760 results match your criteria Gastrointestinal Reflux Imaging


The Rationale and Efficacy of Primary and Secondary Prevention in Adenocarcinomas of the Upper Gastrointestinal Tract.

Dig Dis 2019 Apr 10:1-13. Epub 2019 Apr 10.

Department of Gastroenterology, Hepatology and Infectious Disease, Otto-von-Guericke University, Magdeburg, Germany.

While the primary risk factor for oesophageal adenocarcinoma (OAC) and its precursor lesion Barrett's oesophagus (BO) is gastro-oesophageal reflux, the infection with Helicobacter pylori (H. pylori) is the dominant risk factor for gastric cancer. Reduction of reflux by dietary measures and proton pump inhibitors has some merits in OAC prevention, and the chemopreventive effect of Aspirin and statins is being widely investigated; however, improved outcome in OAC occurs primarily as the result of secondary prevention. Read More

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http://dx.doi.org/10.1159/000499706DOI Listing
April 2019
1 Read

Barrett's Esophagus and Esophageal Carcinoma: Can Biomarkers Guide Clinical Practice?

Curr Gastroenterol Rep 2019 Mar 12;21(4):14. Epub 2019 Mar 12.

Department of Medicine and the Center for Esophageal Diseases, Baylor University Medical Center, Dallas, TX, 75246, USA.

Purpose Of Review: Despite gastrointestinal societal recommendations for endoscopic screening and surveillance of Barrett's esophagus, the rates of esophageal adenocarcinoma continue to rise. Furthermore, this current practice is costly to patients and the medical system without clear evidence of reduction in cancer mortality. The use of biomarkers to guide screening, surveillance, and treatment strategies might alleviate some of these issues. Read More

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http://dx.doi.org/10.1007/s11894-019-0685-6DOI Listing
March 2019
2 Reads

Real-time MRI for the dynamic assessment of fundoplication failure in patients with gastroesophageal reflux disease.

Eur Radiol 2019 Feb 25. Epub 2019 Feb 25.

Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.

Purpose: To assess the diagnostic potential of dynamic real-time MRI for fundoplication failure in patients with persistent or recurrent GERD-like (gastroesophageal reflux disease) complaints.

Material And Methods: Twenty-two consecutive patients (male n = 11; female n = 11; median age 59 years) with recurrent or persistent GERD-like symptom after fundoplication were enrolled between 2015 and 2017. Median duration of GERD-like symptoms was 21 months. Read More

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http://dx.doi.org/10.1007/s00330-019-06025-xDOI Listing
February 2019
2 Reads

Incidentally discovered intestinal nonrotation at time of bariatric surgery: Which operation to perform?

Surg Obes Relat Dis 2019 Jan 11. Epub 2019 Jan 11.

Department of Surgery, Queen's University, Kingston, Ontario, Canada. Electronic address:

Background: An incidental finding of intestinal nonrotation at the time of bariatric surgery poses the following 2 dilemmas: (1) which operation to perform, and (2) whether an appendectomy should be performed concurrently.

Objectives: To review the experience of 2 Bariatric Centers of Excellence with laparoscopic sleeve gastrectomy (LSG) in patients with intestinal nonrotation, and to perform a systematic review of the literature on this topic.

Setting: Two Bariatric Centers of Excellence as designated by the Ontario Bariatric Network. Read More

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http://dx.doi.org/10.1016/j.soard.2018.12.036DOI Listing
January 2019
2 Reads

New Developments in Esophageal Motility Testing.

Curr Treat Options Gastroenterol 2019 Mar;17(1):76-88

University of Colorado Reflux & Esophageal Diseases Center, Division of Gastroenterology & Hepatology, Department of Medicine, University of Colorado, Anschutz Medical Campus, Academic Office 1 Room 7605, 12631 E. 17th Ave, Aurora, CO, 80045, USA.

Purpose Of Review: The purpose of this review is to present the latest developments in esophageal motility testing and summarize the current paradigm of esophageal motility disorders.

Recent Findings: While high-resolution esophageal pressure topography interpreted according to the Chicago Classification represents the gold standard to evaluate esophageal motility, recent studies highlight the additional value of novel manometric applications. Novel applications include provocative measures to assess for obstructive physiology at the esophagogastric junction (EGJ), esophageal peristaltic reserve, and rumination and supragastric belching disorders. Read More

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http://link.springer.com/10.1007/s11938-019-00218-5
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http://dx.doi.org/10.1007/s11938-019-00218-5DOI Listing
March 2019
20 Reads

Predictors of Hiatal Hernia Recurrence After Laparoscopic Anti-reflux Surgery with Hiatal Hernia Repair: a Prospective Database Analysis.

J Gastrointest Surg 2019 Apr 7;23(4):696-701. Epub 2019 Jan 7.

Center for Advanced Surgical Technology, University of Nebraska Medical Center, 986246 Nebraska Medical Center, Omaha, NE, 68198-6246, USA.

Background: The aim of this study is to identify factors that can predict hiatal hernia recurrence (HHR) in patients after anti-reflux surgery with hiatal hernia (HH) repair.

Methods: A single-institution, prospectively collected database was reviewed (January 2002-October 2015) with inclusion criteria of GERD and laparoscopic anti-reflux (AR) surgery with HH repair. Demographics, esophageal symptom scores, and pre- and post-upper gastrointestinal imaging (UGI) were collected. Read More

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http://dx.doi.org/10.1007/s11605-018-04073-0DOI Listing
April 2019
4 Reads

Primary gastric inflammatory myofibroblastic tumor: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13423

Department of Radiology, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, People's Republic of China.

Rationale: Primary gastric inflammatory myofibroblastic tumor is extremely rare. Only a few cases were reported in the domestic and foreign medical literature with corresponding imaging findings of this disease even more rarely reported.

Patient Concerns: We present one case of a 52-year-old female patient with upper abdominal pain, acid reflux, and belching for 2 months. Read More

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http://dx.doi.org/10.1097/MD.0000000000013423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320093PMC
December 2018
2 Reads
5.723 Impact Factor

Establishment of a novel and effective reflux laryngitis model in rabbits: a preliminary study.

Eur Arch Otorhinolaryngol 2019 Jan 10;276(1):175-183. Epub 2018 Dec 10.

The Department of Otolaryngology-Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200030, China.

Purpose: To establish a novel and effective reflux model with a modified nasogastric aspiration tube and to investigate the association between different types of nasogastric aspiration tubes and reflux laryngitis, we conducted this study.

Methods: Thirty-eight healthy New Zealand albino rabbits (2.5-3. Read More

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http://link.springer.com/10.1007/s00405-018-5234-7
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http://dx.doi.org/10.1007/s00405-018-5234-7DOI Listing
January 2019
18 Reads

Preoperative gastric residual volumes in fasted patients measured by bedside ultrasound: a prospective observational study.

Anaesth Intensive Care 2018 Nov;46(6):608-613

Clinical Professor, School of Medicine and Pharmacology, University of Western Australia; Raine Clinical Research Fellow, Raine Foundation/WA Health Department; Adjunct Clinical Professor, School of Public Health and Preventive Medicine, Monash University Australia; Perth, Western Australia.

The purpose of this prospective observational study was to measure gastric volumes in fasted patients using bedside gastric ultrasound. Patients presenting for non-emergency surgery underwent a gastric antrum assessment, using the two-diameter and free-trace methods to determine antral cross-sectional area (CSA). Gastric residual volume (GRV) was calculated using a validated formula. Read More

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http://dx.doi.org/10.1177/0310057X1804600612DOI Listing
November 2018

Ingestible Contrast Agents for Gastrointestinal Imaging.

Chembiochem 2019 Feb 8;20(4):462-473. Epub 2019 Jan 8.

School of Chemical Engineering and Technology, Tianjin University, Tianjin, 301636, China.

Gastrointestinal (GI) ailments cover a wide variety of diseases involving the esophagus, stomach, small intestine, large intestine, and rectum. They bring about many inconveniences in daily life in chronic diseases and can even be life threatening in acute cases. Rapid and safe detection approaches are essential for early diagnosis and timely management. Read More

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http://doi.wiley.com/10.1002/cbic.201800589
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http://dx.doi.org/10.1002/cbic.201800589DOI Listing
February 2019
18 Reads

Pneumomediastinum as a complication of esophageal intramural pseudodiverticulosis.

Acta Gastroenterol Belg 2018 Jul-Sep;81(3):433-435

Department of Gastroenterology, University Hospitals Gasthuisberg, Leuven, Belgium.

Dysphagia is a common complaint of patients seen at the outpatient clinic as well as at the emergency room. We report esophageal intramural pseudodiverticulosis (EIPD) as a cause of dysphagia that is less known by physicians and it is rarely described in the literature. EIPD is characterized by multiple, segmental or diffuse, flask-like outpouchings in the esophageal wall corresponding to dilated and inflamed excretory ducts of the submucosal esophageal glands. Read More

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February 2019
3 Reads

The effect of gender differences in protracted hiccups.

Authors:
O Eroglu

Niger J Clin Pract 2018 Oct;21(10):1356-1360

Department of Emergency Medicine, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

Background: Although little importance is attached to hiccups, they may be associated with several diseases. The purpose of this study was to investigate the effects of gender differences on types of hiccups and the relation with diseases involved in the etiology.

Materials And Methods: Patients presenting to the Kirikkale University Medical Faculty Hospital with hiccups were investigated retrospectively. Read More

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http://dx.doi.org/10.4103/njcp.njcp_101_18DOI Listing
October 2018
3 Reads

Large mesenteric lymphangioma in an adult patient: an unusual presentation of a rare disease.

BMJ Case Rep 2018 Oct 7;2018. Epub 2018 Oct 7.

Department of Surgery, Duke University Hospital, Durham, North Carolina, USA.

Lymphangiomas are most commonly described as a small painless mass in the neck or a vesicular rash in an infant patient. Ninety per cent of cases are diagnosed before the age of 2. Treatment usually involves surgical resection. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22631
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http://dx.doi.org/10.1136/bcr-2018-226319DOI Listing
October 2018
8 Reads

Once Upon a Time in the Esophagus.

Gastroenterology 2019 03 6;156(4):874-875. Epub 2018 Oct 6.

Department of Upper GI Diseases, Gastrointestinal Endoscopy Unit, Karolinska University Hospital, Stockholm, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183509
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http://dx.doi.org/10.1053/j.gastro.2018.10.002DOI Listing
March 2019
24 Reads

Evaluating the yield of gastrointestinal testing in pediatric patients in aerodigestive clinic.

Pediatr Pulmonol 2018 Nov 4;53(11):1517-1524. Epub 2018 Oct 4.

University of Colorado School of Medicine, Department of Pediatrics, Aurora, Colorado.

Objective: To improve understanding of the interrelatedness of airway and esophageal diagnoses by evaluating the yield of procedural and radiographic testing of the gastrointestinal tract in children with airway conditions by their referring diagnoses in a pediatric aerodigestive clinic.

Methods: A retrospective chart review of all 325 patients seen in the aerodigestive program from 2010 to 2013 was performed in a single academic medical center. Demographics and results from esophagogastroduodenoscopies with biopsies (EGD), upper gastrointestinal fluoroscopy studies (UGI), and pH multichannel intraluminal impedance probe (pH-MII) performed within 30 days of the clinic visit were evaluated according to presenting diagnoses. Read More

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http://doi.wiley.com/10.1002/ppul.24170
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http://dx.doi.org/10.1002/ppul.24170DOI Listing
November 2018
6 Reads

Surgical Management of Gastroesophageal Reflux Disease in Patients with Severe Esophageal Dysmotility.

J Gastrointest Surg 2019 Jan 4;23(1):36-42. Epub 2018 Oct 4.

Center for Advanced Surgical Technology, University of Nebraska Medical Center, 986246 Nebraska Medical Center, Omaha, NE, 68198-6246, USA.

Background: Gastroesophageal reflux disease (GERD) and esophageal dysmotility are often disqualifying criteria for fundoplication due to dysphagia complications. A tailored partial fundoplication may improve GERD in patients with severe esophageal motility disorders. We evaluate this approach on GERD improvement in non-achalasia esophageal dysmotility patients. Read More

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http://link.springer.com/10.1007/s11605-018-3968-6
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http://dx.doi.org/10.1007/s11605-018-3968-6DOI Listing
January 2019
15 Reads

Massive gastric dilatation leading to acute respiratory distress 1 year after a Nissen fundoplication.

BMJ Case Rep 2018 Sep 27;2018. Epub 2018 Sep 27.

Surgery, BHR Hospitals Trust, Romford, UK.

Acute massive gastric dilatation (AMGD) is a recognised complication after Nissen fundoplication. A 63-year-old man recently presented to our emergency department in acute respiratory distress, acute abdominal pain and distension, having had an elective umbilical port incisional hernia repair a day prior. In the year preceding his presentation, the patient had undergone a laparoscopic paraoesophageal hiatus hernia repair and excision of sac, posterior cruropexy, dual mesh reinforcement of repair and 360° fundoplication, as a day case. Read More

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http://dx.doi.org/10.1136/bcr-2018-225927DOI Listing
September 2018
3 Reads

Serum anti- antibody titer and its association with gastric nodularity, atrophy, and age: A cross-sectional study.

World J Gastroenterol 2018 Sep;24(35):4061-4068

Medical Education Center, Keio University School of Medicine, Tokyo 160-8582, Japan.

Aim: To clarify the role of serum anti- () antibody titers in gastric cancer.

Methods: In this cross-sectional study, the effect of patients' baseline characteristics and endoscopic findings on their serum antibody titers were assessed. We evaluated consecutive patients who underwent esophagogastroduodenoscopy and their first evaluation for infection using a serum antibody test. Read More

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http://dx.doi.org/10.3748/wjg.v24.i35.4061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148426PMC
September 2018
14 Reads

Hypertrophic pyloric stenosis following repair of oesophageal atresia and tracheo-oesophageal fistula in a neonate.

BMJ Case Rep 2018 Sep 21;2018. Epub 2018 Sep 21.

Department of Pediatric Surgery, School of Medicine, Harran University, Sanliurfa, Turkey.

Development of hypertrophic pyloric stenosis (HPS) after a few weeks of repair of an oesophageal atresia (OA) and tracheo-oesophageal fistula (TOF) is a rare condition in early infancy. Although vomiting or feeding intolerance in operated cases of OA+TOF are attributed to oesophageal stricture, gastro-oesophageal reflux and oesophageal dysmotility, it may also be caused by HPS. Herein, we report a newborn infant who had OA and TOF operation on day 2 of life and diagnosed to have HPS at 15th day of age. Read More

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420448/
Web Search
https://link.springer.com/content/pdf/10.1007%2FBF02664059.p
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http://europepmc.org/articles/PMC4420448
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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22629
Publisher Site
http://dx.doi.org/10.1136/bcr-2018-226292DOI Listing
September 2018
13 Reads

Percutaneous transhepatic extraction and balloon dilation for simultaneous gallbladder stones and common bile duct stones: A novel technique.

World J Gastroenterol 2018 Sep;24(33):3799-3805

Department of Interventional Medicine, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China.

Aim: To evaluate the clinical efficacy and safety of an innovative percutaneous transhepatic extraction and balloon dilation (PTEBD) technique for clearance of gallbladder stones in patients with concomitant stones in the common bile duct (CBD).

Methods: The data from 17 consecutive patients who underwent PTEBD for clearance of gallbladder stones were retrospectively analyzed. After removal of the CBD stones by percutaneous transhepatic balloon dilation (PTBD), the gallbladder stones were extracted to the CBD and pushed into the duodenum with a balloon after dilation of the sphincter of Oddi. Read More

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http://dx.doi.org/10.3748/wjg.v24.i33.3799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127656PMC
September 2018
11 Reads
2.370 Impact Factor

Gastrointestinal Bleed from Erosive Gastritis and Duodenitis: A Sentinel Event of Invasive Lobular Carcinoma of the Breast and a Diagnostic Dilemma.

Cureus 2018 Jun 7;10(6):e2757. Epub 2018 Jun 7.

Hematology-Oncology, University of Nevada Reno, School of Medicine, Reno, USA.

Metastasis from breast cancer to the gastrointestinal (GI) tract is uncommon, and such events presenting as GI bleeding are exceedingly rare. In some individuals, the absence of classical findings of primary breast cancer coupled with the non-specific nature of GI symptoms may make early detection and diagnosis challenging. Our patient is a 75-year-old female who presented with symptomatic anemia manifesting as progressive dizziness, weakness, and early satiety that developed eight days after right knee arthroplasty. Read More

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http://dx.doi.org/10.7759/cureus.2757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080734PMC
June 2018
2 Reads

Acceptability, Accuracy, and Safety of Disposable Transnasal Capsule Endoscopy for Barrett's Esophagus Screening.

Clin Gastroenterol Hepatol 2019 Mar 3;17(4):638-646.e1. Epub 2018 Aug 3.

National Institute for Health Research Biomedical Research Center in Gastrointestinal and Liver Diseases at Nottingham University Hospitals NHS Trust and the University of Nottingham, Queens Medical Center Campus, Nottingham, United Kingdom. Electronic address:

Background & Aims: Screening for Barrett's esophagus (BE) with conventional esophagogastroduodenoscopy (C-EGD) is expensive. We assessed the performance of a clinic-based, single use transnasal capsule endoscope (EG Scan II) for the detection of BE, compared to C-EGD as the reference standard.

Methods: We performed a prospective multicenter cohort study of patients with and without BE recruited from 3 referral centers (1 in the United States and 2 in the United Kingdom). Read More

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http://dx.doi.org/10.1016/j.cgh.2018.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330075PMC
March 2019
38 Reads
7.900 Impact Factor

Barrett's esophagus and gland cancer - the experience of one center.

Pol Przegl Chir 2018 May;90(3):19-24

Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun.

Objective: The aim of the study was to evaluate the prevalence and clinical aspects of Barrett's esophagus and adenocarcinoma of the lower part of esophagus in gastroscopy.

Material And Methods: Retrospective review of 10000 upper gastrointestinal endoscopic examinations were performed at the Department of Oncology Endoscopy in Bydgoszcz from 2004 to 2014 in terms of incidence of Barrett's esophagus and adenocarcinoma in the lower part of esophagus.

Results: The medical records of 5378 (53. Read More

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http://dx.doi.org/10.5604/01.3001.0011.8166DOI Listing
May 2018
22 Reads

Barrett's Esophagus in Patients with Gastroesophageal Reflux Disease.

J Nepal Health Res Counc 2018 Jul 3;16(2):144-148. Epub 2018 Jul 3.

Department of Gastroenterology, College of Medical Sciences Teaching Hospital, Bharatpur, Chitwan, Nepal.

Background: Barrett's esophagus a is metaplasia of normal squamous cells that line the lower part of the esophagus and carries a major risk for adenocarcinoma of esophagus. In Asian population, the prevalence of Barrett's esophagus and adenocarcinoma are less common than in Western countries but has been increasing.

Methods: This is a hospital based descriptive study comprising of 120 consecutive patients with symptoms of gastroesophagial reflux disease belonging to both sexes of any age group. Read More

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July 2018
4 Reads

The esophagiome: integrated anatomical, mechanical, and physiological analysis of the esophago-gastric segment.

Ann N Y Acad Sci 2018 Dec 10;1434(1):5-20. Epub 2018 Jun 10.

GIOME, Department of Surgery, Prince of Wales Hospital and Chinese University of Hong Kong, Shatin, Hong Kong SAR.

Esophageal diseases are highly prevalent and carry significant socioeconomic burden. Despite the apparently simple function of the esophagus, we still struggle to better understand its physiology and pathophysiology. The assessment of large data sets and application of multiscale mathematical organ models have gained attention as part of the Physiome Project. Read More

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http://dx.doi.org/10.1111/nyas.13869DOI Listing
December 2018
6 Reads

Intra- and interobserver variability in the diagnosis of GERD by real-time MRI.

Eur J Radiol 2018 Jul 27;104:14-19. Epub 2018 Apr 27.

Department of Diagnostic and Interventional Radiology, University Medical Center, Göttingen, Germany.

The purpose of this study was to assess the reproducibility of functional and anatomical parameters of swallowing events as determined by real-time MRI at 40 ms temporal resolution (25 frames per second). Twenty-three consecutive patients with gastroesophageal reflux disease (GERD) underwent real-time MRI of the gastroesophageal junction at 3.0 T. Read More

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http://dx.doi.org/10.1016/j.ejrad.2018.04.029DOI Listing
July 2018
2 Reads

Delayed diagnosis of a case of Zenker's diverticulum. What may happen when a family physician does not visit his family physician.

Eur J Gen Pract 2018 Dec;24(1):151-154

b Department of Thoracic Surgery , Ataturk University Medical Faculty , Erzurum , Turkey.

Introduction: Zenker's diverticulum is a diverticulum of the mucosa of the pharynx, just above the cricopharyngeal muscle. It occurs commonly in elderly patients (over 70 years) and the typical symptoms include dysphagia, regurgitation, chronic cough, aspiration and weight loss.

Case: We are reporting dysphagia in a 49-years old man who was treated as having Helicobacter Pylori gastritis for three years. Read More

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http://dx.doi.org/10.1080/13814788.2018.1464556DOI Listing
December 2018
6 Reads

Tailored Fundoplication With Endoluminal Functional Lumen Imaging Probe Allows for Successful Minimally Invasive Hiatal Hernia Repair.

Surg Laparosc Endosc Percutan Tech 2018 Jun;28(3):178-182

Department of Surgery, Division of Thoracic Surgery.

Endoluminal functional lumen imaging probe (EndoFLIP) can provide real time information about characteristics of the gastroesophageal junction. We performed retrospective analysis of prospectively collected data on use of EndoFLIP during minimally invasive hiatal hernia repair to tailor the size of the crural closure and size of the fundoplication. We then determined whether it provides good reflux control without significant dysphagia. Read More

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http://Insights.ovid.com/crossref?an=00129689-900000000-9952
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http://dx.doi.org/10.1097/SLE.0000000000000527DOI Listing
June 2018
49 Reads

Four cancer cases after esophageal atresia repair: Time to start screening the upper gastrointestinal tract.

World J Gastroenterol 2018 Mar;24(9):1056-1062

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam 3000 CA, Netherlands.

Esophageal atresia (EA) is one of the most common congenital digestive malformations and requires surgical correction early in life. Dedicated centers have reported survival rates up to 95%. The most frequent comorbidities after EA repair are dysphagia (72%) and gastroesophageal reflux (GER) (67%). Read More

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http://dx.doi.org/10.3748/wjg.v24.i9.1056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840470PMC
March 2018
7 Reads

The impact of preoperative investigations on the management of bariatric patients; results of a cohort of more than 1200 cases.

Surg Obes Relat Dis 2018 05 12;14(5):693-699. Epub 2018 Jan 12.

Department of Surgery, St. Claraspital AG, Basel, Switzerland.

Background: Despite the increasing use of bariatric surgery as the most effective treatment of morbid obesity, there is still no consensus on its preoperative diagnostic workup. The aim of this study was to identify the pathologies of the endoscopic and radiologic investigations before performing bariatric surgery and to evaluate their impact on the patient management.

Methods: Retrospective analysis of prospectively collected data of 1225 consecutive patients who underwent laparoscopic Roux-en-Y gastric bypass (n = 834) or sleeve gastrectomy (n = 391) at our institution. Read More

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http://dx.doi.org/10.1016/j.soard.2018.01.009DOI Listing
May 2018
15 Reads

Gastrothorax: A case of mistaken identity.

Int J Surg Case Rep 2018 17;44:66-69. Epub 2018 Feb 17.

Upper Gastrointestinal and Hepatobiliary Surgical Unit, Monash Health, 246 Clayton Road, Victoria 3168, Australia.

Introduction: Acute wrap failure post fundoplication is a rare but recognized complication and can be due to patient factors, disease factors and surgical factors. Herniation of the stomach into the thorax can mimic a pneumothorax clinically and radiologically and thus lead to bad outcomes for patients.

Presentation Of Case: We report the case of a 20-year-old male who presented to the emergency department with progressively worsening upper abdominal pain, nausea and vomiting followed by acute onset dyspnoea, six days post a laparoscopic repair of a small hiatus hernia and a Nissen fundoplication. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835008PMC
February 2018
1 Read

Streptococcus agalactiae meningoencephalitis associated with gastroesophageal reflux disease and chronic proton pump inhibitors use, in a 9 month-old infant: a case report.

BMC Pediatr 2018 02 1;18(1):21. Epub 2018 Feb 1.

Lucian Blaga University of Sibiu, Faculty of Medicine; "FOISOR" Clinical Hospital of Orthopedics, Traumatology and Osteoarticular TB Bucharest, Sibiu, Romania.

Background: Streptococcus agalactiae (Group B Streptococcus) is recognized as the etiologic agent of newborn and infant meningitis, aged up to 90 days, starting from the colonization of the maternal genital or gastrointestinal tract, but it is rarely responsible for meningitis in old infants.

Case Presentation: We present the case of a 9 month-old infant diagnosed with S. agalactiae meningoencephalitis associated with chronic gastroesophageal reflux disease treated with a proton pump inhibitor (PPI). Read More

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http://dx.doi.org/10.1186/s12887-018-0995-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796439PMC
February 2018

Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease.

Scand J Gastroenterol 2018 Mar 25;53(3):260-264. Epub 2018 Jan 25.

a Section of Digestive Diseases , Yale School of Medicine , New Haven , CT , USA.

Objectives: We assessed the performance characteristics of image-enhanced endoscopy with i-Scan or narrow band imaging (NBI) in patients with non-erosive gastroesophageal reflux disease (GERD) compared to controls without heartburn.

Material And Methods: Image-enhanced endoscopic findings of vascularity at the squamocolumnar junction, distal esophageal micro-erosions, and non-round pit pattern at the squamocolumnar junction were assessed in cases (heartburn not responsive to PPIs, positive results on validated GERD questionnaire, no esophageal erosions, esophageal biopsies with histologic evidence of GERD (basal cell hyperplasia, elongation of papillae and dilation of intercellular spaces all required)) and in controls (no GERD symptoms or esophageal erosions).

Results: Twenty cases and 60 controls were compared. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2018.1
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http://dx.doi.org/10.1080/00365521.2018.1430847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080852PMC
March 2018
3 Reads

Update on Functional Heartburn.

Gastroenterol Hepatol (N Y) 2017 Dec;13(12):725-734

Dr Yamasaki is a research fellow at the Esophageal and Swallowing Center at MetroHealth Medical Center in Cleveland, Ohio and a visiting scholar at Case Western Reserve University in Cleveland, Ohio. Ms O'Neil is a medical student at Case Western Reserve University. Dr Fass is the medical director of the Digestive Health Center, director of the Division of Gastroenterology and Hepatology, and head of the Esophageal and Swallowing Center at MetroHealth Medical Center, as well as a professor of medicine at Case Western Reserve University.

The definition of functional heartburn has been refined over the years. It is currently described, based upon Rome IV criteria, as typical heartburn symptoms in the presence of normal upper endoscopy findings (including normal biopsies), normal esophageal pH testing, and a negative association between symptoms and reflux events. Functional heartburn is very common, affecting women more than men, and with reflux hypersensitivity makes up the majority of heartburn patients who fail twice-daily proton pump inhibitor therapy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763558PMC
December 2017
11 Reads

The role of pepsin in the laryngopharyngeal reflux.

Otolaryngol Pol 2017 Dec;71(6):7-13

Department of Otolaryngology, Division of Medicine and Dentistry, Medical University of Warsaw, Poland.

Laryngopharyngeal reflux (LPR) is a common defect among laryngological and phoniatric patients. Although LPR is categorized as a superficial gastroesophageal reflux disease (GERD), differential diagnosis should treat these two diseases separately. LPR symptoms can be assessed in the interview using as a tool the reflux symptom index (RSI). Read More

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http://dx.doi.org/10.5604/01.3001.0010.7194DOI Listing
December 2017
6 Reads

Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: a case report with microbiological analysis.

BMC Infect Dis 2018 01 2;18(1). Epub 2018 Jan 2.

Center for Infectious Diseases and Infection Control, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan.

Background: Presence of Mycobacterium fortuitum in respiratory tracts usually indicates mere colonization or transient infection, whereas true pulmonary infection occurs in patients with gastroesophageal disease. However, little is known about the diagnostic indications for true M. fortuitum pulmonary infection and the natural history of the disease. Read More

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http://dx.doi.org/10.1186/s12879-017-2892-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748953PMC
January 2018
13 Reads

Feasibility of free-breathing dynamic contrast-enhanced MRI of gastric cancer using a golden-angle radial stack-of-stars VIBE sequence: comparison with the conventional contrast-enhanced breath-hold 3D VIBE sequence.

Eur Radiol 2018 May 19;28(5):1891-1899. Epub 2017 Dec 19.

Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.

Objectives: To investigate the feasibility and diagnostic value of free-breathing, radial, stack-of-stars three-dimensional (3D) gradient echo (GRE) sequence ("golden angle") on dynamic contrast-enhanced (DCE) MRI of gastric cancer.

Methods: Forty-three gastric cancer patients were divided into cooperative and uncooperative groups. Respiratory fluctuation was observed using an abdominal respiratory gating sensor. Read More

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http://dx.doi.org/10.1007/s00330-017-5193-1DOI Listing
May 2018
19 Reads

[Importance of functional diagnostics in gastroenterology].

Internist (Berl) 2018 01;59(1):25-37

Klinik und Poliklinik für Gastroenterologie und Rheumatologie, Department für Innere Medizin, Neurologie und Dermatologie, Universitätsklinikum Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland.

In this review article important and frequently used investigation methods for gastrointestinal functional diagnostics are presented. Some other rarely used special investigations are also explained. The hydrogen breath test is simple to carry out, ubiquitously available and enables the detection of lactose, fructose and sorbitol malabsorption. Read More

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http://link.springer.com/10.1007/s00108-017-0359-0
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http://dx.doi.org/10.1007/s00108-017-0359-0DOI Listing
January 2018
8 Reads

iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice.

Mucosal Immunol 2018 05 6;11(3):774-784. Epub 2017 Dec 6.

Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.

The intestinal epithelial cells constitute the first line of defense against gut microbes, which includes secretion of various antimicrobial substances. Reactive oxygen species (ROS) are well characterized as part of the innate phagocytic immunity; however, a role in controlling microorganisms in the gut lumen is less clear. Here, we show a role for nitric oxide synthase (iNOS)- and NOX1-produced ROS in maintaining homeostasis of the gut microbiota. Read More

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http://dx.doi.org/10.1038/mi.2017.106DOI Listing

Telomere length of gallbladder epithelium is shortened in patients with congenital biliary dilatation: measurement by quantitative fluorescence in situ hybridization.

J Gastroenterol 2018 Feb 15;53(2):291-301. Epub 2017 Nov 15.

Research Team for Geriatric Pathology and Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.

Background: Congenital biliary dilatation (CBD) is a congenital malformation involving both dilatation of the extrahepatic bile duct and pancreaticobiliary maljunction. Persistent reflux of pancreatic juice injures the biliary tract mucosa, resulting in chronic inflammation and higher rates of carcinogenesis in the biliary tract, including the gallbladder. Telomeres are repetitive DNA sequences located at the ends of chromosomes. Read More

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http://dx.doi.org/10.1007/s00535-017-1411-5DOI Listing
February 2018
13 Reads

GERD after per-oral endoscopic myotomy as compared with Heller's myotomy with fundoplication: a systematic review with meta-analysis.

Gastrointest Endosc 2018 Apr 2;87(4):934-943.e18. Epub 2017 Nov 2.

Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy.

Background And Aims: Per-oral endoscopic myotomy (POEM) represents a less invasive alternative to conventional laparoscopic Heller's myotomy (LHM) for patients with achalasia. It cannot be excluded, however, that the lack of fundoplication after POEM may result in a higher incidence of reflux disease, as compared with LHM. The aim of our study was to conduct a systematic review of prospective studies reporting the incidence of reflux disease developed after POEM and LHM. Read More

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http://dx.doi.org/10.1016/j.gie.2017.10.022DOI Listing
April 2018
25 Reads

Esophageal smooth muscle hypertrophy causing regurgitation in a rabbit.

J Vet Med Sci 2017 Nov 2;79(11):1848-1852. Epub 2017 Oct 2.

Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Drive, Madison, WI, 53706, U.S.A.

A five-year-old rabbit was evaluated for a 7 to 8 month history of regurgitation, weight loss, and hyporexia. Previously performed whole body radiographs, plasma biochemistry results and complete blood count revealed had no significant abnormalities. A computed tomography (CT) scan revealed a circumferential caudal esophageal thickening. Read More

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http://dx.doi.org/10.1292/jvms.17-0296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709563PMC
November 2017
1 Read

Documenting the prevalence of hiatal hernia and oesophageal abnormalities in brachycephalic dogs using fluoroscopy.

J Small Anim Pract 2017 Dec 30;58(12):703-708. Epub 2017 Sep 30.

Veterinary Sciences, University of Bristol, School of Veterinary Sciences, Langford, Bristol, BS40 5DU, UK.

Objectives: To report the prevalence of abnormal fluoroscopic findings in brachycephalic dogs that were presented to a referral hospital for obstructive airway syndrome.

Methods: Hospital records between May 2013 and November 2015 identified 36 brachycephalic dogs investigated for obstructive airway disease: 21 French bulldogs, six bulldogs, four Boston terriers, two pugs, two boxers and one shih-tzu. The presence or absence of hiatal hernia, delayed oesophageal transit, gastro-oesophageal reflux and redundant oesophagus were recorded. Read More

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http://doi.wiley.com/10.1111/jsap.12734
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http://dx.doi.org/10.1111/jsap.12734DOI Listing
December 2017
2 Reads

LOW PREVALENCE OF BARRETT'S ESOPHAGUS IN A RISK AREA FOR ESOPHAGEAL CANCER IN SOUTH OF BRAZIL.

Arq Gastroenterol 2017 Dec 21;54(4):305-307. Epub 2017 Sep 21.

Serviço de Gastroenterologia, Hospital Universitário, Universidade Federal de Santa Maria, RS, Brazil.

Background: Barrett's esophagus a complication of gastroesophageal reflux disease (GERD) is a precursor of esophageal adenocarcinoma. The incidence of esophageal adenocarcinoma has been increasing in most Western countries. Rio Grande do Sul (RS), the Southernmost state of Brazil has the highest rates of esophageal cancer with low prevalence of esophageal adenocarcinoma. Read More

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http://dx.doi.org/10.1590/S0004-2803.201700000-45DOI Listing
December 2017
11 Reads

Management of recurrent tracheoesophageal fistula after esophageal atresia and follow-up.

Dis Esophagus 2017 Sep;30(9):1-8

Department of Pediatric Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.

Recurrent tracheoesophageal fistula (rTEF) is a complex complication after the repair of esophageal atresia (EA) and remains a challenge because of difficulties in preoperative management and the substantial rates of mortality and morbidity after reoperation. By reviewing a single institution's experience in the management of rTEF and assessing the outcome, we aimed to provide an optimal approach for managing rTEF and to evaluate growth and feeding problems after reoperations. The medical records of 35 patients with rTEF treated at a single institution from June 2012 to December 2015 were reviewed, and follow-up data were collected from all survivors. Read More

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http://dx.doi.org/10.1093/dote/dox081DOI Listing
September 2017
29 Reads

Gastrointestinal Manifestations of STAT3-Deficient Hyper-IgE Syndrome.

J Clin Immunol 2017 Oct 13;37(7):695-700. Epub 2017 Aug 13.

Liver Diseases Branch, NIDDK, NIH, 10 Center Drive, Bldg 10, Bethesda, MD, 20892, USA.

Objective: STAT 3 deficiency (autosomal dominant hyper immunoglobulin E syndrome (AD-HIES)) is a primary immunodeficiency disorder with multi-organ involvement caused by dominant negative signal transducer and activator of transcription gene 3 (STAT3) mutations. We sought to describe the gastrointestinal (GI) manifestations of this disease.

Methods: Seventy subjects aged five to 60 years with a molecular diagnosis of AD-HIES were evaluated at the National Institutes of Health (NIH). Read More

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http://link.springer.com/10.1007/s10875-017-0429-z
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http://dx.doi.org/10.1007/s10875-017-0429-zDOI Listing
October 2017
35 Reads

Gallbladder mucosal lesions associated with high biliary amylase irrespective of pancreaticobiliary maljunction.

ANZ J Surg 2018 Jun 7;88(6):E517-E521. Epub 2017 Aug 7.

Upper Gastrointestinal Surgical Unit, Royal North Shore Hospital and North Shore Private Hospital, The University of Sydney, Sydney, New South Wales, Australia.

Background: Previous studies have focused on the presence of reflux in selected cohorts with pancreaticobiliary maljunction (PBM), but little is known regarding the wider incidence of occult reflux and associated mucosal changes. We aimed to correlate gallbladder mucosal abnormalities with objective evidence of PBM and occult pancreaticobiliary reflux (PBR) in an Australian population undergoing cholecystectomy.

Methods: Patients undergoing cholecystectomy between September 2010 and September 2012 were eligible for inclusion. Read More

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http://dx.doi.org/10.1111/ans.14136DOI Listing
June 2018
12 Reads

Long-term functional outcome after untethering surgery for a tethered spinal cord in patients with anorectal malformations.

Pediatr Surg Int 2017 Sep 4;33(9):995-999. Epub 2017 Aug 4.

Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Edobashi 2-174, Tsu, Mie, 514-8507, Japan.

Background: Anorectal malformation (ARM) is associated with a tethered spinal cord (TSC). Long-term functional outcome of untethering surgery for TSC in patients with ARM has not been well evaluated.

Methods: Patients aged 7 years and older who underwent repair of ARM and spinal magnetic resonance imaging from January 1995 to December 2008 were reviewed retrospectively. Read More

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http://dx.doi.org/10.1007/s00383-017-4127-yDOI Listing
September 2017
23 Reads

Successful laparoscopic treatment of advanced rectal cancer in an extremely elderly man (101 years and 9 months).

Asian J Endosc Surg 2018 Feb 13;11(1):50-52. Epub 2017 Jul 13.

Department of Internal Medicine, Medical Corporation for Saving Your Life (McSYL) Tatsumi Clinic and Hospital, Ikeda, Japan.

An extremely elderly man (age, 101 years and 9 months) visited our hospital because of recurrent and worsening anal bleeding. Type 2 rectal cancer was found in his rectum during colonoscopy. He did not have any severe coexisting diseases and had not suffered any episodes of dementia. Read More

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http://dx.doi.org/10.1111/ases.12406DOI Listing
February 2018
17 Reads

Efficacy of peroral endoscopic myotomy compared with other invasive treatment options for the different esophageal motor disorders.

Rev Esp Enferm Dig 2017 08;109(8):578-586

Aparato Digestivo, Complejo Hospitalario de Navarra, España.

Introduction: Peroral endoscopic myotomy (POEM) has been performed since 2008 on more than 5,000 patients. It has proven to be highly effective in the treatment of achalasia and has shown promising outcomes for other esophageal motility spastic disorders.

Methods: A literature review of the efficacy of POEM compared to the previous invasive treatments for different esophageal motility disorders was performed. Read More

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https://online.reed.es/fichaArticulo.aspx?iarf=683761742231-
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http://dx.doi.org/10.17235/reed.2017.4773/2016DOI Listing
August 2017
12 Reads