1,574 results match your criteria Gallbladder Carcinoma Imaging

Robotic Distal Pancreatectomy and Splenectomy for an Intrapancreatic Hepatocellular Carcinoma: A Case Report and Review of the Literature.

J Pancreat Cancer 2020 27;6(1):96-101. Epub 2020 Oct 27.

Department of Surgery, NorthShore University HealthSystem, Evanston, Illinois, USA.

Liver parenchyma that resides outside of the normal hepatic confines is defined as accessory liver if in communication with the native biliary tree, or ectopic liver (EL) if it is not. EL can develop in a variety of tissues, including but not limited to the gallbladder, the hepatic ligaments, the pancreas, and retroperitoneum. EL has an increased propensity for malignant degeneration resulting in hepatocellular carcinoma (HCC). Read More

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October 2020

LncRNA TTN-AS1 acts as a tumor promoter in gallbladder carcinoma by regulating miR-107/HMGA1 axis.

World J Surg Oncol 2021 Jun 5;19(1):163. Epub 2021 Jun 5.

Department of Pathology, Qingdao Municipal Hospital, No. 5 Donghai Middle Road, Shandong Province, Qingdao, 266071, China.

Background: The incidence of gallbladder carcinoma (GBM) in China has increased in recent years. Here, the functional mechanism of lncRNA TTN-AS1 in GBC was preliminary elucidated.

Methods: The expression levels of lncRNA TTN-AS1, miR-107, and HMGA1 in tissues and cell lines were assessed by RT-qPCR. Read More

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Cystic artery pseudoaneurysm due to carcinoma of the gallbladder.

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

Surgery, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, Puducherry, India.

A 52-year-old man, with known case of hypertension and stroke, presented to us with an upper gastrointestinal bleed and abdominal pain. Ultrasonography of the abdomen showed haematoma within the gallbladder (GB), and Doppler ultrasound was suggestive of an aneurysm arising from the cystic artery (CA). CT of the abdomen showed a well-enhancing thick-walled GB suggestive of malignancy. Read More

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Percutaneous Cryoablation of Liver Tumors: Initial Experience from a Tertiary Care Center in India.

J Clin Exp Hepatol 2021 May-Jun;11(3):305-311. Epub 2020 Oct 19.

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Percutaneous ablation is an important part of management strategy for liver tumors. While radiofrequency ablation and microwave ablation are the most widely used ablative techniques, cryoablation (CA) has several technical advantages but has been underused till recently. In this study, we report the initial experience with percutaneous CA of liver tumors. Read More

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October 2020

Clear-Cell Adenocarcinoma of the Gallbladder with Alpha-Fetoprotein Production: A Case Report and Review of the Literature.

Gastrointest Tumors 2021 Apr 27;8(2):52-57. Epub 2021 Jan 27.

Department of Urology, Indraprashtha Apollo Hospital, Delhi, India.

Gallbladder tumors are the fifth most common cancers of the gastrointestinal tract with poor prognosis and low survival. The most common type is adenocarcinoma of which the clear cell type is an unusual histologic variant with alpha-fetoprotein (AFP)-producing gallbladder carcinoma, reported extremely rarely, which makes the index case an uncommon entity. AFP secretion by gallbladder carcinomas may occur given the similar embryological origin of liver and gallbladder. Read More

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Rare Mixed Adenoneuroendocrine Carcinoma of the Gallbladder: Case Report and Review of Literature.

Am J Case Rep 2021 May 4;22:e929511. Epub 2021 May 4.

General Surgery Division, Hospital das Clínicas at Federal University of Pernambuco (HC/UFPE), Recife, PE, Brazil.

BACKGROUND Mixed adenoneuroendocrine carcinoma of the gallbladder (gMANEC) is an extremely rare cancer. Most of the cases are reported in Asia, North America, and Europe, with no cases reported in Latin America; this is the first report for this region, and the 24th case reported worldwide. CASE REPORT A 68-year-old woman was referred to our department due to asthenia and moderate abdominal pain in the right upper quadrant for 6 months, with imaging examinations showing a solid heterogeneous expansive lesion in gallbladder topography and segment IV of the liver. Read More

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How Can We Manage Gallbladder Lesions by Transabdominal Ultrasound?

Shinji Okaniwa

Diagnostics (Basel) 2021 Apr 26;11(5). Epub 2021 Apr 26.

Department of Gastroenterology, Iida Municipal Hospital 1, Iida, Nagano 395-8502, Japan.

The most important role of ultrasound (US) in the management of gallbladder (GB) lesions is to detect lesions earlier and differentiate them from GB carcinoma (GBC). To avoid overlooking lesions, postural changes and high-frequency transducers with magnified images should be employed. GB lesions are divided into polypoid lesions (GPLs) and wall thickening (GWT). Read More

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[Clinical features and prognosis of patients with leptomeningeal metastases].

Zhonghua Yi Xue Za Zhi 2021 Apr;101(16):1154-1159

Department of Neurology, Henan Provincial People's Hospital, Zhengzhou 450003, China.

To describe the clinical manifestations, neuroimaging, cerebrospinal fluid(CSF) cytology and prognosis of Leptomeningeal metastases(LM). The clinical manifestations, imaging features and CSF cytology of LM patients admitted to Henan Provincial People's Hospital from May 1, 2015 to May 31, 2020 were retrospectively analyzed. The overall survival (OS) was evaluated by the time from the diagnosis of LM to death. Read More

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Endoscopic drainage for management of infected necrosis following EUS-TA in a patient with pancreatic cancer: A case report.

Medicine (Baltimore) 2021 Apr;100(16):e25466

Department of Gastroenterology and Hepatology, Chonnam National University Medical School, Gwangju, South Korea.

Rationale: Endoscopic ultrasonography-guided tissue acquisition (EUS-TA) has become the norm for the diagnosis of pancreatic solid lesions. EUS-TA is relatively safe, but various complications can occur. Infected pancreatic necrosis (IPN) is a rare but serious complication. Read More

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Xanthogranulomatous cholecystitis mimicking gallbladder cancer on F-fluorodeoxyglucose positron emission tomography/computed tomography scan.

World J Nucl Med 2021 Jan-Mar;20(1):93-95. Epub 2020 Dec 12.

Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.

The abnormal thickening of the gallbladder (GB) wall can be caused by a malignant condition like gallbladder carcinoma or by benign lesions such as chronic cholecystitis or xanthogranulomatous cholecystitis (XGC). Mural thickening is a common finding between them as fluorodeoxyglucose (FDG) can be taken up by inflammatory cells also. Here, we present a patient with irregular thickening of the GB wall which was suspected to of GB carcinoma since FDG positron emission tomography/computed tomography scan showed increased tracer uptake in the lesion. Read More

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December 2020

[A case of simultaneous multicentric cancer in the gallbladder duct and the common bile duct without pancreaticobiliary maljunction].

Nihon Shokakibyo Gakkai Zasshi 2021 ;118(4):366-373

Department of Pathology, Tokai University School of Medicine.

A 68-year-old man who underwent cholecystectomy for acute cholecystitis and was diagnosed with gallbladder duct carcinoma was referred to our hospital. Postoperative computed tomography showed thickening of the middle to lower bile duct without any tumorous lesions. Endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed irregular wall thickening of the lower bile duct and apparent infiltration of gallbladder duct tumor to the common bile duct without pancreaticobiliary maljunction. Read More

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Update in clinical management for gallbladder neuroendocrine carcinoma.

Medicine (Baltimore) 2021 Apr;100(14):e25449

Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou.

Background: Gallbladder neuroendocrine carcinoma (GB-NEC) is rare and there are few reports at present. We sought to review the current knowledge of GB-NEC and provide recommendations for clinical management.

Methods: A systemic literature research was conducted in the websites of Pubmed, Medline, Web of Science, CNKI, Wanfang Data using the keywords including gallbladder combined with neuroendocrine carcinoma or neuroendocrine tumor or neuroendocrine neoplasm. Read More

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S100P as a marker for poor survival and advanced stage in gallbladder carcinoma.

Ann Diagn Pathol 2021 Jun 22;52:151736. Epub 2021 Mar 22.

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States. Electronic address:

Aims: Gallbladder carcinomas usually present in advanced stages and has a dismal prognosis despite modern imaging techniques and aggressive surgical intervention. Identification of biologic markers for early diagnosis and improved therapeutic strategies is thus of paramount importance. S100P has been identified in a variety of malignant neoplasms of the gastrointestinal and pancreaticobiliary systems, but it is not yet known if S100P expression is associated with clinically-relevant characteristics of gall bladder carcinoma. Read More

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Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial.

Lancet Oncol 2021 05 30;22(5):690-701. Epub 2021 Mar 30.

Department of Medical Oncology, The Christie NHS Foundation Trust/Institute of Cancer Sciences, University of Manchester, Manchester, UK; Division of Cancer Sciences, University of Manchester, Manchester, UK. Electronic address:

Background: Advanced biliary tract cancer has a poor prognosis. Cisplatin and gemcitabine is the standard first-line chemotherapy regimen, but no robust evidence is available for second-line chemotherapy. The aim of this study was to determine the benefit derived from second-line FOLFOX (folinic acid, fluorouracil, and oxaliplatin) chemotherapy in advanced biliary tract cancer. Read More

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Primary clear cell carcinoma of gallbladder arising in porcelain gallbladder.

BMJ Case Rep 2021 Apr 1;14(4). Epub 2021 Apr 1.

Diagnostic and Interventional Radiology, All India Institute of Medical Sciences Jodhpur, Jodhpur, India.

Gallbladder carcinomas (GBCs) are the most common carcinomas of the biliary tract. The clear cell variant is encountered rarely, accounting for approximately 1% of all GBCs.Due to its rarity, the exact incidence and pathogenesis of this variant are unknown. Read More

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Surgery of the primary tumour in 201 patients with high-grade gastroenteropancreatic neuroendocrine and mixed neuroendocrine-non-neuroendocrine neoplasms.

J Neuroendocrinol 2021 May 26;33(5):e12967. Epub 2021 Mar 26.

ENETS Neuroendocrine Tumor Centre of Excellence, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

The benefit of surgery in high-grade gastroenteropancreatic neuroendocrine neoplasms (GEP NEN) and mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) is uncertain. The present study aimed to investigate outcomes after tumour surgery in patients with high-grade (Ki-67 > 20%) GEP NEN or MiNEN stage I-III or stage IV. We analysed data from patients treated in the period 2007-2015 at eight Nordic university hospitals. Read More

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A case of idiopathic retroperitoneal fibrosis presenting as gallbladder carcinoma.

BMC Surg 2021 Mar 25;21(1):162. Epub 2021 Mar 25.

Department of Surgery, Changxing People's Hospital, No. 66, Taihu Road, Changxing, Huzhou, 313100, Zhejiang, China.

Background: Retroperitoneal fibrosis (RPF) is a rare disease with a poor prognosis characterized by systemic inflammation and fibroinflammatory tissue. Idiopathic RPF (IRPF) accounts for approximately two-thirds of RPF cases.

Case Presentation: A 56-year-old female patient with abdominal distension was admitted to Changxing Hospital. Read More

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The predictive value of systemic immune inflammation index for postoperative survival of gallbladder carcinoma patients.

J Surg Oncol 2021 Jul 25;124(1):59-66. Epub 2021 Mar 25.

Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Background: Growing evidence indicates that systemic immune inflammation index (SII) can predict the prognosis of various solid tumors. The objective of this study aimed to investigate the efficacy of SII in predicting the prognosis of gallbladder carcinoma (GBC) patients after radical surgery.

Methods: A consecutive series of 93 patients with GBC who underwent radical resection were enrolled in the retrospective study. Read More

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Xanthogranulomatous cholecystitis: Diagnosis and management.

J Visc Surg 2021 Mar 16. Epub 2021 Mar 16.

Department of digestive surgery and liver transplantation, University Hospital Center Croix Rousse, Hospices Civils de Lyon, Claude-Bernard-Lyon-1, 69004 Lyon, France.

Xanthogranulomatous cholecystitis (XGC) is a rare form of cholecystitis, characterized by the presence of xanthogranuloma, prominent yellow structures within the gallbladder wall that is very often lithiasic. When XGC presents in its pseudo-tumoral form with occasional adjacent organ involvement, it can mimic gallbladder carcinoma (GBC). The etiopathogenesis of XGC is inflammatory destruction of Rokitansky-Aschoff sinuses containing biliary and cholesterol pigments within the gallbladder wall; this leads to a florid granulomatous histiocytic inflammatory reaction. Read More

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Combined Ultrasound and CT-Guided Iodine-125 Seeds Implantation for Treatment of Residual Hepatocellular Carcinoma Located at Complex Sites After Transcatheter Arterial Chemoembolization.

Front Oncol 2021 2;11:582544. Epub 2021 Mar 2.

Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Purpose: The purpose of this study was to evaluate the efficacy and safety of iodine-125 (I) seeds implantation under ultrasound and computed tomography (CT) guidance in the treatment of residual hepatocellular carcinoma (HCC) located at complex sites after transcatheter arterial chemoembolization (TACE).

Methods: This retrospective study analyzed the consecutive medical records of 31 HCC patients with residual tumors located at complex sites (such as large blood vessels, gallbladder, diaphragm dome, etc.) after TACE from May 2014 to December 2018, all of whom received I seeds implantation therapy. Read More

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Mixed neuroendocrine-non-neuroendocrine neoplasms of the gallbladder: a case report.

Surg Case Rep 2021 Mar 17;7(1):70. Epub 2021 Mar 17.

Department of Pathology, Omihachiman Community Medical Center, 1379 Tsuchidacho, Omihachimanshi, Shiga, 523-0082, Japan.

Background:  Primary neuroendocrine tumors of the gallbladder (GB-NETs) are rare, accounting for 0.5% of all NETs and 2.1% of all gallbladder cancers. Read More

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The giant resectable carcinoma of gall bladder-a case report.

BMC Surg 2021 Mar 16;21(1):133. Epub 2021 Mar 16.

Department of Surgery, Maulana Azad Medical College, New Delhi, India.

Background: Gall bladder cancer (GBC) is the fifth most common malignancy in the gastrointestinal system and the most common malignancy of the biliary system. GBC is a very aggressive malignancy having a 5 year survival rate of 19%. Giant Gall Bladder (GGB) is an uncommon condition that can result from cholelithiasis or chronic cholecystitis and rarely with malignancy. Read More

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[Attach importance to the standardized diagnosis and treatment of gallbladder carcinoma].

Y B Liu W Chen

Zhonghua Wai Ke Za Zhi 2021 Apr 1;59(4):249-254. Epub 2021 Apr 1.

Department of Biliary-Pancreatic Surgery,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China.

Gallbladder carcinoma,characterized by concealed onset,rapid development,and poor prognosis,needs to be valued by clinicians.The key to improving its prognosis remains early diagnosis and standardized therapy.Improving the sensitivity and accuracy of hematological and imaging diagnosis and early detection of specific molecular diagnostic targets for gallbladder cancer are helpful for early diagnosis and treatment. Read More

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Bladder-to-bladder metastasis: gallbladder cancer metastasising to the urinary bladder.

Ann R Coll Surg Engl 2021 Apr 8;103(4):e116-e119. Epub 2021 Mar 8.

Dartford and Gravesham NHS Trust, Dartford, Kent, UK.

We report a 48-year-old fit and healthy woman who was incidentally diagnosed to have adenocarcinoma of gallbladder after laparoscopic cholecystectomy. Subsequent imaging showed no evidence of regional or distant spread. She was scheduled for elective laparotomy and resection of gallbladder bed, but during laparotomy frozen section analysis of an incidentally discovered peritoneal deposit confirmed metastasis, so the procedure was abandoned. Read More

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Low-Grade Dysplastic Intracholecystic Papillary Neoplasia: A Case Report.

Am J Case Rep 2021 Mar 3;22:e929788. Epub 2021 Mar 3.

Department of General Surgery, Tondela-Viseu Hospital Center, Viseu, Portugal.

BACKGROUND The World Health Organization classification of premalignant gallbladder lesions includes adenomas, intraductal papillary neoplasms, biliary intraepithelial neoplasia, and intracystic papillary neoplasms. Noninvasive neoplastic lesions >1 cm that originate from the pancreatobiliary system are defined as intraductal papillary neoplasia when they occur in the biliary ducts. The clinical and pathological features of preinvasive lesions arising in the gallbladder are not yet well defined. Read More

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Hepatobiliary morbidities detected by ultrasonography in Opisthorchis viverrini-infected patients before and after praziquantel treatment: a five-year follow up study.

Acta Trop 2021 May 3;217:105853. Epub 2021 Feb 3.

Tropical Disease Research Laboratory, Department of Pathology, Faculty of Medicine, Khon Kaen 40002, Thailand.

Infection of the liver fluke, Opisthorchis viverrini (OV) is an important public health problem in northeast Thailand and adjacent countries, where people have a habit of eating raw or undercooked fish. A community case-control study was carried out with 8,936 participants from 89 villages, in Khon Kaen province, Thailand. There were 3,359 OV-infected participants all of whom underwent ultrasonography of upper abdomen for the evaluation of hepatobiliary morbidity. Read More

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Synchronous gallbladder metastasis of renal cell carcinoma presenting as a gallbladder polyp: A case report.

Medicine (Baltimore) 2021 Jan;100(3):e24037

Department of Surgery.

Rationale: Gallbladder polyps are common in the general population, but gallbladder metastasis of renal cell carcinoma (RCC) is very rare. In a patient with RCC diagnosed with a small gallbladder polyp that does not meet the traditional size criteria, the surgeon faces a dilemma of whether cholecystectomy should be performed given the possibility of metastasis.

Patient Concerns: A 55-year-old man who had received a left nephrectomy for RCC presented with a gallbladder polyp that was noted at the time of the nephrectomy. Read More

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January 2021

[Primary hepatoid adenocarcinoma in lung, gallbladder and bladder: a clinicopathological observation of three cases].

Zhonghua Bing Li Xue Za Zhi 2021 Feb;50(2):137-139

Department of Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

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February 2021

Pembrolizumab-induced large duct cholangiopathy: Diagnosis and follow.up imaging.

J Postgrad Med 2021 Jan-Mar;67(1):43-45

Department of Radiology and Imaging, Tata Medical Center, 14 Main Arterial Road (E.W), New Town, West Bengal, India.

Immune-checkpoint inhibitor mediated hepatobiliary injury is an emerging concern in cancer treatment. Most of these adverse reactions are attributed to nivolumab and are characterized by panlobular hepatitis. Large duct cholangiopathy related to these drugs is extremely rare. Read More

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A narrative review of gallbladder adenomyomatosis: what we need to know.

Ann Transl Med 2020 Dec;8(23):1600

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China.

Gallbladder adenomyomatosis (GA) is increasingly encountered in clinical practice due to increasing use of imagings especially ultrasound (US). Clinicians need to know what is the implication of this condition and its proper management. GA is a degenerative and proliferative disease characterized by excessive epithelial proliferation associated with hypertrophy of muscularis propria. Read More

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December 2020