1,658 results match your criteria Gastroenterology Research and Practice [Journal]


Forehead against Resistance (FAR): Preliminary Findings from A Clinical Alternative to Shaker's Type of Exercise.

Gastroenterol Res Pract 2019 24;2019:9387578. Epub 2019 Mar 24.

Department of Radiodiagnosis, Kasturba Medical College, Mangalore, India.

Background: Reduced UES opening is a well-known risk factor for dysphagia. The Shaker exercise and the CTAR are the widely used intervention strategies to bring about effective UES opening. But there are well-known difficulties with the clinical use of these two exercise regimes. Read More

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http://dx.doi.org/10.1155/2019/9387578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451806PMC

A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases.

Gastroenterol Res Pract 2019 24;2019:4175960. Epub 2019 Mar 24.

Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Brazil.

Introduction: Abdominal and anorectal disorders may be the cause of clinical decompensation in neutropenic febrile patients, particularly those with hematologic diseases. Infection is a cause for concern for the colorectal surgeon. Some conditions have few manifestations and can lead to death within a short period of time. Read More

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http://dx.doi.org/10.1155/2019/4175960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451812PMC

Translational Research in Colorectal Cancer: Current Status and Future Perspectives of Multimodal Treatment Approach.

Gastroenterol Res Pract 2019 24;2019:2010259. Epub 2019 Mar 24.

Colorectal Unit, Hospital Universitario y Politécnico "La Fe", Valencia, Spain.

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http://dx.doi.org/10.1155/2019/2010259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451818PMC

Advances in Therapeutic Endoscopy.

Gastroenterol Res Pract 2019 12;2019:6253837. Epub 2019 Mar 12.

Division of Gastroenterology, Department of Medicine, Olive View-UCLA Medical Center, Sylmar, California, USA.

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http://dx.doi.org/10.1155/2019/6253837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434265PMC

Endoscopic Submucosal Single- or Multi-tunnel Dissection for Near-Circumferential and Circumferential Superficial Esophageal Neoplastic Lesions.

Gastroenterol Res Pract 2019 12;2019:2943232. Epub 2019 Mar 12.

Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 Guo Xue Alley, Chengdu, 610041 Sichuan, China.

This study reports the outcomes of endoscopic submucosal single-tunnel dissection or endoscopic submucosal multi-tunnel dissection for the treatment of esophageal neoplastic lesions of at least three-quarters of the esophageal circumference, including circumferential superficial esophageal neoplastic lesions. From July 2014 to February 2018, a total of 124 lesions underwent endoscopic submucosal tunnel dissection at our hospital. One to four submucosal tunnels were created in the oral to anal direction. Read More

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http://dx.doi.org/10.1155/2019/2943232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434308PMC

Serum Creatinine Level and APACHE-II Score within 24 h of Admission Are Effective for Predicting Persistent Organ Failure in Acute Pancreatitis.

Gastroenterol Res Pract 2019 10;2019:8201096. Epub 2019 Mar 10.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Aim: The present study was aimed at comparing serum markers and APACHE-II score to predict persistent organ failure (POF) in early acute pancreatitis (AP).

Methods: In this retrospective study, data from 6024 patients with AP were included within 24 h of their admission. Serum levels of urea nitrogen (BUN), creatinine, glucose, and hematocrit and APACHE-II score were analyzed for patients with AP. Read More

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http://dx.doi.org/10.1155/2019/8201096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431479PMC

A Practical Review of Cytomegalovirus in Gastroenterology and Hepatology.

Gastroenterol Res Pract 2019 7;2019:6156581. Epub 2019 Mar 7.

Division of Gastroenterology and Hepatology, Scripps Clinic, La Jolla, CA, USA.

Human cytomegalovirus (CMV) is a ubiquitous virus with a wide spectrum of pathology in humans. Host immunity is a major determinant of the clinical manifestation of CMV and can vary widely in the gastroenterology and hepatology practice setting. Immunocompetent patients generally develop a benign, self-limited mononucleosis-like syndrome whereas gastrointestinal tissue-invasive disease is more frequently seen in immunocompromised and inflammatory bowel disease patients. Read More

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https://www.hindawi.com/journals/grp/2019/6156581/
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http://dx.doi.org/10.1155/2019/6156581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431500PMC
March 2019
2 Reads

The New Jersey Bowel Preparation Scale: A More Objective and Detailed Scoring System for Screening Colonoscopies.

Gastroenterol Res Pract 2019 6;2019:8319747. Epub 2019 Mar 6.

Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.

Goals: The goal of this study was to develop an objective and detailed scoring system to assess the quality of bowel preparation.

Background: The quality of bowel preparation impacts the success of the colonoscopy. We developed and compared a new bowel preparation scoring system, the New Jersey Bowel Preparation Scale (NJBPS), with existing systems that are limited by a lack of detail and objectivity in the Boston Bowel Preparation Scale (BBPS) and the Ottawa Bowel Preparation Scale (OBPS). Read More

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http://dx.doi.org/10.1155/2019/8319747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431366PMC

RACK1 Acts as a Potential Tumor Promoter in Colorectal Cancer.

Gastroenterol Res Pract 2019 10;2019:5625026. Epub 2019 Mar 10.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006 Jiangxi Province, China.

Background: The receptor of activated protein kinase C 1 (RACK1) promotes the progression and invasion of several cancers. However, the role of RACK1 in the pathogenesis of colorectal cancer (CRC) has not been clearly defined. Herein, we aimed to investigate the biological role of RACK1 in CRC. Read More

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http://dx.doi.org/10.1155/2019/5625026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431438PMC
March 2019
1 Read

Contrast-Enhanced EUS for Differential Diagnosis of Pancreatic Masses: A Meta-Analysis.

Gastroenterol Res Pract 2019 6;2019:1670183. Epub 2019 Mar 6.

Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.

Background: Though methods for the diagnosis of pancreatic masses are various, such as ultrasonography (US), computed tomography (CT), endoscopic ultrasonography (EUS), and contrast-enhanced computed tomography (CE-CT), their sensitivity, specificity, and accuracy are not quite satisfying. Contrast-enhanced endoscopic ultrasonography (CE-EUS), as a new technique, has its own unique advantages in diagnosing pancreatic disease. However, its sensitivity, specificity, and accuracy are still controversial. Read More

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http://dx.doi.org/10.1155/2019/1670183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431391PMC

Laparoscopic versus Open Surgery in Lateral Lymph Node Dissection for Advanced Rectal Cancer: A Meta-Analysis.

Gastroenterol Res Pract 2019 5;2019:7689082. Epub 2019 Mar 5.

Department of General Surgery, Guangdong General Hospital (Guangdong Academy of Medical Sciences), Guangzhou, Guangdong Province 510080, China.

Aim: To compare the clinical efficacies between laparoscopic and conventional open surgery in lateral lymph node dissection (LLND) for advanced rectal cancer.

Methods: We comprehensively searched PubMed, Embase, Cochrane Library, CNKI, and Wanfang Data and performed a cumulative meta-analysis. According to inclusion criteria and exclusion criteria, all eligible randomized controlled trials (RCTs) or retrospective or prospective comparative studies assessing the two techniques were included, and then a meta-analysis was performed by using RevMan 5. Read More

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https://www.hindawi.com/journals/grp/2019/7689082/
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http://dx.doi.org/10.1155/2019/7689082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425322PMC
March 2019
4 Reads

Same-Day Regimen as an Alternative to Split Preparation for Colonoscopy: A Systematic Review with Meta-Analysis.

Gastroenterol Res Pract 2019 28;2019:7476023. Epub 2019 Feb 28.

Gastroenterology and Endoscopy Unit, L. Curto Hospital, Polla, Italy.

Background: Split bowel preparation is the best regimen for colonoscopy. However, the same-day regimen can represent a valid alternative, but its use is limited by concerns about its cleansing ability, and to date, no convincing data support its use for routine colonoscopies.

Aim: To evaluate the cleansing, compliance, and adverse event rates of the same-day compared to the split regimen. Read More

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http://dx.doi.org/10.1155/2019/7476023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421828PMC
February 2019
1.502 Impact Factor

Factors Affecting Proximal Colon Cleansing Based on Bowel Movement Kinetics: A Prospective Observational Study.

Gastroenterol Res Pract 2019 3;2019:7032971. Epub 2019 Mar 3.

Department of Internal Medicine, St Paul's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Background: Previous studies have suggested that relatively poor bowel preparation in the proximal colon, compared to that in the distal colon, could decrease the usefulness of colonoscopy. The aim of this study was to determine whether the "first defecation time" after polyethylene glycol (PEG) administration affects the cleansing quality in the proximal colon.

Methods: A total of 425 individuals who were scheduled to undergo a screening colonoscopy were enrolled prospectively at the healthcare center of St. Read More

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http://dx.doi.org/10.1155/2019/7032971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421731PMC
March 2019
1 Read

Esophageal Impedance-pH Monitoring and Pharyngeal pH Monitoring in the Diagnosis of Extraesophageal Reflux in Children.

Gastroenterol Res Pract 2019 3;2019:6271910. Epub 2019 Mar 3.

Department of Pediatric Allergy, Gastroenterology and Nutrition, Medical University of Lodz, Lodz, Poland.

Various clinical symptoms are attributed to extraesophageal reflux disease (EERD). Multichannel intraluminal impedance-pH monitoring (MII-pH) is considered to correlate symptoms with acid and nonacid gastroesophageal reflux (GER) events. Pharyngeal pH monitoring (Dx-pH) is considered to correlate the decrease in the pH level in the oropharynx with reported symptoms and to diagnose supraesophageal reflux. Read More

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http://dx.doi.org/10.1155/2019/6271910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421743PMC
March 2019
5 Reads

Lewis Score on Capsule Endoscopy as a Predictor of the Risk for Crohn's Disease-Related Emergency Hospitalization and Clinical Relapse in Patients with Small Bowel Crohn's Disease.

Gastroenterol Res Pract 2019 3;2019:4274257. Epub 2019 Mar 3.

Department of Endoscopy, Nagoya University Hospital, Nagoya, Japan.

Background: Small bowel capsule endoscopy (CE) is a useful tool for evaluating the mucosal changes in patients with Crohn's disease (CD). The Lewis score (LS) on CE could be used to objectively assess the inflammatory activity of the small bowel mucosa. However, only few reports on the correlation between the LS and CD prognosis exist. Read More

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http://dx.doi.org/10.1155/2019/4274257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421745PMC

The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis.

Gastroenterol Res Pract 2019 28;2019:3480732. Epub 2019 Feb 28.

Centre for Lipid Research & Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, 400016 Chongqing, China.

Objectives: Our aim of this study is to compare the efficacy of flupentixol-melitracen in the adjuvant therapy of ulcerative colitis patients in the Chinese population.

Methods: Both the RevMan 5.2 and the Stata 12. Read More

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http://dx.doi.org/10.1155/2019/3480732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421776PMC
February 2019
1 Read

A Prospective Randomized Trial to Assess the Antireflux Effect of Antireflux Mucosectomy in the Porcine Model.

Gastroenterol Res Pract 2019 24;2019:3286738. Epub 2019 Feb 24.

Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.

Background: Both long-term proton pump inhibitor use and surgical fundoplication have potential drawbacks as treatments for chronic gastroesophageal reflux disease (GERD). Our aim was to investigate the potential efficacy of antireflux mucosectomy (ARMS) in porcine and determine the optimal circumference of resection in relation to gastroesophageal junction (GEJ).

Methods: Nine pigs were allocated into the following 3 groups by computerized randomization: group A: control, group B: 1/3 circumference of the esophagus, and group C: 2/3 circumference of the esophagus. Read More

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http://dx.doi.org/10.1155/2019/3286738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421794PMC
February 2019

Clinical Outcomes and Adverse Events of Endoscopic Submucosal Dissection for Gastric Tube Cancer after Esophagectomy.

Gastroenterol Res Pract 2019 3;2019:2836860. Epub 2019 Mar 3.

Department of Gastroenterology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, Japan.

Background And Aim: The clinical outcomes of endoscopic submucosal dissection (ESD) for gastric tube cancer (GTC) after esophagectomy remain unclear. The aim of this study was to evaluate the clinical outcomes and safety of ESD for GTC.

Patients And Methods: Twenty GTC lesions in 18 consecutive patients who underwent ESD between February 2008 and June 2018 were included in this retrospective study. Read More

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http://dx.doi.org/10.1155/2019/2836860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421774PMC
March 2019
1 Read

Increased Mortality from Extrapancreatic Infections in Hospitalized Patients with Acute Pancreatitis.

Gastroenterol Res Pract 2019 28;2019:2789764. Epub 2019 Feb 28.

National Institute of Medical Science and Nutrition Salvador Zubiran, Department of Gastroenterology, Mexico City, Mexico.

Nosocomial extrapancreatic infections in patients with acute pancreatitis (AP) are associated with a higher mortality even after adjusting the risk for the severity of the pancreatitis. The aim of this study was to describe the clinical features of hospitalized patients with AP who died during their hospitalization and to evaluate risk factors associated with mortality. We performed a descriptive study of the clinical features of adult patients who died from AP during their hospitalization and a case control study with a paired group of patients that survived AP during a 10-year period. Read More

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https://www.hindawi.com/journals/grp/2019/2789764/
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http://dx.doi.org/10.1155/2019/2789764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421823PMC
February 2019
5 Reads

The Celiac Disease Patients' Ability to Experience Pleasure.

Gastroenterol Res Pract 2019 28;2019:2030751. Epub 2019 Feb 28.

Celiac Center, AOU San Giovanni di Dio e Ruggi di Aragona, University of Salerno, Department of Medicine, Surgery, and Dentistry Scuola Medica Salernitana, Salerno, Italy.

The motivation or ability to experience pleasure has been scarcely studied in celiac disease (CeD). We aimed to investigate the hedonistic feelings/anhedonia and sexual pleasure in CeD patients on a gluten-free diet (GFD) compared to controls. We recruited adult CeD patients at follow-up consecutively visited from April 2017 to April 2018 and controls from the hospital staff and friends of CeD patients. Read More

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http://dx.doi.org/10.1155/2019/2030751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421785PMC
February 2019
1 Read

The Impact of Surgery on Long-Term Survival of Patients with Primary Gastric Diffuse Large B-Cell Lymphoma: A SEER Population-Based Study.

Gastroenterol Res Pract 2019 24;2019:9683298. Epub 2019 Feb 24.

Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.

Background: The aim of this retrospective study was to compare the long-term survival of patients receiving conservative with surgical treatment to analyze the prognostic factors and the impact of surgery on oncological outcomes of patients with primary gastric diffuse large B-cell lymphoma.

Methods: A total of 2647 patients diagnosed with primary gastric diffuse large B-cell lymphoma from 1998 to 2014 were extracted from SEER database. Propensity matching was performed to compare the clinicopathological characteristics of the two groups. Read More

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http://dx.doi.org/10.1155/2019/9683298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409055PMC
February 2019
2 Reads

Response to: Comment on "Factors Associated with Recurrent Ulcers in Patients with Gastric Surgery after More Than 15 Years: A Cross-Sectional Single-Center Study".

Gastroenterol Res Pract 2019 24;2019:9214597. Epub 2019 Feb 24.

Pathological Department, Emergency County Hospital, Gheorghe Marinescu 50, Tirgu Mures, 540136 Mures, Romania.

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http://dx.doi.org/10.1155/2019/9214597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409013PMC
February 2019
1 Read

Narrow-Band Imaging Colonoscopy to Assess Mucosal Angiogenesis in Ulcerative Colitis.

Gastroenterol Res Pract 2019 24;2019:8312624. Epub 2019 Feb 24.

Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.

Background And Aim: It has been documented that angiogenesis is a largely unstudied component of the pathogenesis of ulcerative colitis (UC). Under narrow-band imaging (NBI) colonoscopy, the mucosal vascular pattern (MVP) can be visualized without the use of dyes. The aim of this study was to assess the grade of mucosal angiogenesis based on the MVP in UC. Read More

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http://dx.doi.org/10.1155/2019/8312624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409060PMC
February 2019
1 Read

Association of Ulcerative Colitis with Gene Polymorphisms and Its Colonic Expression in Chinese Patients.

Gastroenterol Res Pract 2019 24;2019:4052168. Epub 2019 Feb 24.

Department of Gastroenterology, The Second Affiliated Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou, 325000 Zhejiang Province, China.

Abnormalities of forkhead box P3 (FOXP3) are implicated in various autoimmune diseases. This study is aimed at investigating the association of ulcerative colitis (UC) with polymorphisms and its colonic expression in Chinese patients. Polymorphisms of rs3761548, rs2232365, rs2294021, and rs3761547 were examined in 472 UC patients and 525 healthy controls using the SNaPshot method. Read More

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http://dx.doi.org/10.1155/2019/4052168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409000PMC
February 2019
2 Reads

The Influences of Visceral Fat Area on the Sites of Esophageal Mucosal Breaks in Subjects with Gastroesophageal Reflux Diseases.

Gastroenterol Res Pract 2019 17;2019:9672861. Epub 2019 Feb 17.

Department of Internal Medicine, Dongguk University College of Medicine, Ilsan Hospital, Goyang, Republic of Korea.

Background: Central obesity is suggested as a risk factor for gastroesophageal reflux diseases. The aim of this study was to evaluate the influences of a visceral fat area on the site of mucosal breaks in the esophagogastric junction (EGJ).

Methods: Subjects who underwent abdomen-computerized tomography and esophagogastroduodenoscopy for screening on the same day were evaluated between 2007 and 2016. Read More

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http://dx.doi.org/10.1155/2019/9672861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398014PMC
February 2019
2 Reads

Validation of a Digital Support App to Assess Inflammatory Disease Activity and Mental Health Patient-Reported Outcomes (PROs): A Pilot Investigation.

Gastroenterol Res Pract 2019 17;2019:7618468. Epub 2019 Feb 17.

Faculty of Health, Arts & Design, Swinburne University of Technology, Hawthorn 3122, Australia.

Background: Real-time collection of mental health and disease activity patient-reported outcomes (PROs) are essential to assist clinicians in delivering optimal holistic health care. The aim of this pilot study was to validate a digital support tool (DST) delivered via a tablet device in an outpatient setting to assess IBD activity and psychological distress.

Methods: 48 individuals (26 females; average age: 40. Read More

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http://dx.doi.org/10.1155/2019/7618468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398025PMC
February 2019
1 Read

Calponin 3 Regulates Cell Invasion and Doxorubicin Resistance in Gastric Cancer.

Gastroenterol Res Pract 2019 18;2019:3024970. Epub 2019 Feb 18.

Division of Applied Life Science (BK21 Plus), Research Institute of Life Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.

Calponin 3 (CNN3) is an F-actin-binding protein that regulates actin cytoskeletal rearrangement. However, the role of CNN3 in cancer cell invasion and resistance to chemotherapeutic agents has not yet been investigated. The present study was undertaken to investigate whether CNN3 influences cancer-related phenotypes in gastric cancer. Read More

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http://dx.doi.org/10.1155/2019/3024970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398029PMC
February 2019

Serum Resolvin E1 Levels and Its Relationship with Disease Activity in Ulcerative Colitis.

Gastroenterol Res Pract 2019 14;2019:6258327. Epub 2019 Feb 14.

Department of Gastroenterology, Katip Çelebi University, Atatürk Education and Research Hospital, İzmir, Turkey.

Background: Resolvins originate from -3 PUFA (polyunsaturated fatty acid) precursors and play a role in the resolution of inflammation. The aim of this study was to determine the serum Resolvin E1 levels in patients with ulcerative colitis (UC) and to evaluate the relationship between the serum Resolvin E1 levels and ulcerative colitis disease activity.

Methods: In this observational study, serum samples were collected from 51 patients with UC and 30 healthy controls for the determination of Resolvin E1 levels. Read More

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http://dx.doi.org/10.1155/2019/6258327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393930PMC
February 2019
1 Read

B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis.

Gastroenterol Res Pract 2019 6;2019:7568410. Epub 2019 Feb 6.

Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Purpose: Pancreatitis can lead to systemic inflammatory response, but the relationship between lymphocyte changes and patients with pancreatitis remains unclear. In this study, we evaluated the feedback function of changes in peripheral lymphocyte subsets on the condition of patients with pancreatitis.

Materials And Methods: 131 acute pancreatitis (AP) patients and 11 chronic pancreatitis (CP) patients constituted the patients' group; 20 healthy individuals were enrolled as healthy controls (HC). Read More

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http://dx.doi.org/10.1155/2019/7568410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381581PMC
February 2019
1 Read

Impact of Helicobacter pylori Infection on Gastric Variceal Bleeding among Patients with Liver Cirrhosis.

Gastroenterol Res Pract 2019 10;2019:6529420. Epub 2019 Feb 10.

Tropical Medicine Department, Tanta University, Egypt.

Background And Aims: Currently, it is well known that Helicobacter pylori- (-) related peptic ulcer is one of the main causes of nonvariceal bleeding in cirrhotic patients. However, there is a lack of data to identify the exact effect of infection on variceal bleeding. This study was conducted to identify the impact of infection on gastric variceal bleeding in cirrhotic patients. Read More

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http://dx.doi.org/10.1155/2019/6529420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387698PMC
February 2019
1 Read
1.502 Impact Factor

MHC Class 1 and PDL-1 Status of Primary Tumor and Lymph Node Metastatic Tumor Tissue in Gastric Cancers.

Gastroenterol Res Pract 2019 6;2019:4785098. Epub 2019 Feb 6.

Adnan Menderes University, Medical School, Department of Pathology, Aydin, Turkey.

The prognosis of metastatic gastric cancer is poor. Despite the use of VEGF-, EGFR-, and HER2-targeting agents, prognosis is still poor in advanced gastric cancer. Although cancer immunotherapy responds well in some patients, clinical use is limited due to unanswered patients. Read More

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http://dx.doi.org/10.1155/2019/4785098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381579PMC
February 2019

Electroacupuncture and Moxibustion Improved Anxiety Behavior in DSS-Induced Colitis Mice.

Gastroenterol Res Pract 2019 7;2019:2345890. Epub 2019 Feb 7.

Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.

Background And Aims: Psychological disorders are prevalent in patients with inflammatory bowel disease, but the underlying mechanisms remain unknown. The aim of this study was to study whether electroacupuncture (EA) and moxibustion (MB) can improve anxiety behavior in DSS-induced colitis mice and to investigate whether this effect is related to hypothalamic-pituitary-adrenocortical (HPA) axis.

Methods: The colitis model was established by drinking 2. Read More

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http://dx.doi.org/10.1155/2019/2345890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383400PMC
February 2019

Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme.

Gastroenterol Res Pract 2019 6;2019:1592306. Epub 2019 Feb 6.

Department of Histopathology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

Background: As the malignant potential of sessile serrated lesions/polyps (SSL/Ps) and traditional serrated adenomas (TSAs) has been clearly demonstrated, it is important that serrated polyps are identified and correctly classified histologically.

Aim: Our aim was to characterize the clinicopathological features of a series of SSL/Ps & TSAs, to assess the accuracy of the pathological diagnosis, the incidence, and the rate of dysplasia in SSL/Ps & TSAs.

Methods: We identified all colorectal serrated polyps between 01/01/2004 and 31/05/2016, by searching the laboratory information system for all cases assigned a "serrated adenoma" SNOMED code. Read More

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http://dx.doi.org/10.1155/2019/1592306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381559PMC
February 2019

Pneumo-PET-CT: Initial Results of This Novel Technique on the Evaluation of Esophageal and Gastric Tumors with Anatomic-Surgical Correlation.

Gastroenterol Res Pract 2019 5;2019:4123851. Epub 2019 Feb 5.

Diagnóstico por Imágenes, Hospital Italiano de Buenos Aires, Juan Domingo Peron 4190 (C1199AAB), Ciudad Autónoma de Buenos Aires, Argentina.

We present the initial results of a novel hybrid scanning-based technique that combines pneumo-computed tomography (PNCT) with positron emission tomography (PET) using 2-(fluorine-18) fluoro-2-deoxy-D-glucose (FDG). We denominate it pneumo-PET-CT. The focus of our discussion will be on the description of the pneumo-PET-CT technique and the interpretation criteria with emphasis on its benefits and applications in the presurgical and postneoadjuvant therapy evaluation of esophageal, esophagogastric junction (EGJ), and gastric tumors. Read More

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http://dx.doi.org/10.1155/2019/4123851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379876PMC
February 2019

The Application of Extraperitoneal Ostomy Combined with Pelvic Peritoneal Reconstruction in Laparoscopic Abdominoperineal Resection for Rectal Cancer.

Gastroenterol Res Pract 2019 5;2019:3015958. Epub 2019 Feb 5.

Department of General Surgery, General Surgery Institute of Yangzhou, Northern Jiangsu Province Hospital, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu 225000, China.

Background: Due to the technical difficulty, it is not common to close the pelvic peritoneum in laparoscopic abdominoperineal resection (LAPR) in China, which increases the risk of related complications. Permanent sigmoid colostomy is performed through the transperitoneal route conventionally in LAPR. This leads to the high occurrence of parastomal hernias and bowel obstructions. Read More

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http://dx.doi.org/10.1155/2019/3015958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379842PMC
February 2019
1 Read

Comparing PET/MRI with PET/CT for Pretreatment Staging of Gastric Cancer.

Gastroenterol Res Pract 2019 3;2019:9564627. Epub 2019 Feb 3.

Department of General Surgery & Institute of General Surgery, Chinese People's Liberation Army General Hospital, Fuxing Road 28, Beijing 100853, China.

18F-FDG PET/MRI has been applied to the diagnosis and preoperative staging in various tumor types; however, reports using PET/MRI in gastric cancer are rare because of motion artifacts. We investigated the value of PET/MRI for preoperative staging compared with PET/CT in gastric cancer (GC). Thirty patients with confirmed GC underwent PET/CT and PET/MRI. Read More

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https://www.hindawi.com/journals/grp/2019/9564627/
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http://dx.doi.org/10.1155/2019/9564627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378050PMC
February 2019
4 Reads

Advances in Translational Research and Clinical Care in Pancreatic Cancer: Where Are We Headed?

Gastroenterol Res Pract 2019 4;2019:7690528. Epub 2019 Feb 4.

Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, USA.

While significant advances have been made in the treatment of many different solid tumors, pancreatic cancer remains a glaring exception. Overall 5-year survival rates for pancreatic cancer remain in the single digits. While newer chemotherapy regimens such as FOLFIRINOX and nab-paclitaxel/gemcitabine have demonstrated modest improvement in survival benefit for metastatic disease and have improved the resectability rates of previously borderline or locally advanced tumors, clinically significant improvements from immunotherapy and targeted therapy remain to be demonstrated. Read More

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http://dx.doi.org/10.1155/2019/7690528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378762PMC
February 2019

Do Self-Expanding Metal Stents as a Bridge to Surgery Benefit All Patients with Obstructive Left-Side Colorectal Cancers?

Gastroenterol Res Pract 2019 3;2019:7418348. Epub 2019 Feb 3.

Department of General Surgery (Emergency Surgery), Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001 Fujian, China.

Background: Self-expanding metal stents (SEMS) have been increasingly used in patients with obstructive left-sided colorectal cancer (OLCC); however, stent-specific complications (e.g., perforations) might worsen the long-term survival outcome. Read More

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https://www.hindawi.com/journals/grp/2019/7418348/
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http://dx.doi.org/10.1155/2019/7418348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377959PMC
February 2019
4 Reads

Significance of EGFR and PTEN Expression and PLR and NLR for Predicting the Prognosis of Epithelioid Malignant Peritoneal Mesothelioma.

Gastroenterol Res Pract 2019 4;2019:7103915. Epub 2019 Feb 4.

Cangzhou Medical College, Cangzhou, Hebei 061001, China.

Objective: The aim of our study was to investigate the expression of EGFR and PTEN in tissues and measure the serum platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) to evaluate the prognostic factors of patients with epithelioid malignant peritoneal mesothelioma (MPeM).

Methods: 33 patients of pathologically diagnosed epithelioid MPeM tissues were analyzed using immunohistochemistry to detect EGFR and PTEN; the PLR and NLR were determined by using a routine blood test. We analyzed the relationships of these markers to age, sex, asbestos exposure, elevated platelet count, ascites, and clinical stage. Read More

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https://www.hindawi.com/journals/grp/2019/7103915/
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http://dx.doi.org/10.1155/2019/7103915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378794PMC
February 2019
7 Reads

Noninvasive Evaluation of Liver Function in Morbidly Obese Patients.

Gastroenterol Res Pract 2019 3;2019:4307462. Epub 2019 Feb 3.

Department of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074 Aachen, Germany.

Background: More than half of the obese patients develop nonalcoholic fatty liver disease (NAFLD), which may further progress to nonalcoholic steatohepatitis (NASH) and cirrhosis. The aim of this study was to assess alterations in liver function in obese patients with a noninvasive liver function test.

Methods: In a prospective cohort study 102 morbidly obese patients undergoing bariatric surgery were evaluated for their liver function. Read More

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https://www.hindawi.com/journals/grp/2019/4307462/
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http://dx.doi.org/10.1155/2019/4307462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378040PMC
February 2019
6 Reads

Prior Esophagogastric Devascularization Followed by Splenectomy for Liver Cirrhosis with Portal Hypertension: A Modified Laparoscopic Technique.

Gastroenterol Res Pract 2019 3;2019:2623749. Epub 2019 Feb 3.

Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Purpose: This study was conducted to introduce a novel modified surgical technique for laparoscopic splenectomy and esophagogastric devascularization (LSED) and its safety and efficiency.

Methods: From June 2016 to November 2017, 86 patients were diagnosed with portal hypertension and serious gastroesophageal varices in our center. Of them, 32 patients underwent LSED and 54 received the modified LSED. Read More

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http://dx.doi.org/10.1155/2019/2623749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377971PMC
February 2019
1 Read
1.502 Impact Factor

Magnetic-Resonance-Imaging Texture Analysis Predicts Early Progression in Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiation.

Gastroenterol Res Pract 2019 17;2019:8505798. Epub 2019 Jan 17.

Istituto Toscano Tumori, Florence, Italy.

Background: We hypothesized that texture analysis (TA) from the preoperative MRI can predict early disease progression (ePD), defined as the percentage of patients who relapsed or showed distant metastasis within three months from the radical surgery, in patients with locally advanced rectal cancer (LARC, stage II and III, AJCC) undergoing neoadjuvant chemoradiotherapy (C-RT).

Methods: This retrospective monoinstitutional cohort study included 49 consecutive patients in total with a newly diagnosed rectal cancer. All the patients underwent baseline abdominal MRI and CT scan of the chest and abdomen to exclude distant metastasis before C-RT. Read More

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http://dx.doi.org/10.1155/2019/8505798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360039PMC
January 2019
3 Reads

Quantitative Analysis of HER2 Amplification by Droplet Digital PCR in the Follow-Up of Gastric Cancer Patients Being Treated with Trastuzumab after Surgery.

Gastroenterol Res Pract 2019 31;2019:1750329. Epub 2019 Jan 31.

Department of Gastrointestinal Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, China.

Background: Circulating tumor DNA (ctDNA) derived from tumors is a promising biomarker for monitoring tumor status and evaluating therapeutic effects and prognosis. We studied the plasma human epidermal growth factor receptor 2 (HER2) amplification in gastric cancer (GC) patients by droplet digital PCR (ddPCR) during therapy with trastuzumab.

Methods: A total of 12 patients were recruited after surgery. Read More

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http://dx.doi.org/10.1155/2019/1750329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374807PMC
January 2019
1 Read
1.502 Impact Factor

Effect of a Novel Patient Garment on Perceived Privacy during Colonoscopy: A Simple Approach to Minimize Embarrassment.

Gastroenterol Res Pract 2019 27;2019:2467101. Epub 2019 Jan 27.

Division of Gastroenterology, Yale New Haven Hospital, 40 Temple Street, New Haven, CT, USA.

Background: In the United States, patients wear a one-piece, reusable cloth gown during colonoscopy procedures. Many patients report embarrassment related to bodily exposure during colonoscopy. This may limit participation in colorectal cancer screening programs. Read More

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http://dx.doi.org/10.1155/2019/2467101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369509PMC
January 2019

Preoperative Serum Platelet-Lymphocyte Ratio as a Prognostic Factor in Cholangiocarcinoma Patients after Radical Resection: A Retrospective Analysis of 119 Patients.

Gastroenterol Res Pract 2019 28;2019:8506967. Epub 2019 Jan 28.

Department of Oncology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, Jiangxi 330006, China.

Aims: Although prognostic markers are important to establish therapeutic strategies in patients for conducting radical resection of cholangiocarcinoma (CCA), there is still a lack of simple, valid, and repeatable markers in clinical settings. We aim to evaluate the prognostic value of the preoperative serum platelet-lymphocyte ratio (PLR) in CCA patients who underwent radical resection.

Methods: We retrospectively analyzed CCA patients who underwent radical resection surgery in our institution from January 2011 to June 2016. Read More

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http://dx.doi.org/10.1155/2019/8506967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369483PMC
January 2019
1 Read

Diagnosis and Treatment of Atraumatic Splenic Rupture: Experience of 8 Cases.

Gastroenterol Res Pract 2019 28;2019:5827694. Epub 2019 Jan 28.

Department of General Surgery, Xuanwu Hospital, Capital Medical University, Number 45, Changchun Street, Beijing 100053, China.

Atraumatic splenic rupture (ASR) is rare but life threatening. In this study, we retrospectively described our experience on the diagnosis and treatment of 8 patients (male: 6; female: 2; mean age: 49.6) with ASR. Read More

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http://dx.doi.org/10.1155/2019/5827694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369493PMC
January 2019
1 Read
1.502 Impact Factor

The Value of Pepsinogen in GC Screening: A Systematic Review and Meta-Analysis.

Gastroenterol Res Pract 2019 21;2019:7087232. Epub 2019 Jan 21.

School of Humanities and Management Science, Wannan Medical College, Wenchang West Road, 22 Wuhu, China.

Background: The current gold standard for gastric cancer (GC) screening is pathology or a barium meal followed by X-ray. This is not applicable to a wide range of screening capabilities due to the lack of operability. This article used a meta-analysis to evaluate the value of pepsinogen (PG) screening for GC. Read More

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http://dx.doi.org/10.1155/2019/7087232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360615PMC
January 2019

Clinicopathological Factors Influencing Lymph Node Yield in Colorectal Cancer: A Retrospective Study.

Gastroenterol Res Pract 2019 22;2019:5197914. Epub 2019 Jan 22.

Department of General and Emergency Surgery, San Raffaele Scientific Institute, 20132 Milan, Italy.

Many colorectal resections do not meet the minimum of 12 lymph nodes (LNs) recommended by the American Joint Committee on Cancer for accurate staging of colorectal cancer. The aim of this study was to investigate factors affecting the number of the adequate nodal yield in colorectal specimens subject to routine pathological assessment. We have retrospectively analysed the data of 2319 curatively resected colorectal cancer patients in San Raffaele Scientific Institute, Milan, between 1993 and 2017 (1259 colon cancer patients and 675 rectal cancer patients plus 385 rectal cancer patients who underwent neoadjuvant therapy). Read More

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http://dx.doi.org/10.1155/2019/5197914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362492PMC
January 2019

A Proposal of a Personalized Surveillance Strategy for Gastric Cancer: A Retrospective Analysis of 9191 Patients.

Gastroenterol Res Pract 2019 22;2019:3248727. Epub 2019 Jan 22.

Department of Surgical Oncology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China.

Background: In gastric cancer, various surveillance strategies are suggested in international guidelines. The current study is intended to evaluate the current strategies and provide more personalized proposals for personalized cancer medicine.

Materials And Methods: In the aggregate, 9191 patients with gastric cancer after gastrectomy from 1998 to 2009 were selected from the Surveillance, Epidemiology, and End Results database. Read More

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http://dx.doi.org/10.1155/2019/3248727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362503PMC
January 2019
3 Reads

Endoscopic Sphincterotomy before Fully Covered Metal Stent Placement Is Not Required for Distal Malignant Biliary Stricture due to a Pancreatic Head Tumor.

Gastroenterol Res Pract 2019 15;2019:9675347. Epub 2019 Jan 15.

Department of Gastroenterology and Hepatology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511, Japan.

Background/aims: Endoscopic sphincterotomy (EST) is often performed before fully covered self-expandable metal stent (FCSEMS) placement in order to prevent pancreatitis. However, it is not clear whether EST prevents pancreatitis or affects other adverse events (AEs). This study is conducted to evaluate the necessity of EST before FCSEMS placement for distal malignant biliary strictures due to a pancreatic head tumor. Read More

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https://www.hindawi.com/journals/grp/2019/9675347/
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http://dx.doi.org/10.1155/2019/9675347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350600PMC
January 2019
13 Reads