8,473 results match your criteria Gastritis and Peptic Ulcer Disease


Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosis.

PLoS Pathog 2022 Jun 29;18(6):e1010628. Epub 2022 Jun 29.

Department of Surgery, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.

Helicobacter pylori (H. pylori) is a common gastric pathogen that infects approximately half of the world's population. Infection with H. Read More

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The relationship between helicobacter pylori infection and nodular antral gastritis in pediatric patients.

J Natl Med Assoc 2022 Jun 25. Epub 2022 Jun 25.

Pediatric Infectious Diseases, Selçuk University Medical School, Konya, Turkey.

Background: Helicobacter pylori (H. pylori) is a spiral-shaped gram-negative bacterium that colonizes the gastric mucosa. It is a common infectious agent in children. Read More

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[A comparative analysis of the distribution of the high-risk population of upper gastrointestinal cancer and endoscopic screening compliance in two urban areas and two rural areas in China].

Zhonghua Zhong Liu Za Zhi 2022 Jun;44(6):531-539

Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To analyze and compare the distribution of the high-risk population of upper gastrointestinal (UGI) cancer and the factors influencing the compliance rate of endoscopic screening in urban China and rural China. From 2015 to 2017, an epidemiological survey was conducted on residents aged 40-69 in two rural areas (Luoshan county of Henan province, Sheyang county of Jiangsu province) and two urban areas (Changsha city of Hunan province, Harbin city of Heilongjiang province). As a result, high-risk individuals were recommended for endoscopic screening. Read More

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Antibiotic Resistance of in Children with Gastritis and Peptic Ulcers in Mekong Delta, Vietnam.

Healthcare (Basel) 2022 Jun 17;10(6). Epub 2022 Jun 17.

Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, Vietnam.

Background: () infection causes gastritis, duodenal and gastric ulcers, and gastric cancer. eradication efficacy is low worldwide, and antibiotic resistance is the leading cause of therapy failure; therefore, this study was performed to determine the characteristics of antibiotic resistance of in children with gastritis, duodenal and gastric ulcer.

Methods: A cross-sectional study was conducted on 237 pediatric patients diagnosed with gastroduodenal inflammation and ulcer at two hospitals in Vietnam from March 2019 to April 2022. Read More

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Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori-related diseases.

Fundam Clin Pharmacol 2022 Jun 18. Epub 2022 Jun 18.

Clinical Microbiology Research Centre, Ilam University of Medical Sciences, Ilam, Iran.

Helicobacter pylori (H. pylori) is a microaerophilic gastric pathogen and a major contributor to chronic atrophic gastritis, peptic ulcer, and gastric malignancies. The increasing prevalence of H. Read More

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Randomized Clinical Trial on the Efficacy of Triple Therapy Versus Sequential Therapy in Helicobacter pylori Eradication.

Cureus 2022 May 10;14(5):e24897. Epub 2022 May 10.

General Surgery, Maroof International Hospital, Islamabad, PAK.

Introduction: () colonization is prevalent all over the world, and it is associated with low socioeconomic status, poor hygiene, and overcrowding. Its eradication is important since it is an etiologic agent for gastritis, peptic ulcer, gastric carcinoma, and mucosa-associated lymphoid tissue lymphoma. Different regimens are available for the eradication of and include triple therapy and sequential therapy. Read More

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Animal Models and Infection.

J Clin Med 2022 May 31;11(11). Epub 2022 May 31.

Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Oita, Japan.

colonize the gastric mucosa of at least half of the world's population. Persistent infection is associated with the development of gastritis, peptic ulcer disease, and an increased risk of gastric cancer and gastric-mucosa-associated lymphoid tissue (MALT) lymphoma. In vivo studies using several animal models have provided crucial evidence for understanding the pathophysiology of -associated complications. Read More

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Analysis of Adverse Reactions of Aspirin in Prophylaxis Medication Based on FAERS Database.

Comput Math Methods Med 2022 26;2022:7882277. Epub 2022 May 26.

Department of Neurology, Jinnan Nanjiao Hospital, Jinan City 250000, Shandong Province, China.

Objective: As the most commonly used drug in the world, aspirin has shown benefits for myocardial infarction, stroke, and vascular death in many secondary prevention trials and their meta-analysis. The purpose of this study was to evaluate the association between aspirin and its adverse reactions as a preventive drug using the FDA adverse event reporting system (FAERS).

Methods: The FAERS database was queried for the adverse drug events (ADE) reported from the first quarter of 2004 to the second quarter of 2021. Read More

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Use of Proton Pump Inhibitors With Dexamethasone in Patients With COVID-19 Pneumonia: Contributions to Long-Term Polypharmacy.

Cureus 2022 May 2;14(5):e24661. Epub 2022 May 2.

Gastroenterology, NewYork-Presbyterian Brooklyn Methodist Hospital, Brooklyn, USA.

Introduction  Proton pump inhibitors have been used in conjunction with dexamethasone to treat patients with COVID-19. This is given prophylactically to anticipate possible complications while on steroids, including abdominal pain, gastric ulcers, or gastrointestinal bleeding. Proton pump inhibitors have complications, including infection, pneumonia, osteoporosis, and vitamin deficiency. Read More

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Upper gastrointestinal system bleedings in COVID-19 patients: Risk factors and management/a retrospective cohort study.

Ulus Travma Acil Cerrahi Derg 2022 Jun;28(6):762-768

Department of General Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey.

Background: Upper gastrointestinal system bleeding (UGIB) that occurs with the effect of coagulopathy due to COVID-19 disease itself and drugs such as LMWH and steroids used in the treatment negatively affects the outcomes. In this study, we aimed to examine the frequency of gastrointestinal system bleeding in COVID-19 patients, risk factors, effect on outcomes, and management.

Methods: Institutional center (a third-level pandemic center) database was searched for patients hospitalized for COVID-19 between March 11, 2020, and December 17, 2020, retrospectively. Read More

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Targeting the Essential Transcription Factor HP1043 of : A Drug Repositioning Study.

Front Mol Biosci 2022 11;9:887564. Epub 2022 May 11.

Istituto di Tecnologie Biomediche-Consiglio Nazionale Delle Ricerche (ITB-CNR), Segrate (Mi), Italy.

Antibiotic-resistant bacterial pathogens are a very challenging problem nowadays. is one of the most widespread and successful human pathogens since it colonizes half of the world population causing chronic and atrophic gastritis, peptic ulcer, mucosa-associated lymphoid tissue-lymphoma, and even gastric adenocarcinoma. Moreover, it displays resistance to numerous antibiotics. Read More

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GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on .

J Enzyme Inhib Med Chem 2022 Dec;37(1):1610-1619

Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

can cause chronic gastritis, peptic ulcer, and gastric carcinoma. This study compares chemical composition and activity of mandarin leaves and marjoram herb essential oils, and their combined oil. GC/MS analysis of mandarin oil revealed six compounds (100% identified), mainly methyl--methyl anthranilate (89. Read More

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December 2022

Preoperative esophagogastroduodenoscopy findings and effects on laparoscopic Roux-en-Y gastric bypass in area with high prevalence of infection: multi-center experience in Iran.

Gastroenterol Hepatol Bed Bench 2022 ;15(1):53-58

Golestan Research Center of Gastroenterology and Hepatology (GRCGH), Golestan University of Medical Sciences, Gorgan, Iran.

Aim: The current study aimed to evaluate EGD findings effects on laparoscopic Roux-en-Y gastric bypass (RYGB) plan and time in areas with a high prevalence of infection.

Background: Esophagogastroduodenoscopy (EGD) and testing are routine parts of preoperative assessment of bariatric surgery at many centers.

Methods: This was a crosssectional study of all patients underwent EGD and histopathological examination before laparoscopic RYGB in three gastroenterology centers in Iran between January 2018 and December 2020. Read More

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January 2022

The development of a colorimetric biosensing assay for the detection of Helicobacter pylori in feces.

Anal Biochem 2022 08 18;651:114737. Epub 2022 May 18.

West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, Sichuan, PR China; West China-PUMC C.C. Chen Institute of Health, Sichuan University, Chengdu, 610041, Sichuan, PR China. Electronic address:

As Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric diseases such as chronic gastritis, peptic ulcer, and gastric cancer, early detection of H. pylori is an urgent need. Read More

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Mapping microbiome-redox spectrum and evaluating Microbial-Redox Index in chronic gastritis.

Sci Rep 2022 May 19;12(1):8450. Epub 2022 May 19.

Center of Excellence for Clinical Microbiome Research, All India Institute of Medical Sciences, Bhubaneswar, 751019, India.

Peptic ulcer disease (PUD) and chronic gastritis are prevalent in developing countries. The role of oxidative stress in the pathogenesis of gastrointestinal mucosal disorders is well recognized. In PUD, the gastric mucosa and its associated microbiome are subject to diet and stress-induced oxidative perturbations. Read More

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Transjugular intrahepatic portosystemic shunt with or without gastro-oesophageal variceal embolisation for the prevention of variceal rebleeding: a randomised controlled trial.

Lancet Gastroenterol Hepatol 2022 May 16. Epub 2022 May 16.

Department of Liver Diseases and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China; Department of Liver Diseases and Interventional Radiology, Digestive Diseases Hospital, Xi'an International Medical Center Hospital, Northwest University, Xi'an, China. Electronic address:

Background: The role of variceal embolisation at the time of transjugular intrahepatic portosystemic shunt (TIPS) creation for the prevention of gastro-oesophageal variceal rebleeding remains controversial. This study aimed to evaluate whether adding variceal embolisation to TIPS placement could reduce the incidence of rebleeding after TIPS in patients with cirrhosis.

Methods: We did an open-label, randomised controlled trial at one university hospital in China. Read More

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Correction to: Role of Th22 cells in Helicobacter pylori‑related gastritis and peptic ulcer diseases.

Mol Biol Rep 2022 May 8. Epub 2022 May 8.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.

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Evaluating the MicroRNA Expression of IL-35 and IL-37 in Helicobacter Pylori-infected Patients with Gastritis and Gastric Ulcer.

Iran J Allergy Asthma Immunol 2022 Feb 6;21(1):20-26. Epub 2022 Feb 6.

Department of Immunology, Cellular and Molecular Research Center, Basic Health Sciences Institute, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Interleukin (IL)-35 and IL-37 are two anti-inflammatory cytokines. IL-35 inhibits the development of T-effector cells such as Th1, and Th17; while increasing regulatory T cells (Tregs). IL-37 causes the suppression of inflammatory cytokines. Read More

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February 2022

Endoscopic Findings in Patients With Upper Gastrointestinal Bleeding in Ogun State, Nigeria.

Cureus 2022 Mar 30;14(3):e23637. Epub 2022 Mar 30.

Medicine, Babcock University Teaching Hospital, Ilishan-Remo, NGA.

Introduction Although the global incidence of upper gastrointestinal bleeding (UGIB) appears to have reduced substantially in the past few decades, acute UGIB still carries significant morbidity and mortality worldwide. There are currently no published data on UGIB in Ogun State, Nigeria. This study examined the endoscopic findings in patients with UGIB in Ogun State. Read More

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Inflammatory map of the gastroduodenal mucosa in patients with upper gastrointestinal symptoms. The role of H. pylori infection.

Rev Gastroenterol Mex (Engl Ed) 2022 May 1. Epub 2022 May 1.

Universidad de Granada, Granada, Spain.

Introduction And Aim: The gastric mucosa has been studied since the pre-Helicobacter pylori (H. pylori) era, but the complete descriptions of the stomach and duodenum have been anecdotal, and those of the distal duodenum, exceptional. Our aim was to evaluate the different epidemiologic characteristics and the gastroduodenal inflammatory status in patients with upper gastrointestinal symptoms. Read More

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infection in non-ulcer dyspepsia: A cross-sectional study.

Med J Armed Forces India 2022 Apr 27;78(2):180-184. Epub 2021 Feb 27.

Graded Specialist (Medicine), Base Hospital Barrackpore, West Bengal, India.

Background: infection has been known to be associated with dyspepsia for more than two decades; however, studies on this topic in India are limited. This study was carried out to estimate the infection rates in non-ulcer dyspepsia.

Methods: infection rates detected by rapid urease test (RUT) positivity were analyzed in 235 patients presenting to a tertiary care center with dyspepsia having no evidence of peptic ulcer disease on esophagogastroduodenoscopy. Read More

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Eosinophilic Duodenal Ulcer Exacerbation after Helicobacter pylori Eradication in a 14-Year-Old Boy.

Tohoku J Exp Med 2022 Jun 21;257(2):153-156. Epub 2022 Apr 21.

Department of Pediatrics, Dokkyo Medical University.

Eosinophilic gastrointestinal disorders (EGIDs) cause various gastrointestinal symptoms due to infiltration of eosinophils into the gastrointestinal tract. Helicobacter pylori (H. pylori) is a microorganism that is associated with various diseases such as autoimmune diseases. Read More

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Clinical Presentation of Cases with Upper Gastro - Intestinal Bleeding.

J Assoc Physicians India 2022 Apr;70(4):11-12

Care Hospitals, Nampally, Hyderabad.

Acute upper gastrointestinal bleeding (UGIB) is a common emergency and can be a serious condition that requires hospitalization, rapid evaluation and management. The usual presentation is hematemesis (vomiting of blood or coffee ground-like material) and/or melena (black, tarry stools) 1. UGIB occurs more commonly in men and older subjects. Read More

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Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach.

Endosc Int Open 2022 Apr 14;10(4):E441-E447. Epub 2022 Apr 14.

Osaka International Cancer Institute, Department of Gastrointestinal Oncology, Osaka, Japan.

 The light blue crest observed in narrow band imaging endoscopy has high diagnostic accuracy for diagnosis of gastric intestinal metaplasia (GIM). The objective of this prospective study was to evaluate the diagnostic accuracy of magnifying i-scan optical enhancement (OE) imaging for diagnosing the LBC sign in patients with different levels of risk for gastric cancer in a Mexican clinical practice.  Patients with a history of peptic ulcer and symptoms of dyspepsia or gastroesophageal reflux disease were enrolled. Read More

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Stop of proton-pump inhibitor treatment in patients with liver cirrhosis (STOPPIT): study protocol for a prospective, multicentre, controlled, randomized, double-blind trial.

Trials 2022 Apr 12;23(1):302. Epub 2022 Apr 12.

I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: Proton-pump inhibitors (PPI) are liberally prescribed in patients with liver cirrhosis. Observational studies link PPI therapy in cirrhotic patients with an increased risk for infectious complications, hepatic encephalopathy and an increased risk for hospitalization and mortality. However, patients with liver cirrhosis are also considered to be at risk for peptic ulcer bleeding. Read More

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Gastric Outlet Obstruction Caused by a Duodenal Clot.

Cureus 2022 Mar 3;14(3):e22814. Epub 2022 Mar 3.

Gastroenterology, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.

Gastric outlet obstruction (GOO) is a mechanical obstruction usually located in the gastric pylorus or duodenum. After the introduction of proton pump inhibitors (PPIs) in the late 1980s, most cases of gastric outlet obstruction are now caused by malignancy and peptic ulcer disease rarely leads to obstruction. We present a case of GOO caused by a large clot in the pylorus, preventing visualization of the source of bleeding. Read More

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Second line therapy for Helicobacter pylori eradication: state of art.

Mini Rev Med Chem 2022 Mar 25. Epub 2022 Mar 25.

Section of Gastroenterology, Department of Emergency and Organ Transplantation, University \'Aldo Moro\' of Bari, 70124 Bari, Italy.

Helicobacter pylori (H. pylori) is a Gram negative spiraliform bacterium who colonizes the human stomach. It is the most common cause of chronic gastritis, peptic ulcer, and gastric carcinoma. Read More

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Bowel Health in U.S. Shift Workers: Insights from a Cross-Sectional Study (NHANES).

Int J Environ Res Public Health 2022 03 11;19(6). Epub 2022 Mar 11.

Center for Complementary Medicine, Department of Internal Medicine II, Freiburg University Hospital, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

Working outside of regular daytime hours is increasingly common in current societies and poses a substantial challenge to an individual's biological rhythm. Disruptions of the gastrointestinal tract's circadian rhythm and poor dietary choices subsequent to shiftwork may predispose the shift workforce to an increased risk of gastrointestinal disorders, including constipation, peptic ulcer disease, and erosive gastritis. We investigated bowel health in a US population of shift workers, using data from the National Health and Nutrition Examination Survey, and compared bowel movement (BM) frequency and defecation patterns between 2007 day workers and 458 shift workers (representing 55,305,037 US workers). Read More

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Anemia in nursing homes, proton pump inhibitors and prescribing cascade of antianemic drugs.

Eur Geriatr Med 2022 06 23;13(3):553-558. Epub 2022 Mar 23.

Laboratory of Clinical Pharmacology and Appropriateness of Drug Prescription, Department of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri, 2, 20156, Milan, Italy.

Purpose: Some medications can cause anemia through their effect on gastrointestinal function, such as proton pump inhibitors and H2-antagonists, and on the risk of bleeding, such as anticoagulants and antiplatelet agents. The main aim of this study is to evaluate how anemia is related with the most commonly used drugs in a large sample of NH residents.

Methods: This retrospective cross-sectional multicenter study was conducted in a sample of Italian long-term care NHs distributed throughout the country. Read More

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Extraction of antibacterial peptides against from bovine milk casein.

Arch Med Sci 2022 24;18(2):376-381. Epub 2021 Mar 24.

School of Health Sciences, Macao Polytechnic Institute, Macao, China.

Introduction: More than half of the world's population is infected with , which may cause gastritis, peptic ulcer and even gastric cancer. The World Health Organization (WHO) has announced that infection is a class I carcinogen and hence eradication of it is highly important. Bovine milk contains caseins, which can be digested by various enzymes in the human stomach to produce antibacterial peptides. Read More

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