150 results match your criteria Friction Blisters


A novel splice-site mutation in the ATP2C1 gene of a Chinese family with Hailey-Hailey disease.

J Cell Biochem 2019 Mar 11;120(3):3630-3636. Epub 2018 Sep 11.

Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Hailey-Hailey disease (HHD), also known as familial benign chronic pemphigus, is an autosomal dominant genodermatosis. It is characterized by erosions, blisters and erythematous plaques at sites of friction or intertriginous areas. The pathogenic gene of HHD has been revealed as the ATPase secretory pathway Ca transporting 1 gene ( ATP2C1), which encodes the protein, secretory pathway Ca /Mn -ATPase 1 (SPCA1). Read More

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http://doi.wiley.com/10.1002/jcb.27640
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http://dx.doi.org/10.1002/jcb.27640DOI Listing
March 2019
11 Reads

Interface-Governed Deformation of Nanobubbles and Nanotents Formed by Two-Dimensional Materials.

Phys Rev Lett 2018 Dec;121(26):266101

Center for Mechanics of Solids, Structures and Materials, Department of Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, Austin, Texas 78712, USA.

Nanoblisters such as nanobubbles and nanotents formed by two-dimensional (2D) materials have been extensively exploited for strain engineering purposes as they can produce self-sustained, nonuniform in-plane strains through out-of-plane deformation. However, deterministic measure and control of strain fields in these systems are challenging because of the atomic thinness and unconventional interface behaviors of 2D materials. Here, we experimentally characterize a simple and unified power law for the profiles of a variety of nanobubbles and nanotents formed by 2D materials such as graphene and MoS_{2} layers. Read More

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http://dx.doi.org/10.1103/PhysRevLett.121.266101DOI Listing
December 2018
2 Reads

Topical sucralfate cream treatment for aplasia cutis congenita with dystrophic epidermolysis bullosa: a case study.

J Wound Care 2018 Nov;27(11):768-771

Associate Professor, Haydarpasa Numune Training and Research Hospital, Department of Pediatric Clinic, Istanbul, Turkey.

Bart syndrome consists of aplasia cutis congenita (ACC) and dominant or recessive dystrophic epidermolysis bullosa (DEB), associated with skin fragility and nail dysplasia. ACC in DEB is thought to be caused by trauma, the most cited cause being in utero formation of bullae consequent to friction of the limbs. Epidermolysis bullosa (EB) refers to a hereditary mechanobullous disease following trauma, characterised by formation of blisters on the skin and mucous membranes. Read More

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http://www.magonlinelibrary.com/doi/10.12968/jowc.2018.27.11
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http://dx.doi.org/10.12968/jowc.2018.27.11.768DOI Listing
November 2018
25 Reads

Basal pharmacokinetic parameters of topically applied diacerein in pediatric patients with generalized severe epidermolysis bullosa simplex.

Orphanet J Rare Dis 2018 Nov 1;13(1):193. Epub 2018 Nov 1.

EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Muellner Hauptstrasse 48, 5020, Salzburg, Austria.

Generalized severe epidermolysis bullosa simplex (EBS-gen sev) is caused by mutations within either the KRT5 or KRT14 gene, phenotypically resulting in blistering and wounding of the skin and mucous membranes after minor mechanical friction. In a clinical phase 2/3 trial, diacerein has recently been shown to significantly reduce blister numbers upon topical application. In this study we addressed basic pharmacokinetic parameters of locally applied diacerein in vitro and in vivo. Read More

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https://ojrd.biomedcentral.com/articles/10.1186/s13023-018-0
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http://dx.doi.org/10.1186/s13023-018-0940-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211505PMC
November 2018
4 Reads

Treatment of Severe Hailey-Hailey Disease With Apremilast.

JAMA Dermatol 2018 Dec;154(12):1453-1456

Department of Dermatology, Université Nice Côte d'Azur, Centre Hospitalier Universitaire Nice, Nice, France.

Importance: Hailey-Hailey disease (HHD) is a rare, autosomal-dominant acantholytic dermatosis characterized clinically by development of recurrent blisters and erosions in friction areas. Despite progression in our understanding of the molecular genetics of HHD, therapy remains suboptimal and there is no known cure.

Objective: To determine whether the novel phosphodiesterase-4 inhibitor apremilast is effective in the treatment of HHD. Read More

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http://dx.doi.org/10.1001/jamadermatol.2018.2191DOI Listing
December 2018
2 Reads

Staphylococcal-scalded skin syndrome: evaluation, diagnosis, and management.

World J Pediatr 2018 04 5;14(2):116-120. Epub 2018 Mar 5.

The Pediatric Institute, Kuala Lumpur General Hospital, Kuala Lumpur, Malaysia.

Background: Staphylococcal-scalded skin syndrome (SSSS), also known as Ritter disease, is a potentially life-threatening disorder and a pediatric emergency. Early diagnosis and treatment is imperative to reduce the morbidity and mortality of this condition. The purpose of this article is to familiarize physicians with the evaluation, diagnosis, and treatment of SSSS. Read More

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http://dx.doi.org/10.1007/s12519-018-0150-xDOI Listing
April 2018
8 Reads

Adhesion, Stiffness, and Instability in Atomically Thin MoS Bubbles.

Nano Lett 2017 09 3;17(9):5329-5334. Epub 2017 Aug 3.

Department of Mechanical Engineering, Boston University , Boston, Massachusetts 02215 United States.

We measured the work of separation of single and few-layer MoS membranes from a SiO substrate using a mechanical blister test and found a value of 220 ± 35 mJ/m. Our measurements were also used to determine the 2D Young's modulus (E) of a single MoS layer to be 160 ± 40 N/m. We then studied the delamination mechanics of pressurized MoS bubbles, demonstrating both stable and unstable transitions between the bubbles' laminated and delaminated states as the bubbles were inflated. Read More

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http://pubs.acs.org/doi/10.1021/acs.nanolett.7b01735
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http://dx.doi.org/10.1021/acs.nanolett.7b01735DOI Listing
September 2017
11 Reads

Prevention of Friction Blisters in Outdoor Pursuits: A Systematic Review.

Wilderness Environ Med 2017 Jun;28(2):139-149

Department of Emergency Medicine, State University of New York Upstate Medical University, Syracuse, NY (Dr Joslin).

The purpose of this systematic review was to determine if sock, antiperspirant, or barrier strategies were effective in prevention of friction blisters in wilderness and outdoor pursuits. A search of PubMed and EMBASE was conducted. Title, abstract, and full text articles were screened by 2 authors using predetermined inclusion and exclusion criteria to identify prospective controlled trials investigating prevention methods for friction blisters involving the foot. Read More

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http://dx.doi.org/10.1016/j.wem.2017.03.007DOI Listing
June 2017
3 Reads

Bullous morphoea: a retrospective study.

Clin Exp Dermatol 2017 Jul 22;42(5):532-535. Epub 2017 May 22.

Section of Dermatology, Mario Aresu Department of Medical Science, University of Cagliari, Cagliari, Italy.

Bullous morphoea is a rare variant of localized scleroderma whose pathogenesis has been widely discussed. We retrospectively reviewed the records of all histopathologically confirmed cases of morphoea followed from 2005 to 2015 at the Dermatology Clinic and Pathology Institute of the University of Cagliari, Sardinia, Italy. Among 137 patients with morphoea, 2 cases of the bullous variant were identified, which were successfully treated with methotrexate. Read More

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http://dx.doi.org/10.1111/ced.13127DOI Listing
July 2017
2 Reads

Nitrous oxide for procedural analgesia at home in a child with epidermolysis bullosa.

Paediatr Anaesth 2017 Jul 11;27(7):776-778. Epub 2017 May 11.

Department of Anesthesia, Clinica Las Condes, Santiago, Chile.

Epidermolysis bullosa comprises a range of conditions characterized by fragile skin with painful blistering induced by minor trauma and friction. The Dowling-Meara variant is a severe form characterized by disseminated painful blistering requiring lifelong skin and wound care. The natural history of the disease is characterized by a chronic course that tends to improve with advancing age. Read More

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http://dx.doi.org/10.1111/pan.13150DOI Listing
July 2017
18 Reads

Effect of CO laser power intensity on the surface morphology and friction behavior of alumina ceramic brackets.

Microsc Res Tech 2017 Aug 3;80(8):923-929. Epub 2017 May 3.

Social Determinants of Health Research Center, University of Medical Sciences, Babol, Iran.

Objective: This study aims at reducing frictional resistance of the ceramic brackets by using CO laser irradiation.

Methods: Forty-two polycrystalline Al O ceramic brackets were randomly divided into six groups of seven samples: a control group B0 (not subjected to laser irradiation) and five groups subjected to irradiation with intensities of 10 (B10), 30 (B30), 70 (B70), 90 (B90), and 110 (B110) J/cm . After irradiation, two samples from each group were evaluated by scanning electron microscopy (SEM) and atomic force microscopy (AFM), while the remaining five samples were tested for frictional resistance. Read More

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http://doi.wiley.com/10.1002/jemt.22883
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http://dx.doi.org/10.1002/jemt.22883DOI Listing
August 2017
20 Reads
1.170 Impact Factor

Anesthetic Management of a Patient With Epidermolysis Bullosa Requiring Major Orthopedic Surgery: A Case Report.

A A Case Rep 2017 Aug;9(3):73-76

From the Department of Anesthesiology, Children's Hospital Colorado, University of Colorado, Aurora, Colorado.

Epidermolysis bullosa (EB) encompasses a wide spectrum of rare genetic disorders in which an abnormality in collagen leads to loss or absence of normal intracellular bridges. Friction or shear forces on the skin and mucosa result in blister, bullae, and scar formation. We present our experience in the management of a patient with EB who required multiple procedures for squamous cell carcinoma of the left arm, including forequarter amputation. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000530DOI Listing
August 2017
24 Reads

First-Aid Treatment for Friction Blisters: "Walking Into the Right Direction?"

Clin J Sport Med 2018 Jan;28(1):37-42

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Objective: Blisters are common foot injuries during and after prolonged walking. However, the best treatment remains unclear. The aim of the study was to compare the effect of 2 different friction blister treatment regimens, wide area fixation dressing versus adhesive tape. Read More

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http://dx.doi.org/10.1097/JSM.0000000000000424DOI Listing
January 2018
14 Reads

[A diabetic patient with blisters].

Ned Tijdschr Geneeskd 2017 ;161:D838

UMC Utrecht, afd. Interne Geneeskunde, Utrecht.

A 64-year-old male suffering from poorly controlled diabetes mellitus type II was evaluated at the outpatient clinic after developing several fluid-filled blisters on his fingers. There was no history of trauma or friction. Eventually, he was diagnosed with bullosis diabeticorum. Read More

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July 2018
3 Reads

Friction Blisters on the Hands Treated Successfully Using 2-Octyl Cyanoacrylate: A Case Report.

J Cutan Med Surg 2017 May/Jun;21(3):253-255. Epub 2016 Nov 4.

2 The Philadelphia Hand Center, P.C., Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Background: Friction blisters on the hand are challenging to treat as conventional dressings are prone to saturation, contamination, and loosening with active hand use and other mechanical stresses. Alternative methods and materials for dressing hand blisters warrant exploration.

Case Summary: A 48-year-old male surgeon presented with friction blisters over his bilateral thumbs. Read More

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http://dx.doi.org/10.1177/1203475416677726DOI Listing
May 2018
6 Reads
0.714 Impact Factor

Atomic intercalation to measure adhesion of graphene on graphite.

Nat Commun 2016 10 31;7:13263. Epub 2016 Oct 31.

Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.

The interest in mechanical properties of two-dimensional materials has emerged in light of new device concepts taking advantage of flexing, adhesion and friction. Here we demonstrate an effective method to measure adhesion of graphene atop highly ordered pyrolytic graphite, utilizing atomic-scale 'blisters' created in the top layer by neon atom intercalates. Detailed analysis of scanning tunnelling microscopy images is used to reconstruct atomic positions and the strain map within the deformed graphene layer, and demonstrate the tip-induced subsurface translation of neon atoms. Read More

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http://dx.doi.org/10.1038/ncomms13263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095517PMC
October 2016
3 Reads

Temperature measurement and control system for transtibial prostheses: Functional evaluation.

Assist Technol 2018 14;30(1):16-23. Epub 2016 Nov 14.

c Department of Orthotics and Prosthetics , University of Social Welfare and Rehabilitation Sciences , Tehran , Iran.

The accumulation of heat inside the prosthetic socket increases skin temperature and fosters perspiration, which consequently leads to high tissue stress, friction blister, discomfort, unpleasant odor, and decreased prosthesis suspension and use. In the present study, the prototype of a temperature measurement and control (TM&C) system was designed, fabricated, and functionally evaluated in a phantom model of the transtibial prosthetic socket. The TM&C system was comprised of 12 thermistors divided equally into two groups that arranged internal and external to a prosthetic silicone liner. Read More

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http://dx.doi.org/10.1080/10400435.2016.1225850DOI Listing
November 2016
29 Reads

Etiological Foundation for Practical Strategies to Prevent Exercise-Related Foot Blisters.

Authors:
Martin D Hoffman

Curr Sports Med Rep 2016 Sep-Oct;15(5):330-5

Department of Physical Medicine & Rehabilitation, Department of Veterans Affairs, Northern California Health Care System; and University of California Davis Medical Center, Sacramento, CA.

This work outlines the etiological factors for exercise-related foot blisters and the pertinent prevention strategies related to these causes. Blisters result from shear forces within the epidermis causing cell necrosis. The extent of skin shear is influenced by friction at the skin and other interfaces, various skin characteristics, bony movement, and the shear modulus of the foot ware. Read More

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http://dx.doi.org/10.1249/JSR.0000000000000297DOI Listing
February 2017
4 Reads

EPIDERMOLYSIS BULLOSA IN THE NEWBORN.

Authors:

J Ayub Med Coll Abbottabad 2016 Jan-Mar;28(1):186-8

We present the case of a new-born baby girl who was delivered at term to a young primigravida mother. The pregnancy was booked late and had no antenatal medical or surgical complications. The baby was born vaginally and had a normal initial examination. Read More

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August 2016
6 Reads

The effect of topical anti blister products on the risk of friction blister formation on the foot.

J Tissue Viability 2016 Aug 29;25(3):167-74. Epub 2016 Apr 29.

Reckitt Benckiser, Dansom Lane, Hull, UK. Electronic address:

Introduction: Foot blisters are a common injury, which can impact on activity and lead to infection. Increased skin surface hydration has been identified as a risk factor for blister formation, indicating that a reduction in hydration could reduce the risk of blister.

Method: Thirty healthy adults were randomised into 3 groups, each receiving a preventative foot blister treatment (2Toms(®) Blister Shield(®); Flexitol(®) Blistop and Boots Anti-Perspirant Foot Spray). Read More

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http://dx.doi.org/10.1016/j.jtv.2016.04.002DOI Listing
August 2016
10 Reads

Hand Blisters in Major League Baseball Pitchers: Current Concepts and Management.

Am J Orthop (Belle Mead NJ) 2016 Mar-Apr;45(3):134-6

St. Louis Cardinals, Springfield, MO; Motion Orthopaedics, Creve Coeur, MO.

Friction blisters are a common sequela of many athletic activities. Their significance can range from minor annoyance to major performance disruptions. The latter is particularly true in baseball pitchers, who sustain repeated trauma between the baseball seams and the fingers of the pitching hand, predominately at the tips of the index and long fingers. Read More

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August 2016
2 Reads

Tribological characterization of zirconia coatings deposited on Ti6Al4V components for orthopedic applications.

Mater Sci Eng C Mater Biol Appl 2016 May;62:643-55

Laboratorio di NanoBiotecnologie - NaBi, Istituto Ortopedico Rizzoli, via di Barbiano 1/10, Bologna, Italy; Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, via di Barbiano 1/10, Bologna, Italy.

One of the most important issues leading to the failure of total joint arthroplasty is related to the wear of the plastic components, which are generally made of ultra high molecular weight polyethylene (UHMWPE). Therefore, the reduction of joint wear represents one of the main challenges the research in orthopedics is called to address nowadays. Surface treatments and coatings have been recognized as innovative methods to improve tribological properties, also in the orthopedic field. Read More

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http://dx.doi.org/10.1016/j.msec.2016.02.014DOI Listing
May 2016
5 Reads

Feasibility, efficacy, and safety of ultrasound-guided axillary plexus blockade in pediatric patients with epidermolysis bullosa dystrophica.

Paediatr Anaesth 2016 Apr 9;26(4):405-8. Epub 2016 Feb 9.

Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Muenster, Muenster, Germany.

Background: In patients suffering from epidermolysis bullosa dystrophica (DEB), the most severe form of epidermolysis bullosa, trauma or friction cause separation of the skin from underlying tissue with consecutive painful blisters, scarifications, contractures, and pseudosyndactyly. To retain functionality of the hands surgical procedures are necessary. Anesthesia is challenging as difficult airways make general anesthesia risky. Read More

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http://dx.doi.org/10.1111/pan.12860DOI Listing
April 2016
3 Reads

Parents' Experiences of Health and Needs When Supporting Their Adolescents With Cerebral Palsy During Transition to Adulthood.

Phys Occup Ther Pediatr 2016 7;36(2):204-16. Epub 2015 Dec 7.

a Department of Health Sciences, Faculty of Medicine , Lund University , Sweden.

Aims: Parents are the primary support providers for adolescents with disabilities, their health and wellbeing is therefore of great importance when planning for youths' transition into adulthood. The aim of this study was to gain a deeper understanding of how parents of adolescents with cerebral palsy (CP) experience their own health and wellbeing and their needs for support during the adolescent's transition to adulthood.

Methods: An inductive qualitative approach was used, including interviews with 15 mothers and fathers to 10 adolescents with CP aged 17-18 years. Read More

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http://dx.doi.org/10.3109/01942638.2015.1101041DOI Listing
December 2016
1 Read

Pressure and Friction Injuries in Primary Care.

Prim Care 2015 Dec 14;42(4):631-44. Epub 2015 Oct 14.

Department of Family and Community Medicine, 500 University Drive, H154, Hershey, PA 17033, USA; Department of Orthopedics and Rehabilitation, 500 University Drive, Hershey, PA 17033, USA; Penn State Primary Care Sports Medicine Fellowship, Department of Family and Community Medicine, Penn State Milton S. Hershey Medical Center, 500 University Drive, H154, Hershey, PA 17033, USA.

Pressure and friction injuries are common throughout the lifespan. A detailed history of the onset and progression of friction and pressure injuries is key to aiding clinicians in determining the underlying mechanism behind the development of the injury. Modifying or removing the forces that are creating pressure or friction is the key to both prevention and healing of these injuries. Read More

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http://dx.doi.org/10.1016/j.pop.2015.07.002DOI Listing
December 2015
14 Reads

Oral Manifestations and Dental Management of Epidermolysis Bullosa Simplex.

Int J Clin Pediatr Dent 2015 Sep-Dec;8(3):239-41. Epub 2015 Sep 11.

Assistant Professor, Institute of Dentistry, Pediatric Dentistry Postgraduate Program, Cruzeiro do Sul University-UNICSUL, Rua Galvao Bueno, Liberdade, Sao Paulo, Brazil.

Epidermolysis bullosa (EB) is a group of hereditary chronic disorders, characterized by fragility of the skin and mucous membranes in response to minor mechanical trauma. The objective of this study was to report the case of a young girl diagnosed with epidermolysis bullosa simplex (EBS), transmitted by an autosomal dominant gene. Cutaneous findings included blisters and dystrophy following minimal friction. Read More

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http://dx.doi.org/10.5005/jp-journals-10005-1321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647048PMC
November 2015
3 Reads

Pattern injuries from blows with the muzzle end of a handgun.

Forensic Sci Int 2015 Dec 13;257:341-346. Epub 2015 Oct 13.

Institute of Forensic Medicine, Freiburg University Medical Centre, Albertstrasse 9, 79104 Freiburg, Germany.

Pistols, revolvers and blank guns are not only used to discharge cartridges, but also for hits to the victim. In such cases, the blows preferably affect the head and/or the interposed hands protecting the body. The impact is mostly exerted either by the grip of a pistol or the butt of a revolver. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03790738150041
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http://dx.doi.org/10.1016/j.forsciint.2015.09.018DOI Listing
December 2015
3 Reads

Blistering Distal Dactylitis in an Adult.

J Cutan Med Surg 2015 Jul-Aug;19(4):397-9. Epub 2015 Mar 3.

Center for Clinical Studies, Houston, TX, USA Dermatological Association of Texas, Houston, TX, USA Department of Dermatology, University of Texas Health Science Center at Houston, Houston, TX, USA.

Background: Blistering distal dactylitis is a localised infection of the anterior pad of the distal phalanx of the digits. It most commonly affects children and uncommonly adults with a history of immunosuppression or trauma.

Objective: A case of blistering distal dactylitis in a 32-year-old male is reported. Read More

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http://dx.doi.org/10.1177/1203475415574971DOI Listing
October 2015
7 Reads

Effectiveness of saltwater baths in the treatment of epidermolysis bullosa.

Pediatr Dermatol 2015 Jan-Feb;32(1):60-3

Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island.

Current management of epidermolysis bullosa (EB) focuses on preventing secondary infections--a leading cause of mortality--by regularly cleaning and bandaging blisters and erosions and preventive bandaging of high-friction areas. Unfortunately the baths and showers used to remove bandages and clean the skin are often painful, causing lack of adherence and subsequent increases in infections, pain, and antimicrobial use. This study evaluates the hypothesis that bathing individuals with EB in saltwater is less painful than in normal bath water. Read More

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http://dx.doi.org/10.1111/pde.12409DOI Listing
October 2015
3 Reads

A prospective randomized blister prevention trial assessing paper tape in endurance distances (Pre-TAPED).

Wilderness Environ Med 2014 Dec 31;25(4):457-61. Epub 2014 Oct 31.

Department of Rehabilitation, Orthopedics and Sports Medicine, University of Washington School of Medicine, Seattle, WA (Dr Krabak).

Objective: Friction foot blisters are a common injury occurring in up to 39% of marathoners, the most common injury in adventure racing, and represent more than 70% of medical visits in multi-stage ultramarathons. The goal of the study was to determine whether paper tape could prevent foot blisters in ultramarathon runners.

Methods: This prospective randomized trial was undertaken during RacingThePlanet 155-mile (250-km), 7-day self-supported ultramarathons in China, Australia, Egypt, Chile, and Nepal in 2010 and 2011. Read More

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http://dx.doi.org/10.1016/j.wem.2014.06.013DOI Listing
December 2014
7 Reads

Combined therapeutic use of oral alitretinoin and narrowband ultraviolet-B therapy in the treatment of hailey-hailey disease.

Dermatol Reports 2014 Feb 3;6(1):5604. Epub 2014 Nov 3.

Behavioural Neuroscience Program, Laurentian University , Greater Sudbury, Canada ; Department of Biomolecular Sciences, Laurentian University , Greater Sudbury, Canada.

Hailey-Hailey disease (HHD) is a chronic familial bullous disease characterized by recurrent blisters and erosions typically at friction-prone areas of the body accompanied by acantholysis upon histologic examination. There are a number of therapies used in the management of HHD. Its symptoms have been effectively treated with antimicrobial therapies, corticosteroids and other agents such as cyclosporine and prednisone. Read More

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http://dx.doi.org/10.4081/dr.2014.5604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224006PMC
February 2014
3 Reads

Epidermolysis bullosa, dental and anesthetic management: a case report.

J Dent (Shiraz) 2014 Sep;15(3):147-52

Instructor of Child Neurology and Neurodevelopmental Disabilities. UMDNJ/ Robert Wood Johnson Medical School, NJ, USA.

Epidermolysis bullosa (EB) is a group of rare inherited skin and mucous membrane disorders in which blister formation may arise spontaneously or following a minor friction. Various patterns of inheritance are explicated for the disease. The disease has a profound effect on oral mucosa and may result in high prevalence of dental caries. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149898PMC
September 2014
4 Reads

Prevention of foot blisters.

Authors:
Joseph J Knapik

J Spec Oper Med 2014 ;14(2):95-7

Foot blisters are the most common medical problem faced by Soldiers during foot march operations and, if untreated, they can lead to infection. Foot blisters are caused by boots rubbing on the foot (frictional forces), which separates skin layers and allows fluid to seep in. Blisters can be prevented by wearing properly sized boots, conditioning feet through regular road marching, wearing socks that reduce reduce friction and moisture, and possibly applying antiperspirants to the feet. Read More

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July 2016
7 Reads

The effect of hydration on the risk of friction blister formation on the heel of the foot.

Skin Res Technol 2014 May 20;20(2):246-53. Epub 2014 Mar 20.

School of Health Sciences, Centre for Health Sciences Research, University of Salford, Manchester, UK.

Background: Friction blister research has focused on prevention and treatment approaches rather than exploring the pathophysiology of the friction blister. Increased skin hydration has been purported to be a key risk factor in friction blister development. This study aimed to test the effect of increased skin surface hydration on the risk of friction blister creation. Read More

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http://doi.wiley.com/10.1111/srt.12136
Publisher Site
http://dx.doi.org/10.1111/srt.12136DOI Listing
May 2014
5 Reads

Injuries associated with the 580 km university student grand voluntary road march: focus on foot injuries.

J Korean Med Sci 2013 Dec 26;28(12):1814-21. Epub 2013 Nov 26.

Department of Emergency Medicine, Ajou University School of Medicine and Ajou University Hospital, Suwon, Korea.

College student volunteers (n = 142) completed a 580 km road march for 21 consecutive days. Each volunteer carried a backpack that weighed 14.1 ± 1. Read More

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http://dx.doi.org/10.3346/jkms.2013.28.12.1814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857380PMC
December 2013
11 Reads

Graphene blisters with switchable shapes controlled by pressure and adhesion.

Nano Lett 2013 26;13(12):6216-21. Epub 2013 Nov 26.

Department of Mechanical Engineering, University of Colorado , Boulder, Colorado 80309, United States.

We created graphene blisters that cover and seal an annular cylinder-shaped microcavity in a SiO2 substrate filled with a gas. By controlling the pressure difference between the gas inside and outside of the microcavity, we switch the graphene membrane between multiple stable equilibrium configurations. We carried out experiments starting from the situation where the pressure of the gas inside and outside of the microcavity is set equal to a prescribed charging pressure, p0 and the graphene membrane covers the cavity like an annular drum, adhered to the central post and the surrounding substrate due to van der Waals forces. Read More

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http://dx.doi.org/10.1021/nl4036324DOI Listing
September 2014
5 Reads

[Betadine in the care of friction blisters. Treatment protocol in primary health care].

Rev Enferm 2013 Jun;36(6):24-31

Servicios de Primeros Auxilios, Sociedad de Prevención Asepeyo, Reinosa, Cantabria.

First prize in the VII edition of the award winning work Betadine for nursing 2012. The dermatitis caused by repeated friction or trauma to the skin are very common in the population, mainly in athletes. The action of shear forces on the skin makes intradermal blisters very painful; being foot the areas more prone to its occurrence and local infection, one of the most common complications during its evolution. Read More

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June 2013
5 Reads

Inherited epidermolysis bullosa: clinical and therapeutic aspects.

An Bras Dermatol 2013 Mar-Apr;88(2):185-98

Federal University of Bahia (UFBA), Salvador, BA, Brazil.

Inherited epidermolysis bullosa (EB) is a heterogeneous group of genetic disorders that present with skin and, in some cases, mucosal fragility, predisposing patients to the development of blisters and/or erosions after minimal trauma or friction. Children with a recurrent history of these kinds of lesions or neonates that present them in the absence of another reasonable explanation should be investigated. Diagnosis must be based on clinical and histopathological findings. Read More

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http://dx.doi.org/10.1590/S0365-05962013000200001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750879PMC
March 2014
10 Reads

[Neonatal hereditary dystrophic epidermolysis bullosa: a genetically diagnosed case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2013 Apr;45(2):202-6

Department of Pediatrics, Beijing University First Hospital, China.

Objective: To investigate the diagnostic value of clinical manifestations, pathologic findings of skin biopsies and genetic testing in the diagnosis of neonatal hereditary dystrophic epidermolysis bullosa.

Methods: Here we reported one case of hereditary dystrophic epidermolysis bullosa with neonatal onset, and explored the clinical and pathological features,as well as the genetic diagnosis,of the disease process.

Results: The neonate was born with large areas of skin damage and erosion, extending to the left ankle and foot, and was admitted to the hospital 10 hours after birth. Read More

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April 2013
1 Read

[Acute skin detachment in a newborn].

Ned Tijdschr Geneeskd 2013 ;157(11):A5272

UMC Groningen, afd. Dermatologie, Centrum voor blaarziekten, Groningen, the Netherlands.

Acute blistering and erosion in a newborn is one of the few emergency cases seen in dermatology. It is important to differentiate between infectious causes, congenital abnormalities, autoimmune bullous dermatitis, immunological skin diseases and skin burns within 24 hours. In this clinical lesson, we present a case of acute skin detachment in a newborn caused by staphylococcal scalded skin syndrome (SSSS). Read More

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April 2013
5 Reads

Access to wound dressings for patients living with epidermolysis bullosa - an Australian perspective.

Authors:
Louise J Stevens

Int Wound J 2014 Oct 22;11(5):505-8. Epub 2012 Nov 22.

Professional Nursing Practice, Dip Higher Ed in Nursing (Adult/Child), Clinical Nurse Consultant, National Epidermolysis Bullosa Dressings Scheme, Brightsky Australia, Newington, NSW, Australia.

Epidermolysis Bullosa (EB) is a rare genetic skin disorder characterised by fragility and blistering of skin and mucous membranes. Skin can blister and shear away from minimal friction, trauma and every day activities. The disease causes a wide range of complications but wound care is the major challenge to severe EB, and good wound care is an essential part of wound management. Read More

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http://dx.doi.org/10.1111/j.1742-481X.2012.01116.xDOI Listing
October 2014
13 Reads

The formation of friction blisters on the foot: the development of a laboratory-based blister creation model.

Skin Res Technol 2013 Feb 14;19(1):e479-89. Epub 2012 Aug 14.

Centre for Health Sciences Research, University of Salford, Manchester, UK.

Background/purpose: Friction blisters on the foot are a debilitating pathology that have an impact on activities of daily living and can severely impair function. The purpose of this study was to test the hypotheses that digital infrared thermographic imaging will reveal: 1) a correlation between load application to the skin and the creation of blisters, and 2) a correlation between thermographic readings and contact thermometric temperatures.

Methods: Apparatus was developed to cause the formation of heel blisters through controlled load application (70 kPa). Read More

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http://doi.wiley.com/10.1111/j.1600-0846.2012.00669.x
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http://dx.doi.org/10.1111/j.1600-0846.2012.00669.xDOI Listing
February 2013
5 Reads

[An infant with blisters post partum].

Ned Tijdschr Geneeskd 2012 ;156(18):A3076

Ziekenhuisgroep Twente, afd. Kindergeneeskunde, Almelo, the Netherlands.

A newborn boy was sent to the hospital immediately after birth because of pre-auricular vesicles on both cheeks. There were no other congenital anomalies. First we thought the lesions were caused by friction or by impetigo bullosa. Read More

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June 2012
4 Reads

Blisters on the battlefield: the prevalence of and factors associated with foot friction blisters during Operation Iraqi Freedom I.

Mil Med 2012 Feb;177(2):157-62

Seacoast Orthopedics & Sports Medicine, 7 Marsh Brook Drive, Somersworth, NH 03878, USA.

Background: Foot friction blisters in military personnel lessen a soldier's mobility, concentration, and critical decision-making skills.

Objective: To determine the prevalence of and factors associated with friction blisters during deployment in all military personnel who nonurgently presented to the 28th Combat Support Hospital.

Methods: A cross-sectional survey was performed at the 28th Combat Support Hospital. Read More

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February 2012
3 Reads

The effect of two sock fabrics on perception and physiological parameters associated with blister incidence: a field study.

Ann Occup Hyg 2012 May 23;56(4):481-8. Epub 2012 Jan 23.

Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Protection and Physiology, St. Gallen, Switzerland.

The goal of the present study was to investigate differences in perception and skin hydration at the foot of two sock fabrics with distinct moisture properties in a realistic military setting. Thirty-seven military recruits wore two different socks (PP: 99.6% polypropylene and 0. Read More

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https://academic.oup.com/annweh/article/56/4/481/168464/The-
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http://dx.doi.org/10.1093/annhyg/mer127DOI Listing
May 2012
4 Reads

Skin conditions in figure skaters, ice-hockey players and speed skaters: part I - mechanical dermatoses.

Sports Med 2011 Sep;41(9):709-19

Department of Dermatology, Columbia University Medical Center, New York, NY 10032, USA.

Figure skaters, ice-hockey players and speed skaters experience a range of dermatologic conditions and tissue-related injuries on account of mechanical trauma, infectious pathogens, inflammatory processes and environmental factors related to these competitive pursuits. Sports medicine practitioners, family physicians, dermatologists and coaches should be familiar with these skin conditions to ensure timely and accurate diagnosis and management of affected athletes. This review is Part I of a subsequent companion review and provides a comprehensive review of mechanical dermatoses experienced by ice-skating athletes, including skater's nodules and its variants, pump bumps, piezogenic pedal papules, talon noir, skate/lace bite, friction bullae, corns and calluses, onychocryptosis, skater's toe and skate blade-induced lacerations. Read More

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http://link.springer.com/10.2165/11590540-000000000-00000
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http://dx.doi.org/10.2165/11590540-000000000-00000DOI Listing
September 2011
34 Reads

Blisters and homeopathy: case reports and differential diagnosis.

Homeopathy 2011 Jul;100(3):168-74

Asociaţia Română de Homeopatie Clinică, Timişoara, Romania.

Blisters are skin lesions characterized by accumulation of fluid between the layers of the skin. Their severity varies from the common blisters caused by friction to severe autoimmune and congenital bullous disorders, some of them currently without treatment in conventional medicine or requiring drugs with potentially severe side-effects. This article reports cases of blistering diseases successfully treated with homeopathic medicines, which represent an alternative for the treatment of such disorders. Read More

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http://linkinghub.elsevier.com/retrieve/pii/S147549161100041
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http://dx.doi.org/10.1016/j.homp.2011.02.014DOI Listing
July 2011
8 Reads

The effect of two sock fabrics on physiological parameters associated with blister incidence: a laboratory study.

Ann Occup Hyg 2011 Jun;55(5):510-8

Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Protection and Physiology, St Gallen, Switzerland.

The goal of the present study was to investigate physiological effects, mainly at the level of the foot, of two sock fabrics with distinct moisture properties. Twelve participants wore two different socks, one on each foot. The following two sock types were used: PP: 99. Read More

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http://dx.doi.org/10.1093/annhyg/meq099DOI Listing
June 2011
4 Reads

Investigation of the influence of textiles and surface treatments on blistering using a novel simulant.

Skin Res Technol 2012 Feb 21;18(1):94-100. Epub 2011 Apr 21.

L-3 Communications, Waco, TX, USA.

Background: Friction blisters occur when shear loading causes the separation of dermal layers. Consequences range from minor pain to life-threatening infection. Past research in blister formation has focused on in vivo experiments, which complicate a mechanics-based study of the phenomenon. Read More

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http://doi.wiley.com/10.1111/j.1600-0846.2011.00538.x
Publisher Site
http://dx.doi.org/10.1111/j.1600-0846.2011.00538.xDOI Listing
February 2012
5 Reads