6,925 results match your criteria Frontiers in Zoology [Journal]


Massive cytoplasmic transport and microtubule organization in fertilized chordate eggs.

Dev Biol 2018 Dec 3. Epub 2018 Dec 3.

Research Institute for Electronic Science, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.

Eggs have developed their own strategies for early development. Amphibian, teleost fish, and ascidian eggs show cortical rotation and an accompanying structure, a cortical parallel microtubule (MT) array, during the one-cell embryonic stage. Cortical rotation is thought to relocate maternal deposits to a certain compartment of the egg and to polarize the embryo. Read More

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December 2018
2 Reads

A giant trichobezoar extracted by laparoscopic and endoscopic cooperative surgery (LECS).

Endosc Int Open 2018 Dec 29;6(12):E1413-E1416. Epub 2018 Nov 29.

Department of Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.

A gastric bezoar is a mass that forms in the stomach. A giant gastric bezoar is particularly difficult to treat medically, and surgical therapy is selected. We describe our experience with a patient who had a giant gastric trichobezoar that was extracted by laparoscopic and endoscopic cooperative surgery (LECS) in accordance with the principles of LECS. Read More

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December 2018
1 Read

Fungi infecting woody plants: emerging frontiers.

Persoonia 2018 Dec 18;40:i-iii. Epub 2018 May 18.

Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria, 0002, South Africa.

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December 2018

Ultrasound-responsive droplets for therapy: A review.

J Control Release 2018 Nov 29. Epub 2018 Nov 29.

Physical Sciences Platform, Sunnybrook Research Institute, Toronto, Canada; Medical Biophysics, University of Toronto, Toronto, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada.

The last two decades have seen the development of acoustically activated droplets, also known as phase-change emulsions, from a diagnostic tool to a therapeutic agent. Through bubble effects and triggered drug release, these superheated agents have found potential applications from oncology to neuromodulation. The aim of this review is to summarise the key developments in therapeutic droplet design and use, to discuss the current challenges slowing clinical translation, and to highlight the new frontiers progressing towards clinical implementation. Read More

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November 2018

Homicides and socio-environmental determinants of health in Brazil: a systematic literature review.

Cad Saude Publica 2018 Nov 29;34(12):e00012818. Epub 2018 Nov 29.

Universidade Regional de Blumenau, Blumenau, Brasil.

Brazil currently has the highest absolute number of homicides in the world, which results from a complex range of factors. This study aimed at understanding the associations between socio-environmental determinants of health (SDH) and homicides in Brazil through a systematic literature review. The review followed PRISMA guidelines, selecting quantitative and qualitative studies published in Portuguese, English, and Spanish carried out between 2002 and 2017, available in the PubMed, MEDLINE, LILACS, SciELO and BVS-BIREME databases. Read More

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November 2018
1 Read

The Mystery of ART.

Mol Reprod Dev 2018 Dec 5. Epub 2018 Dec 5.

Frontiers in Reproduction; Marine Biological Laboratories, University of Chicago, Woods Hole, MA.

One of the first steps towards a successful pregnancy is fertilization, where sperm and oocyte come together to form a zygote. In mammals, this process can occur in vitro, allowing assisted reproductive technologies (ART) to alleviate certain infertilities. ART - which includes in vitro fertilization and gamete donation - accounted for 1. Read More

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December 2018
1 Read

Juvenile Nasal Angiofibroma on 68Ga-PSMA PET/CT: Opening New Frontiers.

Clin Nucl Med 2018 Dec 3. Epub 2018 Dec 3.

Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

The prostate-specific membrane antigen (PSMA) is highly expressed in prostatic cancer. However, PSMA expression is also noted in various benign and malignant nonprostatic neoplasms in the endothelial cells of tumor-associated neovasculature. We performed Ga-PSMA PET/CT in a 14-year-old boy with juvenile nasal angiofibroma (JNA) to explore its theranostic potential. Read More

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December 2018
6 Reads

Erratum: Inhibition of Rumen Methanogens by a Novel Archaeal Lytic Enzyme Displayed on Tailored Bionanoparticles.

Authors:

Front Microbiol 2018 22;9:2982. Epub 2018 Nov 22.

[This corrects the article DOI: 10.3389/fmicb.2018. Read More

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November 2018

Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility.

iScience 2018 Nov 20;10:98-113. Epub 2018 Nov 20.

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

Extracellular signal-regulated kinase (ERK) plays critical roles in T cell development in the thymus. Nevertheless, the dynamics of ERK activity and the role of ERK in regulating thymocyte motility remain largely unknown due to technical limitations. To visualize ERK activity in thymocytes, we here developed knockin reporter mice expressing a Förster/fluorescence resonance energy transfer (FRET)-based biosensor for ERK from the ROSA26 locus. Read More

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November 2018
1 Read

Lactic Acid Bacteria from Argentinean Fermented Foods: Isolation and Characterization for their Potential Use as Starters for Fermentation of Vegetables.

Food Technol Biotechnol 2018 Sep;56(3):398-410

San Pablo Tucumán University, Av. Solano Vera and Villa Nougués, T4129XAK, Tucumán, Argentina.

Lactic acid bacteria (LAB) improve the organoleptic, nutritional and physicochemical properties of artisanal foods. In this study, we selected 31 fermented dairy and vegetable foods marketed in Tucumán city, Argentina, as sources of LAB for the production of pickles. Sixty-four isolates presumptively identified as strains were screened for relevant technological properties for production of fermented foods. Read More

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September 2018
1 Read

Frontiers in Gynecologic Pathology.

Arch Pathol Lab Med 2018 Dec;142(12):1457-1458

From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut (Dr Hui); and the Department of Pathology, Princeton Medical Center, Plainsboro, New Jersey; the Department of Biological Sciences, Rutgers University, Newark, New Jersey; the Department of Chemical Biology, Ernest Mario School of Pharmacy, Piscataway, New Jersey; and Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey (Dr Zhang).

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December 2018
1 Read

Self-assembly on optical fibers: a powerful nanofabrication tool for next generation "lab-on-fiber" optrodes.

Nanoscale 2018 Nov 30. Epub 2018 Nov 30.

Divisione di Optoelettronica, Dipartimento di Ingegneria, Università del Sannio, 82100 Benevento, Italy.

Self-assembly offers a unique resource for the preparation of discrete structures at the nano- and microscale, which are either not accessible by other fabrication techniques or require highly expensive and technologically demanding processes. The possibility of obtaining spontaneous organization of separated components, whether they are molecules, polymers, nano- or micro-objects, into a larger functional unit, enables the development of ready-to-use plug and play devices and components at lower costs. Expanding the applicability of self-assembly approaches at the nanoscale to non-conventional substrates would open up new avenues towards multifunctional platforms customized for specific applications. Read More

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November 2018
1 Read

Frontiers of Medical Micro/Nanorobotics: Applications and Commercialization Perspectives Toward Clinical Uses.

Front Bioeng Biotechnol 2018 14;6:170. Epub 2018 Nov 14.

Texas Materials Institute, The University of Texas at Austin, Austin, TX, United States.

The field of medical micro/nanorobotics holds considerable promise for advancing medical diagnosis and treatment due to their unique ability to move and perform complex task at small scales. Nevertheless, the grand challenge of the field remains in its successful translation towards widespread patient use. We critically address the frontiers of the current methodologies for applications and discuss the current and foreseeable perspectives of their commercialization. Read More

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November 2018
1 Read

Metal Nanoclusters: New Paradigm in Catalysis for Water Splitting, Solar and Chemical Energy Conversion.

ChemSusChem 2018 Nov 28. Epub 2018 Nov 28.

Abstract: Sustainable future extremely demands the innovative breakthroughs in science and technology today especially in the energy sector. Earth-abundant resources can be explored and used to develop renewable and sustainable resources of energy to meet, PAKISTAN.

Sustainable future extremely demands the innovative breakthroughs in science and technology today especially in the energy sector. Earth-abundant resources can be explored and used to develop renewable and sustainable resources of energy to meet the ever increasing global energy demand. The efficient solar-powered conversion systems with the exploitation of cheap and robust catalytic materials for the photo and photo-electro-induced water splitting, photovoltaic cell, fuel cell and renovation of waste products (such as CO2) as chemical fuel are appealing solutions in this quest. Read More

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November 2018
1 Read

Serum miRNA-based prediction of axillary lymph node metastasis in breast cancer.

Clin Cancer Res 2018 Nov 27. Epub 2018 Nov 27.

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute

Purpose: Sentinel lymph node biopsy (SLNB) is the gold-standard procedure for evaluating axillary lymph node (ALN) status in patients with breast cancer. However, the morbidity of SLNB is not negligible, and the procedure is invasive for patients without ALN metastasis. Here, we developed a diagnostic model for evaluating ALN status using a combination of serum microRNAs (miRNAs) and clinicopathological factors as a novel less-invasive biomarker. Read More

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November 2018
3 Reads

The 7th Sino-German Frontiers of Chemistry Symposium - Learning from Nature.

Chem Asian J 2018 Dec 27;13(23):3556-3560. Epub 2018 Nov 27.

Max Planck Institute for Polymer Research, Mainz, 55128, Germany.

Bilateral Symposium: The Technical University, Institute for Advanced Studies, hosted the 7th Sino-German Frontiers of Chemistry Symposium from September 2 to September 6, 2018. This event, co-organized by the Chinese Chemical Society (CCS) and the Gesellschaft Deutscher Chemiker (German Chemical Society), featured excellent talks by the invited early-career chemists of both countries and offered ample opportunities for discussions and making friends among the participants. Read More

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December 2018
1 Read

Moving toward realistic models: Comment on "Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones" by A.V. Belyaev et al.

Phys Life Rev 2018 11 28;26-27:96-99. Epub 2018 Jun 28.

Division of Applied Mathematics, Brown University, 170 Hope Street, Providence, RI 02906, United States of America. Electronic address:

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November 2018
1 Read

Dual-modified natural high density lipoprotein particles for systemic glioma-targeting drug delivery.

Drug Deliv 2018 Nov;25(1):1865-1876

b State Key Laboratory of Toxicology and Medical Countermeasures , Beijing Institute of Pharmacology and Toxicology , Beijing , China.

Therapeutic outcome for the treatment of glioma was often limited due to the two barriers involved: the blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB). Therefore, the development of nanocarriers that possess both BBB and BBTB permeability and glioma-targeting ability is of great importance for the chemotherapy of glioma. New frontiers in nanomedicine are advancing the research of new biomaterials. Read More

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November 2018
1 Read
2.200 Impact Factor

Sulfur Chemistry in Polymer and Materials Science.

Macromol Rapid Commun 2018 Nov 23:e1800650. Epub 2018 Nov 23.

Institute for Biological Interfaces III, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, D-76344, Eggenstein-Leopoldshafen, Germany.

Sulfur and its functional groups are major players in an area of exciting research taking place in modern polymer and materials science, both in academia and industry. In fact, manifold sulfur-based reactions that are both exceptionally versatile as well as tremendously useful have been implemented, and further utilized for the design and preparation of polymeric materials that lead to a plethora of applications ranging from medicine to optics and nanotechnology to separation science. Hence, within this review, an overview of strategies and developments used over the last 5 years to reinforce the importance of the sulfur functional group in modern polymer and materials science is presented. Read More

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November 2018
1 Read

Heterogeneity and Diversity of Striatal GABAergic Interneurons: Update 2018.

Front Neuroanat 2018 8;12:91. Epub 2018 Nov 8.

Center For Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, United States.

Our original review, "Heterogeneity and Diversity of Striatal GABAergic Interneurons," to which this is an invited update, was published in December, 2010 in Frontiers is Neuroanatomy. In that article, we reviewed several decades' worth of anatomical and electrophysiological data on striatal parvalbumin (PV)-, neuropeptide Y (NPY)- and calretinin(CR)-expressing GABAergic interneurons from many laboratories including our own. In addition, we reported on a recently discovered novel tyrosine hydroxylase (TH) expressing GABAergic interneuron class first revealed in transgenic TH EGFP reporter mouse line. Read More

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November 2018
1 Read

Pathogens in space: Advancing understanding of pathogen dynamics and disease ecology through landscape genetics.

Evol Appl 2018 Dec 28;11(10):1763-1778. Epub 2018 Jul 28.

School of Natural Sciences University of Tasmania Hobart Tasmania Australia.

Landscape genetics has provided many insights into how heterogeneous landscape features drive processes influencing spatial genetic variation in free-living organisms. This rapidly developing field has focused heavily on vertebrates, and expansion of this scope to the study of infectious diseases holds great potential for landscape geneticists and disease ecologists alike. The potential application of landscape genetics to infectious agents has garnered attention at formative stages in the development of landscape genetics, but systematic examination is lacking. Read More

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December 2018
1 Read

Erratum: A Class 1 Histone Deacetylase as Major Regulator of Secondary Metabolite Production in .

Authors:

Front Microbiol 2018 9;9:2714. Epub 2018 Nov 9.

[This corrects the article DOI: 10.3389/fmicb.2018. Read More

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November 2018

Annexin A3 gene silencing promotes myocardial cell repair through activation of the PI3K/Akt signaling pathway in rats with acute myocardial infarction.

J Cell Physiol 2018 Nov 19. Epub 2018 Nov 19.

Department of Cardiology, Henan Provincial People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.

Acute myocardial infarction (AMI), as a severe consequence of coronary atherosclerotic heart disease, always contributes to the loss of myocardial cells. Mounting evidence shows that annexin protects the myocardium from ischemic injury. In this study, we examine the inhibition of annexin A3 (ANXA3) on AMI through the phosphatidylinositide 3-kinase/protein kinase B (PI3K/Akt) signaling pathway. Read More

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November 2018
3 Reads

Synthetic RNA-based logic computation in mammalian cells.

Nat Commun 2018 Nov 19;9(1):4847. Epub 2018 Nov 19.

Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.

Synthetic biological circuits are designed to regulate gene expressions to control cell function. To date, these circuits often use DNA-delivery methods, which may lead to random genomic integration. To lower this risk, an all RNA system, in which the circuit and delivery method are constituted of RNA components, is preferred. Read More

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November 2018
2 Reads

Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy.

Cell Stem Cell 2018 Nov 1. Epub 2018 Nov 1.

Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Japan; Facility for iPS Cell Therapy, CiRA, Kyoto University, Kyoto, Japan. Electronic address:

Limited T cell availability and proliferative exhaustion present major barriers to successful T cell-based immunotherapies and may potentially be overcome through the use of "rejuvenated" induced pluripotent stem cells derived from antigen-specific T cells (T-iPSCs). However, strict antigen specificity is essential for safe and efficient T cell immunotherapy. Here, we report that CD8αβ T cells from human T-iPSCs lose their antigen specificity through additional rearrangement of the T cell receptor (TCR) α chain gene during the CD4/CD8 double positive stage of in vitro differentiation. Read More

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November 2018
2 Reads

Neuromuscular organization of the Ctenophore Pleurobrachia bachei.

J Comp Neurol 2018 Nov 17. Epub 2018 Nov 17.

Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, Florida.

Ctenophores are descendants of one of the earliest branching metazoan lineage with enigmatic nervous systems. The lack of convenient neurogenic molecules and neurotransmitters suggests an extensive parallel evolution and independent origins of neurons and synapses. However, the field lags due to the lack of microanatomical data about the neuro-muscular systems in this group of animals. Read More

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November 2018
3 Reads

Outbreak Epidemiology: One of Many New Frontiers of Norovirus Biology.

J Infect Dis 2018 Nov 15. Epub 2018 Nov 15.

Department of Pediatrics, University of Rochester School of Medicine and Dentistry, New York.

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November 2018
1 Read

Random-Length Random Walks and Finite-Size Scaling in High Dimensions.

Phys Rev Lett 2018 Nov;121(18):185701

ARC Centre of Excellence for Mathematical and Statistical Frontiers (ACEMS), School of Mathematical Sciences, Monash University, Clayton, Victoria 3800, Australia.

We address a long-standing debate regarding the finite-size scaling (FSS) of the Ising model in high dimensions, by introducing a random-length random walk model, which we then study rigorously. We prove that this model exhibits the same universal FSS behavior previously conjectured for the self-avoiding walk and Ising model on finite boxes in high-dimensional lattices. Our results show that the mean walk length of the random walk model controls the scaling behavior of the corresponding Green's function. Read More

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November 2018
3 Reads

Generation of 3.9-cycle pulses from the coherent synthesis of two continuous-wave injection seeded optical parametric amplifiers at 53  MHz.

Opt Lett 2018 Nov;43(22):5579-5582

A high repetition-rate, few-cycle light pulse is of great importance due to its potential for a variety of applications, including two-dimensional infrared spectroscopy and time-resolved imaging of molecular structures, which benefit from its ultrabroadband spectrum and ultrashort pulse duration. The generation of an ultrabroadband coherent spectrum is one of the frontiers of ultrafast optics, and accessing such few-cycle pulses is presently under active exploration. Here, we demonstrate a simple yet effective pulse synthesizer. Read More

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November 2018
3 Reads

The Role of the Social Networks, between a Utility and a New Addiction.

Authors:
Annalisa Colucci

Psychiatr Danub 2018 Nov;30(Suppl 7):511-514

Neamente Association, via San Pietro 27, - 80035 Nola (NA), Italy,

The reality of social networks in recent years has taken on new and enriching scenarios, to learn more about the problems and complex dynamics of life that surround the generations of preadolescents and adolescents. This work has matured over several years, interacting with schools in the Campania region (southern Italy), meeting and talking with teachers, parents and students, observing the reality that surrounds them. The territory of Naples and its province was the one in which the activity was mainly carried out. Read More

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November 2018
4 Reads

Enabling an HCV Treatment Revolution and the Frontiers of Solid Solution Formulation.

J Pharm Sci 2018 Nov 12. Epub 2018 Nov 12.

Merck & Co., Inc., West Point, Pennsylvania 19486.

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November 2018
2 Reads

Fighting the Fire of Burnout in Healthcare.

Authors:
Trudy Land

Front Health Serv Manage 2018 ;35(2):1-2

Trudy Land, FACHE, is editor of Frontiers of Health Services Management.

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January 2018
1 Read

Bayesian Methods Might Solve the Problems with Magnitude-based Inference.

Med Sci Sports Exerc 2018 Dec;50(12):2609-2610

Institute of Health and Biomedical Innovation and School of Exercise and Nutrition Sciences Queensland University of Technology Brisbane, Queensland, AUSTRALIA School of Mathematical Sciences and the Australian Research Council Centre of Excellence for Mathematical and Statistical Frontiers Queensland University of Technology Brisbane, Queensland, AUSTRALIA.

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December 2018
4 Reads

Blink synchronization is an indicator of interest while viewing videos.

Int J Psychophysiol 2018 Nov 11;135:1-11. Epub 2018 Nov 11.

Graduate School of Information, Osaka University, Osaka, Japan.

The temporal pattern of spontaneous blinks changes greatly depending on an individual's internal cognitive state. For instance, when several individuals watch the same video, blinks can be synchronized at attentional breakpoints. The present study examined the degree of this blink synchronization, as reflecting an interest level, while viewing various video clips. Read More

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November 2018
1 Read

Atomic-scale imaging of the ferrimagnetic/diamagnetic interface in Au-FeO nanodimers and correlated exchange-bias origin.

Nanoscale 2018 Dec 14;10(45):21499-21508. Epub 2018 Nov 14.

Key Laboratory of Magnetism and Magnetic Materials of the Ministry of Education, School of Physical Science and Technology and Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou 730000, P. R. China.

Exchange-biased magnetic heterostructures have become one of the research frontiers due to their significance in enriching the fundamental knowledge in nanomagnetics and promising diverse applications in the information industry. However, the physical origin of their exchange bias effect is still controversial. A key reason for this is the lack of unequivocal observations of interface growth. Read More

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December 2018
8 Reads
7.390 Impact Factor

New frontiers in antimicrobial leadership: an interview with Joan Butterton.

Future Microbiol 2018 Nov 14. Epub 2018 Nov 14.

Merck & Co, Boston, MA 02115, USA.

The Editor of Future Microbiology speaks to Joan R Butterton, M.D., Associate Vice President and Section Head for Antibacterials and CMV for the Infectious Disease therapeutic area at Merck & Co. Read More

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November 2018
2 Reads

Living at the Frontiers of Life: Extremophiles in Chile and Their Potential for Bioremediation.

Front Microbiol 2018 30;9:2309. Epub 2018 Oct 30.

Laboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química and Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, Valparaíso, Chile.

Extremophiles are organisms capable of adjust, survive or thrive in hostile habitats that were previously thought to be adverse or lethal for life. Chile gathers a wide range of extreme environments: salars, geothermal springs, and geysers located at Altiplano and Atacama Desert, salars and cold mountains in Central Chile, and ice fields, cold lakes and fjords, and geothermal sites in Patagonia and Antarctica. The aims of this review are to describe extremophiles that inhabit main extreme biotopes in Chile, and their molecular and physiological capabilities that may be advantageous for bioremediation processes. Read More

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October 2018
2 Reads

The History and Horizons of Microscale Neural Interfaces.

Micromachines (Basel) 2018 Sep 6;9(9). Epub 2018 Sep 6.

Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Microscale neural technologies interface with the nervous system to record and stimulate brain tissue with high spatial and temporal resolution. These devices are being developed to understand the mechanisms that govern brain function, plasticity and cognitive learning, treat neurological diseases, or monitor and restore functions over the lifetime of the patient. Despite decades of use in basic research over days to months, and the growing prevalence of neuromodulation therapies, in many cases the lack of knowledge regarding the fundamental mechanisms driving activation has dramatically limited our ability to interpret data or fine-tune design parameters to improve long-term performance. Read More

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September 2018
4 Reads

New Frontiers for Cognitive Assessment: An Exploratory Study of the Potentiality of 360° Technologies for Memory Evaluation.

Cyberpsychol Behav Soc Netw 2018 Nov 13. Epub 2018 Nov 13.

1 Clinical and Digital Health Sciences, College of Allied Health Sciences, Augusta University , Augusta, Georgia .

One of the most recent trends in technology field is the 360° technology. In order to investigate its potentiality for the evaluation of memory function, we compared participants' performance in two memory tasks between an encoding delivered through an immersive 360° environment and a non-immersive 360° one. Specifically, we investigated if the immersive 360° environment would facilitate memory encoding in comparison to the non-immersive 360° one. Read More

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November 2018
3 Reads

Polymeric ionically conductive composite matrices and electrical stimulation strategies for nerve regeneration: In vitro characterization.

J Biomed Mater Res B Appl Biomater 2018 Nov 12. Epub 2018 Nov 12.

Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut.

Stem cell strategies and the use of electrical stimulation (ES) represent promising new frontiers for peripheral nerve regeneration. Composite matrices were fabricated by coating electrospun polycaprolactone/cellulose acetate micro-nanofibers with chitosan and ionically conductive (IC) polymers including, sulfonated polyaniline, and lignin sulfonate. These composite matrices were characterized for surface morphology, coating uniformity, ionic conductivity, and mechanical strength to explore as scaffold materials for nerve regeneration in conjunction with ES. Read More

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November 2018
7 Reads

Towards new frontiers in neuroendocrinology: A tribute to Peter H. Seeburg.

Cell Tissue Res 2018 Nov 10. Epub 2018 Nov 10.

Department of Anatomy II, Jena University Hospital, Jena, Germany.

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November 2018
1 Read

Determining Value in Health Technology Assessment: Stay the Course or Tack Away?

Pharmacoeconomics 2018 Nov 9. Epub 2018 Nov 9.

Division of Health Economics, German Cancer Research Center (DKFZ), University of Heidelberg, Heidelberg, Germany.

The economic evaluation of new health technologies to assess whether the value of the expected health benefits warrants the proposed additional costs has become an essential step in making novel interventions available to patients. This assessment of value is problematic because there exists no natural means to measure it. One approach is to assume that society wishes to maximize aggregate health, measured in terms of quality-adjusted life-years (QALYs). Read More

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November 2018
3 Reads

[Frontiers in liver transplantation in indication and techniques].

Chirurg 2018 Nov 9. Epub 2018 Nov 9.

Chirurgische Klinik, Campus Charité Mitte/Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland.

Background: The frontiers in liver transplantation are intrinsically expansions of indications, e.g. hepatocellular carcinoma and (perihilar) cholangiocarcinoma, recipients with more severe concomitant diagnoses or "soft" contraindications and technically demanding reconstruction procedures of vascular structures (for portal vein thrombosis or aorto-hepatic conduits). Read More

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November 2018
2 Reads

Analytical and Quantitative in Vivo Monitoring of Brain Neurochemistry by Electrochemical and Imaging Approaches.

ACS Omega 2018 Oct 16;3(10):13267-13274. Epub 2018 Oct 16.

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences (CAS), Beijing 100190, China.

Quantitative monitoring of brain neurochemistry is aimed at an accurate measurement of chemical basal levels and dynamics defining neuronal activities. Analytical tools must be endowed with high selectivity, sensitivity, and spatiotemporal resolution to tackle this task. On one hand, in vivo electroanalysis combined with miniature electrodes has evolved into a minimally invasive method for probing transient events during neural communication and metabolism. Read More

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October 2018

Erratum: Characterization of the Zebrafish Glycine Receptor Family Reveals Insights Into Glycine Receptor Structure Function and Stoichiometry.

Authors:

Front Mol Neurosci 2018 30;11:395. Epub 2018 Oct 30.

[This corrects the article DOI: 10.3389/fnmol.2018. Read More

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October 2018
1 Read

Decentralized temporal independent component analysis: Leveraging fMRI data in collaborative settings.

Neuroimage 2018 Nov 5;186:557-569. Epub 2018 Nov 5.

University of New Mexico, USA; Mind Research Network, USA.

The field of neuroimaging has recently witnessed a strong shift towards data sharing; however, current collaborative research projects may be unable to leverage institutional architectures that collect and store data in local, centralized data centers. Additionally, though research groups are willing to grant access for collaborations, they often wish to maintain control of their data locally. These concerns may stem from research culture as well as privacy and accountability concerns. Read More

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November 2018
4 Reads

Frontiers and Opportunities: Highlights of the 2 Annual Conference of the Chinese Antibody Society.

Antib Ther 2018 Sep 11;1(2):65-74. Epub 2018 Oct 11.

Laboratory of Molecular Biology, Center for Cancer Research, National Institutes of Health, Bethesda, MD, USA.

The Chinese Antibody Society (CAS) convened the second annual conference in Cambridge, MA, USA on 29 April 2018. More than 600 members from around the world attended the meeting. Invited speakers discussed the latest advancements in therapeutic antibodies with an emphasis on the progress made in China. Read More

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September 2018
5 Reads

New legislation, new frontiers: Indian psychiatrists' perspective of the mental healthcare act 2017 prior to implementation.

Indian J Psychiatry 2018 Jul-Sep;60(3):351-354

Department of Psychiatry, Trinity College Dublin, Trinity Centre for Health Sciences, Tallaght Hospital, Tallaght, Dublin D24 NR0A, Ireland.

Context: The mental healthcare act 2017 represents a complete overhaul of Indian mental health legislation.

Aims: The aim of this study was to establish the opinions of Indian psychiatrists regarding the new act.

Settings: Mental health professionals in Bihar and Jharkhand were interviewed. Read More

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November 2018
1 Read

A Turn-On Detection of DNA Sequences by Means of Fluorescence of DNA-Templated Silver Nanoclusters via Unique Interactions of a Hydrated Ionic Liquid.

Molecules 2018 Nov 6;23(11). Epub 2018 Nov 6.

Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 7-1-20 Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan.

Nucleic acid stability and structure, which are crucial to the properties of fluorescent DNA-templated silver nanoclusters (DNA-Ag NCs), significantly change in ionic liquids. In this work, our purpose was to study DNA-Ag NCs in a buffer containing the hydrated ionic liquid of choline dihydrogen phosphate (choline dhp) to improve fluorescence for application in DNA detection. Due to the stabilisation of an i-motif structure by the choline cation, a unique fluorescence emission-that was not seen in an aqueous buffer-was observed in choline dhp and remained stable for more than 30 days. Read More

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November 2018
1 Read

Biological interactions of biocompatible and water-dispersed MoS nanosheets with bacteria and human cells.

Sci Rep 2018 Nov 6;8(1):16386. Epub 2018 Nov 6.

Department of Physics, "Ettore Pancini", University of Naples "Federico II", Naples, Italy.

Two dimensional materials beyond graphene such as MoS and WS are novel and interesting class of materials whose unique physico-chemical properties can be exploited in applications ranging from leading edge nanoelectronics to the frontiers between biomedicine and biotechnology. To unravel the potential of TMD crystals in biomedicine, control over their production through green and scalable routes in biocompatible solvents is critically important. Furthermore, considering multiple applications of eco-friendly 2D dispersions and their potential impact onto live matter, their toxicity and antimicrobial activity still remain an open issue. Read More

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November 2018
2 Reads
5.080 Impact Factor