56,763 results match your criteria Gait & Posture [Journal]


Optimal Muscle Selection for OnabotulinumtoxinA Injections in Poststroke Lower-Limb Spasticity: A Randomized Trial.

Am J Phys Med Rehabil 2019 May;98(5):360-368

From the MossRehab Gait and Motion Analysis Laboratory, Elkins Park, Pennsylvania (AE); McGill University, Division of Neurology, Montreal General Hospital, Montreal, Quebec, Canada (THW); Staffordshire University, Faculty of Health and North Staffordshire Rehabilitation Centre, Haywood Hospital, Stoke-on-Trent, United Kingdom (ABW); Halifax Health, Brooks Rehabilitation, Daytona Beach, Florida (CG); Allergan plc, Bridgewater, New Jersey (CL); and Allergan plc, Irvine, California (RD).

Objective: The aim of the study was to identify optimal muscle selection patterns for onabotulinumtoxinA treatment of poststroke lower-limb spasticity.

Design: Adults with poststroke lower-limb spasticity (ankle Modified Ashworth Scale ≥3) were randomized to onabotulinumtoxinA (300 U, mandatory ankle plantar flexors; ≤100 U, optional lower-limb muscles) or placebo. Post hoc analysis assessed the impact of muscle selection patterns on ankle Modified Ashworth Scale and physician-assessed Clinical Global Impression of Change based on change from baseline to average of weeks 4/6 versus placebo. Read More

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http://dx.doi.org/10.1097/PHM.0000000000001101DOI Listing
May 2019
1 Read

Comparison of glenohumeral and humerothoracical range of motion in healthy controls, osteoarthritic patients and patients after total shoulder arthroplasty performing different activities of daily living.

Gait Posture 2019 Apr 6;71:20-25. Epub 2019 Apr 6.

Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany. Electronic address:

Purpose: The purpose of this study was to examine how total shoulder arthroplasty improves performance of activities of daily living compared to patients with glenohumeral osteoarthritis and how they perform compared to healthy controls.

Methods: Glenohumeral and humerothoracical elevation used by patients with primary osteoarthritis (12 participants, 16 shoulders), after total shoulder arthroplasty (16 participants, 24 shoulders) and healthy controls (11 participants, 22 shoulders) for four different activities of daily living were assessed using 3D motion analysis. Analysis of range of motion and angle time series was performed. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.04.001DOI Listing

Symmetrical cruciate-retaining versus medial pivot prostheses: The effect of intercondylar sagittal conformity on knee kinematics and contact mechanics.

Comput Biol Med 2019 Mar 10;108:101-110. Epub 2019 Mar 10.

Department of Mechanical Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.

Background: A total knee arthroplasty should restore the mechanical function of the knee and enable patients to perform desired daily activities. The joint kinematics and contact mechanics performance are important determinants of the success of total knee arthroplasty devices. The purpose of this study was to determine the effect of intercondylar sagittal conformity on kinematics and contact mechanics. Read More

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http://dx.doi.org/10.1016/j.compbiomed.2019.03.005DOI Listing

Association between sarcopenia and diabetes in community dwelling elderly in the Amazon region - Viver Mais Project.

Arch Gerontol Geriatr 2019 Mar 27;83:121-125. Epub 2019 Mar 27.

State University Of Pará, Brazil; Hospital Cynthia Charone, Brazil.

Background: Studies indicate the intrinsic relationship between sarcopenia and diabetes mellitus (DM) pathophysiological mechanisms. Changes in insulin and muscular metabolism are features of diabetic patients and can interact as sarcopenic accelerators. Conversely, sarcopenic patients feature lower glucose tolerance and higher serum insulin levels, predisposing them to DM. Read More

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http://dx.doi.org/10.1016/j.archger.2019.03.020DOI Listing

An Objective Assessment of the Effect of Anesthetizing the Median Nerve on Lameness Caused by Pain in the Cubital Joint.

J Equine Vet Sci 2019 Apr 19;75:9-13. Epub 2018 Dec 19.

Department of Clinical Sciences, Auburn University College of Veterinary Medicine, Auburn, AL.

The median nerve, along with the ulnar nerve, is often anesthetized when performing a lameness examination in horses. Because of the close proximity of the median nerve to the cubital joint, proximal migration of local anesthetic might ameliorate pain originating from the cubital joint. The objective of this study was to determine if a median nerve block will ameliorate lameness caused by pain in the cubital joint. Read More

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http://dx.doi.org/10.1016/j.jevs.2018.12.008DOI Listing

Orthopedic Manifestations of Bruck Syndrome: A Case Series with Intermediate to Long-term Follow-Up.

Case Rep Orthop 2019 13;2019:8014038. Epub 2019 Mar 13.

Department of Orthopedic Surgery, Alfred I. duPont Hospital for Children, Wilmington, DE, USA.

The aim of this study was to evaluate the association of contractures, fractures, and deformities in four patients with Bruck syndrome treated in our facility. Data were collected from medical records, radiographs, dual-energy X-ray absorptiometry (DEXA) scans, genetic tests, and gait analysis. All had contractures at birth and genotypic findings including mutations in PLOD2 or FPKB10. Read More

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http://dx.doi.org/10.1155/2019/8014038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436336PMC

Neuromusculoskeletal Simulation Reveals Abnormal Rectus Femoris-Gluteus Medius Coupling in Post-stroke Gait.

Front Neurol 2019 2;10:301. Epub 2019 Apr 2.

Walker Department of Mechanical Engineering, University of Texas at Austin, Austin, TX, United States.

Post-stroke gait is often accompanied by muscle impairments that result in adaptations such as hip circumduction to compensate for lack of knee flexion. Our previous work robotically enhanced knee flexion in individuals post-stroke with Stiff-Knee Gait (SKG), however, this resulted in greater circumduction, suggesting the existence of abnormal coordination in SKG. The purpose of this work is to investigate two possible mechanisms of the abnormal coordination: (1) a reflex coupling between stretched quadriceps and abductors, and (2) a coupling between volitionally activated knee flexors and abductors. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2019.00301
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http://dx.doi.org/10.3389/fneur.2019.00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454148PMC
April 2019
1 Read

Cerebellar Liponeurocytoma: A Rare Fatty Tumor and its Literature Review.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):360-363

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Cerebellar liponeurocytoma is a rare oncological entity, and the knowledge about the treatment and outcome of these rare tumors is still evolving. Very few cases have been described in literature. We report a middle-aged male who presented with raised intracranial pressure features and gait ataxia. Read More

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http://www.ruralneuropractice.com/text.asp?2019/10/2/360/254
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http://dx.doi.org/10.4103/jnrp.jnrp_266_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454964PMC
April 2019
1 Read

Clinical Characteristics of Essential Tremor in South India: A Hospital-Based Cohort Study.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):245-249

Department of Neurology, Princess Esra Hospital, Deccan College of Medical Science, Hyderabad, Telangana, India.

Introduction: Essential tremor (ET) is the most common adult movement disorder. Classic ET is characterized by action tremor of hands (95% cases), and tremor involving other regions is less common. Recent studies have revealed a few patients exhibiting nontremor features that include cognitive disorders, tandem gait abnormality, mood fluctuations, olfactory abnormality, hearing impairment, and sleep disorders. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_348_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454942PMC

Gait and trunk kinematics during prolonged turning in Parkinson's disease with freezing of gait.

Parkinsonism Relat Disord 2019 Apr 13. Epub 2019 Apr 13.

Department of Kinesiology and Physical Education, McGill University, Montreal, Quebec, Canada; Centre for Interdisciplinary Research in Rehabilitation, Montreal, Quebec, Canada. Electronic address:

Introduction: Although turning during walking is known to trigger freezing of gait (FOG) in Parkinson's disease (PD), little is known about kinematic strategies used by individuals with PD and FOG while performing prolonged turning.

Objective: Our aim was to compare gait and trunk kinematics during straight walking and continuous turning over 20-min in PD with and without FOG.

Methods: 18 individuals with idiopathic PD (n = 9 with FOG, n = 9 without FOG), performed two 20-min walking tasks: straight ahead, and turning, in a laboratory setting in their OFF medication state. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2019.04.011DOI Listing

The influence of isokinetic peak torque and muscular power on the functional performance of active and inactive community-dwelling elderly: a cross-sectional study.

Braz J Phys Ther 2019 Apr 5. Epub 2019 Apr 5.

Postgraduate Program in Rehabilitation Sciences, Universidade de Brasília (UnB) - Campus Ceilândia, Brasília, DF, Brazil. Electronic address:

Objective: To verify the importance of the isokinetic muscular torque and power of knee extensors and flexors on the functional performance of active and inactive elderly women.

Methods: A cross-sectional observational study was conducted with 116 community-dwelling women (≥60 years old) without severe cognitive and/or motor dysfunction. Isokinetic muscle function was measured by peak torque and muscle power at 60°/s (5 repetitions) and 180°/s (15 repetitions), respectively. Read More

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http://dx.doi.org/10.1016/j.bjpt.2019.03.003DOI Listing

A Dynamic Bayesian Network model for the simulation of Amyotrophic Lateral Sclerosis progression.

BMC Bioinformatics 2019 Apr 18;20(Suppl 4):118. Epub 2019 Apr 18.

Department of Information Engineering, University of Padova, Gradenigo 6/b, 35131, Padova, Italy.

Background: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease progressively affecting upper and lower motor neurons in the brain and spinal cord. Mean life expectancy is three to five years, with paralysis of muscles, respiratory failure and loss of vital functions being the common causes of death. Clinical manifestations of ALS are heterogeneous due to the mix of anatomic regions involvement and the variability in disease course; consequently, diagnosis and prognosis at the level of individual patient is really challenging. Read More

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http://dx.doi.org/10.1186/s12859-019-2692-xDOI Listing

Gluteus medius activity during gait is altered in individuals with chronic ankle instability: An ultrasound imaging study.

Gait Posture 2019 Apr 11;71:7-13. Epub 2019 Apr 11.

University of Virginia Exercise and Sports Injury Lab, 210 Emmet Street South, Charlottesville, VA, 22904-4407, United States. Electronic address:

Background: Altered gait mechanics are frequently reported in individuals with chronic ankle instability (CAI), and increasing information suggests proximal muscle adaptations occur in this population. Ultrasound imaging (USI) offers a visual means to evaluate muscle activity during movement, and overcomes limitations of electromyography (EMG) to detect hip muscle activity.

Research Question: A descriptive laboratory study was conducted to determine if gluteus maximus (GMAX) and medius (GMED) muscle activity differed throughout gait in patients with CAI compared to healthy counterparts. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183171
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http://dx.doi.org/10.1016/j.gaitpost.2019.04.007DOI Listing
April 2019
7 Reads

Performance of stair negotiation in patients with cerebral palsy and stiff knee gait.

Gait Posture 2019 Apr 9;71:14-19. Epub 2019 Apr 9.

Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany; Pediatric Orthopaedics and Traumatology, University, Children's Hospital Zurich - Eleonore Foundation, Steinwiesstrasse 75, 8032 Zurich, Switzerland. Electronic address:

Background: Due to the limited knee range of motion, achieving adequate foot clearance while walking on level ground constitutes a major problem for patients with cerebral palsy and stiff knee gait. Stair negotiation as an activity of daily life requires a considerably higher knee range of motion than level ground walking, but little is known yet as to whether such patients are able to walk stairs.

Research Question: The aim of this study was to investigate how patients with a limited knee range of motion negotiate stairs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183178
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http://dx.doi.org/10.1016/j.gaitpost.2019.04.005DOI Listing
April 2019
2 Reads

Selective effect of static stretching, concentric contractions, and a one-leg balance task on ankle motion sense in young and older adults.

Gait Posture 2019 Apr 10;71:1-6. Epub 2019 Apr 10.

Faculty of Sport, University of Ljubljana, Ljubljana, Slovenia.

Background: Being aware of ankle movement and motor control has a critical role in maintaining balance during functional activities such as standing, walking, and running. Since the somatosensory system declines with aging, this is even more important for older adults.

Research Question: How do different exercise modalities (static stretching, one-leg balance task, concentric contractions, and control) acutely influence ankle motion sense in young and older adults?

Methods: Seventeen young and fifteen older participants performed four different intervention protocols (static stretching, one-leg balance task, concentric contractions, and control) in random order. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.04.006DOI Listing

To stitch or not to stitch: A case review: Auricular lacerations involving cartilage management in the emergency department.

Australas Emerg Care 2018 May 6;21(2):75-79. Epub 2018 Jun 6.

Emergency and Trauma Centre, The Alfred Hospital, Commercial Road, Prahran, Victoria 3004, Australia.

Patients with Parkinsonism are at risk of frequent falls by virtue of their unstable gait. Auricular lacerations involving the cartilage are usually managed by Plastics Surgeons. Patient Mr Jones (an alias for this case review) had sustained a significant full thickness auricular laceration that was complicated by a past medical history with Parkinson's disease. Read More

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http://dx.doi.org/10.1016/j.auec.2018.03.002DOI Listing

Role of physical performance measures for identifying functional disability among Chinese older adults: Data from the China Health and Retirement Longitudinal Study.

PLoS One 2019 18;14(4):e0215693. Epub 2019 Apr 18.

West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.

Background: Functional disability is a common health burden in older adults and follows a hierarchical pattern. Physical performance measures are useful for the objective estimation of functional disability. This study primarily aimed to compare the validity of handgrip strength and gait speed, alone and in combination, for recognizing the functional disability among Chinese older adults. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215693PLOS
April 2019
1 Read

Backward walking observational training improves gait ability in patients with chronic stroke: randomised controlled pilot study.

Int J Rehabil Res 2019 Apr 15. Epub 2019 Apr 15.

Department of Physical Therapy, Graduate School of Gachon University.

Backward walking has a positive effect on gait ability. Action observational training is an effective treatment method for stroke neurological disorders. This randomised comparator-controlled pilot study aimed to evaluate the feasibility of backward walking observational training on the gait ability of chronic stroke patients. Read More

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http://dx.doi.org/10.1097/MRR.0000000000000352DOI Listing

Usability of a daily mHealth application designed to address mobility, speech and dexterity in Parkinson's disease.

Neurodegener Dis Manag 2019 Apr 18. Epub 2019 Apr 18.

Program in Physical Therapy, Washington University School of Medicine, St Louis, MO, USA.

This study investigated the usability of a mobile health (mHealth) smartphone application to treat gait, speech and dexterity in people with Parkinson's disease. Participants either used an mHealth application (intervention) or maintained their normal routine (control) for 12 weeks and were evaluated at baseline and post-test time points for primary outcome measures of adherence, gait, speech and dexterity. mHealth application adherence was compared with percent change scores on gait, speech and dexterity measures. Read More

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http://dx.doi.org/10.2217/nmt-2018-0036DOI Listing

Longitudinal Changes in Muscle Mass and Function in Older Men at Increased Risk for Sarcopenia - The FrOST-Study.

J Frailty Aging 2019 ;8(2):57-61

Professor Dr. Wolfgang Kemmler, Institute of Medical Physics, Friedrich-Alexander University Erlangen-Nürnberg, Henkestrasse 91 91052 Erlangen, Germany, Tel: 0049 9131-8523999, Fax: 0049 9131-8522824, Email:

Background: Declines in muscle mass and function are inevitable developments of the advanced aging process. Corresponding dimensions of longitudinal changes in at-risk populations are still scarce although clinically relevant. The present study monitored changes in morphologic and functional sarcopenia criteria related to sarcopenia in older men with low muscle mass over a period of 24 months. Read More

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http://dx.doi.org/10.14283/jfa.2019.9DOI Listing
January 2019

[Recognition and classification of posture and gait patterns of rollator users by distance measurements-a comparison between clinical assessment and automatic classification].

Z Gerontol Geriatr 2019 Apr 17. Epub 2019 Apr 17.

Budelmann Elektronik GmbH, Münster, Deutschland.

Background: This article describes the development of an add-on module for wheeled walkers dedicated to sensor-based posture and gait pattern recognition with the goal to develop an everyday aid for fall prevention. The core contribution is a clinical study that compared single gait parameter assessments coming from medical staff to those obtained from an automatic classification algorithm, i. e. Read More

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http://dx.doi.org/10.1007/s00391-019-01544-0DOI Listing

USE OF 2-DIMENSIONAL SAGITTAL KINEMATIC VARIABLES TO ESTIMATE GROUND REACTION FORCE DURING RUNNING.

Int J Sports Phys Ther 2019 Apr;14(2):174-179

Rueckert-Hartman College of Health Professions, School of Physical Therapy, Regis University, Denver, CO.

Background: Variations in vertical loading rates have been associated with overuse injuries of the lower extremity; however, they are typically collected using 3-dimensional motion capture systems and in-ground force plates not available to most clinicians because of cost and space constraints.

Purpose: The purpose of this study was to determine if kinetic measures commonly used to describe lower extremity loading characteristics could be estimated from step rate and specific sagittal plane kinematic variables captured using 2-dimensional motion analysis during treadmill running.

Study Design: Observational Study. Read More

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Influence of tibiofemoral congruency design on the wear of patient-specific unicompartmental knee arthroplasty using finite element analysis.

Bone Joint Res 2019 Mar 2;8(3):156-164. Epub 2019 Apr 2.

Department of Mechanical Engineering, Department of Mechanical Engineering, Yonsei University, Seoul, South Korea.

Objectives: Unicompartmental knee arthroplasty (UKA) is an alternative to total knee arthroplasty for patients who require treatment of single-compartment osteoarthritis, especially for young patients. To satisfy this requirement, new patient-specific prosthetic designs have been introduced. The patient-specific UKA is designed on the basis of data from preoperative medical images. Read More

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http://dx.doi.org/10.1302/2046-3758.83.BJR-2018-0193.R1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444019PMC

Effect of tibial component alignment on knee kinematics and ligament tension in medial unicompartmental knee arthroplasty.

Bone Joint Res 2019 Mar 2;8(3):126-135. Epub 2019 Apr 2.

Department of Orthopedic Surgery, Kyoto University, Graduate School of Medicine, Kyoto, Japan.

Objectives: Unicompartmental knee arthroplasty (UKA) is one surgical option for treating symptomatic medial osteoarthritis. Clinical studies have shown the functional benefits of UKA; however, the optimal alignment of the tibial component is still debated. The purpose of this study was to evaluate the effects of tibial coronal and sagittal plane alignment in UKA on knee kinematics and cruciate ligament tension, using a musculoskeletal computer simulation. Read More

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http://dx.doi.org/10.1302/2046-3758.83.BJR-2018-0208.R2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444020PMC

Comparison of gait with and without ankle-foot orthoses after lower limb surgery in children with unilateral cerebral palsy.

J Child Orthop 2019 Apr;13(2):180-189

Medical Faculty, Department of Interdisciplinary Health Science, University of Oslo, Oslo, Norway.

Purpose: Children with spastic unilateral cerebral palsy (SUCP) frequently undergo lower limb surgery to improve gait. Postoperatively, ankle-foot orthoses (AFOs) are used to maintain the surgical corrections and provide adequate mechanical support. Our aim was to evaluate changes in gait and impacts of AFOs one-year postoperatively. Read More

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http://dx.doi.org/10.1302/1863-2548.13.180146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442508PMC

Serial ankle casts for patients with idiopathic toe walking: effects on functional gait parameters.

J Child Orthop 2019 Apr;13(2):147-154

University Center for Orthopaedics and Trauma Surgery, Carl Gustav Carus University Hospital, Technical University of Dresden, Dresden, Germany.

Purpose: The aim of the present study was to investigate the functional effects on gait parameters of serial ankle casts for patients with idiopathic toe walking (ITW), in comparison with an unremarkable control group.

Methods: A prospective trial with a pre-test-post-test control group design included ten patients with ITW and ten healthy matched children. Children with ITW underwent serial casting to stretch the plantar flexors, with two 14-day periods with walking plaster casts set at the maximum available ankle dorsiflexion. Read More

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http://dx.doi.org/10.1302/1863-2548.13.180183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442509PMC

[Early functional recovery of direct anterior approach versus anterolateral approach for total hip arthroplasty].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):268-272

Department of Orthopaedics, Guizhou Provincial people's Hospital, Guiyang 550002, China.

Objective: To evaluate the early clinical effects of direct anterior approach (DAA) versus anterolateral approach (ALA) on safety and functional recovery following total hip arthroplasty (THA).

Methods: Between January 2015 and May 2016, a randomized clinical trial was performed at Guizhou Provincial People's Hospital. A total of 50 patients who underwent THA were allocated for either the DAA (n=25) or ALA (n=25). Read More

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Isolated pontine involvement in posterior reversible encephalopathy syndrome with coincidental acute ischaemic stroke.

BMJ Case Rep 2019 Apr 16;12(4). Epub 2019 Apr 16.

DMOP, Basildon University Hospital, Basildon, Essex, UK.

Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological syndrome characterised by a unique reversible pattern on imaging and total regression of clinical symptoms and signs. We describe an unusual case of PRES with isolated pontine involvement with coincidental acute ischaemic stroke in a 60-year-old man who presented with headache, unsteadiness of gait, blurred vision and elevated blood pressure. MRI scan revealed an expanded pons with diffuse T2 and Fluid attenuated Inversion Recovery (FLAIR) hyperintensities and an acute infarct in the right temporal lobe. Read More

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http://dx.doi.org/10.1136/bcr-2018-227132DOI Listing
April 2019
1 Read

Hidden Markov Model-Based Smart Annotation for Benchmark Cyclic Activity Recognition Database Using Wearables.

Sensors (Basel) 2019 Apr 16;19(8). Epub 2019 Apr 16.

Machine Learning and Data Analytics Lab, Computer Science Department, 91052 Erlangen, Germany.

Activity monitoring using wearables is becoming ubiquitous, although accurate cycle level analysis, such as step-counting and gait analysis, are limited by a lack of realistic and labeled datasets. The effort required to obtain and annotate such datasets is massive, therefore we propose a smart annotation pipeline which reduces the number of events needing manual adjustment to 14%. For scenarios dominated by walking, this annotation effort is as low as 8%. Read More

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http://dx.doi.org/10.3390/s19081820DOI Listing

Multicomponent exercise and the hallmarks of frailty: Considerations on cognitive impairment and acute hospitalization.

Exp Gerontol 2019 Apr 14. Epub 2019 Apr 14.

Department of Health Sciences, Navarrabiomed, IdiSNA, CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Public University of Navarra, Pamplona, Navarra, Spain. Electronic address:

Frailty syndrome encompasses several physical hallmarks such as loss of muscle strength, power output and mass, which leads to poor gait ability, fatigue, falls and overall difficulty to perform activities of daily living. On the other hand, physical exercise interventions induce marked improvements in frailty physical hallmarks (e.g. Read More

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http://dx.doi.org/10.1016/j.exger.2019.04.007DOI Listing

The long-term effects of an implantable drop foot stimulator on gait in hemiparetic patients.

PLoS One 2019 17;14(4):e0214991. Epub 2019 Apr 17.

Christian Doppler Laboratory for Restoration of Extremity Function, Medical University of Vienna, Vienna, Austria.

Drop foot is a frequent abnormality in gait after central nervous system lesions. Different treatment strategies are available to functionally restore dorsal extension during swing phase in gait. Orthoses as well as surface and implantable devices for electrical stimulation of the peroneal nerve may be used in patients who do not regain good dorsal extension. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214991PLOS
April 2019
7 Reads

Prevalence of sarcopenia and its associated factors: the impact of muscle mass, gait speed, and handgrip strength reference values on reported frequencies.

Clinics (Sao Paulo) 2019 04 8;74:e477. Epub 2019 Apr 8.

Laboratorio de Envelhecimento Humano - GeronLab, Faculdade de Ciencias Medicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, BR.

Objectives: Sarcopenia is a common treatable geriatric condition. The aim of this study was to estimate the prevalence of sarcopenia and its associated factors in community-dwelling elderly living in Rio de Janeiro, Brazil, and to discuss the impact of different muscle mass, handgrip strength and gait speed cut-off values on the reported frequency of sarcopenia.

Methods: The health habits, functional capacity, and anthropometric measurements of 745 individuals aged ≥65 years from the Frailty in Brazilian Older People study were analyzed. Read More

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http://dx.doi.org/10.6061/clinics/2019/e477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445156PMC

7.0T ultrahigh-field MRI directly visualized the pedunculopontine nucleus in Parkinson's disease patients.

Clinics (Sao Paulo) 2019 15;74:e573. Epub 2019 Apr 15.

Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Xicheng District, Beijing, 100053, P.R., China.

Objectives: The pedunculopontine nucleus (PPN) is considered a promising new target for neurostimulation in Parkinson's disease (PD) patients with postural instability and gait disturbance that is refractory to other treatment modalities. However, the PPN is typically difficult to visualize with magnetic resonance imaging (MRI) at clinical field strengths, which greatly limits the PPN as a viable surgical target for deep brain stimulation (DBS). Thus, the aim of this study is to directly visualize the PPN based on 7. Read More

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http://dx.doi.org/10.6061/clinics/2019/e573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456917PMC
April 2019
1 Read

The Responsiveness of Triaxial Accelerometer Measurement of Gait Ataxia Is Higher than That of the Scale for the Assessment and Rating of Ataxia in the Early Stages of Spinocerebellar Degeneration.

Cerebellum 2019 Apr 16. Epub 2019 Apr 16.

Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N15W7, Kita-ku, Sapporo, 060-8638, Japan.

We reported previously that the average medial-lateral gait amplitude while walking on a straight path determined using triaxial accelerometers fixed on the middle of the upper back may be a quantitative and concise indicator for the severity of cerebellar ataxia. Considering that gait ataxia is a typical initial symptom in a variety of spinocerebellar degeneration (SCD), we aimed to develop quantitative biomarkers for cerebellar ataxia as metric variables. We used triaxial accelerometers to analyze gait parameters in 14 patients with SCD at 3 points over 3 years (at baseline, 1. Read More

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http://link.springer.com/10.1007/s12311-019-01025-5
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http://dx.doi.org/10.1007/s12311-019-01025-5DOI Listing
April 2019
1 Read

The assessment of instability in the osteoarthritic knee.

EFORT Open Rev 2019 Mar 8;4(3):70-76. Epub 2019 Mar 8.

Department of Biomedical Engineering, University of Strathclyde, Glasgow, UK.

Patient-reported instability is a common complaint amongst those with knee arthritis.Much research has examined the assessment of self-reported instability in the knee; however, no definitive quantitative measure of instability has been developed.This review focuses on the current literature investigating the nature of self-reported instability in the arthritic knee and discusses the possibilities of further investigation. Read More

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https://online.boneandjoint.org.uk/doi/10.1302/2058-5241.4.1
Publisher Site
http://dx.doi.org/10.1302/2058-5241.4.170079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440299PMC
March 2019
1 Read

Involvement of cortical dysfunction in frequent falls in patients with Parkinson's disease.

Parkinsonism Relat Disord 2019 Apr 11. Epub 2019 Apr 11.

Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan. Electronic address:

Introduction: Gait and balance disorders are common clinical features of Parkinson's disease (PD). Although falls significantly affect the activities of daily living (ADL) and quality of life (QOL) of patients with PD, the underlying neural mechanisms associated with frequent falls in PD patients are still unclear.

Methods: Hypothesizing that the cerebral cortex would contribute to frequent falls in PD, we obtained 3D T1-weighted images from 91 non-dementia patients with PD and performed voxel-based morphometric analysis (VBM). Read More

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http://dx.doi.org/10.1016/j.parkreldis.2019.04.007DOI Listing

Free-view gait recognition.

PLoS One 2019 16;14(4):e0214389. Epub 2019 Apr 16.

National Engineering Laboratory for Video Technology, School of Electronics Engineering and Computer Sciences, Peking University, Haidian, China.

Human gait has been shown to be an effective biometric measure for person identification at a distance. On the other hand, changes in the view angle pose a major challenge for gait recognition as human gait silhouettes are usually different from different view angles. Traditionally, such a multi-view gait recognition problem can be tackled by View Transformation Model (VTM) which transforms gait features from multiple gallery views to the probe view so as to evaluate the gait similarity. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214389PLOS
April 2019
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Prediction of Freezing of Gait in Parkinson's Disease using Statistical Inference and Lower-Limb Acceleration Data.

IEEE Trans Neural Syst Rehabil Eng 2019 Apr 11. Epub 2019 Apr 11.

Freezing of gait (FoG) is a common type of motor dysfunction in advanced Parkinson's disease (PD) associated with falls. Over the last decade, a significant amount of studies has been focused on detecting FoG episodes in clinical and home environments. Yet, there remains a paucity of techniques regarding real-time prediction of FoG before its occurrence. Read More

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http://dx.doi.org/10.1109/TNSRE.2019.2910165DOI Listing

Factors associated with impairment in gait speed in older people with clinically normal gait. A cross-sectional study.

Aging Clin Exp Res 2019 Apr 12. Epub 2019 Apr 12.

Fundación de Investigación Biomédica del Hospital Universitario de Getafe, Getafe, Spain.

Background: Health professionals commonly use gait speed in the evaluation of functional status in older people. However, only a limited number of studies have assessed gait speed in the absence of disorders of gait, using confounding factors and exclusion criteria coming from studies conducted in younger people. Our study aims to analyse which factors are associated with gait speed in older people with normal clinical gait. Read More

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http://link.springer.com/10.1007/s40520-019-01187-6
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http://dx.doi.org/10.1007/s40520-019-01187-6DOI Listing
April 2019
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Author Correction: Variability of crossing phase in older people with Parkinson's disease is dependent of obstacle height.

Sci Rep 2019 Apr 16;9(1):6344. Epub 2019 Apr 16.

São Paulo State University (Unesp) - Campus Rio Claro, Posture and Gait Studies Laboratory (LEPLO), Department of Physical Education, Rio Claro, Brazil.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. Read More

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http://dx.doi.org/10.1038/s41598-019-40318-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465558PMC

Walk, Talk and Listen: a pilot randomised controlled trial targeting functional fitness and loneliness in older adults with hearing loss.

BMJ Open 2019 Apr 14;9(4):e026169. Epub 2019 Apr 14.

Medicine, University of British Columbia, Kelowna, British Columbia, Canada.

Background: Age-related hearing loss (HL) is a prevalent disability associated with loneliness, isolation, declines in cognitive and physical function and premature mortality. Group audiological rehabilitation (GAR) and hearing technologies address communication and cognitive decline. However, the relationship between loneliness, physical function and GAR among older adults with HL has not been studied. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026169DOI Listing

When motor control gets out of hand: Speeding up triggers freezing in the upper limb in Parkinson's disease.

Parkinsonism Relat Disord 2019 Apr 8. Epub 2019 Apr 8.

Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Belgium. Electronic address:

Introduction: Patients with Parkinson's disease (PD) can suffer from sudden movement arrests during upper limb tasks. The current study investigated a test to assess freezing of the upper limbs (FOUL) at two speed conditions to improve the sensitivity of FOUL detection.

Methods: Forty-nine patients with PD and 10 age-matched controls (HC) performed a freezing-provoking writing task, requiring up- and down-stroke writing at varying sizes in-between visual target zones indicating funnel-shapes on a touch-sensitive tablet. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2019.04.005DOI Listing
April 2019
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A biomechanical study of gait initiation in Down syndrome.

BMC Neurol 2019 Apr 15;19(1):66. Epub 2019 Apr 15.

Department of Electronics, Information and Bioengineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133, Milan, Italy.

Background: Gait Initiation (GI) is a functional task that challenges the balance control requiring weight shift and a transition from standing to walking. Individuals with Down Syndrome (DS) walk with low velocity, prolonged stance and shorter steps beside an increased support base. However, no studies performed GI analysis on this population. Read More

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http://dx.doi.org/10.1186/s12883-019-1288-4DOI Listing

Brain Activation Changes During Balance- and Attention-Demanding Tasks in Middle- and Older-Aged Adults With Multiple Sclerosis.

Motor Control 2019 Apr 15:1-20. Epub 2019 Apr 15.

4 The University of Alabama at Birmingham.

Functional near-infrared spectroscopy was used to evaluate prefrontal cortex activation differences between older adults with multiple sclerosis (MS) and healthy older adults (HOA) during the performance of a balance- and attention-demanding motor task. Ten older adults with MS and 12 HOA underwent functional near-infrared spectroscopy recording while talking, virtual beam walking, or virtual beam walking while talking on a self-paced treadmill. The MS group demonstrated smaller increases in prefrontal cortex oxygenation levels than HOA during virtual beam walking while talking than talking tasks. Read More

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http://dx.doi.org/10.1123/mc.2018-0044DOI Listing

High Cervical Spinal Cord Stimulation: A One Year Follow-Up Study on Motor and Non-Motor Functions in Parkinson's Disease.

Brain Sci 2019 Apr 3;9(4). Epub 2019 Apr 3.

Department of Biotechnological and Applied Clinical Sciences (DISCAB), University of L'Aquila, 67100 L'Aquila, Italy.

Background: The present study investigated the effectiveness of stimulation applied at cervical levels on pain and Parkinson's disease (PD) symptoms using either tonic or burst stimulation mode.

Methods: Tonic high cervical spinal cord stimulation (T-HCSCS) was applied on six PD patients suffering from low back pain and failed back surgery syndrome, while burst HCSCS (B-HCSCS) was applied in twelve PD patients to treat primarily motor deficits. Stimulation was applied percutaneously with quadripolar or octapolar electrodes. Read More

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http://dx.doi.org/10.3390/brainsci9040078DOI Listing

Incident Mobility Disability, Mild Cognitive Impairment, and Mortality in Community-Dwelling Older Adults.

Neuroepidemiology 2019 Apr 15:1-8. Epub 2019 Apr 15.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

Background/aims: Mobility disability and mild cognitive impairment (MCI) are common in aging and both are associated with risk of death. This study tested the hypothesis that risk of death differs by the order in which mobility disability and MCI occurred.

Methods: One thousand two hundred and sixty-two community-dwelling older adults were unimpaired at baseline and followed annually. Read More

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http://dx.doi.org/10.1159/000499334DOI Listing
April 2019
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Skipping has lower knee joint contact forces and higher metabolic cost compared to running.

Gait Posture 2019 May 28;70:414-419. Epub 2019 Mar 28.

Department of Kinesiology, East Carolina University, 27858, Greenville, NC, United States.

Background: The health benefits of running based exercise programs are plentiful however the high rate of injury in these programs often reduces or eliminates exercise participation. Skipping has shorter steps, reduced vertical ground reaction forces (GRFs), and lower knee extensor torques, compared to running forming the basis of the present hypothesis that skipping would have lower tibio-femoral and patello-femoral joint contact forces.

Research Question: The purpose of this study was to compare knee contact forces between skipping and running at the same speed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183165
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http://dx.doi.org/10.1016/j.gaitpost.2019.03.028DOI Listing
May 2019
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Unsupervised gait retraining using a wireless pressure-detecting shoe insole.

Gait Posture 2019 May 30;70:408-413. Epub 2019 Mar 30.

Department of Orthopedic Surgery, Rush University Medical Center, 1611 W Harrison Street, Suite 201, Chicago, IL 60612, USA. Electronic address:

Background: The knee adduction moment (KAM) is a surrogate measure of mediolateral distribution of loads across the knee joint and is correlated with progression and severity of knee osteoarthritis (OA). Existing biomechanical approaches for unloading the arthritic medial knee compartment vary in their effectiveness in reducing KAM. This study employed a completely wireless, pressure-detecting shoe insole capable of generating auditory feedback via a smartphone. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183170
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http://dx.doi.org/10.1016/j.gaitpost.2019.03.021DOI Listing
May 2019
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Differences in temporal gait mechanics are associated with decreased perceived ankle joint health in individuals with chronic ankle instability.

Gait Posture 2019 May 5;70:403-407. Epub 2019 Apr 5.

University of Kentucky, Lexington, KY, United States.

Background: Chronic ankle instability (CAI) is associated with an increased risk of developing post-traumatic osteoarthritis (PTOA). Altered temporal gait parameters likely contribute to the early development and progression of PTOA in CAI. However, it is unknown if increased clinical symptoms of ankle PTOA influence temporal gait parameters among those with CAI. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2019.03.032DOI Listing

Comparing PIGD and Akinetic-Rigid subtyping of Parkinson Disease and their stability over time.

Eur J Neurol 2019 Apr 15. Epub 2019 Apr 15.

Center for Neurodegenerative Disease-CEMAND, Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, SA, Italy.

Background: Parkinson disease patients are classically classified according to two alternative motor subtyping methods: 1) tremor dominant vs postural instability and gait disorder (PIGD); and 2) tremor dominant vs Akinetic-Rigid.

Objective: We sought to examine: 1) the degree of overlap between the two classification systems at diagnosis of PD, and 2) their temporal stability, as well as the correspondence between the two systems, over a follow-up period 4 years.

Methods: Newly diagnosed, untreated PD patients were classified as tremor-dominant vs PIGD and tremor-dominant vs Akinetic-Rigid at baseline and after 2 and 4 years. Read More

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http://dx.doi.org/10.1111/ene.13968DOI Listing