10,124 results match your criteria Gastritis Chronic


Routine Histopathologic Examination of the Resected Specimen after Laparoscopic Sleeve Gastrectomy- what can be expected?

Acta Chir Belg 2020 Jul 9:1-16. Epub 2020 Jul 9.

Department of General Surgery, Cantonal Hospital Lucerne, Spitalstrasse, CH-6000 Lucerne 16, Switzerland.

Background: Laparoscopic Sleeve Gastrectomy (LSG) is nowadays an established bariatric procedure. Although preoperative gastroscopy is recommended to rule out severe pathologies, there is little evidence about the role of routine histopathologic examination of resected specimens.We sought to identify the prevalence of histopathological relevant findings in patients undergoing LSG and to evaluate their impact in clinical practice. Read More

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Immune Checkpoint Inhibitor-Induced Upper Gastrointestinal Tract Inflammation Shows Morphologic Similarities to, but Is Immunologically Distinct From, Gastritis and Celiac Disease.

Arch Pathol Lab Med 2020 Jul 6. Epub 2020 Jul 6.

From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.

Context.—: Immune checkpoint inhibitor (CPI) therapies are associated with multi-organ immune-related adverse events. Although colonic mucosal changes have been described, inflammatory changes incited by CPIs in the upper gastrointestinal tract have not been well characterized. Read More

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http://dx.doi.org/10.5858/arpa.2019-0700-OADOI Listing

[Systematic review and Meta-analysis of efficacy and safety of Xiangsha Yangwei Pills in treatment of chronic gastritis].

Zhongguo Zhong Yao Za Zhi 2020 Jun;45(11):2668-2676

Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.

To systematically evaluate the efficacy and safety of Xiangsha Yangwei Pills in the treatment of chronic gastritis. Compu-ter retrieval was performed for Cochrane Library, Medline, EMbase, China Knowledge Network Database(CNKI), China Biomedical Literature Service System(SinoMed), Chongqing Weipu Chinese Science and Technology Journal Database(VIP) and WanFang Database(WanFang) randomized controlled trials about Xiangsha Yangwei Pills combined with Western medicine in the treatment of chro-nic gastritis. The retrieval time ranged from the establishment of the library to April 26, 2019. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20200102.502DOI Listing

The relationship between Helicobacter pylori and chronic kidney disease: update 2020.

Minerva Gastroenterol Dietol 2020 Jul 3. Epub 2020 Jul 3.

Renal Transplantation Center "A. Vercellone", Division of Nephrology Dialysis and Transplantation, Department of Medical Sciences, Città della Salute e della Scienza Hospital, University of Turin, Turin, Italy.

A number of studies has confirmed that the epidemiology of Helicobacter pylori (H. pylori) is changing worldwide, with a decrease especially in developed Countries. Nevertheless, since this Gram-negative bacterium infects almost 50% of the world's population, it remains a global problem. Read More

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http://dx.doi.org/10.23736/S1121-421X.20.02729-4DOI Listing

Helicobacter pylori gastric infection in patients with laryngeal cancer and chronic laryngitis.

Eur Arch Otorhinolaryngol 2020 Jul 3. Epub 2020 Jul 3.

Department of ENT, Head and Neck Surgery, General Hospital "Dr. Josip Benčević", Andrije Štampara 42, 35000, Slavonski Brod, Croatia.

Background: The purpose of this study was to investigate the pathohistological status of mucous lining infected with Helicobacte pylori as the possible cause of chronic laryngitis and laryngeal carcinoma.

Materials And Methods: The prospective examination included 51 patients suffering from planocellular laryngeal cancer and 26 examinees suffering from chronic laryngitis. The examinees and the control group were subjected to esophagogastroduodenoscopy which described the local status of the esophagus and stomach. Read More

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http://dx.doi.org/10.1007/s00405-020-06172-8DOI Listing

Russell Body Gastroesophagitis Concurrent With Barrett's Esophagus.

Anticancer Res 2020 Jul;40(7):3991-3994

Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO, U.S.A.

Background: Russell body gastroesophagitis is a rare entity characterized by the accumulation of immunoglobulins within the cytoplasm of plasma cells.

Case Report: Here, we present the case of a 41-year-old male with history of gastroesophageal reflux disease who presented with nausea, vomiting, and altered mental status. Candida esophagitis was noted on upper endoscopy. Read More

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http://dx.doi.org/10.21873/anticanres.14392DOI Listing

Artificial intelligence in gastric cancer: a systematic review.

J Cancer Res Clin Oncol 2020 Jul 1. Epub 2020 Jul 1.

Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, China.

Objective: This study aims to systematically review the application of artificial intelligence (AI) techniques in gastric cancer and to discuss the potential limitations and future directions of AI in gastric cancer.

Methods: A systematic review was performed that follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Pubmed, EMBASE, the Web of Science, and the Cochrane Library were used to search for gastric cancer publications with an emphasis on AI that were published up to June 2020. Read More

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http://dx.doi.org/10.1007/s00432-020-03304-9DOI Listing

Three Cases of Diffuse, Intense Stomach Uptake on DOTATATE PET.

Clin Nucl Med 2020 Jun 25. Epub 2020 Jun 25.

Division of Endocrinology, UCLA David Geffen School of Medicine, Los Angeles, CA.

Incidental tracer uptake on DOTATATE PET is increasingly encountered in clinical practice. We describe 3 patients with suspected or known neuroendocrine tumor who were found to have diffuse and intense stomach uptake on DOTATATE PET. All patients underwent esophagogastroduodenoscopy and/or endoscopic ultrasound; the cause of the stomach uptake was attributed to proton-pump inhibitor use, chronic gastritis, and gastrinoma, respectively. Read More

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http://dx.doi.org/10.1097/RLU.0000000000003153DOI Listing

Relation of cyclooxygenase-2 expression with premalignant gastric lesions.

Acta Gastroenterol Belg 2020 Apr-Jun;83(2):249-254

Department of Pathology, University of Health Sciences Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey.

Introduction: We studied the relation between premalignant gastric lesions and cyclooxygenase-2 (COX-2) expression.

Methods: The study included 254 patients, who were histo- logically diagnosed with chronic active gastritis, atrophy, dys- plasia and metaplasia. Gastric biopsy specimens of the patients were histopathologically examined in terms of the presence of Helicobacter pylori (H. Read More

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Iron Overload in Gastric Mucosa: Underdiagnosed Condition Rarely Documented in Clinical and Pathology Reports.

Cureus 2020 May 22;12(5):e8234. Epub 2020 May 22.

Pathology, ASST Rhodense, Garbagnate Milanese, ITA.

The iron-deficiency anemia is a common disorder worldwide. It is widely treated with oral iron supplements as ferrous sulfate compound in pill or tablet form, and continuous therapy can induce gastric diseases. The diagnosis of this unusual drug-induced disease is based on the endoscopic findings and the histopathological biopsy examination, because the clinical symptoms are vague and non-specific. Read More

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http://dx.doi.org/10.7759/cureus.8234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316405PMC

Can mean platelet volume IndIcate posItIvIty and severIty of gastrIc InflammatIon? An orIgInal study and revIew of the lIterature.

Authors:
Tarik Akar

Acta Clin Croat 2019 Dec;58(4):576-582

Bülent Ecevıt Unıversity Medical Faculty, Department of Gastroenterology, Zonguldak, Turkey.

() is a common problem and a significant cause of chronic gastric inflammation. , ongoing gastric inflammation and its severity are the most critical component of precursors of gastric cancer. Hypothetically, every chronic tissue injury activates platelets, and the mean platelet volume (MPV) reflects this action well. Read More

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http://dx.doi.org/10.20471/acc.2019.58.04.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314311PMC
December 2019

Associations of the -238(G/A) and -308(G/A) TNF-α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.

Asian Pac J Cancer Prev 2020 Jun 1;21(6):1623-1629. Epub 2020 Jun 1.

Helicobacter Pylori and Gastric Pathologies Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.

Objective: Helicobacter pylori (H. pylori) induces the production of tumor necrosis factor-alpha (TNF-α), which is closely related to a gastric epithelial injury. TNF-α gene polymorphism and TNF-α serum levels are associated with various malignant conditions. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.6.1623DOI Listing

Urticaria and the gut.

Curr Opin Allergy Clin Immunol 2020 Aug;20(4):381-385

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology and Allergy, Allergy Center Charité, Berlin, Germany.

Purpose Of Review: To review recent evidence on the association of urticaria and the gut diseases, focusing on the roles of chronic inflammation with or without Helicobacter pylori (H. Pylori) infection.

Recent Findings: The connection between the gut and urticaria has been discussed for a long time. Read More

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http://dx.doi.org/10.1097/ACI.0000000000000653DOI Listing

High rates of clarithromycin and levofloxacin resistance of Helicobacter pylori in patients with chronic gastritis in the South East area of Vietnam.

J Glob Antimicrob Resist 2020 Jun 23. Epub 2020 Jun 23.

Hue University of Medicine and Pharmacy, Hue University, Vietnam. Electronic address:

Objectives: The increasing rates of CLR- and LVX-resistantH. pylori are the main causes of the considerable decrease in the eradication rates of triple therapy and LVX-based regimens. The aims of this study were to determine the rates of CLR- and LVX-resistant H. Read More

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http://dx.doi.org/10.1016/j.jgar.2020.06.007DOI Listing

Dysregulated Expression of Apoptosis-Associated Genes and MicroRNAs and Their Involvement in Gastric Carcinogenesis.

J Gastrointest Cancer 2020 Jun 24. Epub 2020 Jun 24.

Universidade do Sagrado Coração (USC), Bauru, São Paulo, Brazil.

Purpose: Analyze the expression of caspase-9, Smac/DIABLO, XIAP, let-7a, and let-7b in patients with normal gastric tissue, chronic gastritis, and gastric adenocarcinoma.

Methods: The expression of caspase-9, Smac/DIABLO, XIAP, let-7a, and let-7b by qRT-PCR was analyzed in 158 samples from 53 patients with normal gastric mucosa, 86 with chronic gastritis, and 19 with gastric cancer.

Results: The comparison between the gastric cancer and the control group revealed a decreased expression of caspase-9 in gastric cancer tissues; considering the Helicobacter pylor presence, comparable results were revealed. Read More

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http://dx.doi.org/10.1007/s12029-019-00353-3DOI Listing

A Summertime Stupor.

Cureus 2020 May 22;12(5):e8242. Epub 2020 May 22.

Internal Medicine, University of Arizona, Tucson, USA.

Most commonly seen with alcohol use disorder in the developed world, Wernicke's encephalopathy (WE), a disorder caused by thiamine deficiency can be readily missed in the setting of other predisposing conditions such as malnutrition, the most common cause worldwide. We present a case of a 21-year-old female with sudden progressive decline in her level of alertness and mentation along with severe hypothermia who had clinical features and imaging findings consistent with WE in the setting of pancreatitis and chronic gastritis. WE should be suspected in all patients who present with altered mental status (AMS) and who are at an increased risk of malnutrition despite a normal or high body mass index, so that treatment with thiamine may be initiated and further neurologic sequelae can be averted. Read More

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http://dx.doi.org/10.7759/cureus.8242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306676PMC

An improved quantitative real-time polymerase chain reaction technology for Helicobacter pylori detection in stomach tissue and its application value in clinical precision testing.

BMC Biotechnol 2020 Jun 22;20(1):33. Epub 2020 Jun 22.

Department of Clinical Microbiology and Immunology, Faculty of Pharmacy and Medical Laboratory Sciences, Third Military Medical University (Army Medical University), No. 30 Gaotanyan Street, Chongqing, 400038, People's Republic of China.

Background: Helicobacter pylori (H. pylori) infection is a serious human health threat. The empiric H. Read More

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http://dx.doi.org/10.1186/s12896-020-00624-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310109PMC

Analysis of the Relation between Periodontitis and Chronic Gastritis/Peptic Ulcer: A Cross-Sectional Study Using KoGES HEXA Data.

Int J Environ Res Public Health 2020 Jun 18;17(12). Epub 2020 Jun 18.

Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong 18450, Korea.

The aim of the present study was to investigate the association between periodontitis and chronic gastritis/peptic ulcer using a cross-sectional study design. The present prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study (KoGES) recorded from 2004 to 2016. Among 173,209 participants, 9983 with periodontitis and 125,336 with no periodontitis were selected. Read More

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http://dx.doi.org/10.3390/ijerph17124387DOI Listing

Palmatine ameliorates Helicobacter pylori-induced chronic atrophic gastritis by inhibiting MMP-10 through ADAM17/EGFR.

Eur J Pharmacol 2020 Jun 20;882:173267. Epub 2020 Jun 20.

Department of Pharmacy, Fifth Medical Center of PLA General Hospital, Beijing, 100039, China. Electronic address:

Palmatine (Pal), a plant-based isoquinoline alkaloid, was initially isolated from Coptidis Rhizoma (CR, Huanglian in Chinese) and considered to be a potential non-antibiotic therapeutic agent that can safely and effectively improve Helicobacter pylori (H. pylori) induced chronic atrophic gastritis (CAG). However, underlying mechanisms are unclear. Read More

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http://dx.doi.org/10.1016/j.ejphar.2020.173267DOI Listing

Effects of rebamipide for chronic atrophic gastritis: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2020 Jun;99(25):e20620

Department of Gastroenterology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, China.

Background: Chronic atrophic gastritis (CAG) is defined as an important precancerous disease with high risk of gastric cancer. Rebamipide is a mucosal protective agent widely used in the treatment of chronic gastritis. The aim of this systematic review is to assess the efficacy and safety of rebamipide for the treatment of patients with CAG. Read More

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http://dx.doi.org/10.1097/MD.0000000000020620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310858PMC

Hyposplenism, Hashimoto's Autoimmune Thyroiditis and Overlap Syndrome (Celiac Disease and Autoimmune Hepatitis Type 1).

Am J Med Sci 2020 Apr 25. Epub 2020 Apr 25.

"Carol Davila" University of Medicine and Pharmacy, "Sf. Ioan" Clinical Emergency Hospital, Gastroenterology Department, Bucharest, Romania.

Hyposplenism is associated with autoimmune diseases, inflammatory bowel disease, severe celiac disease, autoimmune thyroiditis, untreated HIV infection and chronic graft-versus-host disease. The aim of this study was to review the existing data on hyposplenism associated with celiac disease and Hashimoto's autoimmune thyroiditis. Our research was based on a clinical case concerning a 41-year-old female who presented with asthenia, fatigue, dyspepsia and chronic diarrhea. Read More

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http://dx.doi.org/10.1016/j.amjms.2020.04.022DOI Listing

Chronic facial pain: different comorbidities and characteristics between neuropathic and nonneuropathic conditions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2020 May 24. Epub 2020 May 24.

School of Arts, Science and Humanities Department; and Neurology Department, Medical School, University of São Paulo, São Paulo, Brazil. Electronic address:

Objective: The aim of this study was to investigate the association between comorbidities and chronic diseases and neuropathic and nonneuropathic orofacial pain diagnoses to suggest subclassifications of disease.

Study Design: This was a cross-sectional, retrospective, case-control study. We evaluated 174 patients with orofacial pain and 132 controls by using a systematic protocol that consisted of medical history and demographic, pain, and orofacial characteristics. Read More

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http://dx.doi.org/10.1016/j.oooo.2020.05.006DOI Listing

Interspecies Differences on Pharmacokinetics of Rebamipide following Oral Administration to Rats and Dogs.

Biopharm Drug Dispos 2020 Jun 18. Epub 2020 Jun 18.

College of pharmacy, Kyungsung University, 309, Suyeong-ro, Nam-gu, Busan, 48434, Republic of Korea.

Rebamipide is widely used in East Asia for the treatment of gastric ulcers, acute gastritis, and exacerbated chronic gastritis. The objective of this study was to investigate the pharmacokinetic properties of rebamipide following single oral administration in rats and dogs. Eleven rats and dogs eafigurea single oral administration of rebamipide (35 mg/kg and 100 mg, respectively). Read More

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http://dx.doi.org/10.1002/bdd.2247DOI Listing

The Role of Helicobacter pylori and Serum Pepsinogen Levels in Metachronous Gastric Cancer After Endoscopic Gastrectomy.

Surg Laparosc Endosc Percutan Tech 2020 Jun 5. Epub 2020 Jun 5.

Department of Gastroenterology, Aviation General Hospital, Beijing, China.

Purpose: The current study aimed to explore the role of Helicobacter pylori (Hp) infection and serum pepsinogen (PG) levels in the occurrence of metachronous gastric cancer after endoscopic gastrectomy.

Materials And Methods: Totally, 50 patients with metachronous gastric cancer, 50 patients with chronic atrophic gastritis and 50 healthy subjects were collected from October 2015 to October 2018. Patients in the gastric cancer group underwent endoscopic gastrectomy. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000810DOI Listing

Clinical experience of use of C-breath tests in oesophagogastroduodenal diseases: selective questions.

Prz Gastroenterol 2020 1;15(2):126-130. Epub 2019 Dec 1.

Department of Internal Medicine No. 1, Bogomolets National Medical University, Kyiv, Ukraine.

Introduction: Motility disorders can be an important factor in the occurrence of symptoms of dyspepsia that consequently require evaluation of clinical significance of noninvasive diagnostic approaches when observing patients with functional dyspepsia (FD), gastroesophageal reflux disease (GERD), and -associated diseases of the stomach and duodenum.

Aim: To determine the relationship between various motility disorders and to improve the diagnostics and treatment with the use of C-urea (UBT) and C-octanoic breath tests (OBT).

Material And Methods: A total of 591 patients, aged 18-83 years, who underwent upper gastrointestinal endoscopy at our department were evaluated. Read More

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http://dx.doi.org/10.5114/pg.2019.90080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294975PMC
December 2019

Epidemiological investigation of infection in elderly people in Beijing.

World J Clin Cases 2020 Jun;8(11):2173-2180

Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Background: The () infection rate in China is approximately 50%. is a pathogenic factor of peptic ulcer and chronic gastritis. In addition, infection may also be associated with a variety of cardiovascular diseases in elderly people, such as arteriosclerosis, coronary heart disease, and cerebral infarction, having deleterious effect on their health. Read More

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http://dx.doi.org/10.12998/wjcc.v8.i11.2173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281052PMC

Changes of the Gastric Mucosal Microbiome Associated With Histological Stages of Gastric Carcinogenesis.

Front Microbiol 2020 29;11:997. Epub 2020 May 29.

Department of Gastroenterology and Hepatology, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.

The changes of gastric microbiome across stages of neoplastic progression remain poorly understood, especially for intraepithelial neoplasia (IN) which has been recognized as a phenotypic bridge between atrophic/intestinal metaplastic lesions and invasive cancer. The gastric microbiota was investigated in 30 healthy controls (HC), 21 non-atrophic chronic gastritis (CG), 27 gastric intestinal metaplasia (IM), 25 IN, and 29 gastric cancer (GC) patients by 16S rRNA gene profiling. The bacterial diversity, and abundances of phyla Armatimonadetes, Chloroflexi, Elusimicrobia, Nitrospirae, Planctomycetes, Verrucomicrobia, and WS3 reduced progressively from CG, through IM, IN to GC. Read More

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http://dx.doi.org/10.3389/fmicb.2020.00997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272699PMC
May 2020
3.941 Impact Factor

Prevalence and Impact: A Histology-Based Report About Children from an Endemic Country.

Int J Gen Med 2020 22;13:207-214. Epub 2020 May 22.

Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, School of Medicine, The University of Jordan, Amman, Jordan.

Background: is spreading worldwide with a high prevalence rate in the developing countries. Our primary goal was to measure the histology-based prevalence of infection in children and to quantify its impact on the gastric inflammation and anemia. Our secondary goal was to study possible predictors for the presence of in this cohort. Read More

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http://dx.doi.org/10.2147/IJGM.S240205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250302PMC

Chronic Gastritis Is Associated with a Decreased High-Density Lipid Level: Histological Features of Gastritis Based on the Updated Sydney System.

J Clin Med 2020 Jun 14;9(6). Epub 2020 Jun 14.

Department of Neurology, Hanyang University College of Medicine, Seoul 04763, Korea.

Chronic gastritis could activate a systemic inflammatory response that could result in adverse lipid profiles. To determine the severity of chronic gastritis, (HP), mononuclear cell (lymphocytes and plasma cells), and neutrophil scores were assessed on the basis of the updated Sydney system (USS), which is widely used for histological grading. The aim of this study was to assess the relationships between gastric histological features and lipid profile levels. Read More

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http://dx.doi.org/10.3390/jcm9061856DOI Listing

Proton Pump Inhibitors in Children: the Good, the Bad, and the Ugly.

Curr Allergy Asthma Rep 2020 Jun 10;20(8):39. Epub 2020 Jun 10.

Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, USA.

Purpose Of Review: The evidence supporting or contesting the prescription of proton pump inhibitors (PPIs) for children and updates on side effects are reviewed.

Recent Findings: PPIs remain an important therapeutic option for esophagitis and gastritis. However, recent studies demonstrate no benefit when prescribing PPIs for chronic cough, infantile reflux, asthma, or functional gastrointestinal disorders. Read More

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http://dx.doi.org/10.1007/s11882-020-00926-4DOI Listing

[Wenweishu Capsule alleviates gastric mucosal lesion in rats with chronic gastritis by inhibiting NF-κB pathway].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2020 Apr;36(4):297-303

Gansu University of Chinese Medicine, Lanzhou 730000, China. *Corresponding author, E-mail:

Objective To investigate the effect of Wenweishu Capsule on the expression of nuclear factor kappa B (NF-κB)-related proteins in chronic gastritis model rats. Methods Wistar rat models of chronic gastritis were constructed by alternant administrations of sodium deoxycholate, ammonia, alcohol solution and the hunger disorder method. The rats were randomly divided into control group, model group, vatacoenayme group, high-, middle- and low-dose Wenweishu Capsule groups. Read More

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New Silver(I) Coordination Compound Loaded into Polymeric Nanoparticles as a Strategy to Improve Anti- Activity.

Mol Pharm 2020 Jul 23;17(7):2287-2298. Epub 2020 Jun 23.

School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, São Paulo, Brazil.

inhabits the gastric epithelium and can promote the development of gastric disorders, such as peptic ulcers, acute and chronic gastritis, mucosal lymphoid tissue (MALT), and gastric adenocarcinomas. To use nanotechnology as a tool to increase the antibacterial activity of silver I [Ag(I)] compounds, this study suggests a new strategy for infections, which have hitherto been difficult to control. [Ag (PhTSC·HCl)] (NO)·HO (compound 1) was synthesized, characterized, and loaded into polymeric nanoparticles (PN1). Read More

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b01264DOI Listing

Malignant Peritoneal Mesothelioma as a Rare Cause of Dyspeptic Complaints and Ascites: A Diagnostic Challenge.

GE Port J Gastroenterol 2020 Apr 8;27(3):197-202. Epub 2019 Oct 8.

Internal Medicine Department, Centro Hospitalar Póvoa de Varzim/Vila do Conde, Póvoa de Varzim, Portugal.

Introduction: Malignant peritoneal mesothelioma (MPM) is a rare malignancy of the mesothelial cells in the peritoneum. The best-defined risk factor is asbestos exposure, but germline mutations in BAP1 also increase susceptibility to this tumor. The diagnosis of MPM is challenging since clinical manifestations are often nonspecific. Read More

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http://dx.doi.org/10.1159/000503075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250362PMC

Chronic Atrophic Gastritis with Negative Intrinsic Factor and Parietal Cell Antibody Presenting as a Severe Hemolytic Anemia.

Case Rep Hematol 2020 15;2020:8697493. Epub 2020 May 15.

Medical University of South Carolina, Department of Internal Medicine, Charleston, SC, USA.

A 28-year-old Caucasian male with Hashimoto's disease and vitiligo presented with two weeks of dizziness on exertion following pharyngitis which was treated with prednisone 40 mg by mouth once a day for five days. Initial workup revealed anemia, elevated lactate dehydrogenase (LDH), and low haptoglobin. He underwent workup for causes of hemolytic anemia which was remarkable for a peripheral blood smear with hypersegmented neutrophils and low vitamin B12 levels concerning for pernicious anemia. Read More

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http://dx.doi.org/10.1155/2020/8697493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245653PMC

The Meaning of Incidental Goblet Cells at the Gastroesophageal Junction.

Dig Dis Sci 2020 Jun 3. Epub 2020 Jun 3.

Division of Gastroenterology, Portland VA Medical Center and Oregon Health & Science University, P3-GI, Portland, OR, 97239, USA.

Background And Aims: The causes for the occurrence of goblet cells at the gastroesophageal junction (GEJ-GC) are unknown. The aim of our study was to compare the concurrent histologic changes of the stomach in (1) patients with GEJ-GC, but without Barrett's esophagus (BE) to those in (2) patients with BE and in (3) controls without GEJ-GC or BE.

Methods: We used an electronic database of histopathologic records from 1. Read More

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http://dx.doi.org/10.1007/s10620-020-06357-5DOI Listing

Chronic Esophagitis and Gastritis After Ingestion of Box Jellyfish (Class Cubozoa).

Hawaii J Health Soc Welf 2020 May;79(5 Suppl 1):135-138

Department of Pediatrics, Madigan Army Medical Center, Tacoma, WA (CMS).

This is a case report of chronic esophagitis and gastritis following the ingestion of box jellyfish () by a 12-year old boy with severe autism spectrum disorder and pica. Biopsies taken at esophagogastroduodenoscopy at two months post ingestion revealed histological evidence of esophagitis and gastritis, which resolved after treatment with H2 receptor agonist and proton pump inhibitor. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260864PMC

Anisakid nematode species identification in harbour porpoises () from the North Sea, Baltic Sea and North Atlantic using RFLP analysis.

Int J Parasitol Parasites Wildl 2020 Aug 20;12:93-98. Epub 2020 May 20.

Institute for Terrestrial and Aquatic Wildlife Research (ITAW), University of Veterinary Medicine, Foundation, Hannover, Werftstrasse 6, 25761, Büsum, Germany.

Harbour porpoises () are the only native cetacean species in the German North and Baltic Seas and the final host of (.) , which infects their first and second gastric compartments and may cause chronic ulcerative gastritis. belongs to the family Anisakidae (Ascaridoidea, Rhabditida) as well as the phocine gastric nematode species (. Read More

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http://dx.doi.org/10.1016/j.ijppaw.2020.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260678PMC

[Study on medication regularity of chronic atrophic gastritis in Beijing-Tianjin-Hebei region based on latent structure model].

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(7):1691-1697

Department of Spleen and Stomach, Hebei Hospital of Traditional Chinese Medicine Shijiazhuang 050011, China.

To explore the etiology, pathogenesis, distribution of syndromes and the rule of medication of chronic atrophic gastritis(CAG) in Beijing-Tianjin-Hebei region based on the latent structure model. Chronic atrophic gastritis of 279 cases in Beijing-Tianjin-Hebei region were extracted from the established database of spleen and stomach diseases of famous veteran Chinese medicine experts. The latent structure models of symptoms and drugs of chronic atrophic gastritis were constructed by using Lantern 3. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20200214.501DOI Listing

Effects of weifuchun tablet for chronic atrophic gastritis: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2020 May;99(22):e20374

Department of Gastroenterology, Tongde Hospital of Zhejiang Province.

Background: Chronic atrophic gastritis (CAG) is defined as an important precancerous disease in the development of gastric cancer. Early intervention of CAG is of great significance in reducing symptoms and blocking its progression to gastric cancer. Weifuchun (WFC) tablet is a classic Chinese patent medicine used to treat CAG. Read More

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http://dx.doi.org/10.1097/MD.0000000000020374DOI Listing

Rewiring of Microbiota Networks in Erosive Inflammation of the Stomach and Small Bowel.

Front Bioeng Biotechnol 2020 13;8:299. Epub 2020 May 13.

Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

The development of non-invasive, inexpensive, and effective early diagnosis tests for gastric and small-bowel lesions is an urgent requirement. The introduction of magnetically guided capsule endoscopy (MGCE) has aided examination of the small bowel for diagnoses. However, the distribution of the fecal microbiome in abnormal erosions of the stomach and small bowel remains unclear. Read More

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http://dx.doi.org/10.3389/fbioe.2020.00299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237573PMC

Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan against -induced gastritis.

J Vet Sci 2020 May;21(3):e39

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.

Background: There are various species colonizing the stomachs of animals. Although usually cause asymptomatic infection in the hosts, clinical signs can occur due to gastritis associated with in animals. Among them, is strongly associated with chronic gastritis, gastric ulcers, and gastric cancers. Read More

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http://dx.doi.org/10.4142/jvs.2020.21.e39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263912PMC

Immunomodulatory treatment for mucosa-associated lymphoid tissue lymphoma (MALT lymphoma).

Hematol Oncol 2020 May 29. Epub 2020 May 29.

Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria.

The pathogenesis of mucosa-associated lymphoid tissue (MALT) lymphoma has been characterized as a dynamic process driven by lymphoma cell dependency on T-cell signaling, chronic antigenic stimulation of marginal zone B-cells and activation of the nuclear factor-kappa B signaling pathway. This concept is underlined by the strong causal connection of chronic Helicobacter pylori associated gastritis and MALT lymphoma development based on perpetual auto-antigenic stimulation of Helicobacter pylori-specific T-cells, but also its association with further potential infectious triggers and autoimmune disorders for extragastric lymphoma sites. Thus, given the dependency of MALT lymphoma cells on the tumor microenvironment, this specific entity appears highly suitable for immunomodulatory treatment strategies. Read More

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http://dx.doi.org/10.1002/hon.2754DOI Listing

Association of infection with colorectal polyps and malignancy in China.

World J Gastrointest Oncol 2020 May;12(5):582-591

Department of Gastroenterology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang Uygur Autonomous Region, China.

Background: Gastric () infection is related to chronic gastritis, gastroduodenal ulcer, and gastric malignancies; whether this infection is related to colorectal polyps and colorectal cancer (CRC), remains debatable.

Aim: To investigate the relationship between gastric infection and the risk of colorectal polyps and CRC.

Methods: We retrospectively analyzed 3872 patients with colorectal polyps who underwent colonoscopy and pathological diagnosis. Read More

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http://dx.doi.org/10.4251/wjgo.v12.i5.582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235179PMC

Characterization and strong risk association of to polymorphism and and their influence on mRNA expression in gastric cancer.

World J Gastrointest Oncol 2020 May;12(5):535-548

Department of Molecular Biology, São José do Rio Preto School of Medicine, São José do Rio Preto, São Paulo 15090-000, Brazil.

Background: Toll-like receptor-2 () is responsible for recognizing () and activating the immune response. Polymorphisms in may modulate gastric carcinogenesis.

Aim: To evaluate whether the (rs3804099) and - (rs111200466) polymorphisms contribute to gastric carcinogenesis in the Brazilian population, and to determine the influence of both polymorphisms and infection on mRNA expression. Read More

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http://dx.doi.org/10.4251/wjgo.v12.i5.535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235183PMC

Gastrointestinal involvement of primary skin diseases.

J Eur Acad Dermatol Venereol 2020 May 26. Epub 2020 May 26.

Center for Research & Development, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan.

Less is known about gastrointestinal (GI) involvement of primary skin diseases due to the difference in embryology, histology, microbiology and physiology between integument and alimentary tract. Oesophagus, following the oropharyngeal mucosa, is the most common GI segment affected by primary skin diseases, especially by eosinophilic oesophagitis, lichen planus and autoimmune bullous dermatoses like pemphigus vulgaris, mucosal membrane pemphigoid and epidermolysis bullosa acquisita. Eosinophilic oesophagitis is an emerging chronic atopic disease with oesophageal dysfunction as the typical presentation, and oesophageal narrowing, rings and stricture as late complications. Read More

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http://dx.doi.org/10.1111/jdv.16676DOI Listing

Bullous pemphigoid-associated chronic atrophic gastritis.

Dermatol Ther 2020 May 24:e13671. Epub 2020 May 24.

Department of Dermatology, Allergology and Venereology, Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1111/dth.13671DOI Listing

A Case of Subacute Combined Degeneration of the Spinal Cord Caused by Autoimmune Gastritis.

Intern Med 2020 May 23. Epub 2020 May 23.

Second Department of Internal Medicine, Osaka Medical College, Japan.

A 68-year-old woman presented with a 2-year history of worsening unsteady gait. Her neurological examination revealed peripheral neuropathy with lower limb sensory dominance. T2-weighted imaging revealed a disorder of the posterior cervical cord. Read More

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http://dx.doi.org/10.2169/internalmedicine.4684-20DOI Listing

[Acupoint catgut embedding improves gastric mucosal injury by down-regulating expression of HIF-1α and VEGF in chronic atrophic gastritis rats].

Zhen Ci Yan Jiu 2020 May;45(5):384-8

Renhe Chinese Medicine Hospital, Foshan 528244, Guangdong Province.

Objective: To observe the effect of acupoint catgut embedding on histopathological changes of gastric mucosa and expression of mucosal hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) proteins in chronic atrophic gastritis (CAG) rats, so as to explore its mechanisms underlying improvement of CAG.

Methods: Male SD rats were divided into blank group (=10) and model group (=9) and catgut embedment group (=10). The CAG model was established by free drinking of N-methyl-N'-nitro-N-nitroso-guanidine solution (100 μg/mL) and irregular diet. Read More

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http://dx.doi.org/10.13702/j.1000-0607.190189DOI Listing

Contrasting serum biomarker profiles in two Colombian populations with different risks for progression of premalignant gastric lesions during chronic Helicobacter pylori infection.

Cancer Epidemiol 2020 May 21;67:101726. Epub 2020 May 21.

Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:

Background: Colombians in coastal Tumaco have a lower incidence of Helicobacter pylori-associated gastric cancer compared to individuals from Tuquerres in the high Andes. This is despite nearly universal prevalence of H. pylori infection and chronic gastritis. Read More

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http://dx.doi.org/10.1016/j.canep.2020.101726DOI Listing