41,721 results match your criteria Gallbladder Volvulus


Usefulness of noncontrast MRI in differentiation between gallbladder carcinoma and benign conditions manifesting as focal mild wall thickening.

Clin Imaging 2018 Dec 4;54:63-70. Epub 2018 Dec 4.

Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: Magnetic resonance imaging (MRI) is a reliable imaging tool for evaluating gallbladder carcinoma, but it is costly and time-consuming.

Purpose: To compare noncontrast MRI with multidetector row CT (MDCT) and gadoxetic acid-enhanced whole MRI in distinguishing gallbladder carcinoma from benign disease.

Materials And Methods: 101 patients (36 with gallbladder carcinoma and 65 with benign disease) with mild focal gallbladder wall thickening were included. Read More

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December 2018

Ultrasound Assessment of Hepatobiliary and Splenic Changes in Patients With Dengue and Warning Signs During the Acute and Recovery Phases.

J Ultrasound Med 2018 Dec 14. Epub 2018 Dec 14.

Infectious Diseases, Federal University of Triângulo Mineiro, Uberaba, Brazil.

Objectives: To evaluate whether abdominal ultrasound (US) with a gallbladder (GB) contractility study or motor function test can be used as a diagnostic tool in patients with dengue and warning signs in acute and recovery phases.

Methods: Fifty-one individuals in the acute phase of dengue presenting with warning signs (dengue group) and 49 healthy individuals without a history of dengue or hepatobiliary disease (control group) were studied with abdominal US and a GB contractility study.

Results: Statistical differences in US measurements of the liver (right lobe, P = . Read More

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December 2018

Effective method of gallbladder retraction for single-incision laparoscopic cholecystectomy.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Introduction: Recently, single-incision laparoscopic cholecystectomy has been accepted as an alternative to conventional laparoscopic cholecystectomy. The aim of this study was to retrospectively evaluate the safety and feasibility of unique gallbladder retraction methods using an ENDOLOOP® (Ethicon, Tokyo, Japan) and Lapaherclosure™ (Hakko Medical, Tokyo, Japan).

Materials And Surgical Technique: From May 2013 to April 2015, 77 patients underwent single-incision laparoscopic cholecystectomy with this retraction technique. Read More

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December 2018

Combination of electrohydraulic lithotripsy and laparoscopy for gallbladder access in type III Mirizzi syndrome.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Division of Surgery, Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan.

Introduction: A 50-year-old Japanese man presented with obstructive jaundice. We performed endoscopic retrograde biliary drainage before biliary decompression. CT showed a thickened gallbladder wall with low-density areas and a 35-mm gallstone; the stone was impacted in the gallbladder neck and cystic duct. Read More

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December 2018

[Effects of glucagon-like peptides on gallbladder motility].

Ugeskr Laeger 2018 Dec;180(50)

As cases of gallbladder-related adverse events have been reported in patients treated with glucagon-like peptide (GLP)-1 receptor agonists and GLP-2 receptor agonists, studies have investigated the effects of these hormones on the enterohepatic circulation of bile acids and gallbladder motility. Results suggest, that bile acids and GLP-2 counteract postprandial cholecystokinin-mediated gallbladder contraction, while GLP-1 may delay gallbladder refilling. This provides important information on the effect and safety of drugs based on GLP-1 and GLP-2, respectively. Read More

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December 2018

Hemorrhage from metastasis of a 5-mm renal cell carcinoma lesion to the gallbladder detected by contrast-enhanced endoscopic ultrasonography.

Dig Liver Dis 2018 Nov 22. Epub 2018 Nov 22.

Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.

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November 2018

First in-human radiation dosimetry of the gastrin-releasing peptide (GRP) receptor antagonist Ga-NODAGA-MJ9.

EJNMMI Res 2018 Dec 12;8(1):108. Epub 2018 Dec 12.

Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland.

Background: Gastrin-releasing peptide receptor antagonists have promise in theranostics of several highly incident tumours, including prostate and breast. This study presents the first human dosimetry of Ga-NODAGA-MJ9 in the first five consecutive patients with recurrent prostate cancer included in a dual-tracer positron emission tomography (PET) protocol. Five male patients with biochemical relapse of prostate adenocarcinoma underwent four whole-body time-of-flight PET/CT scans within 2 h after tracer injection. Read More

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December 2018

Hemocholecyst related to cholecystitis secondary to pseudoaneurysm mimicking gallbladder cancer.

Turk J Gastroenterol 2018 Dec 12. Epub 2018 Dec 12.

Department of Surgery, Show Chwan Memorial Hospital, Changhua, Taiwan.

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December 2018

Single-stranded DNA binding protein 2 expression is associated with patient survival in hepatocellular carcinoma.

BMC Cancer 2018 Dec 12;18(1):1244. Epub 2018 Dec 12.

Departments of Surgery, College of Medicine, Hanyang University222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea.

Background: SSBP2, single-stranded DNA binding protein 2, is a subunit of the ssDNA-binding complex that is involved in the maintenance of genome stability. The majority of previous studies have suggested a tumor-suppressive role of SSBP2, which is silenced by promoter hypermethylation in several human malignancies, such as hematologic malignancies, prostate cancer, esophageal squamous cell carcinoma, ovarian cancer, and gallbladder cancer. However, an oncogenic role of SSBP2 has been suggested in glioblastoma patients. Read More

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December 2018

Intracholecystic Papillary-Tubular Neoplasm of the Gallbladder.

Mayo Clin Proc 2018 Dec;93(12):1883-1884

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

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December 2018

Occult Gallbladder Carcinoma Presenting as a Primary Ovarian Tumour: a Case Report and Review of Literature.

Indian J Surg Oncol 2018 Dec 20;9(4):618-621. Epub 2018 Jul 20.

1Department of Obstetrics and Gynaecology, K.S. Hegde Medical Academy, Mangalore, 575018 India.

The ovary is a common site of metastasis from various organs. However, little is known about gallbladder carcinoma metastasising to the ovaries and presenting as a primary ovarian tumour. We report a case of a metastatic gallbladder carcinoma which mimicked a primary ovarian tumour in a 31-year-old woman who presented with menstrual symptoms and an ovarian mass without obvious signs and symptoms related to gallbladder carcinoma. Read More

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December 2018

Safety and Efficacy of Low-Dose Single-Agent Capecitabine in Inoperable Gallbladder Cancer with Jaundice Post-Single-System Single-Catheter External Biliary Drainage: a Pilot Study from a Highly Endemic Area.

Indian J Surg Oncol 2018 Dec 31;9(4):530-537. Epub 2018 Jul 31.

1Department of General Surgery, King George's Medical University, Lucknow, UP India.

Gallbladder cancer (CaGB) in the subcontinent belongs to low socioeconomic status, and at the time of diagnosis, a large number is unresectable or inoperable so the palliative treatment remains the only option. In the present study, attempt was made to see the effect and safety profile of single-agent oral capecitabine in inoperable CaGB in presence of low levels of jaundice post-single-catheter transhepatic external biliary drainage. In  = 35 of inoperable jaundiced CaGB, post-biliary drainage capecitabine in low dose was started when their total bilirubin levels fell to 10 mg% or below. Read More

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December 2018

A case report on the gallbladder fluke, (Trematoda: Dicrocoeliidae), in stray cats () in Beni-Suef, Egypt.

J Parasit Dis 2018 Dec 13;42(4):646-650. Epub 2018 Oct 13.

1Department of Parasitology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511 Egypt.

Scarce literature studying parasites, particularly helminths, of gallbladder of cats in Egypt are available. Stray cats () are widespread in Beni-Suef, Egypt. Therefore, a total of 62 stray cats were necropsied and parasitologically examined. Read More

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December 2018

Adjuvant Therapy for Biliary Tract Cancers.

J Oncol Pract 2018 Dec;14(12):701-708

South East Cancer Center, University Hospital Waterford, Waterford, Ireland; and Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.

Biliary tract cancers, including gallbladder cancer, intrahepatic, perihilar, and distal cholangiocarcinomas, although anatomically contiguous, represent a heterogeneous group of cancers with extensive biologic and genetic diversity. With early disease, surgical resection is the preferred option for all subtypes; however, relapse rates remain high, and survival outcomes are poor. Data to guide the use of adjuvant therapy have been limited to retrospective series, population-based studies, and meta-analyses, all with their associated limitations. Read More

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December 2018
1 Read

Thirty days are inadequate for assessing readmission following complex hepatopancreatobiliary procedures.

Surg Endosc 2018 Dec 10. Epub 2018 Dec 10.

Division of Bariatric, Foregut and Advanced Gastrointestinal Surgery, Department of Surgery, Stony Brook University Medical Center, 100 Nichols Road, HSC T18-040, Stony Brook, 11794, NY, USA.

Introduction: Early readmissions (30 days) have been used as a measure of health care quality. The purpose of our study was to evaluate patterns of readmission for a longer period (up to 2 years) following Hepatopancreatobiliary (HPB) surgery in the state of New York.

Methods: The State Planning and Research Cooperative System database was utilized to identify patients undergoing complex HPB procedures between 2010 and 2012. Read More

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December 2018
1 Read

Application of contrast enhanced ultrasound in gallbladder lesion: is it helpful to improve the diagnostic capabilities?

Med Ultrason 2018 Dec;20(4):420-426

Department of ultrasound, Drumtower Hospital, Medical College of Nanjing University, Nanjing, China.

The aim of this study is to evaluate if contrast enhanced ultrasound (CEUS) can improve the differential diagnostic performance of gallbladder (GB) lesions.

Materials And Methods: Forty-nine patients (18 men, 31 women; mean age, 54.8±14. Read More

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December 2018

Differential diagnosis of gallbladder ascariasis debris: the added value of contrast enhanced ultrasound with high frequency transducer.

Med Ultrason 2018 Dec;20(4):413-419

Medizinische Klinik 2, Caritas-Krankenhaus Bad Mergentheim, Bad Mergentheim, Germany.

Ascariasis debris of the gallbladder is a very rare incidental or symptomatic presentation. Ascaris debris has a pseudotumorous appearance and may be confused with neoplasia. The aim of the current retrospective study is to investigate the value of contrast enhanced ultrasound (CEUS) for the differential diagnosis of ascariasis debris and neoplasia of the gallbladder. Read More

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December 2018

A Rare Case of Pylephlebitis as a Complication of Cholecystocolonic Fistula.

Case Rep Surg 2018 4;2018:3931674. Epub 2018 Nov 4.

Department of Surgery, Chugoku Rosai Hospital, 1-5-1 Hirotagaya, Kure, Hiroshima 737-0193, Japan.

Pylephlebitis is defined as a septic thrombophlebitis of the portal vein and its tributaries that is associated with multiple suppurative abdominal infections. We report a case of pylephlebitis associated with a cholecystocolonic fistula (CCF). A 41-year-old man presented with upper abdominal pain and anorexia for 1 month. Read More

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November 2018
1 Read

[Comparative analysis of side-by-side antegrade stenting and Y-biliary stenting for malignant biliary stricture].

Khirurgiia (Mosk) 2018 (11):20-23

Botkin Municipal Clinical Hospital, Moscow, Russia.

In the time period from 2009 to 2017 in Botkin Hospital (Moscow) bilateral biliary stenting was performed in 43 patients with malignant common hepatic duct stricture. Patients were divided into 2 statistically homogeneous groups: 'side-by-side' stenting in 28 patients and percutaneous 'Y'-biliary stent placement in 15 patients. The causes of malignant obstruction were as follows: in the 1 group 13 (46. Read More

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January 2018
1 Read

[Endogenic antimicrobial peptides and cytokines in calculous cholecystitis].

Khirurgiia (Mosk) 2018 (10):51-54

Azerbaijan Medical University, Baku, Azerbaijan.

Aim: To analyze concentration of some antimicrobial peptides and cytotoxins in acute calculous cholecystitis regarding gallbladder inflammation grade.

Material And Methods: There were 69 patients with catarrhal (29), phlegmonous (24) inflammation and gangrenous phlegmon (19). Some antimicrobial peptides (HNP-α, BPI, endotoxin, neutrophil elastase, lactoferritin, hepcidin) and cytokines (TNF-α, IL-6, 8, 10) in blood serum as well as hepcidin, TNF-α and IL-6 in hepatic biopsy samples were assessed. Read More

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January 2018

Comparison of Laparoscopic and Open Approach in Treating Gallbladder Cancer.

J Surg Res 2019 Feb 16;234:269-276. Epub 2018 Oct 16.

Changzhou First People's Hospital, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China. Electronic address:

Background: Preliminary study on the feasibility and efficacy of laparoscopic cholecystectomy and radical cholecystectomy in stage Tis-T3 gallbladder cancer (GBC).

Methods: Retrospective analysis of the clinical data of 102 patients with GBC from August 2008 to August 2017 in the Department of Hepatopancreatobiliary Surgery at the Third Affiliated Hospital of Soochow University. The clinical and pathological data of laparoscopic surgery and open surgery were compared. Read More

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February 2019
2 Reads

Accuracy of Right Upper Quadrant Ultrasound in Estimating Gallbladder Wall Thickness.

Surg Laparosc Endosc Percutan Tech 2018 Dec 4. Epub 2018 Dec 4.

Departments of Surgery.

Objective: Ultrasound (US) evaluation of biliary pathology can be influenced by a variety of factors. This study examines the effect of patient specific factors on the accuracy of sonographic evaluation of gallbladder wall thickness (GBW).

Methods: We performed a retrospective review of all patients who underwent cholecystectomy at a single institution from November 2012 to October 2015. Read More

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December 2018
2 Reads

Incidental Hepatic Tissue Obtained via Routine Cholecystectomy.

Int J Surg Pathol 2018 Dec 6:1066896918817374. Epub 2018 Dec 6.

2 University of California, Irvine, CA, USA.

Background: The hepatic tissue that may occupy specimens from routine cholecystectomies has yet to be studied. Our objectives were to determine the prevalence of hepatic tissue obtained at routine cholecystectomy, to determine whether such hepatic tissue can histologically withstand technical artifacts commonly associated with cholecystectomy, and to determine whether examining such hepatic tissue has diagnostic utility.

Materials And Methods: We retrospectively reviewed 50 specimens from routine cholecystectomies that were performed by surgeons who lacked knowledge of our study. Read More

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December 2018
2 Reads

Diagnostic laparoscopy to investigate unexplained lactic acidosis in critically ill patients - A descriptive single centre cohort study.

Ann Med Surg (Lond) 2018 Dec 13;36:231-234. Epub 2018 Nov 13.

Department of Surgery, University Hospital Hairmyres, NHS Lanarkshire, East Kilbride, G75 8RG, Scotland, UK.

Introduction: Unexplained lactic acidosis (LA) in a critically ill patient often prompts investigations to rule out any reversible intra-abdominal cause. Equivocal results can lead to an emergency laparotomy (EL) with subsequent high morbidity and mortality rates. Our objective was to determine the clinical impact of urgent diagnostic laparoscopy (UDL) in such patients. Read More

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December 2018
2 Reads

High-Risk Comorbidity Combinations in Older Patients Undergoing Emergency General Surgery.

J Am Geriatr Soc 2018 Dec 2. Epub 2018 Dec 2.

Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio.

Background/objectives: Over a million older patients in the United States are admitted yearly for emergency general surgery (EGS) conditions. Seven procedure types dominate: colon, small bowel, gallbladder, ulcer disease, adhesiolysis, appendix, and laparotomy operations. A higher comorbidity burden is known to increase mortality in this population, but the impact of specific comorbidity combinations is unknown. Read More

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December 2018
6 Reads

Intracholecystic papillary-tubular neoplasm of the gallbladder originating in the cystic duct with extensive intraepithelial progress in the common bile duct.

Clin J Gastroenterol 2018 Nov 30. Epub 2018 Nov 30.

Department of Gastroenterology, Sendai City Medical Center, 5-22-1, Tsurugaya, Miyagino-ku, Sendai, Miyagi, Japan.

A 59-year-old man with anorexia who had a history of cholecystectomy was referred to our hospital. Imaging examinations revealed a contrast-enhanced tumor in the residual cystic duct and a part of the common bile duct. Endoscopic retrograde cholangiopancreatography and peroral-cholangioscopy showed a papillary tumor with movement and a change in the shape. Read More

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November 2018
2 Reads

A case of hemobilia secondary to cancer of the gallbladder confirmed by cholangioscopy and treated with a fully covered self-expanding metal stent.

VideoGIE 2018 Dec 4;3(12):381-383. Epub 2018 Oct 4.

Department of Gastroenterology and Hepatology, St George Hospital, Kogarah, Australia.

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December 2018
2 Reads

Cholangioscopy in the digital era.

Transl Gastroenterol Hepatol 2018 29;3:82. Epub 2018 Oct 29.

Division of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, FL, USA.

Cholangioscopy allows direct visualization and subsequent therapeutic maneuvers of the biliary ductal system. With advances in endoscopic and imaging technology, cholangioscopy has become an important modality for the diagnosis of indeterminate biliary strictures and an essential therapeutic tool for difficult to remove biliary stones. Enhanced imaging and operability of the latest generation cholangioscopes have further expanded their clinical applications to include ductal tumor ablation, gallbladder drainage, access to difficult to reach branches of the biliary tree, and biliary foreign body manipulation. Read More

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October 2018
3 Reads

Double cholecystectomy in case of accessory gallbladder: Not as easy as two cholecystectomies.

Hepatobiliary Pancreat Dis Int 2018 Nov 24. Epub 2018 Nov 24.

Department of General Surgery and Liver Transplantation, Hospices Civils de Lyon, Croix-Rousse University Hospital, Lyon, France; Ecole Doctorale EDISS 205, Université Lyon 1, EMR 3738, Lyon, France.

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November 2018
2 Reads

Endogenous endophthalmitis due to Klebsiella pneumoniae from an infected gallbladder.

Can J Ophthalmol 2018 Dec 16;53(6):e258-e260. Epub 2018 Mar 16.

University of Alberta, Edmonton, Alta. Electronic address:

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December 2018
3 Reads

Modifications to Expose Porta Hepatis for Laparoscopic Portoenterostomy Easier in Biliary Atresia.

J Surg Res 2019 Jan 10;233:368-375. Epub 2018 Sep 10.

Department of General surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu, China.

Background: Laparoscopic Kasai portoenterostomy (LKPE) is generally regarded to have a poorer outcome for surgical treatment of uncorrectable biliary atresia. We herein described our initial experience of some modifications to make LKPE easier in the treatment of type III biliary atresia (BA).

Methods: During the period July 2012-October 2016, a total of 25 infants with type III BA were treated with a modified LKPE technique. Read More

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January 2019
2 Reads

Gallbladder Metastasis From Conjunctival Melanoma.

Clin Nucl Med 2018 Dec 3. Epub 2018 Dec 3.

From the Department of Nuclear Medicine, Institut Curie, PSL Research University, Paris, France.

Malignant conjunctival melanoma is a rare tumor. A 46-year-old woman with a history of locally recurrent left conjunctival melanoma was followed by F-FDG PET/CT. Four years after the local recurrence treated by orbital exenteration, the follow-up PET/CT scan showed an incidental intense FDG uptake mass infiltrating the gallbladder associated with a low uptake of an infracentimetric pulmonary nodule. Read More

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December 2018
2 Reads

Identification of a Small Molecule Anti-biofilm Agent Against .

Front Microbiol 2018 20;9:2804. Epub 2018 Nov 20.

Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Ohio State University, Columbus, OH, United States.

Biofilm formation is a common strategy utilized by bacterial pathogens to establish persistence in a host niche. serovar Typhi, the etiological agent of Typhoid fever, relies on biofilm formation in the gallbladder to chronically colonize asymptomatic carriers, allowing for transmission to uninfected individuals. serovar Typhimurium utilizes biofilms to achieve persistence in human and animal hosts, an issue of both clinical and agricultural importance. Read More

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November 2018
1 Read

First-in-human phase 1 study of novel dUTPase inhibitor TAS-114 in combination with S-1 in Japanese patients with advanced solid tumors.

Invest New Drugs 2018 Dec 4. Epub 2018 Dec 4.

Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.

Background This first-in-human phase 1 study assessed the safety of TAS-114, a novel deoxyuridine triphosphatase inhibitor, combined with S-1 to determine its maximum tolerated dose (MTD) and recommended dose (RD). Methods In this dose-escalation study with a 3 + 3 design, TAS-114 and S-1 were concurrently administered orally under fasting conditions at 5-240 mg/m and 30-36 mg/m, respectively, in patients with advanced solid tumors. Safety, efficacy, and pharmacokinetics (PK) were evaluated. Read More

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December 2018
1 Read

Gallbladder varices in a pediatric patient after roux-en-Y gastric bypass.

J Pediatr Surg 2018 Dec 25;53(12):2511-2513. Epub 2018 Aug 25.

Department of Pediatric Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.

This is a case with associated radiologic images for a pediatric patient who developed portomesenteric and splenic vein thrombosis (PMSVT) after Roux-en-Y gastric bypass with subsequent development of portal cavernoma and gallbladder varices (GBV). This case highlights both the importance of post-operative prophylactic anti-coagulation after gastric bypass and detailed imaging following a diagnosis of PMSVT. This case is relevant for pediatric surgeons as they are performing this operation more frequently with the increase in pediatric obesity. Read More

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December 2018
3 Reads

National Failure of Surgical Staging for T1b Gallbladder Cancer.

Ann Surg Oncol 2018 Nov 29. Epub 2018 Nov 29.

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Michael E. DeBakey VA Medical Center, Houston, TX, USA.

Background: Current guidelines recommend radical cholecystectomy with regional lymphadenectomy (RC-RL) for patients with T1b gallbladder cancer (GBC). However, the extent to which these guidelines are followed is unclear. This study aimed to evaluate current surgical practices for T1b GBC and their implications for overall management strategies and associated outcomes. Read More

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November 2018
4 Reads

A "reappearance" of gallbladder in a liver transplant recipient.

Hepatobiliary Surg Nutr 2018 Oct;7(5):412-413

Department of General and Liver/Pancreas Transplant Surgery, University of Montpellier-College of Medicine, Hôpital Saint Eloi, Montpellier, France.

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October 2018
3 Reads

Neoplastic Meningitis: A Study from a Tertiary Care Hospital from Coastal India.

J Cytol 2018 Oct-Dec;35(4):255-259

Department of Cellular Pathology, Leighton Hospital, Crewe, Cheshire, United Kingdom.

Introduction: Neoplastic involvement of cerebrospinal fluid (CSF) secondary to known or unknown primaries elsewhere is a poor prognostic factor and is equivalent to stage IV disease.

Aim: The aim of the study is to analyse the cytological features of neoplastic meningitis in a tertiary care center.

Materials And Methods: A retrospective study of 400 consecutive CSF samples was done in the cytology laboratory of our hospital. Read More

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December 2018
2 Reads

EUS-guided gallbladder polyp resection: A new method for treatment of gallbladder polyps.

Hepatobiliary Pancreat Dis Int 2018 Nov 22. Epub 2018 Nov 22.

Department of Gastroenterology and Hepatology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China. Electronic address:

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November 2018
3 Reads

EBV as a potential risk factor for hepatobiliary system cancer: A meta-analysis with 918 cases.

Pathol Res Pract 2018 Nov 2. Epub 2018 Nov 2.

Department of General Surgery, The Second Affiliated Hospital of Guangxi Medical University, NO.166. DaxueXi Rd, Nanning, Guangxi Zhuang Autonomous Region, 530021, PR China. Electronic address:

Objectives: Hepatobiliary system cancer, which includes hepatocellular carcinoma (HCC), cholangiocarcinoma, and gallbladder carcinoma, has an increase of incidence and mortality due to various risk factors. Epstein-Barr virus (EBV) is associated with various types of lymphomas and carcinomas, which is also acknowledged as the first-discovered human tumor virus. Despite this, there is no systematic analysis about the relationship between the infection of EBV and hepatobiliary system cancer. Read More

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November 2018
1 Read

MiR-1-5p is down-regulated in gallbladder carcinoma and suppresses cell proliferation, migration and invasion by targeting Notch2.

Pathol Res Pract 2018 Oct 22. Epub 2018 Oct 22.

Emergency Trauma Surgery, BinZhou Medical University Hospital, Binzhou, Shandong, 256600, China. Electronic address:

Background: Numerous studies have demonstrated that aberrant microRNAs (miRNAs) are involved in tumorigenesis and tumor progression. Nevertheless, the precise role of miR-1-5p in gallbladder carcinoma cell growth and metastasis remains not fully revealed.

Material And Methods: The levels of miR-1-5p were detected in gallbladder carcinoma tissues and cell lines using qRT-PCR method. Read More

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October 2018
4 Reads

Strategy for discriminating cholesterol and premalignancy in polypoid lesions of the gallbladder: a single-centre, retrospective cohort study.

ANZ J Surg 2018 Nov 29. Epub 2018 Nov 29.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Background: The present study aimed to assess the risk factors of cholesterol and premalignancy in polypoid lesions of the gallbladder (PLGs) and to establish an appropriate treatment strategy.

Methods: Data from patients who underwent cholecystectomy at the First Affiliated Hospital, School of Medicine, Zhejiang University, between January 2011 and July 2017, were collected retrospectively.

Results: A total of 1561 patients were included in the present study. Read More

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November 2018
2 Reads

Radiofrequency ablation of liver cancers adjacent to the gallbladder without gallbladder isolation under contrast-enhanced ultrasound monitoring: a preliminary study.

Int J Hyperthermia 2018 Nov 29:1-6. Epub 2018 Nov 29.

a Department of Medical Ultrasonics, Guangdong Key Laboratory of Liver Disease Research , The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.

Purpose: The purpose of this study was to investigate the feasibility, safety and efficacy of intra-procedural contrast-enhanced ultrasound (CEUS) monitoring of the radiofrequency ablation (RFA) of liver cancers adjacent to gallbladder (GB) without GB isolation.

Materials And Methods: From May 2016 to July 2017, patients with liver cancers adjacent to GB (≤10 mm) who intended to undergo ultrasound-guided RFA without GB isolation in our hospital were prospectively enrolled. During the RFA procedures, CEUS was employed to evaluate the therapeutic response and the perfusion of the intact GB wall. Read More

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November 2018
3 Reads

Importance of routine histopathological examination of a gallbladder surgical specimen: Unexpected gallbladder cancer.

J Cancer Res Ther 2018 Oct-Dec;14(6):1325-1329

Department of General Surgery, Faculty of Medicine, Adıyaman University, Adıyaman, Turkey.

Introduction: Cholecystectomy performed for benign diseases of the gallbladder is important for the diagnosis of gallbladder cancer. This is done by pathological examination of the removed specimens for patients with no detected or suspected complications before surgery. Although some centers undertake selective approaches for histopathological examination of gallbladder specimens, many centers perform this examination routinely. Read More

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November 2018
4 Reads

A Gallbladder-Based Enterohepatic Circulation Model for Pharmacokinetic Studies.

Eur J Drug Metab Pharmacokinet 2018 Nov 28. Epub 2018 Nov 28.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.

Background And Objectives: Strategies for modeling the enterohepatic circulation (EHC) process reported in the literature vary; however, gallbladder-based models currently provide the best physiological representation of the process. Regardless, the addition of a gallbladder to the model does not fully depict the physiology of EHC. A more physiological gallbladder-based EHC model is needed. Read More

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November 2018
9 Reads

The "honeycomb" gallbladder.

Abdom Radiol (NY) 2018 Nov 28. Epub 2018 Nov 28.

Department of Radiology, Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC, 27157, USA.

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November 2018
2 Reads

Stepwise evaluation of liver sectors and liver segments by endoscopic ultrasound.

World J Gastrointest Endosc 2018 Nov;10(11):326-339

Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute, Lucknow 226014, Uttar Pradesh, India.

The liver has eight segments, which are referred to by numbers or by names. The numbering of the segments is done in a counterclockwise manner with the liver being viewed from the inferior surface, starting from Segment I (the caudate lobe). Standard anatomical description of the liver segments is available by computed tomographic scan and ultrasonography. Read More

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November 2018
3 Reads

Acute acalculous cholecystitis in children.

World J Gastroenterol 2018 Nov;24(43):4870-4879

Department of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.

Acute acalculous cholecystitis (AAC) is the inflammatory disease of the gallbladder in the absence of gallstones. AAC is estimated to represent at least 50% to 70% of all cases of acute cholecystitis during childhood. Although this pathology was originally described in critically ill or post-surgical patients, most pediatric cases have been observed during several infectious diseases. Read More

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November 2018
5 Reads

A 52 Years Old Male Presented With Acute Kidney Injury with Hepatitis after Taking Fish Gallbladder.

Authors:
O F Miah F A Dowel

Mymensingh Med J 2018 Oct;27(4):866-868

Dr Mohammad Omar Faruque Miah, Senior Clinical Pathologist, Department of Pathology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh.

A 52 years old male was admitted at National Institute of Kidney Diseases & Urology, Dhaka, Bangladesh on 16th September 2016 with the history of oliguria, nausea, vomiting & swelling of both legs following consumption of rohu fish gall bladder for the permanent remedy of recurrent abdominal discomfort. He was admitted and received antiemetic, proton pump inhibitor. He had azotemia & underwent urgent haemodialysis (HD). Read More

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October 2018
1 Read