8,136 results match your criteria Gastritis and Peptic Ulcer Disease


Prevalence and Risk Factors of Infection among Children Aged 1 to 15 Years at Holy Innocents Children's Hospital, Mbarara, South Western Uganda.

J Trop Med 2019 7;2019:9303072. Epub 2019 Mar 7.

Mbarara University of Science and Technology, Faculty of Medicine, Department of Medical Laboratory Sciences, P.O. Box 1410, Mbarara, Uganda.

Background: infection affects more than half of the world's population. The infection is generally acquired during childhood but can remain asymptomatic, with long-term clinical sequelae including gastritis, peptic ulcer disease, and stomach cancer.

Methods: The study was approved by Institutional Review Committee of Mbarara University of Science and Technology. Read More

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http://dx.doi.org/10.1155/2019/9303072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431523PMC
March 2019
1 Read

Ethnic Disparities in Gastric Cancer Presentation and Screening Practice in the United States: Analysis of 1997-2010 Surveillance, Epidemiology, and End Results-Medicare Data.

Cancer Epidemiol Biomarkers Prev 2019 Apr 26;28(4):659-665. Epub 2019 Mar 26.

Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.

Background: Chronic infection with () is the strongest risk factor for distal gastric cancer. Although gastric cancer incidence has decreased, variation by race and ethnicity is observed. This study describes gastric cancer presentation and screening services among Medicare patients by race/ethnicity, place of birth, and history of gastric cancer-related conditions. Read More

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0471DOI Listing
April 2019
1 Read

Helicobacter pylori: molecular basis for colonization and survival in gastric environment and resistance to antibiotics. A short review.

Infect Dis (Lond) 2019 Mar 25:1-10. Epub 2019 Mar 25.

b Unit of Gastroenterology , Molinette-SGAS Hospital , Turin , Italy.

Helicobacter pylori is a human-specific pathogen with a strict tropism for the gastric mucosa. This bacterium infects around half of the world population and is the main responsible for gastritis, peptic ulcer and, in some cases, for the pathogenesis of gastric cancer. Nevertheless, disease development in infected subjects depends not only on the bacterium, but also on the host genetic predisposition and on environmental factors. Read More

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http://dx.doi.org/10.1080/23744235.2019.1588472DOI Listing
March 2019
3 Reads

PREVALENCE OF HELICOBACTER PYLORI INFECTION IN DYSPEPTIC PATIENTS AND ITS ASSOCIATION WITH CLINICAL RISK FACTORS FOR DEVELOPING GASTRIC ADENOCARCINOMA.

Arq Gastroenterol 2019 Mar 18. Epub 2019 Mar 18.

Universidade Federal de Goiás, Faculdade de Farmácia, Goiânia, GO, Brasil.

Background: In Brazil, particularly in the underdeveloped localities, the prevalence of Helicobacter pylori (H. pylori) infections can range up to 90%. These rates are higher in older individuals and vary by country region. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/S0004-2803.201900000-03DOI Listing
March 2019
7 Reads

Impact of Helicobacter pylori Infection on Gastric Variceal Bleeding among Patients with Liver Cirrhosis.

Gastroenterol Res Pract 2019 10;2019:6529420. Epub 2019 Feb 10.

Tropical Medicine Department, Tanta University, Egypt.

Background And Aims: Currently, it is well known that Helicobacter pylori- (-) related peptic ulcer is one of the main causes of nonvariceal bleeding in cirrhotic patients. However, there is a lack of data to identify the exact effect of infection on variceal bleeding. This study was conducted to identify the impact of infection on gastric variceal bleeding in cirrhotic patients. Read More

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http://dx.doi.org/10.1155/2019/6529420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387698PMC
February 2019
1 Read
1.502 Impact Factor

Application of PCR and Microscopy to Detect in Gastric Biopsy Specimen among Acid Peptic Disorders at Tertiary Care Centre in Eastern Nepal.

Can J Infect Dis Med Microbiol 2019 5;2019:3695307. Epub 2019 Feb 5.

Department of Microbiology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.

Background: infection is most prevalent in developing countries. It is an etiological agent of peptic ulcer, gastric adenocarcinoma, and mucosal-associated lymphoid tissue (MALT) lymphoma. Despite the development of different assays to confirm infection, the diagnosis of infection is challenged by precision of the applied assay. Read More

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http://dx.doi.org/10.1155/2019/3695307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379864PMC
February 2019
1 Read

Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins.

Mucosal Immunol 2019 05 7;12(3):784-794. Epub 2019 Mar 7.

Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, 41390, Sweden.

Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. H. suis colonizes the gastric mucosa of 60-95% of pigs at slaughter age, and is associated with chronic gastritis, decreased weight gain, and ulcers. Read More

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http://dx.doi.org/10.1038/s41385-019-0154-4DOI Listing
May 2019
1 Read

GastroPanel® Biomarker Assay: The Most Comprehensive Test for Infection and Its Clinical Sequelae. A Critical Review.

Anticancer Res 2019 Mar;39(3):1091-1104

Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai, P.R. China.

Background/aim: Several clinical conditions seriously hamper the diagnostic accuracy of the commonly used tests for Helicobacter pylori (Hp), C-urea breath test (UBT) and stool antigen test (SAT). The present communication is a critical review of the potential limitations of UBT and SAT, and describes the approach on how these can be avoided. Drawbacks of the Hp tests: False-negative results are most often due to low bacterial load in the stomach due to: i) use of proton pump inhibitor medication; ii) use of antibiotics; iii) presence of atrophic gastritis and hypoacid stomach; iv); bleeding peptic ulcer; v) gastric cancer (GC) and vi) mucosal-associated lymphatic tissue lymphoma. Read More

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http://dx.doi.org/10.21873/anticanres.13218DOI Listing
March 2019
2 Reads

Byrsonima intermedia A. Juss partitions promote gastroprotection against peptic ulcers and improve healing through antioxidant and anti-inflammatory activities.

Biomed Pharmacother 2019 Mar 12;111:1112-1123. Epub 2019 Jan 12.

Departamento de Fisiologia, UNESP - Universidade Estadual Paulista, Instituto de Biociências, CEP 18618-970, Botucatu, São Paulo, Brazil. Electronic address:

Byrsonima intermedia is a species of bush popularly used to treat gastrointestinal disorders, such as gastric ulcers, gastritis, and diarrhea. Previous studies have revealed that the methanolic crude extract of B. intermedia leaves has gastroprotective and healing properties. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.12.132DOI Listing
March 2019
3 Reads

Insights into the design of inhibitors of the urease enzyme - a major target for the treatment of Helicobacter pylori infections.

Curr Med Chem 2019 Mar 1. Epub 2019 Mar 1.

Faculty of Pharmaceutical Sciences, University of Campinas - UNICAMP, Rua Cândido Portinari 200, 13083-871 Campinas-SP. Brazil.

Expressed by a variety of plants, fungi and bacteria, the urease enzyme is directly associated with the virulence factor of many bacteria, including Helicobacter pylori, a gram-negative bacterium related with several gastrointestinal diseases and responsible for one of the most frequent bacterial infections throughout the world. The Helicobacter pylori urease (HPU) is a nickel-dependent metalloenzyme expressed in response to the environmental stress caused by the acidic pH of the stomach. The enzyme promotes the increase of gastric pH through acid neutralization by the products of urea hydrolysis, then critically contributing to the colonization and pathogenesis of the microorganism. Read More

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http://dx.doi.org/10.2174/0929867326666190301143549DOI Listing
March 2019
2 Reads

The eradication of Helicobacter pylori to prevent gastric cancer: a critical appraisal.

Expert Rev Gastroenterol Hepatol 2019 Jan 13;13(1):17-24. Epub 2018 Nov 13.

f Department of Medicine , Michael E. DeBakey VA Medical Center, and Baylor College of Medicine , Houston , TX , USA.

Introduction: Gastric cancer is one of the top causes of cancer-related death worldwide. How to eliminate gastric cancer is an urgent public-health issue. Areas covered: In this review, we present up-to-date results of studies on gastric cancer prevention through the eradication of Helicobacter pylori and discuss strategies and obstacles for the implementation of population-wide screening and treatment of this pathogen to prevent gastric cancer. Read More

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http://dx.doi.org/10.1080/17474124.2019.1542299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391731PMC
January 2019
2 Reads

Attitude and knowledge of Saudi community pharmacists towards use of proton pump inhibitors.

Saudi Pharm J 2019 Feb 7;27(2):225-228. Epub 2018 Nov 7.

Department of Clinical Pharmacy, King Saud University, Saudi Arabia.

Introduction: Proton pump inhibitors (PPIs) effectively suppress acid secretion and play an important role in peptic ulcer disease and gastroesophageal reflux disease There is a real concern about the overutilization of PPIs, which will lead to significant high cost and undesirable outcomes Despite that most of PPIs are classified as prescribed medications, yet most of their users take them without prescription in Saudi Arabia. Therefore, it was important to understand community pharmacists practice in dealing with PPIs and to evaluate their despising pattern of these medications.

Method: A cross-sectional survey-based study that was carried out between September and December 2017. Read More

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http://dx.doi.org/10.1016/j.jsps.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362272PMC
February 2019
2 Reads

Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance

Turk J Med Sci 2019 Feb 11;49(1):347-355. Epub 2019 Feb 11.

Background/aim: Ankaferd hemostat (ABS; Ankaferd blood stopper, İstanbul, Turkey) is a folkloric medicinal plant extract. The aim of this study was to determine the effect of Ankaferd hemostat (ABS) on the fate of Helicobacter pylori strains. The study also aims to determine alterations in the antimicrobial resistance of three different H. Read More

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http://dx.doi.org/10.3906/sag-1807-206DOI Listing
February 2019
2 Reads
0.841 Impact Factor

Helicobacter pylori and nutrition: a bidirectional communication.

Minerva Gastroenterol Dietol 2019 Feb 12. Epub 2019 Feb 12.

Unit of Dietetics and Clinical Nutrition, Città della Salute e della Scienza, Turin, Italy.

Helicobacter pylori (HP) is a gram negative flagellated pathogen acid-resistant bacterium; it belongs to the order Campylobacterales that is wide spread all over the world, infecting more than 50% of the world population. HP infection is etiologically associated with non-atrophic and atrophic gastritis, peptic ulcer and with 3 to 6-fold increased relative risk for developing gastric adenocarcinoma and mucosa-associated lymphoid tissue (MA LT) lymphoma. For this reason HP is recognized by the World Health Organization as a Class I human carcinogen. Read More

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https://www.minervamedica.it/index2.php?show=R08Y9999N00A190
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http://dx.doi.org/10.23736/S1121-421X.19.02568-6DOI Listing
February 2019
9 Reads

Rifabutin-Based Rescue Therapy for Eradication: A Long-Term Prospective Study in a Large Cohort of Difficult-to-Treat Patients.

J Clin Med 2019 Feb 6;8(2). Epub 2019 Feb 6.

Unit of Gastroenterology, Molinette Hospital, 10123 Turin, Italy.

The most commonly used regimens fail to eradicate () infection in 5⁻10% of patients. Those not cured with treatments based on amoxicillin, clarithromycin, nitroimidazoles, fluoroquinolones, bismuth or tetracycline have no other conventional options thereafter. In this prospective long-term monocentric study, patients who failed to eradicate following treatment with all conventional antibiotics were included. Read More

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http://dx.doi.org/10.3390/jcm8020199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406425PMC
February 2019
2 Reads

Helicobacter pylori infection promotes autophagy through Nrf2-mediated heme oxygenase upregulation in human gastric cancer cells.

Biochem Pharmacol 2019 Apr 4;162:89-97. Epub 2019 Feb 4.

Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul 08826, South Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Sciences and Technology, Seoul National University, Seoul 08826, South Korea; Cancer Research Institute, Seoul National University, Seoul 03080, South Korea. Electronic address:

It has been reported that Helicobacter pylori (H. pylori) infection is one of the primary causes of gastritis and peptic ulcer diseases. More than 50% of the world's population is supposed to be infected by this bacterium. Read More

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http://dx.doi.org/10.1016/j.bcp.2019.02.003DOI Listing
April 2019
1 Read

Comorbid for gastroduodenal ulcers in the aspect of calcium imbalance and blockers of slow calcium channels in their treatment.

Authors:
L A Fomina

Ter Arkh 2018 Feb;90(2):28-34

Tver State Medical University, Ministry of Health of Russia, Tver, Russia.

Aim: Find out the calcium content of the blood reflecting its balance and functional status the calcium regulatory system when it is comorbid for gastroduodenal ulcers (GDU), developed on the background of chronic erosive gastritis (CEG), chronic erosive duodenitis (CED), arterial hypertension (AH) and osteo-articular pathology with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), and the impact of his changes on the activity ulzerogennogo process, the state of regional microcirculation and the functions of the stomach. To determine the pathogenetic justification for and effectiveness of blockers of slow calcium channels (BSCaC) in complex treatment.

Materials And Methods: Examined 132 patients with GDU. Read More

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http://dx.doi.org/10.26442/terarkh201890228-34DOI Listing
February 2018
3 Reads

The Association of Gastritis and Peptic Ulcer With Polymorphisms in the Inflammatory-related Genes IL-4 and IL-10 in Iranian Population.

Iran J Pathol 2018 17;13(2):229-236. Epub 2018 Jul 17.

Dept. of Medical Genetics, Hormozgan University of Medical Science, Bandarabas, Iran.

Background & Objective: The current study aimed at assessing the relationship between gastritis and peptic ulcer susceptibility and inflammation-related gene polymorphisms in Iranian patients.Gastritis and peptic ulcer are common medical complications with serious outcomes on the quality of life. Inflammatory responses of gastric mucosa are associated with helicobacter pylori, but most infected patients remain asymptomatic. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339493PMC
July 2018
2 Reads

Helicobacter pylori vacA, cagA and iceA genotypes in dyspeptic patients from southwestern region, Saudi Arabia: distribution and association with clinical outcomes and histopathological changes.

BMC Gastroenterol 2019 Jan 25;19(1):16. Epub 2019 Jan 25.

Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.

Background: The aim of this study was to identify the common H. pylori virulence genes among dyspeptic Southwestern Saudi patients and their association with clinical outcomes and histopathological findings to help practitioners and researchers in the region for better management of infections caused by such bacteria.

Methods: Four hundred two gastric biopsy specimens were analyzed using histopathological examination and real time-PCR. Read More

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http://dx.doi.org/10.1186/s12876-019-0934-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346553PMC
January 2019
4 Reads

Efficacy and safety of Syferol-IHP for the treatment of peptic ulcer disease: a pilot, double-blind randomized trial.

Clin Exp Gastroenterol 2019 15;12:21-30. Epub 2019 Jan 15.

Biomedicine Research Group, Nnamdi Azikiwe University, Awka, Nigeria,

Background: To our knowledge, there is no prior randomized study on the utility of Syferol-IHP (blend of virgin coconut oil and oil) when coadministered with a triple therapy schedule.

Aim: This study determined the efficacy and safety of Syferol-IHP as adjunct to conventional triple therapy for the treatment of peptic ulcer disease (PUD).

Methods: A pilot double-blind randomized trial was conducted in patients with confirmed diagnosis (endoscopy-guided biopsy) of PUD. Read More

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https://www.dovepress.com/efficacy-and-safety-of-syferol-ihp
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http://dx.doi.org/10.2147/CEG.S178179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338118PMC
January 2019
7 Reads

BST-104, a Water Extract of Lonicera japonica, Has a Gastroprotective Effect via Antioxidant and Anti-Inflammatory Activities.

J Med Food 2019 Feb 24;22(2):140-151. Epub 2019 Jan 24.

3 Department of Research, GREEN CROSS Wellbeing Co., Ltd., Seongnam, South Korea.

The gastroprotective effects of BST-104 (a water extract of Lonicera japonica) and the mechanisms involved were investigated in murine models of gastritis and peptic ulcer. The gastroprotective effects of BST-104 and its active components were evaluated in rat models of HCl/ethanol-induced gastritis and acetic acid-induced gastric ulcer. After orally administering BST-104, chlorogenic acid, rebamipide (positive control), or vehicle to each animal model, gastric lesion sizes, gastric mucus statuses, proinflammatory cytokine levels, and oxidative stress were measured. Read More

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https://www.liebertpub.com/doi/10.1089/jmf.2018.4231
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http://dx.doi.org/10.1089/jmf.2018.4231DOI Listing
February 2019
8 Reads

Lactobacillus reuteri DSM 17938 Protects against Gastric Damage Induced by Ethanol Administration in Mice: Role of TRPV1/Substance P Axis.

Nutrients 2019 Jan 21;11(1). Epub 2019 Jan 21.

Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (Lafidg), Federal University of Piauí, Av. São Sebastião, nº 2819, CEP 64202-02, Parnaíba, PI, Brazil.

This study aimed to evaluate the effect of DSM 17938 (DSM) on ethanol-induced gastric injury, and if its possible mechanism of action is related to inhibiting the transient receptor potential vanilloid type 1 (TRPV1). We evaluated the effect of supplementing 10⁸ CFU•g body wt•day of DSM on ethanol-induced gastric injury. DSM significantly reduced the ulcer area (1. Read More

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http://dx.doi.org/10.3390/nu11010208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356937PMC
January 2019
3 Reads

Helicobacter pylori infection associated with an increased risk of colorectal adenomatous polyps in the Chinese population.

BMC Gastroenterol 2019 Jan 21;19(1):14. Epub 2019 Jan 21.

Statistical Genomics and Data Analysis Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.

Background: Gastric Helicobacter pylori (H. pylori) is linked with chronic gastritis, peptic ulcer disease, and gastric malignancy. This study aims to investigate the association of gastric H. Read More

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http://dx.doi.org/10.1186/s12876-018-0918-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341657PMC
January 2019
2 Reads

Virulence factor genotyping of Helicobacter pylori isolated from Costa Rican dyspeptic patients.

Microb Pathog 2019 Mar 14;128:276-280. Epub 2019 Jan 14.

Institute for Health Research (INISA), University of Costa Rica, San Pedro, 11501, San José, Costa Rica. Electronic address:

Background And Aims: Costa Rica is one of the countries with the highest incidence and mortality rates for gastric cancer. Helicobacter pylori infection rates are high in the whole country. We have previously shown that H. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08824010183095
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http://dx.doi.org/10.1016/j.micpath.2019.01.018DOI Listing
March 2019
12 Reads
2.000 Impact Factor

The lipoprotein HP1454 of Helicobacter pylori regulates T-cell response by shaping T-cell receptor signalling.

Cell Microbiol 2019 May 31;21(5):e13006. Epub 2019 Jan 31.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Helicobacter pylori (HP) is a Gram-negative bacterium that chronically infects the stomach of more than 50% of human population and represents a major cause of gastric cancer, gastric lymphoma, gastric autoimmunity, and peptic ulcer. It still remains to be elucidated, which HP virulence factors are important in the development of gastric disorders. Here, we analysed the role of the HP protein HP1454 in the host-pathogen interaction. Read More

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http://dx.doi.org/10.1111/cmi.13006DOI Listing
May 2019
7 Reads
4.915 Impact Factor

Cochlospermum regium (Mart. ex Schrank) Pilg.: Evaluation of chemical profile, gastroprotective activity and mechanism of action of hydroethanolic extract of its xylopodium in acute and chronic experimental models.

J Ethnopharmacol 2019 Apr 3;233:101-114. Epub 2019 Jan 3.

Área de Farmacologia, Departamento de Ciências Básicas em Saúde, Faculdade de Medicina, Universidade Federal de Mato Grosso (UFMT), Cuiabá, Brazil. Electronic address:

Ethnopharmacological Relevance: Cochlospermum regium (Bixaceae) is a native shrub of Brazil and its xylopodium (infusion/decoction) is being used for the treatment of gastritis, ulcers, arthritis, intestinal infections, gynaecological infections, skin diseases, among others. The aim of the present study was to evaluate the gastroprotective/antiulcer activity and the mechanism of action of hydroethanolic extract of C. regium xylopodium (HECr), using in vitro and in vivo models. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183292
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http://dx.doi.org/10.1016/j.jep.2019.01.002DOI Listing
April 2019
19 Reads

Helicobacter pylori Infection and Related Gastrointestinal Diseases in Southeast Asian Countries: An Expert Opinion Survey

Asian Pac J Cancer Prev 2018 Dec 25;19(12):3565-3569. Epub 2018 Dec 25.

Department of Internal Medicine, University of Medicine and Pharmacy at Hochiminh City, Hochiminh, Vietnam.

Background: Helicobacter pylori (H. pylori) infection is currently considered as an infectious disease irrespective of symptoms and stage of disease. This study aimed to survey the impact of H. Read More

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http://dx.doi.org/10.31557/APJCP.2018.19.12.3565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428556PMC
December 2018
3 Reads

Olmesartan-associated severe gastritis and enteropathy.

BMJ Case Rep 2018 Dec 10;11(1). Epub 2018 Dec 10.

Gastroenterology, University Hospital of Llandough, Cardiff, UK.

Olmesartan is an angiotensin II receptor antagonist, used in the treatment of hypertension. We report a case of olmesartan-associated severe gastritis with enteropathy in a 74-year-old woman who presented with mainly upper gastrointestinal symptoms. There was significant endoscopic improvement in the mucosal inflammation on stopping the drug. Read More

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http://dx.doi.org/10.1136/bcr-2018-226133DOI Listing
December 2018
1 Read

From Sidney to OLGA: an overview of atrophic gastritis.

Acta Biomed 2018 Dec 17;89(8-S):93-99. Epub 2018 Dec 17.

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Chronic gastritis is a long-lasting disease that can lead to a loss of appropriate gastric glands. Gastritis, as term, apply to an inflammation of the stomach, histologically proven, sometimes with structural mucosal changes. Worldwide Helicobacter pylori's infection play a pivotal role as the main etiological effector of chronic active gastritis. Read More

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http://dx.doi.org/10.23750/abm.v89i8-S.7946DOI Listing
December 2018
3 Reads

Helicobacter pylori, transmission routes and recurrence of infection: state of the art.

Acta Biomed 2018 Dec 17;89(8-S):72-76. Epub 2018 Dec 17.

Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.

Helicobacter pylori (H. pylori) infection is one of the most common infection in humans, affecting more than half of the population. The prevalence of the infection varies widely in rural developing areas (more than 80%) compared to urban developed ones (less than 40%), as a consequence of different socioeconomic and hygienic conditions. Read More

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http://dx.doi.org/10.23750/abm.v89i8-S.7947DOI Listing
December 2018
20 Reads

Relationship between Helicobacter pylori infection and GERD.

Acta Biomed 2018 Dec 17;89(8-S):40-43. Epub 2018 Dec 17.

Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.

Gastroesophageal reflux disease (GERD) is due to the chronic exposure of the esophageal mucosa to acid secretion from the stomach. Helicobacter pylori (H.p. Read More

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http://dx.doi.org/10.23750/abm.v89i8-S.7918DOI Listing
December 2018
3 Reads

MicroRNA‑146a inhibits the inflammatory responses induced by interleukin‑17A during the infection of Helicobacter pylori.

Mol Med Rep 2019 Feb 5;19(2):1388-1395. Epub 2018 Dec 5.

Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China.

Helicobacter pylori (H. pylori) infection is the major cause of chronic active gastritis and peptic ulcer disease. Upregulation of IL‑17A is associated with H. Read More

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http://dx.doi.org/10.3892/mmr.2018.9725DOI Listing
February 2019
3 Reads

The value of oral contrast ultrasonography in the diagnosis of gastric cancer in elderly patients.

World J Surg Oncol 2018 Dec 7;16(1):233. Epub 2018 Dec 7.

Department of Ultrasonography, Chongming branch of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 25 South Gate Road, Cheng Qiao Town, Chongming District, Shanghai, 202150, China.

Background: This study aims to investigate the value of oral contrast ultrasonography (OCUS) in the diagnosis of gastric cancer in elderly patients.

Methods: OCUS data obtained from patients ≥ 60 years old were retrospectively analyzed and compared with gastroscopy results.

Results: Among the 12,716 subjects examined by OCUS, 5021 subjects were ≥ 60 years old, which accounted for 39. Read More

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http://dx.doi.org/10.1186/s12957-018-1527-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286526PMC
December 2018
4 Reads

Clinical features of Helicobacter pylori antibody-positive junior high school students in Nagano Prefecture, Japan.

Helicobacter 2019 Apr 4;24(2):e12559. Epub 2018 Dec 4.

Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan.

Background: Previously, we conducted an epidemiological study screening for Helicobacter pylori antibody positivity among Japanese junior high school students. In this study, we updated the epidemiological data and assessed the clinical features of H pylori antibody-positive junior high school students.

Materials And Methods: We assessed H pylori antibody-positive subjects who were identified between 2012 and 2015 at four junior high schools in Nagano Prefecture, Japan. Read More

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http://dx.doi.org/10.1111/hel.12559DOI Listing
April 2019
8 Reads

Correlation between expression of MMP-9 and MMP-3 in Helicobacter pylori infected patients with different gastroduodenal diseases.

Arab J Gastroenterol 2018 Dec 30;19(4):148-154. Epub 2018 Nov 30.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address:

Background And Study Aims: Helicobacter pylori (H. pylori) has been implicated in the pathogenesis of most important gastro-duodenal diseases, such as gastritis, peptic ulcer disease (PUD) and gastric cancer. H. Read More

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http://dx.doi.org/10.1016/j.ajg.2018.11.001DOI Listing
December 2018
2 Reads

Recent trends in the prevalence of Helicobacter Pylori in symptomatic children: A 12-year retrospective study in a tertiary centre.

J Pediatr Surg 2019 Feb 6;54(2):255-257. Epub 2018 Nov 6.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China. Electronic address:

Objective: Helicobacter pylori infection is common among Asians. However, evidence in the recent years has demonstrated a decrease in the prevalence of H. pylori infection among children and adults worldwide. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.10.079DOI Listing
February 2019
4 Reads

Roles of Cholesteryl-α-Glucoside Transferase and Cholesteryl Glucosides in Maintenance of Helicobacter pylori Morphology, Cell Wall Integrity, and Resistance to Antibiotics.

MBio 2018 11 27;9(6). Epub 2018 Nov 27.

Pathogen Biology Laboratory, Department of Biotechnology and Bioinformatics, University of Hyderabad, Hyderabad, India

Infection of the human stomach caused by is very common, as the pathogen colonizes more than half of the world's population. It is associated with varied outcomes of infection, such as peptic ulcer disease, gastric ulcers, and mucosa-associated lymphoid tissue lymphoma, and is generally considered a risk factor for the development of gastric adenocarcinoma. Cholesteryl glucosides (CGs) constitute a vital component of the cell wall of and contribute to its pathogenicity and virulence. Read More

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http://dx.doi.org/10.1128/mBio.01523-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282200PMC
November 2018
4 Reads

Designing a novel ELISA method based on recombinant antigens to increase sensitivity and specificity of whole cell antigen detection.

Gastroenterol Hepatol Bed Bench 2018 ;11(4):333-342

Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Aim: In this research, we designed a direct Enzyme Linked Immunoassay method to detect antigens in stool specimens.

Background: infection as the worldwide problem is related to many gastrointestinal disorders such as gastritis, gastric cancer, non-ulcer disease, peptic ulcer disease and duodenal ulcer.

Methods: We produced and purified recombinant and antigens in and extracted their antibodies from a panel of positive sera specimens. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204246PMC
January 2018
24 Reads

Helicobacter pylori outer membrane vesicles involvement in the infection development and Helicobacter pylori-related diseases.

J Biomed Sci 2018 Nov 8;25(1):78. Epub 2018 Nov 8.

Laboratory of Gastroimmunology, Department of Immunology and Infectious Biology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237, Łódź, Poland.

Helicobacter pylori - (H. pylori) play a role in the pathogenesis of gastritis, gastric and duodenal ulcers as well as gastric cancer. A possible involvement of outer membrane vesicles (OMVs) produced by H. Read More

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https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929
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http://dx.doi.org/10.1186/s12929-018-0480-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225681PMC
November 2018
15 Reads

Is There a Reason for the Proton Pump Inhibitor? An Assessment of Prescribing for Residential Care Patients in British Columbia.

Can J Hosp Pharm 2018 Sep-Oct;71(5):295-301. Epub 2018 Oct 31.

, BSc(Pharm), PharmD, is with Lower Mainland Pharmacy Services, Surrey British Columbia, and the Therapeutics Initiative (The University of British Columbia), Vancouver, British Columbia.

Background: The use of proton pump inhibitors (PPIs) may cause significant harm to patients in the residential care setting, as these patients are often frail with multiple morbidities. The extent of non-evidence-based use of PPIs in residential care sites of the Fraser Health Authority in British Columbia is unknown.

Objective: To determine the proportion of non-evidence-based use of PPI therapy for residential care patients of the Fraser Health Authority. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209499PMC
October 2018
7 Reads

Pediatric Gastritis, Gastropathy, and Peptic Ulcer Disease.

Pediatr Rev 2018 Nov;39(11):542-549

Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Nicklaus Children's Hospital, Miami, FL.

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http://pedsinreview.aappublications.org/lookup/doi/10.1542/p
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http://dx.doi.org/10.1542/pir.2017-0234DOI Listing
November 2018
6 Reads

ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats.

J Vet Intern Med 2018 Nov 31;32(6):1823-1840. Epub 2018 Oct 31.

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Texas A & M University, College Station, Texas.

The gastrointestinal (GI) mucosal barrier is continuously exposed to noxious toxins, reactive oxygen species, microbes, and drugs, leading to the development of inflammatory, erosive, and ultimately ulcerative lesions. This report offers a consensus opinion on the rational administration of GI protectants to dogs and cats, with an emphasis on proton pump inhibitors (PPIs), histamine type-2 receptor antagonists (H RAs), misoprostol, and sucralfate. These medications decrease gastric acidity or promote mucosal protective mechanisms, transforming the management of dyspepsia, peptic ulceration, and gastroesophageal reflux disease. Read More

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http://dx.doi.org/10.1111/jvim.15337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271318PMC
November 2018
13 Reads

Efficacy of compound tablets combined with quadruple therapy for eradication and its correlation with pH value in the stomach: a study protocol of a randomised, assessor-blinded, single-centre study.

BMJ Open 2018 Oct 28;8(10):e023131. Epub 2018 Oct 28.

Department of Gastroenterology, Chongqing University Cancer Hospital &Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.

Introduction: (Hp) is an important pathogenic factor for chronic gastritis, peptic ulcer, gastric cancer, gastric mucosa-associated lymphoid tissue lymphoma and other diseases. In China, the Hp infection rate is high, but the eradication rate is decreasing. A large number of literatures have shown that the addition of can improve the Hp eradication rate and reduce the side effects of antibiotic treatments. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02313
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http://dx.doi.org/10.1136/bmjopen-2018-023131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224731PMC
October 2018
14 Reads

Diagnosis of Infection in Children and Adolescents in Korea.

Pediatr Gastroenterol Hepatol Nutr 2018 Oct 10;21(4):219-233. Epub 2018 Oct 10.

Department of Pediatrics, Gyeongsang National Institute of Health Sciences, Gyeongsang National University College of Medicine, Jinju, Korea.

plays an important role in the pathogenesis of chronic gastritis, peptic ulcer disease, gastric cancer, and gastric mucosa-associated lymphoid tissue lymphoma. In Korea, the guidelines for the diagnosis and treatment of infection in adults were revised in 2013. The European Helicobacter and Microbiota Study Group and Consensus panel released the fifth edition of the Maastricht Consensus Report for the management of infection in 2015, and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the North American Society of Paediatric Gastroenterology, Hepatology and Nutrition released the updated joint guidelines for children and adolescents in 2016. Read More

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http://dx.doi.org/10.5223/pghn.2018.21.4.219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182473PMC
October 2018
4 Reads

Gastrinoma of Cystic Duct: A Rare Association With Multiple Endocrine Neoplasia Type 1.

J Clin Med Res 2018 Nov 9;10(11):843-847. Epub 2018 Oct 9.

Department of Internal Medicine and Endocrine Unit, Medical School and Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Neuroendocrine tumors (NETs) of cystic duct are extremely rare, accounting for less than 2% of NET cases. The association of biliary tree NET and multiple endocrine neoplasm type 1 (MEN1) are even more rare. In this report, we described a case of a 65-year-old woman who was referred to our neuroendocrine outpatient clinic to investigate MEN1 after an incidental diagnosis of gastrinoma. Read More

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http://www.jocmr.org/index.php/JOCMR/article/view/3541
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http://dx.doi.org/10.14740/jocmr3541wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188020PMC
November 2018
20 Reads

Association of and Polymorphisms in Chronic Gastritis and Peptic Ulcer.

Iran J Public Health 2018 Sep;47(9):1364-1370

Center for Research of Molecular Medicine, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran.

Background: are the main cause of chronic inflammation and peptic ulcer. We aimed to determine if 3954 and polymorphisms are associated with the risk of chronic gastritis and peptic ulcer in Iranian population.

Methods: In this case-control study, from 198 individuals enrolled by Mohammadi Hospital, Bandar Abbas, southern Iran from 2012 to 2014 and who showed the symptoms of chronic gastritis and 84 with peptic ulcer participated in the case group, two biopsies were taken from the body, antrum, or ulcer edge of each patient. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174059PMC
September 2018
6 Reads

Burden of gastrointestinal and liver diseases in India, 1990-2016.

Indian J Gastroenterol 2018 Sep 10;37(5):439-445. Epub 2018 Oct 10.

Gastrointestinal Epidemiology Research Center, Division of Gastroenterology, Hepatology and Department of Epidemiology, Johns Hopkins University, 600 N Wolfe St, Blalock 406, Baltimore, MD, 21287, USA.

There is no comprehensive report on the burden of gastrointestinal (GI) and liver diseases in India. In this study, we estimated the age-standardized prevalence, mortality, and disability adjusted life years (DALY) rates of GI and liver diseases in India from 1990 to 2016 using data from the Global Burden of Disease (GBD) Study, which systematically reviews literature and reports for international disease burden trends. Despite a decrease in the overall burden from GI infectious disorders since 1990, they still accounted for the majority of DALYs in 2016. Read More

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http://link.springer.com/10.1007/s12664-018-0892-3
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http://dx.doi.org/10.1007/s12664-018-0892-3DOI Listing
September 2018
16 Reads

Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition?

Can J Infect Dis Med Microbiol 2018 10;2018:6237239. Epub 2018 Sep 10.

Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University, Rome, Italy.

() is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Read More

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http://dx.doi.org/10.1155/2018/6237239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151681PMC
September 2018
7 Reads

Prevalence and factors associated with H. pylori infection in Saudi patients with dyspepsia.

Electron Physician 2018 Sep 9;10(9):7279-7286. Epub 2018 Sep 9.

Associate Professor, Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.

Background: Helicobacter pylori (H. pylori) is a major cause of peptic ulcer disease (PUD) and chronic active gastritis that may progress to gastric cancer. Globally, it has been estimated that 50% or more of the world's population is infected by H. Read More

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http://dx.doi.org/10.19082/7279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140988PMC
September 2018
10 Reads