2,159 results match your criteria Gastritis Acute


Pathology of Salmonella enterica Subspecies enterica Serotype Typhimurium Infection in Chinchillas (Chinchilla lanigera).

J Comp Pathol 2022 Jun 19;194:14-21. Epub 2022 Apr 19.

Setor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Septicaemia is the main pathological manifestation of Salmonella infection in chinchillas (Chinchilla lanigera), although information on its pathology is limited. We now describe the gross, histological and immunohistochemical features of Salmonella enterica subspecies enterica serotype Typhimurium (S. Typhimurium) infection in ranched chinchillas. Read More

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Prevalence of Autoimmune-phenomena behind Chronic Gastritis of Unknown Origin, and its Role in Poor Histological Outcome of the Stomach: A Single-centre, Retrospective Cross-sectional Study.

J Gastrointestin Liver Dis 2022 May 15. Epub 2022 May 15.

nstitute for Translational Medicine, Medical School, University of Pécs, Pécs; Division of Gastroenterology, First Department of Internal Medicine, Medical School, University of Pécs, Pécs, Hungary.

Background And Aims: The underlying aetiology of chronic gastritis (CG) often remains unknown due to its underrated significance in clinical practice. However, the role of chronic inflammation of the stomach in the development of atrophy, intestinal metaplasia (IM) and eventually of gastric cancer is well documented. We aimed to explore the possible aetiological factors of CG, determine the prevalence of systemic autoimmune disorders in patients with CG of unknown aetiology, and clarify the role of autoantibodies in the development of precancerous lesions in the stomach. Read More

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Case Report: Disseminated Strongloides stercoralis Presenting as an Ulcerated Gastric Mass in an HIV-1-infected Patient.

Am J Trop Med Hyg 2022 May 9. Epub 2022 May 9.

Mekelle University College of Health Sciences, Mekelle, Ethiopia.

Disseminated Strongloides stercoralis is a common phenomenon among patients with immunosuppression. In this report, we present a case of disseminated Strongloides stercoralis presenting as a gastric mass in a 42-year-old male patient with a known history of HIV-1 infection and type 2 diabetes mellitus (T2DM). The patient presented with symptoms and signs suggestive of acute on chronic erosive gastritis, which included persistent vomiting. Read More

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Momordica charantia polysaccharides alleviate diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and barrier via NF-κB pathway.

Allergol Immunopathol (Madr) 2022 1;50(3):62-70. Epub 2022 May 1.

Department of Digestive Internal Medicine, Lianyungang Hospital of Traditional Chinese Medicine, Lianyungang, Jiangsu, China;

Background: Momordica charantia exerts anti-inflammatory effect against ulcerative colitis. Momordica charantia polysaccharides (MCPs) attenuate gastritis through inhibition of ethanol-induced inflammatory response.

Objective: The role of MCPs in diarrhea-predominant irritable bowel syndrome (IBS-D) is investigated. Read More

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Comparative effectiveness of oral dexamethasone vs. oral prednisolone for acute exacerbation of asthma: A randomized control trial.

J Family Med Prim Care 2022 Apr 18;11(4):1395-1400. Epub 2022 Mar 18.

Department of Pediatrics, PGIMS, Rohtak, Haryana, India.

Background: Acute exacerbation of asthma is a common condition leading to emergency visits. Prednisolone is a commonly prescribed drug in the standard management of acute exacerbation of asthma along with other drugs. This study was planned to see the efficacy of oral dexamethasone when compared with oral prednisolone in the management of acute exacerbation of asthma. Read More

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Endoscopic Findings in Patients With Upper Gastrointestinal Bleeding in Ogun State, Nigeria.

Cureus 2022 Mar 30;14(3):e23637. Epub 2022 Mar 30.

Medicine, Babcock University Teaching Hospital, Ilishan-Remo, NGA.

Introduction Although the global incidence of upper gastrointestinal bleeding (UGIB) appears to have reduced substantially in the past few decades, acute UGIB still carries significant morbidity and mortality worldwide. There are currently no published data on UGIB in Ogun State, Nigeria. This study examined the endoscopic findings in patients with UGIB in Ogun State. Read More

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Octreotide-based therapies effectively protect mice from acute and chronic gastritis.

Eur J Pharmacol 2022 Apr 26:174976. Epub 2022 Apr 26.

State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism, China Pharmaceutical University, Nanjing, 210009, China. Electronic address:

Gastritis is a common inflammation of stomach with multiple pathogenesis. This study was designed to investigate the protective effects of oral octreotide (OCT) against ethanol-induced acute gastric injury and H. pylori-induced chronic gastritis via promoting gastric mucosa restoration, reducing gastric acid secretion and inflammation. Read More

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A Patient's Six-Month Journey From Low Sodium to Blue Toes to Stroke: Non-infective Thrombotic Endocarditis Due to Non-small Cell Lung Cancer.

Cureus 2022 Mar 16;14(3):e23235. Epub 2022 Mar 16.

Medicine, Zucker School of Medicine at Hofstra, Hempstead, USA.

We report a patient's journey with a four-year history of hypertension (HTN) and hyperlipidemia (HLD), stable on beta-blocker and statin, monitored every six months by alternating visits between her cardiologist and primary care physician (PCP) in North Carolina (NC). Six months before relocating to New York (NY) she had been informed about incidental severe hyponatremia during her last outpatient visit, the need for repletion with sodium chloride tablets, and the critical importance of prompt follow-up to rule out malignancy by starting with a chest X-ray. She opted not to follow instructions, continued cigarettes, and decided to spend the summer season with her son in NY. Read More

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Design, synthesis and in vivo evaluation of 1,4-dioxo-2-butenyl aryl amine derivatives as a promising anti-inflammatory drug prototype.

Bioorg Chem 2022 Mar 26:105754. Epub 2022 Mar 26.

Department of Pharmaceutical Sciences, College of Pharmacy, North Dakota State University, Fargo, ND 58078, United States. Electronic address:

Inflammation is a natural response of the organism to an infection, trauma, or cellular stress. Pain is the first symptom of acute and chronic inflammation. The standard class of medication to treat inflammatory pain is the nonsteroidal anti-inflammatory drug (NSAID). Read More

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Molecular Mechanism of against Gastric Damage and Identification of Active Compounds.

Biomolecules 2022 03 30;12(4). Epub 2022 Mar 30.

College of Korean Medicine, Gachon University, Seongnam 13120, Korea.

  is a natural product found in plants that has been used as a folk remedy for inflammation. In this study, we investigated the mechanism underlying the anti-inflammatory and antioxidant properties of   extract (ECC) in lipopolysaccharide (LPS)-induced murine RAW 264.7 cells, in comparison with 4-hydroxycinnamaldehyde, a extract component. Read More

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Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features.

Biomed Pharmacother 2022 Apr 19;150:112958. Epub 2022 Apr 19.

Faculty of Medicine of University of Coimbra, Portugal.

A narrative review of papers published from January 2011 to December 2021, after a literature search in selected databases using the terms "pharmacokinetics", "ibuprofen", "diclofenac", "acemetacin", "naproxen", "etodolac" and "etoricoxib" was performed. From 828 articles identified, only eight met the inclusion criteria. Selective COX-2 inhibitors are associated with higher cardiovascular risk, while non-selective COX inhibitors are associated with higher gastrointestinal risk. Read More

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Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases.

JAMA Oncol 2022 Apr 21. Epub 2022 Apr 21.

Center for Precision Medicine, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Knowledge about the spectrum of diseases associated with hereditary cancer syndromes may improve disease diagnosis and management for patients and help to identify high-risk individuals.

Objective: To identify phenotypes associated with hereditary cancer genes through a phenome-wide association study.

Design, Setting, And Participants: This phenome-wide association study used health data from participants in 3 cohorts. Read More

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Clinical Presentation of Cases with Upper Gastro - Intestinal Bleeding.

J Assoc Physicians India 2022 Apr;70(4):11-12

Care Hospitals, Nampally, Hyderabad.

Acute upper gastrointestinal bleeding (UGIB) is a common emergency and can be a serious condition that requires hospitalization, rapid evaluation and management. The usual presentation is hematemesis (vomiting of blood or coffee ground-like material) and/or melena (black, tarry stools) 1. UGIB occurs more commonly in men and older subjects. Read More

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[Acute Diseases of the Esophagus - Esophagitis].

Ther Umsch 2022 04;79(3-4):209-211

Klinik für Gastroenterologie, gastrointestinale Onkologie und Endokrinologie, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Deutschland.

Acute Diseases of the Esopagus - Esophagitis Inflammation of the esophagus can be caused by various conditions including gastroesophageal reflux (GERD), immunosuppression, infections, allergens, or distinct medications. GERD will be covered in a separate article. Clinical symptoms include heartburn, retrosternal pain, dysphagia, or fetor ex ore. Read More

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Stop of proton-pump inhibitor treatment in patients with liver cirrhosis (STOPPIT): study protocol for a prospective, multicentre, controlled, randomized, double-blind trial.

Trials 2022 Apr 12;23(1):302. Epub 2022 Apr 12.

I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: Proton-pump inhibitors (PPI) are liberally prescribed in patients with liver cirrhosis. Observational studies link PPI therapy in cirrhotic patients with an increased risk for infectious complications, hepatic encephalopathy and an increased risk for hospitalization and mortality. However, patients with liver cirrhosis are also considered to be at risk for peptic ulcer bleeding. Read More

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Anti-Inflammatory Activities of an Anti-Histamine Drug, Loratadine, by Suppressing TAK1 in AP-1 Pathway.

Int J Mol Sci 2022 Apr 3;23(7). Epub 2022 Apr 3.

Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.

Loratadine is an anti-histamine routinely used for treating allergies. However, recent findings have shown that Loratadine may also have anti-inflammatory functions, while their exact mechanisms have not yet been fully uncovered. In this paper, we investigated whether Loratadine can be utilized as an anti-inflammatory drug through a series of in vitro and in vivo experiments using a murine macrophage cell line and an acute gastritis mouse model. Read More

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The potential of dandelion in the fight against gastrointestinal diseases: A review.

J Ethnopharmacol 2022 Jul 8;293:115272. Epub 2022 Apr 8.

School of Chemical Sciences, The University of Auckland, Private Bag, 92019, Auckland, New Zealand. Electronic address:

Ethnopharmacological Relevance: Dandelion (Taraxacum officinale Weber ex F. H. Wigg. Read More

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Urease Levels and Gastritis Stage in Dyspeptic Patients.

Acta Med Indones 2022 Jan;54(1):42-51

1. Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital, Universitas Airlangga, Surabaya 60286, Indonesia 2. Institute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia 3. Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.

Background: Dyspepsia is a frequent main symptom of inpatients and outpatients scenario in Indonesia. However, the number of endoscopy facilities are still low, thus the use of non-invasive method to detect gastritis is necessary. We measured the relationship between urease levels and the stage of gastritis in dyspeptic adult patients. Read More

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January 2022

Urease, Gastric Bacteria and Gastritis.

Acta Med Indones 2022 Jan;54(1):1-2

Division of Gastroenterology, Department of Internal Medicine, Faculty Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Urease is an enzyme produced by diverse bacterial species including normal flora, non pathogens, and pathogens such as Proteus mirabilis, Staphylococcus saprophyticus, Klebsiella pneumonia, Citrobacter freundii, Enterobacter cloacae Helicobacter spp and Helicobacter pylori. Urease is central in Helicobacter pylori metabolism and virulence, important for colonization in the gastric mucosa. Urease catalyzes the hydrolysis of urea to ammonia and carbamate. Read More

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January 2022

Cytomegalovirus gastritis in a patient with severe acute respiratory syndrome coronavirus 2 infection: A case report and literature review.

Respir Med Case Rep 2022 2;37:101644. Epub 2022 Apr 2.

Internal Medicine Department, Shiraz University of Medical Sciences, Shiraz, Iran.

In this study, we reported a previously immunocompetent patient who developed cytomegalovirus-induced gastric ulcers after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. A 33-year-old man was referred to our center with complaints of persistent dysphagia and odynophagia, and epigastric pain and discomfort after ingesting solids or liquids, a few days after his hospital discharge following admission to treat coronavirus disease 2019 (Covid-19). Endoscopy revealed inflammation and a whitish exudate in the esophagus, and multiple large active ulcers in the stomach. Read More

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The incidence of eosinophilic oesophagitis in 2007-2017 among children in North Denmark Region is lower than expected.

BMC Pediatr 2022 04 6;22(1):183. Epub 2022 Apr 6.

Department of Clinical Medicine, Aalborg University, Frederik Bajers Vej 7D, 9220, Aalborg, Denmark.

Background: In North Denmark Region (NDR), the incidence of Eosinophilic Oesophagitis (EoE) among adults has increased following a new biopsy protocol in 2011, whereas data on the incidence of EoE among children is lacking.

Aims: To describe the incidence of EoE in children aged 0-17 in NDR as well as diagnostic delay, clinical manifestations, treatment and complications.

Methods: This retrospective, register-based DanEoE cohort study included 18 children diagnosed with EoE between 2007-2017 in NDR. Read More

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Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-C.

Front Immunol 2022 11;13:841126. Epub 2022 Mar 11.

Department of Pediatrics, Hadassah Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

The antibody profile against autoantigens previously associated with autoimmune diseases and other human proteins in patients with COVID-19 or multisystem inflammatory syndrome in children (MIS-C) remains poorly defined. Here we show that 30% of adults with COVID-19 had autoantibodies against the lung antigen KCNRG, and 34% had antibodies to the SLE-associated Smith-D3 protein. Children with COVID-19 rarely had autoantibodies; one of 59 children had GAD65 autoantibodies associated with acute onset of insulin-dependent diabetes. Read More

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Clinical Applications of Substance P (Neurokinin-1 Receptor) Antagonist in Canine Medicine.

Arch Razi Inst 2021 Nov 30;76(5):1175-1182. Epub 2021 Nov 30.

Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

Substance P binds to the Neurokinin-1 (NK-1) receptors found in the emetic center of the central nervous system (CNS) to induce emesis. Maropitant is a selective NK-1 receptor antagonist that inhibits the binding of substance P to NK-1 receptors and is commonly used to prevent and treat vomiting in dogs. This review study aimed to discuss and analyze the therapeutic potential of substance P (Neurokinin-1 receptor) antagonist with a particular focus on the drug maropitant in canine medicine. Read More

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November 2021

Mitigation of Gastric Damage Using Extract: Network Pharmacological Analysis of Active Compounds and Protection Effects in Rats.

Plants (Basel) 2022 Mar 8;11(6). Epub 2022 Mar 8.

Cooperative-Center of Natural Product Central Bank for Biological Evaluation, College of Korean Medicine, Gachon University, Seongnam 13120, Korea.

Gastritis is a common disease worldwide that is caused by various causes such as eating habits, smoking, severe stress, and heavy drinking, as well as infections and non-steroidal anti-inflammatory drugs. is a tropical aromatic evergreen tree commonly used as a natural medicine in Asia and as a functional food ingredient. Studies have reported this species' anti-obesity, anti-diabetic, and cardiovascular disease suppression effects. Read More

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Gut and liver involvement in pediatric hematolymphoid malignancies.

World J Gastrointest Oncol 2022 Mar;14(3):587-606

Department of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, Uttar Pradesh, India.

Hematolymphoid malignancies are common neoplasms in childhood. The involvement of the gastrointestinal (GI) tract, liver, biliary system, pancreas, and peritoneum are closely interlinked and commonly encountered. In leukemias, lymphomas, and Langerhans cell histiocytosis (LCH), the manifestations result from infiltration, compression, overwhelmed immune system, and chemotherapy-induced drug toxicities. Read More

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Immunological Perspective: Infection and Gastritis.

Authors:
Hang Yang Bing Hu

Mediators Inflamm 2022 8;2022:2944156. Epub 2022 Mar 8.

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

is a spiral-shaped gram-negative bacterium. Its infection is mainly transmitted via oral-oral and fecal-oral routes usually during early childhood. It can achieve persistent colonization by manipulating the host immune responses, which also causes mucosal damage and inflammation. Read More

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Rebamipide attenuates alcohol-induced gastric epithelial cell injury by inhibiting endoplasmic reticulum stress and activating autophagy-related proteins.

Eur J Pharmacol 2022 May 11;922:174891. Epub 2022 Mar 11.

Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. Electronic address:

Apoptosis of gastric mucosa epithelial cells caused by the abuse of alcohol produces injury to the gastric mucosa and acute or chronic gastritis. In recent years, it has been demonstrated that endoplasmic reticulum stress (ERS) is involved in mediating apoptosis, and that autophagy has a protective effect on survival of cells. Rebamipide is a gastric mucosal protectant used to treat gastritis and stomach ulcers. Read More

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Delayed Hemorrhagic Gastritis Caused by Immunotherapy in a Patient with Metastatic Melanoma.

Am J Med Sci 2022 Mar 8. Epub 2022 Mar 8.

Division of Medical Oncology/Hematology, Department of Medicine, University of Louisville, Louisville, KY, USA; James Graham Brown Cancer Center(,) University of Louisville, Louisville, KY, USA. Electronic address:

Pembrolizumab is a monoclonal antibody which targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes. It is commonly used to treat many types of malignancies. Immunotherapy-related adverse events are relatively common and include pneumonitis, colitis and hepatitis. Read More

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Acute phlegmonous gastritis: A case report.

J Am Coll Emerg Physicians Open 2022 Apr 28;3(2):e12640. Epub 2022 Feb 28.

Pediatric Fellowship Education, Pediatric Emergency Medicine Fellowship Program UH-Rainbow Babies and Children's Hospital CWRU School of Medicine Cleveland Ohio USA.

Acute phlegmonous gastritis (APG) is an extremely uncommon and potentially rapid fatal systemic infection with very few reported cases in the literature. This case report demonstrates a case of idiopathic APG in an afebrile, otherwise healthy individual that resolved with broad-spectrum antibiotic therapy and did not require operative management. Read More

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Portal Hypertensive Gastropathy in Liver Cirrhosis: Prevalence, Natural History, and Risk Factors.

Intern Med 2022 1;61(5):605-613. Epub 2022 Mar 1.

General Medical Center, Kawasaki Medical School, Department of General Internal Medicine 2, Japan.

Objective Portal hypertensive gastropathy (PHG) is a common finding in patients with liver cirrhosis (LC) and may cause both acute and chronic bleeding. A number of risk factors for PHG have been identified. The present study explored the characteristics of Japanese patients with LC who develop PHG. Read More

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