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Psychiatr Pol 2022 Feb 27;56(1):63-75. Epub 2022 Feb 27.

Warszawski Uniwersytet Medyczny, Katedra i Klinika Psychiatryczna.

Ganser syndrome (GS) is one of afew eponyms that have survived in psychiatry until the present day. GS is a little-known and rare disorder. It is most often described as a response to a stressor (e. Read More

Arch Clin Neuropsychol 2022 Apr 28. Epub 2022 Apr 28.

Academic Neurology Unit, University of Sheffield, Sheffield, UK.

Background: Cognitive symptoms in the absence of neurological disease are common. Functional cognitive disorder (FCD) has been conceptualized as a cognitive subtype of functional neurological disorder. Although FCD is understood as different from exaggerated or feigned cognitive complaints, previous accounts have provided little practical advice on how FCD can be separated from factitious or malingered cognitive complaints. Read More

Bone Marrow Transplant 2022 Apr 22. Epub 2022 Apr 22.

CHU de Lille, Univ Lille, INSERM U1286, INFINITE, 59000, Lille, France.

We performed a registry study on therapy-related myeloid neoplasm (t-MN), both therapy-related myelodysplastic syndrome (t-MDS) and acute myeloid leukemia (t-AML) following treatment for breast cancer who underwent a first allogeneic hematopoietic cell transplant (allo-HCT). Of 252 identified female patients (median age 57 years), 77% were transplanted for t-AML and 23% for t-MDS, with a median time from breast cancer diagnosis to the diagnosis of tMN and subsequent allo-HCT of 3.7 and 4. Read More

Harv Rev Psychiatry 2022 May-Jun 01;30(3):207-213. Epub 2022 Apr 15.

From Harvard Medical School (Drs. Peng, Koire, and Jimenez-Madiedo); Department of Psychiatry, Brigham and Women's Hospital, Boston, MA (Drs. Peng, Koire, and Jimenez-Madiedo); Department of Psychiatry, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA (Dr. Eisendrath); Office of General Counsel, Mass General Brigham, Boston, MA (Mr. Abrams); Department of Psychiatry and Behavioral Medicine, University of Alabama (Dr. Feldman).

Handchir Mikrochir Plast Chir 2022 Apr 13;54(2):119-125. Epub 2022 Apr 13.

Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil Bochum, Abteilung für Plastische Chirurgie und Handchirurgie, Schwerbrandverletztenzentrum, Sarkomzentrum: Prof. Dr. Marcus Lehnhardt.

Background: Patients with factitious disorders artificially generate, aggravate or feign injuries or illnesses, which can result in severe physical impairment and misuse of the healthcare system. The symptomatology is characterized by a protracted course of disease with frequent changes of practitioners and multiple invasive procedures due to anomalous, mostly chronic findings. Elaborate clinical presentations, lack of knowledge of disease characteristics and the fast-paced everyday clinical practice can lead to maintaining the disease through non-recognition or mistreatment. Read More

Epilepsy Behav Rep 2022 25;18:100506. Epub 2021 Nov 25.

Harvard Medical School, United States.

•Functional (psychogenic) symptoms exist in all specialties.•They are by definition not under voluntary control, unlike factitious disorders and malingering.•The diagnostic approach to functional symptoms varies among specialties. Read More

Cutis 2021 Dec;108(6):E23-E25

Department of Dermatology, Acıbadem Mehmet Ali Aydınlar University School of Medicine, İstanbul, Turkey.

Secretan syndrome (SS) is a recurrent or chronic form of factitious lymphedema that usually affects the dorsal aspect of the hand and is accepted as a subtype of Munchausen syndrome. Secretan syndrome usually is induced by compression of the extremity by tourniquets, ligatures, cords, or similar equipment. This unconsciously motivated and consciously produced lymphedema is an expression of underlying psychiatric disease. Read More

Acta Derm Venereol 2022 Feb 22;102:adv00654. Epub 2022 Feb 22.

Department of Dermatology, University of São Paulo, Rua Itapeva 500-3ª, 01332-000 São Paulo, SP, Brasil.

Eur J Case Rep Intern Med 2021 24;8(12):003046. Epub 2021 Dec 24.

Department of Internal Medicine, Kaweah Health Medical Center, Visalia, CA, USA.

Anion gap metabolic acidosis is a laboratory finding commonly encountered in patients with sepsis, diabetic ketoacidosis, acute kidney injury and toxic alcohol ingestion. Serum blood chemistry assessment detects this abnormality. However, this can be falsely low in situations of high triglyceride levels due to lipid interference with measurement of the bicarbonate levels and through volume displacement by these large molecules. Read More

Neurol Res Pract 2022 Jan 10;4(1). Epub 2022 Jan 10.

Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

Introduction: Treatment with CD19 chimeric antigen receptor (CAR) T cells is an innovative therapeutic approach for patients with relapsed/refractory diffuse large B cell lymphoma (r/rDLBCL) and B-lineage acute lymphoblastic leukemia (r/rALL). However, convincing therapeutic response rates can be accompanied by cytokine release syndrome (CRS) and severe neurotoxicity termed immune effector cell-associated neurotoxicity syndrome (ICANS).

Methods: Single center, prospective observational study of fifteen consecutive r/r DLBCL patients treated with Tisagenlecleucel within 1 year at Hannover Medical School. Read More

Pediatr Dermatol 2022 Jan 29;39(1):12-16. Epub 2021 Dec 29.

Psoriasis and Skin Treatment Center, Department of Dermatology, University of California, San Francisco, California, USA.

Pediatric psychodermatologic conditions encompass both primary dermatologic conditions with psychiatric comorbidities and primary psychiatric conditions with self-induced dermatologic manifestations. Detection, diagnosis, and management of primary psychiatric conditions with dermatologic manifestations are challenging due to patient-perceived stigma and lack of educational opportunities for dermatology providers. This two-part series highlights the most up-to-date evidence-based data and management techniques of some of the more common dermatoses of primary psychiatric conditions in children. Read More

Pediatr Dermatol 2022 Jan 20;39(1):17-21. Epub 2021 Dec 20.

Department of Dermatology, Psoriasis and Skin Treatment Center, University of California San Francisco, San Francisco, California, USA.

Pediatric psychodermatologic conditions encompass both primary dermatologic conditions with psychiatric comorbidities and primary psychiatric conditions with self-induced dermatologic manifestations. Detection, diagnosis, and management of primary psychiatric conditions with dermatologic manifestations are challenging due to patient-perceived stigma and lack of educational opportunities for dermatology providers. This two-part series highlights the most up-to-date evidence-based data and management techniques of some of the more common dermatoses of primary psychiatric conditions in children. Read More

BMC Psychiatry 2021 11 23;21(1):588. Epub 2021 Nov 23.

CHU Rennes, Service de Médecine Interne et Immunologie Clinique, Inserm, CIC 1414, F-35000, Rennes, France.

Background: Despite cases of factitious disorder imposed on self being documented in the literature for decades, it appears to remain an under-identified and under-diagnosed problem. The present study aimed to explore factitious disorder imposed on self in a series of French patients.

Methods: Patients 18 years old and over with factitious disorder imposed on self were retrospectively included by two independent reviewers according to DSM-5 criteria in Rennes University Hospital for the period 1995 to 2019. Read More

J Dermatol 2022 Feb 18;49(2):e75-e76. Epub 2021 Nov 18.

Department of Laboratory medicine, Tokyo Medical University, Tokyo, Japan.

Psychiatr Danub Fall 2021;33(3):371-372

Department of Psychiatry Institute of Human Behavior and Allied Sciences, Delhi, India.

Psychiatr Danub Fall 2021;33(3):368-370

Department of Psychiatry, Bakirkoy Prof Mazhar Osman Training. and Research Hospital for Psychiatry, Neurology, and Neurosurgery, 34147, Istanbul, Turkey,

Indian J Pediatr 2022 Jan 18;89(1):88. Epub 2021 Oct 18.

Division of Pediatric Endocrinology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.

Leg Med (Tokyo) 2022 Feb 25;54:101968. Epub 2021 Sep 25.

Department of Forensic Medicine, Government Medical College & Hospital, Chandigarh, India.

A factitious disorder leading to the self-infliction of highly counter-intuitive burns was diagnosed in a middle-aged female. The injuries were otherwise alleged to have been sustained by assault inflicted upon her by an unknown person. The case was diagnosed by medico-legal interpretation of injuries, in spite of a highly deceptive and concocted history by the patient and her husband. Read More

Endocr Connect 2021 Oct 25;10(11):R279-R292. Epub 2021 Oct 25.

Department of Pediatric Endocrinology and Rheumatology, Institute of Pediatrics, Karol Jonscher's Clinical Hospital, Poznan University of Medical Sciences, Poznan, Poland.

The term 'hyperthyroidism' refers to a form of thyrotoxicosis due to inappropriate high synthesis and secretion of thyroid hormone(s) by the thyroid. The leading cause of hyperthyroidism in adolescents is Graves' disease (GD); however, one should also consider other potential causes, such as toxic nodular goitre (single or multinodular), and other rare disorders leading to excessive production and release of thyroid hormones. The term 'thyrotoxicosis' refers to a clinical state resulting from inappropriate high thyroid hormone action in tissues, generally due to inappropriate high tissue thyroid hormone levels. Read More

Am J Med Sci 2021 11 9;362(5):516-521. Epub 2020 Nov 9.

Division of Gastroenterology and Hepatology, Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA. Electronic address:

Factitious gastrointestinal bleeding (GIB) is a manifestation of factitious disorder (FD) wherein patients feign GIB in the absence of external gain. As it can be a challenging diagnosis to make, factitious GIB often leads to multiple tests, exposure to contrast agents and radiation, invasive endoscopic and surgical procedures, an increased risk of iatrogenic complications, and increased healthcare costs. Patients who feign GIB often demonstrate characteristic behaviors that may go unnoticed unless they are explicitly addressed. Read More

Encephale 2021 Dec 16;47(6):596-604. Epub 2021 Sep 16.

Maison de Solenn, hôpital Cochin, 75014 Paris, France; PCPP, université de Paris, 92100 Boulogne-Billancourt, France; Inserm, CESP, Team DevPsy, UVSQ, université Paris-Saclay, 94807 Villejuif, France.

Objectives: Body expression of mental disorders is common in adolescence. Only two literature reviews over the last five years have been identified about somatoform disorders in children., The present article provides a systematic review of articles in English, which concern "Somatic Symptom and Related Disorders" according to the DSM-5 (Diagnostic and Statistical Manual - 5th Edition) among adolescents. Read More

Br J Haematol 2021 11 12;195(3):417-428. Epub 2021 Sep 12.

CHU de Lille, INSERM U1286, Univ Lille, Lille, France.

Allogeneic haematopoietic-cell transplantation (allo-HCT) is a potentially curative therapy for high-risk myelodysplastic syndrome (MDS). Reduced-intensity conditioning (RIC) is usually associated with lower non-relapse mortality (NRM), higher relapse rate and similar overall-survival (OS) as myeloablative-conditioning (MAC). Fludarabine/treosulfan (FT) is a reduced-toxicity regimen with intense anti-leukaemia activity and a favourable toxicity profile. Read More

Int Psychogeriatr 2021 08;33(8):751-754

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.

Neurochem Res 2021 Dec 18;46(12):3273-3285. Epub 2021 Aug 18.

Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, 75270, Karachi, Pakistan.

Depressive state adversely affects the memory functions, especially in the geriatric population. The initial stage of memory deficits associated with depression is particularly called as pseudodementia. It is the starting point of memory disturbance before dementia. Read More

J Neuropsychiatry Clin Neurosci 2021 16;33(4):356-364. Epub 2021 Aug 16.

Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tenn. (Wilson, Andrews); Center for Critical Illness, Brain Dysfunction, and Survivorship, Vanderbilt University Medical Center (Wilson, Andrews, Ely); University of Rochester Medical Center, Rochester, N.Y. (Ainsworth, Oldham); Oregon Health and Science University, Portland, Ore. (Roy); Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center (Ely); Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center (Ely); and Veteran's Affairs Tennessee Valley, Geriatrics Research, Education and Clinical Center, Nashville, Tenn. (Wilson, Ely).

Objective: The phenotypes of several psychiatric conditions can very closely resemble delirium; the authors describe such presentations as pseudodelirium. However, because the clinical management of these conditions differs markedly from that of delirium, prompt differentiation is essential. The authors provide an educational review to assist clinicians in identifying and managing psychiatric conditions that may be especially challenging to differentiate from delirium. Read More

Dermatol Online J 2021 Jun 15;27(6). Epub 2021 Jun 15.

Department of Dermatology, Mayo Clinic, Jacksonville, FL.

A 40-year-old previously healthy, non-atopic woman was referred for evaluation of a possible immunodeficiency disorder in the setting of an unusual erosive cheilitis and history of recurrent methicillin-resistant Staphylococcus aureus (MRSA) infection. Extensive work-up was non-diagnostic, including screening for immunologic disorders. She had failed multiple therapeutic modalities, including corticosteroid and immunosuppressive therapy. Read More

Prim Care Companion CNS Disord 2021 Aug 5;23(4). Epub 2021 Aug 5.

Department of Dermatology, Venereology, and Leprosy, RG Kar Medical College and Hospital, Kolkata, West Bengal, India.

Psychogenic purpura is a rare psychocutaneous entity characterized by painful atraumatic, ecchymotic, and purpuric lesions that commonly occur in young women. The objective of this study is to describe the clinical presentation, psychiatric profile, and response to therapy (pharmacologic and psychotherapeutic) in patients with psychogenic purpura.

Twenty-three patients, referred from various clinical departments with unexplained purpura or ecchymotic lesions, were assessed in the department of psychiatry of a tertiary care institute in eastern India over a period of 3 years (May 1, 2017, to April 30, 2020). Read More

Neurol Sci 2021 Oct 4;42(10):4073-4083. Epub 2021 Aug 4.

Department of Neuroscience, Imaging, and Clinical Sciences, "G. D'Annunzio University" of Chieti-Pescara 66100, Chieti, Italy.

Factitious disorder is classified as one of the five aspects of somatic symptom disorders. The fundamental element of factitious disorder is deception, i.e. Read More

Aust N Z J Psychiatry 2022 05 4;56(5):572-573. Epub 2021 Aug 4.

Department of Dermatology, The Alfred Hospital, Melbourne, VIC, Australia.