8,117 results match your criteria Gastritis and Peptic Ulcer Disease


Attitude and knowledge of Saudi community pharmacists towards use of proton pump inhibitors.

Saudi Pharm J 2019 Feb 7;27(2):225-228. Epub 2018 Nov 7.

Department of Clinical Pharmacy, King Saud University, Saudi Arabia.

Introduction: Proton pump inhibitors (PPIs) effectively suppress acid secretion and play an important role in peptic ulcer disease and gastroesophageal reflux disease There is a real concern about the overutilization of PPIs, which will lead to significant high cost and undesirable outcomes Despite that most of PPIs are classified as prescribed medications, yet most of their users take them without prescription in Saudi Arabia. Therefore, it was important to understand community pharmacists practice in dealing with PPIs and to evaluate their despising pattern of these medications.

Method: A cross-sectional survey-based study that was carried out between September and December 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsps.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362272PMC
February 2019

Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance

Turk J Med Sci 2019 Feb 11;49(1):347-355. Epub 2019 Feb 11.

Background/aim: Ankaferd hemostat (ABS; Ankaferd blood stopper, İstanbul, Turkey) is a folkloric medicinal plant extract. The aim of this study was to determine the effect of Ankaferd hemostat (ABS) on the fate of Helicobacter pylori strains. The study also aims to determine alterations in the antimicrobial resistance of three different H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3906/sag-1807-206DOI Listing
February 2019

Helicobacter pylori and nutrition: a bidirectional communication.

Minerva Gastroenterol Dietol 2019 Feb 12. Epub 2019 Feb 12.

Unit of Dietetics and Clinical Nutrition, Città della Salute e della Scienza, Turin, Italy.

Helicobacter pylori (HP) is a gram negative flagellated pathogen acid-resistant bacterium; it belongs to the order Campylobacterales that is wide spread all over the world, infecting more than 50% of the world population. HP infection is etiologically associated with non-atrophic and atrophic gastritis, peptic ulcer and with 3 to 6-fold increased relative risk for developing gastric adenocarcinoma and mucosa-associated lymphoid tissue (MA LT) lymphoma. For this reason HP is recognized by the World Health Organization as a Class I human carcinogen. Read More

View Article

Download full-text PDF

Source
https://www.minervamedica.it/index2.php?show=R08Y9999N00A190
Publisher Site
http://dx.doi.org/10.23736/S1121-421X.19.02568-6DOI Listing
February 2019
1 Read

Rifabutin-Based Rescue Therapy for Eradication: A Long-Term Prospective Study in a Large Cohort of Difficult-to-Treat Patients.

J Clin Med 2019 Feb 6;8(2). Epub 2019 Feb 6.

Unit of Gastroenterology, Molinette Hospital, 10123 Turin, Italy.

The most commonly used regimens fail to eradicate () infection in 5⁻10% of patients. Those not cured with treatments based on amoxicillin, clarithromycin, nitroimidazoles, fluoroquinolones, bismuth or tetracycline have no other conventional options thereafter. In this prospective long-term monocentric study, patients who failed to eradicate following treatment with all conventional antibiotics were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm8020199DOI Listing
February 2019
1 Read

Helicobacter pylori infection promotes autophagy through Nrf2-mediated heme oxygenase upregulation in human gastric cancer cells.

Biochem Pharmacol 2019 Feb 4. Epub 2019 Feb 4.

Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul 08826, South Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Sciences and Technology, Seoul National University, Seoul 08826, South Korea; Cancer Research Institute, Seoul National University, Seoul 03080, South Korea. Electronic address:

It has been reported that Helicobacter pylori (H. pylori) infection is one of the primary causes of gastritis and peptic ulcer diseases. More than 50% of the world's population is supposed to be infected by this bacterium. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2019.02.003DOI Listing
February 2019
1 Read

Comorbid for gastroduodenal ulcers in the aspect of calcium imbalance and blockers of slow calcium channels in their treatment.

Authors:
L A Fomina

Ter Arkh 2018 Feb;90(2):28-34

Tver State Medical University, Ministry of Health of Russia, Tver, Russia.

Aim: Find out the calcium content of the blood reflecting its balance and functional status the calcium regulatory system when it is comorbid for gastroduodenal ulcers (GDU), developed on the background of chronic erosive gastritis (CEG), chronic erosive duodenitis (CED), arterial hypertension (AH) and osteo-articular pathology with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), and the impact of his changes on the activity ulzerogennogo process, the state of regional microcirculation and the functions of the stomach. To determine the pathogenetic justification for and effectiveness of blockers of slow calcium channels (BSCaC) in complex treatment.

Materials And Methods: Examined 132 patients with GDU. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26442/terarkh201890228-34DOI Listing
February 2018
1 Read

The Association of Gastritis and Peptic Ulcer With Polymorphisms in the Inflammatory-related Genes IL-4 and IL-10 in Iranian Population.

Iran J Pathol 2018 17;13(2):229-236. Epub 2018 Jul 17.

Dept. of Medical Genetics, Hormozgan University of Medical Science, Bandarabas, Iran.

Background & Objective: The current study aimed at assessing the relationship between gastritis and peptic ulcer susceptibility and inflammation-related gene polymorphisms in Iranian patients.Gastritis and peptic ulcer are common medical complications with serious outcomes on the quality of life. Inflammatory responses of gastric mucosa are associated with helicobacter pylori, but most infected patients remain asymptomatic. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339493PMC
July 2018
1 Read

Helicobacter pylori vacA, cagA and iceA genotypes in dyspeptic patients from southwestern region, Saudi Arabia: distribution and association with clinical outcomes and histopathological changes.

BMC Gastroenterol 2019 Jan 25;19(1):16. Epub 2019 Jan 25.

Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.

Background: The aim of this study was to identify the common H. pylori virulence genes among dyspeptic Southwestern Saudi patients and their association with clinical outcomes and histopathological findings to help practitioners and researchers in the region for better management of infections caused by such bacteria.

Methods: Four hundred two gastric biopsy specimens were analyzed using histopathological examination and real time-PCR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-019-0934-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346553PMC
January 2019
3 Reads

Efficacy and safety of Syferol-IHP for the treatment of peptic ulcer disease: a pilot, double-blind randomized trial.

Clin Exp Gastroenterol 2019 15;12:21-30. Epub 2019 Jan 15.

Biomedicine Research Group, Nnamdi Azikiwe University, Awka, Nigeria,

Background: To our knowledge, there is no prior randomized study on the utility of Syferol-IHP (blend of virgin coconut oil and oil) when coadministered with a triple therapy schedule.

Aim: This study determined the efficacy and safety of Syferol-IHP as adjunct to conventional triple therapy for the treatment of peptic ulcer disease (PUD).

Methods: A pilot double-blind randomized trial was conducted in patients with confirmed diagnosis (endoscopy-guided biopsy) of PUD. Read More

View Article

Download full-text PDF

Source
https://www.dovepress.com/efficacy-and-safety-of-syferol-ihp
Publisher Site
http://dx.doi.org/10.2147/CEG.S178179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338118PMC
January 2019
3 Reads

BST-104, a Water Extract of Lonicera japonica, Has a Gastroprotective Effect via Antioxidant and Anti-Inflammatory Activities.

J Med Food 2019 Feb 24;22(2):140-151. Epub 2019 Jan 24.

3 Department of Research, GREEN CROSS Wellbeing Co., Ltd., Seongnam, South Korea.

The gastroprotective effects of BST-104 (a water extract of Lonicera japonica) and the mechanisms involved were investigated in murine models of gastritis and peptic ulcer. The gastroprotective effects of BST-104 and its active components were evaluated in rat models of HCl/ethanol-induced gastritis and acetic acid-induced gastric ulcer. After orally administering BST-104, chlorogenic acid, rebamipide (positive control), or vehicle to each animal model, gastric lesion sizes, gastric mucus statuses, proinflammatory cytokine levels, and oxidative stress were measured. Read More

View Article

Download full-text PDF

Source
https://www.liebertpub.com/doi/10.1089/jmf.2018.4231
Publisher Site
http://dx.doi.org/10.1089/jmf.2018.4231DOI Listing
February 2019
3 Reads

Helicobacter pylori infection associated with an increased risk of colorectal adenomatous polyps in the Chinese population.

BMC Gastroenterol 2019 Jan 21;19(1):14. Epub 2019 Jan 21.

Statistical Genomics and Data Analysis Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.

Background: Gastric Helicobacter pylori (H. pylori) is linked with chronic gastritis, peptic ulcer disease, and gastric malignancy. This study aims to investigate the association of gastric H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-018-0918-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341657PMC
January 2019
1 Read

The lipoprotein HP1454 of Helicobacter pylori regulates T-cell response by shaping T-cell receptor signalling.

Cell Microbiol 2019 Jan 15:e13006. Epub 2019 Jan 15.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Helicobacter pylori (HP) is a Gram-negative bacterium that chronically infects the stomach of more than 50% of human population and represents a major cause of gastric cancer, gastric lymphoma, gastric autoimmunity, and peptic ulcer. It still remains to be elucidated, which HP virulence factors are important in the development of gastric disorders. Here, we analysed the role of the HP protein HP1454 in the host-pathogen interaction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cmi.13006DOI Listing
January 2019
6 Reads
4.915 Impact Factor

Helicobacter pylori Infection and Related Gastrointestinal Diseases in Southeast Asian Countries: An Expert Opinion Survey

Asian Pac J Cancer Prev 2018 Dec 25;19(12):3565-3569. Epub 2018 Dec 25.

Department of Internal Medicine, University of Medicine and Pharmacy at Hochiminh City, Hochiminh, Vietnam.

Background: Helicobacter pylori (H. pylori) infection is currently considered as an infectious disease irrespective of symptoms and stage of disease. This study aimed to survey the impact of H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31557/APJCP.2018.19.12.3565DOI Listing
December 2018
3 Reads

From Sidney to OLGA: an overview of atrophic gastritis.

Acta Biomed 2018 Dec 17;89(8-S):93-99. Epub 2018 Dec 17.

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Chronic gastritis is a long-lasting disease that can lead to a loss of appropriate gastric glands. Gastritis, as term, apply to an inflammation of the stomach, histologically proven, sometimes with structural mucosal changes. Worldwide Helicobacter pylori's infection play a pivotal role as the main etiological effector of chronic active gastritis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23750/abm.v89i8-S.7946DOI Listing
December 2018
2 Reads

Helicobacter pylori, transmission routes and recurrence of infection: state of the art.

Acta Biomed 2018 Dec 17;89(8-S):72-76. Epub 2018 Dec 17.

Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.

Helicobacter pylori (H. pylori) infection is one of the most common infection in humans, affecting more than half of the population. The prevalence of the infection varies widely in rural developing areas (more than 80%) compared to urban developed ones (less than 40%), as a consequence of different socioeconomic and hygienic conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23750/abm.v89i8-S.7947DOI Listing
December 2018
15 Reads

Relationship between Helicobacter pylori infection and GERD.

Acta Biomed 2018 Dec 17;89(8-S):40-43. Epub 2018 Dec 17.

Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.

Gastroesophageal reflux disease (GERD) is due to the chronic exposure of the esophageal mucosa to acid secretion from the stomach. Helicobacter pylori (H.p. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23750/abm.v89i8-S.7918DOI Listing
December 2018
1 Read

MicroRNA‑146a inhibits the inflammatory responses induced by interleukin‑17A during the infection of Helicobacter pylori.

Mol Med Rep 2019 Feb 5;19(2):1388-1395. Epub 2018 Dec 5.

Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China.

Helicobacter pylori (H. pylori) infection is the major cause of chronic active gastritis and peptic ulcer disease. Upregulation of IL‑17A is associated with H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/mmr.2018.9725DOI Listing
February 2019
1 Read

The value of oral contrast ultrasonography in the diagnosis of gastric cancer in elderly patients.

World J Surg Oncol 2018 Dec 7;16(1):233. Epub 2018 Dec 7.

Department of Ultrasonography, Chongming branch of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 25 South Gate Road, Cheng Qiao Town, Chongming District, Shanghai, 202150, China.

Background: This study aims to investigate the value of oral contrast ultrasonography (OCUS) in the diagnosis of gastric cancer in elderly patients.

Methods: OCUS data obtained from patients ≥ 60 years old were retrospectively analyzed and compared with gastroscopy results.

Results: Among the 12,716 subjects examined by OCUS, 5021 subjects were ≥ 60 years old, which accounted for 39. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12957-018-1527-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286526PMC
December 2018
2 Reads

Clinical features of Helicobacter pylori antibody-positive junior high school students in Nagano Prefecture, Japan.

Helicobacter 2018 Dec 4:e12559. Epub 2018 Dec 4.

Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan.

Background: Previously, we conducted an epidemiological study screening for Helicobacter pylori antibody positivity among Japanese junior high school students. In this study, we updated the epidemiological data and assessed the clinical features of H pylori antibody-positive junior high school students.

Materials And Methods: We assessed H pylori antibody-positive subjects who were identified between 2012 and 2015 at four junior high schools in Nagano Prefecture, Japan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/hel.12559DOI Listing
December 2018
2 Reads

Correlation between expression of MMP-9 and MMP-3 in Helicobacter pylori infected patients with different gastroduodenal diseases.

Arab J Gastroenterol 2018 Dec 30;19(4):148-154. Epub 2018 Nov 30.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address:

Background And Study Aims: Helicobacter pylori (H. pylori) has been implicated in the pathogenesis of most important gastro-duodenal diseases, such as gastritis, peptic ulcer disease (PUD) and gastric cancer. H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajg.2018.11.001DOI Listing
December 2018
1 Read

Recent trends in the prevalence of Helicobacter Pylori in symptomatic children: A 12-year retrospective study in a tertiary centre.

J Pediatr Surg 2018 Nov 6. Epub 2018 Nov 6.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China. Electronic address:

Objective: Helicobacter pylori infection is common among Asians. However, evidence in the recent years has demonstrated a decrease in the prevalence of H. pylori infection among children and adults worldwide. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpedsurg.2018.10.079DOI Listing
November 2018
3 Reads

Roles of Cholesteryl-α-Glucoside Transferase and Cholesteryl Glucosides in Maintenance of Helicobacter pylori Morphology, Cell Wall Integrity, and Resistance to Antibiotics.

MBio 2018 11 27;9(6). Epub 2018 Nov 27.

Pathogen Biology Laboratory, Department of Biotechnology and Bioinformatics, University of Hyderabad, Hyderabad, India

Infection of the human stomach caused by is very common, as the pathogen colonizes more than half of the world's population. It is associated with varied outcomes of infection, such as peptic ulcer disease, gastric ulcers, and mucosa-associated lymphoid tissue lymphoma, and is generally considered a risk factor for the development of gastric adenocarcinoma. Cholesteryl glucosides (CGs) constitute a vital component of the cell wall of and contribute to its pathogenicity and virulence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mBio.01523-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282200PMC
November 2018
2 Reads

Designing a novel ELISA method based on recombinant antigens to increase sensitivity and specificity of whole cell antigen detection.

Gastroenterol Hepatol Bed Bench 2018 ;11(4):333-342

Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Aim: In this research, we designed a direct Enzyme Linked Immunoassay method to detect antigens in stool specimens.

Background: infection as the worldwide problem is related to many gastrointestinal disorders such as gastritis, gastric cancer, non-ulcer disease, peptic ulcer disease and duodenal ulcer.

Methods: We produced and purified recombinant and antigens in and extracted their antibodies from a panel of positive sera specimens. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204246PMC
January 2018
19 Reads

Helicobacter pylori outer membrane vesicles involvement in the infection development and Helicobacter pylori-related diseases.

J Biomed Sci 2018 Nov 8;25(1):78. Epub 2018 Nov 8.

Laboratory of Gastroimmunology, Department of Immunology and Infectious Biology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237, Łódź, Poland.

Helicobacter pylori - (H. pylori) play a role in the pathogenesis of gastritis, gastric and duodenal ulcers as well as gastric cancer. A possible involvement of outer membrane vesicles (OMVs) produced by H. Read More

View Article

Download full-text PDF

Source
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929
Publisher Site
http://dx.doi.org/10.1186/s12929-018-0480-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225681PMC
November 2018
10 Reads

Is There a Reason for the Proton Pump Inhibitor? An Assessment of Prescribing for Residential Care Patients in British Columbia.

Can J Hosp Pharm 2018 Sep-Oct;71(5):295-301. Epub 2018 Oct 31.

, BSc(Pharm), PharmD, is with Lower Mainland Pharmacy Services, Surrey British Columbia, and the Therapeutics Initiative (The University of British Columbia), Vancouver, British Columbia.

Background: The use of proton pump inhibitors (PPIs) may cause significant harm to patients in the residential care setting, as these patients are often frail with multiple morbidities. The extent of non-evidence-based use of PPIs in residential care sites of the Fraser Health Authority in British Columbia is unknown.

Objective: To determine the proportion of non-evidence-based use of PPI therapy for residential care patients of the Fraser Health Authority. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209499PMC
October 2018
6 Reads

Pediatric Gastritis, Gastropathy, and Peptic Ulcer Disease.

Pediatr Rev 2018 Nov;39(11):542-549

Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Nicklaus Children's Hospital, Miami, FL.

View Article

Download full-text PDF

Source
http://pedsinreview.aappublications.org/lookup/doi/10.1542/p
Publisher Site
http://dx.doi.org/10.1542/pir.2017-0234DOI Listing
November 2018
4 Reads

ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats.

J Vet Intern Med 2018 Nov 31;32(6):1823-1840. Epub 2018 Oct 31.

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Texas A & M University, College Station, Texas.

The gastrointestinal (GI) mucosal barrier is continuously exposed to noxious toxins, reactive oxygen species, microbes, and drugs, leading to the development of inflammatory, erosive, and ultimately ulcerative lesions. This report offers a consensus opinion on the rational administration of GI protectants to dogs and cats, with an emphasis on proton pump inhibitors (PPIs), histamine type-2 receptor antagonists (H RAs), misoprostol, and sucralfate. These medications decrease gastric acidity or promote mucosal protective mechanisms, transforming the management of dyspepsia, peptic ulceration, and gastroesophageal reflux disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jvim.15337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271318PMC
November 2018
8 Reads

Efficacy of compound tablets combined with quadruple therapy for eradication and its correlation with pH value in the stomach: a study protocol of a randomised, assessor-blinded, single-centre study.

BMJ Open 2018 Oct 28;8(10):e023131. Epub 2018 Oct 28.

Department of Gastroenterology, Chongqing University Cancer Hospital &Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.

Introduction: (Hp) is an important pathogenic factor for chronic gastritis, peptic ulcer, gastric cancer, gastric mucosa-associated lymphoid tissue lymphoma and other diseases. In China, the Hp infection rate is high, but the eradication rate is decreasing. A large number of literatures have shown that the addition of can improve the Hp eradication rate and reduce the side effects of antibiotic treatments. Read More

View Article

Download full-text PDF

Source
http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02313
Publisher Site
http://dx.doi.org/10.1136/bmjopen-2018-023131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224731PMC
October 2018
8 Reads

Diagnosis of Infection in Children and Adolescents in Korea.

Pediatr Gastroenterol Hepatol Nutr 2018 Oct 10;21(4):219-233. Epub 2018 Oct 10.

Department of Pediatrics, Gyeongsang National Institute of Health Sciences, Gyeongsang National University College of Medicine, Jinju, Korea.

plays an important role in the pathogenesis of chronic gastritis, peptic ulcer disease, gastric cancer, and gastric mucosa-associated lymphoid tissue lymphoma. In Korea, the guidelines for the diagnosis and treatment of infection in adults were revised in 2013. The European Helicobacter and Microbiota Study Group and Consensus panel released the fifth edition of the Maastricht Consensus Report for the management of infection in 2015, and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the North American Society of Paediatric Gastroenterology, Hepatology and Nutrition released the updated joint guidelines for children and adolescents in 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5223/pghn.2018.21.4.219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182473PMC
October 2018
3 Reads

Gastrinoma of Cystic Duct: A Rare Association With Multiple Endocrine Neoplasia Type 1.

J Clin Med Res 2018 Nov 9;10(11):843-847. Epub 2018 Oct 9.

Department of Internal Medicine and Endocrine Unit, Medical School and Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Neuroendocrine tumors (NETs) of cystic duct are extremely rare, accounting for less than 2% of NET cases. The association of biliary tree NET and multiple endocrine neoplasm type 1 (MEN1) are even more rare. In this report, we described a case of a 65-year-old woman who was referred to our neuroendocrine outpatient clinic to investigate MEN1 after an incidental diagnosis of gastrinoma. Read More

View Article

Download full-text PDF

Source
http://www.jocmr.org/index.php/JOCMR/article/view/3541
Publisher Site
http://dx.doi.org/10.14740/jocmr3541wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188020PMC
November 2018
15 Reads

Association of and Polymorphisms in Chronic Gastritis and Peptic Ulcer.

Iran J Public Health 2018 Sep;47(9):1364-1370

Center for Research of Molecular Medicine, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran.

Background: are the main cause of chronic inflammation and peptic ulcer. We aimed to determine if 3954 and polymorphisms are associated with the risk of chronic gastritis and peptic ulcer in Iranian population.

Methods: In this case-control study, from 198 individuals enrolled by Mohammadi Hospital, Bandar Abbas, southern Iran from 2012 to 2014 and who showed the symptoms of chronic gastritis and 84 with peptic ulcer participated in the case group, two biopsies were taken from the body, antrum, or ulcer edge of each patient. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174059PMC
September 2018
4 Reads

Burden of gastrointestinal and liver diseases in India, 1990-2016.

Indian J Gastroenterol 2018 Sep 10;37(5):439-445. Epub 2018 Oct 10.

Gastrointestinal Epidemiology Research Center, Division of Gastroenterology, Hepatology and Department of Epidemiology, Johns Hopkins University, 600 N Wolfe St, Blalock 406, Baltimore, MD, 21287, USA.

There is no comprehensive report on the burden of gastrointestinal (GI) and liver diseases in India. In this study, we estimated the age-standardized prevalence, mortality, and disability adjusted life years (DALY) rates of GI and liver diseases in India from 1990 to 2016 using data from the Global Burden of Disease (GBD) Study, which systematically reviews literature and reports for international disease burden trends. Despite a decrease in the overall burden from GI infectious disorders since 1990, they still accounted for the majority of DALYs in 2016. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12664-018-0892-3
Publisher Site
http://dx.doi.org/10.1007/s12664-018-0892-3DOI Listing
September 2018
11 Reads

Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition?

Can J Infect Dis Med Microbiol 2018 10;2018:6237239. Epub 2018 Sep 10.

Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University, Rome, Italy.

() is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/6237239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151681PMC
September 2018
7 Reads

Prevalence and factors associated with H. pylori infection in Saudi patients with dyspepsia.

Electron Physician 2018 Sep 9;10(9):7279-7286. Epub 2018 Sep 9.

Associate Professor, Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.

Background: Helicobacter pylori (H. pylori) is a major cause of peptic ulcer disease (PUD) and chronic active gastritis that may progress to gastric cancer. Globally, it has been estimated that 50% or more of the world's population is infected by H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.19082/7279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140988PMC
September 2018
9 Reads

How far are we from vaccination against Helicobacter pylori infection?

Expert Rev Vaccines 2018 10 26;17(10):935-945. Epub 2018 Sep 26.

c Medical Faculty of Ljubljana , Institute of Microbiology and Immunology , Ljubljana , Slovenia.

Introduction: Helicobacter pylori infection results in chronic gastritis, peptic ulcer, or gastric cancer; therefore, eradication of this bacterium is essential. The strategy for developing effective vaccines against H. pylori entails immunization of mice with a combination of classical and recombinant H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14760584.2018.1526680DOI Listing
October 2018
1 Read

Helicobacter pylori infection and inflammatory bowel disease: a crosstalk between upper and lower digestive tract.

Cell Death Dis 2018 Sep 20;9(10):961. Epub 2018 Sep 20.

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, China.

Helicobacter pylori has coexisted with humans for approximately 60,000 years and greater than 50% of the global population is infected with H. pylori. H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41419-018-0982-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148320PMC
September 2018
1 Read

Astaxanthin Inhibits Mitochondrial Dysfunction and Interleukin-8 Expression in -Infected Gastric Epithelial Cells.

Nutrients 2018 Sep 18;10(9). Epub 2018 Sep 18.

Department of Food and Nutrition, Brain Korea 21 PLUS Project, College of Human Ecology, Yonsei University, Seoul 03722, Korea.

infection leads to gastric inflammation, peptic ulcer and gastric carcinoma. activates NADPH oxidase and increases reactive oxygen species (ROS), which induce NF-κB activation and IL-8 expression in gastric epithelial cells. Dysfunctional mitochondria trigger inflammatory cytokine production. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu10091320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164770PMC
September 2018
1 Read
3.150 Impact Factor

Helicobacter pylori and nonmalignant upper gastrointestinal diseases.

Helicobacter 2018 Sep;23 Suppl 1:e12522

Institute of Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania.

The review of the most important recent publications concerning the relation of Helicobacter pylori with peptic ulcer disease (PUD), noninvestigated and functional dyspepsia, and gastroesophageal reflux disease (GERD) is presented. H. pylori remains the main etiopathogenetic factor in complicated and uncomplicated PUD. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/hel.12522
Publisher Site
http://dx.doi.org/10.1111/hel.12522DOI Listing
September 2018
14 Reads

Helicobacter Pylori Infection and Lung Cancer: 
New Insights and Future Challenges.

Zhongguo Fei Ai Za Zhi 2018 Sep;21(9):658-662

Biomedical Research Laboratories, Medicine Faculty, Catholic University of Maule, Talca, Chile.

Helicobacter pylori (H. pylori) is the causative agent of chronic gastritis and peptic ulcer diseases and is an important risk factor for the development functional dyspepsia, peptic ulceration, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3779/j.issn.1009-3419.2018.09.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137001PMC
September 2018
11 Reads

Circulating long non-coding RNAs HULC and ZNFX1-AS1 are potential biomarkers in patients with gastric cancer.

Oncol Lett 2018 Oct 24;16(4):4689-4698. Epub 2018 Jul 24.

Department of Clinical Laboratory, Peking University People's Hospital, Beijing 100044, P.R. China.

Long non-coding RNAs (lncRNAs) have been demonstrated to be involved in different types of cancer, including gastric cancer. Although altered lncRNAs profiles have been observed in or around gastric cancer tissues, the diagnostic value of circulating lncRNAs in gastric cancer remains unclear. In the present study, a number of highly expressed lncRNAs, including uc001lsz, GACAT2, ABHD11-AS1, GACAT3, SUMP1P3, CHET1, TUG1, SNHG12, GAS5, PVT1, LINC00152, HOTAIR, CCAT1, H19, HULC and ZNFX1-AS1, were investigated as potential minimally invasive biomarkers for this tumor. Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/ol.2018.9199
Publisher Site
http://dx.doi.org/10.3892/ol.2018.9199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126347PMC
October 2018
6 Reads

[Application of Digestive Endoscopy in Diagnosis of Helicobacter Pylori Infection].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Aug;40(4):563-567

Department of Gastroenterology,the Second Hospital of Lanzhou University,Lanzhou 730000,China.

Helicobacter pylori (Hp),a proven pathogen of digestive disease,is closely associated with gastrointestinal diseases including peptic ulcer,chronic active gastritis,stomach cancer,and stomach-associated lymphoid tissue lymphoma. Thus,precise and timely diagnosis of Hp is of great significance. In addition to C or C breath test,rapid urease test,and other commonly used Hp diagnosis methods,some new endoscopic techniques such as magnifying endoscopy,narrow-band imaging,confocal laser endomicroscopy,Fuji intelligent chromoendoscopy,and I scanning have been used for the direct observation of the fine-structure of stomach with Hp infection or for the identification of living Hp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3881/j.issn.1000-503X.10192DOI Listing
August 2018
1 Read

4-Hydroxynonenal in Redox Homeostasis of Gastrointestinal Mucosa: Implications for the Stomach in Health and Diseases.

Antioxidants (Basel) 2018 Sep 3;7(9). Epub 2018 Sep 3.

Laboratory for Oxidative Stress (LabOS), Institute "Rudjer Boskovic", HR-10000 Zagreb, Croatia.

Maintenance of integrity and function of the gastric mucosa (GM) requires a high regeneration rate of epithelial cells during the whole life span. The health of the gastric epithelium highly depends on redox homeostasis, antioxidant defense, and activity of detoxifying systems within the cells, as well as robustness of blood supply. Bioactive products of lipid peroxidation, in particular, second messengers of free radicals, the bellwether of which is 4-hydroxynonenal (HNE), are important mediators in physiological adaptive reactions and signaling, but they are also thought to be implicated in the pathogenesis of numerous gastric diseases. Read More

View Article

Download full-text PDF

Source
http://www.mdpi.com/2076-3921/7/9/118
Publisher Site
http://dx.doi.org/10.3390/antiox7090118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162398PMC
September 2018
15 Reads

The Probiotic for Alleviation of -Associated Gastric Pathology in East Africa.

Front Microbiol 2018 14;9:1873. Epub 2018 Aug 14.

Department of Molecular Cell Biology, VU University Amsterdam, Amsterdam, Netherlands.

The probiotic GG (LGG) can play a role in establishing a harmless relationship with and reduce gastric pathology in East African populations. has the ability to inhabit the surface of the mucous layer of the human stomach and duodenum. In the developing world, an estimated 51% of the population is carrier of , while in some Western countries these numbers dropped below 20%, which is probably associated with improved sanitation and smaller family sizes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2018.01873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102400PMC
August 2018
3 Reads

Effect of sequential therapy on treatment of Helicobacter pylori infection in children.

Rev Gastroenterol Peru 2018 Apr-Jun;38(2):128-130

Alimenatry Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Helicobacter pylori infection which plays a major role in the etiology of chronic gastritis and duodenal ulcers in children and adults is one of the commonest chronic infection worldwide. Cure of the infection leads to healing of gastric inflammation and prevention of peptic ulcer.

Objective: The aim of this study was to evaluate the efficacy of the sequential therapy for treatment of Helicobacter pylori infection. Read More

View Article

Download full-text PDF

Source
December 2018
3 Reads

Artepillin C, drupanin, aromadendrin-4'-O-methyl-ether and kaempferide from Brazilian green propolis promote gastroprotective action by diversified mode of action.

J Ethnopharmacol 2018 Nov 11;226:82-89. Epub 2018 Aug 11.

Programa de Pós Graduação em Ciências Farmacêuticas, Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Universidade do Vale do Itajai (UNIVALI) - Campus Itajaí, Rua Uruguai, 458, Centro CEP: 88302-901, Santa Catarina, Brazil. Electronic address:

Ethopharmacological Relevance: The propolis is extensively used in folk medicine in natura or to prepare pharmaceutical formulations since ancient time to improve health or prevent diseases, among them gastrointestinal disorders. Aiming to contribute in the scientific validation about the popular use of Brazilian Green propolis (BGP) against gastritis and gastric ulcer, this work evaluated the antiulcer potential of isolated compounds from BGP, three prenylated p-coumaric acid derivatives and two flavonoids, respectively named: 3,5 diprenyl-4-hydroxycinnamic acid (artepillin C) (1), 3-prenyl-4-dihydroxycinnamoiloxy cinnamic acid (baccharin) (2), 3-prenyl-4-hydroxycinnamic acid (drupanin) (3), aromadendrin-4'-O-methyl-ether (4) and kaempferide (5).

Material And Methods: The compounds were characterized by nuclear magnetic resonance and mass spectrometry. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2018.08.006DOI Listing
November 2018
20 Reads

Characterization of clarithromycin heteroresistance among Helicobacter pylori strains isolated from the antrum and corpus of the stomach.

Folia Microbiol (Praha) 2019 Mar 10;64(2):143-151. Epub 2018 Aug 10.

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mixed infections and heteroresistance of Helicobacter pylori contribute to decreased efficacy of treatments. This study aimed to investigate frequency of clarithromycin heteroresistance and its link with mixed infections, medication history, and disease severity. A total of 40 pairs of H. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12223-018-0637-9DOI Listing
March 2019
2 Reads

urease for diagnosis of infection: A mini review.

J Adv Res 2018 Sep 31;13:51-57. Epub 2018 Jan 31.

Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Institute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.

The stomach contents contain of both acid and proteolytic enzymes. How the stomach digests food without damaging itself remained a topic of investigation for decades. One candidate was gastric urease, which neutralized acid by producing ammonia from urea diffusing from the blood and potentially could protect the stomach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jare.2018.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077137PMC
September 2018
1 Read

HELICOBACTER PYLORI INFECTION AND IMMUNE PROFILE OF PATIENTS WITH DIFFERENT GASTRODUODENAL DISEASES.

Arq Gastroenterol 2018 Apr-Jun;55(2):122-127

Universidade Federal do Pará, Laboratório de Patologia Clínica de Doenças Tropicais, Belém, PA, Brasil.

Background: The association between infection with Helicobacter pylori and different gastroduodenal diseases is related to bacterial, host and environmental factors. Studies have demonstrated an association between the genetic diversity of H. pylori, especially in the vacA and cagA genes, and the development of digestive diseases such as peptic ulcer and gastric cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/S0004-2803.201800000-21DOI Listing
September 2018
12 Reads

Systemic diseases and other painful conditions in patients with temporomandibular disorders and migraine.

Braz Oral Res 2018 Jul 23;32:e77. Epub 2018 Jul 23.

Universidade Estadual Paulista - UNESP, Araraquara Dental School, Department of Dental Materials and Prosthodontics, Araraquara, SP, Brazil.

Temporomandibular disorders (TMD) are a highly prevalent, painful musculoskeletal condition affecting the masticatory system, and are frequently associated with migraines (M) and other diseases. This study aimed to investigate the association between painful TMD and M with other painful conditions and systemic diseases, such as cervicalgia, body pain (BP), ear-nose-throat disorders, musculoskeletal disorders, diabetes, cardiopulmonary diseases and gastritis/peptic ulcer.

Methods: This was a cross-sectional study conducted in a sample of 352 individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/1807-3107BOR-2018.vol32.0077DOI Listing
July 2018
4 Reads