9,785 results match your criteria Gastritis Chronic


Non-malignant Helicobacter pylori-Associated Diseases.

Adv Exp Med Biol 2019 Apr 24. Epub 2019 Apr 24.

Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany.

Helicobacter pylori infection of the human stomach is associated with chronic gastritis, peptic ulcer disease or gastric carcinoma, and thus a high burden for the public health systems worldwide. Fortunately, only a small subfraction of up to 15-20% of infected individuals will develop serious complications. Unfortunately, it is not always known upfront, who will be affected by serious diesease outcome. Read More

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http://dx.doi.org/10.1007/5584_2019_362DOI Listing

Immunity and Vaccine Development Against Helicobacter pylori.

Adv Exp Med Biol 2019 Apr 24. Epub 2019 Apr 24.

Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.

Helicobacter pylori is a highly-adapted gastrointestinal pathogen of humans and the immunology of this chronic infection is extremely complex. Despite the availability of antibiotic therapy, the global incidence of H. pylori infection remains high, particularly in low to middle-income nations. Read More

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http://link.springer.com/10.1007/5584_2019_370
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http://dx.doi.org/10.1007/5584_2019_370DOI Listing
April 2019
1 Read

Activity and Functional Importance of Helicobacter pylori Virulence Factors.

Adv Exp Med Biol 2019 Apr 24. Epub 2019 Apr 24.

Division of Microbiology, Department of Biosciences, Paris-Lodron University of Salzburg, Salzburg, Austria.

Helicobacter pylori is a very successful Gram-negative pathogen colonizing the stomach of humans worldwide. Infections with this bacterium can generate pathologies ranging from chronic gastritis and peptic ulceration to gastric cancer. The best characterized H. Read More

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http://dx.doi.org/10.1007/5584_2019_358DOI Listing

The Role of Host Genetic Polymorphisms in Helicobacter pylori Mediated Disease Outcome.

Adv Exp Med Biol 2019 Apr 24. Epub 2019 Apr 24.

School of Medicine, University College Dublin, Dublin, Ireland.

The clinical outcome of infection with the chronic gastric pathogen Helicobacter pylori is not the same for all individuals and also differs in different ethnic groups. Infection occurs in early life (<3 years of age), and while all infected persons mount an immune response and develop gastritis, the majority of individuals are asymptomatic. However, up to 10-15% develop duodenal ulceration, up to 1% develop gastric cancer (GC) and up to 0. Read More

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http://dx.doi.org/10.1007/5584_2019_364DOI Listing

Network pharmacology based investigation into the effect and mechanism of Modified Sijunzi Decoction against the subtypes of chronic atrophic gastritis.

Pharmacol Res 2019 Apr 13;144:158-166. Epub 2019 Apr 13.

Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address:

Chronic atrophic gastritis (CAG) is a common digestive disease without specific treatment. According to syndrome differentiation, traditional Chinese medicine (TCM) classified it into different syndromes and has achieved significant therapeutic effects. In this study, immune repertoire sequencing techniques combined with symptom scores, electronic gastroscopy as well as pathologic changes were used to evaluate the effect and the underlying mechanism of Modified Sijunzi Decoction (MSD) in treating CAG. Read More

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http://dx.doi.org/10.1016/j.phrs.2019.04.012DOI Listing
April 2019
1 Read

Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?

Obes Surg 2019 Apr 15. Epub 2019 Apr 15.

Department of Bariatric Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.

Background: Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological changes. Read More

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http://dx.doi.org/10.1007/s11695-019-03801-yDOI Listing
April 2019
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Evaluating the Accuracy of the Endoscopic ABC Classification System in Diagnosing Helicobacter pylori-Infected Gastritis.

Digestion 2019 Apr 12:1-10. Epub 2019 Apr 12.

Department of General Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Aims: Evaluating the accuracy of the modified Endoscopic ABC (Endo ABC) classification with an electronic endoscopy with narrow band imaging without magnification in diagnosing Helicobacter pylori (H. pylori)-infected gastritis.

Methods: A total of 576 patients were enrolled and they underwent modified Endo ABC. Read More

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http://dx.doi.org/10.1159/000498966DOI Listing

Gastric Microbiota in -Negative and -Positive Gastritis Among High Incidence of Gastric Cancer Area.

Cancers (Basel) 2019 Apr 10;11(4). Epub 2019 Apr 10.

Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama-machi, Yufu-City, Oita 879-5593, Japan.

() related chronic gastritis is a well-known major etiological factor for gastric cancer development. However, -negative gastritis (HpN) is not well described. We aimed to examine gastric mucosal microbiota in HpN compared to -positive gastritis (HpP) and -negative non-gastritis group (control). Read More

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http://dx.doi.org/10.3390/cancers11040504DOI Listing
April 2019
1 Read

Correlation among fecal indicator bacteria and physicochemical parameters with the presence of Helicobacter pylori DNA in raw and drinking water from Bogotá, Colombia.

Helicobacter 2019 Apr 4:e12582. Epub 2019 Apr 4.

Science Faculty, Microbiology Department, Pontificia Universidad Javeriana, Bogotá, Colombia.

Background: The quality of raw and drinking water is a matter of considerable concern due to the possibility of fecal contamination. To assess the quality and public health risk of different types of water, the fecal indicator bacteria (FIB) are used. However, some pathogens, such as Helicobacter pylori, may be present in water when FIB cannot be found. Read More

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http://dx.doi.org/10.1111/hel.12582DOI Listing
April 2019
2 Reads

The relationship between gastric microbiota and gastric disease.

Scand J Gastroenterol 2019 Apr 4:1-6. Epub 2019 Apr 4.

a Endoscopy Center, Tianjin Union Medical Center , Tianjin , China.

Traditionally, the stomach was believed to be a sterile organ unsuitable for microbiota growth. However, the discovery of H. pylori subverted this conception. Read More

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http://dx.doi.org/10.1080/00365521.2019.1591499DOI Listing
April 2019
4 Reads

[Effect of moxibustion at "Zusanli"(ST36) on metabolites of gastric tissue in rats with chronic atrophic gastritis based on metabonomics].

Zhen Ci Yan Jiu 2019 Feb;44(2):113-9

College of Acupuncture-moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410208, China.

Objective: To observe the effect of moxibustion at "Zusanli" (ST36) on metabolites of gastric tissue in chronic atrophic gastritis (CAG) rats, so as to explore the correlation between Yangming Meridian and stomach based on metabolomics.

Methods: Fifty-six SD rats were randomly divided into normal, normal + moxibustion, model and model + moxibustion groups (=14 rats/group). The CAG model was established by gavage of N-methyl-N'-nitro-N-nitroso-guanidine (MNNG) solution and irregular diet for 12 weeks. Read More

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http://www.cnki.net/kcms/doi/10.13702/j.1000-0607.180149.htm
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http://dx.doi.org/10.13702/j.1000-0607.180149DOI Listing
February 2019
8 Reads

Clinicopathological features of duodenal bulb biopsies and their relationship with upper gastrointestinal diseases.

Ann Diagn Pathol 2019 Feb 10;40:40-44. Epub 2019 Feb 10.

Department of Gastroenterology, Peking University Third Hospital, 49 Rd. Garden, Haidian District, Beijing, PR China.

Aim: To assess the prevalence of the lesions in duodenal bulb mucosa and the relationship between duodenal lesions and upper gastrointestinal diseases, including helicobacter pylori infection.

Methods: Clinical, endoscopic and pathological data of the cases with duodenal bulb and gastric mucosal biopsy from January 2005 to May 2017 were analyzed retrospectively.

Results: A total of 3540 patients were enrolled. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2019.02.006DOI Listing
February 2019
2 Reads

Sexual intimacy in later life: From the perspectives of older couples in Malaysia.

Geriatr Gerontol Int 2019 Mar 28. Epub 2019 Mar 28.

Institute for Behavioral Research, Kuala Lumpur, Malaysia.

Aim: To identify the determinants of sexual intimacy among married older people in Malaysia.

Methods: A cross-sectional study was carried out among 1294 married Malaysian older couples who were randomly selected from all 14 states in Malaysia. The data were collected by trained enumerators using a set of validated questionnaires consisting of eight sections, namely sociodemographic characteristics, chronic diseases, perceived health status, life satisfaction, body mass index, disability status (World Health Organization Disability Assessment Schedule), social support (Lubben Social Network Scale) and sexual intimacy. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ggi.13648
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http://dx.doi.org/10.1111/ggi.13648DOI Listing
March 2019
2 Reads

The role of high sensitive C-reactive protein and histopathological evaluation in chronic gastritis patients with or without Helicobacter pylori infection.

Acta Cir Bras 2019 Mar 21;34(3):e201900310. Epub 2019 Mar 21.

Assistant Professor, Balikesir Universty, Faculty of Medicine, Department of Pathology, Balikesir, Turkey. Scientific, intellectual, conception and design of the study; acquisition of data; technical procedures; histopathological examinations; manuscript preparation and writing; critical revision.

Purpose: To evaluate serum levels of high-sensitivity C-reactive protein (hs-CRP) in chronic gastritis patients to predict Helicobacter pylori (HP) infection, inflammatory activity, and precancerous lesions.

Methods: A total of 811 patients with upper gastrointestinal symptoms and histopathological diagnosis of chronic gastritis were enrolled in the study. On endoscopy, five gastric biopsies were taken according to Modified Sydney protocol, which were stained with hematoxylin & eosin and Giemsa. Read More

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http://dx.doi.org/10.1590/s0102-865020190030000010DOI Listing
March 2019
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Ethnic Disparities in Gastric Cancer Presentation and Screening Practice in the United States: Analysis of 1997-2010 Surveillance, Epidemiology, and End Results-Medicare Data.

Cancer Epidemiol Biomarkers Prev 2019 Apr 26;28(4):659-665. Epub 2019 Mar 26.

Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.

Background: Chronic infection with () is the strongest risk factor for distal gastric cancer. Although gastric cancer incidence has decreased, variation by race and ethnicity is observed. This study describes gastric cancer presentation and screening services among Medicare patients by race/ethnicity, place of birth, and history of gastric cancer-related conditions. Read More

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0471DOI Listing
April 2019
1 Read

Lipopolysaccharides From Non-Helicobacter pylori Gastric Bacteria Potently Stimulate Interleukin-8 Production in Gastric Epithelial Cells.

Clin Transl Gastroenterol 2019 Mar;10(3):e00024

Division of Gastroenterology, Department of Medicine, School of Medicine, Jichi Medical University, Tochigi, Japan.

Background: Gastric acid secretion is compromised in chronic Helicobacter pylori (H. pylori) infection allowing overgrowth of non-H. pylori gastric bacteria (NHGB) in the stomach. Read More

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http://dx.doi.org/10.14309/ctg.0000000000000024DOI Listing

Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H. Pylori Infection.

Cell Mol Gastroenterol Hepatol 2019 Mar 23. Epub 2019 Mar 23.

Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka, Japan. Electronic address:

Background & Aims: Epithelial cells are joined by tight junctions (TJs) to form a cell sheet. In the stomach, epithelial cell sheet forms an essential barrier against gastric material, including gastric acid. Although the decreased expression of stomach-type claudin-18 (stCldn18), a TJ protein, is generally observed in human gastritis and gastric cancer, its pathological roles are not fully understood. Read More

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http://dx.doi.org/10.1016/j.jcmgh.2019.03.003DOI Listing

Eosinophilic Gastrointestinal Disorders.

Clin Rev Allergy Immunol 2019 Mar 22. Epub 2019 Mar 22.

Feinberg School of Medicine, Northwestern University, 676 N St. Claire St, Suite 1400, Chicago, IL, 60614, USA.

Eosinophilic gastrointestinal disorders (EGID) are a group of disorders characterized by pathologic eosinophilic infiltration of the esophagus, stomach, small intestine, or colon leading to organ dysfunction and clinical symptoms (J Pediatr Gastroenterol Nutr; Spergel et al., 52: 300-306, 2011). These disorders include eosinophilic esophagitis (EoE), eosinophilic gastritis (EG), eosinophilic gastroenteritis (EGE), eosinophilic enteritis (EE), and eosinophilic colitis (EC). Read More

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http://dx.doi.org/10.1007/s12016-019-08732-1DOI Listing
March 2019
1 Read

Crohn's disease of esophagus, stomach and duodenum.

World J Gastrointest Pharmacol Ther 2019 Mar;10(2):35-49

Programa de Pós graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador 40110-060, Bahia, Brazil.

Crohn's disease with involvement of the esophagus, stomach and duodenum has a prevalence of 0.5% to 4% in symptomatic adult patients, but some studies have shown that these results may be underestimated, since upper gastrointestinal endoscopy is not performed routinely in the initial evaluation of the disease in adult patients, as it is in the pediatric population. In general, involvement of the upper gastrointestinal tract in Crohn's disease occurs concomitantly with involvement of the lower gastrointestinal tract. Read More

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http://dx.doi.org/10.4292/wjgpt.v10.i2.35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422852PMC
March 2019
5 Reads

Three case reports of collagenous gastritis in children: Lessons for an endoscopic and histologic approach to mucosal nodularity of the stomach.

Medicine (Baltimore) 2019 Mar;98(11):e14870

Department of Pediatrics, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.

Rationale: Collagenous gastritis (CG) is a rare form of chronic gastritis defined histologically by a thickened subepithelial collageneous band in the lamina propria. However, the clinical features and endoscopic findings of CG have not been clearly established in the pediatric population.

Presenting Concerns: We report the cases of 3 children who presented with intractable anemia and minimal or no gastrointestinal (GI) symptoms and were followed up without definitive diagnosis determination even through diagnostic endoscopic evaluations. Read More

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http://dx.doi.org/10.1097/MD.0000000000014870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426568PMC
March 2019
7 Reads
5.723 Impact Factor

How dyspepsia led to the diagnosis of Morbus Crohn.

Acta Clin Belg 2019 Mar 18:1-3. Epub 2019 Mar 18.

b Department of Gastroenterology , University hospital Gasthuisberg , Leuven , Belgium.

Background: It is well known that Crohn's disease can involve the stomach. However, most often this upper gastrointestinal tract involvement is asymptomatic. Typically, there is involvement of the small intestine with the typical associated symptoms of Crohn's disease: abdominal cramps, diarrhoea and weight loss. Read More

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http://dx.doi.org/10.1080/17843286.2019.1590497DOI Listing
March 2019
1 Read

Evaluation of emotional, behavioral problems and family functioning in adolescents with chronic gastritis.

Arch Argent Pediatr 2019 Apr;117(2):e110-e114

Departamento de Gastroenterología Pediátrica, Facultad de Medicina de la İzmir Kâtip Çelebi Üniversitesi, Esmirna, Turkey.

Objectives: The aim of the present study was to investigate psychiatric symptoms in adolescents diagnosed as having chronic gastritis, and to evaluate family functioning.

Methods: The population consisted of adolescents who were diagnosed endoscopically and histopathologically as having chronic gastritis without additional chronic disease. The anxiety levels, depression levels, and emotional and behavioral symptoms of the adolescents were measured using the Screen for Child Anxiety Related Emotional Disorders (SCARED), Beck Depression Inventory (BDI), and Strengths and Difficulties Questionnaire (SDQ). Read More

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http://dx.doi.org/10.5546/aap.2019.eng.e110DOI Listing
April 2019
2 Reads

[Effect of modified Zhengqi Powder in treating chronic gastritis and on patients' life quality and inflammatory factors].

Zhongguo Zhong Yao Za Zhi 2019 Jan;44(1):181-185

Beijing Anzhen Hospital Affiliated to Capital Medical University Beijing 100029,China.

Chronic gastritis is a kind of chronic gastric mucosal inflammation caused by many factors.Intestinal metaplasia refers to the transformation of gastric mucosal epithelial cells into small/large intestinal mucosal epithelium containing Panette or goblet cells.Chronic gastritis has the highest incidence among stomach diseases,while intestinal metaplasia is the serious manifestation of chronic gastritis. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.2019.0004DOI Listing
January 2019

Diagnostic value of apolipoprotein C-I, transthyretin and apolipoprotein C-III in gastric cancer.

Oncol Lett 2019 Mar 22;17(3):3227-3232. Epub 2019 Jan 22.

Department of Gastrointestinal Surgery, The First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.

Diagnostic value of apolipoprotein C-I (ApoC-I), transthyretin (TTR) and ApoC-III in gastric cancer were evaluated. Retrospective analysis methods were used to collect 60 patients with gastric cancer first diagnosed in The First Affiliated Hospital of Jiaxing University. There were 60 patients with chronic atrophic gastritis in the benign lesion group and 60 healthy individuals in the control group. Read More

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http://dx.doi.org/10.3892/ol.2019.9957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396204PMC
March 2019
5 Reads

[Helicobacter pylori, nodular gastritis and premalignant stomach lesions: a case-control study].

Rev Gastroenterol Peru 2018 Oct-Dec;38(4):349-355

Unidad de Gastroenterología, Universidad Nacional de Colombia, Hospital Universitario Nacional. Bogotá, Colombia.

Introduction: Nodular gastritis (GN) is a type of gastritis strongly related to Helicobacter pylori and may be a risk factor for gastric cancer. It is a highly prevalent pathology in children infected with H. pylori. Read More

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Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins.

Mucosal Immunol 2019 05 7;12(3):784-794. Epub 2019 Mar 7.

Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, 41390, Sweden.

Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. H. suis colonizes the gastric mucosa of 60-95% of pigs at slaughter age, and is associated with chronic gastritis, decreased weight gain, and ulcers. Read More

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http://dx.doi.org/10.1038/s41385-019-0154-4DOI Listing
May 2019
2 Reads

Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019.

Endoscopy 2019 Apr 6;51(4):365-388. Epub 2019 Mar 6.

Gastroenterology Department, Portuguese Oncology Institute of Porto, Portugal.

Patients with chronic atrophic gastritis or intestinal metaplasia (IM) are at risk for gastric adenocarcinoma. This underscores the importance of diagnosis and risk stratification for these patients. High definition endoscopy with chromoendoscopy (CE) is better than high definition white-light endoscopy alone for this purpose. Read More

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http://dx.doi.org/10.1055/a-0859-1883DOI Listing
April 2019
3 Reads

Health Care Utilization and Health Care Expenditure of Nepali Older Adults.

Front Public Health 2019 15;7:24. Epub 2019 Feb 15.

School of Health and Allied Sciences, Pokhara University, Pokhara, Nepal.

Aging is associated with multiple chronic conditions. In older age, health needs and demand for health services utilization increase. There are limited data in Nepal on the health care utilization as well as health care costs among the elderly population. Read More

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http://dx.doi.org/10.3389/fpubh.2019.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384236PMC
February 2019

Role of Probiotics in Prophylaxis of Helicobacter Pylori Infection.

Curr Pharm Biotechnol 2019 Feb 27. Epub 2019 Feb 27.

Department of Biotechnology, Jaypee Institute of Information Technology, Sector - 62, Noida, U.P., . India.

Helicobacter pylori, a pathogenic bacterium, has been known to be the root cause of numerous gastrointestinal disorders. In patients showing symptoms of its infection, antibiotic therapy is a likely treatment. However, the high cost of antibiotic therapy, associated antibiotic resistance along with other adverse effects has led to the use of probiotics for Helicobacter pylori treatment. Read More

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http://dx.doi.org/10.2174/1389201020666190227203107DOI Listing
February 2019

Eradication of Helicobacter pylori in a Living Donor Liver Transplant Recipient With Immunosuppressive Therapy of Cyclosporine A: A Case Report.

Transplant Proc 2019 Apr 9;51(3):1006-1007. Epub 2019 Jan 9.

Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

A 54-year-old woman underwent living donor liver transplantation (LDLT) for primary biliary cholangitis (PBC) three years earlier. She took cyclosporine A (CyA) 150 mg/day as immunosuppression for prevention of rejection and PBC recurrence. Routine upper gastrointestinal endoscopy showed chronic atrophic gastritis and hyperplastic polyp, and rapid urease test was positive. Read More

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http://dx.doi.org/10.1016/j.transproceed.2019.01.028DOI Listing
April 2019
1 Read

Association of increased B7 protein expression by infiltrating immune cells with progression of gastric carcinogenesis.

Medicine (Baltimore) 2019 Feb;98(8):e14663

Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University Jiangsu Key Laboratory of Clinical Immunology, Soochow University.

B7 negative costimulatory molecules are a group of molecules associated with the occurrence, development, and therapy of cancers. Here, we aimed to determine the clinical significance of PD-L1, B7-H3, and B7-H4 and their expression in CD8 and CD68 positive cells at different stages of gastric carcinogenesis.We detected PD-L1, B7-H3, B7-H4, CD8, and CD68 expression in samples by immunohistochemical staining of 62 chronic superficial gastritis (CSG) samples, 72 chronic atrophic gastritis (CAG) samples, 68 low-grade intraepithelial neoplasia (LIN) samples, 65 high-grade intraepithelial neoplasia (HIN) samples obtained from gastroscopic biopsies and 50 gastric adenocarcinoma (GA) samples obtained from surgical resections. Read More

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http://dx.doi.org/10.1097/MD.0000000000014663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407991PMC
February 2019
4 Reads

CagL polymorphisms D58/K59 are predominant in strains isolated from Mexican patients with chronic gastritis.

Gut Pathog 2019 13;11. Epub 2019 Feb 13.

4Laboratorio de Investigación Clínica, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Av. Lázaro Cárdenas s/n C.U. Sur., C.P. 39090 Chilpancingo, Guerrero Mexico.

Background: is a Gram-negative bacterium that colonizes the gastric mucosa in humans. One of the main virulence factors of is the pathogenicity island (PAI), which encodes a type 4-secretion system (T4SS) and the cytotoxin CagA. Translocation of CagA through the T4SS triggers host-signaling pathways. Read More

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http://dx.doi.org/10.1186/s13099-019-0286-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373039PMC
February 2019
2 Reads

Can neopterin be a useful immune biomarker for differentiating gastric intestinal metaplasia and gastric atrophy from non-atrophic non-metaplastic chronic gastritis?

Gastroenterol Hepatol 2019 Feb 19. Epub 2019 Feb 19.

Usak University, Faculty of Medicine, Medical Oncology Department, Turkey.

Introduction: Helicobacter pylori (H. pylori) is closely related to pre-neoplastic lesions such as gastric atrophy (GA), gastric intestinal metaplasia (GIM) and eventually gastric cancer (GC). The diagnosis of GIM and GA is usually based on endoscopic and histopathological features. Read More

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http://dx.doi.org/10.1016/j.gastrohep.2019.01.005DOI Listing
February 2019
3 Reads

Characterization of digestive disorders of patients with chronic Chagas disease in Cochabamba, Bolivia.

Heliyon 2019 Feb 7;5(2):e01206. Epub 2019 Feb 7.

Fundación CEADES, Cochabamba, Bolivia.

Background: Chagas disease (CD) is endemic in Latin America and particularly common in Bolivia, but there is little information on the characteristics of chronic digestive involvement.

Objectives: To determine the prevalence and characterize digestive manifestations in chronic CD patients in Cochabamba, Bolivia.

Methods: Eighty-five -seropositive individuals with or without digestive symptoms (G1 group), and fifteen -seronegative patients with similar digestive symptoms to those seen in CD (G2 group) were included in the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24058440183676
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http://dx.doi.org/10.1016/j.heliyon.2019.e01206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369243PMC
February 2019
5 Reads

Eosinophilic Gastrointestinal Diseases in Childhood.

Ann Nutr Metab 2018 19;73 Suppl 4:18-28. Epub 2019 Feb 19.

Division on Gastroenterology, Hepatology and Nutrition, First Department of Pediatrics, University of Athens, Children's Hospital "Agia Sofia", Athens, Greece,

Eosinophilic gastrointestinal diseases (EGIDs) comprise a group of chronic, inflammatory diseases of the gastrointestinal (GI) tract, that are characterized, clinically, by symptoms related to the dysfunction of the involved segment(s) of the GI tract, and histologically, by dense eosinophilic inflammation, in the absence of an identifiable secondary cause. The group of EGIDs comprises eosinophilic esophagitis (EoE), eosinophilic gastritis (EG), eosinophilic gastroenteritis (EGE), and eosinophilic colitis (EC). EoE is the most common and the best described EGID compared to EG, EGE, and EC. Read More

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http://dx.doi.org/10.1159/000493668DOI Listing
February 2019
2 Reads

In Vitro Activity of 3-Bromopyruvate, an Anticancer Compound, Against Antibiotic-Susceptible and Antibiotic-Resistant Strains.

Cancers (Basel) 2019 Feb 15;11(2). Epub 2019 Feb 15.

Department of Microbiology, Faculty of Medicine, Wroclaw Medical University, Wroclaw 50-368, Poland.

is a bacterium capable of inducing chronic active gastritis, which in some people, develops into gastric cancers. One of the substances that may be useful in the eradication of this microorganism is 3-Bromopyruvate (3-BP), an anticancer compound with antimicrobial properties. The aim of this article was to determine the activity of 3-BP against antibiotic-susceptible and antibiotic-resistant strains. Read More

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http://www.mdpi.com/2072-6694/11/2/229
Publisher Site
http://dx.doi.org/10.3390/cancers11020229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406402PMC
February 2019
3 Reads

Circulating CD14CD163CD209 M2-like monocytes are associated with the severity of infection in Helicobacter pylori-positive patients.

Mol Immunol 2019 04 13;108:13-22. Epub 2019 Feb 13.

Genetic Diagnosis Center, The First Hospital of Jilin University, Changchun 130021, China; Key Laboratory of Zoonosis Research, Ministry of Education, The First Hospital, Jilin University, Changchun 130021, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China. Electronic address:

Helicobacter pylori (H. pylori) initiates a robust host immune response and subsequently results in chronic inflammation in the gastric mucosa. This study monitored the circulating monocyte subsets and measured the plasma levels of IL-10 and IL-12 in response to H. Read More

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http://dx.doi.org/10.1016/j.molimm.2019.01.017DOI Listing
April 2019
6 Reads

Pathologic findings of the removed stomach during sleeve gastrectomy.

Surg Endosc 2019 Feb 15. Epub 2019 Feb 15.

Department of Bariatric Surgery, Orlando Regional Medical Center, Orlando Health, Orlando, FL, USA.

Background: Laparoscopic sleeve gastrectomy (LSG) is the preferred surgical intervention to treat morbid obesity. Despite the rising popularity of LSG, little is known on the histopathologic findings of the resected partial stomach specimens. Our study aims to identify prevalent pathologic findings of the removed stomach and explore the association between patient characteristics and abnormal findings. Read More

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http://dx.doi.org/10.1007/s00464-019-06689-yDOI Listing
February 2019
2 Reads

[Gastric Neuroendocrine Carcinoma(NEC)Treated with CDDP plus CPT-11 Chemotherapy].

Gan To Kagaku Ryoho 2019 Jan;46(1):65-69

Dept. of Digestive Surgery, Saku Central Hospital Advanced Care Center.

A 69-year-old man with chronic gastritis, reflux esophagitis, esophageal hiatal hernia, and history of appendicitis surgery complained of difficulty swallowing. Upper gastrointestinal endoscopy revealed a 10 cm sized Type 3 gastric cancer. Immunostaining was positive for chromogranin A(2+), synaptophysin(3+), CD56(-), and Ki-67>70%. Read More

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January 2019
12 Reads

Notoginsenoside R1 (NGR1) Attenuates Chronic Atrophic Gastritis in Rats.

Med Sci Monit 2019 Feb 13;25:1177-1186. Epub 2019 Feb 13.

External Liaison Office, Second Affiliated Hospital of Nanjing University of Chinese Medicine (Second Hospital of Jiangsu Province), Nanjing, Jiangsu, China (mainland).

BACKGROUND This study investigated the effect and mechanism of notoginsenoside R1 (NGR1) on chronic atrophic gastritis (CAG) in a rat model. MATERIAL AND METHODS To perform our investigation, a rat model of CAG was established, and then rats were treated with various doses of NGR1. After treatment, hematoxylin-eosin (HE) staining was used for histopathological observation and further scoring. Read More

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http://dx.doi.org/10.12659/MSM.911512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381808PMC
February 2019
5 Reads

A High Prevalence of Gastrointestinal Manifestations in Common Variable Immunodeficiency.

Am J Gastroenterol 2019 Apr;114(4):648-655

Department of Gastroenterology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Objectives: Common variable immunodeficiency (CVID) is associated with a spectrum of autoimmune complications. We studied the prevalence of gastrointestinal (GI) manifestations and infections in patients with CVID.

Methods: Complete clinical data of 132 Finnish patients with CVID (106 probable and 26 possible CVID) followed up between 2007 and 2016 were collected to a structured database. Read More

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http://dx.doi.org/10.14309/ajg.0000000000000140DOI Listing
April 2019
3 Reads

Identification of non-invasive biomarkers for chronic atrophic gastritis from serum exosomal microRNAs.

BMC Cancer 2019 Feb 8;19(1):129. Epub 2019 Feb 8.

Guangzhou University of Chinese Medicine, No.12 Jichang Road, Guangzhou, 510405, Guangdong Province, China.

Background: Serum exosomal microRNAs (miRNAs) have been suggested as novel biomarkers for various diseases, especially gastric cancer (GC). But circulating biomarkers for Chronic atrophic gastritis (CAG) which is defined as precancrerous lesions of GC remain largely elusive. To investigate serum exosomal miRNAs that are differently expressed in CAG patients and Chronic nonatrophic gastritis (CNAG) may be helpful for its diagnosis and therapy. Read More

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http://dx.doi.org/10.1186/s12885-019-5328-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368711PMC
February 2019
5 Reads

Helicobacter pylori infection alters gastric and tongue coating microbial communities.

Helicobacter 2019 Apr 7;24(2):e12567. Epub 2019 Feb 7.

The Traditional Chinese Medicine Hospital of Shijiazhuang Affiliated to Hebei University of Chinese Medicine, Shijiazhuang, China.

Objective: Infection with Helicobacter pylori (H pylori), especially cytotoxin-associated gene A-positive (CagA+) strains, has been associated with various gastrointestinal and extragastric diseases. The aim of this study was to characterize H pylori-induced alterations in the gastric and tongue coating microbiota and evaluate their potential impacts on human health.

Design: The gastric mucosa and tongue coating specimens were collected from 80 patients with chronic gastritis, and microbiota profiles were generated by 16S rRNA gene sequencing. Read More

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http://doi.wiley.com/10.1111/hel.12567
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http://dx.doi.org/10.1111/hel.12567DOI Listing
April 2019
16 Reads

Helicobacter pylori infection in children: an overview of diagnostic methods.

Eur J Clin Microbiol Infect Dis 2019 Feb 7. Epub 2019 Feb 7.

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Islamic Republic of Iran.

Children differ from adults regarding Helicobacter pylori (H. pylori) infection in many terms. H. Read More

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http://link.springer.com/10.1007/s10096-019-03502-5
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http://dx.doi.org/10.1007/s10096-019-03502-5DOI Listing
February 2019
18 Reads

Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens.

Ter Arkh 2018 Nov;90(11):79-89

N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.

Borreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Read More

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http://dx.doi.org/10.26442/terarkh2018901179-89DOI Listing
November 2018
2 Reads

Comorbid for gastroduodenal ulcers in the aspect of calcium imbalance and blockers of slow calcium channels in their treatment.

Authors:
L A Fomina

Ter Arkh 2018 Feb;90(2):28-34

Tver State Medical University, Ministry of Health of Russia, Tver, Russia.

Aim: Find out the calcium content of the blood reflecting its balance and functional status the calcium regulatory system when it is comorbid for gastroduodenal ulcers (GDU), developed on the background of chronic erosive gastritis (CEG), chronic erosive duodenitis (CED), arterial hypertension (AH) and osteo-articular pathology with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), and the impact of his changes on the activity ulzerogennogo process, the state of regional microcirculation and the functions of the stomach. To determine the pathogenetic justification for and effectiveness of blockers of slow calcium channels (BSCaC) in complex treatment.

Materials And Methods: Examined 132 patients with GDU. Read More

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http://dx.doi.org/10.26442/terarkh201890228-34DOI Listing
February 2018
3 Reads

A human mode of intestinal type gastric carcinoma.

Authors:
Shaoqing Lai

Med Hypotheses 2019 Feb 14;123:27-29. Epub 2018 Dec 14.

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:

Gastric cancer is a malignant tumor originating from the gastric mucosa epithelium. Intestinal type gastric cancer is frequently taken on elderly men, and there are many high incidence areas around the world. Intestinal type gastric cancer often is accompanied by gastric mucosal atrophy, intestinal metaplasia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03069877183121
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http://dx.doi.org/10.1016/j.mehy.2018.12.009DOI Listing
February 2019
16 Reads

NKX6.3 protects against gastric mucosal atrophy by downregulating β-amyloid production.

World J Gastroenterol 2019 Jan;25(3):330-345

Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul 06591, South Korea.

Background: Atrophic gastritis is characterized by loss of appropriate glands and reduction in gastric secretory function due to chronic inflammatory processes in gastric mucosa. Moreover, atrophic gastritis is considered as a precancerous condition of gastric cancer. However, little is known about the molecular mechanism underlying gastric mucosal atrophy and its contribution to gastric carcinogenesis. Read More

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http://dx.doi.org/10.3748/wjg.v25.i3.330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343100PMC
January 2019
3 Reads

Helicobacter pylori vacA, cagA and iceA genotypes in dyspeptic patients from southwestern region, Saudi Arabia: distribution and association with clinical outcomes and histopathological changes.

BMC Gastroenterol 2019 Jan 25;19(1):16. Epub 2019 Jan 25.

Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.

Background: The aim of this study was to identify the common H. pylori virulence genes among dyspeptic Southwestern Saudi patients and their association with clinical outcomes and histopathological findings to help practitioners and researchers in the region for better management of infections caused by such bacteria.

Methods: Four hundred two gastric biopsy specimens were analyzed using histopathological examination and real time-PCR. Read More

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http://dx.doi.org/10.1186/s12876-019-0934-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346553PMC
January 2019
4 Reads

Diagnostic performance of serum pepsinogen assay for the prediction of atrophic gastritis and gastric neoplasms: Protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2019 Jan;98(4):e14240

Department of Internal Medicine.

Background: Serum pepsinogen assay (sPGA) combining concentration of pepsinogen I (PG I), and the ratio of PG I/II is the noninvasive biomarker for predicting chronic atrophic gastritis (CAG) and neoplasms reflecting mucosal secretory status. Although various cut-off values have been suggested, PG I ≤70 ng/mL and PG I/II ≤3 have been widely accepted. However, previous studies for diagnostic test accuracy presented only pooled outcomes, which cannot discriminate the diagnostic validity of sPGA with cut-off of PG I ≤70 ng/mL and PG I/II ≤3. Read More

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http://dx.doi.org/10.1097/MD.0000000000014240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358409PMC
January 2019
4 Reads
5.723 Impact Factor