4,481 results match your criteria Gastric Carcinoma Imaging


Dynamic Contrast-Enhanced Ultrasound of Gastric Cancer: Correlation with Perfusion CT and Histopathology.

Korean J Radiol 2019 May;20(5):781-790

Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Objective: To assess the relationship between contrast-enhanced ultrasound (CEUS) parameters and perfusion CT (PCT) parameters of gastric cancers and their correlation with histologic features.

Materials And Methods: This prospective study was approved by our Institutional Review Board. We included 43 patients with pathologically-proven gastric cancers undergoing CEUS using SonoVue® (Bracco) and PCT on the same day. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3348/kjr.2018.02
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http://dx.doi.org/10.3348/kjr.2018.0273DOI Listing
May 2019
2 Reads

Mixed ductal-acinar cell carcinoma of the pancreas: A case report.

Mol Clin Oncol 2019 May 20;10(5):516-520. Epub 2019 Mar 20.

Department of Surgery, Kurume University Hospital, Kurume, Fukuoka 830-0011, Japan.

Mixed carcinoma of the pancreas is defined as the concurrent existence of pancreatic ductal carcinoma, acinar cell carcinoma, and/or islet cell carcinoma within the same neoplasm. We herein report a rare case of mixed ductal-acinar cell carcinoma in a 74-year-old man who was undergoing treatment for hypertension and diabetes at another hospital. After an abrupt worsening of his blood glucose control, the patient was referred to our hospital for further evaluation. Read More

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http://dx.doi.org/10.3892/mco.2019.1831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449909PMC

Gastric Heterotopic Pancreas Presenting as Abdominal Pain with Acute and Chronic Pancreatitis in the Resected Specimen.

Case Rep Gastrointest Med 2019 6;2019:2021712. Epub 2019 Mar 6.

Warren Alpert Medical School, Brown University, Providence, RI, USA.

Heterotopic pancreas, also known as ectopic pancreas, is pancreatic tissue located outside the pancreatic parenchyma without vascular or ductal communication with the gland. Ectopic pancreas is rarely symptomatic, typically detected incidentally at surgery or autopsy. Eighty-five to 90% are in the upper GI tract, especially the gastric antrum. Read More

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http://dx.doi.org/10.1155/2019/2021712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431401PMC
March 2019
2 Reads

Aggressive Graphic/Surgical R0 Resection and Jejunal Interposition with Preservation of Mesojejunal Autonomic Nerves in Patients with Stage IV Esophagogastric Junction Adenocarcinoma: A Report of 3 Cases.

Am J Case Rep 2019 Apr 6;20:465-473. Epub 2019 Apr 6.

Department of Digestive Surgery, Tenri Hospital, Tenri, Nara, Japan.

BACKGROUND Three patients with stage IV esophagogastric junction cancer (EGJC) underwent extended resection to achieve a graphic/surgical R0 status (no visible remnant of viable tumor in imaging/surgical findings) and adjuvant chemotherapy from the early postoperative period. We also introduced use of our digestive reconstruction technique in these patients. CASE REPORT We used jejunal interposition for digestive reconstruction, which involved end-to-end jejunojejunostomy with a biofragmentable anastomosis ring. Read More

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http://dx.doi.org/10.12659/AJCR.913960DOI Listing
April 2019
3 Reads

CT findings and clinical features of Epstein-Barr virus-associated lymphoepithelioma-like gastric carcinoma.

Medicine (Baltimore) 2019 Apr;98(14):e14839

Department of Pathology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China.

Epstein-Barr virus (EBV)-associated lymphoepithelioma-like gastric carcinoma (LELGC) is a rare primary stomach tumor, which has overlapping imaging features with mass forming gastric carcinoma (GC). The aim of our study was to present the computed tomography (CT) findings and clinical features of EBV-associated LELGC to increase awareness of this entity.The CT findings and clinical features of 4 patients with pathologically documented EBV-associated LELGC were retrospectively analyzed. Read More

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http://dx.doi.org/10.1097/MD.0000000000014839DOI Listing
April 2019
2 Reads

[Consensus on clinical application of transient elastography detecting liver fibrosis: a 2018 update].

Authors:

Zhonghua Gan Zang Bing Za Zhi 2019 Mar;27(3):182-191

Transient elastography is a noninvasive, rapid ultrasonic elastography, and assess liver fibrosis by detetcting liver stiffness. Current consensus focuses on understanding influence factors on operation and diagnosis, recommendations for clinical application on detetcting liver fibrosis of chronic liver disease and monitoring development of related complication hepatocelullar carcinoma, high risk esophageal varices, and also summarizes the potential aplication on liver disease screening and liver fibrosis regression assessment. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2019.03.004DOI Listing
March 2019
1 Read

Cholecystoduodenal fistula caused by aggressive mucinous gallbladder carcinoma with a porcelain gallbladder.

Clin J Gastroenterol 2019 Mar 27. Epub 2019 Mar 27.

Division of Gastroenterology, Shinko Hospital, 1-4-47 Wakihama-cho, Chuo-ku, Kobe, Hyogo, 651-0072, Japan.

Cholecystoduodenal fistula secondary to gallbladder carcinoma (GBC) is extremely rare and develops when the tumor penetrates into the adjacent duodenum. A porcelain gallbladder is also a very rare entity that involves the calcification of the gallbladder wall and can be associated with the development of GBC. Herein, we report an unusual case of a patient with cholecystoduodenal fistula, which has been caused by aggressive mucinous gallbladder carcinoma with a porcelain gallbladder. Read More

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http://dx.doi.org/10.1007/s12328-019-00969-9DOI Listing
March 2019
1 Read

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells.

Cells 2019 Mar 22;8(3). Epub 2019 Mar 22.

Institute of Biomedicine, University of Eastern Finland, 70211 Kuopio, Finland.

CD44 is a multifunctional adhesion molecule typically upregulated in malignant, inflamed and injured tissues. Due to its ability to bind multiple ligands present in the tumor microenvironment, it promotes multiple cellular functions related to tumorigenesis. Recent data has shown that CD44 and its principal ligand hyaluronan (HA) are carried by extracellular vesicles (EV) derived from stem and tumor cells, but the role of CD44 in EV shedding has not been studied so far. Read More

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https://www.mdpi.com/2073-4409/8/3/276
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http://dx.doi.org/10.3390/cells8030276DOI Listing
March 2019
5 Reads

The origin of p40-negative and CDX2-positive primary squamous cell carcinoma of the stomach: case report.

World J Surg Oncol 2019 Mar 19;17(1):53. Epub 2019 Mar 19.

Department of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.

Background: Primary gastric squamous cell carcinoma (SCC) is a very rare disease. The origin of this tumor remains unclear, although there are some hypotheses. A 60-year-old man consulted a previous physician complaining of upper abdominal pain. Read More

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http://dx.doi.org/10.1186/s12957-019-1594-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425685PMC
March 2019
2 Reads

Recombinant human thyrotropin (rhTSH) versus Levo-thyroxine withdrawal in radioiodine therapy of differentiated thyroid cancer patients: differences in abdominal absorbed dose.

Endocrine 2019 Mar 14. Epub 2019 Mar 14.

Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, Nuclear Medicine Unit, University of Messina, Messina, Italy.

Purpose: In DTC patients, 131-radioiodine therapy has routinely been used for many years for thyroid remnant ablation after thyroid surgery. To date, two different strategies can be used to achieve sufficient TSH stimulation on thyroid remnant: (I) Levo-thyroxine withdrawal or (II) rhTSH stimulation. The aim of our study was to compare the abdominal absorbed dose ratio between differentiated thyroid cancer patients who underwent thyroid remnant ablation after either L-T4 withdrawal or rhTSH stimulation. Read More

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http://dx.doi.org/10.1007/s12020-019-01897-xDOI Listing
March 2019
1 Read

Intestinal and diffuse gastric cancer: a retrospective study comparing primary sites.

Clin Imaging 2019 Mar 3;56:33-40. Epub 2019 Mar 3.

Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1473, Houston, TX 77030, United States of America. Electronic address:

Objective: We assessed differences in primary sites and spread patterns of the intestinal and diffuse subtypes of gastric carcinoma. We also compared survival outcomes based on spread patterns.

Materials And Methods: For this retrospective IRB-approved study, our institutional imaging database was mined for patients with gastric cancer. Read More

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http://dx.doi.org/10.1016/j.clinimag.2019.03.002DOI Listing
March 2019
1 Read

Impact of Tc-GSA SPECT Image-Guided Inverse Planning on Dose-Function Histogram Parameters for Stereotactic Body Radiation Therapy Planning for Patients With Hepatocellular Carcinoma: A Dosimetric Comparison Study.

Dose Response 2019 Jan-Mar;17(1):1559325819832149. Epub 2019 Mar 4.

Department of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.

Purpose: To evaluate the impact of Tc-labeled diethylene triamine pentaacetate-galactosyl human serum albumin (Tc-GSA) single-photon emission computed tomography (SPECT) image-guided inverse planning on the dose-function histogram (DFH) parameters for stereotactic body radiation therapy planning in patients with hepatocellular carcinoma (HCC).

Methods: Eleven patients were enrolled in this study. The functional liver structure (FLS) was derived from SPECT thresholds of 60% to 80% of the maximum pixel value. Read More

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http://dx.doi.org/10.1177/1559325819832149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402061PMC
March 2019
2 Reads

Calcified mucinous adenocarcinoma of the stomach metastatic to the iris: a case report.

J Med Case Rep 2019 Mar 7;13(1):64. Epub 2019 Mar 7.

Third Department of Internal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.

Background: Gastric cancer has a wide spectrum of clinical features, imaging manifestations, and pathology. Punctate calcifications in gastric cancer are infrequent but are usually found in mucinous adenocarcinoma. However, there have only been a few autopsy case reports describing the correlation between the radiology and pathology findings of calcified mucinous adenocarcinoma of the stomach. Read More

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http://dx.doi.org/10.1186/s13256-019-1977-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404271PMC
March 2019
3 Reads

Metastatic Tumors to the Pancreas, a Single Center Study.

Arch Iran Med 2019 Jan 1;22(1):50-52. Epub 2019 Jan 1.

Department of Hepatobiliary Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Most pancreatic masses are primary ductal adenocarcinomas; however, with the advent of new imaging studies and increasing survival of cancer patients, there are more cases with the diagnosis of secondary metastatic cancer to the pancreas. There is no study regarding cancer metastases to the pancreas from Iran. In this study, we retrieved all of the cases with the diagnosis of secondary cancer of pancreas in the affiliated hospitals of Shiraz University of Medical Sciences. Read More

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January 2019
2 Reads

Clinical and MRI Characteristics of Uterine Cervical Adenocarcinoma: Its Variants and Mimics.

Korean J Radiol 2019 Mar;20(3):364-377

Department of Radiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Adenocarcinoma currently accounts for 10-25% of all uterine cervical carcinomas and has a variety of histopathological subtypes. Among them, mucinous carcinoma gastric type is not associated with high-risk human papillomavirus (HPV) infection and a poor prognosis, while villoglandular carcinoma has an association with high-risk HPV infection and a good prognosis. They show relatively characteristic imaging findings which can be suggested by magnetic resonance imaging (MRI), though the former is sometimes difficult to be distinguished from lobular endocervical glandular hyperplasia. Read More

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http://dx.doi.org/10.3348/kjr.2018.0458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389813PMC

Activation of CD3 T cells by Helicobacter pylori DNA vaccines in potential immunotherapy of gastric carcinoma.

Cancer Biol Ther 2019 Feb 20:1-11. Epub 2019 Feb 20.

a Department of Oncology , Jinling Hospital, Nanjing University Clinical School of Medicine , Nanjing , China.

Most of gastric carcinoma (GC) is attributed to infection by Helicobacter pylori (H. pylori) but there is increasing evidence that the positive H. pylori status correlates with better prognosis in GC. Read More

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http://dx.doi.org/10.1080/15384047.2019.1579957DOI Listing
February 2019
1 Read

Validation of Baveno VI Criteria for Screening and Surveillance of Esophageal Varices in Patients With Compensated Cirrhosis and a Sustained Response to Antiviral Therapy.

Gastroenterology 2019 03 13;156(4):997-1009.e5. Epub 2019 Feb 13.

AP-HP, Hôpital Jean Verdier, Service d'Hépatologie, Bondy, Université Paris 13, Bobigny et INSERM U1162, Université Paris 5, Paris.

Background & Aims: Management of patients with cirrhosis includes endoscopic screening and surveillance to detect esophageal varices (EV) and prevent bleeding. However, the Baveno VI guidelines recommend avoiding endoscopies for patients with liver stiffness measurements below 20 kPa and platelet counts above 150,000 (favorable Baveno VI status) and endoscopic assessment of patients with higher levels of liver stiffness and platelet counts (unfavorable Baveno VI status). We aimed to validate the Baveno VI guidelines, evaluating outcomes of patients in the ANRS-CO12 CirVir cohort with compensated cirrhosis associated with hepatitis B virus (HBV) or hepatitis C virus (HCV) infection, with or without a sustained response to antiviral therapy. Read More

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http://dx.doi.org/10.1053/j.gastro.2018.11.053DOI Listing
March 2019
3 Reads

Risk of lymph node metastasis in undifferentiated-type mucosal gastric carcinoma.

World J Surg Oncol 2019 Feb 13;17(1):32. Epub 2019 Feb 13.

Department of Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Background: Endoscopic resection (ER) has come to be recognized as a standard treatment for early gastric cancer (EGC). While its adoption is expanding, ER remains restricted to cases of EGC without lymph node metastasis for the treatment of local resection. On the other hand, histopathological analyses of surgically resected specimens of EGC have revealed the presence of lymph node (LN) metastasis in some cases of mucosal gastric cancer (MGC) and undifferentiated MGC (UD-MGC) is considered to have higher risk of nodal metastases than differentiated MGC (D-MGC). Read More

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http://dx.doi.org/10.1186/s12957-019-1571-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375195PMC
February 2019
1 Read

A case of human pancreatic eurytremiasis.

Abdom Radiol (NY) 2019 Apr;44(4):1213-1216

Department of Pathology and Laboratory Medicine, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8560, Japan.

This study provides the first comprehensive imaging report of human pancreatic eurytremiasis. A 43-year-old man with obstructive jaundice and a pancreatic tumor was referred for diagnosis and treatment. Serum aspartate aminotransferase, alanine aminotransferase, and gamma-glutamyl transpeptidase were elevated. Read More

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http://dx.doi.org/10.1007/s00261-019-01925-4DOI Listing
April 2019
1 Read

Transhepatic forceps biopsy after PTCD for histological assessment of bile duct stenoses or occlusions.

Z Gastroenterol 2019 Feb 12;57(2):133-138. Epub 2019 Feb 12.

Institute of Radiology and Nuclear Medicine, Klinikum Nürnberg Nord, Nürnberg, Germany.

Purpose:  The goal of this study was to evaluate the experience of 11 years of wire-guided forceps biopsy via PTCD in patients with obstructive jaundice.

Materials And Methods:  In a retrospective approach, 56 biopsies in 51 patients were analyzed (22 female, 29 male). Data was collected from 2006 to 2016. Read More

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http://dx.doi.org/10.1055/a-0821-7060DOI Listing
February 2019
2 Reads

Immuno-PET Imaging and Pharmacokinetics of an Anti-CEA scFv-based Trimerbody and Its Monomeric Counterpart in Human Gastric Carcinoma-Bearing Mice.

Mol Pharm 2019 Mar 18;16(3):1025-1035. Epub 2019 Feb 18.

Radiochemistry and Nuclear Imaging Group , CIC biomaGUNE , 20014 San Sebastián , Guipúzcoa , Spain.

Monoclonal antibodies (mAbs) are currently used as therapeutic agents in different types of cancer. However, mAbs and antibody fragments developed so far show suboptimal properties in terms of circulation time and tumor penetration/retention. Here, we report the radiolabeling, pharmacokinetic evaluation, and determination of tumor targeting capacity of the previously validated anti-CEA MFE23-scFv-based N-terminal trimerbody (MFE23-trimerbody), and the results are compared to those obtained for the monomeric MFE23-scFv. Read More

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b01006DOI Listing
March 2019
3 Reads

[Application of intracorporeal uncut Roux-en-Y anastomosis in digestive tract reconstruction after laparoscopic total gastrectomy].

Zhonghua Wei Chang Wai Ke Za Zhi 2019 Jan;22(1):43-48

Department of Oncology Surgery, Fujian Provincial Hospital, Fuzhou 350001,

Objective: To explore the safety, feasibility and short-term efficacy of intracavitary uncut Roux-en-Y (URY) anastomosis in digestive tract reconstruction following laparoscopic total gastrectomy (LTG).

Methods: From November 2015 to January 2018, 67 gastric cancer patients underwent intracavitary URY following LTG to reconstruct the digestive tract at Oncological Surgery Department of Fujian Provincial Hospital. There were 41 males and 26 females with age of 50 to 81 (61. Read More

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January 2019
2 Reads

Treatment for gastric 'indefinite for neoplasm/dysplasia' lesions based on predictive factors.

World J Gastroenterol 2019 Jan;25(4):469-484

Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, South Korea.

Background: Gastric 'indefinite for neoplasm/dysplasia' (IFND) is a borderline lesion that is difficult to diagnose as either regenerative or neoplastic. There is a need for guidance in the identification of a subset of patients, who have an IFND lesion with a higher risk of malignant potential, to enable risk stratification and optimal management.

Aim: To determine the clinical and pathologic factors for the accurate diagnosis of gastric IFND lesions. Read More

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http://dx.doi.org/10.3748/wjg.v25.i4.469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350171PMC
January 2019
5 Reads

Narrow-Band Imaging: Clinical Application in Gastrointestinal Endoscopy.

GE Port J Gastroenterol 2018 Dec 27;26(1):40-53. Epub 2018 Mar 27.

Department of Gastroenterology, Instituto Português de Oncologia do Porto, Porto, Portugal.

Narrow-band imaging is an advanced imaging system that applies optic digital methods to enhance endoscopic images and improves visualization of the mucosal surface architecture and microvascular pattern. Narrow-band imaging use has been suggested to be an important adjunctive tool to white-light endoscopy to improve the detection of lesions in the digestive tract. Importantly, it also allows the distinction between benign and malignant lesions, targeting biopsies, prediction of the risk of invasive cancer, delimitation of resection margins, and identification of residual neoplasia in a scar. Read More

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https://www.karger.com/Article/FullText/487470
Publisher Site
http://dx.doi.org/10.1159/000487470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341367PMC
December 2018
8 Reads

[PRIMARY SMALL CELL NEUROENDOCRINE CARCINOMA OF THE URETER].

Nihon Hinyokika Gakkai Zasshi 2018 ;109(1):30-34

Departments of Pathology, Kinki Central Hospital of Mutual Aid Association of Public Teachers.

Primary small cell neuroendocrine carcinoma of the upper urinary tract is a rare disease that is associated with a poor prognosis. An 81-year-old man was diagnosed with carcinoma of the stomach and underwent laparoscopic distal gastrectomy. Computed tomography (CT) revealed carcinoma of the left ureter and left hydronephrosis. Read More

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http://dx.doi.org/10.5980/jpnjurol.109.30DOI Listing
February 2019
1 Read

Seminal vesicle metastasis after liver transplantation for hepatocellular carcinoma: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e13770

Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University, Medical School.

Rationale: Cancer recurrence and metastasis after liver transplantation (LT) is common in some hepatocellular carcinoma (HCC) patients. The most common sites of extrahepatic metastases are lung, regional lymph node, adrenal gland, and bone. To our knowledge, HCC metastasis to the seminal vesicle after LT has not been reported in the literature. Read More

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http://dx.doi.org/10.1097/MD.0000000000013770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370123PMC
January 2019
4 Reads

Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m.

Pharmaceuticals (Basel) 2019 Jan 15;12(1). Epub 2019 Jan 15.

Department of Nuclear Medicine, Medical University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria.

The high overexpression of cholecystokinin-2 receptors (CCK2R) in tumors, such as medullary thyroid carcinoma, allows for highly specific diagnostic and therapeutic targeting with radiolabeled peptide probes derived from natural ligands for the receptor. Based on the ideal imaging characteristics, high availability and low cost of technetium-99m (Tc)-labeled radiopharmaceuticals we have developed two hydrazinonicotinic acid (HYNIC) conjugated minigastrin analogs allowing labeling at high specific activity. The CCK2R targeting peptide conjugates show specific amino acid substitutions in the C-terminal receptor-specific sequence with the aim to increase stability and tumor targeting. Read More

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http://www.mdpi.com/1424-8247/12/1/13
Publisher Site
http://dx.doi.org/10.3390/ph12010013DOI Listing
January 2019
10 Reads

SMARCB1- and vimentin-positive esophageal carcinoma with undifferentiated components, rhabdoid features, and a good prognosis: a case report.

Surg Case Rep 2019 Jan 16;5(1). Epub 2019 Jan 16.

1st Department of Surgery, Faculty of Medicine, University of Fukui, 23-3 Matsuokashimoaizuki, Yoshida-gun, Eiheiji-cho, Fukui, 910-1193, Japan.

Background: Undifferentiated carcinoma of the esophagus with rhabdoid features is a very rare histologic finding that is occasionally associated with the loss of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1); however, until now, few survey reports of this type of tumor have been published. In this study, we describe a case of esophageal carcinoma with undifferentiated components and rhabdoid features that was exclusively positive for vimentin and SMARCB1 in a patient with prolonged survival.

Case Presentation: A 67-year-old man complained of a stomachache and loss of appetite persisting for 1 month. Read More

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https://surgicalcasereports.springeropen.com/articles/10.118
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http://dx.doi.org/10.1186/s40792-019-0562-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335233PMC
January 2019
8 Reads

Liver Metastasis of Hepatoid Colonic Adenocarcinoma: A Rare and Unusual Entity With Poor Prognosis and Review of the Literature.

Gastroenterology Res 2018 Dec 17;11(6):430-435. Epub 2018 Dec 17.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.

Hepatoid adenocarcinoma (HAC) is rare and was first reported as α-fetoprotein (AFP)-producing tumor. It is an important variant of extrahepatic adenocarcinoma with clinicopathological presentation mimicking hepatocellular carcinoma and carries exceedingly poor prognosis. HAC most commonly originates in the stomach, and less commonly in the ovary, esophagus, lung, among other organs. Read More

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http://dx.doi.org/10.14740/gr1097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306111PMC
December 2018
4 Reads

Gastric Ulcer Mimicking Malignancy on FDG PET/CT.

Clin Nucl Med 2019 Feb;44(2):142-144

Department of Nuclear Medicine, Zigong First People's Hospital, Zigong, Sichuan.

A 52-year-old woman with newly diagnosed cervical carcinoma was referred an F-FDG PET/CT for staging. The PET/CT images demonstrated the known carcinoma and multiple enlarged lymph nodes with increased FDG activity. In addition, there was a focus of intense FDG activity characteristic of hypermetabolic malignancy in the region of gastric antrum. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002379DOI Listing
February 2019
1 Read

Primary Gastric Yolk Sac Tumour.

Sultan Qaboos Univ Med J 2018 Aug 19;18(3):e383-e385. Epub 2018 Dec 19.

Department of Radiology & Molecular Imaging, Sultan Qaboos University Hospital, Muscat, Oman.

Primary gastric yolk tumours are extremely rare. We report a 52-year-old male who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2017 after having undergone a gastrectomy abroad due to a suspected poorly-differentiated adenocarcinoma. The patient subsequently returned to Oman to receive chemotherapy. Read More

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https://journals.squ.edu.om/index.php/squmj/article/view/286
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http://dx.doi.org/10.18295/squmj.2018.18.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307656PMC
August 2018
4 Reads

Is there association of gross tumor volume of adenocarcinoma of oesophagogastric junction measured on magnetic resonance imaging with N stage?

Eur J Radiol 2019 Jan 22;110:181-186. Epub 2018 May 22.

Sichuan Key Laboratory of Medical Imaging, and Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 63# Wenhua Road, Shunqing District, Nanchong 637000, Sichuan, China.

Purpose: To determine whether gross tumour volume (GTV) of adenocarcinoma of oesophagogastric junction (AOG) measured on fat-suppression T-weighted imaging (FS-TWI) and diffusion-weighted imaging (DWI) correlates with regional lymph node metastasis and N stage.

Materials And Methods: The study was approved by the institutional ethics committee, and written informed consent was obtained. Forty-six patients with AOG underwent preoperative magnetic resonance scans including FS-TWI and DWI with b-values of 500 and 800 s/mm. Read More

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http://dx.doi.org/10.1016/j.ejrad.2018.05.023DOI Listing
January 2019
3 Reads

Endoscopic and clinicopathological features of intramucosal, histologically mixed-type, low-grade, well-differentiated gastric tubular adenocarcinoma with the potential for late-onset lymph node metastasis.

BMC Gastroenterol 2018 Dec 27;18(1):189. Epub 2018 Dec 27.

Department of Pathology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Chuo-ku, Niigata, 951-8566, Japan.

Background: Intramucosal, histologically mixed-type, low-grade (LG), well-differentiated gastric tubular adenocarcinomas (tub1s; LG-tub1s) have larger mean diameters and exhibit a higher frequency of the gastric mucin phenotype (G-phenotype) than pure LG-tub1s. In proportion to their increases in diameter, G-phenotype differentiated-type early gastric cancer (EGC) tumours reportedly grow to eventually contain (an) undifferentiated-type component(s) and LG-tub1s, which are included in differentiated-type EGCs, reportedly exhibit changes in their glandular architectural and cytological atypia grades from LG to high-grade (HG) and can grow to contain a moderately differentiated tubular adenocarcinoma (tub2) component and undifferentiated components. Because they generally show a higher frequency of malignancy relative to tumours with a higher atypia grade and lower differentiation degree, it is suggested that, among mixed-type LG-tub1s, G-phenotype LG-tub1s containing an HG-tub2 component (LG-tub1s > HG-tub2) with undifferentiated components might lead to late-onset metastasis to lymph nodes even after a successful endoscopic submucosal dissection (ESD). Read More

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https://bmcgastroenterol.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/s12876-018-0919-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307236PMC
December 2018
9 Reads

A case report of endoscopic therapy for radiation-induced hemorrhagic gastritis in patient with recurrent hepatocellular carcinoma.

Medicine (Baltimore) 2018 Dec;97(51):e13535

Department of Digestive Disease, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University.

Rationale: Radiation-induced hemorrhagic gastritis is an infrequent cause of upper gastrointestinal bleeding and difficult to manage. The current standard treatment has not been well established.

Patient Concerns: We described a 32-year-old male patient with hemorrhagic gastritis induced by external radiotherapy for hepatocellular carcinoma recurrence. Read More

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http://dx.doi.org/10.1097/MD.0000000000013535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320029PMC
December 2018
4 Reads

Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus: The Phase 2 KEYNOTE-180 Study.

JAMA Oncol 2018 Dec 20. Epub 2018 Dec 20.

Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

Importance: Effective treatment options are limited for patients with advanced, metastatic esophageal cancer progressing after 2 or more lines of systemic therapy.

Objective: To evaluate the efficacy and safety of pembrolizumab for patients with advanced, metastatic esophageal squamous cell carcinoma (ESCC) or advanced, metastatic adenocarcinoma of the esophagus and gastroesophageal junction that progressed after 2 or more lines of systemic therapy.

Design, Setting, And Participants: This phase 2, open-label, interventional, single-arm study, KEYNOTE-180, enrolled 121 patients from January 12, 2016, to March 21, 2017, from 57 sites in 10 countries. Read More

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http://dx.doi.org/10.1001/jamaoncol.2018.5441DOI Listing
December 2018
5 Reads

Copy number variation profile in noninvasive prenatal testing (NIPT) can identify co-existing maternal malignancies: Case reports and a literature review.

Taiwan J Obstet Gynecol 2018 Dec;57(6):871-877

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

Objective: The coexistence of maternal malignancy and pregnancy has received increasing attention in Noninvasive prenatal testing (NIPT) studies. Malignancy in pregnant women potentially affects the copy number variation (CNV) profile in NIPT results. Only one case of hematologic cancer has been reported in a Hong-Kong pregnant women, and solid tumors have never been reported in pregnant Chinese women. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10284559183025
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http://dx.doi.org/10.1016/j.tjog.2018.10.032DOI Listing
December 2018
28 Reads

[A Case of Autopsy of Sarcomatoid Carcinoma of the Penis with Metastasis to the Right Ventricle of the Heart].

Hinyokika Kiyo 2018 Nov;64(11):455-458

The Department of Pathology, National Hospital Organization Osaka Minami Medical Center.

A 75-year-old man with a history of early gastric cancer, phimosis and bronchial asthma experienced pain and palpated a mass in the penis in March 2015. After 2 months, he noticed bleeding from the tumor and visited our hospital. Pelvic computed tomography and magnetic resonance imaging revealed a pelvic tumor, bilateral lymphadenopathy, and para-aortic lymphadenopathy. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_64_11_455DOI Listing
November 2018
16 Reads

Biodistribution, pharmacokinetics, and organ-level dosimetry for Re-AHDD-Lipiodol radioembolization based on quantitative post-treatment SPECT/CT scans.

EJNMMI Phys 2018 Dec 7;5(1):30. Epub 2018 Dec 7.

Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.

Background: Rhenium-188-labelled-Lipiodol radioembolization is a safe and cost-effective treatment for primary liver cancer. In order to determine correlations between treatment doses and patient response to therapy, accurate patient-specific dosimetry is required. Up to date, the reported dosimetry of Re-Lipiodol has been based on whole-body (WB) planar imaging only, which has limited quantitative accuracy. Read More

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http://dx.doi.org/10.1186/s40658-018-0227-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283804PMC
December 2018
1 Read

Gastric metastasis of recurrent hepatocellular carcinoma: A case report and literature review.

J Cancer Res Ther 2018 Dec;14(Supplement):S1230-S1232

Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.

Hepatocellular carcinoma (HCC) with gastric metastasis is seldom reported. It is extremely easy to misdiagnose for primary gastric cancer with liver metastasis, especially gastric hepatoid adenocarcinoma. Here, we report a case of recurrent HCC with gastric metastasis in a 22-year-old man. Read More

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http://www.cancerjournal.net/text.asp?2018/14/7/1230/199379
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http://dx.doi.org/10.4103/0973-1482.199379DOI Listing
December 2018
10 Reads

Isolated antro-pyloric metastatic mass from colonic carcinoma: A rare case presentation.

Ann Med Surg (Lond) 2018 12 22;36:235-238. Epub 2018 Nov 22.

Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, India.

Metastatic tumors to stomach are extremely rare with very few cases being described so far in the surgical literature. Colonic tumors metastatic to stomach represent a rarer entity and present a surgical challenge for diagnosis and management to the clinician. We, hereby present a case of adenocarcinoma of transverse colon metastatic to stomach more than 6 years after the index malignancy, presenting clinically with features of gastric outlet obstruction. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260385PMC
December 2018
2 Reads

Acquired hemophilia A in solid cancer: Two case reports and review of the literature.

World J Clin Cases 2018 Nov;6(14):781-785

Department of Internal Medicine, Health Sciences University of Hokkaido, Toubetsu 0610293, Japan.

Acquired hemophilia A (AHA) is a rare, hemorrhagic autoimmune disease, whose pathogenesis involves reduced coagulation factor VIII (FVIII) activity related to the appearance of inhibitors against FVIII. Common etiological factors include autoimmune diseases, malignancy, and pregnancy. We report two cases of AHA in solid cancer. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i14.781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264993PMC
November 2018
2 Reads

[Value of double contrast-enhanced ultrasound QontraXt three-dimensional pseudocolor quantitative analysis to therapeutic effect evaluation of preoperative neoadjuvant chemotherapy in advanced gastric cancer patients].

Zhonghua Zhong Liu Za Zhi 2018 Nov;40(11):857-863

Department of Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China.

To investigate the value of tumor perfusion parameter measured by using double contrast-enhanced ultrasound (DCEUS) QontraXt three-dimensional pseudocolor quantitative analysis to the therapeutic effect evaluation of preoperative neoadjuvant chemotherapy (NAC) in advanced gastric cancer (AGC) patients. Eighty-nine AGC patients underwent 3 cycles of preoperative NAC (XELOX) followed by complete resection of lesion. The DCEUS QontraXt three-dimensional pseudocolor was performed one or two weeks before the NAC and operation were applied, respectively. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2018.11.012DOI Listing
November 2018
8 Reads

Compensatory gastric stretching following subtotal gastric resection due to gastric adenocarcinoma in a diamond python (Morelia spilota spilota).

Aust Vet J 2018 Dec;96(12):481-486

Avian Reptile and Exotic Pet Hospital, School of Veterinary Science, University of Sydney, Camden, 2570, New South Wales, Australia.

Case Report: A 7-year-old male diamond python (Morelia spilota spilota) presented with a 2-month history of anorexia and a discrete intracoelomic mass, approximately 15 cm in length, located 90 cm from the head and approximately two-thirds of the snout to vent length. Physical examination determined the mass was likely to be stomach, testes or the right kidney. Radiographs showed a soft tissue opacity mass in the region of the stomach; fine needle aspirate demonstrated cellular debris admixed with bacteria and degenerate heterophils. Read More

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http://doi.wiley.com/10.1111/avj.12764
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http://dx.doi.org/10.1111/avj.12764DOI Listing
December 2018
2 Reads

Characterization of gastric cells infection by diverse Helicobacter pylori strains through Fourier-transform infrared spectroscopy.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Mar 5;210:193-202. Epub 2018 Nov 5.

ISEL-Instituto Superior de Engenharia de Lisboa, Instituto Politécnico de Lisboa, Rua Conselheiro Emídio Navarro 1, 1959-007 Lisboa, Portugal. Electronic address:

The infection of Helicobacter pylori, covering 50% of the world-population, leads to diverse gastric diseases as ulcers and cancer along the life-time of the human host. To promote the discovery of biomarkers of bacterial infection, in the present work, Fourier-transform infrared spectra were acquired from adenocarcinoma gastric cells, incubated with H. pylori strains presenting different genotypes concerning the virulent factors cytotoxin associated gene A and vacuolating cytotoxin A. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13861425183099
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http://dx.doi.org/10.1016/j.saa.2018.11.001DOI Listing
March 2019
27 Reads

Detection of gastric cancer and its histological type based on iodine concentration in spectral CT.

Cancer Imaging 2018 Nov 9;18(1):42. Epub 2018 Nov 9.

Department of Radiology, the First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou, 450052, Henan, China.

Background: Computed tomography (CT) imaging is the most common imaging modality for the diagnosis and staging of gastric cancer. The aim of this study is was to prospectively explore the ability of quantitative spectral CT parameters in the detection of gastric cancer and its histologic types.

Methods: A total of 87 gastric adenocarcinoma (43 poorly and 44 well-differentiated) patients and 36 patients with benign gastric wall lesions (25 inflammation and 11 normal), who underwent dual-phase enhanced spectral CT examination, were retrospectively enrolled in this study. Read More

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http://dx.doi.org/10.1186/s40644-018-0176-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230291PMC
November 2018
2 Reads

Synchronous Colonic Adenocarcinoma and Metastatic Lobular Carcinoma in a Colectomy Specimen: A Rare Finding.

Cureus 2018 Aug 27;10(8):e3207. Epub 2018 Aug 27.

Department of Surgery, "Saint Savvas" Cancer Hospital, Athens, GRC.

Invasive lobular carcinoma is the second-most-common subtype of invasive breast carcinoma. Its metastatic pattern is different compared to invasive carcinoma-no special type. It metastasizes more often to the gastrointestinal tract, peritoneum, pleura, and ovaries. Read More

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http://dx.doi.org/10.7759/cureus.3207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205883PMC
August 2018
5 Reads

Gastric outlet obstruction caused by metastatic tumor of the stomach originating from primary breast cancer: A case report.

Mol Clin Oncol 2018 Nov 17;9(5):523-526. Epub 2018 Sep 17.

Department of Surgery, Kochi Medical School, Nankoku, Kochi 783-8505, Japan.

The most common sites of breast cancer metastasis are the bone, liver, lung and brain, while gastrointestinal metastasis from breast cancer is rare. We herein present the case of a 68-year-old woman who was admitted to our department with nausea and appetite loss. The patient's medical history included right mastectomy with sentinel lymph node biopsy 5 years earlier for invasive lobular carcinoma, measuring 6. Read More

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http://www.spandidos-publications.com/10.3892/mco.2018.1722
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http://dx.doi.org/10.3892/mco.2018.1722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200976PMC
November 2018
25 Reads

Computed tomography and magnetic resonance imaging findings of metastatic rectal linitis plastica from prostate cancer: A case report and review of literature.

World J Clin Cases 2018 Oct;6(12):554-558

Department of Surgery, Chonbuk National University Medical School and Hospital, Jeonju 54907, Chonbuk, South Korea.

Linitis plastica is a rare condition showing circumferentially infiltrating intramural anaplastic carcinoma in a hollow viscus, resulting in a tissue thickening of the involved organ as constricted, inelastic, and rigid. While most secondary rectal linitis plastica (RLP) is caused by metastasis from stomach, breast, gallbladder, or bladder cancer, we report an extremely rare and unique case of secondary RLP due to prostate cancer with computed tomography (CT) and magnetic resonance imaging (MRI) findings, including diffusion weighted imaging (DWI). A 78-year-old man presented with approximately a 2-mo history of constipation and without cancer history. Read More

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http://www.wjgnet.com/2307-8960/full/v6/i12/554.htm
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http://dx.doi.org/10.12998/wjcc.v6.i12.554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212608PMC
October 2018
12 Reads

[Synchronous gastrointestinal stromal tumor of stomach and invasive ductal carcinoma of both breasts].

Pol Merkur Lekarski 2018 Oct;45(268):161-163

Department of Oncologic Surgery, Medical University of Gdańsk, Poland.

Gastrointestinal stromal tumor (GIST), despite the fact that it accounts for less than 5% of all sarcomas, is the most common mesenchymal tumor of the alimentary canal. Synchronous and metachronous stromal tumors are very rare findings. Only a few such cases can be found in the literature, and yet most of them is connected with Von Recklinghausen's disease or Carney's triad in which it is proved a much higher frequency of occurrence of this kind of tumors. Read More

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October 2018
4 Reads