41,694 results match your criteria Gallbladder Carcinoma Imaging


Accuracy of Right Upper Quadrant Ultrasound in Estimating Gallbladder Wall Thickness.

Surg Laparosc Endosc Percutan Tech 2018 Dec 4. Epub 2018 Dec 4.

Departments of Surgery.

Objective: Ultrasound (US) evaluation of biliary pathology can be influenced by a variety of factors. This study examines the effect of patient specific factors on the accuracy of sonographic evaluation of gallbladder wall thickness (GBW).

Methods: We performed a retrospective review of all patients who underwent cholecystectomy at a single institution from November 2012 to October 2015. Read More

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December 2018
1 Read

Incidental Hepatic Tissue Obtained via Routine Cholecystectomy.

Int J Surg Pathol 2018 Dec 6:1066896918817374. Epub 2018 Dec 6.

2 University of California, Irvine, CA, USA.

Background: The hepatic tissue that may occupy specimens from routine cholecystectomies has yet to be studied. Our objectives were to determine the prevalence of hepatic tissue obtained at routine cholecystectomy, to determine whether such hepatic tissue can histologically withstand technical artifacts commonly associated with cholecystectomy, and to determine whether examining such hepatic tissue has diagnostic utility.

Materials And Methods: We retrospectively reviewed 50 specimens from routine cholecystectomies that were performed by surgeons who lacked knowledge of our study. Read More

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December 2018
1 Read

Diagnostic laparoscopy to investigate unexplained lactic acidosis in critically ill patients - A descriptive single centre cohort study.

Ann Med Surg (Lond) 2018 Dec 13;36:231-234. Epub 2018 Nov 13.

Department of Surgery, University Hospital Hairmyres, NHS Lanarkshire, East Kilbride, G75 8RG, Scotland, UK.

Introduction: Unexplained lactic acidosis (LA) in a critically ill patient often prompts investigations to rule out any reversible intra-abdominal cause. Equivocal results can lead to an emergency laparotomy (EL) with subsequent high morbidity and mortality rates. Our objective was to determine the clinical impact of urgent diagnostic laparoscopy (UDL) in such patients. Read More

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December 2018
1 Read

High-Risk Comorbidity Combinations in Older Patients Undergoing Emergency General Surgery.

J Am Geriatr Soc 2018 Dec 2. Epub 2018 Dec 2.

Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio.

Background/objectives: Over a million older patients in the United States are admitted yearly for emergency general surgery (EGS) conditions. Seven procedure types dominate: colon, small bowel, gallbladder, ulcer disease, adhesiolysis, appendix, and laparotomy operations. A higher comorbidity burden is known to increase mortality in this population, but the impact of specific comorbidity combinations is unknown. Read More

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December 2018
1 Read

Intracholecystic papillary-tubular neoplasm of the gallbladder originating in the cystic duct with extensive intraepithelial progress in the common bile duct.

Clin J Gastroenterol 2018 Nov 30. Epub 2018 Nov 30.

Department of Gastroenterology, Sendai City Medical Center, 5-22-1, Tsurugaya, Miyagino-ku, Sendai, Miyagi, Japan.

A 59-year-old man with anorexia who had a history of cholecystectomy was referred to our hospital. Imaging examinations revealed a contrast-enhanced tumor in the residual cystic duct and a part of the common bile duct. Endoscopic retrograde cholangiopancreatography and peroral-cholangioscopy showed a papillary tumor with movement and a change in the shape. Read More

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November 2018
1 Read

A case of hemobilia secondary to cancer of the gallbladder confirmed by cholangioscopy and treated with a fully covered self-expanding metal stent.

VideoGIE 2018 Dec 4;3(12):381-383. Epub 2018 Oct 4.

Department of Gastroenterology and Hepatology, St George Hospital, Kogarah, Australia.

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December 2018
1 Read

Cholangioscopy in the digital era.

Transl Gastroenterol Hepatol 2018 29;3:82. Epub 2018 Oct 29.

Division of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, FL, USA.

Cholangioscopy allows direct visualization and subsequent therapeutic maneuvers of the biliary ductal system. With advances in endoscopic and imaging technology, cholangioscopy has become an important modality for the diagnosis of indeterminate biliary strictures and an essential therapeutic tool for difficult to remove biliary stones. Enhanced imaging and operability of the latest generation cholangioscopes have further expanded their clinical applications to include ductal tumor ablation, gallbladder drainage, access to difficult to reach branches of the biliary tree, and biliary foreign body manipulation. Read More

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October 2018
1 Read

Double cholecystectomy in case of accessory gallbladder: Not as easy as two cholecystectomies.

Hepatobiliary Pancreat Dis Int 2018 Nov 24. Epub 2018 Nov 24.

Department of General Surgery and Liver Transplantation, Hospices Civils de Lyon, Croix-Rousse University Hospital, Lyon, France; Ecole Doctorale EDISS 205, Université Lyon 1, EMR 3738, Lyon, France.

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November 2018
1 Read

Endogenous endophthalmitis due to Klebsiella pneumoniae from an infected gallbladder.

Can J Ophthalmol 2018 Dec 16;53(6):e258-e260. Epub 2018 Mar 16.

University of Alberta, Edmonton, Alta. Electronic address:

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December 2018
1 Read

Modifications to Expose Porta Hepatis for Laparoscopic Portoenterostomy Easier in Biliary Atresia.

J Surg Res 2019 Jan 10;233:368-375. Epub 2018 Sep 10.

Department of General surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu, China.

Background: Laparoscopic Kasai portoenterostomy (LKPE) is generally regarded to have a poorer outcome for surgical treatment of uncorrectable biliary atresia. We herein described our initial experience of some modifications to make LKPE easier in the treatment of type III biliary atresia (BA).

Methods: During the period July 2012-October 2016, a total of 25 infants with type III BA were treated with a modified LKPE technique. Read More

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January 2019
1 Read

Gallbladder Metastasis From Conjunctival Melanoma.

Clin Nucl Med 2018 Dec 3. Epub 2018 Dec 3.

From the Department of Nuclear Medicine, Institut Curie, PSL Research University, Paris, France.

Malignant conjunctival melanoma is a rare tumor. A 46-year-old woman with a history of locally recurrent left conjunctival melanoma was followed by F-FDG PET/CT. Four years after the local recurrence treated by orbital exenteration, the follow-up PET/CT scan showed an incidental intense FDG uptake mass infiltrating the gallbladder associated with a low uptake of an infracentimetric pulmonary nodule. Read More

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December 2018
1 Read

Identification of a Small Molecule Anti-biofilm Agent Against .

Front Microbiol 2018 20;9:2804. Epub 2018 Nov 20.

Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Ohio State University, Columbus, OH, United States.

Biofilm formation is a common strategy utilized by bacterial pathogens to establish persistence in a host niche. serovar Typhi, the etiological agent of Typhoid fever, relies on biofilm formation in the gallbladder to chronically colonize asymptomatic carriers, allowing for transmission to uninfected individuals. serovar Typhimurium utilizes biofilms to achieve persistence in human and animal hosts, an issue of both clinical and agricultural importance. Read More

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November 2018

First-in-human phase 1 study of novel dUTPase inhibitor TAS-114 in combination with S-1 in Japanese patients with advanced solid tumors.

Invest New Drugs 2018 Dec 4. Epub 2018 Dec 4.

Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.

Background This first-in-human phase 1 study assessed the safety of TAS-114, a novel deoxyuridine triphosphatase inhibitor, combined with S-1 to determine its maximum tolerated dose (MTD) and recommended dose (RD). Methods In this dose-escalation study with a 3 + 3 design, TAS-114 and S-1 were concurrently administered orally under fasting conditions at 5-240 mg/m and 30-36 mg/m, respectively, in patients with advanced solid tumors. Safety, efficacy, and pharmacokinetics (PK) were evaluated. Read More

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December 2018

Gallbladder varices in a pediatric patient after roux-en-Y gastric bypass.

J Pediatr Surg 2018 Dec 25;53(12):2511-2513. Epub 2018 Aug 25.

Department of Pediatric Surgery, University of Arkansas for Medical Sciences, Little Rock, AR.

This is a case with associated radiologic images for a pediatric patient who developed portomesenteric and splenic vein thrombosis (PMSVT) after Roux-en-Y gastric bypass with subsequent development of portal cavernoma and gallbladder varices (GBV). This case highlights both the importance of post-operative prophylactic anti-coagulation after gastric bypass and detailed imaging following a diagnosis of PMSVT. This case is relevant for pediatric surgeons as they are performing this operation more frequently with the increase in pediatric obesity. Read More

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December 2018
1 Read

National Failure of Surgical Staging for T1b Gallbladder Cancer.

Ann Surg Oncol 2018 Nov 29. Epub 2018 Nov 29.

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Michael E. DeBakey VA Medical Center, Houston, TX, USA.

Background: Current guidelines recommend radical cholecystectomy with regional lymphadenectomy (RC-RL) for patients with T1b gallbladder cancer (GBC). However, the extent to which these guidelines are followed is unclear. This study aimed to evaluate current surgical practices for T1b GBC and their implications for overall management strategies and associated outcomes. Read More

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November 2018
2 Reads

A "reappearance" of gallbladder in a liver transplant recipient.

Hepatobiliary Surg Nutr 2018 Oct;7(5):412-413

Department of General and Liver/Pancreas Transplant Surgery, University of Montpellier-College of Medicine, Hôpital Saint Eloi, Montpellier, France.

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October 2018
1 Read

Neoplastic Meningitis: A Study from a Tertiary Care Hospital from Coastal India.

J Cytol 2018 Oct-Dec;35(4):255-259

Department of Cellular Pathology, Leighton Hospital, Crewe, Cheshire, United Kingdom.

Introduction: Neoplastic involvement of cerebrospinal fluid (CSF) secondary to known or unknown primaries elsewhere is a poor prognostic factor and is equivalent to stage IV disease.

Aim: The aim of the study is to analyse the cytological features of neoplastic meningitis in a tertiary care center.

Materials And Methods: A retrospective study of 400 consecutive CSF samples was done in the cytology laboratory of our hospital. Read More

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December 2018
1 Read

EUS-guided gallbladder polyp resection: A new method for treatment of gallbladder polyps.

Hepatobiliary Pancreat Dis Int 2018 Nov 22. Epub 2018 Nov 22.

Department of Gastroenterology and Hepatology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China. Electronic address:

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November 2018
1 Read

EBV as a potential risk factor for hepatobiliary system cancer: A meta-analysis with 918 cases.

Pathol Res Pract 2018 Nov 2. Epub 2018 Nov 2.

Department of General Surgery, The Second Affiliated Hospital of Guangxi Medical University, NO.166. DaxueXi Rd, Nanning, Guangxi Zhuang Autonomous Region, 530021, PR China. Electronic address:

Objectives: Hepatobiliary system cancer, which includes hepatocellular carcinoma (HCC), cholangiocarcinoma, and gallbladder carcinoma, has an increase of incidence and mortality due to various risk factors. Epstein-Barr virus (EBV) is associated with various types of lymphomas and carcinomas, which is also acknowledged as the first-discovered human tumor virus. Despite this, there is no systematic analysis about the relationship between the infection of EBV and hepatobiliary system cancer. Read More

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November 2018

MiR-1-5p is down-regulated in gallbladder carcinoma and suppresses cell proliferation, migration and invasion by targeting Notch2.

Pathol Res Pract 2018 Oct 22. Epub 2018 Oct 22.

Emergency Trauma Surgery, BinZhou Medical University Hospital, Binzhou, Shandong, 256600, China. Electronic address:

Background: Numerous studies have demonstrated that aberrant microRNAs (miRNAs) are involved in tumorigenesis and tumor progression. Nevertheless, the precise role of miR-1-5p in gallbladder carcinoma cell growth and metastasis remains not fully revealed.

Material And Methods: The levels of miR-1-5p were detected in gallbladder carcinoma tissues and cell lines using qRT-PCR method. Read More

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October 2018
2 Reads

Strategy for discriminating cholesterol and premalignancy in polypoid lesions of the gallbladder: a single-centre, retrospective cohort study.

ANZ J Surg 2018 Nov 29. Epub 2018 Nov 29.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Background: The present study aimed to assess the risk factors of cholesterol and premalignancy in polypoid lesions of the gallbladder (PLGs) and to establish an appropriate treatment strategy.

Methods: Data from patients who underwent cholecystectomy at the First Affiliated Hospital, School of Medicine, Zhejiang University, between January 2011 and July 2017, were collected retrospectively.

Results: A total of 1561 patients were included in the present study. Read More

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November 2018
1 Read

Radiofrequency ablation of liver cancers adjacent to the gallbladder without gallbladder isolation under contrast-enhanced ultrasound monitoring: a preliminary study.

Int J Hyperthermia 2018 Nov 29:1-6. Epub 2018 Nov 29.

a Department of Medical Ultrasonics, Guangdong Key Laboratory of Liver Disease Research , The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.

Purpose: The purpose of this study was to investigate the feasibility, safety and efficacy of intra-procedural contrast-enhanced ultrasound (CEUS) monitoring of the radiofrequency ablation (RFA) of liver cancers adjacent to gallbladder (GB) without GB isolation.

Materials And Methods: From May 2016 to July 2017, patients with liver cancers adjacent to GB (≤10 mm) who intended to undergo ultrasound-guided RFA without GB isolation in our hospital were prospectively enrolled. During the RFA procedures, CEUS was employed to evaluate the therapeutic response and the perfusion of the intact GB wall. Read More

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November 2018
2 Reads

Importance of routine histopathological examination of a gallbladder surgical specimen: Unexpected gallbladder cancer.

J Cancer Res Ther 2018 Oct-Dec;14(6):1325-1329

Department of General Surgery, Faculty of Medicine, Adıyaman University, Adıyaman, Turkey.

Introduction: Cholecystectomy performed for benign diseases of the gallbladder is important for the diagnosis of gallbladder cancer. This is done by pathological examination of the removed specimens for patients with no detected or suspected complications before surgery. Although some centers undertake selective approaches for histopathological examination of gallbladder specimens, many centers perform this examination routinely. Read More

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November 2018
3 Reads

A Gallbladder-Based Enterohepatic Circulation Model for Pharmacokinetic Studies.

Eur J Drug Metab Pharmacokinet 2018 Nov 28. Epub 2018 Nov 28.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.

Background And Objectives: Strategies for modeling the enterohepatic circulation (EHC) process reported in the literature vary; however, gallbladder-based models currently provide the best physiological representation of the process. Regardless, the addition of a gallbladder to the model does not fully depict the physiology of EHC. A more physiological gallbladder-based EHC model is needed. Read More

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November 2018
7 Reads

The "honeycomb" gallbladder.

Abdom Radiol (NY) 2018 Nov 28. Epub 2018 Nov 28.

Department of Radiology, Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC, 27157, USA.

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November 2018
1 Read

Stepwise evaluation of liver sectors and liver segments by endoscopic ultrasound.

World J Gastrointest Endosc 2018 Nov;10(11):326-339

Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute, Lucknow 226014, Uttar Pradesh, India.

The liver has eight segments, which are referred to by numbers or by names. The numbering of the segments is done in a counterclockwise manner with the liver being viewed from the inferior surface, starting from Segment I (the caudate lobe). Standard anatomical description of the liver segments is available by computed tomographic scan and ultrasonography. Read More

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November 2018
2 Reads

Acute acalculous cholecystitis in children.

World J Gastroenterol 2018 Nov;24(43):4870-4879

Department of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.

Acute acalculous cholecystitis (AAC) is the inflammatory disease of the gallbladder in the absence of gallstones. AAC is estimated to represent at least 50% to 70% of all cases of acute cholecystitis during childhood. Although this pathology was originally described in critically ill or post-surgical patients, most pediatric cases have been observed during several infectious diseases. Read More

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November 2018
4 Reads

A 52 Years Old Male Presented With Acute Kidney Injury with Hepatitis after Taking Fish Gallbladder.

Authors:
O F Miah F A Dowel

Mymensingh Med J 2018 Oct;27(4):866-868

Dr Mohammad Omar Faruque Miah, Senior Clinical Pathologist, Department of Pathology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh.

A 52 years old male was admitted at National Institute of Kidney Diseases & Urology, Dhaka, Bangladesh on 16th September 2016 with the history of oliguria, nausea, vomiting & swelling of both legs following consumption of rohu fish gall bladder for the permanent remedy of recurrent abdominal discomfort. He was admitted and received antiemetic, proton pump inhibitor. He had azotemia & underwent urgent haemodialysis (HD). Read More

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October 2018

Evaluation of Preoperative Ultrasonography in Gall Stone Disease to Predict Technical Difficulties during Laparoscopic Cholecystectomy.

Mymensingh Med J 2018 Oct;27(4):757-763

Dr Md Monoarul Islam Talukdar, Resident Surgeon (Surgery), Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh; E-mail:

Laparoscopic cholecystectomy is the gold standard in the treatment of gallstones. This study was carried out to determine the technical difficulties that can be encountered during laparoscopic cholecystectomy and to evaluate the role of ultrasonography in identifying patients at risk of conversion returning to open surgery. The objective of this study was to evaluate the efficacy of preoperative ultrasonography in assessing technical difficulty faced during laparoscopic cholecystectomy in gallstone disease. Read More

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October 2018
1 Read

Surgical ultrasonography at the bedside: a comparison of surgical trainees with trained sonographers for symptomatic cholelithiasis - a first Australian experience.

ANZ J Surg 2018 Nov 28. Epub 2018 Nov 28.

Upper Gastrointestinal Surgery Unit, Liverpool Hospital, Sydney, New South Wales, Australia.

Background: Symptomatic cholelithiasis accounts for a significant burden of emergency general surgical presentations in Australia and the Western population. Access to hepatobiliary ultrasonography to facilitate diagnosis can lead to delays in timely treatment. Surgical ultrasonography at the bedside (SUB) can mitigate this barrier to patient care. Read More

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November 2018

Comet tail artifact on ultrasonography: is it a reliable finding of benign gallbladder diseases?

Ultrasonography 2018 Oct 3. Epub 2018 Oct 3.

Department of Radiology, Eulji University Hospital, Daejeon, Korea.

Purpose: The aim of this study was to evaluate whether the comet tail artifact on ultrasonography can be used to reliably diagnose benign gallbladder diseases.

Methods: This retrospective study reviewed the clinical findings, imaging findings, preoperative ultrasonographic diagnoses, and pathological diagnoses of 150 patients with comet tail artifacts who underwent laparoscopic cholecystectomy with pathologic confirmation. The extent of the involved lesion was classified as localized or diffuse, depending on the degree of involvement and the anatomical section of the gallbladder that was involved. Read More

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October 2018
2 Reads

Ezetimibe for the prevention of cardiovascular disease and all-cause mortality events.

Cochrane Database Syst Rev 2018 Nov 19;11:CD012502. Epub 2018 Nov 19.

Pharmacy Department, First Affiliated Hospital of Third Military Medical University (Army Medical University), 30 Gaotanyan Street, Shapingba District, Chongqing, China, 400038.

Background: Cardiovascular disease (CVD) remains an important cause of mortality and morbidity, and high levels of blood cholesterol are thought to be the major modifiable risk factors for CVD. The use of statins is the preferred treatment strategy for the prevention of CVD, but some people at high-risk for CVD are intolerant to statin therapy or unable to achieve their treatment goals with the maximal recommended doses of statin. Ezetimibe is a selective cholesterol absorption inhibitor, whether it has a positive effect on CVD events remains uncertain. Read More

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November 2018
4 Reads

Differential diagnosis of gallbladder polypoid lesions using contrast-enhanced ultrasound.

Abdom Radiol (NY) 2018 Nov 26. Epub 2018 Nov 26.

Division of Gastroenterology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.

Purpose: The purpose of the study is to evaluate the utility of contrast-enhanced ultrasound (CEUS) for the differential diagnosis of gallbladder polypoid lesions (GPLs).

Methods: Thirty-six patients with GPLs (17 with gallbladder cancer, 19 with benign polyps) who underwent CEUS were enrolled in the study. The mean age of patients was 65. Read More

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November 2018

HISTOPATHOLOGIC FINDINGS IN FREE-RANGING CALIFORNIA HUMMINGBIRDS, 1996-2017.

J Wildl Dis 2018 Nov 26. Epub 2018 Nov 26.

1   Veterinary Diagnostic Laboratory, College of Veterinary Medicine, 4125 Beaumont Road, Michigan State University, Lansing, Michigan 48910, USA.

A histopathologic study of free-ranging hummingbirds in California was performed to identify mortality trends. Tissues from 61 wild hummingbirds representing five native California species collected by the San Diego Zoo from 1996 to 2016 or the Lindsay Wildlife Experience from 2015 to 2017 were histologically examined. Birds were either found dead or moribund at the time of submission or were euthanized due to unresolvable health issues. Read More

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November 2018
3 Reads

Gallbladder volvulus-acute cholecystitis 'with a twist'.

Authors:
James Aljoe

J Surg Case Rep 2018 Nov 19;2018(11):rjy303. Epub 2018 Nov 19.

General Surgery, Manly Hospital, 150 Darley Road Manly Sydney, Manly, New South Wales, Australia.

A Caucasian 92-year-old female was admitted to hospital with acute epigastric pain associated with vomiting. Initial investigations revealed mildly raised inflammatory markers, normal liver function tests but a markedly distended gallbladder with prominent wall thickening. The patient was managed with intravenous antibiotics for acute cholecystitis but deteriorated significantly on Day 2 of admission. Read More

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November 2018
1 Read

Gallbladder Stone Disease Is Associated with an Increased Risk of Migraines.

J Clin Med 2018 Nov 21;7(11). Epub 2018 Nov 21.

Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taichung 404, Taiwan.

Several pathophysiological mechanisms are shared in both gallbladder stone disease (GSD) and migraines. We assessed the migraine risk for patients diagnosed with GSD. We identified 20,427 patients who were diagnosed with GSD between 2000 and 2011 from Taiwan's National Health Insurance Research Database (NHIRD) as the study cohort. Read More

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November 2018

Relationship of Gallbladder Diseases with Sociodemographic Characteristics, Lifestyle, and Chronic Diseases in Northeastern China.

Int J Environ Res Public Health 2018 Nov 21;15(11). Epub 2018 Nov 21.

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.

Background: Gallbladder diseases are common in Jilin, China. However, there have been few previous studies on this disease. Our study used the chronic disease database in Jilin Province to study the factors correlated with gallbladder diseases. Read More

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November 2018

A case report: Feasibility of a near infrared ray vision system (Photo dynamic eye®) for the postoperative ischemic complication of gallbladder carcinoma.

Int J Surg Case Rep 2018 Nov 13;53:312-315. Epub 2018 Nov 13.

Japan Seafares Relief Association Moji Ekisaikai Hospital, Japan.

Introduction: Radical resection with or without preserving extra-hepatic bile duct has shown similar prognoses for gallbladder carcinoma (GB ca), although aggressive resection is essential. In preserving bile duct, ischemic complications are serious, life-threatening serious problems. Correct evaluation of the blood flow to the biliary tract is crucial. Read More

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November 2018
5 Reads

The impact of 2D cine MR imaging parameters on automated tumor and organ localization for MR-guided real-time adaptive radiotherapy.

Phys Med Biol 2018 Nov 22;63(23):235005. Epub 2018 Nov 22.

Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom.

2D cine MR imaging may be utilized to monitor rapidly moving tumors and organs-at-risk for real-time adaptive radiotherapy. This study systematically investigates the impact of geometric imaging parameters on the ability of 2D cine MR imaging to guide template-matching-driven autocontouring of lung tumors and abdominal organs. Abdominal 4D MR images were acquired of six healthy volunteers and thoracic 4D MR images were obtained of eight lung cancer patients. Read More

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November 2018
3 Reads

Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer.

Cancer Manag Res 2018 30;10:5101-5112. Epub 2018 Oct 30.

Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China,

Background: PIM1, a serine/threonine kinase, plays an essential role in tumorigenesis of multiple types of tumors. However, the expression pattern and functions of PIM1 in gallbladder cancer (GBC) remain largely unknown.

Materials And Methods: Immunohistochemistry, quantitative real-time PCR, and western blot analysis were performed to measure the expression of PIM1. Read More

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October 2018
3 Reads

Bio-guided fractionation and iron chelating activity of agricultural residues.

Drug Discov Ther 2018 ;12(5):299-303

Department of Pharmacognosy, Faculty of Pharmacy, Sohag University.

Iron overload is implicated in many disorders in the body such as heart failure, liver cirrhosis and fibrosis, gallbladder disorders, diabetes, arthritis, depression, infertility, and cancer. Even though synthetic chelating agents are available, they have several limitations such as poor oral bioavailability, short plasma half-life, high cost and numerous side effects. Therefore, the aim of this study is using agricultural residues as sources for alternative efficient, benign, and economic iron chelators of natural origin. Read More

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January 2018
2 Reads

Percutaneous Cholecystostomy in Acute Cholecystitis-Predictors of Recurrence and Interval Cholecystectomy.

J Surg Res 2018 Dec 3;232:539-546. Epub 2018 Aug 3.

Department of Surgery, Lahey Hospital and Medical Center, Burlington, Massachusetts.

Background: Percutaneous cholecystostomy (PC) tube is a preferred option in acute cholecystitis for patients who are high risk for cholecystectomy (CCY). There are no evidence-based guidelines for patient care after PC. We identified the predictors of disease recurrence and successful interval CCY. Read More

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December 2018
2 Reads

Circulating CEA-dNLR score predicts clinical outcome of metastatic gallbladder cancer patient.

Authors:
Jing-Hui Du Jun Lu

J Clin Lab Anal 2018 Nov 21:e22684. Epub 2018 Nov 21.

Department of Clinical Laboratory, Longyan People Hospital, Longyan, China.

Background: Cancer-related inflammation promotes gallbladder tumorigenesis and metastasis of gallbladder cancer (mGBC). The levels of circulating inflammatory-related cell and protein as well as the ratios of them may imply the severity of chronic inflammation in GBC patients, and all of them are candidate prognostic biomarkers for mGBC.

Materials And Methods: In our study, pre-treatment circulating immune cell, fibrinogen (Fib), albumin (Alb), and pre-albumin (pAlb) were detected in 220 mGBC patients, and we calculated neutrophil-to-lymphocyte ratio (NLR), derived neutrophil-to-lymphocyte ratio (dNLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), Alb-to-Fib ratio (AFR), and Fib-to-pAlb ratio (FPR) replying on the detection. Read More

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November 2018
9 Reads

Simultaneous osteosarcoma and adenocarcinoma of the gallbladder: A rare case report and literature review.

Turk J Gastroenterol 2018 Nov 20. Epub 2018 Nov 20.

Department of General Surgery, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.

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November 2018
5 Reads

Biliary Taeniasis with Cholecystitis: An Unusual Case of Infection with a Literature Review.

Am J Trop Med Hyg 2018 Nov 19. Epub 2018 Nov 19.

Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Taeniasis is a cosmopolitan helminthic disease caused by species, which included , , and . These parasites typically infect the small intestine, but cases of aberrant migration have been reported. We treated a 70-year-old man who presented with vomiting and colicky abdominal pain. Read More

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November 2018
7 Reads

Is right-sided ligamentum teres hepatis always accompanied by left-sided gallbladder? Case reports and literature review.

Insights Imaging 2018 Nov 19. Epub 2018 Nov 19.

Department of Radiology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Beitou District, Taipei, 112, Taiwan, Republic of China.

Right-sided ligamentum teres (RSLT) hepatis is a rare anatomical variant in which the fetal umbilical vein is connected to the right paramedian trunk of the portal vein. Despite its rarity, it is crucial for surgeons and intervention specialists because of its frequent association with intrahepatic vascular and biliary anomalies. Inattention to these anomalies before intervention, especially living-donor liver transplantation, can have life-threatening consequences. Read More

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November 2018
2 Reads

Elective cholecystectomy as a rare presentation of metastatic breast cancer.

J Surg Case Rep 2018 Nov 13;2018(11):rjy301. Epub 2018 Nov 13.

Surgical Department, Centro Hospitalar Entre Douro e Vouga, E.P.E., Santa Maria da Feira, Portugal.

Cholecystectomy leads, occasionally, to the diagnosis of subclinical primary carcinomas and rarely metastatic tumors. The authors report the diagnosis of gallbladder metastasis after an elective cholecystectomy for symptomatic cholelithiasis. Histological examination disclosed a metastasis from a lobular breast carcinoma. Read More

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November 2018
5 Reads

Genetic landscape of gallbladder cancer: Global overview.

Mutat Res 2018 Oct - Dec;778:61-71. Epub 2018 Aug 23.

Laboratory Oncology Unit, Rotary Cancer Center, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Gallbladder cancer (GBC) is a rare malignancy of biliary tract cancer (BTC), characterized by late presentation and poor prognosis. It exhibits wide geographical as well as ethnical variations. So, diverse epidemiology along with etiological factors have been discussed in the current article. Read More

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August 2018
2 Reads
3.680 Impact Factor