Obstet Gynecol 2022 Jun 2;139(6):1092-1102. Epub 2022 May 2.
Daré Bioscience, Inc., San Diego, California; the University of Pittsburgh and Magee-Womens Research Institute, Pittsburgh, Pennsylvania; Gendreau Consulting, LLC, Poway, California; Health Decisions, Inc., Durham, North Carolina; Segal Trials and the University of Miami Miller School of Medicine, Miami, Florida; Precision Trials AZ, LLC, Phoenix, Arizona; Praetorian Pharmaceutical Research and West Jefferson Medical Center, Marrero, Louisiana; Southern Clinical Research Associates, LLC, Metairie, Louisiana; and TMC Life Research, Inc., Houston, Texas.
Objective: To assess efficacy and safety of a single-dose vaginal clindamycin gel for bacterial vaginosis treatment.
Methods: We conducted a double-blind, placebo-controlled, randomized study comparing clindamycin gel with placebo (2:1 ratio). Entry required clinical diagnosis of bacterial vaginosis, that is, all four Amsel's criteria, without other genital infections. Read More