10,436 results match your criteria Gastritis Chronic


How did the ancient bacterium, , cause an epidemic of chronic duodenal ulceration?

JGH Open 2021 Jun 18;5(6):636-642. Epub 2021 May 18.

Faculty of Health and Medical Sciences University of Adelaide Adelaide South Australia Australia.

The association of with chronic duodenal ulceration was a seminal observation in the short history of gastroenterology. However, is now known to be an ancient bacterium, whereas there is persuasive evidence that the epidemic of duodenal ulceration began in the second half of the 19th century and continued into the second half of the 20th century. Possible explanations for the epidemic include genomic changes in the organism and environmental or other influences on the human host. Read More

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Post-transplant relapse of therapy-related MDS as gastric myeloid sarcoma: Case report and review of literature.

Leuk Res Rep 2021 14;15:100244. Epub 2021 May 14.

Department of Hematopathology and Lab Medicine, Moffitt Cancer Center, Tampa, FL, USA.

Introduction: Myelodysplastic syndrome (MDS) are hematologic neoplasms characterized by morphologic dysplasia and ineffective hematopoiesis in the bone marrow. The only potentially curative therapy is stem cell transplant. However, relapse remains a major challenge and is seen in about 25-40% of cases. Read More

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Prevalence of infection and the incidence of the associated malignant and peptic ulcer disease (PUD) at Nelson Mandela Academic Hospital: a retrospective analysis.

Authors:
Stephen Z Molaoa

J Drug Assess 2021 Feb 8;10(1):57-61. Epub 2021 Feb 8.

Walter Sisulu University and Nelson Mandela Academic Hospital, Department of Surgery, and Department of Health Studies, University of South Africa, Mthatha, South Africa.

Background: infection is associated with both benign and malignant gastrointestinal diseases. However, no studies have been conducted locally describing the prevalence of and its associated GIT diseases. The objectives of this study are to determine the prevalence of , and the incidence of PUD and gastric malignancies among patients who are infected with or who have the stigmata of previous exposure to . Read More

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February 2021

A case of lymphocytic esophagitis in a woman with multiple allergies.

Allergy Asthma Clin Immunol 2021 Jun 7;17(1):56. Epub 2021 Jun 7.

Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.

Background: Lymphocytic esophagitis is a newly recognized entity of unknown origin. Dysphagia is defined as difficulty swallowing and represents a common symptom in the general population with a prevalence of approximately 20%. Chronic inflammation of the esophageal wall may manifest itself clinically and endoscopically, mimicking inflammation of another origin. Read More

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Pathological lesions of the digestive tract in free-ranging mountain gorillas (Gorilla beringei beringei).

Am J Primatol 2021 Jun 7:e23290. Epub 2021 Jun 7.

Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

The finding of parasites and bacterial pathogens in mountain gorilla feces and oral lesions in gorilla skeletal remains has not been linked to pathological evidence of morbidity or mortality. In the current study, we conducted a retrospective study of digestive tracts including oral cavity, salivary glands, esophagus, stomach, intestines (gastrointestinal tract [GI]), liver, and pancreas of 60 free-ranging mountain gorillas from Uganda, Rwanda, and the Democratic Republic of Congo that died between 1985 and 2007. We reviewed clinical histories and gross pathology reports and examined histological sections. Read More

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Upper Gastrointestinal Disorders in Adult Patients with Intellectual and Developmental Disabilities.

Cureus 2021 Jun 2;13(6):e15384. Epub 2021 Jun 2.

Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

The purpose of this literature review is to address the diagnosis and treatment of upper gastrointestinal (GI) disorders in patients with intellectual and developmental disabilities (IDD). Manifestations of upper GI dysmotility and disorders include dysphagia, pulmonary aspiration, malnutrition, gastroesophageal reflux, and gastritis, all of which can impact a person's quality of life and lead to chronic, life-threatening conditions. This article will explore the existing diagnostic methods and treatments for gastrointestinal disorders as they relate to patients with IDD. Read More

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Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed.

Cureus 2021 May 31;13(5):e15343. Epub 2021 May 31.

Internal Medicine, Wayne State University, Detroit Medical Center (DMC) Sinai Grace Hospital, Detroit, USA.

Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Read More

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Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab.

Clin Gastroenterol Hepatol 2021 Jun 2. Epub 2021 Jun 2.

Baylor College of Medicine, Houston, TX.

Background & Aims: Eosinophilic gastritis (EG) and eosinophilic duodenitis (EoD), characterized by chronic gastrointestinal (GI) symptoms and increased numbers or activation of eosinophils and mast cells in the GI tract, are likely underdiagnosed. We aimed to determine rates of EG and EoD and number of biopsies required to optimize detection using screening data from a randomized trial of lirentelimab (AK002), an antibody against siglec-8 that depletes eosinophils and inhibits mast cells. We also characterized endoscopic features and symptoms of EG and EoD. Read More

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Mucosal microbial microenvironment in early gastric neoplasia and non-neoplastic gastric disease.

J Gastroenterol Hepatol 2021 Jun 5. Epub 2021 Jun 5.

Department of Gastroenterology and Endoscopy Center, The First Hospital of Jilin University, Changchun, China.

Background And Aim: The biological characterization of microbial environment in early gastric cancer (EGC), other than Helicobacter pylori, is limited. This study aimed to explore the microbial microenvironment in chronic gastritis (CG), fundic gland polyps (FGPs), low-grade intraepithelial neoplasia (LGIN) and EGC.

Methods: 16S-rRNA gene sequencing and bioinformatic analysis were performed on 63 individuals with 252 mucosal biopsies or endoscopic submucosal dissection margin samples from endoscopy. Read More

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The TNF-A-857*T Polymorphism is Associated with Gastric Adenocarcinoma Risk in a Costa Rican Population.

Am J Med Sci 2021 Jan 31. Epub 2021 Jan 31.

Institute of Health Research (INISA), University of Costa Rica, Costa Rica; Department of Public Nutrition, School of Nutrition, University of Costa Rica, Costa Rica. Electronic address:

Background: Costa Rica is ranked as one of the countries with highest incidence of gastric cancer worldwide. Previous studies in Costa Rican populations have revealed associations between gastric cancer risk and several cytokine polymorphisms that seem to play a role in the regulation of the expression of these proteins. In this study, we assessed associations of the polymorphisms IL-6-174 G/C, IFNGR1-56 C/T, IL-8-251 T/A and TNF-A (-857 C/T, -308 A/G) with gastric pathologies in a high-risk population of Latin America. Read More

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January 2021

The Effect of Helicobacter pylori Eradication on Gastric Wall Thickness in Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Obes Surg 2021 Jun 1. Epub 2021 Jun 1.

General Surgery Department, Fatih Sultan Mehmet Training and Research Hospital, Hastane Street No: 1/8 Icerenkoy, 34752, Istanbul, Turkey.

Purpose: The most important cause affecting the thickness of the gastric wall other than the tumor is chronic gastritis caused by Helicobacter pylori (Hp), which is most frequently detected in the antrum. This study aims to investigate the effect of bismuth-based treatment (BBT) combined with proton pump inhibitor (PPI) on wall thicknesses measured in the postoperative gastric specimen and early postoperative complications in patients with Hp-positive pre-LSG endoscopic gastric biopsies.

Materials And Methods: The patients who underwent LSG procedure for morbid obesity were divided into three groups as follows: Hp-negative, Hp-positive without eradication treatment, and Hp-positive, and LSG was performed after eradication treatment. Read More

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Oral Microbiota and Salivary Levels of Oral Pathogens in Gastro-Intestinal Diseases: Current Knowledge and Exploratory Study.

Microorganisms 2021 May 14;9(5). Epub 2021 May 14.

Department of Experimental Medicine, University of Campania Luigi Vanvitelli, Via Luigi de Crecchio, 8, 80138 Naples, Italy.

Various bi-directional associations exist between oral health and gastro-intestinal diseases. The oral microbiome plays a role in the gastro-intestinal carcinogenesis and fusobacteria are the most investigated bacteria involved. This paper aims to review the current knowledge and report the preliminary data on salivary levels of , and in subjects with different gastro-intestinal conditions or pathologies, in order to determine any differences. Read More

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Prevalence rates of heathy stomach mucosa, chronic non-atrophic and atrophic gastritis in endoscopic biopsies in adults born in Finland in 1890-1977.

Authors:
Pentti Sipponen

Scand J Gastroenterol 2021 May 30:1-8. Epub 2021 May 30.

Patolab Oy, Espoo, Finland.

Background: infection, chronic gastritis (CG) and atrophic gastritis (AG) are a continuum of consecutive events in the stomach mucosa. We studied the birth cohort and age group-specific prevalence rates of 'healthy' (N) and 'diseased' stomachs with CG or AG in endoscopic biopsies in adult people born in Finland in 1890-1977.

Materials And Methods: Study series consisted of 690 and 1608 adults with a diagnostic gastroscopy in 1972-1997. Read More

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Does Helicobacter pylori infection affect the structure of bacteria in the gastric mucosa and fluid in patients with chronic antral gastritis?

J Gen Appl Microbiol 2021 May 29. Epub 2021 May 29.

Department of Gastroenterology, People's Hospital of Lishui City.

This study aimed to evaluate the composition of the gastric microbiota in the gastric mucosa and gastric fluid of patients with chronic antral gastritis. Specifically, we sought to determine whether Helicobacter pylori (Hp) infection changes the bacterial community in the gastric mucosa or alters the microbiota in the gastric fluid. The bacterial community at another site in the stomach was also investigated. Read More

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[The autopsy of Napoleon Bonaparte: Anatomo-pathological development for the bicentenary of the death of Napoleon I on the island of Saint Helena in 1821].

Ann Pathol 2021 May 19. Epub 2021 May 19.

Sorbonne université, AP-HP, hôpital Saint-Antoine, service d'anatomie et cytologie pathologiques, Paris, France.

Napoleon Bonaparte died on 5 May 1821 on the island of St Helena after almost six years of exile. The next day, Dr Francesco Antommarchi, a Corsican doctor chosen by the Bonaparte family to treat the exiled emperor, performed the autopsy in the presence of sixteen people, including seven British doctors. Two hundred years after the event of 6 May 1821, the cause of Napoleon's death is still a mystery. Read More

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Clinicopathological features and prognosis of developed gastric cancer based on the diagnosis of mucosal atrophy and enlarged folds of stomach by double-contrast upper gastrointestinal barium X-ray radiography.

Clin J Gastroenterol 2021 May 20. Epub 2021 May 20.

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Background: Mucosal atrophy and enlarged folds of stomach by double-contrast upper gastrointestinal barium X-ray radiography (UGI-XR) are two major features of Helicobacter pylori-induced chronic gastritis. These were previously shown to be risk indicators of gastric cancer, but their predictability for clinicopathological characters of developed gastric cancer is unelucidated. In addition, evidence for decreasing the mortality of gastric cancer by appropriate follow-up of UGI screening is needed. Read More

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Pernicious anemia: Pathophysiology and diagnostic difficulties.

J Evid Based Med 2021 May 20;14(2):161-169. Epub 2021 May 20.

Section of Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, USA.

Pernicious anemia (PA) is the most common cause of vitamin B12 (cobalamin) deficiency anemia in the world. It is an autoimmune disease, comprising of salient features of autoimmune chronic atrophic gastritis (CAG) and cobalamin deficiency (CD). Although the anemia was first described as pernicious, it may well be controlled with vitamin B12 replacement. Read More

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Interleukin- 17agene Polymorphism, Serum Level and Its Tissue Expression in Iraqi Patients Gastric Lesions.

Med Arch 2021 Feb;75(1):23-26

Department of Microbiology, College of Medicine, Al-Iraqia University, Baghdad, Iraq.

Background: T-helper 17 plays a novel role in inflammation in gastritis by producing IL-17A, IL-17A gene polymorphisms that might be responsible for disease susceptibility and development of different gastric lesions.

Objective: The aims of study was to determine the association of IL-17A (G197A) genotype and allele frequency with disease phenotype and risk with different gastric lesions.

Methods: Case controlled study involved 30 gastroduodenal ulcer, 30 chronic gastritis and 30 subjects as a control group with negative endoscopic findings. Read More

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February 2021

Autoimmune polyendocrine syndrome type 1: an Italian survey on 158 patients.

J Endocrinol Invest 2021 May 18. Epub 2021 May 18.

FIRS Laboratories RSR Ltd, Cardiff, UK.

Background: Autoimmune Polyglandular Syndrome type 1 (APS-1) is a rare recessive inherited disease, caused by AutoImmune Regulator (AIRE) gene mutations and characterized by three major manifestations: chronic mucocutaneous candidiasis (CMC), chronic hypoparathyroidism (CH) and Addison's disease (AD).

Methods: Autoimmune conditions and associated autoantibodies (Abs) were analyzed in 158 Italian patients (103 females and 55 males; F/M 1.9/1) at the onset and during a follow-up of 23. Read More

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[Clinical observation on wheat grain moxibustion for chronic superficial gastritis of spleen-stomach deficiency and cold].

Zhongguo Zhen Jiu 2021 May;41(5):511-4

Department of TCM, Kongjiang Hospital, Yangpu District of Shanghai, Shanghai 200093, China.

Objective: To compare the clinical effect of wheat grain moxibustion and warming acupuncture on chronic superficial gastritis of spleen-stomach deficiency and cold.

Methods: A total of 200 patients with chronic superficial gastritis of spleen-stomach deficiency and cold were randomly divided into a wheat grain moxibustion group (100 cases, 13 cases dropped off ) and a warming acupuncture group (100 cases, 16 cases dropped off ). The acupoints of Zhongwan (CV 12), Tianshu (ST 25), Qihai (CV 6), Liangqiu (ST 34) and Zusanli (ST 36) were selected in both groups. Read More

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Draft Genome Sequences of 29 Helicobacter pylori Strains Isolated from Colombia.

Microbiol Resour Announc 2021 May 13;10(19). Epub 2021 May 13.

Infectious Diseases Research Group, Microbiology Department, Sciences Faculty, Pontificia Universidad Javeriana, Bogotá, Colombia

Here, we present the draft genome sequences of 29 Colombian strains. These strains were isolated in Bogotá, Colombia, from patients diagnosed with chronic gastritis. The genomic characterization of these strains will provide more information on the genetic composition of strains from Colombia. Read More

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Dual threat of comorbidity of celiac disease and systemic lupus erythematosus.

J Int Med Res 2021 May;49(5):3000605211012258

Department of Gastroenterology, Suzhou Ninth People's Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.

Celiac disease (CD) is a chronic immune-mediated intestinal disease that is characterized by production of autoantibodies directed against the small intestine. The main clinical manifestations of CD are typically defined as those related to indigestion and malabsorption. These manifestations include unexplained diarrhea or constipation, abdominal pain, bloating, weight loss, anemia, failure-to-thrive in children, and decreased bone density. Read More

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Real-time EndoFaster improves detection in chronic active gastritis.

J Clin Pathol 2021 May 11. Epub 2021 May 11.

Gastroenterology and Digestive Endoscopy, Ospedale di Cattinara, Trieste, Italy.

is the most frequent cause of chronic active gastritis (CAG), namely the first step for gastric cancer development. When infection is not detected at histology, another test is advised. EndoFaster is novel device that reveal the presence of by determining ammonium concentration in the gastric juice during endoscopy. Read More

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Prevalence of tumor necrosis factor alpha inducing protein () gene of and its association with upper gastrointestinal diseases in India.

3 Biotech 2021 May 30;11(5):246. Epub 2021 Apr 30.

Centre for Medical Biotechnology, Amity Institute of Biotechnology, Amity University, Noida, UP India.

() is known to cause several gastroduodenal diseases including chronic Gastritis, Peptic Ulcer disease and Gastric Cancer. Virulent genes of like , are known to be responsible for the disease pathogenesis. However, these virulence genes are not always found to be associated with disease outcome in all populations around the world. Read More

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Polymorphism in BACH2 gene is a marker of polyglandular autoimmunity.

Endocrine 2021 May 8. Epub 2021 May 8.

Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.

Purpose: Genetically predisposed individuals may develop several autoimmune diseases-autoimmune polyendocrine syndromes (APS). APS types 2-4, are complex disorders, which combine various organ-specific autoimmune conditions. Recent reports support the considerable role of the BACH2 gene in immune cell differentiation and shifting the T-cell balance towards regulatory T-cells. Read More

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Study on the Mechanism of Lianpu Drink for the Treatment of Chronic Gastritis Based on Network Pharmacology.

Evid Based Complement Alternat Med 2021 17;2021:6693472. Epub 2021 Apr 17.

Clinical College, Hubei University of Chinese Medicine, Wuhan 430000, China.

Chronic gastritis (CG) places a considerable burden on the healthcare system worldwide. Traditional Chinese Medicine (TCM) formulas characterized by multicompounds and multitargets have been acknowledged with striking effects in the treatment of CG in China's history. Nevertheless, their accurate mechanisms of action are still ambiguous. Read More

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A rare case of emphysematous gastritis caused by Lactobacillus fermentum in a patient with diabetes.

Rev Esp Enferm Dig 2021 May 5. Epub 2021 May 5.

Gastroenterología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México.

A 42-year-old man with a history of type 2 diabetes mellitus (complicated by end stage renal disease on peritoneal dialysis) and chronic diarrhea was admitted to the emergency department for having an exacerbation in the number of evacuations. The patient was hypotensive and lethargic. Arterial blood gases were obtained and reported pH 7. Read More

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The Diagnostic Value of Serum Gastrin-17 and Pepsinogen for Gastric Cancer Screening in Eastern China.

Gastroenterol Res Pract 2021 12;2021:6894248. Epub 2021 Apr 12.

Department of Gastroenterology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objective: To evaluate the diagnostic value of gastrin-17 (G-17) and pepsinogen (PG) in gastric cancer (GC) screening in China, especially eastern China, and to determine the best diagnostic combination and threshold (cutoff values) to screen out patients who need gastroscopy.

Methods: The serum concentrations of G-17 and pepsinogen I and II (PGI and PGII) in 834 patients were analyzed, and the PGI/PGII ratio (PGR) was calculated. According to pathological results, patients can be divided into chronic nonatrophic gastritis (NAG)/chronic atrophic gastritis (CAG)/intraepithelial neoplasia (IN)/GC groups. Read More

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Association of Preinjury Medical Diagnoses With Pediatric Persistent Postconcussion Symptoms in Electronic Health Records.

J Head Trauma Rehabil 2021 Apr 21. Epub 2021 Apr 21.

Department of Neurological Surgery (Drs Yengo-Kahn, Bonfield, and Zuckerman), Vanderbilt Sport Concussion Center (Drs Yengo-Kahn, Bonfield, Gifford, Zuckerman, and Dennis and Ms Hibshman), Division of Epidemiology, Department of Medicine (Mr Torstenson), Vanderbilt Epidemiology Center, Institute for Medicine and Public Health (Mr Torstenson), Vanderbilt Genetics Institute (Mr Torstenson and Drs Davis and Dennis), Department of Neurology (Dr Gifford), and Division of Genetic Medicine, Department of Medicine (Drs Davis and Dennis), Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt University School of Medicine, Nashville, Tennessee (Ms Hibshman); British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada (Ms Belikau and Dr Dennis); and Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada (Dr Dennis).

Objective: To identify risk factors and generate hypotheses for pediatric persistent postconcussion symptoms (PPCS).

Setting: A regional healthcare system in the Southeastern United States.

Participants: An electronic health record-based algorithm was developed and validated to identify PPCS cases and controls from an institutional database of more than 2. Read More

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