Stroke 2016 Jul 14;47(7):1710-3. Epub 2016 Jun 14.
From the Department of Neurosurgery, King's College Hospital, London, United Kingdom (P.B., C.M.T.); Departments of Neurosurgery (P.B., F.R.P.) and Orthopaedic Surgery (J.L.), Odense University Hospital, Denmark; Molecular Haematology, King's College London, London, United Kingdom (K.G., S.L.T.); Department of Haematology, Guy's and St. Thomas Hospital, London, United Kingdom (R.K.-A.); Department of Anaesthetics, Derriford Hospital, Plymouth, United Kingdom (J.D.); Institute of Clinical Research, University of Southern Denmark, Odense, Denmark (J.L., F.R.P.); and Sickle Cell Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD (S.L.T.).
Background And Purpose
: Intracranial aneurysms and aneurysmal subarachnoid hemorrhage may occur more frequently in sickle-cell disease (SCD), and this could be related to the sickle genotype and moyamoya syndrome seen in SCD.Methods
: Records from a total of 1002 patients with SCD attending 2 specialized adult hematologic services were retrospectively reviewed. We analyzed data of a cohort of 767 patients attending 1 SCD clinic between 2002 and 2013 and of 235 patients from the other clinic who have had neurovascular imaging between 2007 and 2014. Read More