28,661 results match your criteria Gastritis and Peptic Ulcer Disease
Surg Laparosc Endosc Percutan Tech 2018 Dec 4. Epub 2018 Dec 4.
Departments of General Surgery.
Background: Laparoscopic sleeve gastrectomy (LSG) has become more popular among other bariatric procedures. The histopathologic changes in the sleeve gastrectomy specimens have not been widely investigated among the Turkish population.
Objective: The purpose of this study was to delineate these histopathologic findings of the LSG specimens of morbidly obese patients from a single center. Read More
Am J Physiol Gastrointest Liver Physiol 2018 Dec 6. Epub 2018 Dec 6.
Murdoch Childrens Research Institute, Australia.
Expression of the cytokine IL-11 is elevated in human Helicobacter pylori infection and progressively increases with worsening gastric pathology. Additionally, IL-11 is required for tumour development in STAT3 dependent murine models of gastric cancer (GC) and, when administered acutely, causes resolving atrophic gastritis. However, it is unclear whether locally elevated IL-11 ligand expression can, in isolation from oncogenic gp130-JAK-STAT pathway mutations, initiate GC pathogenesis. Read More
Cureus 2018 Sep 14;10(9):e3306. Epub 2018 Sep 14.
Medicine, Xavier University School of Medicine, Oranjestad, ABW.
Pernicious anemia (also known as Biermer's disease) is an autoimmune atrophic gastritis which predominantly affects the fundus of the stomach. It results in a deficiency of vitamin B12 (cobalamin) as it affects the normal process of absorption in the ileum. The pernicious anemia is characterized by a wide range of hematological and neurological features. Read More
Gastroenterology 2018 Nov 30. Epub 2018 Nov 30.
Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan; AMED-CREST, AMED, Japan Agency for Medical Research and Development, Tokyo, Japan; WPI Nano-Life Science Institute (Nano-LSI), Kanazawa University, Kanazawa, Japan. Electronic address:
Background & Aims: Gastritis is associated with development of stomach cancer, but little is known about changes in microRNA expression patterns during gastric inflammation. Specific changes in gene expression in epithelial cells are difficult to monitor due to the heterogeneity of the tissue. We investigated epithelial cell-specific changes in microRNA expression during gastric inflammation and gastritis-associated carcinogenesis in mice. Read More
Eur J Cancer Prev 2019 Jan;28(1):58
School of Surgery, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Semin Hematol 2018 Oct 7;55(4):256-261. Epub 2018 Aug 7.
Division of Gastroenterology and Hepatology, Medical University of Vienna, Austria; Loha for life, Center of Excellence for Iron Deficiency, Vienna, Austria. Electronic address:
Iron deficiency (ID) workup is a common challenge for gastrointestinal endoscopy. In premenopausal women current guidelines recommend serologic evaluation of coeliac disease only. Here we systematically tested serologic screening for autoimmune gastritis (AIG) in a large cohort of patients with ID. Read More
Helicobacter 2018 Dec 4:e12559. Epub 2018 Dec 4.
Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan.
Background: Previously, we conducted an epidemiological study screening for Helicobacter pylori antibody positivity among Japanese junior high school students. In this study, we updated the epidemiological data and assessed the clinical features of H pylori antibody-positive junior high school students.
Materials And Methods: We assessed H pylori antibody-positive subjects who were identified between 2012 and 2015 at four junior high schools in Nagano Prefecture, Japan. Read More
Sci Rep 2018 Dec 4;8(1):17616. Epub 2018 Dec 4.
Hebrew University-Hadassah School of Public Health and Community Medicine, Jerusalem, Israel.
Associations observed of Helicobacter pylori infection with haemoglobin levels are inconsistent. We examined associations of H. pylori sero-prevalence and serum pepsinogens (PGs), as non-invasive markers of atrophic gastritis, with haemoglobin levels. Read More
Int J Mol Sci 2018 Dec 3;19(12). Epub 2018 Dec 3.
Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.
Background: Our aim was to evaluate the feasibility of a serological assessment of gastric cancer risk in patients undergoing colonoscopy in countries with low-to-moderate incidence rates.
Methods: Serum samples were prospectively collected from 453 patients (>50 years old) undergoing colonoscopies. Of these, 279 (61. Read More
Molecules 2018 Nov 30;23(12). Epub 2018 Nov 30.
College of Food Science and Engineering, Jilin University, Changchun 130062, China.
(HE) is a well-known edible and medicinal fungus widely grown in Asian countries. Polysaccharides from the (HEP) are major biological macromolecules. It has been reported that HEP has multiple biological activities, such as antioxidant activity, immunomodulatory effects, anti-inflammatory effect, anti-chronic gastritis activity, and so on. Read More
J Pathol 2018 Dec 3. Epub 2018 Dec 3.
Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri, USA.
Chronic inflammation of the gastric mucosa, often caused by autoimmune gastritis and/or infection with Helicobacter pylori, can lead to atrophy of acid-secreting parietal cells with metaplasia of remaining cells. The histological pattern marks a critical step in the progression from chronic gastritis to gastric cancer, yet underlying mechanism(s) of inflammation-induced cell death of gastric epithelial cells are poorly understood. We investigated direct effects of a type 1 cytokine associated with autoimmunity and infection, interferon-γ (IFN-γ), on gastric epithelial cells. Read More
Case Rep Gastrointest Med 2018 30;2018:7091520. Epub 2018 Oct 30.
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.
In this report, we described two patients with white globe appearance in autoimmune atrophic gastritis. Endoscopy revealed multiple white substances in the stomach in both cases. Biopsied specimens from the lesions contained dilated glands and showed a decrease in parietal cells. Read More
Arab J Gastroenterol 2018 Nov 30. Epub 2018 Nov 30.
Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address:
Background And Study Aims: Helicobacter pylori (H. pylori) has been implicated in the pathogenesis of most important gastro-duodenal diseases, such as gastritis, peptic ulcer disease (PUD) and gastric cancer. H. Read More
J Pediatr Surg 2018 Nov 6. Epub 2018 Nov 6.
Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China. Electronic address:
Objective: Helicobacter pylori infection is common among Asians. However, evidence in the recent years has demonstrated a decrease in the prevalence of H. pylori infection among children and adults worldwide. Read More
Lond Med Phys J 1816 Jan;35(203):14-19
Med Phys J 1814 Jan;31(179):1-5
Med Phys J 1813 Jun;29(172):454
Med Phys J 1806 Dec;16(94):535-538
Med Phys J 1800 Mar;3(13):229-231
JGH Open 2018 Jun 25;2(3):80-86. Epub 2018 Mar 25.
Second Department of Internal Medicine Wakayama Medical University Wakayama Japan.
Background And Aim: Nodular gastritis is caused by infection and is associated with the development of diffuse-type gastric cancer. This study examined the clinical characteristics of patients with nodular gastritis, including cancer incidence before and after H. pylori eradication. Read More
MBio 2018 Nov 27;9(6). Epub 2018 Nov 27.
Pathogen Biology Laboratory, Department of Biotechnology and Bioinformatics, University of Hyderabad, Hyderabad, India
Infection of the human stomach caused by is very common, as the pathogen colonizes more than half of the world's population. It is associated with varied outcomes of infection, such as peptic ulcer disease, gastric ulcers, and mucosa-associated lymphoid tissue lymphoma, and is generally considered a risk factor for the development of gastric adenocarcinoma. Cholesteryl glucosides (CGs) constitute a vital component of the cell wall of and contribute to its pathogenicity and virulence. Read More
Pediatr Neonatol 2018 Oct 2. Epub 2018 Oct 2.
Division of Pediatric Emergency, Department of Emergency, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Ph.D. Program in Translational Medicine, Graduate Institute of Clinical Medicine, 18 Kaohsiung Medical University and Academia Sinica, Taiwan; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:
Background: No previous studies have explored emergency medical care for children with chronic neuromuscular disorders (NMDs). We aimed to determine the major reasons for the emergency room (ER) readmission of pediatric patients with NMDs and suggest changes to the care plan to decrease readmissions.
Methods: Children with chronic NMDs (aged <18 years) who visited a medical center-based ER between January 2005 and January 2015 were included. Read More
Invest Ophthalmol Vis Sci 2018 Nov;59(14):DES151-DES156
Department of Ophthalmology, Toho University Graduate School of Medicine, Tokyo, Japan.
Mucins, which play important roles on the ocular surface in wettability, lubrication, and barrier function, are classified into two categories: secreted mucins and membrane-associated mucins. The most important secreted mucin on the ocular surface is MUC5AC, which is secreted by the conjunctival goblet cells. In the human conjunctiva, goblet cells are present in higher concentrations in the fornix, inferior nasal bulbar, and the lid wiper on the lid margin. Read More
Protein Cell 2018 Nov 26. Epub 2018 Nov 26.
MOE Key Laboratory of Bioinformatics and TCM-X center/Bioinformatics Division, BNRist/Department of Automation, Tsinghua University, Beijing, 100084, China.
The development of gastritis is associated with an increased risk of gastric cancer. Current invasive gastritis diagnostic methods are not suitable for monitoring progress. In this work based on 78 gastritis patients and 50 healthy individuals, we observed that the variation of tongue-coating microbiota was associated with the occurrence and development of gastritis. Read More
J Food Sci 2018 Nov 23. Epub 2018 Nov 23.
Dept. of Biological Science and Technology, China Medical Univ., Taichung, 40402, Taiwan.
Helicobacter pylori infection is associated with chronic gastritis, peptic ulcers, and gastric cancer. The flavonoid compounds baicalin and baicalein found in many medicinal plants exhibit an anti-inflammatory effect. The administration of Lactobacillus strains reducing the risk of H. Read More
Pathol Oncol Res 2018 Nov 22. Epub 2018 Nov 22.
Department of Pathological Anatomy, School of Medicine, Universidad de La Frontera, Avenida Alemania 0458, Postal Code, 4810296, Temuco, Chile.
Gastric cancer (GC) is the first cancer-related cause of death in Chile; however, no plan for GC early detection has been implemented in this country. The OLGA system characterizes gastritis from stages 0 to IV according to the risk of developing GC based on H. pylori infection, atrophy, metaplasia and GC. Read More
Open Access Maced J Med Sci 2018 Oct 10;6(10):1795-1802. Epub 2018 Oct 10.
Department of Hepato-Gastroenterology, Theodor Bilharz Research Institute, Giza, Egypt.
Background: Globally, gastric cancer (GC) it is the fourth most common cancer and the third cause of cancer-related deaths. Overexpression of MDM2 and B-RAF appeared to be increased in malignancy and associated with poor prognosis in several human tumours, but their role in gastric cancer remains controversial.
Aim: We had investigated the immunohistochemical expression of MDM2 and B-RAF in 136 gastric lesions with/without association. Read More
Front Immunol 2018 5;9:2546. Epub 2018 Nov 5.
Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers in CVID should be defined based on epidemiological data. Risks and mortality for cancers among 455 Italian patients with CVID were compared to cancer incidence data from the Italian Cancer Registry database. Read More
Mol Cell Proteomics 2018 Nov 19. Epub 2018 Nov 19.
Division of Gastroenterology, Vanderbilt University, United States
is the strongest risk factor for gastric cancer. Initial interactions between and its host originate at the microbial-gastric epithelial cell interface, and contact between and gastric epithelium activates signaling pathways that drive oncogenesis. One microbial constituent that increases gastric cancer risk is the pathogenicity island, which encodes a type IV secretion system that translocates the effector protein, CagA, into host cells. Read More
Microbiol Res 2019 Jan 6;218:49-57. Epub 2018 Oct 6.
Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; Immunoregulation Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Electronic address:
Helicobacter pylori (H. pylori) is a bacterial pathogen that resides in more than half of the human population and has co-evolved with humans for more than 58,000 years. This bacterium is orally transmitted during childhood and is a key cause of chronic gastritis, peptic ulcers and two malignant cancers including MALT (mucosa-associated lymphoid tissue) lymphoma and adenocarcinoma. Read More
J Biomed Sci 2018 Nov 19;25(1):84. Epub 2018 Nov 19.
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Background: To develop an individually-tailored dynamic risk assessment model following a multistep, multifactorial process of the Correa's gastric cancer model.
Methods: First, we estimated the state-to-state transition rates following Correa's five-step carcinogenic model and assessed the effect of risk factors, including Helicobacter pylori infection, history of upper gastrointestinal disease, lifestyle, and dietary habits, on the step-by-step transition rates using data from a high-risk population in Matsu Islands, Taiwan. Second, we incorporated information on the gastric cancer carcinogenesis affected by genomic risk factors (including inherited susceptibility and irreversible genomic changes) based on literature to generate a genetic and epigenetic risk assessment model by using a simulated cohort identical to the Matsu population. Read More
Gastroenterology 2018 Nov 16. Epub 2018 Nov 16.
Division of Allergy and Immunology, Department of Pediatrics, University of Cincinnati College of Medicine/Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Clin J Gastroenterol 2018 Nov 16. Epub 2018 Nov 16.
Department of Diagnostic Pathology, Anjo Kosei Hospital, 28 Higashi-hirokute, Anjo-cho, Anjo, Aichi, 446-8602, Japan.
Herein, we describe an extremely rare case of gastritis due to concurrent infection with Epstein-Barr virus (EBV) and cytomegalovirus (CMV) occurring in an immunocompetent adult. The patient was a 35-year-old man who presented with slight fever, nausea, anorexia, weight loss for 3 weeks, mild transaminitis, and leukocytosis with atypical lymphocytes in peripheral blood. The clinical presentation and elevated IgM titers to both EBV-VCA and CMV strongly suggested infectious mononucleosis syndrome caused by co-infection with EBV and CMV. Read More
Helicobacter 2018 Nov 15:e12547. Epub 2018 Nov 15.
Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
Background: Despite recent advances in studies on the gastric microbiome, the role of the non-Helicobacter pylori gastric microbiome in gastric carcinogenesis remains unclear. We evaluated the characteristics of the gastric microbiome and metagenomic functions in patients with IM.
Methods: Participants were classified into six groups according to disease status (chronic superficial gastritis [CSG], intestinal metaplasia [IM], and cancer) and H. Read More
Tunis Med 2018 Jul;96(7):405-410
Chronic gastritis are inflammatory diseases of the gastric mucosa whose diagnosis depends on pathological examination. They are frequent and cover a significant part of the daily activity of pathologists. Their origin is often infectious, particularly by Helicobacter Pylori. Read More
Int J Surg Case Rep 2018 Nov 2;53:214-217. Epub 2018 Nov 2.
Royal Alexandra Hospital, Corsebar Rd, Paisely, PA2 9PN, Scotland, UK. Electronic address:
Introduction: Pneumatosis Intestinalis (PI) can present with a broad range of presentations from chronic and non-specific to acute and life threatening. It is paradoxically one of the few conditions where a pneumoperitoneum found in the diagnostic workup is not necessarily an indication for laparotomy.
Presentation Of Cases: The first case is of a 75 year old gentlemen who attended the emergency department after several weeks of worsening abdominal pain and weight loss. Read More
PLoS One 2018 14;13(11):e0206280. Epub 2018 Nov 14.
School of Public Health, Kunming Medical University, Kunming, CHINA.
Quality of life is an important outcome indicator to evaluate whether treatment is successful or not. Chronic gastritis leads to ongoing deterioration of subjectively perceived quality of life. There are several generic measures, but they are not developed particularly to assess chronic gastritis problems. Read More
PLoS One 2018 14;13(11):e0205644. Epub 2018 Nov 14.
Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia.
The association between gastroesophageal reflux disease (GERD) prevalence and its risk factors in an area with low Helicobacter pylori prevalence is important to clarify. We analyzed the prevalence of GERD and risk factors in an area of Indonesia with low prevalence of H. pylori infection. Read More
J Cell Biochem 2018 Nov 13. Epub 2018 Nov 13.
Department of Gastroenterology, Affiliated Hospital of Jining Medical College, Jining, China.
Gastric cancer (GC) is the second most common cause of cancer death worldwide but could be more curable if diagnosed at an earlier stage. At present, the capability to predict the efficaciousness of molecular diagnosis for GC for each patient remains elusive. The purpose of this study was to identify tumor biomarkers through systems analysis of multigene predictors exploiting the available data resource. Read More
Gastroenterol Hepatol Bed Bench 2018 ;11(4):343-351
Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aim: In this study the significant differentially expressed genes (DEGs) related to gastric cancer (GC) and chronic gastritis were screened to introduce common and distinctive genes between the two diseases.
Background: Diagnosis of gastric cancer as a mortal disease and chronic gastritis the stomach disorder which can be considered as risk factor of GCs required safe and effective molecular biomarkers.
Methods: Microarray profiles were downloaded from Gene Expression Omnibus (GEO) and analyzed via GEO2R. Read More
Gastroenterol Hepatol Bed Bench 2018 ;11(4):333-342
Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Aim: In this research, we designed a direct Enzyme Linked Immunoassay method to detect antigens in stool specimens.
Background: infection as the worldwide problem is related to many gastrointestinal disorders such as gastritis, gastric cancer, non-ulcer disease, peptic ulcer disease and duodenal ulcer.
Methods: We produced and purified recombinant and antigens in and extracted their antibodies from a panel of positive sera specimens. Read More
Curr Rheumatol Rev 2018 Nov 12. Epub 2018 Nov 12.
Joint, bone and connective tissue research center, Golestan University of medical Sciences, Gorgan. Iran.
Background And Aim: Lymphoid cell infiltration and destruction of exocrine glands, specifically lacrimal and salivary glands are characteristics of Sjogren's syndrome (SS). An etiological role has been proposed for Helicobacter pylori (H.Pylori), interacting in the clinical course and complications of SS (including gastric cancer and lymphoma). Read More
J Funct Foods 2018 Jun 21;45:268-276. Epub 2018 Apr 21.
Department of Plant Biology, Rutgers University, New Brunswick, NJ 08901, USA.
Malanga () is used as a medicinal food for infant development and gastritis. We compared the physicochemical properties and gut microbial effects of malanga versus potato () using nutritional analysis, rheometry, TNO Intestinal Model, and C57Bl/6J mouse models. Malanga was characterized by higher starch (70. Read More
Curr Treat Options Gastroenterol 2018 Dec;16(4):605-615
Department of Medicine II, University Hospital, LMU, Munich, Germany.
Purpose: The global prevalence of Helicobacter pylori remains high in spite of its significant downwards trajectory in many regions. The clinical management of H. pylori infection merits guidance to meet ongoing challenges on whom and how to test, prevent, and cure related diseases. Read More
Helicobacter 2018 Nov 9:e12550. Epub 2018 Nov 9.
Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung, Taiwan.
Helicobacter pylori (H. pylori) infection is associated with an inflammatory response in the gastric mucosa, leading to chronic gastritis, peptic ulcers, and gastric cancer. Increased T-cell infiltration is found at sites of H. Read More
J Agric Food Chem 2018 Nov 27. Epub 2018 Nov 27.
Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology , Ghent University , Coupure Links 653 , B-9000 Ghent , Belgium.
Helicobacter pylori gastritis affects gastric pH and concentrations of ascorbic acid, hydrogen peroxide, hypochlorite, ammonia and urea, pepsin, and mucin. First, the separate effects of each of these altered factors on oxidation of pork were investigated during in vitro gastrointestinal digestion. Lipid and protein oxidation increased (range 23-48%) in duodenal digests of pork previously exposed to elevated (6. Read More
J Periodontol 2018 Nov 8. Epub 2018 Nov 8.
Department of Internal Medicine, Gastroenterology, King Fahd Hospital, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Background: There is inconsistent evidence about the association between Helicobacter pylori (H. pylori) and dental diseases with possible effect of environmental factors.
Objective: The aims of the study were to assess (1) the association between gastric and oral H. Read More