1,658 results match your criteria Gallbladder Carcinoma Imaging

Mixed neuroendocrine-non-neuroendocrine neoplasm of the gallbladder: case report and literature review.

Diagn Pathol 2022 Jun 17;17(1):51. Epub 2022 Jun 17.

Hospital Information Center of Heilongjiang Province Affiliated to Harbin Institute of Technology, Harbin, 150001, Heilongjiang Province, China.

Background: Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of the gallbladder are rare malignancies. Here we presented two cases and reviewed the related literature.

Case Presentation: Our two patients were postoperatively diagnosed with gallbladder MiNENs, which pathologically consisted of a large cell neuroendocrine carcinoma and papillary adenocarcinoma. Read More

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Early Recurrence in Resected Gallbladder Carcinoma: Clinical Impact and Its Preoperative Predictive Score.

Ann Surg Oncol 2022 Jun 6. Epub 2022 Jun 6.

Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Sunto-Nagaizumi, Shizuoka, Japan.

Background: Surgical resection is the only potentially curative therapy for gallbladder carcinoma (GBC). However, the postoperative recurrence rate is high (approximately 50%), and recurrence occasionally develops early after surgery.

Patients And Methods: A total of 139 patients who underwent macroscopically curative resection for GBC between 2002 and 2018 were retrospectively reviewed. Read More

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Contrast-enhanced CT radiomics for prediction of recurrence-free survival in gallbladder carcinoma after surgical resection.

Eur Radiol 2022 May 25. Epub 2022 May 25.

Department of Hepatobiliary Pancreatic Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.

Objectives: Gallbladder carcinoma (GBC) is the most common and aggressive biliary tract malignancy with high postoperative recurrence rates. This single-center study aimed to develop and validate a radiomics signature to estimate GBC recurrence-free survival (RFS).

Methods: This study retrospectively included 204 consecutive patients with pathologically diagnosed GBC and were randomly divided into development (n = 142) and validation (n = 62) cohorts (7:3). Read More

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Value of Multislice Spiral CT in Differential Diagnosis of Thick-Wall Gallbladder Carcinoma and Chronic Cholecystitis.

Hua Han Jun Han

Contrast Media Mol Imaging 2022 6;2022:5459779. Epub 2022 May 6.

Department of Radiology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China.

To summarize the value of multislice spiral CT (MSCT) in the differential diagnosis of thick-wall gallbladder carcinoma (TWGC) and chronic cholecystitis (CC), the clinical data of 36 patients with TWGC and 60 patients with chronic cholecystitis who were treated in our hospital from January 2017 to May 2021 were retrospectively analyzed, and the CT image features and diagnostic accuracy of the patients were summarized. Compared with the CC group, the proportions of disruption of gallbladder mucosa line, blurred gallbladder outline, high obstruction of biliary tract, lymphomegaly, adjacent invasion, peritoneal effusion, wall nodules, and the gallbladder wall thickness in the TWGC group were higher, with statistical significance ( < 0.05). Read More

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Unusual presentation of small cell carcinoma with diffuse tracheal wall thickening leading to delayed diagnosis.

BMJ Case Rep 2022 05 12;15(5). Epub 2022 May 12.

Hematology/Oncology, Feist-Weiller Cancer Center, Shreveport, Louisiana, USA.

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Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Carcinoma on 68Ga-FAPI-04 PET.

Clin Nucl Med 2022 Apr 29. Epub 2022 Apr 29.

From the Department of Nuclear Medicine, Changhai Hospital, Navy Military Medical University.

Abstract: 68Ga-FAPI-04 has great potential for the detection and staging evaluation of a variety of tumors. We report a case of suspected gallbladder carcinoma that was enrolled in a prospective study of 68Ga-FAPI-04 imaging at our institution. This case was later histopathologically confirmed as xanthogranulomatous cholecystitis. Read More

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Feasibility of therapeutic endoscopic ultrasound in the bridge-to-surgery scenario: The example of pancreatic adenocarcinoma.

World J Gastroenterol 2022 Mar;28(10):976-984

Pancreatobiliary Endoscopy and EUS Division, Pancreas Translational & Clinical Research Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan 20132, Italy.

Upfront resection is becoming a rarer indication for pancreatic ductal adenocarcinoma, as biologic behavior and natural history of the disease has boosted indications for neoadjuvant treatments. Jaundice, gastric outlet obstruction and acute cholecystitis can frequently complicate this window of opportunity, resulting in potentially deleterious chemotherapy discontinuation, whose resumption relies on effective, prompt and long-lasting management of these complications. Although therapeutic endoscopic ultrasound (t-EUS) can potentially offer some advantages over comparators, its use in potentially resectable patients is primal and has unfairly been restricted for fear of potential technical difficulties during subsequent surgery. Read More

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Incidental finding of a large polypoidal gallbladder mass diagnosed as papillary adenocarcinoma - A case report.

Int J Surg Case Rep 2022 May 10;94:107046. Epub 2022 Apr 10.

Department of Surgery, Manipal College of Medical Sciences, Pokhara, Nepal.

Introduction And Importance: Lesions which project from the gallbladder wall into its lumen are known as gallbladder polyps. Nearly 5% of all adults have gallbladder polyps, the majority are pseudo-polyps with no neoplastic potential. Although gallbladder polyps are commonly found in cholecystectomy specimen, only a very few gallbladder polyps present as carcinoma in a polypoid lesion. Read More

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Gallbladder Intramucosal Carcinoma Arising in a Cholesterol Polyp: A Case Report.

Cureus 2022 Mar 6;14(3):e22898. Epub 2022 Mar 6.

Gastroenterological Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, JPN.

Cholesterol polyp is the most common benign disease of gallbladder polyps, and is considered not to be the origin of malignancy. Herein, we report a rare case of a well-differentiated adenocarcinoma arising in a gallbladder cholesterol polyp. A pedunculated mulberry-like gallbladder polyp diagnosed with a cholesterol polyp preoperatively consisted of two distinct components macroscopically: a yellow-whitish lobulated lesion and a brownish irregular lesion. Read More

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Polypoid invasive carcinoma of bile duct: report of four cases.

Clin J Gastroenterol 2022 Jun 25;15(3):630-634. Epub 2022 Mar 25.

Department of Digestive Surgery, Fukui Prefecture Saiseikai Hospital, Fukui, Japan.

Recently, "polypoid invasive carcinoma (PICA)" showing grossly visible polypoid, invasive carcinoma with no adenoma component was proposed as a neoplastic polyp of the gallbladder. Herein, we report four cases of PICA of the bile duct. PICA cases of bile duct showed single, sessile polypoid growth grossly, and polypoid components were composed of invasive carcinoma of papillary/tubular patterns with active desmoplasia, and invaded directly and continuously into the bile duct wall and periductal tissue. Read More

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Phase II Study of Ramucirumab in Advanced Biliary Tract Cancer Previously Treated By Gemcitabine-Based Chemotherapy.

Clin Cancer Res 2022 Jun;28(11):2229-2236

Division of Cancer Medicine, Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Purpose: VEGF receptor-2 (VEGFR-2)-mediated angiogenesis contributes to pathogenesis of biliary tract cancers (BTC). We investigated ramucirumab, a mAb targeting VEGFR-2 for treatment of advanced, chemorefractory BTC.

Patients And Methods: This is a phase II, single-arm trial for advanced, unresectable, pre-treated patients with BTC with ECOG 0/1, adequate liver, renal, and marrow functions. Read More

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A case of undifferentiated carcinoma of the gallbladder with severe inflammation and difficult preoperative chemotherapy.

Clin J Gastroenterol 2022 Jun 19;15(3):623-629. Epub 2022 Mar 19.

Department of Surgery, Hirakata Hospital, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1191, Japan.

Undifferentiated carcinoma (UC) is relatively rare among gallbladder cancers, and the prognosis is poor compared to gallbladder adenocarcinoma. We report a 64-year-old man with gallbladder UC who underwent radical surgery and achieved long-term survival. He presented with a chief complaint of abdominal distension and loss of appetite. Read More

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Incidental adenocarcinoma of the gallbladder in a patient with Y insertion gallbladder duplication in the context of recurrent biliary colic: A video case report.

Medicine (Baltimore) 2022 Feb;101(8):e28829

Department of General Surgery, Calvary Mater Newcastle, Australia.

Rationale: Gallbladder cancer is the most common malignancy of the biliary tree. Despite this, the only curative therapy remains surgical resection of the lesion achieving microscopically clear margins before malignant spread has occurred. Gallbladder duplication is an uncommon anatomical variance which occurs globally. Read More

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February 2022

Intracholecystic papillary neoplasm associated with invasive carcinoma of the remnant gallbladder after subtotal cholecystectomy: a case report.

Surg Case Rep 2022 Feb 21;8(1):31. Epub 2022 Feb 21.

Department of Surgery, Hamanomachi Hospital, 3-3-1, Nagahama, Chuo-ku, Fukuoka, 810-8539, Japan.

Background: Intracholecystic papillary neoplasm (ICPN) of the gallbladder is a rare tumor and a relatively new concept. Therefore, the natural history and imaging characteristics of ICPN have not yet been fully documented. Moreover, cases who underwent curative resection for remnant gallbladder cancer, including ICPN with associated invasive carcinoma, have been rarely reported. Read More

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February 2022

Recurrent Gallbladder Carcinoma With pMMR/MSS Achieved a Complete Response Following Camrelizumab Combined With Apatinib: A Case Report.

Front Oncol 2021 13;11:783158. Epub 2022 Jan 13.

Department of Oncology, Ganzhou People's Hospital (The Affiliated Ganzhou Hospital of Nanchang University), Ganzhou, China.

Gallbladder carcinoma (GBC) with proficient mismatch repair (pMMR)/microsatellite stable (MSS) is associated with limited response to programmed death-1 (PD-1) inhibitor monotherapy. Limited data of PD-1 blockade combined with anti-angiogenic therapy in GBC are reported. One recurrent GBC patient with pMMR/MSS was treated with camrelizumab plus apatinib. Read More

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January 2022

Carcinosarcoma of gallbladder: A world review.

World J Clin Oncol 2021 Dec;12(12):1244-1263

Department of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore.

Background: Gallbladder carcinosarcoma is a rare hepatobiliary tumor comprising of both carcinomatous and sarcomatous components. Due to its rarity, the literature with regards to the topic is scarce and currently lacking, spanning less than 100 cases.

Aim: To summarize the current literature on gallbladder carcinosarcoma. Read More

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December 2021

Port-Site Metastases in Incidentally Detected Carcinoma Gall Bladder: Role of 18F-FDG PET/CT and Patient Outcome.

J Gastrointest Cancer 2022 Mar 24;53(1):16-21. Epub 2022 Jan 24.

Department of Nuclear Medicine, SGPGIMS, Lucknow, India.

Background: Incidentally detected gall bladder carcinoma (IGBC) is occasionally encountered after cholecystectomy for benign gall bladder disease. Rarely these patients may present with port-site metastases (PSM) in follow-up. We retrospectively assessed the role of 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) in them. Read More

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Locally advanced gallbladder cancer treated with effective chemotherapy and subsequent curative resection: a case report.

J Med Case Rep 2022 Jan 17;16(1):30. Epub 2022 Jan 17.

Department of Surgery, National Hospital Organization Higashihiroshima Medical Center, 513 Jike, Saijo-cho, Higashihiroshima, Hiroshima, 739-0041, Japan.

Background: Surgical resection of gallbladder cancer with negative margins is the only potentially curative therapy. Most patients with gallbladder cancer are diagnosed in an advanced stage and, despite the availability of several chemotherapies, the prognosis remains dismal. We report a case of locally advanced gallbladder cancer that was successfully treated with effective cisplatin plus gemcitabine, followed by curative resection. Read More

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January 2022

The Unusual Presentation of a Single Case of Synchronous Metastatic Clear Cell Renal Cell Carcinoma to the Gallbladder: A Case Report and Literature Review.

Curr Health Sci J 2021 Jul-Sep;47(3):457-461. Epub 2021 Sep 30.

Department of Medicine: Hematology and Oncology, Augusta University, Augusta, GA, USA.

Clear cell renal cell carcinoma, accounts for approximately 70% of all adult renal tumors. This disease is well known for its high metastatic potential, with estimates of 25-50% of patients reporting metastasis to distant structures. However, there have only been several reported cases in medical literature describing hematogenous spread to the gallbladder, with the majority occurring metachronously, in males, and with multiple metastases. Read More

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September 2021

[Local and locoregional treatment of intrahepatic cholangiocarcinoma].

Radiologe 2022 Mar 3;62(3):247-252. Epub 2022 Jan 3.

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Deutschland.

Clinical/methodical Issue: In the new edition of the German S3-guideline published in June 2021, the diagnosis and treatment of cholangiocarcinoma (CCA) and gallbladder carcinoma are addressed for the first time. This article discusses the local and locoregional treatment options for intrahepatic CCA (iCCA).

Standard Radiological Methods: Mortality is high in iCCA and the incidence is rising. Read More

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Small Cell Carcinoma of Gallbladder With Nodal Metastasis Mimicking As Synchronous Malignancy in Gallbladder and Common Bile Duct.

Cureus 2021 Nov 18;13(11):e19707. Epub 2021 Nov 18.

Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Small cell carcinoma of the gallbladder is an extremely rare disease. Even with current aggressive and diverse treatments, small cell carcinoma of the gallbladder has an extremely poor prognosis. The presence of synchronous malignancies in the gallbladder and the biliary tract is even rare. Read More

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November 2021

Segnet Network Algorithm-Based Ultrasound Images in the Diagnosis of Gallbladder Stones Complicated with Gallbladder Carcinoma and the Relationship between P16 Expression with Gallbladder Carcinoma.

J Healthc Eng 2021 21;2021:2819986. Epub 2021 Dec 21.

Endocrine Department, Affiliated Hospital of Hebei Engineering University, Handan 056002, Hebei, China.

The study focused on how to improve the diagnostic coincidence rate of patients with gallbladder stones and gallbladder cancer based on an optimized Segnet network algorithm and the relationship of gallbladder cancer with multiple tumor suppressor 1 (P16). 300 patients diagnosed with gallbladder cancer in the hospital were selected as the research subjects. The pyramid pooling operation was incorporated into the original Segnet network algorithm, and its performance was evaluated, factoring into the intersection of union (IoU), algorithm precision (Pre), and recall rate (Recall). Read More

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January 2022

Combination of portal vein embolization and neoadjuvant chemotherapy for locally advanced gallbladder cancer requiring extended hepatectomy - A novel approach.

Indian J Gastroenterol 2021 Dec 30;40(6):580-589. Epub 2021 Dec 30.

Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Center, Sector -5, Rohini, New Delhi, 110 085, India.

Background: Locally advanced gallbladder cancer (GBC) may require extended hepatectomy. Portal vein embolization (PVE) can lead to hypertrophy of future liver remnant (FLR), and neoadjuvant chemotherapy (NACT) can be used in this cohort, with additional advantage of downstaging tumors as well as preventing progression while waiting for liver regeneration. Here, we share our experience of combining NACT along with PVE in locally advanced GBC requiring major hepatectomy. Read More

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December 2021

A Unique Presentation of Metastatic Gallbladder Carcinoma.

Case Rep Surg 2021 16;2021:6455540. Epub 2021 Dec 16.

Saint Louis University School of Medicine, USA.

Gallbladder carcinoma can be challenging to diagnose and treat and usually leads to poor outcome, due to its aggressive nature and the nonspecific clinical presentation at early stage. We describe an interesting case of a 60-year-old female who presented with stage 3 appendiceal carcinoma after appendectomy was performed outside hospital. Further imaging workup demonstrated enlarged ovarian cysts and porcelain gallbladder. Read More

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December 2021

Paraneoplastic chorea associated with gallbladder cancer.

BMJ Case Rep 2021 Dec 22;14(12). Epub 2021 Dec 22.

Department of Neurology, Kanazawa Municipal Hospital, Kanazawa, Japan.

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December 2021

Biodistribution and image characteristics of I-positron emission tomography in dogs with neuroendocrine neoplasia.

Vet Radiol Ultrasound 2022 May 16;63(3):298-305. Epub 2021 Dec 16.

Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA.

Radioactive iodine is frequently used for staging of human thyroid carcinomas. Iodine-124 scans performed using position emission tomography (PET) allow for more precise dosimetry of therapeutic radioiodine. The distribution of I-124 has not previously been described in veterinary medicine. Read More

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Noninvasive preoperative differential diagnosis of gallbladder carcinoma and xanthogranulomatous cholecystitis: A retrospective cohort study of 240 patients.

Cancer Med 2022 01 27;11(1):176-182. Epub 2021 Nov 27.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.

Background: Xanthogranulomatous cholecystitis (XGC) is an extremely rare entity. Due to XGC's clinical and radiological resemblance to gallbladder carcinoma (GBC), intraoperative frozen section during cholecystectomy is often performed to exclude the diagnosis of GBC. Our study is aiming to find a noninvasive indicator of XGC. Read More

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January 2022

Xanthogranulomatous cholecystitis on fusion of the planes of the liver.

Radiol Case Rep 2022 Jan 12;17(1):208-211. Epub 2021 Nov 12.

Department of Radiology, Avicenne Military Hospital, Marrakech, Morocco.

Xanthogranulomatous cholecystitis (CXG) is a rare entity of cholecystitis, characterized by the presence of xanthogranulomas within the gallbladder wall, that could be misdiagnosed as a vesicular carcinoma. We report a case of 66-year-old man with xanthogranulomatous cholecystitis associated with an incidental finding of a fusion of the planes of the liver which is a rare anatomic variant. Imaging especially ultrasounds, CT scan, and MRI play a key role in the characterization of those anomaly, thus avoiding a non-suitable surgical procedure. Read More

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January 2022

[Mucinous adenocarcinoma of the gallbladder: report of 5 cases].

Zhonghua Yi Xue Za Zhi 2021 Nov;101(42):3506-3508

Department of Hepatobiliary Surgery, the First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha 410005, China.

The clinical manifestations, laboratory and imaging results, diagnosis and treatment and prognosis of 5 patients with mucinous adenocarcinoma of the gallbladder were analyzed. It was found that the clinical characteristics of mucinous adenocarcinoma of the gallbladder were very similar to that of gallbladder malignant tumor, and it was difficult to differentiate. Ultrasound guided gallbladder needle biopsy can confirm the diagnosis before surgery. Read More

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November 2021

Focal neuroendocrine carcinoma mixed with adenocarcinoma of the gallbladder with aggressive lymph node metastasis in a patient who did not meet the mixed neuroendocrine-non-neuroendocrine neoplasm criteria.

Clin J Gastroenterol 2022 Feb 12;15(1):185-191. Epub 2021 Nov 12.

Department of General and Gastrointestinal Surgery, Tokyo Saiseikai Central Hospital, 1-4-17 Mita, Minato-ku, Tokyo, 108-0073, Japan.

A 70-year-old Japanese woman who was treated for interstitial pneumonia (IP) with steroid therapy developed cholecystitis. A serial computed-tomography (CT) imaging showed irregular thickness of the fundus wall of the gallbladder and two rapidly enlarged lymph nodes (LNs): number (no.) 12 and no. Read More

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February 2022