55,182 results match your criteria Gait & Posture [Journal]


Gait initiation and partial body weight unloading for functional improvement in post-stroke individuals.

Gait Posture 2018 Dec 6;68:305-310. Epub 2018 Dec 6.

Institute of Physical Activity and Sport Sciences, Cruzeiro do Sul University, São Paulo, SP, Brazil. Electronic address:

Background: To better understand gait initiation in individuals with stroke and suggest possible training strategies, we compared the gait initiation of individuals with stroke and age-matched controls, and we examined the influence of different amounts of body weight support (BWS) during the execution of gait initiation in individuals with stroke.

Materials And Methods: Twelve individuals with stroke and 12 age-matched controls initiated gait after a verbal command at a self-selected and comfortable speed, and individuals with stroke also initiated gait wearing a harness with 0%, 15%, and 30% of BWS. Length and velocity of the first step, distance between heels, and weight bearing in both lower limbs in the initial position were calculated. Read More

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December 2018

Idiopathic toe walking-A follow-up survey of gait analysis assessment.

Gait Posture 2018 Dec 6;68:300-304. Epub 2018 Dec 6.

School of Physiotherapy, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, Ireland.

Background: Toe-walking is a normal variant in children up to 3 years of age but beyond this a diagnosis of idiopathic toe-walking (ITW) must be considered. ITW is an umbrella term that covers all cases of toe-walking without any diagnosed underlying medical condition and before assigning these diagnosis potential differential diagnoses such as cerebral palsy, peripheral neuropathy, spinal dysraphism and myopathy must be ruled out. Gait laboratory assessment (GLA) is thought to be useful in the evaluation of ITW, and kinematic, kinetic and electromyography features associated with ITW have been described. Read More

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December 2018

The neural correlates of discrete gait characteristics in ageing: A Structured Review.

Neurosci Biobehav Rev 2018 Dec 12. Epub 2018 Dec 12.

Institute of Neuroscience, Newcastle University Institute of Ageing, Newcastle Upon Tyne, UK; Newcastle Upon Tyne Hospital NHS Foundation Trust, UK. Electronic address:

Gait is complex, described by diverse characteristics underpinned by widespread central nervous system networks including motor and cognitive functions. Despite this, neural substrates of discrete gait characteristics are poorly understood, limiting understanding of gait impairment in ageing and disease. This structured review aims to map gait characteristics, defined from a pre-specified model reflecting independent gait domains, to brain imaging parameters in older adults. Read More

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December 2018
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From deep learning to transfer learning for the prediction of skeletal muscle forces.

Authors:
Tien Tuan Dao

Med Biol Eng Comput 2018 Dec 14. Epub 2018 Dec 14.

Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de recherche Royallieu, Compiègne Cedex, France.

Skeletal muscle forces may be estimated using rigid musculoskeletal models and neural networks. Neural network (NN) approach has the advantages of real-time estimation ability and promising prediction accuracy. However, most of the developed NN models are based on conventional feedforward NNs, which do not take dynamic temporal relationships of the muscle force profiles into consideration. Read More

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December 2018

Lean mass and lower limb muscle function in relation to hip strength, geometry and fracture risk indices in community-dwelling older women.

Osteoporos Int 2018 Dec 14. Epub 2018 Dec 14.

Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

In a population-based sample of British women aged over 70 years old, lean mass and peak lower limb muscle force were both independently associated with hip strength and fracture risk indices, thereby suggesting a potential benefit of promoting leg muscle strengthening exercise for the prevention of hip fractures in postmenopausal women.

Introduction: To investigate cross-sectional associations of lean mass and physical performance, including lower limb muscle function, with hip strength, geometry and fracture risk indices (FRIs) in postmenopausal women.

Methods: Data were from the Cohort of Skeletal Health in Bristol and Avon. Read More

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December 2018

Efficacy and efficiency of multivariate linear regression for rapid prediction of femoral strain fields during activity.

Med Eng Phys 2018 Dec 11. Epub 2018 Dec 11.

Medical Device Research Institute, College of Science and Engineering, Flinders University, Clovelly Park, Tonsley, Adelaide, SA, Australia.

Multivariate Linear Regression-based (MLR) surrogate models were explored to reduce the computational cost of predicting femoral strains during normal activity in comparison with finite element analysis. The musculoskeletal model of one individual, the finite-element model of the right femur, and experimental force and motion data for normal walking, fast walking, stair ascent, stair descent, and rising from a chair were obtained from a previous study. Equivalent Von Mises strain was calculated for 1000 frames uniformly distributed across activities. Read More

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December 2018

Walking speed and spatiotemporal step mean measures are reliable during feedback-controlled treadmill walking; however, spatiotemporal step variability is not reliable.

J Biomech 2018 Dec 7. Epub 2018 Dec 7.

University of Nebraska - Omaha, Omaha, NE, United States. Electronic address:

The purpose of the study was to compare the effects of a feedback-controlled treadmill (FeedbackTM) to a traditional fixed-speed treadmill (FixedTM) on spatiotemporal gait means, variability, and dynamics. The study also examined inter-session reliability when using the FeedbackTM. Ten young adults walked on the FeedbackTM for a 5-minute familiarization followed by a 16-minute experimental trial. Read More

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December 2018

A prediction method of speed-dependent walking patterns for healthy individuals.

Gait Posture 2018 Dec 5;68:280-284. Epub 2018 Dec 5.

Federal University of ABC, Neuroscience and Biomedical Engineering Programs, São Bernardo do Campo, São Paulo, Brazil. Electronic address:

Background: Gait speed is one of the main biomechanical determinants of human movement patterns. However, in clinical gait analysis, the effect of gait speed is generally not considered, and people with disabilities are usually compared with able-bodied individuals even though disabled people tend to walk slower.

Research Questions: This study proposes a simple way to predict the gait pattern of healthy individuals at a specific speed. Read More

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December 2018

Multi-segment spine kinematics: Relationship with dance training and low back pain.

Gait Posture 2018 Dec 4;68:274-279. Epub 2018 Dec 4.

Centre for Sport Research, School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Highway, Burwood, VIC 3125, Australia; Sport Performance Research Institute New Zealand, Auckland University of Technology, 17 Antares Place, Rosedale, Auckland 0632, New Zealand. Electronic address:

Background: Spine posture, range of motion (ROM) and movement asymmetry can contribute to low back pain (LBP). These variables may have greater impact in populations required to perform repetitive spine movements, such as dancers; however, there is limited evidence to support this.

Research Question: What is the influence of dance and LBP on spinal kinematics?

Methods: In this cross-sectional study, multi-segment spinal kinematics were examined in 60 female participants, including dancers (n = 21) and non-dancers (n = 39) with LBP (n = 33) and without LBP (n = 27). Read More

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December 2018
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Kinematics reduction applied to the comparison of highly-pronated, normal and highly-supinated feet during walking.

Gait Posture 2018 Dec 6;68:269-273. Epub 2018 Dec 6.

Departamento de Ingeniería Mecánica y Construcción, Universitat Jaume I, Av. Vicent Sos Baynat, s/n, 12071, Castellón, Spain. Electronic address:

Background: Kinematic analysis could help to study how variations in the static foot posture affect lower limb biomechanical function. The analysis of foot kinematics is complex because it involves managing the time-dependent joint angles in different joints and in all three planes of motion. But it could be simplified if joint angles are coordinated. Read More

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December 2018

6th vital sign app: Testing validity and reliability for measuring gait speed.

Gait Posture 2018 Dec 5;68:264-268. Epub 2018 Dec 5.

Kinesiology Department, California State University, Monterey Bay, 100 Campus Center, Seaside, CA, 93955, USA. Electronic address:

Background: Gait speed tests are useful predictors of different health outcomes in people. These tests can be administered by the convenience of one's smartphone.

Research Question: Is the 6th Vital Sign app valid and reliable for measuring gait speed?

Methods: The study used a prospective test-retest design. Read More

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December 2018

The relationship between trunk position sense and postural control in ataxic individuals.

Gait Posture 2018 Dec 6;68:258-263. Epub 2018 Dec 6.

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey.

Background: The proprioceptive system plays a role in the maintenance of postural control more than the visual and vestibular systems in ataxic patients with postural control disorders, but the relationship between trunk proprioception and postural control has not been sufficiently investigated yet. This relationship can provide a different perspective to the ataxia rehabilitation.

Research Question: This study aimed to examine the relationship between trunk position sense and postural control in ataxic individuals by comparing them to healthy individuals. Read More

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December 2018

Effects of heel height and high-heel experience on foot stability during quiet standing.

Gait Posture 2018 Dec 5;68:252-257. Epub 2018 Dec 5.

Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hunghom, Hong Kong. Electronic address:

Background: The use of high-heeled shoes (HHS) introduces instability into the wearer's balance system but how high-heel experience might influence standing balance is less examined in literature.

Research Question: (1) Does foot stability decrease in both the antero-posterior (AP) and medial-lateral (ML) directions with increasing heel height during quiet standing? (2) Does high-heel experience improve the wearer's foot stability during quiet standing in high-heeled conditions?

Methods: Twenty-four young females (12 regular and 12 non-regular HHS wearers) were recruited to perform quiet standing while wearing shoes with heel heights of 1 cm, 5 cm, 8 cm and 10 cm. The effects of heel height on the mean center of pressure (COP), their variability (standard deviations) and mean COP velocities in both the AP and ML directions were analysed by one-way repeated measures ANOVA and Bonferroni post-hoc test. Read More

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December 2018

Identification of knee gait waveform pattern alterations in individuals with patellofemoral pain using fast Fourier transform.

PLoS One 2018 14;13(12):e0209015. Epub 2018 Dec 14.

Division of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, United States of America.

Patellofemoral pain (PFP) is one of the most common overuse injuries of the knee. Previous research has found that individuals with PFP exhibit differences in peak hip kinematics; however, differences in peak knee kinematics, where the pain originates, are difficult to elucidate. To better understand the mechanism behind PFP, we sought to characterize differences in knee gait kinematic waveform patterns in individuals with PFP compared to healthy individuals using fast Fourier transform (FFT). Read More

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December 2018

Does Hands-on Guarding Influence Performance on the Functional Gait Assessment?

J Geriatr Phys Ther 2018 Dec 12. Epub 2018 Dec 12.

CoxHealth, Springfield, Missouri.

Background And Purpose: An accurate fall risk assessment is an important component of fall prevention, though a fall could occur during testing. To minimize this risk, different guarding methods are used, though there is disagreement regarding the optimal method. The purpose of this study was to compare the effect of 2 guarding methods, contact guarding (CG) and standby guarding (SG), on performance during the Functional Gait Assessment (FGA). Read More

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December 2018

Symptom Burden Among Community-Dwelling Older Adults in the United States.

J Am Geriatr Soc 2018 Dec 12. Epub 2018 Dec 12.

Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington.

Objectives: To determine the prevalence and impact of common co-occurring symptoms among community-dwelling older adults in the United States.

Design: The National Health and Aging Trends Study is a nationally representative, prospective study with annual data collection between 2011 and 2017.

Setting: Community-based, in-person interviews (survey response rates, 71%-96%). Read More

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December 2018

Intuitive Clinician Control Interface for a Powered Knee-Ankle Prosthesis: A Case Study.

IEEE J Transl Eng Health Med 2018 23;6:2600209. Epub 2018 Nov 23.

Department of BioengineeringThe University of Texas at DallasRichardsonTX75080USA.

This paper presents a potential solution to the challenge of configuring powered knee-ankle prostheses in a clinical setting. Typically, powered prostheses use impedance-based control schemes that contain several independent controllers which correspond to consecutive periods along the gait cycle. This control strategy has numerous control parameters and switching rules that are generally tuned by researchers or technicians and not by a certified prosthetist. Read More

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November 2018

Evaluation of a method to scale muscle strength for gait simulations of children with cerebral palsy.

J Biomech 2018 Nov 29. Epub 2018 Nov 29.

Department of Mechanical Engineering, Colorado School of Mines, Golden, CO 80401, United States. Electronic address:

Cerebral palsy (CP) is a neurological disorder that results in life-long mobility impairments. Musculoskeletal models used to investigate mobility deficits for children with CP often lack subject-specific characteristics such as altered muscle strength, despite a high prevalence of muscle weakness in this population. We hypothesized that incorporating subject-specific strength scaling within musculoskeletal models of children with CP would improve accuracy of muscle excitation predictions in walking simulations. Read More

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November 2018

Spatiotemporal Gait Analysis and Lower Limb Functioning in Foot Dystonia Treated with Botulinum Toxin.

Toxins (Basel) 2018 Dec 12;10(12). Epub 2018 Dec 12.

Head John Walsh Centre for Rehabilitation Research, Sydney Medical School, University of Sydney, Sydney 2006, Australia.

Foot dystonia (FD) is a disabling condition causing pain, spasm and difficulty in walking. We treated fourteen (14) adult patients experiencing FD with onabotulinum toxin A injection into the dystonic foot muscles. We analyzed the spatiotemporal gait utilizing the GaitRite system pre- and 3 weeks post-botulinum toxin injection along with measuring dystonia by the Fahn⁻Marsden Dystonia Scale (FMDS), pain by the Visual Analog Scale (VAS) and other lower limb functional outcomes such as gait velocity, the Berg Balance Scale (BBS), the Unified Parkinson's Disease Rating Scale⁻Lower Limb Score (UPDRS⁻LL), the Timed Up and Go (TUG) test and the Goal Attainment Scale (GAS). Read More

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December 2018

Fat-Free Mass and the Balance Error Scoring System Predict an Appropriate Maximal Load in the Unilateral Farmer's Walk.

Sports (Basel) 2018 Dec 8;6(4). Epub 2018 Dec 8.

Department of Exercise and Rehabilitative Sciences, Slippery Rock University, 337 Patterson Hall, Slippery Rock, PA 16057, USA.

This study quantified and compared unilateral farmer's walk (UFW) performance in recreationally active males and females, and determined if additional variables allowed for the prediction of a maximal safe load. Anthropometric (height, body weight (BW), body mass index, body fat percentage, fat-free mass (FFM), and fat mass), muscular endurance (maximal duration side bridge), and balance (Balance Error Scoring System (BESS)) tests were completed. Participants performed a series of 20 s UFW trials (non-dominant side) at a cadence of 66 beats/min. Read More

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December 2018

Complete clinical and functional recovery following low-dose methotrexate related paraparesis in a patient with compound c.1298A>C AND c.677C>T MTHFR polymorphism: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13350

Molecular Medicine and Genetics, Azienda Ospedaliera Universitaria Senese, Siena and Clinical Genetics Usl Sudest, Misericordia Hospital, Grosseto, Italy.

Rationale: The mechanisms of action of MTX (methotrexate) in the treatment of RA (rheumatoid arthritis) and PsA (psoriatic arthritis) is related to its antifolic activity, due to the high affinity for enzymes that require folate cofactors as dihydrofolate reductase and to the anti-inflammatory activity derivated from the inhibition of thymidylate synthetase that leads to the over-production of adenosine.

Patient Concerns: Our patient was a 41-year-old female, affected by PsA in treatment since 2 years with low-dose methylprednisolone and low-dose subcutaneous MTX. The treatment was effective. Read More

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December 2018

Using Smart Socks to Detect Step-count at Slow Walking Speeds in Healthy Adults.

Int J Sports Med 2018 Dec 13. Epub 2018 Dec 13.

School of Allied Health Sciences, Griffith University, Gold Coast, Australia.

We examined the accuracy of Smart Socks - a device that measures foot pressure during gait for detecting step-count across various walking speeds. Thirty-six participants (17 men; 19 women) wore Smart Socks (Sock), a pedometer (Pedometer), and a smartphone with a commercially available Phone Application (Phone) pedometer to measure step-count during 3-min of treadmill or over-ground walking at 1.3, 2. Read More

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December 2018

The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders.

Eur Spine J 2018 Dec 12. Epub 2018 Dec 12.

Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.

Purpose: To evaluate the correlations between back muscle strength, trunk muscle mass, and sarcopenia-related parameters in patients with spinal disorders.

Methods: This cross-sectional observational study included 230 consecutive patients with spinal disorders who visited our outpatient clinic (age range 65-92 years). We measured back muscle strength, handgrip strength, gait speed, and appendicular and trunk skeletal muscle mass using bioimpedance analysis. Read More

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December 2018

[The association of limited health literacy and risk of arterial stiffness in community-dwelling older adults].

Nihon Ronen Igakkai Zasshi 2018 ;55(4):605-611

Department of Liberal arts and Sciences, Toyama Prefectural University.

Aim: This study aimed to investigate the effects of limited health literacy on arterial stiffness measured by the cardio-ankle vascular index (CAVI) in community-dwelling older adults.

Methods: A total of 288 older adults (mean age, 72.4 years, men, n = 99) participated. Read More

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January 2018

Age and time course of long-term motor and nonmotor complications in Parkinson disease.

Neurology 2018 Dec 12. Epub 2018 Dec 12.

From Université Lyon (S.P., T.D., C.L., E.M., E.B., S.T.), Institut des Sciences Cognitives-Marc Jeannerod, CNRS, UMR 5229, Bron; Hospices Civils de Lyon (S.P., T.D., C.C., C.L., E.M., H.M., E.B., S.T.), Hôpital Neurologique Pierre Wertheimer, Service de Neurologie C, Centre Expert Parkinson, Bron; Université Lyon (C.L., E.B., D.M.-B., S.T.), Faculté de Médecine Lyon Sud Charles Mérieux, Oullins; Hospices Civils de Lyon (D.M.-B.), Service de Biostatistique, Lyon; and Université Lyon (D.M.-B.), Laboratoire de Biométrie et Biologie Évolutive, CNRS, UMR 5558, Pierre Benite, France.

Objective: To determine the time course of hazard for motor and nonmotor milestones of Parkinson disease (PD) in the long term and to investigate whether risk scales nonlinearly with time is instrumental in identifying changes in pathological processes and evaluating disease-modifying therapies in PD.

Methods: Outpatients with PD at the Lyon University Movement Disorders Center were evaluated for 7 clinical milestones in this retrospective cohort study, encompassing 4 domains of PD progression: (1) motor (motor fluctuations, dyskinesias); (2) axial (postural instability and falls, freezing of gait); (3) neuropsychiatric (impulse control disorders, hallucinations); and (4) cognitive (dementia) complications. For each complication, we estimated the outcome-specific hazard using parsimonious smooth parametric Poisson regression models allowing for nonlinear scaling over disease duration, age at diagnosis, current age, and their interaction. Read More

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December 2018
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encephalopathy: A distinctive generalized developmental and epileptic encephalopathy.

Neurology 2018 Dec 12. Epub 2018 Dec 12.

From the Epilepsy Research Centre (D.R.M.V., B.J.S., R.B., M.F.B., S.F.B., M.S.H., I.E.S.), Department of Medicine, University of Melbourne, Austin Health, Australia; Departments of Genetics (D.R.M.V., C.M.A.v.R.-A.) and Neurology (D.R.M.V.), University Medical Center Groningen, University of Groningen, the Netherlands; Pediatric Neurology Unit and Laboratories (D.M., M.M.) and Pediatric Neurology (R.G.), Neurogenetics and Neurobiology Unit and Laboratories, A. Meyer Children's Hospital, University of Florence, Italy; Department of Pediatrics and Pediatric Epilepsy Centre (H.X., W.X.W., Y.J.), Peking University First Hospital, Beijing, China; Department of Pediatrics (C.T.M., H.C.M.), Division of Genetic Medicine, University of Washington, Seattle; Population Health and Immunity Division (M.F.B.), Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; Department of Medical Biology (M.F.B.), University of Melbourne, Australia; Caulfield (D.W.), Melbourne, Australia; Department of Clinical Genetics (S.M.M.), Academic Medical Centre, Amsterdam, the Netherlands; Department of Clinical Genetics (A.S.B., G.M.S.M., I.M.B.H.v.d.L.), Erasmus University Medical Centre, Rotterdam, the Netherlands; Department of Clinical Genetics (J.M.v.H.), VU University Medical Center, Amsterdam, the Netherlands; Tasmanian Health Service (T.L.W.), Women's and Children's Services, Launceston General Hospital, Tasmania, Australia; TY Nelson Department of Neurology and Neurosurgery (R.I.W.) and Institute of Neuroscience and Muscle Research (R.I.W.), Children's Hospital at Westmead, Sydney, New South Wales, Australia; Department of Neurosciences (S.M.), Lady Cilento Children's Hospital, Brisbane, Australia; Department of Anatomical Pathology (R.M.K.), Austin Hospital, Melbourne, Australia; IRCCS Stella Maris Foundation (F.S., R.G.), Pisa, Italy; Klinikum Oldenburg (G.C.K.), Zentrum für Kinder-und Jugendmedizin, Klinik für Neuropädiatrie u.angeborene Stoffwechselerkrankungen, Germany; Centre of Epilepsy (Y.J.), Beijing Institute for Brain Disorders, China; Department of Paediatrics (I.E.S.), University of Melbourne, Royal Children's Hospital, Australia; and Florey Institute of Neurosciences and Mental Health (I.E.S.), Australia.

Objective: To delineate the epileptology, a key part of the phenotypic spectrum, in a large patient cohort.

Methods: Patients were recruited via investigators' practices or social media. We included patients with (likely) pathogenic variants or chromosome 6p21. Read More

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December 2018
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Evaluation of the Keeogo exoskeleton for assisting ambulatory activities in people with multiple sclerosis: an open-label, randomized, cross-over trial.

J Neuroeng Rehabil 2018 Dec 12;15(1):117. Epub 2018 Dec 12.

Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Charlestown, MA, USA.

Background: Although physical activity and exercise is known to benefit people with multiple sclerosis (MS), the ability of these individuals to participate in such interventions is difficult due to the mobility impairments caused by the disease. Keeogo is a lower-extremity powered exoskeleton that may be a potential solution for enabling people with MS to benefit from physical activity and exercise.

Methods: An open-label, randomized, cross-over trial was used to examine the immediate performance effects when using the device, and the potential benefits of using the device in a home setting for 2 weeks. Read More

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December 2018

Yoga to prevent mobility limitations in older adults: feasibility of a randomized controlled trial.

BMC Geriatr 2018 Dec 12;18(1):306. Epub 2018 Dec 12.

UCSD Stein Institute for Research on Aging, La Jolla, CA, USA.

Background: The loss of mobility during aging impacts independence and leads to further disability, morbidity, and reduced life expectancy. Our objective was to examine the feasibility and safety of conducting a randomized controlled trial of yoga for older adults at risk for mobility limitations.

Methods: Sedentary older adults (n = 46; age 60-89) were recruited and randomized to either yoga or a health education comparison group. Read More

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December 2018

Study on relationship between elderly sarcopenia and inflammatory cytokine IL-6, anti-inflammatory cytokine IL-10.

BMC Geriatr 2018 Dec 12;18(1):308. Epub 2018 Dec 12.

Department of Geratology Tianjin First Central Hospital, Tianjin, China.

Background And Objectives: The pathophysiological mechanism of sarcopenia in the elderly has not yet been fully understood. Here, we aim to explore the relationship between sarcopenia and the inflammatory cytokine interleukin-6 (IL-6), and the anti-inflammatory cytokine interleukin-10 (IL-10) in an elderly population.

Methods: Our study comprised 118 males and 46 females aged between 61 and 90 who had received a general medical examination in Tianjin First Central Hospital. Read More

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December 2018

Combined Hip Angle Variability and RPE Could Determine Gait Transition in Elite Race Walkers.

Motor Control 2018 Dec 12:1-14. Epub 2018 Dec 12.

1 Université Paris-Sud.

The aim of this study was to investigate the role of energy cost in locomotion, specifically the rate of perceived exertion and movement variability in gait transition for eight race walkers (RW) and seven nonrace walkers (NRW). We hypothesized that a group of correlated variables could serve as combined triggers. Participants performed a preferred transition speed (PTS) test, exhibiting a higher PTS for RW (10. Read More

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December 2018

A large knee osteochondral lesion treated using a combination of osteochondral autograft transfer and second-generation autologous chondrocyte implantation: A case report.

Regen Ther 2019 Jun 20;10:10-16. Epub 2018 Nov 20.

Department of Sports Medicine, Kameda Medical Center, Chiba, Japan.

Background: Full-thickness knee cartilage defects greater than 4 cm are best treated with autologous chondrocyte implantation (ACI). Since the articular cartilage surrounding the site of implantation does not always have the normal thickness desirable for successful engraftment, there may be benefit in combining ACI with osteochondral autograft transfer, which provides immediate restoration of condylar contour and mechanical function.

Case Presentation: A 19 year-old male who sustained a traumatic anterolateral femoral condyle osteochondral fracture underwent arthroscopic knee surgery three months after injury to harvest healthy cartilage to be sent to the Japan Tissue Engineering Co. Read More

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Gait Stability Training in a Virtual Environment Improves Gait and Dynamic Balance Capacity in Incomplete Spinal Cord Injury Patients.

Front Neurol 2018 20;9:963. Epub 2018 Nov 20.

Department of Research, Sint Maartenskliniek, Nijmegen, Netherlands.

Many patients with incomplete spinal cord injury (iSCI) have impaired gait and balance capacity, which may impact daily functioning. Reduced walking speed and impaired gait stability are considered important underlying factors for reduced daily functioning. With conventional therapy, patients are limited in training gait stability, but this can be trained on a treadmill in a virtual environment, such as with the Gait Real-time Analysis Interactive Lab (GRAIL). Read More

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November 2018

Quantifying Dynamic Balance in Young, Elderly and Parkinson's Individuals: A Systematic Review.

Front Aging Neurosci 2018 22;10:387. Epub 2018 Nov 22.

School of Human Kinetics, University of Ottawa, Ottawa, ON, Canada.

Falling is one of the primary concerns for people with Parkinson's Disease and occurs predominately during dynamic movements, such as walking. Several methods have been proposed to quantify dynamic balance and to assess fall risk. However, no consensus has been reached concerning which method is most appropriate for examining walking balance during unperturbed and perturbed conditions, particularly in Parkinson's Disease individuals. Read More

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November 2018

sPyNNaker: A Software Package for Running PyNN Simulations on SpiNNaker.

Front Neurosci 2018 20;12:816. Epub 2018 Nov 20.

Advanced Processor Technologies Group, School of Computer Science University of Manchester, Manchester, United Kingdom.

This work presents sPyNNaker 4.0.0, the latest version of the software package for simulating PyNN-defined spiking neural networks (SNNs) on the SpiNNaker neuromorphic platform. Read More

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November 2018

Real-time gait event detection in a real-world environment using a laser-ranging sensor and gyroscope fusion method.

Physiol Meas 2018 Oct 12. Epub 2018 Oct 12.

College of Biomedical Engineering and Instrument Science, Zhejiang University, Zhejiang Province ZheDa road 38#, Hangzhou, Zhejiang, 310027, CHINA.

Objective: Wearable gait event detection (GED) techniques have great potential for clinical applications by aiding the rehabilitation of individuals in their daily living environment. Unlike previous wearable GED techniques, which have been proposed for offline detection or laboratory settings, we aimed to develop a real-time GED system adapted for utilization in the daily living environment. Approach: This study presents a novel GED system in which foot clearance and sagittal angular velocity were incorporated to realize real-time GED in a real-world environment. Read More

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October 2018

Local Dynamic Stability of the Locomotion of Lower Extremity Joints and Trunk During Backward Upslope Walking.

J Mot Behav 2018 Dec 7:1-13. Epub 2018 Dec 7.

a Department of Orthopedic Surgery & Shanghai Key Laboratory of Orthopaedic Implant , Shanghai Ninth People's Hospital of Shanghai Jiao Tong University , Shanghai , China.

Backward slope walking was considered as a practical rehabilitation and training skill. However, its gait stability has been hardly studied, resulting in its limited application as a rehabilitation tool. In this study, the effect of walking direction and slope grade were investigated on the local dynamic stability of the motion of lower extremity joints and trunk segment during backward and forward upslope walking (BUW/FUW). Read More

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December 2018

Effects of a hybrid intervention combining exergaming and physical therapy among older adults in a long-term care facility.

Geriatr Gerontol Int 2018 Dec 6. Epub 2018 Dec 6.

Eastern Region Senior Citizen's Home, Ministry of Health and Welfare, Hualien, Taiwan.

Aim: Physical inactivity can cause physical frailty and sarcopenia. We investigated the effects of a hybrid intervention combining commercial exergaming with physical therapy, and clarified the reasons for physical inactivity among older adults.

Methods: This was a pilot study of older participants recruited from a long-term care facility assigned to either an experimental or a control group. Read More

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December 2018

Do individual differences in the distribution of activation between synergist muscles reflect individual strategies?

Exp Brain Res 2018 Dec 6. Epub 2018 Dec 6.

Faculty of Sport Sciences, Laboratory "Movement, Interactions, Performance" (EA 4334), University of Nantes, 25 bis boulevard Guy Mollet, 44300, Nantes, France.

Individual differences in the distribution of activation between synergist muscles have been reported during a wide variety of tasks. Whether these differences represent actual individual strategies is unknown. The aims of this study were to: (i) test the between-day reliability of the distribution of activation between synergist muscles, (ii) to determine the robustness of these strategies between tasks, and to (iii) describe the inter-individual variability of activation strategies in a large sample size. Read More

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December 2018

Intervertebral disc herniation in two coatis (Nasua nasua) and postoperative laminectomy membrane formation.

Tierarztl Prax Ausg K Kleintiere Heimtiere 2018 Oct 12;46(5):330-336. Epub 2018 Dec 12.

Magnetic resonance imaging revealed spinal cord compression due to intervertebral disc herniation of Hansen type I and II in the thoracolumbar vertebral column in two middle-aged coatis () with chronic progressive paraparesis. Surgical treatment included hemilaminectomy and partial corpectomy in one and dorsal laminectomy in the other coati. Both coatis recovered well after surgery. Read More

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October 2018
5 Reads

Lipomeningocele associated with diplomyelia in a dog.

Tierarztl Prax Ausg K Kleintiere Heimtiere 2018 Oct 12;46(5):323-329. Epub 2018 Dec 12.

A 2-year-old male neutered mixed breed dog with a body weight of 30 kg was presented for evaluation of a soft subcutaneous mass on the dorsal midline at the level of the caudal thoracic spine. A further clinical sign was intermittent pain on palpation of the area of the subcutaneous mass. The owner also described a prolonged phase of urination with repeated interruption and re-initiation of voiding. Read More

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October 2018
7 Reads

Measurements of Trunk Sway for Stance and Gait Tasks 2 Years after Vestibular Neurectomy.

Audiol Neurootol 2018 Dec 12;23(5):298-308. Epub 2018 Dec 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

The aim of this study was to investigate changes in balance control for stance and gait tasks in patients 2 years before and after vestibular neurectomy (VN) performed to alleviate intractable Meniere's disease. Amplitudes of trunk sway in roll and pitch directions were measured for stance and gait tasks in 19 patients using gyroscopes mounted at the lower-back. Measurements before VN and 2 years later were compared to those of healthy age-matched controls (HC). Read More

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December 2018

Overview of Metatarsalgia.

Orthopedics 2018 Dec 11:1-6. Epub 2018 Dec 11.

Metatarsalgia can be viewed as more of a symptom rather than a distinct diagnosis. Timing of forefoot pain during the gait cycle and evaluation of whether the pain is from anatomic abnormalities, indirect overloading, or iatrogenic causes can suggest a specific metatarsalgia etiology. A thorough physical examination of the lower extremity, especially evaluation of the plantar foot, and weight-bearing radiographs are critical for diagnosis and treatment. Read More

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December 2018
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Functional evaluation outcomes correlate with histomorphometric changes in the rat sciatic nerve crush injury model: A comparison between sciatic functional index and kinematic analysis.

PLoS One 2018 12;13(12):e0208985. Epub 2018 Dec 12.

Department of Motor Function Analysis, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Elucidating whether there is a correlation between biomechanical functions and histomorphometric data in the rat sciatic nerve crush injury model would contribute to an accurate evaluation of the regeneration state without sacrificing animals. The gold standard for functional evaluation is the sciatic functional index (SFI) despite there being intrinsic shortcomings. Kinematic analysis is considered a reliable and sensitive approach for functional evaluation, most commonly assessed as ankle angle at various phases of a gait cycle. Read More

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December 2018
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Comparison of ground reaction force measurements in a population of Domestic Shorthair and Maine Coon cats.

PLoS One 2018 12;13(12):e0208085. Epub 2018 Dec 12.

Department for Companion Animals and Horses, University Clinic for Small Animals, Small Animal Surgery, Section for Physical Therapy, University of Veterinary Medicine, Veterinärplatz, Vienna, Austria.

Current research on gait analysis mostly involves horses and dogs. Feline kinetics and kinematics are being investigated and receiving more clinical interest at present. Ground reaction forces measured on pressure-sensitive mattresses have been established in healthy Domestic Shorthair cats (DSH). Read More

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December 2018
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Comparative biomechanical evaluation of two technologically different microprocessor-controlled prosthetic knee joints in safety-relevant daily-life situations.

Biomed Tech (Berl) 2018 Dec 12. Epub 2018 Dec 12.

Ottobock SE & Co. KGaA, Clinical Research and Services, Research Biomechanics, 37075 Göttingen, Germany.

Safety-relevant gait situations (walking on stairs and slopes, walking backwards, walking with small steps, simulated perturbations of swing phase extension) were investigated in a motion analysis laboratory with six unilateral transfemoral amputees using two different microprocessor-controlled prosthetic knee joints (Rheo Knee XC, C-Leg). A randomized crossover design was chosen. The study results imply that the performance and safety potential of a microprocessor-controlled knee joint can be associated with the individual control algorithms and the technological concepts that are implemented to generate motion resistances for controlling flexion and extension movements. Read More

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December 2018

Physiotherapy practice patterns in gait rehabilitation for adults with acquired brain injury.

Brain Inj 2018 Dec 12:1-16. Epub 2018 Dec 12.

a Department of Physical Therapy , University of Toronto , Toronto , Canada.

Objective: Gait dysfunction is common following acquired brain injury (ABI). Clinical practice guidelines can improve patient outcomes; however, information regarding ABI-specific management of gait dysfunction is limited. This study aimed to describe practice patterns of Canadian physiotherapists regarding gait rehabilitation in adults post-ABI. Read More

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December 2018
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Parkinson's disease: a short story of 200 years.

Histol Histopathol 2018 Dec 12:18073. Epub 2018 Dec 12.

Clinical and Experimental Neuroscience Group (NiCE-IMIB), Department of Human Anatomy and Psychobiology, Institute for Aging Research, School of Medicine, University of Murcia, Murcia, Spain.

After Alzheimer's disease, Parkinson's disease (PD) is the second most prevalent and incidental neurodegenerative disorder, affecting more than 2% of the population older than 65 years old. Since it was first described 200 years ago by Dr James Parkinson, great steps have been made in the understanding of the pathology. However, the cause(s) that initiates and perpetuates the neurodegenerative process is (are) still not clear. Read More

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December 2018
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Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila.

Dev Biol 2019 Jan 25;445(1):37-53. Epub 2018 Oct 25.

Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, Irvine, CA 92697-2300, USA. Electronic address:

Analysis of mutants that affect formation and function of the Drosophila larval neuromuscular junction (NMJ) has provided valuable insight into genes required for neuronal branching and synaptic growth. We report that NMJ development in Drosophila requires both the Drosophila ortholog of FNDC3 genes; CG42389 (herein referred to as miles to go; mtgo), and CCT3, which encodes a chaperonin complex subunit. Loss of mtgo function causes late pupal lethality with most animals unable to escape the pupal case, while rare escapers exhibit an ataxic gait and reduced lifespan. Read More

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January 2019

Visual-Somatosensory Integration and Quantitative Gait Performance in Aging.

Front Aging Neurosci 2018 27;10:377. Epub 2018 Nov 27.

Division of Cognitive and Motor Aging, Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, United States.

The ability to integrate information across sensory modalities is an integral aspect of mobility. Yet, the association between visual-somatosensory (VS) integration and gait performance has not been well-established in aging. A total of 333 healthy older adults (mean age 76. Read More

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November 2018

The immediate influence of implicit motor learning strategies on spatiotemporal gait parameters in stroke patients: a randomized within-subjects design.

Clin Rehabil 2018 Dec 12:269215518816359. Epub 2018 Dec 12.

1 Research Centre for Nutrition, Lifestyle and Exercise, Faculty of Health, Zuyd University of Applied Sciences, Heerlen, The Netherlands.

Objectives:: To investigate immediate changes in walking performance associated with three implicit motor learning strategies and to explore patient experiences of each strategy.

Design:: Participants were randomly allocated to one of three implicit motor learning strategies. Within-group comparisons of spatiotemporal parameters at baseline and post strategy were performed. Read More

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December 2018