23,511 results match your criteria Gastroenteritis Bacterial


Infection Triggering Acute Relapse in Pediatric Crohn's Disease.

Case Rep Infect Dis 2019 20;2019:2094372. Epub 2019 Mar 20.

Department of Pediatrics, Western University, London, Ontario, Canada N6A 3K7.

Crohn's disease exacerbations can often be associated with bacterial infections causing gastroenteritis. We report a child who experienced exacerbation of his Crohn's disease associated with a positive stool culture for . Endoscopy showed features of moderate inflammation similar to exacerbation of Crohn's disease. Read More

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http://dx.doi.org/10.1155/2019/2094372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446101PMC

Invasive Salmonella infections among children in Bintulu, Sarawak, Malaysian Borneo: a 6-year retrospective review.

BMC Infect Dis 2019 Apr 18;19(1):330. Epub 2019 Apr 18.

Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.

Background: Invasive Salmonella infections result in significant morbidity and mortality in developing countries. In Asia, typhoid and paratyphoid fever are reported to be the major invasive Salmonella infections, while invasive non-typhoidal Salmonella (iNTS) infections are believed to be uncommon. Data from Sarawak, in Malaysian Borneo, are limited. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3963-xDOI Listing
April 2019
1 Read
2.613 Impact Factor

CPHLN recommendations for the laboratory detection of Shiga toxin-producing (O157 and non-O157).

Can Commun Dis Rep 2018 Nov 1;44(11):304-307. Epub 2018 Nov 1.

National Microbiology Laboratory, MB & ON.

Shiga toxin-producing (STEC) are important enteric pathogens responsible for sporadic cases and outbreaks of gastroenteritis. O157:H7/NM (STEC O157) are the most commonly known STEC serotypes but it is now increasingly apparent that non-O157 STEC serotypes have been underreported in the past because they were not part of routine screening in many front-line laboratories. The Canadian Public Health Laboratory Network (CPHLN) has identified the need for improved detection and surveillance of non-O157 STEC and has developed the following recommendations to assist in the decision-making process for clinical and reference microbiology laboratories. Read More

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https://www.canada.ca/content/dam/phac-aspc/documents/servic
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http://dx.doi.org/10.14745/ccdr.v44i11a06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449107PMC
November 2018
2 Reads

Carvacrol antimicrobial wash treatments reduce Campylobacter jejuni and aerobic bacteria on broiler chicken skin.

Poult Sci 2019 Apr 16. Epub 2019 Apr 16.

Poultry Production and Product Safety Research Unit, USDA-ARS, AR 72701, USA.

Campylobacter jejuni, a major cause of human gastroenteritis worldwide, is often associated with the consumption of contaminated poultry products. With increasing consumer preference to natural and minimally processed foods, interventions utilizing natural antimicrobials for controlling C. jejuni on poultry products are gaining popularity. Read More

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http://dx.doi.org/10.3382/ps/pez198DOI Listing
April 2019
1 Read

Comparative Evaluation of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis.

J Clin Microbiol 2019 Apr 10. Epub 2019 Apr 10.

Sections of Pediatric Emergency Medicine and Gastroenterology, Alberta Children's Hospital, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

: Although enteric multianalyte syndromic panels are increasingly employed, direct comparisons with traditional methods and the inclusion of host phenotype correlations are limited.: 3089 children with gastroenteritis submitted stool, rectal-swab specimens, and clinical data. Primary outcome was bacterial pathogen detection agreement for shared targets between culture and the Luminex xTAG® Gastrointestinal Pathogen Panel (GPP). Read More

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http://dx.doi.org/10.1128/JCM.00205-19DOI Listing
April 2019
2 Reads

Heat stress, Eimeria spp. and C. perfringens infections alone or in combination modify gut Th1/Th2 cytokine balance and avian necrotic enteritis pathogenesis.

Vet Immunol Immunopathol 2019 Apr 4;210:28-37. Epub 2019 Mar 4.

Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, SP, Brazil.

Information on the dynamics of the chicken immune system during bacterial or parasite challenge in the presence or absence of stressful situations may provide a better understanding of the complex mechanisms behind these diseases. Necrotic enteritis (NE) had been controlled previously by the proper use of antimicrobial agents; however, more recently, NE has reemerged in many countries. The imposed restrictions on antimicrobial use and/or the intensive productive programs implemented by producers are challenges the birds, leading to large host adaptive responses that in many instances are like those elicited by stressors. Read More

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http://dx.doi.org/10.1016/j.vetimm.2019.03.001DOI Listing
April 2019
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[Retrospective study on the eradication of Swine Dysentery (Brachyspira hyodysenteriae) in Switzerland].

Schweiz Arch Tierheilkd 2019 Apr;161(4):217-230

Schweineklinik, Vetsuisse-Fakultät, Universität Bern.

Introduction: The eradication of Swine Dysentery (infection with Brachyspira hyodysenteriae) within farm populations is extremely complex and its success is significantly linked to the compliance of pig farmers performing the onsite eradications, emphasizing the importance of their motivation. The present study focuses on the motivation and satisfaction of Swiss pig farmers concerning eradication of Swine Dysentery on their farms and has the intention of generating data to establish a basis for decision-making regarding future eradications. A structured survey was conducted on 68 Swiss pig farms where an eradication of Swine Dysentery had already taken place. Read More

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http://dx.doi.org/10.17236/sat00202DOI Listing
April 2019
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The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets.

Viruses 2019 Mar 30;11(4). Epub 2019 Mar 30.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.

Transmissible gastroenteritis virus (TGEV) is the etiologic agent of transmissible gastroenteritis in pigs, and the N-terminal domain of TGEV spike protein is generally recognized as both the virulence determinant and enteric tropism determinant. Here, we assembled a full-length infectious cDNA clone of TGEV in a bacterial artificial chromosome. Using a novel approach, the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) systems efficiently and rapidly rescued another recombinant virus with a 224-amino-acid deletion in the N-terminal domain of the TGEV gene (S_NTD224), which is analogous to the N-terminal domain of porcine respiratory coronavirus. Read More

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http://dx.doi.org/10.3390/v11040313DOI Listing
March 2019
2 Reads

Manganese-Induced Substrate Promiscuity in the Reaction Catalyzed by Phosphoglutamine Cytidylyltransferase from Campylobacter jejuni.

Biochemistry 2019 Apr 9;58(16):2144-2151. Epub 2019 Apr 9.

Department of Biochemistry & Biophysics , Texas A&M University , College Station , Texas 77843 , United States.

The leading cause of bacterial gastroenteritis, Campylobacter jejuni, is a Gram-negative pathogen that contains a unique O-methyl phosphoramidate (MeOPN) on its capsular polysaccharide. Previously, MeOPN has been linked to the evasion of host immune responses and serum resistance. Despite the involvement of MeOPN in pathogenicity, the complete biosynthesis of this modification is unknown; however, the first four enzymatic steps have been elucidated. Read More

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http://dx.doi.org/10.1021/acs.biochem.9b00189DOI Listing
April 2019
1 Read

Multiple eruptive ulcers in a patient with quiescent ulcerative colitis.

BMJ 2019 Mar 28;364:l847. Epub 2019 Mar 28.

St Helier Hospital, Carshalton, UK.

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http://dx.doi.org/10.1136/bmj.l847DOI Listing
March 2019
1 Read

Clostridium difficile-associated diarrhea following the therapy with antibiotic and proton pump inhibitors in a 77-year-old man with several comorbidities: A case report.

Medicine (Baltimore) 2019 Mar;98(13):e15004

Department of Pharmacy.

Rationale: Clostridium difficile-associated diarrhea (CDAD) remains a persistent challenge, with substantially increased incidence and severity. The rising burden of CDAD requires urgent identification of preventable risk factors.

Patients Concerns: A 77-year-old man with the symptoms of abdominal pain and watery diarrhea was readmitted to the hospital, who received cephalosporins and proton pump inhibitors (PPIs) during the initial hospitalization for 12 days until discharge. Read More

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http://dx.doi.org/10.1097/MD.0000000000015004DOI Listing
March 2019
1 Read

Novel narrow spectrum benzyl thiophene sulfonamide derivatives to control Campylobacter.

J Antibiot (Tokyo) 2019 Mar 27. Epub 2019 Mar 27.

Food Animal Health Research Program, Department of Veterinary Preventive Medicine, The Ohio State University, OARDC, Wooster, OH, USA.

Campylobacter is a leading cause of bacterial foodborne gastroenteritis worldwide, and poultry are a major source of human campylobacteriosis. The control of Campylobacter from farm to fork is challenging due to emergence of microbial resistance and lack of effective control methods. We identified a benzyl thiophene sulfonamide based small molecule (compound 1) with a minimal inhibitory concentration (MIC) of 100 μM against Campylobacter jejuni 81-176 and Campylobacter coli ATCC33559, good drug-like properties, and low toxicity on eukaryotic cells. Read More

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http://dx.doi.org/10.1038/s41429-019-0168-xDOI Listing
March 2019
1 Read
2.041 Impact Factor

Increased growth rate and amikacin resistance of Salmonella enteritidis after one-month spaceflight on China's Shenzhou-11 spacecraft.

Microbiologyopen 2019 Mar 25:e833. Epub 2019 Mar 25.

Nankai University School of Medicine, Tianjin, China.

China launched the Tiangong-2 space laboratory in 2016 and will eventually build a basic space station by the early 2020s. These spaceflight missions require astronauts to stay on the space station for more than 6 months, and they inevitably carry microbes into the space environment. It is known that the space environment affects microbial behavior, including growth rate, biofilm formation, virulence, drug resistance, and metabolism. Read More

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http://dx.doi.org/10.1002/mbo3.833DOI Listing
March 2019
1 Read

Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.

Virulence 2019 Dec;10(1):248-259

b Beijing Key Laboratory of Animal Genetic Improvement, College of Animal Science and Technology , China Agricultural University , Beijing , China.

With a broad range of hosts, Salmonella enterica serovar Typhimurium (S. Typhimurium) is the major cause of gastroenteritis in human beings and systemic disease in susceptible mice strains. However, different S. Read More

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http://dx.doi.org/10.1080/21505594.2019.1597496DOI Listing
December 2019
1 Read

Retrospective study showed that bacterial gastroenteritis was an important cause of bloody stools in newborn infants.

Acta Paediatr 2019 Mar 21. Epub 2019 Mar 21.

Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Aim: Acute bacterial gastroenteritis is a major cause of morbidity and mortality, especially in the developing countries. We examined the incidence, clinical features and outcomes in the first week of life.

Methods: This was a retrospective study of culture-proven bacterial gastroenteritis in newborn infants that were diagnosed between January 2011 and September 2018 in a tertiary centre in Israel. Read More

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http://dx.doi.org/10.1111/apa.14787DOI Listing
March 2019
2 Reads

Characterization of conditions for bacteria-human norovirus capsid P protein complex (BPC) binding to and removal from Romaine lettuce extract.

Int J Food Microbiol 2019 Jun 12;298:11-19. Epub 2019 Mar 12.

Department of Bioengineering, Shanghai Institute of Technology, 100 Haiquan Rd, Fengxian District, Shanghai 201418, China. Electronic address:

Norovirus is a very contagious virus that causes acute gastroenteritis. Contaminated produce is a main vehicle for dissemination of human noroviruses (HuNoVs). As HuNoVs could bind to bacteria effectively, it is highly possible that produce could be contaminated by bacteria-HuNoVs complex. Read More

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http://dx.doi.org/10.1016/j.ijfoodmicro.2019.03.008DOI Listing
June 2019
2 Reads

Population structure and genetic diversity of Vibrio parahaemolyticus from a coastal area of China based on a multi-locus sequence typing (MLST) scheme.

Antonie Van Leeuwenhoek 2019 Mar 15. Epub 2019 Mar 15.

Department of Central Lab, Weihai Municipal Hospital Affiliated to Dalian Medical University, Weihai, 264200, Shandong, People's Republic of China.

The Gram-negative marine bacterium Vibrio parahaemolyticus has been identified as a major cause of bacterial food poisoning in China. Here, the population structure and genetic diversity of V. parahaemolyticus from Weihai, a coastal city in China, was studied by the multi-locus sequence typing (MLST) method. Read More

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http://dx.doi.org/10.1007/s10482-019-01252-0DOI Listing
March 2019
2 Reads

The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan.

Epidemiol Infect 2019 Jan;147:e134

Veterinary Epidemiology, Economics and Public Health Group,The Royal Veterinary College,Hawkshead Lane, North Mymms, AL9 7TA, Hatfield,UK.

Campylobacter is the leading cause of foodborne bacterial gastroenteritis in humans worldwide, often associated with the consumption of undercooked poultry. In Jordan, the majority of broiler chicken production occurs in semi-commercial farms, where poor housing conditions and low bio-security are likely to promote campylobacter colonisation. While several studies provided estimates of the key parameters describing the within-flock transmission dynamics of campylobacter in typical high-income countries settings, these data are not available for Jordan and Middle-East in general. Read More

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http://dx.doi.org/10.1017/S0950268818003308DOI Listing
January 2019
3 Reads

Proteotyping as alternate typing method to differentiate Campylobacter coli clades.

Sci Rep 2019 Mar 12;9(1):4244. Epub 2019 Mar 12.

Institut für Medizinische Mikrobiologie, Universitätsmedizin Göttingen, Kreuzbergring 57, 37075, Göttingen, Germany.

Besides Campylobacter jejuni, Campylobacter coli is the most common bacterial cause of gastroenteritis worldwide. C. coli is subdivided into three clades, which are associated with sample source. Read More

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http://www.nature.com/articles/s41598-019-40842-w
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http://dx.doi.org/10.1038/s41598-019-40842-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414644PMC
March 2019
4 Reads

Host genotype and early life microbiota alterations have additive effects on disease susceptibility.

Mucosal Immunol 2019 05 11;12(3):586-588. Epub 2019 Mar 11.

Department of Microbiology, NYU Langone Medical Center, New York, NY, USA.

Why do people develop chronic inflammatory illnesses, such as inflammatory bowel disease and auto-immunity, when they are adults? Is the trigger a recent exposure or may the seeds of the problem have formed much earlier in life? What is the role of genetic susceptibility in such processes?In this issue of Mucosal Immunology, Goethel et al. (Mucosal Immunol. 1, 2019) developed an experimental system in mice to provide at least partial answers to these important questions, in a model relevant to inflammatory bowel disease (IBD). Read More

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http://www.nature.com/articles/s41385-019-0157-1
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http://dx.doi.org/10.1038/s41385-019-0157-1DOI Listing
May 2019
8 Reads

[Characterization of Salmonella Heidelberg strains isolated in Chile].

Rev Med Chil 2019 ;147(1):24-33

Laboratorio de Bacteriología, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, España.

Background: Salmonella Heidelberg (S. Heidelberg) causes gastroenteritis and sometimes bacteremia and endocarditis. In other countries, this serovar has multidrug resistance including extended-spectrum β-lactamases (ESBLs) and AmpC (β-lactamases (AmpC), associated with the blaCMY-2 gene. Read More

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http://dx.doi.org/10.4067/S0034-98872019000100024DOI Listing
March 2019
5 Reads

In vitro efficacy of potentiated egg yolk powder against Campylobacter jejuni does not correlate with in vitro efficacy.

PLoS One 2019 7;14(3):e0212946. Epub 2019 Mar 7.

Chaire de Recherche industrielle du CRSNG en salubrité des viandes, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Campylobacter jejuni is a zoonotic agent responsible for the foodborne gastroenteritis campylobacteriosis. Control of C. jejuni load in the poultry primary production is recognized as an avenue to reduce human exposure to the pathogen. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405129PMC
March 2019
6 Reads

Specific Interactions between Human Norovirus and Environmental Matrices: Effects on the Virus Ecology.

Viruses 2019 Mar 5;11(3). Epub 2019 Mar 5.

Department of Civil and Environmental Engineering, Graduate School of Engineering, Tohoku University, Aoba 6-6-06, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579, Japan.

Human norovirus is the major cause of non-bacterial epidemic gastroenteritis. Human norovirus binds to environmental solids via specific and non-specific interactions, and several specific receptors for human norovirus have been reported. Among them, histo-blood group antigens (HBGA) are the most studied specific receptor. Read More

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http://dx.doi.org/10.3390/v11030224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466409PMC
March 2019
2 Reads

A Lactic Acid Bacteria (LAB)-Based Vaccine Candidate for Human Norovirus.

Viruses 2019 Mar 2;11(3). Epub 2019 Mar 2.

Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA.

Human noroviruses (HuNoVs) are responsible for more than 95% of the non-bacterial acute gastroenteritis epidemics in the world. The CDC estimates that every year 21 million individuals suffer from HuNoV-induced gastroenteritis in the United States. Currently, there is no FDA-approved vaccine for HuNoVs. Read More

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http://dx.doi.org/10.3390/v11030213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466309PMC
March 2019
1 Read

Immunization with subunits of a novel pilus produced by virulent Clostridium perfringens strains confers partial protection against necrotic enteritis in chickens.

Vet Microbiol 2019 Mar 7;230:7-13. Epub 2019 Jan 7.

Guelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario N1G 5C9, Canada. Electronic address:

Necrotic enteritis (NE) is an economically important disease of broiler chickens that is caused primarily by Clostridium perfringens strains that produce the NetB toxin. It is controlled in North America principally through the application of in-feed antimicrobials, but alternative control methods, such as vaccination, are urgently needed. We previously identified a cluster of C. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.01.005DOI Listing
March 2019
4 Reads

Duration of antibiotic treatment for common infections in English primary care: cross sectional analysis and comparison with guidelines.

BMJ 2019 02 27;364:l440. Epub 2019 Feb 27.

Modelling and Economics Unit, National Infection Service, Public Health England, London NW9 5EQ, UK.

Objective: To evaluate the duration of prescriptions for antibiotic treatment for common infections in English primary care and to compare this with guideline recommendations.

Design: Cross sectional study.

Setting: General practices contributing to The Health Improvement Network database, 2013-15. Read More

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http://dx.doi.org/10.1136/bmj.l440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391655PMC
February 2019
2 Reads

Cuts Both Ways: Proteases Modulate Virulence of Enterohemorrhagic .

MBio 2019 02 26;10(1). Epub 2019 Feb 26.

Department of Pathology, Microbiology, and Immunology and the Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Enterohemorrhagic (EHEC) is a major cause of foodborne gastrointestinal illness. EHEC uses a specialized type III secretion system (T3SS) to form attaching and effacing lesions in the colonic epithelium and outcompete commensal gut microbiota to cause disease. A recent report in (E. Read More

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http://mbio.asm.org/lookup/doi/10.1128/mBio.00115-19
Publisher Site
http://dx.doi.org/10.1128/mBio.00115-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391915PMC
February 2019
5 Reads

Role of putative virulence traits of Campylobacter jejuni in regulating differential host immune responses.

J Microbiol 2019 Apr 22;57(4):298-309. Epub 2019 Feb 22.

Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India.

Among the major enteric pathogens, Campylobacter jejuni is considered an important source of diarrheal illness in humans. In contrast to the acute gastroenteritis in humans, C. jejuni exhibits prolonged cecal colonization at a high level with little or no pathology in chickens. Read More

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http://dx.doi.org/10.1007/s12275-019-8165-0DOI Listing
April 2019
1 Read

CHARACTERIZATION OF ENTEROAGGREGATIVE ESCHERICHIA COLI AMONG DIARRHEAL CHILDRENIN WESTERN BRAZILIAN AMAZON.

Arq Gastroenterol 2018 Oct-Dec;55(4):390-396

Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil.

Background: Enteroaggregative Escherichia coli (EAEC) is one of the main acute and chronic diarrhea causes both in children and adults, mainly in developing countries.

Objective: The aim of the present study is to characterize EAEC strains isolated from faecal samples and to identify genes potentially contributing to virulence, biofilm production and antimicrobial resistance in children admitted to a pediatric hospital in Porto Velho, Rondônia State.

Methods: The total of 1,625 E. Read More

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http://dx.doi.org/10.1590/S0004-2803.201800000-84DOI Listing
March 2019
1 Read

Evaluation of the impact of shigellosis exclusion policies in childcare settings upon detection of a shigellosis outbreak.

BMC Infect Dis 2019 Feb 19;19(1):172. Epub 2019 Feb 19.

National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, H24-11, Atlanta, GA, 30329-4027, USA.

Background: In the event of a shigellosis outbreak in a childcare setting, exclusion policies are typically applied to afflicted children to limit shigellosis transmission. However, there is scarce evidence of their impact.

Methods: We evaluated five exclusion policies: Children return to childcare after: i) two consecutive laboratory tests (either PCR or culture) do not detect Shigella, ii) a single negative laboratory test (PCR or culture) does not detect Shigella, iii) seven days after beginning antimicrobial treatment, iv) after being symptom-free for 24 h, or v) 14 days after symptom onset. Read More

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http://dx.doi.org/10.1186/s12879-019-3796-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379933PMC
February 2019
2 Reads

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis-Reply.

JAMA 2019 02;321(7):707-708

Department of Biostatistics, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1001/jama.2018.19595DOI Listing
February 2019
1 Read

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis.

JAMA 2019 02;321(7):706

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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http://dx.doi.org/10.1001/jama.2018.19591DOI Listing
February 2019
1 Read

Long-term Follow-up of Antibiotics vs Surgery for Appendicitis.

Authors:
Nicholas L Syn

JAMA 2019 02;321(7):706-707

Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1001/jama.2018.19588DOI Listing
February 2019
2 Reads
47.661 Impact Factor

Genome characterization and temporal evolution analysis of a non-epidemic norovirus variant GII.8.

Infect Genet Evol 2019 Jun 15;70:15-23. Epub 2019 Feb 15.

Guangdong Institute of Microbiology, State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou 510070, PR China. Electronic address:

Noroviruses are the primary cause of non-bacterial acute gastroenteritis worldwide, and GII.8 belongs to a non-epidemic genotype with a limited understanding currently. In this study, we assembled the first GII. Read More

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http://dx.doi.org/10.1016/j.meegid.2019.02.010DOI Listing
June 2019
2 Reads

Taxonomy, virulence genes and antimicrobial resistance of Aeromonas isolated from extra-intestinal and intestinal infections.

BMC Infect Dis 2019 Feb 14;19(1):158. Epub 2019 Feb 14.

Center of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

Background: Clinical characteristics (taxonomy, virulence genes and antimicrobial resistance ) of Aeromonas in isolated from extra-intestinal and intestinal infections were investigated to describe epidemiology, associated virulence factors and optimal therapy options.

Methods: Clinical samples (n = 115) of Aeromonas were collected from a general hospital in Beijing between the period 2015 and 2017. Taxonomy was investigate by Multilocus phylogenetic analysis (MLPA), 10 putative virulence factors by use of polymerase chain reaction (PCR) and antimicrobial resistance to 15 antibiotics by use of the microbroth dilution method. Read More

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http://dx.doi.org/10.1186/s12879-019-3766-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376669PMC
February 2019
1 Read

Comparative Evaluation of Seegene Allplex Gastrointestinal, Luminex xTAG Gastrointestinal Pathogen Panel, and BD MAX Enteric Assays for Detection of Gastrointestinal Pathogens in Clinical Stool Specimens.

Arch Pathol Lab Med 2019 Feb 14. Epub 2019 Feb 14.

From the Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea (Drs Yoo, J. Park, H. K. Lee, and Y.-J. Park); the Department of Laboratory Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Korea (Mss Yu and K. G. Park and Mr G. D. Lee); and the Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge (Ms Oak).

Context.—: Infectious gastroenteritis is caused by various pathogens, including bacteria, viruses, and parasites.

Objective. Read More

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http://dx.doi.org/10.5858/arpa.2018-0002-OADOI Listing
February 2019
1 Read

An Abdominal Aortic Aneurysm, Intramural Thrombus and Moderate Leak in an Asian Man Presenting with Acute Gastroenteritis.

Eur J Case Rep Intern Med 2018 31;5(1):000758. Epub 2018 Jan 31.

Emergency Department, IMC Hospital, Jeddah, Saudi Arabia.

Introduction: Missing a leaking abdominal aortic aneurysm (AAA) is common in medical practice because few at-risk patients have a history of AAA and many have an unusual presentation.

Background: AAA is less common among Asians than white Caucasians of the same age. Our patient had no significant risk factors apart from age and sex and had an unusual presentation. Read More

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http://dx.doi.org/10.12890/2017_000759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346940PMC
January 2018
1 Read

A High Prevalence of Gastrointestinal Manifestations in Common Variable Immunodeficiency.

Am J Gastroenterol 2019 Apr;114(4):648-655

Department of Gastroenterology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Objectives: Common variable immunodeficiency (CVID) is associated with a spectrum of autoimmune complications. We studied the prevalence of gastrointestinal (GI) manifestations and infections in patients with CVID.

Methods: Complete clinical data of 132 Finnish patients with CVID (106 probable and 26 possible CVID) followed up between 2007 and 2016 were collected to a structured database. Read More

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http://dx.doi.org/10.14309/ajg.0000000000000140DOI Listing
April 2019
3 Reads

Monitoring Complications of Medically Managed Acute Appendicitis.

Am Surg 2018 Oct;84(10):1684-1690

Department of Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.

Nonoperative management of acute appendicitis is becoming widespread, but recurrence and the potential for a complicated course are important concerns. An admission report-based institutional database was created to monitor appendicitis treatment outcomes. Complications and complexity of surgery were recorded based on manual chart review. Read More

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October 2018
1 Read

Risk factors for contagious gastroenteritis in adult patients with diarrhoea in the emergency department - a prospective observational multicentre study.

BMC Infect Dis 2019 Feb 11;19(1):133. Epub 2019 Feb 11.

Focused Research Unit in Emergency Medicine, Hospital of Southern Denmark, Kresten Philipsens Vej 15, DK-6200, Aabenraa, Denmark.

Background: Infectious gastroenteritis is common in the emergency department (ED). Patients infected with either Norovirus or toxigenic Clostridium difficile require special isolation procedures. The aims were to describe the aetiology of infectious gastroenteritis in the ED, evaluate whether current isolation procedures, based on clinical judgement are sufficient, and to identify information that might be used to identify patients requiring isolation. Read More

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http://dx.doi.org/10.1186/s12879-019-3754-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371479PMC
February 2019
1 Read

Antibiotics for induction and maintenance of remission in Crohn's disease.

Cochrane Database Syst Rev 2019 Feb 7;2:CD012730. Epub 2019 Feb 7.

Department of Medicine, University of Western Ontario, London, ON, Canada.

Background: Several antibiotics have been evaluated in Crohn's disease (CD), however randomised controlled trials (RCTs) have produced conflicting results.

Objectives: To assess the efficacy and safety of antibiotics for induction and maintenance of remission in CD.

Search Methods: We searched MEDLINE, Embase, CENTRAL, the Cochrane IBD Group Specialized Register and Clinicaltrials. Read More

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http://dx.doi.org/10.1002/14651858.CD012730.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366891PMC
February 2019
11 Reads

Differentiating Acute Food Protein-Induced Enterocolitis Syndrome From Its Mimics: A Comparison of Clinical Features and Routine Laboratory Biomarkers.

J Allergy Clin Immunol Pract 2019 Feb 25;7(2):471-478.e3. Epub 2018 Oct 25.

Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia; Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.

Background: Food protein-induced enterocolitis syndrome (FPIES) is frequently misdiagnosed and subject to diagnostic delay. Profuse vomiting, the cardinal feature of acute FPIES, may occur in more common pediatric disorders such as gastroenteritis and sepsis.

Objectives: We sought to determine differentiating features at acute presentation between FPIES, gastroenteritis, and sepsis in young children presenting to an emergency department (ED) with profuse vomiting. Read More

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http://dx.doi.org/10.1016/j.jaip.2018.10.020DOI Listing
February 2019
5 Reads

Extensive drug resistant Salmonella enterica serovar Senftenberg carrying bla encoding plasmid p5558 (IncA/C) from India.

Pathog Glob Health 2019 02 6;113(1):20-26. Epub 2019 Feb 6.

a Department of Clinical Microbiology , Christian Medical College and Hospital , Vellore , India.

Non-typhoidal Salmonella (NTS) are foodborne pathogens that are responsible for self-limiting gastroenteritis in humans. The present study aims at the molecular characterisation and comparative genomics of Salmonella enterica serovar Senftenberg strain P5558 isolated from the pus samples of a patient suffering from stump infection. The isolate was subjected to serotyping and antimicrobial susceptibility test to understand the phenotypical characteristics. Read More

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http://dx.doi.org/10.1080/20477724.2019.1574112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427686PMC
February 2019
1 Read

Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties.

Nutrients 2019 Feb 2;11(2). Epub 2019 Feb 2.

Dipartimento di Scienze Biomediche e Chirurgiche, Università di Perugia, 06123 Perugia, Italy.

A growing body of evidence suggests that probiotic functionality is not accurately predicted by their taxonomy. Here, we have set up a study to investigate the effectiveness of two probiotic formulations containing a blend of seven bacterial species in modulating intestinal inflammation in two rodent models of colitis, induced by treating mice with 2,4,6-Trinitrobenzenesulfonic acid (TNBS) or dextran sodium sulfate (DSS). Despite the taxonomy of the bacterial species in the two probiotic formulations being similar, only one preparation (Blend 2-Vivomixx) effectively attenuated the development of colitis in both models. Read More

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http://dx.doi.org/10.3390/nu11020325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412585PMC
February 2019
8 Reads

Rapid and specific detection of Salmonella infections using chemically modified nucleic acid probes.

Anal Chim Acta 2019 Apr 21;1054:157-166. Epub 2018 Dec 21.

Department of Physics, Chemistry and Biology, Linkӧping University, Linköping, 58185, Sweden; Wallenberg Centre for Molecular Medicine (WCMM), Linköping University, Linköping, Sweden. Electronic address:

Salmonella is a leading source of bacterial foodborne illness in humans, causing gastroenteritis outbreaks with bacteraemia occurrences that can lead to clinical complications and death. Eggs, poultry and pig products are considered as the main carriers of the pathogenic Salmonella for humans. To prevent this relevant zoonosis, key changes in food safety regulations were undertaken to improve controls in the food production chain. Read More

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http://dx.doi.org/10.1016/j.aca.2018.12.027DOI Listing
April 2019
4 Reads
4.513 Impact Factor

Age-specific gastrointestinal parasite shedding in free-ranging cheetahs (Acinonyx jubatus) on Namibian farmland.

Parasitol Res 2019 Mar 31;118(3):851-859. Epub 2019 Jan 31.

Department of Evolutionary Ecology, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany.

The cheetah (Acinonyx jubatus Brookes 1828) is classified as "vulnerable" by the International Union for Conservation of Nature (IUCN). Threats to cheetah populations are a decrease of suitable habitats, an increase of conflicts with livestock farmers and potentially pathogens. While there is some information on the viral and bacterial pathogens circulating in cheetah populations, information on gastrointestinal parasites is scarce. Read More

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http://dx.doi.org/10.1007/s00436-018-6190-2DOI Listing
March 2019
1 Read

Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.

PLoS Pathog 2019 01 31;15(1):e1007468. Epub 2019 Jan 31.

Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati OH, United States of America.

Helicobacter pylori (H. pylori) is the major risk factor for the development of gastric cancer. Our laboratory has reported that the Sonic Hedgehog (Shh) signaling pathway is an early response to infection that is fundamental to the initiation of H. Read More

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http://dx.doi.org/10.1371/journal.ppat.1007468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380601PMC
January 2019
5 Reads

Whole-genome sequencing of the rare Salmonella enterica serovar Anfo isolated from food handlers.

J Med Microbiol 2019 Mar 30;68(3):429-431. Epub 2019 Jan 30.

1 National Public Health Laboratory, Ministry of Health, Singapore.

Field investigations were conducted after a small cluster of food poisoning involving six cases was reported. While no stool samples were available from the cases for microbiological testing, Salmonella species was found to be present in the stools of food handlers with gastroenteritis symptoms. Four Salmonella isolates recovered from the food handlers were retrospectively investigated at the genome level using whole-genome sequencing (WGS). Read More

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http://dx.doi.org/10.1099/jmm.0.000934DOI Listing
March 2019
3 Reads

Risk factors for upper and lower functional gastrointestinal disorders in Persian Gulf War Veterans during and post-deployment.

Neurogastroenterol Motil 2019 Mar 29;31(3):e13533. Epub 2019 Jan 29.

Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana.

Background: Gastroenteritis is a risk factor for irritable bowel syndrome (IBS), but its role in other functional gastrointestinal disorders (FGIDs) is less clear. The aim of this study was to determine the prevalence of FGIDs in Gulf War (GW) Veterans before, during, and after deployment and to determine whether gastroenteritis was a risk factor for upper and lower FGIDs.

Methods: The Veterans who served during the Persian GW were mailed validated questionnaires inquiring about their bowel habits, psychological and extra-intestinal symptoms, and quality of life (QOL). Read More

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http://doi.wiley.com/10.1111/nmo.13533
Publisher Site
http://dx.doi.org/10.1111/nmo.13533DOI Listing
March 2019
11 Reads

Mixed Viral-Bacterial Infections and Their Effects on Gut Microbiota and Clinical Illnesses in Children.

Sci Rep 2019 Jan 29;9(1):865. Epub 2019 Jan 29.

Biomedical Research Center, Qatar University, Doha, 2713, Qatar.

Acute gastroenteritis remains a major cause of morbidity and mortality among young children worldwide. It accounts for approximately 1.34 million deaths annually in children younger than five years. Read More

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http://dx.doi.org/10.1038/s41598-018-37162-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351549PMC
January 2019
3 Reads
5.078 Impact Factor