814 results match your criteria Gastrointestinal Reflux Imaging


Perforation of gastric volvulus within a giant hiatus hernia secondary to alendronate: A rare complication of bisphosphonate use.

Int J Surg Case Rep 2020 Jun 20;73:5-8. Epub 2020 Jun 20.

Department of Surgery, Redcliffe Hospital, Anzac Avenue, Redcliffe, QLD, Australia.

Introduction: Bisphosphonates are commonly used in the treatment of metabolic bone disease. However, they are associated with gastrointestinal side effects including acid reflux, mucosal erosion, and oesophageal stricture. We present a rare case of alendronate causing perforated gastric volvulus in a patient with giant hiatus hernia. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.06.068DOI Listing

Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system.

Surg Endosc 2020 Jun 16. Epub 2020 Jun 16.

Department of Surgery, Northshore University HealthSystem, GCSI Suite B665, 2650 Ridge Ave, Evanston, IL, 60201, USA.

Introduction: The Endoluminal Functional Lumen Imaging Probe (Endoflip™) is a balloon-based catheter that provides real-time, objective feedback regarding the distensibility of any sphincter in the gastrointestinal tract. Usage of the Functional Lumen Imaging Probe (FLIP) has not been standardized, which has limited the interpretation and generalizability of published data. The purpose of this consensus statement is to provide a standardized protocol for obtaining FLIP measurements in order to create a more uniform approach to data collection. Read More

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http://dx.doi.org/10.1007/s00464-020-07704-3DOI Listing

[Abdominal imaging in cystic fibrosis].

Radiologe 2020 Jun 3. Epub 2020 Jun 3.

Arbeitsbereich Kinderradiologie, Institut für Diagnostische und Interventionelle Radiologie, Medizinische Hochschule Hannover, Hannover, Deutschland.

Clinical Issue: Abdominal complications are often the first indications for cystic fibrosis (CF), a multiorgan disease. A broad range of abdominal manifestations are associated with the disease, including gastrointestinal abnormalities (such as meconium ileus in newborns and distal intestinal obstruction syndrome in older children) and hepatobiliary alterations (e.g. Read More

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http://dx.doi.org/10.1007/s00117-020-00703-4DOI Listing

Prevalence and Predictors of Gastrointestinal Dysmotility in Patients with Hypermobile Ehlers-Danlos Syndrome: A Tertiary Care Center Experience.

Cureus 2020 Apr 29;12(4):e7881. Epub 2020 Apr 29.

Gastroenterology, Cleveland Clinic Florida, Weston, USA.

Introduction Ehlers-Danlos syndrome (EDS), specifically the hypermobility type (hEDS), is associated with a variety of gastrointestinal (GI) conditions. This study aims to evaluate the prevalence of and factors associated with gut dysmotility in patients with hEDS. Methods This is a retrospective study of hEDS patients conducted at the Cleveland Clinic's Center for Personalized Genetic Healthcare between January 2007 and December 2017. Read More

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http://dx.doi.org/10.7759/cureus.7881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255528PMC

Ulcerative reflux esophagitis associated with Clostridium ventriculi following hiatoplasty - is antibiotic treatment necessary? A case report.

Z Gastroenterol 2020 May 11;58(5):456-460. Epub 2020 May 11.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.

Clostridium (C.) ventriculi (known as Sarcina ventriculi) is a ubiquitous gram-positive, anaerobic, acidophilic coccus found in patients with gastric motility disorders. The microorganisms can be identified histologically by their characteristic presentation in tetrads or packets of 8 in hematoxylin and eosin stains. Read More

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http://dx.doi.org/10.1055/a-1123-7984DOI Listing

Comparative quantitative survey of patient experience in Barrett's oesophagus and other gastrointestinal disorders.

BMJ Open Gastroenterol 2020 31;7(1):e000357. Epub 2020 Mar 31.

Division of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester and Manchester Academic Health Sciences Centre, Manchester, UK.

Objective: To assess health-related quality of life in patients with non-dysplastic Barrett's oesophagus (NDBO) and endoscopically treated dysplastic Barrett's oesophagus (DBO).

Design: This quantitative, self-administered questionnaire study was conducted across three National Health Service hospitals. Data were collected from three other cohorts; gastro-oesophageal reflux disease (GORD), colonic polyp surveillance and healthy individuals. Read More

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http://dx.doi.org/10.1136/bmjgast-2019-000357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170407PMC

Evaluation of upper endoscopic findings in patients with restless legs syndrome and gastric complaints.

Arq Neuropsiquiatr 2020 Apr;78(4):217-223

Uşak Univerrity School of Medicine, Department of Internal Medicine, Uşak, Turkey.

Background: The effect of gastrointestinal system disorders on Restless Legs Syndrome/Willis-Ekbom disease (RLS/WED) has been previously demonstrated by using serological tests. However, this association has not been supported by histopathological studies so far.

Objective: To investigate the relationship between RLS/WED, upper endoscopic imaging and histopathological results in patients diagnosed with RLS who underwent endoscopy because of gastrointestinal system (GIS) complaints. Read More

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http://dx.doi.org/10.1590/0004-282X20190192DOI Listing

Laparoscopic repair of complete intrathoracic stomach with iron deficiency anemia: A case report.

World J Clin Cases 2020 Mar;8(6):1180-1187

Department of Minimally Invasive Surgery, Hernia and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang Uygur Autonomous Region, China.

Background: Giant paraesophageal hiatal hernias (HH) are very infrequent, and their spectrum of clinical manifestations is large. Giant HH mainly occurs in elderly patients, and its relationship with anemia has been reported. For the surgical treatment of large HH, Nissen fundoplication is the most common antireflux procedure, and the reinforcement of HH repair with a patch (either synthetic or biologic) is still debatable. Read More

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http://dx.doi.org/10.12998/wjcc.v8.i6.1180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103977PMC

Two cases of agenesis of the dorsal pancreas and a review of the literature.

BMC Gastroenterol 2020 Apr 6;20(1):94. Epub 2020 Apr 6.

Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, 100053, China.

Background: Agenesis of the dorsal pancreas (ADP) is a very rare disease with no specific symptoms, and the pathogenesis is not clear. Some patients will be accompanied by other diseases, such as pancreatic tumor or pancreatitis. But most cases are very atypical and difficult to distinguish. Read More

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http://dx.doi.org/10.1186/s12876-020-01245-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137410PMC

A Comparison of the Relative Safety and Efficacy of Laparoscopic Choledochotomy with Primary Closure and Endoscopic Treatment for Bile Duct Stones in Patients with Cholelithiasis.

J Laparoendosc Adv Surg Tech A 2020 Feb 26. Epub 2020 Feb 26.

Department of General Surgery, The Second Affiliated Hospital of Shanxi Medical University, Taiyuan, China.

To date, several clinical trials have demonstated that both one-stage laparoscopic cholecystectomy (LC) combined with common bile duct exploration (LC+BDE) with primary closure and one-stage LC combined with endoscopic stone extraction (LC+ESE) are the two primary clinical approaches to treat cholelithiasis. However, no studies to date have directly compared the LC+BDE with primary closure and one-stage LC+ESE procedures. We, therefore, conducted a retrospective analysis of patients with cholelithiasis who had been treated through LC+ESE or LC+BDE to compare these two approaches for the treatment of cholecystitis and common bile duct stones (CCBDS). Read More

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http://dx.doi.org/10.1089/lap.2019.0775DOI Listing
February 2020

Late-term hiatal hernia after gastric bypass: an emerging problem.

Surg Obes Relat Dis 2020 Apr 25;16(4):471-475. Epub 2020 Jan 25.

Department of Surgery, Texas Tech University Health Sciences Center Paul Foster School of Medicine, El Paso, Texas.

Background: Gastric bypasses were the most common bariatric surgery for many years, and long-term complications after gastric bypass are known to be relatively common. Symptomatic hiatal hernia (HH) with pouch migration is a less-known complication. However, when these are symptomatic, they require surgical repair. Read More

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http://dx.doi.org/10.1016/j.soard.2020.01.018DOI Listing

Real-time MRI for dynamic assessment of gastroesophageal reflux disease: Comparison to pH-metry and impedance.

Eur J Radiol 2020 Apr 29;125:108856. Epub 2020 Jan 29.

Department of Diagnostic and Interventional Radiology, University Medical Center, Göttingen, 37075, Germany.

Purpose: To evaluate the diagnostic potential of real-time MRI for dynamic assessment of gastroesophageal reflux in patients with GERD (gastroesophageal reflux disease)-like symptoms compared to pH-metry and impedance.

Methods: Patients who underwent real-time MRI and pH-metry between 2015-2018 were included in this retrospective study. Real-time MRI at 3 T was achieved by undersampled radial FLASH acquisitions with iterative image reconstruction by NLINV. Read More

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http://dx.doi.org/10.1016/j.ejrad.2020.108856DOI Listing
April 2020
2.369 Impact Factor

The Wide-Ranging Spectrum of Cough-Induced Complications and Patient Harm.

Authors:
Ami Schattner

Am J Med 2020 05 31;133(5):544-551. Epub 2020 Jan 31.

The Faculty of Medicine, Hebrew University and Hadassah Medical School, Jerusalem, Israel. Electronic address:

Cough is one of the most common complaints encountered in every setting; however, complications associated with coughing have received relatively little attention. An exhaustive systematic review of the English literature revealed an exceedingly large and varied spectrum of cough-induced complications affecting many systems, including upper airways, chest wall and thorax, abdominal wall, heart and aorta, central nervous system, eye, gastrointestinal tract, urogenital system, and emotional and psychological harm. Prospective studies and prevalence data are conspicuously missing. Read More

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http://dx.doi.org/10.1016/j.amjmed.2019.12.044DOI Listing

Management of afferent loop syndrome after Roux-en-Y subtotal gastrectomy and choledocolithiasis with recurrent cholangitis.

BMJ Case Rep 2020 Jan 5;13(1). Epub 2020 Jan 5.

General Surgery, Hospital and University Centre of Coimbra, Coimbra, Portugal.

Afferent loop syndrome is a rare complication after gastrectomy with Billroth II or Roux-en-Y reconstruction, caused by an obstruction in the proximal loop. The biliary stasis and bacterial overgrowth secondary to this obstruction can lead to repeated episodes of acute cholangitis. We present the case of a male patient who had previously undergone gastrectomy with Roux-en-Y reconstruction and later experienced multiple episodes of acute cholangitis secondary to choledocolithiasis. Read More

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http://dx.doi.org/10.1136/bcr-2019-232498DOI Listing
January 2020

Chronic unexplained nausea in adults: Prevalence, impact on quality of life, and underlying organic diseases in a cohort of 5096 subjects comprehensively investigated.

PLoS One 2019 19;14(12):e0225364. Epub 2019 Dec 19.

Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.

We evaluated to define the clinically significant chronic nausea in general population and to assess the prevalence of chronic unexplained nausea after exclusion of organic causes through the meticulous medical examination. Two phase studies were conducted. In phase 1, telephone survey was conducted to define the clinically significant nausea in 5000 representative subjects for a general population. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225364PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922349PMC

Bile Reflux is a Common Finding in the Gastric Pouch After One Anastomosis Gastric Bypass.

Obes Surg 2020 Mar;30(3):875-881

Department of Gastrointestinal Surgery, Helsinki University Hospital, Abdominal Center, Haartmaninkatu 4, 00029 HUS, Helsinki, Finland.

Introduction: Data on postoperative bile reflux after one anastomosis gastric bypass (OAGB) is lacking. Bile reflux scintigraphy (BRS) has been shown to be a reliable non-invasive tool to assess bile reflux after OAGB. We set out to study bile reflux after OAGB with BRS and endoscopy in a prospective series (RYSA Trial). Read More

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http://dx.doi.org/10.1007/s11695-019-04353-xDOI Listing

Approaches and Challenges to Management of Pediatric and Adult Patients With Eosinophilic Esophagitis.

Gastroenterology 2020 03 10;158(4):840-851. Epub 2019 Dec 10.

Digestive Health Institute, Children's Hospital Colorado, Gastrointestinal Eosinophilic Diseases Program, University of Colorado School of Medicine, Aurora, Colorado.

Treatment of eosinophilic esophagitis has progressed from elemental formula for children and esophageal dilation for adults to selective exclusion of food triggers and swallowed topical corticosteroids. Management guidelines are available from the American Gastroenterological Association and the Joint Task Force on Allergy Immunology Practice Parameters. We cannot, however, evaluate the efficacy of treatments without a definition of response. Read More

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http://dx.doi.org/10.1053/j.gastro.2019.09.052DOI Listing

The Effect of Primary Duodenogastric Bile Reflux on the Presence and Density of and on Gastritis in Childhood.

Medicina (Kaunas) 2019 Dec 5;55(12). Epub 2019 Dec 5.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Van Education and Research Hospital, 65300 Van, Turkey.

Although there are many studies that investigate the relationship between duodenogastric reflux (DGR) and in adult patients, the reported data are contradictory. In addition, there are very few studies in the literature investigating the relationship between DGR and in the pediatric age group. In the present study, we investigated the effect of primary DGR on and gastritis. Read More

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http://dx.doi.org/10.3390/medicina55120775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956137PMC
December 2019

A Rare Case of Internal Gastroduodenal Hernia Through the Fundoplication Wrap Two Years Following Laparoscopic Nissen Fundoplication for the Treatment of Gastroesophageal Reflux Disease.

Am J Case Rep 2019 Dec 9;20:1837-1840. Epub 2019 Dec 9.

Department of Surgery, Centre Hospitalier Universitaire Ambroise Paré, Mons, Belgium.

BACKGROUND Gastroesophageal reflux disease (GERD) is a common condition that may be refractory to medical treatment with proton pump inhibitors (PPIs). Laparoscopic Nissen fundoplication is the recommended surgical treatment for GERD and is safe and effective. This report is of a rare case of internal gastroduodenal hernia as a late complication of laparoscopic Nissen fundoplication for the management of GERD in a 19-year-old woman. Read More

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http://dx.doi.org/10.12659/AJCR.917847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913275PMC
December 2019

The management of hiatal hernia: an update on diagnosis and treatment.

Med Pharm Rep 2019 Oct 25;92(4):321-325. Epub 2019 Oct 25.

2 Medical Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Background And Aim: Hiatal hernia (HH) occurs quite frequently in the general population and is characterized by a wide range of non-specific symptoms, most of them related to gastroesophageal reflux disease. Treatment can be challenging at times, depending on the existence of complications. The most recent guideline regarding the management of hiatal hernia was released by the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) in the year 2013. Read More

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http://dx.doi.org/10.15386/mpr-1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853045PMC
October 2019

From digital world to real life: a robotic approach to the esophagogastric junction with a 3D printed model.

BMC Surg 2019 Oct 25;19(1):153. Epub 2019 Oct 25.

Department of Medicine, Surgery and Neurosciences, Unit of General Surgery and Surgical Oncology, University of Siena, Strada delle Scotte, 4 - 53100, Siena, Italy.

Background: Three-dimensional (3D) printing may represent a useful tool to provide, in surgery, a good representation of surgical scenario before surgery, particularly in complex cases. Recently, such a technology has been utilized to plan operative interventions in spinal, neuronal, and cardiac surgeries, but few data are available in the literature about their role in the upper gastrointestinal surgery. The feasibility of this technology has been described in a single case of gastroesophageal reflux disease with complex anatomy due to a markedly tortuous descending aorta. Read More

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http://dx.doi.org/10.1186/s12893-019-0621-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814977PMC
October 2019

Esophageal Motor Dysfunctions in Gastroesophageal Reflux Disease and Therapeutic Perspectives.

J Neurogastroenterol Motil 2019 10;25(4):499-507

Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical Colleg e, Beijing, China.

Gastroesophageal reflux disease (GERD) is a very common disease, and the prevalence in the general population has recently increased. GERD is a chronic relapsing disease associated with motility disorders of the upper gastrointestinal tract. Several factors are implicated in GERD, including hypotensive lower esophageal sphincter, frequent transient lower esophageal sphincter relaxation, esophageal hypersensitivity, reduced resistance of the esophageal mucosa against the refluxed contents, ineffective esophageal motility, abnormal bolus transport, deficits initiating secondary peristalsis, abnormal response to multiple rapid swallowing, and hiatal hernia. Read More

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http://dx.doi.org/10.5056/jnm19081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786454PMC
October 2019
1 Read

Functional lumen imaging probe in gastrointestinal motility diseases.

J Dig Dis 2019 Nov 16;20(11):572-577. Epub 2019 Oct 16.

Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA, USA.

Dysfunction of gastrointestinal (GI) sphincters, including the lower esophageal sphincter (LES) at the esophagogastric junction (EGJ) and the pyloric sphincter, plays a vital role in GI motility disorders, such as achalasia, gastroesophageal reflux disease (GERD), gastroparesis, and fecal incontinence. Using multi-detector high-resolution impedance planimetry, the functional luminal imaging probe (FLIP) system measures simultaneous data on tissue distensibility and luminal geometry changes in the sphincter in a real-time manner. In this review we focus on the emerging data on FLIP, which can be used as an innovative diagnostic method during endoscopic or surgical procedures in GI motility disorders. Read More

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http://dx.doi.org/10.1111/1751-2980.12818DOI Listing
November 2019
7 Reads
1.924 Impact Factor

Aerodigestive disorders in dogs evaluated for cough using respiratory fluoroscopy and videofluoroscopic swallow studies.

Vet J 2019 Sep 27;251:105344. Epub 2019 Jul 27.

University of Missouri, College of Veterinary Medicine, Department of Veterinary Medicine and Surgery, 900 East Campus Drive, Columbia, MO 65211, USA. Electronic address:

Aerodigestive diseases, hybrid disorders representing a pathologic link between respiratory and alimentary tracts, may manifest with respiratory signs without gastrointestinal signs. These are underdiagnosed in dogs due to poor clinical recognition and diagnostic limitations. We hypothesize that a subset of dogs presenting for cough without gastrointestinal signs would have occult aerodigestive disorders identified using videofluoroscopic swallow study (VFSS). Read More

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http://dx.doi.org/10.1016/j.tvjl.2019.105344DOI Listing
September 2019
7 Reads

Multimodality imaging approach in a patient with Klippel-Trenaunay syndrome.

BMJ Case Rep 2019 Aug 20;12(8). Epub 2019 Aug 20.

Radiology, University of the Philippines Manila, Manila, Philippines.

Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder presenting with asymmetric limb hypertrophy, cutaneous capillary malformations and lower extremity varicosities. We discuss a 27-year-old man born with varicosities on both lower extremities, which progressively enlarged. Physical examination showed a grossly enlarged right hand. Read More

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http://dx.doi.org/10.1136/bcr-2018-228257DOI Listing
August 2019
1 Read

Prenatal Imaging Features and Postnatal Factors Associated with Gastrointestinal Morbidity in Congenital Diaphragmatic Hernia.

Fetal Diagn Ther 2020 21;47(4):252-260. Epub 2019 Aug 21.

Texas Children's Fetal Center, Texas Children's Hospital and the Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA,

Background: To perform a comprehensive assessment of postnatal gastrointestinal (GI) morbidity and determine the prenatal imaging features and postnatal factors associated with its development in patients with congenital diaphragmatic hernia (CDH).

Materials And Methods: A retrospective review was conducted of all infants evaluated for CDH at a quaternary fetal center from February 2004 to May 2017. Prenatal imaging features and postnatal variables were analyzed. Read More

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http://dx.doi.org/10.1159/000501555DOI Listing
August 2019
7 Reads
2.295 Impact Factor

How I Approach Dysphagia.

Curr Gastroenterol Rep 2019 Aug 20;21(10):49. Epub 2019 Aug 20.

Feinberg School of Medicine, Department of Medicine, Northwestern University, 676 St Clair St, 14th floor, Chicago, IL, 60611-2951, USA.

Purpose Of Review: This review presents an overview of the diagnostic approach to esophageal dysphagia and summarizes recent epidemiological trends and technical advancements.

Recent Findings: The evaluation of dysphagia begins with a detailed history followed by endoscopy to evaluate for any structural abnormalities including malignancy. This is especially true given the emergence of eosinophilic esophagitis (EoE) as a dominant cause of esophageal dysphagia. Read More

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http://dx.doi.org/10.1007/s11894-019-0718-1DOI Listing
August 2019
4 Reads

Misdiagnosis and pitfalls in Panayiotopoulos syndrome.

Epilepsy Behav 2019 09 29;98(Pt A):124-128. Epub 2019 Jul 29.

Child Neurology, NESMOS Department, Faculty of Medicine & Psychology, "Sapienza" University, c/o Sant'Andrea Hospital, Rome, Italy. Electronic address:

Panayiotopoulos syndrome (PS) is a frequent (6% among children of 1-15 years) and benign epileptic syndrome, characterized by predominantly autonomic symptoms (emesis, pallor, flushing, cyanosis, mydriasis/miosis, cardiorespiratory and thermoregulatory alterations, incontinence of urine and/or feces, hypersalivation, and modifications of intestinal motility) associated with simple motor focal seizures, which can be followed by secondary generalization. Panayiotopoulos syndrome can be extremely insidious, because it can mimic several condition, such as gastroenteritis, gastroesophageal reflux disease, encephalitis, syncope, migraine, sleep disorders, or even metabolic diseases. This peculiar pleiotropism should be kept in mind by child neurologists and pediatricians and general practitioners, because a wrong diagnosis may lead to inappropriate interventions. Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.07.016DOI Listing
September 2019
3 Reads

Heartburn and dyspepsia symptom severity improves after treatment and correlates with histology in adults with eosinophilic esophagitis.

Dis Esophagus 2019 Nov;32(9)

Center for Esophageal Diseases and Swallowing.

Non-dysphagia symptoms, such as heartburn and dyspepsia, are poorly characterized in adults with eosinophilic esophagitis (EoE). It is unclear if treatment improves these symptoms. The aim of this paper was to assess (i) heartburn and dyspepsia symptom severity in adult EoE patients using validated symptom measures; (ii) change in symptoms after treatment; and (iii) symptom association with endoscopic and histologic features. Read More

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http://dx.doi.org/10.1093/dote/doz028DOI Listing
November 2019
2 Reads

Adherence to clinical guidelines for Barrett's esophagus.

Scand J Gastroenterol 2019 Aug 17;54(8):945-952. Epub 2019 Jul 17.

Department of Molecular Medicine and Surgery, Upper Gastrointestinal Surgery, Karolinska Institutet, Karolinska University Hospital , Stockholm , Sweden.

Clinical guidelines recommend endoscopy surveillance at given intervals or endoscopic therapy for Barrett's esophagus with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). Whether these guidelines are followed in clinical practice is unknown and was assessed in this study. This nationwide Swedish cohort study included patients with Barrett's esophagus with histologically verified LGD or HGD from 50 centers in 2006-2013. Read More

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http://dx.doi.org/10.1080/00365521.2019.1641740DOI Listing
August 2019
5 Reads

First Report of Fatal Secondary Abdominal Compartment Syndrome Induced by Intestinal Gas Accumulation without Organic Occlusive Intestinal Lesion in a Child with Sepsis.

Am J Case Rep 2019 Jul 13;20:1011-1015. Epub 2019 Jul 13.

Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.

BACKGROUND Abdominal compartment syndrome (ACS), characterized by an increased intra-abdominal pressure and new-onset organ dysfunction, is a critical and potentially fatal condition, with no case of ACS caused by intestinal gas without intestinal lesion being reported to date. CASE REPORT A 2-year-old girl with a chromosomal abnormality of 1p36 deletion presented with fever and diarrhea following upper-gastrointestinal series for the evaluation of gastroesophageal reflux. After 20 days, she experienced septic shock and multiple-organ failure, accompanied with rapidly growing, severe abdominal distension. Read More

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http://dx.doi.org/10.12659/AJCR.915296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647614PMC
July 2019
15 Reads

Truncating ARL6IP1 variant as the genetic cause of fatal complicated hereditary spastic paraplegia.

BMC Med Genet 2019 07 4;20(1):119. Epub 2019 Jul 4.

Department of Genetics, Research Centre, King Faisal Specialist Hospital & Research Centre, MBC-03, P.O. Box 3354, Riyadh, 11211, Saudi Arabia.

Background: Mutations in ARL6IP1, which encodes a tetraspan membrane protein localized to the endoplasmic reticulum (ER), have been recently described in a large family with a complicated form of hereditary spastic paraplegia (HSP).

Case Presentation: We sought to expand the HSP phenotype associated with ARL6IP1 variants by examining a Saudi kindred with a clinically more severe presentation, which resulted in spontaneous neonatal death of both affected siblings. Clinical features encompassed not only spastic paraplegia but also developmental delay, microcephaly, cerebral atrophy, periventricular leukoencephalopathy, hypotonia, seizures, spasticity, jejunal stricture, gastrointestinal reflux, neuropathy, dysmorphism and respiratory distress. Read More

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http://dx.doi.org/10.1186/s12881-019-0851-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610916PMC
July 2019
4 Reads

Long-term (15-year) objective evaluation of 150 patients after laparoscopic Nissen fundoplication.

Surgery 2019 11 19;166(5):886-894. Epub 2019 Jun 19.

Department of Surgery, University Hospital, University of Chile, Santiago, Chile.

Introduction: Laparoscopic Nissen fundoplication is the preferred operative treatment for patients with gastroesophageal reflux disease. The most recent published results only refer to clinical evaluations and few discuss objective measurements. Our purpose was to determine the late results of laparoscopic Nissen fundoplication, performing clinical, endoscopic, histologic, and functional studies. Read More

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http://dx.doi.org/10.1016/j.surg.2019.04.024DOI Listing
November 2019
19 Reads

Hiatal hernias in patients with GERD-like symptoms: evaluation of dynamic real-time MRI vs endoscopy.

Eur Radiol 2019 Dec 11;29(12):6653-6661. Epub 2019 Jun 11.

Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.

Purpose: To assess the diagnostic potential of real-time MRI for assessment of hiatal hernias in patients with GERD-like symptoms compared to endoscopy.

Material And Methods: One hundred eight patients with GERD-like symptoms were included in this observational cohort study between 2015 and 2017. Real-time MRI was performed at 3. Read More

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http://dx.doi.org/10.1007/s00330-019-06284-8DOI Listing
December 2019
26 Reads

Modified Sleeve Gastrectomy Combined with Laparoscopic Rossetti Fundoplication and Vascularization Assessment with Indocyanine Green.

Obes Surg 2019 09;29(9):3086-3088

Department of Surgery, S.I.C.OB. (Italian Society of Bariatric Surgery) Referral Center for Bariatric Surgery, San Donato Group, Policlinico San Marco, 24040 Zingonia-Osio Sotto, Bergamo, Italy.

Aim: Morbid obesity is a key risk factor for gastroesophageal reflux; the aim of this study is to describe the technique of modified laparoscopic Rossetti fundoplication to treat morbid obesity related to GERD.

Methods: This is a video/dynamic manuscript on operative technique. We present the case of a 38-year-old patient referred to our institution for morbid obesity (BMI 43 kg/m2) related to GERD symptoms with grade A esophagitis at the preoperative upper gastro intestinal endoscopy and in daily therapy with PPI since years. Read More

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http://dx.doi.org/10.1007/s11695-019-03970-wDOI Listing
September 2019
3 Reads

Clinical outcomes of non-alcoholic fatty liver disease: Polish-case control study.

Adv Clin Exp Med 2019 Dec;28(12):1615-1620

Department of Gastroenterology and Hepatology, Wroclaw Medical University, Poland.

Background: Non-alcoholic fatty liver disease (NAFLD) is becoming the most common cause of chronic liver disease worldwide, affecting up to 30% of population. Non-alcoholic fatty liver disease can lead to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma. Age, obesity, insulin resistance, type 2 diabetes, and dyslipidemia are important risk factors for developing hepatic steatosis. Read More

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http://www.advances.umed.wroc.pl/ahead-of-print/106173.pdf
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http://dx.doi.org/10.17219/acem/106173DOI Listing
December 2019
14 Reads

Quantification of the source, amount and duration of aspiration in the lungs of infants using gamma scintigraphy.

Paediatr Respir Rev 2019 Nov 4;32:23-27. Epub 2019 Apr 4.

Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Background: Aspiration can cause acute symptoms and chronic lung disease in the developing lung. However, the source of aspiration in infants is often unclear, making the choice of intervention difficult.

Objective: To quantify the source, amount and duration of lung aspiration in infants using gamma scintigraphy. Read More

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http://dx.doi.org/10.1016/j.prrv.2019.03.006DOI Listing
November 2019
4 Reads

Oesophageal atresia.

Nat Rev Dis Primers 2019 04 18;5(1):26. Epub 2019 Apr 18.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Pediatric Gastroenterology and Nutrition, Amsterdam, The Netherlands.

Oesophageal atresia (EA) is a congenital abnormality of the oesophagus that is caused by incomplete embryonic compartmentalization of the foregut. EA commonly occurs with a tracheo-oesophageal fistula (TEF). Associated birth defects or anomalies, such as VACTERL association, trisomy 18 or 21 and CHARGE syndrome, occur in the majority of patients born with EA. Read More

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http://www.nature.com/articles/s41572-019-0077-0
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http://dx.doi.org/10.1038/s41572-019-0077-0DOI Listing
April 2019
28 Reads

The Rationale and Efficacy of Primary and Secondary Prevention in Adenocarcinomas of the Upper Gastrointestinal Tract.

Dig Dis 2019 10;37(5):381-393. Epub 2019 Apr 10.

Department of Gastroenterology, Hepatology and Infectious Disease, Otto-von-Guericke University, Magdeburg, Germany.

While the primary risk factor for oesophageal adenocarcinoma (OAC) and its precursor lesion Barrett's oesophagus (BO) is gastro-oesophageal reflux, the infection with Helicobacter pylori (H. pylori) is the dominant risk factor for gastric cancer. Reduction of reflux by dietary measures and proton pump inhibitors has some merits in OAC prevention, and the chemopreventive effect of Aspirin and statins is being widely investigated; however, improved outcome in OAC occurs primarily as the result of secondary prevention. Read More

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http://dx.doi.org/10.1159/000499706DOI Listing
July 2019
9 Reads

Barrett's Esophagus and Esophageal Carcinoma: Can Biomarkers Guide Clinical Practice?

Curr Gastroenterol Rep 2019 Mar 12;21(4):14. Epub 2019 Mar 12.

Department of Medicine and the Center for Esophageal Diseases, Baylor University Medical Center, Dallas, TX, 75246, USA.

Purpose Of Review: Despite gastrointestinal societal recommendations for endoscopic screening and surveillance of Barrett's esophagus, the rates of esophageal adenocarcinoma continue to rise. Furthermore, this current practice is costly to patients and the medical system without clear evidence of reduction in cancer mortality. The use of biomarkers to guide screening, surveillance, and treatment strategies might alleviate some of these issues. Read More

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http://dx.doi.org/10.1007/s11894-019-0685-6DOI Listing
March 2019
8 Reads

The identification and treatment of intestinal malrotation in older children.

Pediatr Surg Int 2019 Jun 27;35(6):665-671. Epub 2019 Feb 27.

Department of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas City, MO, 64108, USA.

Purpose: Intestinal malrotation is often diagnosed in infancy. The true incidence of malrotation outside of this age is unknown. These patients can present atypically or be asymptomatic and diagnosed incidentally. Read More

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http://dx.doi.org/10.1007/s00383-019-04454-9DOI Listing
June 2019
4 Reads

Real-time MRI for the dynamic assessment of fundoplication failure in patients with gastroesophageal reflux disease.

Eur Radiol 2019 Sep 25;29(9):4691-4698. Epub 2019 Feb 25.

Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, 37075, Göttingen, Germany.

Purpose: To assess the diagnostic potential of dynamic real-time MRI for fundoplication failure in patients with persistent or recurrent GERD-like (gastroesophageal reflux disease) complaints.

Material And Methods: Twenty-two consecutive patients (male n = 11; female n = 11; median age 59 years) with recurrent or persistent GERD-like symptom after fundoplication were enrolled between 2015 and 2017. Median duration of GERD-like symptoms was 21 months. Read More

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http://dx.doi.org/10.1007/s00330-019-06025-xDOI Listing
September 2019
10 Reads

Incidentally discovered intestinal nonrotation at time of bariatric surgery: Which operation to perform?

Surg Obes Relat Dis 2019 Mar 11;15(3):424-430. Epub 2019 Jan 11.

Department of Surgery, Queen's University, Kingston, Ontario, Canada. Electronic address:

Background: An incidental finding of intestinal nonrotation at the time of bariatric surgery poses the following 2 dilemmas: (1) which operation to perform, and (2) whether an appendectomy should be performed concurrently.

Objectives: To review the experience of 2 Bariatric Centers of Excellence with laparoscopic sleeve gastrectomy (LSG) in patients with intestinal nonrotation, and to perform a systematic review of the literature on this topic.

Setting: Two Bariatric Centers of Excellence as designated by the Ontario Bariatric Network. Read More

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http://dx.doi.org/10.1016/j.soard.2018.12.036DOI Listing
March 2019
7 Reads

New Developments in Esophageal Motility Testing.

Curr Treat Options Gastroenterol 2019 Mar;17(1):76-88

University of Colorado Reflux & Esophageal Diseases Center, Division of Gastroenterology & Hepatology, Department of Medicine, University of Colorado, Anschutz Medical Campus, Academic Office 1 Room 7605, 12631 E. 17th Ave, Aurora, CO, 80045, USA.

Purpose Of Review: The purpose of this review is to present the latest developments in esophageal motility testing and summarize the current paradigm of esophageal motility disorders.

Recent Findings: While high-resolution esophageal pressure topography interpreted according to the Chicago Classification represents the gold standard to evaluate esophageal motility, recent studies highlight the additional value of novel manometric applications. Novel applications include provocative measures to assess for obstructive physiology at the esophagogastric junction (EGJ), esophageal peristaltic reserve, and rumination and supragastric belching disorders. Read More

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http://link.springer.com/10.1007/s11938-019-00218-5
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http://dx.doi.org/10.1007/s11938-019-00218-5DOI Listing
March 2019
39 Reads

Predictors of Hiatal Hernia Recurrence After Laparoscopic Anti-reflux Surgery with Hiatal Hernia Repair: a Prospective Database Analysis.

J Gastrointest Surg 2019 04 7;23(4):696-701. Epub 2019 Jan 7.

Center for Advanced Surgical Technology, University of Nebraska Medical Center, 986246 Nebraska Medical Center, Omaha, NE, 68198-6246, USA.

Background: The aim of this study is to identify factors that can predict hiatal hernia recurrence (HHR) in patients after anti-reflux surgery with hiatal hernia (HH) repair.

Methods: A single-institution, prospectively collected database was reviewed (January 2002-October 2015) with inclusion criteria of GERD and laparoscopic anti-reflux (AR) surgery with HH repair. Demographics, esophageal symptom scores, and pre- and post-upper gastrointestinal imaging (UGI) were collected. Read More

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http://dx.doi.org/10.1007/s11605-018-04073-0DOI Listing
April 2019
12 Reads

Sugammadex Reversal of a Large Subcutaneous Depot of Rocuronium in a Dialysis Patient: A Case Report.

A A Pract 2019 May;12(10):375-377

From the Department of Anesthesiology, University of Minnesota, Minneapolis, Minnesota.

Sugammadex is a modified gamma cyclodextrin that encapsulates rocuronium. We report the successful use of sugammadex in the management of an elderly man with end-stage renal failure who sustained an infiltration of subcutaneous rocuronium during rapid sequence induction of general anesthesia. Given the erratic absorption of subcutaneous rocuronium from the tissue, sugammadex was chosen to reverse the neuromuscular block at the end of the procedure. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000934DOI Listing
May 2019
3 Reads

Primary gastric inflammatory myofibroblastic tumor: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13423

Department of Radiology, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, People's Republic of China.

Rationale: Primary gastric inflammatory myofibroblastic tumor is extremely rare. Only a few cases were reported in the domestic and foreign medical literature with corresponding imaging findings of this disease even more rarely reported.

Patient Concerns: We present one case of a 52-year-old female patient with upper abdominal pain, acid reflux, and belching for 2 months. Read More

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http://dx.doi.org/10.1097/MD.0000000000013423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320093PMC
December 2018
7 Reads
5.723 Impact Factor