1,905 results match your criteria Gastritis Acute


Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in rats.

BMC Pharmacol Toxicol 2019 Feb 15;20(1):13. Epub 2019 Feb 15.

Institute of Biological Science, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia.

Background: Basic function of bromine in body is to activate pepsin production in gastritis with low acidity. The present study encompasses a broad in vivo study to evaluate gastroprotective activity of a novel dibromo substituted Schiff base complex against Sprague Dawley (SD) rats.

Methods: 2, 2'-[1, 2-cyclohexanediylbis (nitriloethylidyne)]bis(4-bromophenol) (CNBP) is synthesized via a Schiff base reaction, using the related ketone and diamine as the starting materials. Read More

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http://dx.doi.org/10.1186/s40360-019-0292-zDOI Listing
February 2019

Subacute and subchronic oral toxicity assessments of (DC.) Guill. & Perr. root in Wistar rats.

Toxicol Rep 2019 30;6:161-175. Epub 2019 Jan 30.

Department of Pharmacology, Therapeutics & Toxicology, College of Medicine, University of Lagos, P.M.B, 12003, Idi-Araba, Lagos, Nigeria.

Recent adverse herb reactions have stimulated interest documenting the safety profile of medicinal agents. Thus, subacute and subchronic oral toxicity of the hydroethanolic extract of root (HEASR) in Wistar rats was investigated. In the 28 and 90-day subacute and subchronic toxicity tests, sixty-four rats (n = male: female = 1:1 = 32) were divided into four of eight/group and ninety-six (n = male: female = 1:1 = 48) into twelve/group respectively. Read More

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http://dx.doi.org/10.1016/j.toxrep.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360914PMC
January 2019

Attitude and knowledge of Saudi community pharmacists towards use of proton pump inhibitors.

Saudi Pharm J 2019 Feb 7;27(2):225-228. Epub 2018 Nov 7.

Department of Clinical Pharmacy, King Saud University, Saudi Arabia.

Introduction: Proton pump inhibitors (PPIs) effectively suppress acid secretion and play an important role in peptic ulcer disease and gastroesophageal reflux disease There is a real concern about the overutilization of PPIs, which will lead to significant high cost and undesirable outcomes Despite that most of PPIs are classified as prescribed medications, yet most of their users take them without prescription in Saudi Arabia. Therefore, it was important to understand community pharmacists practice in dealing with PPIs and to evaluate their despising pattern of these medications.

Method: A cross-sectional survey-based study that was carried out between September and December 2017. Read More

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http://dx.doi.org/10.1016/j.jsps.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362272PMC
February 2019

Efficiency of local therapy with the use of a new preparation for oral care at periodontitis in the course of hyperpeptic gastritis after tobacco smoke intoxication.

Wiad Lek 2018 ;71(9):1695-1700

Ukrainian Medical Stomatological Academy, Poltava, Ukraine.

Objective: Introduction: Periodontal diseases, arising against a background of stomach pathology at tobacco addiction remain an acute problem of modern dentistry. The aim of the work is an experimental study of efficiency of application of the new preparation for oral care during treatment of periodontitis simulated against a background of hyperpeptic gastritis under conditions of intoxication by tobacco smoke.

Patients And Methods: Materials and methods: At the first stage all experimental animals were divided into 4 groups: І - intact, II - with simulated periodontitis, III - with simulated periodontitis against a background of simulated hyperpeptic gastritis, IV - with simulated periodontitis against a background of hyperpeptic gastritis under conditions of tobacco smoking. Read More

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January 2018
1 Read

Case of thrombosis of the portal vein and its branches in a patient seropositive for Borrelia antigens.

Ter Arkh 2018 Nov;90(11):79-89

N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.

Borreliosis after sucking ticks is an acute problem in the world. People do not go to doctors after that often, which leads to the development of various complications. Thrombosis of veins of various localization can be one of them. Read More

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http://dx.doi.org/10.26442/terarkh2018901179-89DOI Listing
November 2018
1 Read

Efficacy and Safety of Combination of NSAIDs and Muscle Relaxants in the Management of Acute Low Back Pain.

Pain Ther 2019 Jan 16. Epub 2019 Jan 16.

Global Medical Affairs, Dr Reddy's Laboratories Ltd, 8-2-337, Road No 3, Banjara Hills, Hyderabad, 500034, India.

Introduction: Low back pain is a common problem worldwide causing deterioration of health and quality of life. Low back pain is often associated with muscle spasm. We investigated the combined effect of muscle relaxants and pain killers for low back pain. Read More

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http://dx.doi.org/10.1007/s40122-019-0112-6DOI Listing
January 2019
5 Reads

Emergency Presentation of Gastric Ectopic Pancreas.

Cureus 2018 Nov 8;10(11):e3565. Epub 2018 Nov 8.

Surgery, Papa Giovanni Xxiii Hospital, Bergamo, ITA.

Ectopic pancreas is a rare embryological abnormality apparently not in association with others. Stomach and duodenum are the most common organs involved. Symptoms are nonspecific. Read More

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https://www.cureus.com/articles/14601-emergency-presentation
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http://dx.doi.org/10.7759/cureus.3565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325026PMC
November 2018
6 Reads

Unexplained Portal Gas in a Patient with an Esophageal Ulcer.

Case Rep Gastrointest Med 2018 10;2018:2496193. Epub 2018 Dec 10.

Sinai Hospital, Baltimore, Maryland, USA.

Emphysematous gastritis is the infection of gastric mucosa by gas producing microorganisms. It is a rare infection with less than 100 cases reported in the literature. The association of portal venous gas along with emphysematous gastritis is a rare entity. Read More

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http://dx.doi.org/10.1155/2018/2496193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311260PMC
December 2018
2 Reads

Cochlospermum regium (Mart. ex Schrank) Pilg.: Evaluation of chemical profile, gastroprotective activity and mechanism of action of hydroethanolic extract of its xylopodium in acute and chronic experimental models.

J Ethnopharmacol 2019 Apr 3;233:101-114. Epub 2019 Jan 3.

Área de Farmacologia, Departamento de Ciências Básicas em Saúde, Faculdade de Medicina, Universidade Federal de Mato Grosso (UFMT), Cuiabá, Brazil. Electronic address:

Ethnopharmacological Relevance: Cochlospermum regium (Bixaceae) is a native shrub of Brazil and its xylopodium (infusion/decoction) is being used for the treatment of gastritis, ulcers, arthritis, intestinal infections, gynaecological infections, skin diseases, among others. The aim of the present study was to evaluate the gastroprotective/antiulcer activity and the mechanism of action of hydroethanolic extract of C. regium xylopodium (HECr), using in vitro and in vivo models. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183292
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http://dx.doi.org/10.1016/j.jep.2019.01.002DOI Listing
April 2019
6 Reads

Effect of patchouli alcohol on Helicobacter pylori-induced neutrophil recruitment and activation.

Int Immunopharmacol 2019 Mar 29;68:7-16. Epub 2018 Dec 29.

The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. Electronic address:

Neutrophil infiltration typically occurs in Helicobacter pylori (H. pylori)-induced acute gastritis; however, this immune response fails to eradicate H. pylori in vivo. Read More

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http://dx.doi.org/10.1016/j.intimp.2018.12.044DOI Listing
March 2019
3 Reads
2.472 Impact Factor

Abnormalities in acute salivary biochemical characteristic responses to gustatory stimulation with citric acid in chronic non-atrophic gastritis.

J Gastroenterol Hepatol 2018 Dec 29. Epub 2018 Dec 29.

Pi-Wei Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.

Background And Aim: Salivary characteristics are altered in gastrointestinal diseases and related to oral taste disorder. However, specific salivary biochemical characteristics and their relationships with oral taste disturbances in chronic non-atrophy gastritis (CNAG) remain uncertain.

Methods: Seventy patients with CNAG and 70 subjects in healthy control group (HCG) were enrolled in our study. Read More

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http://dx.doi.org/10.1111/jgh.14587DOI Listing
December 2018
13 Reads

Ibuprofen, a Potential Cause of Acute Hemorrhagic Gastritis in Children - A Case Report.

J Crit Care Med (Targu Mures) 2018 Oct 1;4(4):143-146. Epub 2018 Oct 1.

University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureş, Romania.

Introduction: Upper gastrointestinal bleeding is an uncommon but possible life-threatening entity in children, frequently caused by erosive gastritis. Non-steroidal anti-inflammatory drugs are one of the most common class of drugs which can cause gastrointestinal complications, including hemorrhagic gastritis.

Case Report: The case of a 6-year-old male, admitted for hematemesis, abdominal pain and loss of appetite. Read More

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http://content.sciendo.com/view/journals/jccm/4/4/article-p1
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http://dx.doi.org/10.2478/jccm-2018-0022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296277PMC
October 2018
11 Reads

Reduced Prevalence of Alcoholic Gastritis in Hospitalized Individuals Who Consume Cannabis.

Alcohol Clin Exp Res 2019 Feb 24;43(2):270-276. Epub 2018 Dec 24.

Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.

Background: Alcoholic gastritis, a superficial erosive disease of the stomach, is a common manifestation of risky alcohol use. In contrast, cannabis which is frequently co-used with alcohol suppresses gastric acidity and might counteract the deleterious effect of alcohol on the gastric mucosa. However, no clinical study has examined the impact of cannabis use on the development of alcoholic gastritis among risky alcohol users. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/acer.13930
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http://dx.doi.org/10.1111/acer.13930DOI Listing
February 2019
13 Reads

Patient Characteristics from an Emergency Care Center in Rural Western Kenya.

J Emerg Med 2019 Jan 4;56(1):80-86. Epub 2018 Dec 4.

Division of Global Health and Human Rights, Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts; African Institute for Health Transformation at Sagam Community Hospital, Luanda, Kenya; Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

Background: Emergency care is a neglected area of focus in many low- and middle-income countries. There is a paucity of research on types and frequencies of acute illnesses and injuries in low-resource settings.

Objective: The primary objective of this study was to describe the demographic characteristics and emergency conditions of patients that presented to a new emergency care center (ECC) at Sagam Community Hospital in Luanda, Kenya. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.10.019DOI Listing
January 2019
1 Read

Emergency room visits and admission rates of children with neuromuscular disorders: A 10-year experience in a medical center in Taiwan.

Pediatr Neonatol 2018 Oct 2. Epub 2018 Oct 2.

Division of Pediatric Emergency, Department of Emergency, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Ph.D. Program in Translational Medicine, Graduate Institute of Clinical Medicine, 18 Kaohsiung Medical University and Academia Sinica, Taiwan; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

Background: No previous studies have explored emergency medical care for children with chronic neuromuscular disorders (NMDs). We aimed to determine the major reasons for the emergency room (ER) readmission of pediatric patients with NMDs and suggest changes to the care plan to decrease readmissions.

Methods: Children with chronic NMDs (aged <18 years) who visited a medical center-based ER between January 2005 and January 2015 were included. Read More

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http://dx.doi.org/10.1016/j.pedneo.2018.09.008DOI Listing
October 2018
4 Reads
0.880 Impact Factor

Acute gastritis caused by concurrent infection with Epstein-Barr virus and cytomegalovirus in an immunocompetent adult.

Clin J Gastroenterol 2018 Nov 16. Epub 2018 Nov 16.

Department of Diagnostic Pathology, Anjo Kosei Hospital, 28 Higashi-hirokute, Anjo-cho, Anjo, Aichi, 446-8602, Japan.

Herein, we describe an extremely rare case of gastritis due to concurrent infection with Epstein-Barr virus (EBV) and cytomegalovirus (CMV) occurring in an immunocompetent adult. The patient was a 35-year-old man who presented with slight fever, nausea, anorexia, weight loss for 3 weeks, mild transaminitis, and leukocytosis with atypical lymphocytes in peripheral blood. The clinical presentation and elevated IgM titers to both EBV-VCA and CMV strongly suggested infectious mononucleosis syndrome caused by co-infection with EBV and CMV. Read More

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http://link.springer.com/10.1007/s12328-018-0924-7
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http://dx.doi.org/10.1007/s12328-018-0924-7DOI Listing
November 2018
15 Reads

Pneumatosis intestinalis a trap for the unwary: Case series and literature review.

Int J Surg Case Rep 2018 2;53:214-217. Epub 2018 Nov 2.

Royal Alexandra Hospital, Corsebar Rd, Paisely, PA2 9PN, Scotland, UK. Electronic address:

Introduction: Pneumatosis Intestinalis (PI) can present with a broad range of presentations from chronic and non-specific to acute and life threatening. It is paradoxically one of the few conditions where a pneumoperitoneum found in the diagnostic workup is not necessarily an indication for laparotomy.

Presentation Of Cases: The first case is of a 75 year old gentlemen who attended the emergency department after several weeks of worsening abdominal pain and weight loss. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183050
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http://dx.doi.org/10.1016/j.ijscr.2018.10.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232619PMC
November 2018
10 Reads

Streptococcal toxic shock syndrome with primary group A streptococcus peritonitis in a healthy female.

J Community Hosp Intern Med Perspect 2018 15;8(5):317-320. Epub 2018 Oct 15.

Internal Medicine Department, McLaren-Flint/Michigan State University, Flint, MI, USA.

A 47-year-old female with a history of chronic alcoholism presented with nausea, vomiting and mild epigastric tenderness. She reported subjective fever, abdominal fullness and loose, watery stools and had stable vitals on arrival. Examination was positive for mild epigastric tenderness with hepatic enlargement. Read More

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https://www.tandfonline.com/doi/full/10.1080/20009666.2018.1
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http://dx.doi.org/10.1080/20009666.2018.1527669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197016PMC
October 2018
17 Reads

An atypical presentation of an acute gastric Helicobacter felis infection.

Acta Gastroenterol Belg 2018 Jul-Sep;81(3):436-438

Department of Gastroenterology, University Hospital Leuven, Belgium.

Helicobacter pylori is a Gram negative bacterium that has been associated with a wide variety of gastric pathologies in humans. Besides this well studied gastric pathogen, other Helicobacter spp. have been detected in a minority of patients with gastric disease. Read More

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October 2018
2 Reads

Eculizumab and thrombotic microangiopathy after hematopoietic stem cell transplantation: A report on its efficacy and safety in two pediatric patients.

Arch Pediatr 2018 Nov 16;25(8):485-488. Epub 2018 Oct 16.

Centre de référence des maladies rénales rares, hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, 59, boulevard Pinel 69677 Bron cedex, France. Electronic address:

Background: Thrombotic microangiopathy (TMA) is a severe complication after hematopoietic stem cell transplantation (HSCT), with the reported mortality rate in such cases usually reaching 90%.

Cases: We report on two pediatric cases of patients successfully treated by eculizumab for severe HSCT-TMA, occurring in two girls (8.4 and 3. Read More

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http://dx.doi.org/10.1016/j.arcped.2018.09.011DOI Listing
November 2018
2 Reads

Successful Antimicrobial Treatment of Phlegmonous Gastritis: A Case Report and Literature Review.

Case Rep Hematol 2018 16;2018:8274732. Epub 2018 Sep 16.

Department of Hematology and Oncology, Mayo Clinic, Jacksonville, FL, USA.

Phlegmonous gastritis is an uncommon acute bacterial infection of the stomach that carries a fatal prognosis in spite of the advent of antibiotics. A high index of suspicion is required in patients with risk factors. An immunocompromised state is identified as one of the most important risk factors. Read More

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https://www.hindawi.com/journals/crihem/2018/8274732/
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http://dx.doi.org/10.1155/2018/8274732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164362PMC
September 2018
4 Reads

Thoracic and abdominal pain in a 28-year-old woman with a failing kidney transplant.

Frontline Gastroenterol 2018 Oct 3;9(4):323-324. Epub 2018 Jul 3.

Gastroenterology and Hepatology, Jeroen Bosch Ziekenhuis, Den Bosch, Noord-Brabant, The Netherlands.

This case report describes a young, immunocompromised patient who presented with thoracic pain. After an extensive workup, she was diagnosed with a varicella zoster virus infection with involvement of the gastric mucosa, pancreas and lungs for which she was treated with acyclovir. Although the viral load decreased significantly, the patient had persistent postherpetic neuralgia and nausea. Read More

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http://dx.doi.org/10.1136/flgastro-2018-101025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145439PMC
October 2018
3 Reads

Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis.

Authors:
Si Ming Man

Nat Rev Gastroenterol Hepatol 2018 Dec;15(12):721-737

Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia.

Inflammasome signalling is an emerging pillar of innate immunity and has a central role in the regulation of gastrointestinal health and disease. Activation of the inflammasome complex mediates both the release of the pro-inflammatory cytokines IL-1β and IL-18 and the execution of a form of inflammatory cell death known as pyroptosis. In most cases, these mediators of inflammation provide protection against bacterial, viral and protozoal infections. Read More

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http://www.nature.com/articles/s41575-018-0054-1
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http://dx.doi.org/10.1038/s41575-018-0054-1DOI Listing
December 2018
31 Reads

4-Hydroxynonenal in Redox Homeostasis of Gastrointestinal Mucosa: Implications for the Stomach in Health and Diseases.

Antioxidants (Basel) 2018 Sep 3;7(9). Epub 2018 Sep 3.

Laboratory for Oxidative Stress (LabOS), Institute "Rudjer Boskovic", HR-10000 Zagreb, Croatia.

Maintenance of integrity and function of the gastric mucosa (GM) requires a high regeneration rate of epithelial cells during the whole life span. The health of the gastric epithelium highly depends on redox homeostasis, antioxidant defense, and activity of detoxifying systems within the cells, as well as robustness of blood supply. Bioactive products of lipid peroxidation, in particular, second messengers of free radicals, the bellwether of which is 4-hydroxynonenal (HNE), are important mediators in physiological adaptive reactions and signaling, but they are also thought to be implicated in the pathogenesis of numerous gastric diseases. Read More

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http://www.mdpi.com/2076-3921/7/9/118
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http://dx.doi.org/10.3390/antiox7090118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162398PMC
September 2018
15 Reads

H. pylori-associated pathologic findings among Alaska native patients.

Int J Circumpolar Health 2018 12;77(1):1510715

a Arctic Investigations Program , DPEI/NCEZID, Centers for Disease Control and Prevention , Anchorage , AK , USA.

Helicobacter pylori infection is common among Alaska native (AN) people, however scant gastric histopathologic data is available for this population. This study aimed to characterise gastric histopathology and H. pylori infection among AN people. Read More

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http://dx.doi.org/10.1080/22423982.2018.1510715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116699PMC
December 2018
19 Reads

Acute gastric necrosis caused by a β-hemolytic streptococcus infection: a case report and review of the literature.

Acta Chir Belg 2018 Aug 24:1-4. Epub 2018 Aug 24.

b Department of Surgery , Universitair Medisch Centrum Utrecht , Utrecht , Netherlands.

Acute necrotizing gastritis, which appears to be a variant of phlegmonous gastritis is the rarest cause of gastric necrosis. We report a case of a 57-year-old female patient with an acute necrotizing gastritis caused by a Group A β-hemolytic streptococcus. The case presented herein is of unusual interest because only a limited number of case reports on this etiology have been published. Read More

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http://dx.doi.org/10.1080/00015458.2018.1500799DOI Listing
August 2018
6 Reads

Sepsis caused by acute phlegmonous gastritis based on a group A .

J Surg Case Rep 2018 Aug 4;2018(8):rjy188. Epub 2018 Aug 4.

Department of Surgery, Amphia Hospital Breda, Breda, the Netherlands.

We present a case of 45-year-old male with acute phlegmonous gastritis (APG) based on a hemolytic group A APG is a rare and often a potentially fatal disease, which is characterized by a severe bacterial infection of the gastric wall. Because APG is a rapidly progressive disease, it comes with high mortality rates. Patients with an early diagnosis may undergo successful treatment and have a survival benefit. Read More

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http://dx.doi.org/10.1093/jscr/rjy188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077785PMC
August 2018
2 Reads

High Incidence of Early Human Herpesvirus-6 Infection in Children Undergoing Haploidentical Manipulated Stem Cell Transplantation for Hematologic Malignancies.

Biol Blood Marrow Transplant 2018 Dec 29;24(12):2549-2557. Epub 2018 Jul 29.

Pediatric Hematology-Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

Human herpesvirus-6 (HHV-6) infection is increasingly recognized among allogeneic hematopoietic stem cell transplantation (HSCT) recipients, with 30% at risk of reactivation in the haploidentical setting. It has been associated with encephalitis, acute graft-versus-host disease, and graft failure. Here we report 2 cohorts of pediatric haploidentical manipulated HSCT in which, despite many differences, HHV-6 reactivation and disease occurred with very high incidence compared with data reported in the literature and represented the main early post-transplant infectious complication compared with other viral, bacterial, or fungal infections. Read More

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http://dx.doi.org/10.1016/j.bbmt.2018.07.033DOI Listing
December 2018
5 Reads
3.404 Impact Factor

An elderly patient's complete response to steroid therapy for collagenous gastritis.

Ther Adv Chronic Dis 2018 Aug 19;9(8):143-146. Epub 2018 Mar 19.

Hofstra Northwell School of Medicine, Manhasset, NY, USA.

An 85-year-old woman presented with 9.1 kg (20 lb) weight loss over 5 months and an acute onset crampy abdominal pain. Examination revealed a diffusely tender abdomen, with gastric wall thickening noted on CT scan. Read More

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http://dx.doi.org/10.1177/2040622318759628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052503PMC
August 2018
32 Reads

Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infection.

Eur J Med Chem 2018 Aug 2;156:126-136. Epub 2018 Jul 2.

National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, 416000, PR China; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, PR China. Electronic address:

A novel series of aniline-containing hydroxamic acids were designed, synthesized and evaluated as anti-virulence agents for the treatment of gastritis and gastric ulcer caused by Helicobacter pylori. In vitro enzyme-based screen together with in vivo assays and structure-activity relationship (SAR) studies led to the discovery of three potent urease inhibitors 3-(3,5-dichlorophenylamino)N-hydroxypropanamide (3a), 3-(2-chlorophenylamino)N-hydroxypropanamide (3d) and 3-(2,4-dichlorophenylamino)N-hydroxypropanamide (3n). Compounds 3a, 3d and 3n showed excellent urease inhibition with IC values 0. Read More

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http://dx.doi.org/10.1016/j.ejmech.2018.06.065DOI Listing
August 2018
13 Reads

A case of Metaplastic atrophic gastritis in immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) syndrome.

BMC Pediatr 2018 06 15;18(1):191. Epub 2018 Jun 15.

Gastroenterology Department, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Background: Autoimmune metaplastic atrophic gastritis is a chronic progressive inflammatory condition. The clinical spectrum includes pernicious anemia, atrophic gastritis, antibodies to parietal cell antigens and intrinsic factor, achlorhydria, hypergastrinemia and carcinoma. It is rare in paediatric cohorts. Read More

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http://dx.doi.org/10.1186/s12887-018-1169-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002972PMC
June 2018
14 Reads

The efficacy and safety of irsogladine maleate in nonsteroidal anti-inflammatory drug or aspirin-induced peptic ulcer and gastritis.

Korean J Intern Med 2018 Jun 1. Epub 2018 Jun 1.

Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea.

Background/aims: Irsogladine maleate, an enhancer of gastric mucosal protective factors, has demonstrated its efficacy for various gastric mucosal injuries. The aim of this study was to evaluate the efficacy and safety of irsogladine for prevention of nonsteroidal anti-inflammatory drugs (NSAIDs) or aspirin-induced peptic ulcer and gastritis.

Methods: In this multicenter, randomized, double-blind, exploratory clinical trial, 100 patients over 50 years of age who needed continuous NSAIDs or aspirin for more than 8 weeks were randomly assigned to either test group (irsogladine maleate 2 mg, twice daily, 39 patients for full analysis) or placebo group (37 patients for full analysis). Read More

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http://dx.doi.org/10.3904/kjim.2017.370DOI Listing
June 2018
7 Reads

Indomethacin-induced gastric damage in rats and the protective effect of donkey milk.

Arch Med Sci 2018 Apr 20;14(3):671-678. Epub 2016 May 20.

Department of Pathology, Medical Faculty, Trakya University, Edirne, Turkey.

Introduction: Indomethacin is an anti-inflammatory drug with clearly known side effects on gastric mucosa. New treatment and side effect prevention methods are being studied. Donkey milk, as a nutritional support, has recently come into the spotlight with its anti-oxidant features, high antibody content and low allergenic properties. Read More

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http://dx.doi.org/10.5114/aoms.2016.59645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949905PMC
April 2018
22 Reads

Src Is a Prime Target Inhibited by Methanol Extract in Its Anti-Inflammatory Action.

Evid Based Complement Alternat Med 2018 14;2018:3909038. Epub 2018 Mar 14.

Department of Genetic Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.

is the traditional plant used at Korea as a herbal medicine to ameliorate inflammatory responses. Although has been traditionally used as a herbal medicine at Korea, no systemic research has been conducted on its anti-inflammatory activity. Therefore, the present study explored an anti-inflammatory effect and its underlying molecular mechanism using methanol extract (Cc-ME) in macrophage-mediated inflammatory responses. Read More

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http://dx.doi.org/10.1155/2018/3909038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872597PMC
March 2018
4 Reads

Diagnosis and treatment of acute phlegmonous gastritis: A case report.

Medicine (Baltimore) 2018 May;97(18):e0629

Gastrointestinal Surgery, the Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.

Rationale: Acute phlegmonous gastritis (PG) is a rare and often fatal condition mainly characterized by severe bacterial infection of the gastric wall. Case reports of PG over the past century average about 1 per year. Early diagnosis and immediate treatment are crucial to achieve positive outcomes. Read More

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http://dx.doi.org/10.1097/MD.0000000000010629DOI Listing

Acute Gastritis and Splenic Infarction Caused by Epstein-Barr Virus.

Pediatr Gastroenterol Hepatol Nutr 2018 Apr 13;21(2):147-153. Epub 2018 Apr 13.

Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Epstein-Barr virus (EBV) infection can be presented with various clinical manifestations and different levels of severity when infected. Infectious mononucleosis, which is most commonly caused by EBV infection in children and adolescents, is a clinical syndrome characterized by fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. But rarely, patients with infectious mononucleosis may present with gastrointestinal symptoms and complicated by gastritis, splenic infarction, and splenic rupture. Read More

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http://dx.doi.org/10.5223/pghn.2018.21.2.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915693PMC
April 2018
7 Reads

Typhlitis in a Patient with Acute Myelogenous Leukemia: A Case Report and Review of the Literature.

Case Rep Infect Dis 2018 11;2018:7510715. Epub 2018 Mar 11.

Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

is a Gram-positive rod that is now recognized as a rare cause of frank disease in the neutropenic hematologic malignancy patient. Because this pathogen is rarely isolated in clinical specimens, no large studies exist to guide the management of these acutely ill patients. Individual case reports and case series exist in the literature describing various clinical manifestations of in the neutropenic patient including bacteremia/septicemia, pneumonia, meningitis/encephalitis, hepatic abscesses, and gastritis. Read More

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http://dx.doi.org/10.1155/2018/7510715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866879PMC
March 2018
2 Reads

The aqueous extract from Artemisia capillaris inhibits acute gastric mucosal injury by inhibition of ROS and NF-kB.

Biomed Pharmacother 2018 Mar 20;99:681-687. Epub 2018 Feb 20.

College of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, 607 Obang-Dong, Gimhae, Gyungnam, 621-749, South Korea; u-Healthcare & Anti-Aging Rearch Center (u-HARC), Inje University, Gyeongnam, South Korea. Electronic address:

Artemisia capillaris, also called "InJin" in Korean, has been used as traditional oriental medicine in Korea because of its various pharmacological activities. These include hepatoprotective, analgesic, and antipyretic activities. The present study was designed to validate the beneficial effects of the aqueous extract of A. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07533322173449
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http://dx.doi.org/10.1016/j.biopha.2018.01.118DOI Listing
March 2018
8 Reads

Gastroprotective and Antioxidant Activity of and Leaf Juices against Indomethacin and Ethanol-Induced Gastric Lesions in Rats.

Int J Mol Sci 2018 Apr 24;19(5). Epub 2018 Apr 24.

Research Group on Bioactive Natural Products, Department of Pharmacy, Federal University of Rio Grande do Norte, 59012-570 Natal, Brazil.

and are used interchangeably in traditional medicine for treating peptic ulcers and inflammatory problems. In this context, this study aims to characterize the chemical constituents and evaluate the gastroprotective activity of the leaf juices of the two species in acute gastric lesions models. Thin Layer Chromatography (TLC) and Ultra High Performance Liquid Chromatography coupled to Mass Spectrometer (UHPLC-MS) were performed for chemical characterization. Read More

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http://dx.doi.org/10.3390/ijms19051265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983682PMC
April 2018
14 Reads

Inflammatory mechanism of Rumenitis in dairy cows with subacute ruminal acidosis.

BMC Vet Res 2018 Apr 19;14(1):135. Epub 2018 Apr 19.

Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, 5333 Xi'an Road, Changchun, Jilin, 130062, China.

Background: Subacute ruminal acidosis (SARA) is a metabolic disease in high-producing dairy cattle, and is accompanied by rumenitis. However, the mechanism of rumenitis remains unclear. Therefore, the aim of this study was to investigate the molecular mechanism of rumenitis in dairy cows with SARA. Read More

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http://dx.doi.org/10.1186/s12917-018-1463-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909223PMC
April 2018
2 Reads
1.780 Impact Factor

Severe acute gallstone pancreatitis with diffuse hemorrhagic gastritis.

J Surg Case Rep 2018 Mar 31;2018(3):rjy048. Epub 2018 Mar 31.

Department of Surgery, UAMS, Little Rock, AR 72204, USA.

A 67-year-old male presented with acute pancreatitis secondary to gallstones, also known as acute biliary pancreatitis, and subsequently developed gastric outlet obstruction and was transferred to our hospital. A gastro-jejunal feeding tube was placed and an open cholecystectomy was performed. The patient had a pancreatic drain placed for interval increase in pancreatic necrosis and then nearly exsanguinated from gastroduodenal artery pseudoaneurysm bleed. Read More

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http://dx.doi.org/10.1093/jscr/rjy048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887590PMC
March 2018
4 Reads

An unusual cause of gastrointestinal bleeding in a hemodialysis patient.

Hemodial Int 2018 Oct 2;22(4):E60-E62. Epub 2018 Apr 2.

AURA Paris Plaisance, Paris, France.

Iron deficiency caused by gastrointestinal (GI) bleeding is a common cause of anemia in hemodialysis patient. Herein, we report the case of an 89-year-old hemodialysis patient who presented with acute anemia and melena. Endoscopy found gastritis and diverticulosis without active bleeding. Read More

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http://dx.doi.org/10.1111/hdi.12657DOI Listing
October 2018
27 Reads

Phlegmonous Gastritis: A Report of Three Cases with Clinical and Imaging Features.

Intern Med 2018 Aug 30;57(15):2185-2188. Epub 2018 Mar 30.

Department of Gastroenterology, Graduate School of Medicine, Akita University, Japan.

Phlegmonous gastritis is a rare but often fatal acute pyogenic infection of the stomach. We herein report three cases of phlegmonous gastritis with different causes: the long-term placement of a nasogastric feeding tube, bacteremia associated with cellulitis in a diabetic patient, and an adverse reaction to paclitaxel/carboplatin chemotherapy for cancer of unknown primary cause, which were classified as primary, secondary, and idiopathic types, respectively. Coping with the increasing morbidity rate associated with the diverse background of such patients requires a thorough understanding of the clinical features and image findings associated with this entity. Read More

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http://dx.doi.org/10.2169/internalmedicine.0707-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120850PMC
August 2018
2 Reads

[Rare Clinical Case of a Small Intestine Ileus Following an Invaginated Meckel's Diverticulum].

Dtsch Med Wochenschr 2018 Mar 15;143(6):407-410. Epub 2018 Mar 15.

Klinik für Allgemein-, Viszeral-, Gefäß- & Transplantationschirurgie, Universitätsklinikum Magdeburg A.ö.R., Magdeburg.

Medical History And Clinical Findings:  A 43-year old male patient was admitted because of diffuse abdominal discomfort for two days, which had started in the upper abdomen; medical history, no previous surgical interventions at the abdomen.

Investigations:  Gastroscopy and abdominal ultrasound revealed only a mild gastritis. Laboratory parameters: showed only a slight leucocytosis (10 610/µL). Read More

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http://dx.doi.org/10.1055/s-0044-101965DOI Listing
March 2018
7 Reads

Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus.

Lancet Gastroenterol Hepatol 2018 04 7;3(4):271-280. Epub 2018 Mar 7.

Faculty of Health and Medicine, University of Newcastle, HMRI Building, New Lambton, NSW, Australia. Electronic address:

Under normal physiological conditions, eosinophils are present throughout the gastrointestinal tract distal to the squamous oesophagus. Increases in their numbers signify primary and secondary eosinophilic conditions. The rare primary eosinophilic diseases eosinophilic gastroenteritis and eosinophilic colitis affect fewer than ten in 100 000 people, and are characterised by numerous mucosal eosinophils, distributed in sheets and sometimes extending from the mucosa into the submucosa. Read More

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http://dx.doi.org/10.1016/S2468-1253(18)30005-0DOI Listing
April 2018
4 Reads

A new perspective on the pathogenesis of chronic renal disease in captive cheetahs (Acinonyx jubatus).

PLoS One 2018 7;13(3):e0194114. Epub 2018 Mar 7.

Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.

The sustainability of captive cheetah populations is limited by high mortality due to chronic renal disease. This necropsy study, conducted on 243 captive cheetahs from one institution, investigated the relationships between focal palatine erosions, gastritis, enterocolitis, glomerulosclerosis, chronic renal infarcts, renal cortical and medullary fibrosis, and renal medullary amyloidosis at death. Associations between the individual renal lesions and death due to chronic renal disease and comparisons of lesion prevalence between captive bred and wild born and between normal and king coated cheetahs were also assessed. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194114PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841817PMC
July 2018
2 Reads

In vivo anti-ulcerogenic effect of okra (Abelmoschus esculentus) on ethanol-induced acute gastric mucosal lesions.

Pharm Biol 2018 Dec;56(1):165-175

a Department of Bioengineering, Biochemistry Division, Faculty of Chem. and Met. Eng. , Yıldız Technical University , Istanbul , Turkey.

Context: Okra, Abelmoschus esculentus (L.) (Malvaceae), is a medicinal plant widely used in Turkish traditional medicine for the treatment of various diseases such as ulcers and gastritis.

Objective: In the present study, we evaluated the gastroprotective effect of okra against ethanol-induced acute gastric mucosal injury in animal models. Read More

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http://dx.doi.org/10.1080/13880209.2018.1442481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130549PMC
December 2018
9 Reads

Lafoensia pacari A. St.-Hil.: Wound healing activity and mechanism of action of standardized hydroethanolic leaves extract.

J Ethnopharmacol 2018 Jun 6;219:337-350. Epub 2018 Mar 6.

Área de Farmacologia, Departamento de Ciências Básicas em Saúde, Faculdade de Medicina, Universidade Federal de Mato Grosso (UFMT), Cuiabá, Brazil. Electronic address:

Ethnopharmacological Importance: Lafoensia pacari A. St.-Hil. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741173336
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http://dx.doi.org/10.1016/j.jep.2018.02.038DOI Listing
June 2018
19 Reads