Search Our Scientific Publications & Authors

Heart Vessels 2019 Apr 16. Epub 2019 Apr 16.

Department of Cardiovascular Medicine, JR Hiroshima Hospital, 3-1-36 Futabanosato, Higashi-ku, Hiroshima, 732-0057, Japan.

It is well known that patients with gastroesophageal reflux disease (GERD) experience GERD-related chest pain, but little is known about the relationship between GERD and coronary artery disease (CAD). We evaluated medical history of GERD in patients with suspected CAD and its association with types of CAD. We enrolled 236 patients who underwent coronary angiography (CAG). Read More

J Pediatr Gastroenterol Nutr 2019 Apr 9. Epub 2019 Apr 9.

Institute of Clinical Medicine, University of Oslo, Norway.

Objectives: Parents of children with a chronic illness are at risk for impaired psychosocial functioning. Gastroesophageal reflux disease (GERD) is such a disease, and no studies have investigated effects of antireflux surgery on parental psychological distress. The aims of this study were to assess psychological distress and state and trait anxiety in mothers of children with GERD, and to explore possible changes after antireflux surgery. Read More

J Family Med Prim Care 2019 Feb;8(2):462-467

College of Medicine, Jazan University, Jazan, Saudi Arabia.

Introduction: Gastroesophageal reflux disease (GERD) is one of the most common chronic gastrointestinal disorders in adults, it develops when the stomach contents reflux and rise up into the esophagus as a result from lower esophageal sphincter dysfunction. Stomach acid that touches the lining of the esophagus causes symptoms and complications. The classical symptoms of GERD include heartburn, usually after eating, chest pain, and regurgitation. Read More

Laryngoscope 2019 Apr 14. Epub 2019 Apr 14.

Research Committee of the Young Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS), Marseille, France.

Objectives/hypothesis: To develop and validate the Reflux Symptom Score (RSS), a self-administered patient-reported outcome questionnaire for patients with laryngopharyngeal reflux (LPR).

Study Design: Prospective controlled study.

Methods: A total of 113 patients with LPR were enrolled and treated with diet and 3 months of pantoprazole, alginate, and/or magaldrate depending on the LPR characteristics (acid, nonacid, or mixed). Read More

Zentralbl Chir 2019 Apr 12;144(2):171-178. Epub 2019 Apr 12.

Chirurgische Abteilung, Marienkrankenhaus Kassel, Deutschland.

There is renewed interested in novel surgical procedures for GERD, as there are potential undesirable effects of PPI therapy and the results of the current surgical methods are not always satisfactory. The technique and results of magnetic enhancement (LINX) and electrical stimulation (EndoStim) of the lower oesophageal sphincter are presented and discussed. Both methods are less invasive, principally reversible and associated with encouraging mid-term results. Read More

Zentralbl Chir 2019 Apr 12;144(2):163-170. Epub 2019 Apr 12.

Universitätsklinik für Chirurgie, Salzburger Landeskliniken, Salzburg, Österreich.

Treatment of primary idopathic achalasia, the most common of the rare oesophageal motility disorders, is currently changing. The therapeutic priciple of Heller's myotomy is increasingly accepted as standard. In 1913, the German surgeon Ernst Heller described the cardiomyotomy named after him, faciliating excellent symptom control. Read More

Endoscopy 2019 Apr 12. Epub 2019 Apr 12.

Department of Gastroenterology and Hepatology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, China.

J Pharm Policy Pract 2019 29;12. Epub 2019 Mar 29.

Institute of clinical sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT UK.

Background: Proton pump inhibitors (PPIs) are used worldwide for the treatment of gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD). Although considered to be widely safe, PPIs have been associated with the potential risk of adverse effects such as infections including pneumonia and , malabsorption of vitamins and minerals, dementia and more recently with chronic kidney disease (CKD). Evidence including large cohort studies suggests that there is a greater risk of developing CKD in chronic users of PPIs. Read More

Neurogastroenterol Motil 2019 Apr 11:e13584. Epub 2019 Apr 11.

Division of Gastroenterology, Stanford University, Stanford, California.

Background: Ineffective esophageal motility (IEM) is a heterogenous minor motility disorder diagnosed when ≥50% ineffective peristaltic sequences (distal contractile integral <450 mm Hg cm s) coexist with normal lower esophageal sphincter relaxation (integrated relaxation pressure < upper limit of normal) on esophageal high-resolution manometry (HRM). Ineffective esophageal motility is not consistently related to disease states or symptoms and may be seen in asymptomatic healthy individuals.

Purpose: A 1-day symposium of esophageal experts reviewed existing literature on IEM, and this review represents the conclusions from the symposium. Read More

JBI Database System Rev Implement Rep 2019 Apr;17(4):507-512

Texas Christian University, Fort Worth, USA.

Review Objective/question: The objective of this review is to determine which 270-degree fundoplication procedure has a better outcome in patients with chronic or refractory gastroesophageal reflux disease (GERD). This review will identify the fundoplication approach for chronic or refractory GERD that provides better reflux control with minimal post-procedure complications.The question of this review is: what is the effectiveness of transoral incisionless fundoplication compared to Toupet fundoplication in adult patients with chronic or refractory GERD? Read More

Medicines (Basel) 2019 Apr 9;6(2). Epub 2019 Apr 9.

Department of Food Science and Nutrition, University of the Aegean, Mitropoliti Ioakeim 2, 81400 Myrina, Limnos, Greece.

Epidemiological studies have suggested a possible correlation between nutritional factors and gastrointestinal diseases. A case⁻control study was designed in order to investigate if functional foods consumption and Mediterranean diet adherence have a positive effect in ulcerative colitis, Crohn's disease, irritable bowel syndrome, and gastroesophageal reflux disease. In total, 142 patients (cases) and 147 gender-matched healthy people (controls) participated in the study. Read More

Gut Liver 2019 Feb 27. Epub 2019 Feb 27.

Department of Internal Medicine, Gangnam Severance Hospital, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.

Background/aims: Bicarbonate-containing alginate formulations are reported to be effective for controlling reflux symptoms. However, the efficacy of Lamina G alginate without gas production has not been reported. The aim is to evaluate the efficacy of a non-bicarbonate alginate in individuals with reflux symptoms without reflux esophagitis. Read More

J Sleep Res 2019 Apr 10:e12852. Epub 2019 Apr 10.

School of Science and Engineering, Reykjavik University, Reykjavik, Iceland.

Many different subjective tools are being used to measure excessive daytime sleepiness (EDS) but the most widely used is the Epworth Sleepiness Scale (ESS). However, it is unclear if using the ESS is adequate on its own when assessing EDS. The aim of this study was to estimate the characteristics and prevalence of EDS using the ESS and the Basic Nordic Sleep Questionnaire (BNSQ) in general population samples. Read More

Z Gastroenterol 2019 Apr 9;57(4):491-496. Epub 2019 Apr 9.

Dept. of Internal Medicine, Bethlehem Health Center, Stolberg/Rhineland, Germany.

Background:  The influence of singing activities and breathing exercises on the presence of gastroesophageal reflux disease (GERD) symptoms is not clear. While an Austrian study found symptom reduction, an Italian study showed more symptoms in professional opera choristers. These contradictory results may be due to differential intensity of the singing exercises. Read More

Int J Environ Res Public Health 2019 Apr 6;16(7). Epub 2019 Apr 6.

Division of Pulmonary and Critical Care Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08901, USA.

World Trade Center (WTC) dust-exposed subjects have multiple comorbidities that affect sleep. These include obstructive sleep apnea (OSA), chronic rhinosinusitis (CRS), gastroesophageal-reflux disorder (GERD) and post-traumatic stress disorder (PTSD). We examined the impact of these conditions to sleep-related outcomes. Read More

Georgian Med News 2019 Feb(287):78-82

Kharkiv Medical Academy of Postgraduate Education, Department of Therapy, Rheumatology and Clinical Pharmacology, Ukraine.

The elderly patients problem is comorbidity - concurrent presence of different diseases. Coronary artery disease (CAD) and gastroesophageal reflux disease (GERD) are one of the most common diseases worldwide that in a considerable percentage of cases occur together. The aim of our study was to investigate features of endothelial dysfunction in old people with CAD and concomitant GERD. Read More

Georgian Med News 2019 Feb(287):7-12

Medistate Baskent University School of Medicine, Department of General Surgery.

The aim of this study is to evaluate outcomes of Nissen-Rossetti fundoplication in-terms of objective measures and quality of life evaluation instruments. For the period in observation, the chronic GERD patients, who had undergone LNRF surgery, were evaluated. The long-term outcome was assessed by subjectively comparing the preoperative and postoperative symptoms and Gastroesophageal reflux-Health related quality of life index. Read More

Surgery 2019 Apr 4. Epub 2019 Apr 4.

Department of Surgery, Anne Arundel Medical Center, Annapolis, MD.

Background: We present the largest single-center study to date of surgical and quality-of-life outcomes among patients treated with laparoscopic antireflux surgery for reflux-associated chronic cough. Extraesophageal manifestations of chronic gastroesophageal reflux are increasingly recognized, among which chronic cough may substantially compromise patient quality of life. Although the benefits of antireflux surgery are well documented in patients with typical symptoms of gastroesophageal reflux disease, less is known about the short-term impact of antireflux surgery on associated chronic cough. Read More

Pediatr Emerg Care 2019 Apr 3. Epub 2019 Apr 3.

Objective: A brief resolved unexplained event (BRUE) in infancy is a common reason for visiting the emergency department. However, little is known about the long-term outcomes of such an event. This study evaluates future mortality, morbidity, and/or developmental outcome after a BRUE. Read More

Gastroenterol Nurs 2019 Mar/Apr;42(2):E1

Gastroenterol Nurs 2019 Mar/Apr;42(2):185-188

Jayne Jennings Dunlap, DNP, APRN, FNP-C, is Assistant Clinical Professor, Nelda C. Stark College of Nursing, Texas Woman's University, Houston. Sheila Patterson, MSN, APRN, FNP-C, is Family Nurse Practitioner, Shannon Gastroenterology, San Angelo, Texas.

J Biol Regul Homeost Agents 2019 Mar-Apr,;33(2):593-599

Department of Translational Medical Sciences, Section of Pediatrics, Federico II University, Naples, Italy.

Gastroesophageal reflux disease (GERD) may be frequently associated with asthma in children and may affect asthma control. Proton pump inhibitors (PPI) are commonly prescribed in asthmatic children, despite uncertain efficacy on respiratory symptoms and risk of relevant adverse effects. Read More

Zhen Ci Yan Jiu 2019 Feb;44(2):140-3

School of Acupuncture-moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.

Objective: To observe the curative effect of acupuncture stimulation of the back segment (10 spots below the spinous processes from T3 to T12) of the Governor Vessel in the treatment of gastroesophageal reflux cough (GERC).

Methods: A total of 60 cases of GERC patients were randomly divided into acupuncture and medication groups (＝30 in each). For patients of the acupuncture group, the depression spots below the spinous processes from T3 to T12, including acupoints Shenzhu (GV12), Shendao (GV11), Lingtai (GV10), Zhiyang (GV9), Jinsuo (GV8) and non-acupoints (T4, T8, T12) were punctured with filiform needles, once every other day for 8 weeks. Read More

Obes Surg 2019 Apr 4. Epub 2019 Apr 4.

Department of Digestive, Oncologic and Bariatric Surgery, AP-HP, Hôpital Européen Georges Pompidou and Université Paris Descartes, 20 Rue Leblanc, 75015, Paris, France.

Introduction: One anastomosis gastric bypass (OAGB) was suggested as an option in the management of weight loss failure after sleeve gastrectomy (SG). In parallel, the length of the biliopancreatic limb (BPL) is currently debated.

Objectives: To evaluate morbidity and efficiency of the conversion of SG to OAGB using two lengths of BPL (150 cm versus 200 cm). Read More

Gastroenterol Res Pract 2019 3;2019:6271910. Epub 2019 Mar 3.

Department of Pediatric Allergy, Gastroenterology and Nutrition, Medical University of Lodz, Lodz, Poland.

Various clinical symptoms are attributed to extraesophageal reflux disease (EERD). Multichannel intraluminal impedance-pH monitoring (MII-pH) is considered to correlate symptoms with acid and nonacid gastroesophageal reflux (GER) events. Pharyngeal pH monitoring (Dx-pH) is considered to correlate the decrease in the pH level in the oropharynx with reported symptoms and to diagnose supraesophageal reflux. Read More

Gastroenterol Res Pract 2019 24;2019:3286738. Epub 2019 Feb 24.

Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.

Background: Both long-term proton pump inhibitor use and surgical fundoplication have potential drawbacks as treatments for chronic gastroesophageal reflux disease (GERD). Our aim was to investigate the potential efficacy of antireflux mucosectomy (ARMS) in porcine and determine the optimal circumference of resection in relation to gastroesophageal junction (GEJ).

Methods: Nine pigs were allocated into the following 3 groups by computerized randomization: group A: control, group B: 1/3 circumference of the esophagus, and group C: 2/3 circumference of the esophagus. Read More

Adv Clin Exp Med 2019 Mar;28(3):319-324

Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Poland.

Background: Chronic obstructive pulmonary disease (COPD) is associated with various comorbidities, which influence the course of COPD and worsen prognosis.

Objectives: The aim of this study was to analyze the comorbidities in a cohort of COPD patients in Poland during 12 months of observation.

Material And Methods: A total of 444 COPD patients (median age: 66. Read More

Zhongguo Zhen Jiu 2019 Mar;39(3):241-5

the First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China.

Objective: To evaluate the clinical efficacy of umbilical moxibustion in the treatment of patients with idiopathic pulmonary interstitial fibrosis complicated with gastroesophageal reflux of lung-spleen deficiency.

Methods: A total of 116 patients with idiopathic pulmonary fibrosis complicated with gastroesophageal reflux of lung spleen-deficiency were randomized into an observation group (58 cases) and a control group (58 cases). In the control group, the routine treatment was applied; in the observation group, on the base of the treatment as the control group, the umbilical moxibustion was used. Read More

J Gastrointest Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Biomedical Sciences for Health, Division of General Surgery, IRCCS Policlinico San Donato, University of Milan, Milan, Italy.

Objective: Minimally invasive enucleation is the treatment of choice in symptomatic patients with esophageal leiomyoma. Comprehensive long-term follow-up data are lacking. Aim of this study was to review the clinical outcomes of three procedures for enucleation of leiomyoma of the esophagus and esophagogastric junction. Read More

Can J Gastroenterol Hepatol 2019 3;2019:5036160. Epub 2019 Mar 3.

Division of Gastroenterology, Gastro-Intestinal Motility Center, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.

Background: Jackhammer esophagus is a hypercontractile esophageal disorder recently brought to light with the advent of high resolution manometry (HRM). As little is known about its clinical presentation, the aim of this study was to identify the clinical characteristics associated with this new gastrointestinal motility disorder.

Methods: A retrospective study was conducted on patients visiting the CHUM's Gastro-Intestinal Motility Center from January 2015 to December 2017. Read More

Praxis (Bern 1994) 2019 ;108(5):307-313

1 Klinik für Präventivzahnmedizin, Parodontologie und Kariologie, Zentrum für Zahnmedizin, Universität Zürich.

Tooth Erosions Associated with Gastroesophageal Reflux: Cause, Prevention and Restorative Therapy Abstract. Dental erosions are caused by the recurring contact of solutions which are unsaturated in tooth minerals,ith hard tooth substances. This initially leads to softening and later to an irreversible loss of hard tooth substance. Read More

Vestn Otorinolaringol 2019 ;84(1):68-71

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech, Ministry of Health of the Russian Federation, Saint-Petersburg, Russia, 190013.

Laryngitis is one of the commonest causes of dysphonia in the subjects engaged in the voice and speech professions. This condition can be either associated with the professional activities or related to voice fatigue. It is a common practice to distinguish between acute and chronic forms of occupational laryngitis. Read More

J Gastroenterol 2019 Apr 1. Epub 2019 Apr 1.

Division of Gastroenterology and Hepatology, Integrative Center of Internal Medicine, Gunma University Hospital, Maebashi, Japan.

Background: Esophageal motility abnormalities (EMAs) and interstitial lung diseases (ILDs) are often seen in patients with systemic sclerosis (SSc). Gastroesophageal reflux disease (GERD) could be associated with ILDs, but it is not fully understood if ILDs are caused by GERD or SSc itself.

Methods: A total of 109 patients with SSc who underwent high-resolution manometry were enrolled. Read More

Cureus 2019 Jan 16;11(1):e3895. Epub 2019 Jan 16.

Cardiology, West Virginia University, Morgantown, USA.

A 57-year-old male with gastroesophageal reflux disease and esophageal stricture with dilation presented as a cardiac catheterization lab activation for anterolateral ST-segment elevation myocardial infarction. He had suffered an unwitnessed syncopal episode after severe substernal chest pain. Electrocardiogram (ECG) showed anterolateral ST-segment elevation. Read More

Asthma Res Pract 2019 19;5. Epub 2019 Mar 19.

Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomédica Sant Pau, Carrer Mas Casanovas 90, 08041 Barcelona, Spain.

Background: The prevalence of chronic diseases in the elderly (> 65 years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65 years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma. Read More

Ther Adv Chronic Dis 2019 26;10:2040622319837851. Epub 2019 Mar 26.

Esophageal Center, Department of Gastroenterology and Hepatology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Barrett's esophagus is the precursor lesion for esophageal adenocarcinoma. Screening and surveillance of Barrett's esophagus are undertaken with the goal of earlier detection and lowering the mortality from esophageal adenocarcinoma. The widely used technique is standard esophagogastroduodenoscopy with biopsies per the Seattle protocol for screening and surveillance of Barrett's esophagus. Read More

Surg Obes Relat Dis 2019 Jan 25. Epub 2019 Jan 25.

Body Science & Metabolic Disorders International (BMI) Medical Center, China Medical University Hospital, Taichung City, Taiwan (ROC). Electronic address:

Background: Laparoscopic loop duodenojejunal bypass with sleeve gastrectomy (LDJB-SG) is a new metabolic procedure. Our initial data on type 2 diabetes (T2D) remission after LDJB-SG were promising.

Objectives: The aim of this study was to look at our intermediate outcomes after LDJB-SG. Read More

Esophagus 2019 Mar 29. Epub 2019 Mar 29.

Department of Gastroenterology, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Background: Esophageal eosinophilia (EE) is a basal condition of eosinophilic esophageal disorders including eosinophilic esophagitis (EoE) and asymptomatic EE. EoE is considered as an allergic disorder, while it is unclear whether other non-allergic conditions are involved in the pathophysiology of EE. The aim of this study is to investigate the non-allergic risk factors for EE. Read More

Presse Med 2019 Mar 26. Epub 2019 Mar 26.

CHU de Toulouse, hôpital Larrey, service de pneumologie, pôle des voies respiratoires, 31059 Toulouse, France.

Cough is divided into two categories: acute cough lasting less than 3 weeks, and chronic cough lasting more than 8 weeks. Acute cough is usually triggered by a viral infection of the upper airways. Evidence of treatment effectiveness is low and management of acute cough is complex in clinical practice. Read More

Nutrition 2019 Jan 25;62:201-208. Epub 2019 Jan 25.

Food Safety Research Center (salt), Semnan University of Medical Sciences, Semnan, Iran; Institute for Research and Innovation in Health (i3S), University of Porto, Porto, Portugal. Electronic address:

Tomato and its derived products have a very interesting nutritional value in addition to prominent antioxidant, anti-inflammatory, and anticancer activities. In terms of tomatoes are generally quite safe to eat. However, overall consumption varies from individual to individual. Read More

Ann Diagn Pathol 2019 Feb 10;40:40-44. Epub 2019 Feb 10.

Department of Gastroenterology, Peking University Third Hospital, 49 Rd. Garden, Haidian District, Beijing, PR China.

Aim: To assess the prevalence of the lesions in duodenal bulb mucosa and the relationship between duodenal lesions and upper gastrointestinal diseases, including helicobacter pylori infection.

Methods: Clinical, endoscopic and pathological data of the cases with duodenal bulb and gastric mucosal biopsy from January 2005 to May 2017 were analyzed retrospectively.

Results: A total of 3540 patients were enrolled. Read More

Ann Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

MINI: The reported prevalence of new-onset or worsening gastroesophageal reflux disease after sleeve gastrectomy is controversial. Subsequent esophagitis and Barrett's esophagus can be serious unintended sequalae. The aim of this study was to systematically appraise all existing published data to assess the effect of sleeve gastrectomy on gastroesophageal reflux, esophagitis, and Barrett's esophagus. Read More

JAMA Oncol 2019 Mar 28. Epub 2019 Mar 28.

Upper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

J Gastroenterol 2019 Mar 27. Epub 2019 Mar 27.

Center for Medical Statistics, 2-9-6 Higashi Shimbashi, Minato-ku, Tokyo, 105-0021, Japan.

Background: Long-term maintenance treatment of gastroesophageal reflux disease (GERD) is important to prevent relapse. Proton-pump inhibitors (PPIs) are used for both treatment and maintenance therapy of GERD. Recently, a potassium-competitive acid blocker vonoprazan was launched in Japan. Read More

SAGE Open Med Case Rep 2019 19;7:2050313X19838170. Epub 2019 Mar 19.

Department of Neonatology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.

Acquired bronchial stenosis is rare in children, usually caused by infection or traumatic granuloma due to chronic intubation. A case of severe acquired left bronchial stenosis successfully treated by conservative management for gastroesophageal reflux and atelectasis is reported. A male infant born at 24 weeks' gestation, weighing 461 g, presented with massive atelectasis of the left lower lobe and severe left bronchial stenosis, based on chest computed tomography performed for the evaluation of respiratory failure at the age of 8 months. Read More

Gastroenterol Res Pract 2019 17;2019:9672861. Epub 2019 Feb 17.

Department of Internal Medicine, Dongguk University College of Medicine, Ilsan Hospital, Goyang, Republic of Korea.

Background: Central obesity is suggested as a risk factor for gastroesophageal reflux diseases. The aim of this study was to evaluate the influences of a visceral fat area on the site of mucosal breaks in the esophagogastric junction (EGJ).

Methods: Subjects who underwent abdomen-computerized tomography and esophagogastroduodenoscopy for screening on the same day were evaluated between 2007 and 2016. Read More

Laryngoscope 2019 Mar 25. Epub 2019 Mar 25.

Hunan Key Laboratory of Medical Genetics, Central South University, Changsha, Hunan, People's Republic of China.

Objectives: Branchio-oto-renal (BOR) syndrome is characterized by branchial defects, hearing loss, preauricular pits, and renal anomalies, whereas patients with all symptoms except renal defects are diagnosed as branchio-oto (BO) syndrome. BOR/BO is one of the most common forms of autosomal dominant syndromic hearing loss, and EYA1 is the major causative gene. In this study, clinical and genetic analyses as well as auditory rehabilitation were performed in a Chinese family with BOR/BO syndrome. Read More

Pediatr Phys Ther 2019 04;31(2):148

Cindy Miles & Associates Whitehall, Pennsylvania.

Wiad Lek 2019 ;72(2):186-188

Department of Physiology of Humans and Animals of Ivan Franko National University of Lviv, Lviv, Ukraine.

Objective: Introduction: Gastroesophageal reflux disease (GERD) is one of the most common gastroduodenal diseases. The relationship between the hiatal hernia and the GERD is established. It is advisable to develop an accessible non-invasive diagnostic method for this combined pathology. Read More

Clin Rev Allergy Immunol 2019 Mar 22. Epub 2019 Mar 22.

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Abramson Research Building, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA.

Allergic eosinophilic esophagitis (EoE) is a chronic, allergen-mediated inflammatory disease of the esophagus, and the most common cause of prolonged dysphagia in children and young adults in the developed world. While initially undistinguished from gastroesophageal reflux disease-associated esophageal eosinophilia, EoE is now recognized as a clinically distinct entity that shares fundamental inflammatory features of other allergic conditions and is similarly increasing in incidence and prevalence. The clinical and epidemiologic associations between EoE and other allergic manifestations are well established. Read More