170 results match your criteria Friction Blisters

A Brief Review on Factors Affecting the Tribological Interaction between Human Skin and Different Textile Materials.

Materials (Basel) 2022 Mar 16;15(6). Epub 2022 Mar 16.

Department of Mechanical Engineering, University of Nevada, Reno, NV 89557, USA.

The application of tribology is not just limited to mechanical components of engineering systems. As a matter of fact, the understanding of friction and wear can be applied to everyday life. One of the important fields is skin tribology, as human skin interacts with various surfaces of different materials. Read More

View Article and Full-Text PDF

The influence of sock composition on the appearance of foot blisters in hikers.

J Tissue Viability 2022 Feb 4. Epub 2022 Feb 4.

Department of Nursing, University of Extremadura, Plasencia, Spain. Electronic address:

Introduction: Socks are of fundamental importance in reducing friction and in controlling the temperature and humidity of the foot, thus preventing the appearance of blisters. However, the influence of sock fibres (synthetic vs. natural) on blistering during long-distance hiking has received little research attention. Read More

View Article and Full-Text PDF
February 2022

Diagnosis, imaging, and potential morbidities of the hallux interphalangeal joint os interphalangeus.

Skeletal Radiol 2022 Jun 26;51(6):1143-1151. Epub 2021 Oct 26.

Department of Radiology, Temple University Hospital, Philadelphia, PA, USA.

Hallux pain is a common entity with a differential diagnoses including hallux valgus, hallux limitus/rigidus, and gout and specifically at the interphalangeal joint (IPJ), flexor hallucis longus (FHL) tenosynovitis, and joint arthrosis. An under-recognized source of pain is the os interphalangeus, an ossicle typically located at the plantar aspect of the hallucal interphalangeal joint. This ossicle is radiographically visible in its ossified form in 2-13% of individuals, but can also be present as an ossified or non-ossified nodule in patients. Read More

View Article and Full-Text PDF

Clinical evidence of the nursing diagnosis Adult pressure injury.

Rev Esc Enferm USP 2021 24;55:e20210106. Epub 2021 Sep 24.

Universidade Federal do Rio Grande do Sul, Escola de Enfermagem, Porto Alegre, RS, Brazil.

Objective: To identify clinical evidence of the nursing diagnosis Adult pressure injury.

Method: Cross-sectional study with 138 adult patients, with community-acquired or hospital-acquired pressure injuries, admitted to clinical, surgical, and intensive care units. Data collected from Electronic health records (EHR) and from the clinical assessment of patients at the bedside, analyzed through descriptive statistics. Read More

View Article and Full-Text PDF
October 2021

Physiotherapy for epidermolysis bullosa: clinical practice guidelines.

Orphanet J Rare Dis 2021 09 30;16(1):406. Epub 2021 Sep 30.

Department of Rehabilitation Services, Stanford Children's Health, 321 Middlefield Road, Menlo Park, CA, 94025, USA.

Epidermolysis bullosa (EB) is characterized by skin fragility with blister formation occurring spontaneously or following minor trauma such as gentle pressure or friction. Current physiotherapy practice is based on anecdotal care, clinical expertise and creative problem solving with caregivers and individuals with EB. Evidence based intervention is needed to establish a foundation of knowledge and to guide international practitioners to create and improve standards of care to effectively work with individuals living with EB. Read More

View Article and Full-Text PDF
September 2021

Symmetrical Skin Lesions on the Gluteal Region in a Patient with Anti-Laminin-332 Mucous Membrane Pemphigoid.

Acta Dermatovenerol Croat 2021 Jul;29(2):105-107

Nobuki Maki; MD, Department of Dermatology Akita National Hospital, 84-40 Idonosawa, Iwakiuchimichikawa, Yurihonjo, Akita 018-1393 Japan;

Mucous membrane pemphigoid (MMP), previously called cicatricial pemphigoid, is a rare subepidermal immunobullous disorder that primarily affects the mucous membranes (1,2). MMP is divided into two major subtypes, anti-BP180-type MMP and anti-laminin-332 (previously called laminin 5 or epiligrin) MMP. Anti-laminin-332 MMP is known to be associated with malignant tumors (3), which may cause overexpression of autoantibodies and induce autoimmunity to laminin-332 (4). Read More

View Article and Full-Text PDF

Anesthetic Management of Adults With Epidermolysis Bullosa.

Anesth Analg 2022 01;134(1):90-101

From the Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Stanford, California.

Epidermolysis bullosa (EB) is a group of rare, inherited diseases characterized by skin fragility and multiorgan system involvement that presents many anesthetic challenges. Although the literature regarding anesthetic management focuses primarily on the pediatric population, as life expectancy improves, adult patients with EB are more frequently undergoing anesthesia in nonpediatric hospital settings. Safe anesthetic management of adult patients with EB requires familiarity with the complex and heterogeneous nature of this disease, especially with regard to complications that may worsen during adulthood. Read More

View Article and Full-Text PDF
January 2022

Two Novel Variants and One Previously Reported Variant in the Gene in Chinese Hailey-Hailey Disease Patients.

Mol Syndromol 2021 Jun 4;12(3):148-153. Epub 2021 May 4.

Department of Dermatology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

Hailey-Hailey disease (HHD) is a rare autosomal dominant genodermatosis. It is characterized clinically by recurrent erosions, blisters and erythematous plaques at the sites of friction and intertriginous areas. The pathogenic gene of HHD was reported to be the ATPase calcium-transporting type 2C member 1 gene (). Read More

View Article and Full-Text PDF

Nondestructive Quantitative Evaluation of Yarns and Fabrics and Determination of Contact Area of Fabrics Using the X-ray Microcomputed Tomography System for Skin-Textile Friction Analysis.

ACS Appl Mater Interfaces 2021 Jan 11;13(3):4652-4664. Epub 2021 Jan 11.

Wilson College of Textiles, North Carolina State University, Raleigh, North Carolina 27606, United States.

In different mechanical conditions, repetitive friction in combination with pressure, shear, temperature, and moisture leads to skin discomfort and imposes the risks of developing skin injuries such as blisters and pressure ulcers, frequently reported in athletes, military personnel, and in people with compromised skin conditions and/or immobility. Textiles next to skin govern the skin microclimate, have the potential to influence the mechanical contact with skin, and contribute to skin comfort and health. The adhesion-friction theory suggests that contact area is a critical factor to influence adhesion, and therefore, friction force. Read More

View Article and Full-Text PDF
January 2021

Pool Toes: Case Report and Review of Pool-Associated Pedal Dermatoses.

Philip R Cohen

Cureus 2020 Nov 28;12(11):e11756. Epub 2020 Nov 28.

Dermatology, San Diego Family Dermatology, National City, USA.

Pool swimmers are susceptible to pedal dermatoses. The causes for these conditions are asteototic dermatitis, contact dermatitis, friction-induced injury, infections, keratoderma, pruritus, thermal injury, ultraviolet radiation exposure, and urticaria. The specific dermatoses include aquagenic keratoderma, aquagenic pruritus, aquagenic urticaria, cold-induced urticaria, contact urticaria, erosion interdigitalis blastomycetica, erythrasma, Mycobacterium abscessus hand and foot disease, onychomycosis, photosensitivity, pitted keratolysis, plantar verruca, pool dermatitis, pool feet, pool toes, pool water dermatitis, pseudomonas hot-foot syndrome, skin cancer, subcorneal hematoma, sunburn, swim fin dermatitis, tinea pedis, toe web infection, and xerosis. Read More

View Article and Full-Text PDF
November 2020

Recurrent Ulcerations in an 84-Year-Old Male Diagnosed with Hailey-Hailey Disease.

Case Rep Dermatol 2020 Sep-Dec;12(3):209-212. Epub 2020 Nov 5.

Department of Pathology, Royal Medical Services, Riffa, Bahrain.

Hailey-Hailey disease (HHD), or familial benign chronic pemphigus, is a rare inherited acantholytic dermatosis. It is an autosomal dominant disease affecting the intertriginous areas. HHD has been characterized by flaccid blisters, erosions, and macerations that are limited to flexural (friction-prone) areas. Read More

View Article and Full-Text PDF
November 2020

Prophylactic Dressings for Maintaining Skin Integrity of Healthcare Workers When Using N95 Respirators While Preventing Contamination Due to the Novel Coronavirus: A Quality Improvement Project.

J Wound Ostomy Continence Nurs 2020 Nov/Dec;47(6):551-557

Michelle Pacis, BSN, RN, CWOCN, Department of Wound, Ostomy and Continence, Cedars-Sinai Medical Center, Los Angeles, California.

Purpose: Extended use of N95 respirator masks is far more prevalent during the coronavirus disease 2019 (COVID-19) pandemic. As WOC nurses, we were tasked with formulating procedures for protecting the facial skin integrity of healthcare workers (HCWs) using personal protective devices when caring for patients with suspected or active COVID-19, while avoiding contamination when the masks are donned or doffed. This quality improvement project describes how we approached this project within the limited time frame available as we cared for patients with established and suspected COVID-19. Read More

View Article and Full-Text PDF
November 2020

Optimize General Anesthesia for a Dystrophic Epidermolysis Bullosa Patient That Cannot Be Intubated.

Asian J Anesthesiol 2020 09 24;58(3):111-114. Epub 2020 Jul 24.

Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Dystrophic epidermolysis bullosa (DEB) is a rare genetic skin disease characterized by blisters and ulcers on the skin and mucosa after minor friction. The risk of invasive squamous cell carcinoma on the unhealed ulcers increases with age. Tracheal intubation during general anesthesia may induce tracheal stricture due to blister formation and/or scarring in DEB patients and cause severe airway obstruction. Read More

View Article and Full-Text PDF
September 2020

Exploring the Mechanism for Blister Prevention Using Moleskin.

Curr Sports Med Rep 2020 Nov;19(11):451-453

Esperance Podiatry (private practice); BlisterPod Pty Ltd and BlisterPod LLC, Esperance, WA, Australia.

Moleskin is a commonly used material in podiatry and sports medicine for blister prevention and treatment. Common understanding regarding its protective mechanism is reduction of friction at the interface between the foot and the sock/shoe. We argue that moleskin may actually increase friction at this interface, but nonetheless prevents blisters by dispersing shear load within the skin across a wider surface area, reducing potential for skin damage. Read More

View Article and Full-Text PDF
November 2020

COVID-19: An overview for dermatologists.

Int J Dermatol 2020 Dec 27;59(12):1437-1449. Epub 2020 Oct 27.

Cardiff University, Cardiff, Wales, UK.

Numerous unexplained pneumonia cases were reported to the World Health Organization (WHO) by Wuhan, China, in December 2020. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a zoonotic pathogen, came into sight, spreading coronavirus disease 2019 (COVID-19) all over the globe. Association of cutaneous signs and symptoms with COVID-19 is being studied worldwide, principally, to determine if these dermatoses can help in early recognition of SARS-CoV-2 infection. Read More

View Article and Full-Text PDF
December 2020

Do Athletes Practicing Outdoors Know and Care Enough About the Importance of Photoprotection?

Acta Dermatovenerol Croat 2020 Jul;28(1):41-42

Prof. Marija Buljan, MD, PhD, Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Centre, Vinogradska 29, 10000 Zagreb, Croatia;

Athletes practicing and competing outdoors are exposed to considerable UV radiation and at an increased risk for the development of UV-related skin conditions, including skin cancer. Risk factors for skin cancer include genetics, immune status, and particularly UV radiation. Independent factors, such as phototype, family or personal history of melanoma, number of nevi, atypical nevi and solar lentigines, as well as sunburn history are also important risk indicators for skin cancer, especially melanoma (1-3). Read More

View Article and Full-Text PDF

Oral rehabilitation with dental implants in patients with recessive dystrophic epidermolysis bullosa: A retrospective study with 2-15 years of follow-up.

Med Oral Patol Oral Cir Bucal 2020 Mar 1;25(2):e262-e267. Epub 2020 Mar 1.

Background: Epidermolysis bullosa (EB) comprises a group of hereditary disorders characterized by mechanical fragility of the skin and mucous membranes, with the development of blisters and vesicles in response to minimum tissue friction. Recessive dystrophic epidermolysis bullosa (RDEB) with generalized involvement is the most common subtype in the oral cavity. The present study was carried out to investigate dental implant survival, peri-implant tissue condition, patient satisfaction, and the impact of treatment upon the quality of life of patients with RDEB rehabilitated with implants and full-arch implant-supported prostheses. Read More

View Article and Full-Text PDF

Friction Blister by Climbing Harness: A Case Report.

Wilderness Environ Med 2019 Sep 20;30(3):302-305. Epub 2019 Jun 20.

Mountain Medicine Society of Nepal, Kathmandu, Nepal; Kristi Primary Health Center, Pokhara, Nepal.

An experienced 24-y-old climber on Mount Everest presented to the Base Camp medical clinic with a friction blister on his right flank. The blister was filled with clear fluid and was located about 3 cm posterior and 3 cm superior to the highest point of the right iliac crest, the site where a climbing harness would support the climber while hanging. A diagnosis of friction blister caused by a climbing harness used while traversing between Camp 2 and Camp 3 of Mount Everest was made. Read More

View Article and Full-Text PDF
September 2019

Evaluation of the extent of damage to the esophageal wall caused by press-through package ingestion.

PeerJ 2019 18;7:e6763. Epub 2019 Apr 18.

Department of Research and Development of Next Generation Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.

Press-through package (PTP) is the most common accidentally ingested foreign body in Japan. Accidental ingestion of PTP can result in esophageal damage. An approach for evaluating the risk of esophageal injury has not been established. Read More

View Article and Full-Text PDF

Orofacial management for epidermolysis bullosa during wisdom tooth removal surgery: A technical note.

J Stomatol Oral Maxillofac Surg 2019 Nov 22;120(5):467-470. Epub 2019 Mar 22.

Department of maxillofacial surgery, university institute of the face and neck, university hospital of Nice, 31, avenue de Valombrose, 06100 Nice, France. Electronic address:

Introduction: Epidermolysis bullosa (EB) is a heterogeneous group of genetic diseases characterized by cutaneous and/or mucosal fragility. Blisters can occur spontaneously or because of minor friction on facial skin or the oral cavity. The repercussions of these dermatoses complicate the management of patients during surgery; for example, wisdom teeth removal might be complicated because of the limited mouth opening and mucosal lesions may be aggravated when the area of the wisdom teeth is being explored. Read More

View Article and Full-Text PDF
November 2019

A novel splice-site mutation in the ATP2C1 gene of a Chinese family with Hailey-Hailey disease.

J Cell Biochem 2019 03 11;120(3):3630-3636. Epub 2018 Sep 11.

Center for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Hailey-Hailey disease (HHD), also known as familial benign chronic pemphigus, is an autosomal dominant genodermatosis. It is characterized by erosions, blisters and erythematous plaques at sites of friction or intertriginous areas. The pathogenic gene of HHD has been revealed as the ATPase secretory pathway Ca transporting 1 gene ( ATP2C1), which encodes the protein, secretory pathway Ca /Mn -ATPase 1 (SPCA1). Read More

View Article and Full-Text PDF

Interface-Governed Deformation of Nanobubbles and Nanotents Formed by Two-Dimensional Materials.

Phys Rev Lett 2018 Dec;121(26):266101

Center for Mechanics of Solids, Structures and Materials, Department of Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, Austin, Texas 78712, USA.

Nanoblisters such as nanobubbles and nanotents formed by two-dimensional (2D) materials have been extensively exploited for strain engineering purposes as they can produce self-sustained, nonuniform in-plane strains through out-of-plane deformation. However, deterministic measure and control of strain fields in these systems are challenging because of the atomic thinness and unconventional interface behaviors of 2D materials. Here, we experimentally characterize a simple and unified power law for the profiles of a variety of nanobubbles and nanotents formed by 2D materials such as graphene and MoS_{2} layers. Read More

View Article and Full-Text PDF
December 2018

Topical sucralfate cream treatment for aplasia cutis congenita with dystrophic epidermolysis bullosa: a case study.

J Wound Care 2018 11;27(11):768-771

Associate Professor, Haydarpasa Numune Training and Research Hospital, Department of Pediatric Clinic, Istanbul, Turkey.

Bart syndrome consists of aplasia cutis congenita (ACC) and dominant or recessive dystrophic epidermolysis bullosa (DEB), associated with skin fragility and nail dysplasia. ACC in DEB is thought to be caused by trauma, the most cited cause being in utero formation of bullae consequent to friction of the limbs. Epidermolysis bullosa (EB) refers to a hereditary mechanobullous disease following trauma, characterised by formation of blisters on the skin and mucous membranes. Read More

View Article and Full-Text PDF
November 2018

Basal pharmacokinetic parameters of topically applied diacerein in pediatric patients with generalized severe epidermolysis bullosa simplex.

Orphanet J Rare Dis 2018 11 1;13(1):193. Epub 2018 Nov 1.

EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology, University Hospital of the Paracelsus Medical University Salzburg, Muellner Hauptstrasse 48, 5020, Salzburg, Austria.

Generalized severe epidermolysis bullosa simplex (EBS-gen sev) is caused by mutations within either the KRT5 or KRT14 gene, phenotypically resulting in blistering and wounding of the skin and mucous membranes after minor mechanical friction. In a clinical phase 2/3 trial, diacerein has recently been shown to significantly reduce blister numbers upon topical application. In this study we addressed basic pharmacokinetic parameters of locally applied diacerein in vitro and in vivo. Read More

View Article and Full-Text PDF
November 2018

Treatment of Severe Hailey-Hailey Disease With Apremilast.

JAMA Dermatol 2018 12;154(12):1453-1456

Department of Dermatology, Université Nice Côte d'Azur, Centre Hospitalier Universitaire Nice, Nice, France.

Importance: Hailey-Hailey disease (HHD) is a rare, autosomal-dominant acantholytic dermatosis characterized clinically by development of recurrent blisters and erosions in friction areas. Despite progression in our understanding of the molecular genetics of HHD, therapy remains suboptimal and there is no known cure.

Objective: To determine whether the novel phosphodiesterase-4 inhibitor apremilast is effective in the treatment of HHD. Read More

View Article and Full-Text PDF
December 2018

Staphylococcal-scalded skin syndrome: evaluation, diagnosis, and management.

World J Pediatr 2018 04 5;14(2):116-120. Epub 2018 Mar 5.

The Pediatric Institute, Kuala Lumpur General Hospital, Kuala Lumpur, Malaysia.

Background: Staphylococcal-scalded skin syndrome (SSSS), also known as Ritter disease, is a potentially life-threatening disorder and a pediatric emergency. Early diagnosis and treatment is imperative to reduce the morbidity and mortality of this condition. The purpose of this article is to familiarize physicians with the evaluation, diagnosis, and treatment of SSSS. Read More

View Article and Full-Text PDF

Adhesion, Stiffness, and Instability in Atomically Thin MoS Bubbles.

Nano Lett 2017 09 3;17(9):5329-5334. Epub 2017 Aug 3.

Department of Mechanical Engineering, Boston University , Boston, Massachusetts 02215 United States.

We measured the work of separation of single and few-layer MoS membranes from a SiO substrate using a mechanical blister test and found a value of 220 ± 35 mJ/m. Our measurements were also used to determine the 2D Young's modulus (E) of a single MoS layer to be 160 ± 40 N/m. We then studied the delamination mechanics of pressurized MoS bubbles, demonstrating both stable and unstable transitions between the bubbles' laminated and delaminated states as the bubbles were inflated. Read More

View Article and Full-Text PDF
September 2017

Prevention of Friction Blisters in Outdoor Pursuits: A Systematic Review.

Wilderness Environ Med 2017 Jun;28(2):139-149

Department of Emergency Medicine, State University of New York Upstate Medical University, Syracuse, NY (Dr Joslin).

The purpose of this systematic review was to determine if sock, antiperspirant, or barrier strategies were effective in prevention of friction blisters in wilderness and outdoor pursuits. A search of PubMed and EMBASE was conducted. Title, abstract, and full text articles were screened by 2 authors using predetermined inclusion and exclusion criteria to identify prospective controlled trials investigating prevention methods for friction blisters involving the foot. Read More

View Article and Full-Text PDF

Bullous morphoea: a retrospective study.

Clin Exp Dermatol 2017 Jul 22;42(5):532-535. Epub 2017 May 22.

Section of Dermatology, Mario Aresu Department of Medical Science, University of Cagliari, Cagliari, Italy.

Bullous morphoea is a rare variant of localized scleroderma whose pathogenesis has been widely discussed. We retrospectively reviewed the records of all histopathologically confirmed cases of morphoea followed from 2005 to 2015 at the Dermatology Clinic and Pathology Institute of the University of Cagliari, Sardinia, Italy. Among 137 patients with morphoea, 2 cases of the bullous variant were identified, which were successfully treated with methotrexate. Read More

View Article and Full-Text PDF