Search Our Scientific Publications & Authors

Orthop Surg 2021 May 4. Epub 2021 May 4.

Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.

Objective: To compare the clinical efficacy of pararectus and ilioinguinal approach in the treatment of acetabular fractures.

Methods: A retrospective analysis of the clinical data of 60 patients with acetabular fractures treated by the pararectus approach or the ilioinguinal approach from January 2016 to January 2019 was performed to record all data by comparing the length of the surgical incision, the time to expose the fracture and the amount of blood loss during the operation. Patients were routinely followed up at 1, 6 and 12 months postoperatively. Read More

J Orthop Trauma 2021 Apr 30. Epub 2021 Apr 30.

John Hunter Hospital, Newcastle, NSW, Australia University of Newcastle, Newcastle, NSW, Australia.

Objective: To identify and analyse the current evidence for the use of open reduction and internal fixation constructs (ORIF) compared to conventional revision total hip arthroplasty (rTHA) for the management of Vancouver B2 periprosthetic femoral fractures (PFF).

Data Sources: A systematic literature search of the MEDLINE, CINAHL and EMBASE databases was conducted. Prospective and retrospective studies were eligible. Read More

Orthop Surg 2021 May 4. Epub 2021 May 4.

Department of Orthopaedic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.

Objective: To compare the accuracy of combined independent risk factors in assessing the risk of hip fractures in elderly women.

Methods: Ninety elderly females who sustained hip fractures (including femoral neck fractures and intertrochanteric fractures) and 110 female outpatients without a hip fracture were included in our cross-sectional study from 24 November 2017 to 20 May 2019. The age of subjects in the present study was ≥65 years, with the mean age of 78. Read More

Sci Rep 2021 May 3;11(1):9424. Epub 2021 May 3.

Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

Systemic sclerosis (SSc) is recognized as a chronic inflammatory disease and several SSc-associated factors may increase the risk of osteoporosis and its related fractures. To determine the prevalence and predictive factors of osteoporosis in Thai SSc, a cross-sectional study was designed in adult SSc patients at Scleroderma clinic, Khon Kaen University Hospital. The prevalence of osteoporosis with the 95% confidence interval (CI) were determined and the odds ratio (OR) with 95%CI were assessed the clinical association with osteoporosis. Read More

J Arthroplasty 2021 Apr 20. Epub 2021 Apr 20.

Traumaplasty.Melbourne, East Melbourne, Victoria, Australia; Department of Orthopaedics, Royal Melbourne Hospital, Parkville, Victoria, Australia.

Background: Hip hemiarthroplasty is the most common arthroplasty option for fractured neck of femur (FNOF). Revision to total hip arthroplasty (THA) is occasionally required. This study aimed to assess the outcome of hemiarthroplasty revised to THA and to assess the impact of femoral head size, dual mobility (DM), and constrained liners. Read More

BMC Musculoskelet Disord 2021 May 3;22(1):407. Epub 2021 May 3.

Nonprofit Organization (NPO) Nagoya Orthopedic Regional Healthcare Support Center, AI Research Division, Meitohonmachi 2-22-1, Meito-ward, Nagoya, Japan.

Background: Less experienced clinicians sometimes make misdiagnosis of hip fractures. We developed computer-aided diagnosis (CAD) system for hip fractures on plain X-rays using a deep learning model trained on a large dataset. In this study, we examined whether the accuracy of the diagnosis of hip fracture of the residents could be improved by using this system. Read More

Nutr Health 2021 May 4:2601060211011798. Epub 2021 May 4.

Centre for Health Systems and Safety Research, Australian Institute of Health Innovation Faculty of Medicine, Health and Human Sciences, Macquarie University, NSW 2109, Australia.

Background: Data in the Offspring Framingham Osteoporosis Study (FOS) suggested that higher intake of dietary fiber was modestly protective against loss of bone mineral density at the femoral neck in men but not in women.

Aim: To examine the relationship of fiber intake with risk of hip fractures in men.

Methods: We included 367 men from the FOS Original cohort, 1730 men from the FOS Offspring cohort, and 782 men from the Concord Health and Ageing in Men Project (CHAMP) in the analysis. Read More

PLoS One 2021 3;16(5):e0251116. Epub 2021 May 3.

Center for Public Health, National Medical Center, Seoul, South Korea.

Increase in travel time, beyond a critical point, to emergency care may lead to a residential disparity in the outcome of patients with acute conditions. However, few studies have evaluated the evidence of travel time benchmarks in view of the association between travel time and outcome. Thus, this study aimed to establish the optimal hospital access time (OHAT) for emergency care in South Korea. Read More

Arch Orthop Trauma Surg 2021 May 3. Epub 2021 May 3.

Department of Orthopaedic Surgery, Duke University Medical Center, 200 Trent Drive, Durham, NC, 27710, USA.

Introduction: Regional anesthesia (RA) is sometimes used to decrease pain and opioid consumption in distal femur fractures. However, the real-world impact of RA on inpatient opioid consumption and outpatient opioid demand is not well known. The hypothesis of this study is that RA would be associated with decreased inpatient opioid consumption and outpatient opioid demand. Read More

ACS Biomater Sci Eng 2021 May 3. Epub 2021 May 3.

Max-Planck-Institut für Chemische Physik fester Stoffe, Nöthnitzer Str. 40, 01187 Dresden, Germany.

The degradation mechanism of human trabecular bone harvested from the central part of the femoral head of a patient with a fragility fracture of the femoral neck under conditions of senile osteoporosis was investigated by high-resolution electron microscopy. As evidenced by light microscopy, there is a disturbance of bone metabolism leading to severe and irreparable damages to the bone structure. These defects are evoked by osteoclasts and thus podosome activity. Read More

Radiol Artif Intell 2020 Mar 25;2(2):e190023. Epub 2020 Mar 25.

Departments of Orthopaedic Surgery (J.D.K., K.M.H., P.T., E.G.M., E.J.G., M.Z.), Emergency Medicine (B.F.D., K.A.P.), and Radiology and Biomedical Imaging (K.C.M., R.P., J.H.S., A.W., E.O., S.M., V.P.), University of California, San Francisco, 6945 Geary Blvd, San Francisco, CA 94121; and Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, Calif (K.V.C.).

Purpose: To investigate the feasibility of automatic identification and classification of hip fractures using deep learning, which may improve outcomes by reducing diagnostic errors and decreasing time to operation.

Materials And Methods: Hip and pelvic radiographs from 1118 studies were reviewed, and 3026 hips were labeled via bounding boxes and classified as normal, displaced femoral neck fracture, nondisplaced femoral neck fracture, intertrochanteric fracture, previous open reduction and internal fixation, or previous arthroplasty. A deep learning-based object detection model was trained to automate the placement of the bounding boxes. Read More

OTA Int 2021 Mar 11;4(1):e094. Epub 2021 Feb 11.

Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.

Introduction: Civilian ballistic injuries are commonly associated with fracture, vascular injury, and soft tissue trauma. Posttraumatic pseudoaneurysms represent an extremely rare subset of vascular injuries following ballistic fractures.

Case: We present the rare case of a posttraumatic pseudoaneurysm that occurred after retrograde femoral nailing of a ballistic distal femur fracture. Read More

OTA Int 2021 Mar 22;4(1):e087. Epub 2020 Dec 22.

Department of Orthopaedics.

Background: Currently, there are 2 mainstream treatments for displaced femoral neck fracture, including internal fixation and arthroplasty. However, there are still some controversial problems as to which treatment should be primarily chosen.

Methods: The relevant studies comparing arthroplasty with internal fixation were searched in the databases of PubMed, Embase, and Cochrane Library. Read More

OTA Int 2020 Sep 5;3(3):e086. Epub 2020 Aug 5.

Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Purpose: The Surgical Implant Generation Network (SIGN) intramedullary nail was designed for use in resource limited settings which often lack fluoroscopy, specialized fracture tables, and power reaming. A newer design iteration, the SIGN Fin nail, was developed to further simplify retrograde femoral nailing by making proximal interlocking screw placement unnecessary. Instead, the leading end of the Fin nail achieves stability through an interference fit within the proximal femoral canal. Read More

OTA Int 2020 Sep 29;3(3):e083. Epub 2020 Jul 29.

Department of Orthopaedic Surgery, University of Rochester School of Medicine and Dentistry, Rochester, NY.

Objectives: Most patients can tolerate a hemoglobin (Hgb) > 8 g per deciliter. In some cases, however, transfusion will delay physical therapy and hospital discharge. This study aims to review Hgb and transfusion data for a large volume of recent hip fracture patients in order to identify new opportunities for decreasing the length of hospital stay. Read More

OTA Int 2020 Jun 5;3(2):e075. Epub 2020 May 5.

Michigan Medicine, University of Michigan, Ann Arbor, MI.

Objectives: There is no definitive evidence to guide clinicians in their decision-making for implant choice regarding long or short intramedullary nails for unstable fracture patterns. Historically short nails were associated with higher rates of perisprothetic fractures which seem to have improved with newer designs. Long intramedullary nails have higher blood loss and time under anesthesia. Read More

OTA Int 2020 Jun 21;3(2):e066. Epub 2020 May 21.

R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.

Objectives: To conduct a pilot trial for the Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH-2) protocol to assess feasibility of a definitive trial.

Design: Pilot trial.

Setting: Twenty-five clinical sites across North America and Australia were initiated, but enrolment occurred in only 15 North American sites. Read More

OTA Int 2020 Jun 5;3(2):e054. Epub 2020 May 5.

Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA.

Objectives: Evaluate the correlation between aortic stenosis and perioperative mortality in patients following surgical fixation of proximal femur fractures.

Design: Retrospectively reviewed case series.

Setting: Two Academic, Level 1 Trauma Centers. Read More

OTA Int 2020 Mar 3;3(1):e061. Epub 2020 Mar 3.

Institute for Global Orthopaedic Trauma, University of California San Francisco, San Francisco, CA.

Objective: Predict loss to follow-up in prospective clinical investigations of lower extremity fracture surgery.

Design: Secondary analysis of 2 prospective clinical trials.

Setting: National public orthopaedic and neurologic trauma tertiary referral hospital in Dar es Salaam, Tanzania, a low-income country in sub-Saharan Africa. Read More

OTA Int 2019 Dec 14;2(4):e033. Epub 2019 May 14.

University of California Davis Medical Center, Sacramento, CA.

Objective: Arthroplasty is the common treatment for intracapsular femoral neck fractures in the elderly. Recent studies have shown that there may be more overall complications related to uncemented hemiarthroplasty compared to cemented, including more subsidence, intraoperative fractures, and postoperative fractures. Uncemented femoral components rely on a press fit, and the risk of these complications would be expected to increase in patients with unrecognized distal extension of femoral neck fractures. Read More

OTA Int 2019 Dec 20;2(4):e023. Epub 2019 Apr 20.

Royal Liverpool University Hospital, Liverpool, England.

Aim: This is a retrospective review of complex periarticular femoral nonunions where bone loss from comminution at original fracture, subsequent infection or lysis was identified and treated by radical excision, internal fixation, and concurrent femoral lengthening from a different level.

Material And Method: Sixteen patients with a mean age of 41 years were treated. There were 6 infected nonunions. Read More

OTA Int 2019 Sep 9;2(3):e026. Epub 2019 Apr 9.

Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics.

Objectives: To describe the regional distribution of fractures sustained by women and health care system characteristics across 17 low- and middle-income countries (LMICs).

Methods: The INternational ORthopaedic MUlticentre Study in fracture care (INORMUS) is an observational study collecting data on patients in LMICs who sustained a fracture or musculoskeletal injury. As a planned analysis for the INORMUS study, we explored differences in fracture locations and demographics reported among 9878 female patients who sustained a fracture within 17 LMICs in 5 regions (China, Africa, India, Other Asia, and Latin America). Read More

OTA Int 2019 Sep 1;2(3):e024. Epub 2019 Apr 1.

Department of Orthopedics and Rehabilitation, University of Wisconsin, 1685 Highland Avenue, Madison, WI.

Purpose: In developing countries, long bone fractures following trauma are a significant contributor to morbidity, and operating room resources are often limited in these settings. The Surgical Implant Generation Network (SIGN) Fin nail may reduce the challenges of retrograde intramedullary nailing of femoral fractures without fluoroscopy. In contrast to the traditional SIGN nail placed in a retrograde fashion, the Fin nail does not require proximal interlocking screws. Read More

OTA Int 2019 Mar 12;2(1):e016. Epub 2019 Mar 12.

Orthopaedic Research Centre of Australia, Brisbane, Queensland, Australia.

Introduction: Traumatic femoral segmental bone loss is a complex clinical problem, one that often requires extreme solutions. This study examines a new treatment strategy for segmental bone loss using patient-specific 3D printed titanium cages in conjunction with the Masquelet technique.

Methods: The study was composed of a clinical observational case series, and a basic science investigation to evaluate the biological activity of the induced membranes using histology, immunohistochemistry (IHC), and gene expression analysis. Read More

OTA Int 2019 Mar 12;2(1):e014. Epub 2019 Mar 12.

Orthopaedic Surgery, Hennepin County Medical Center, Minneapolis, Minnesota.

Introduction: Open reduction internal fixation (ORIF) is the standard of care for displaced acetabular fractures, but the inability to achieve anatomic reduction, involvement of the posterior wall, articular impaction, and femoral head cartilaginous injury are known to lead to poorer outcomes. Acute total hip arthroplasty (THA) is a reasonable treatment option for older patients with an acetabular fracture and risk factors for a poor outcome, but it is only described in case series. The purpose of this study is to compare outcomes of ORIF and acute THA in middle-aged patients with an acetabular fracture from a single center. Read More

OTA Int 2018 May 16;1(1):e004. Epub 2018 May 16.

Oregon Health and Science University, Sam Jackson Hall, S.W. Sam Jackson Park Road, Portland, OR.

Objectives: Anatomic rotational reduction of diaphyseal femur fractures is essential in restoring limb mechanics. Errors in reproducing anteroposterior (AP) or lateral knee reference radiographs of the contralateral limb could result in inaccuracies during rotational reduction. The objective of this study was to examine whether fluoroscopic rotational variation can be observed with the same degree of precision with AP and lateral distal femur projections. Read More

Front Endocrinol (Lausanne) 2021 15;12:622674. Epub 2021 Apr 15.

Department of Endocrine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.

Background: Osteogenesis imperfecta (OI) type V is a rare form of OI which is often characterized by hyperplastic callus. Misdiagnosis is a possibility due to its rarity and because patients involved are mostly in adolescence, a predisposing age for osteosarcoma. Here, we report this case and aim to improve understanding of patients with OI type V and avoid misdiagnosis. Read More

Front Pharmacol 2021 14;12:588095. Epub 2021 Apr 14.

Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China.

Denosumab, a human monoclonal antibody, acts against the receptor activator of nuclear factor-κB ligand and is a promising antiresorptive agent in patients with osteoporosis. This study aimed to update the efficacy and safety of denosumab vs. placebo in osteoporosis or low bone mineral density (BMD) postmenopausal women. Read More

Rev Bras Ortop (Sao Paulo) 2021 Apr 31;56(2):251-255. Epub 2021 Mar 31.

Hospital Regional do Gama, Brasília, DF, Brasil.

 The present study aims to identify the energy required for synthetic proximal femoral fracture after removal of three implant types: cannulated screws, dynamic hip screws (DHS), and proximal femoral nail (PFN).  Twenty-five synthetic proximal femur bones were used: 10 were kept intact as the control group (CG), 5 were submitted to the placement and removal of 3 cannulated screws in an inverted triangle configuration (CSG), 5 were submitted to the placement and removal of a dynamic compression screw (DHSG), and 5 were submitted to the placement and removal of a proximal femur nail (PFNG). All samples were biomechanically analyzed simulating a fall on the greater trochanter using a servo-hydraulic machine to determine the energy (in Joules [J]) required for fracture. Read More

Endocr Pract 2021 May 26;27(5):408-412. Epub 2021 Feb 26.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel; Maccabitech Institute of Research and Innovation, Maccabi Healthcare Services, Israel.

Objective: To investigate the added value of 1/3 radius (1/3R) for the diagnosis of osteoporosis by spine and hip sites and its correlation with prevalent fractures and predicted fracture risk.

Methods: Fracture Risk Assessment Tool (FRAX) scores for hip and major osteoporotic fractures (MOF) with/without trabecular bone score were considered proxy for fracture risk. The contribution of 1/3R to risk prediction was depicted via linear regression models with FRAX score as the dependent variable-first only with central and then with radius T-score as an additional covariate. Read More