and review of literature.

Eur J Obstet Gynecol Reprod Biol 2018 Sep 19;228:186-190. Epub 2018 Jun 19.

Department of Obstetrics, Saint-Luc University Hospital, Brussels, Belgium. Electronic address:

We report a case of vanishing gastroschisis visualized by antenatal ultrasound with a 7-year long term follow-up. Currently, the child is still dependent on daily parenteral nutrition with no signs of hepatotoxicity. To our knowledge, it's the fourth case with a long-term follow-up. Read More

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September 2018
1 Read

What can make things better for parents when babies need abdominal surgery in their first year of life? A qualitative interview study in the UK.

BMJ Open 2018 Jun 30;8(6):e020921. Epub 2018 Jun 30.

Nuffield Department of Population Health, National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.

Objectives: To understand the experiences of parents of infants who required surgery early in life. To identify messages and training needs for the extended clinical teams caring for these families-including paediatric surgeons, neonatologists, nurses, obstetricians, midwives and sonographers.

Setting: UK-wide interview study, including England, Wales and Scotland. Read More

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June 2018
8 Reads

Complexity of gastroschisis predicts outcome: epidemiology and experience in an Australian tertiary centre.

BMC Pregnancy Childbirth 2018 Jun 11;18(1):222. Epub 2018 Jun 11.

Westmead Institute for Maternal and Fetal Medicine, Women's and Newborn Health, Westmead Hospital, Research & Education Network Building, Hawkesbury Rd, PO Box 533, Westmead, NSW, 2145, Australia.

Background: Gastroschisis is a congenital anomaly of the fetal abdominal wall, usually to the right side of umbilical insertion. It is often detected by routine antenatal ultrasound. Significant maternal and pediatric resources are utilised in the care of women and infants with gastroschisis. Read More

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June 2018
2 Reads

Small bowel obstruction caused by vas deferens: a first documented report.

BMJ Case Rep 2018 Jun 6;2018. Epub 2018 Jun 6.

Gastrointestinal surgery, Royal Cornwall Hospitals NHS Trust, Truro, Cornwall, United Kingdom.

Small bowel obstruction (SBO) is one of the most common causes for an acute surgical admission. Most of the time SBO is a result of common causes such as postoperative adhesions. However, rare and unusual causes of SBO do exist which can be challenging for surgeons. Read More

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June 2018
2 Reads

Gastroschisis and Cumulative Stressor Exposures.

Epidemiology 2018 09;29(5):721-728

From the Boston University School of Public Health, Boston, MA.

Background: Gastroschisis, a congenital defect of the abdominal wall, occurs disproportionately more in offspring of young mothers and has been increasing in prevalence over the past decades. A wide range of exposures have been reported in association with an increased gastroschisis risk, independent of mother's age; many have also been correlated with stress responses.

Methods: We explored cumulative exposures to such stressor exposures among 1,261 mothers of gastroschisis cases and 10,682 mothers of controls in the National Birth Defects Prevention Study (1997-2011). Read More

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September 2018

A Giant Gastroschisis Associated with Pulmonary Hypoplasia and Spinal Anomaly: A Case Report and a Literature Review.

Case Rep Pathol 2018 2;2018:8378769. Epub 2018 May 2.

Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Gastroschisis most often occurs as an isolated anomaly and extragastrointestinal associations are rare. Most commonly, the anomalies associated with gastroschisis are cardiac and central nervous system abnormalities. Respiratory insufficiency has sometimes been reported in association with giant abdominal wall defects. Read More

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May 2018
1 Read

Early Life Incidence of Gastrointestinal and Respiratory Infections in Children With Gastroschisis: A Cohort Study.

J Pediatr Gastroenterol Nutr 2018 Nov;67(5):580-585

NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust.

Objectives: Survival in infants with gastroschisis is increasing although little is known about early childhood morbidity. In the context of a hypothesized link between the gastrointestinal (GI) tract and immune function, this study explores rates of GI and respiratory infections in children with gastroschisis.

Methods: We conducted a population-based retrospective cohort study using data from the Health Improvement Network, a large database of UK primary care medical records. Read More

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November 2018
1 Read
2.620 Impact Factor

Meconium-stained amniotic fluid as a predictor of poor outcomes in gastroschisis.

J Pediatr Surg 2018 Sep 27;53(9):1665-1668. Epub 2018 Apr 27.

Pediatric Surgery, Children's Hospital of Wisconsin.

Objective: The aim of this study was to determine if meconium-stained amniotic fluid (MSAF) was associated with neonatal outcomes in gastroschisis.

Study Design: A retrospective chart review of gastroschisis patients from 2000 to 2014 at a single, tertiary institution was performed. Statistical analysis was performed with Fisher exact test, Welch's t-test, logistic regression and/or linear regression with significance at p < 0. Read More

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September 2018
9 Reads

The factors associated with successful early enteral feeding in gastroschisis.

Pediatr Surg Int 2018 Jul 25;34(7):743-748. Epub 2018 May 25.

Division of Pediatric Surgery, Department of Surgery, Chiang Mai University Hospital, 110 Intavaroros Road, Muang Chiang Mai District, Chiang Mai, 50200, Thailand.

Background: Gastroschisis is the most common congenital abdominal wall defect. Due to the exposure of midgut to amniotic fluid, the recovery of bowel function is often delayed. This study aimed to identify the factors associated with the successful early enteral feeding in gastroschisis and to develop further guidelines of treatment. Read More

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Stomach herniation prior to nonreassuring fetal status in a case of fetal gastroschisis.

J Obstet Gynaecol Res 2018 Jul 23;44(7):1322-1325. Epub 2018 May 23.

Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.

The neonatal prognosis in gastroschisis is generally good; however, intrauterine fetal death (IUFD) and nonreassuring fetal status (NRFS) sometimes occur in fetal cases of gastroschisis. Previously, we reported stomach herniation as a possible risk factor for IUFD or NRFS in fetuses with gastroschisis. We report a case of fetal gastroschisis showing stomach herniation and increased velocity of the umbilical venous (UV) flow the day before NRFS by electronic fetal monitoring (EFM). Read More

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July 2018
3 Reads

National Practice Patterns for Prenatal Monitoring in Gastroschisis: Gastroschisis Outcomes of Delivery (GOOD) Provider Survey.

Fetal Diagn Ther 2018 May 23:1-6. Epub 2018 May 23.

Pediatric Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

Background: Gastroschisis is an abdominal wall defect with increasing incidence. Given the lack of surveillance guidelines among maternal-fetal medicine (MFM) specialists, this study describes current practices in gastroschisis management.

Materials And Methods: An online survey was administered to MFM specialists from institutions affiliated with the North American Fetal Therapy Network (NAFTNet). Read More

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May 2018
3 Reads

Clinical features and practice patterns of gastroschisis: a retrospective analysis using a Japanese national inpatient database.

Pediatr Surg Int 2018 May 16. Epub 2018 May 16.

Department of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Purpose: The number of infants with gastroschisis is increasing worldwide, but advances in neonatal intensive care and parenteral nutrition have reduced gastroschisis mortality. Recent clinical data on gastroschisis are often from Western nations. This study aimed to examine clinical features and practice patterns of gastroschisis in Japan. Read More

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Dichorionic twins discordant for body-stalk anomaly: a management challenge.

BMJ Case Rep 2018 May 12;2018. Epub 2018 May 12.

Department of Pathology, CGC Genetics Centro de Genetica Clinica, Porto, Portugal.

Body-stalk anomaly is a sporadic and rare maldevelopment disorder characterised by large abdominal wall defect, spinal deformity and rudimentary umbilical cord. It is considered a lethal condition as there are only few reports of survival but there was at least one case of long-term survival after neonatal surgery.Differential diagnosis includes isolated omphalocele or gastroschisis, short umbilical cord, amniotic band, limb body-wall complex and other polymalformative syndromes. Read More

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May 2018
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Epidemiology of septo-optic dysplasia with focus on prevalence and maternal age - A EUROCAT study.

Eur J Med Genet 2018 Sep 10;61(9):483-488. Epub 2018 May 10.

Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK.

Septo-optic nerve dysplasia is a rare congenital anomaly with optic nerve hypoplasia, pituitary hormone deficiencies and midline developmental defects of the brain. The clinical findings are visual impairment, hypopituitarism and developmental delays. The aim of this study was to report prevalence, associated anomalies, maternal age and other epidemiological factors from a large European population based network of congenital anomaly registries (EUROCAT). Read More

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September 2018
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