Search Our Scientific Publications & Authors

Geriatrics (Basel) 2018 Oct 10;3(4). Epub 2018 Oct 10.

Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, GL53 7AN, UK.

Patients with suspected hip fractures who require further imaging to confirm or disprove the diagnosis may be admitted to orthopaedic or medical departments. We aim to provide evidence regarding the appropriate admission pathway for such patients. This is a retrospective study of all suspected hip fracture patients receiving second-line imaging between 1 January 2015 to 30 June 2016 in one hospital trust. Read More

Nutrients 2019 Apr 19;11(4). Epub 2019 Apr 19.

Department of Food and Nutrition, Wonkwang University, 460 Iksandaero, Iksan, Jeonbuk 54538, Korea.

Post menopause is considered a critical period for bone-mass loss. Impaired bone metabolism during this phase can increase the risk of fractures in old age. Inflammation is a risk factor for bone health, and diet is a potential source of inflammation. Read More

Ann Intern Med 2019 Apr 23. Epub 2019 Apr 23.

University of Minnesota and Minneapolis VA Health Care System, Minneapolis, Minnesota (H.A.F., R.M., K.E.E., K.U., B.C.T., T.J.W.).

Background: Optimal long-term osteoporosis drug treatment (ODT) is uncertain.

Purpose: To summarize the effects of long-term ODT and ODT discontinuation and holidays.

Data Sources: Electronic bibliographic databases (January 1995 to October 2018) and systematic review bibliographies. Read More

Medicine (Baltimore) 2019 Apr;98(16):e15294

University Children's Hospital Basel (UKBB), Department of Pediatric Surgery, 4056 Basel.

Rationale: Damage control is a staged surgical approach to manage polytraumatized patients. The damage control approach comprises three steps. First, bleeding is controlled and fractures are stabilized temporarily; second, vital parameters are stabilized and the child is rewarmed in the intensive care unit; and third, the child is reoperated for definitive repair of injuries. Read More

J Orthop Trauma 2019 May;33(5):e203-e206

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.

Fractures of the femur have long been a major cause of morbidity and mortality in developing countries and are most frequently caused by road traffic accidents. Intramedullary nail fixation has become the gold standard of care for diaphyseal fractures of the femur. However, modern techniques require proper implants, access to imaging, and accessible operating room facilities, all of which have limited availability in the developing world. Read More

Clin Anat 2019 Apr 22. Epub 2019 Apr 22.

Department of Anatomy and Life Structure, Juntendo University Graduate School of Medicine, Tokyo, Japan.

Introduction: The localization of nutrient foramina and direction of nutrient canals have been studied. However, information about the origin and extraosseous course of nutrient arteries is lacking in some types of long tubular and irregular bones. Thus, we aimed to reexamine the origin and course of the femoral nutrient artery (FNA) through cadaveric dissection to clarify its anatomic characteristics. Read More

Osteoporos Sarcopenia 2019 Mar 15;5(1):6-10. Epub 2019 Mar 15.

University Hospitals of Morecambe Bay NHS Foundation Trust, Royal Lancaster Infirmary, Rheumatology, Ashton Road, Lancaster, Lancashire, UK.

Objectives: Bone mineral density (BMD) and fragility fracture (FF) have high heritability, but few data exist on impact of other factors on families with fracture history. We aimed to evaluate predictors of FF and low BMD, in patients with family history of FF.

Methods: This was a retrospective study on patients undergoing dual energy X-ray absorptiometry at a district general hospital (DGH), 2004-2016. Read More

Pan Afr Med J 2018 2;31:73. Epub 2018 Oct 2.

Service de Chirurgie Orthopédique, CHU Rabat, Hopital Ibn Sina, Université Mohammed V, Souissi, Maroc.

We report a series of seven cases of fractures of the distal end of the femur treated by retrograde centro-medullary nailing in the Orthopedic-Trauma Department at the Hospital Ibn Sina over the period 30/05/2010 - 30/04/2015. The average age of patients was 54 years, with a slight male predominance (57,1%). Road traffic accidents were the main cause of these fractures (71. Read More

Hip Int 2019 Apr 21:1120700019843120. Epub 2019 Apr 21.

1 Academic Orthopaedic Unit, Papageorgiou General Hospital, Aristotle University Medical School, Thessaloniki, Greece.

Introduction: Direct Superior Approach (DSA) is a muscle sparing approach for total hip arthroplasty (THA) implemented using special instrumentation. There is a lack of information in the literature concerning DSA with standard instrumentation.

Materials And Methods: 238 patients were recruited for primary THA by a single surgeon from January 2016 until May 2017. Read More

Calcif Tissue Int 2019 Apr 20. Epub 2019 Apr 20.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Atypical femoral fracture is a well-documented adverse reaction to bisphosphonates. It is strongly related to duration of bisphosphonate use, and the risk declines rapidly after drug withdrawal. The mechanism behind bisphosphonate-associated atypical femoral fracture is unclear, but a genetic predisposition has been suggested. Read More

Bone 2019 Apr 17. Epub 2019 Apr 17.

Department of Radiology, Beijing Jishuitan Hospital, Beijing, China. Electronic address:

The purpose of this study was to investigate the differences in bone mineral density (BMD) and hip structure between femoral neck and trochanteric fractures in elderly Chinese individuals using quantitative computed tomography (QCT). A total of 625 Chinese patients (mean age 75.8 years) who sustained low-energy hip fractures (female: 293 femoral neck, 175 trochanteric; male: 82 femoral neck, 75 trochanteric) were recruited. Read More

Mil Med 2019 Apr 20. Epub 2019 Apr 20.

Mont-Louis Private Hospital, 8 rue de la Folie-Regnault 75011 Paris, France.

Missile injuries of the sciatic nerve are frequently encountered in modern violent conflicts. Gunshot and fragment wounds may cause large nerve defects, for which management is challenging. The great size of the sciatic nerve, in both diameter and length, explains the poor results of nerve repair using autografts or allografts. Read More

Orthop Surg 2019 Apr 19. Epub 2019 Apr 19.

Department of Orthopaedics, Pidu District People's Hospital, Chengdu.

Objective: To compare the clinical efficacy of intramedullary nail fixation for intertrochanteric fractures assisted by orthopaedic robot navigation and the traditional intramedullary nail fixation in elderly patients, and to investigate the application advantages of intramedullary nail fixation for femoral intertrochanteric fractures assisted by orthopaedic robot navigation in the elderly.

Methods: Among the 51 patients with intertrochanteric fractures who were selected from April 2015 to September 2017 in the Affiliated Hospital of Chengdu University, 25 patients underwent the intramedullary nail fixation assisted by orthopaedic robot navigation (orthopaedic robot navigation surgery group) and 26 patients underwent the traditional intramedullary nail fixation (traditional surgery group). The operation time, the number of intraoperative fluoroscopy images taken, the frequency of guide pins inserted into the femoral marrow cavity, the amount of intraoperative bleeding, and the one-time success rate of the guide pin inserted into the femoral marrow cavity were recorded. Read More

J Diabetes Complications 2018 Dec 22. Epub 2018 Dec 22.

Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. Electronic address:

Aim: It is currently unclear if longstanding type 1 diabetes (T1D) affects bone mineral density (BMD).

Methods: BMD measured by dual-energy X-ray absorptiometry and history of fragility fracture was determined in 75 T1D participants with ≥50 years of diabetes duration and 75 age- and sex-matched non-diabetic controls. BMD T-scores were determined for the lumbar spine (LS), total hip (TH) and femoral neck (FN). Read More

Injury 2019 Mar 18. Epub 2019 Mar 18.

Department of Orthopaedics, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, China. Electronic address:

Objectives: The aim of this study was to develop a systematic three-dimensional (3D) classification of intertrochanteric fractures by clustering the morphological features of fracture lines using the Hausdorff distance-based K-means approach and assess the usefulness of it in the clinical setting.

Methods: We retrospectively analyzed the data of 504 patients with intertrochanteric fractures who underwent closed reduction and intramedullary internal fixation. The morphological fracture lines of all patients extracted from computed tomography were transcribed freehand onto the template. Read More

J Med Case Rep 2019 Apr 20;13(1):99. Epub 2019 Apr 20.

Department of Endocrinology and Metabolism, Dokkyo Medical University, Mibu, Shimotsuga, Tochigi, 321-0293, Japan.

Background: Adefovir dipivoxil is a nucleotide analogue that is approved for treatment of chronic hepatitis B. Adefovir dipivoxil is associated with proximal tubular dysfunction, resulting in Fanconi syndrome, which can cause secondary hypophosphatemic osteomalacia. We describe a case of a patient with hypophosphatemic osteomalacia secondary to Fanconi syndrome induced by adefovir dipivoxil concomitantly with osteoporosis in whom clinical symptoms were improved by adding denosumab (a human monoclonal antibody targeting the receptor activator of nuclear factor-κB ligand) to preceding administration of vitamin D. Read More

J Midlife Health 2019 Jan-Mar;10(1):37-42

Medical Research Centre-Kasturba Health Society, Mumbai, Maharashtra, India.

Context: had shown anti-osteoporotic and fracture-healing activities in animal models of postmenopausal osteoporosis (PMO). Standardized extract of leaves of (SEL-Ds) was clinically evaluated for osteoporosis.

Aims: To investigate the anti-osteoporotic activity of in PMO by dual-energy X-ray absorptiometry (DXA), biochemical markers, and effect on clinical profile. Read More

J Arthroplasty 2019 Mar 19. Epub 2019 Mar 19.

Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter Hospital, Exeter, United Kingdom.

Background: Cement-in-cement femoral revision is a proven technique in revision total hip arthroplasty, with excellent results reported using standard-sized Exeter stems. The Exeter 44/00/125 short revision stem was introduced in 2004 to facilitate cement-in-cement revision. The stem is 25-mm shorter and has a slimmer body than standard stems to facilitate adjustment of depth of insertion and stem version. Read More

Exp Gerontol 2019 Apr 16;122:1-9. Epub 2019 Apr 16.

Department of Trauma, Hand and Reconstructive Surgery, Saarland University, 66421 Homburg, Germany; Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg, Germany.

Fracture healing in the elderly is associated with a declined healing potential caused by multiple factors including a delay of vascularization. Erythropoietin (EPO) has been demonstrated to improve vascularization and fracture healing in adult mice. We, therefore, hypothesized that EPO in aged mice also improves fracture healing. Read More

Clin Orthop Relat Res 2019 May;477(5):1176-1187

E. Gallazzi, L. Zagra, IRCCS Istituto Ortopedico Galeazzi, Hip Department, vi R. Galeazzi, Milan, Italy I. Morelli, G. Peretti, Department of Biomedical Sciences for Health, University of Milan, Milan, Italy IRCCS Istituto Ortopedico Galeazzi, via R. Galeazzi Milan, Italy.

Background: Femoral osteotomies have been widely used to treat a wide range of developmental and degenerative hip diseases. For this purpose, different types of proximal femur osteotomies were developed: at the neck as well as at the trochanteric, intertrochanteric, or subtrochanteric levels. Few studies have evaluated the impact of a previous femoral osteotomy on a THA; thus, whether and how a previous femoral osteotomy affects the outcome of THA remains controversial. Read More

J Child Orthop 2019 Apr;13(2):220-225

Children's Hospital New Orleans/LSU Health Sciences Center, New Orleans, Louisiana, USA.

Purpose: Although spica casting remains the benchmark for treating diaphyseal femur fractures in preschool children, some authors advocate using flexible intramedullary nails in certain situations. The aim of the current study was to evaluate the anatomic feasibility of flexible nailing in young children.

Methods: Consecutive patients between the ages of zero and ten years with normal femurs who received femur radiographs at a tertiary paediatric hospital over a two-year period were included. Read More

J Child Orthop 2019 Apr;13(2):213-219

Department of Orthopaedics Division of Pediatric Orthopaedic Surgery, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

Purpose: Tibia fractures are the third most common long bone fracture in children. Because of the remodelling potential of the tibial diaphysis, nonoperative treatment has historically been advocated for most tibial shaft fractures in children. The purpose of this study was to estimate the rate of surgical treatment of tibial shaft fractures over time and identify demographic factors associated with surgical treatment, utilizing a large, publicly available, national database. Read More

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):283-287

Department of Traumatology and Orthopaedics, Peking University People's Hospital, Beijing 100044, China.

Objective: To explore the effect of cephalomedullary nails for elderly intertrochanteric fractures: proximal femoral nail antirotation (PFNA) versus zimmer natural nail (ZNN) to provide the data support for clinical perioperative management.

Methods: A retrospective study was used to analyze the clinical data of elderly intertrochanteric fractures cases which were treated with PFNA or ZNN fixation from May 2016 to May 2017. In the study, 59 cases were followed up completely, in which 28 cases accepted PFNA, and the other 31 cases accepted ZNN. Read More

PLoS One 2019 17;14(4):e0215405. Epub 2019 Apr 17.

Berlin-Brandenburg Center for Regenerative Therapies, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Alterations of structure and density of cortical bone are associated with fragility fractures and can be assessed in vivo in humans at the tibia. Bone remodeling deficits in aging women have been recently linked to an increase in size of cortical pores. In this ex vivo study, we characterized the cortical microarchitecture of 19 tibiae from human donors (aged 69 to 94 years) to address, whether this can reflect impairments of the mechanical competence of the proximal femur, i. Read More

Vet Surg 2019 Apr 16. Epub 2019 Apr 16.

Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.

Objective: To determine the prevalence of surgical site infection (SSI) after internal fixation and to identify risk factors for SSI and nonsurvival.

Study Design: Retrospective study.

Animals: One hundred fifty-five horses with long bone fractures or arthrodesis treated by internal fixation at 1 hospital between 2008-2016. Read More

BMC Musculoskelet Disord 2019 Apr 16;20(1):172. Epub 2019 Apr 16.

Traumatology and Orthopedic Surgery Department, Hospital Universitario Santa Cristina, Calle del Maestro Vives 2 y 3, Madrid, Spain.

Background: Hip resurfacing arthroplasty (HRA) and in particular, Birmingham hip resurfacing (BHR), is commonly employed as an alternative to total hip arthroplasty (THA) in young patients, as it allows for preservation of femoral bone stock and resumption of physical activity. The aim of our study was to investigate 5-year survival and functional outcomes of BHR arthroplasty in young Spanish osteoarthritis (OA) patients.

Methods: This is an observational, prospective, cohort study of patients who underwent BHR between June 2005 and December 2009 at a Spanish public hospital with a minimum follow-up of 5 years. Read More

Orthop Surg 2019 Apr 15. Epub 2019 Apr 15.

Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, China.

Objective: To compare the biomechanical stabilities of less invasive stabilization system (LISS) plate and retrograde intramedullary nail (IMN) for the comminuted femoral supracondylar fracture fractures in the elderly.

Methods: Sixteen pairs of embalmed cadaver femurs were obtained to simulate a comminuted supracondylar femur fracture (AO/OTA33-A3) gap model. All left-side specimens were fixed with LISS plate, and retrograde IMN were applied to the right-side specimens. Read More

Oper Orthop Traumatol 2019 Apr 12. Epub 2019 Apr 12.

Fabricius Klinik, Gelenkzentrum Bergisch Land, Freiheitstsr. 203, 42853, Remscheid, Germany.

Objective: Portal assisted minimally invasive total hip arthroplasty without dislocation of the femoral head with preservation of the hip capsule and the external rotators in the lateral decubitus position for rapid recovery with the option of expandability to a mini posterior or classic posterolateral approach at any time.

Indications: Primary and secondary arthritis of the hip, femoral head necrosis, femoral neck fracture.

Contraindications: Severe anatomical disorders of the proximal femur, congenital high hip dysplasia, implanted hardware in the trochanteric region, local and systemic infections. Read More

Medicine (Baltimore) 2019 Apr;98(15):e15163

Department of Orthopaedics, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China.

We present a safe percutaneous technique for the placement of Kirschner wires into the femoral head to assist in the reduction of irreducible femoral neck fractures using ultrasound to identify the vascular and nervous structures about the hip.From January 2011 to June 2014, a total of 36 patients (25 males and 11 females) were enrolled in this study. Patients were placed on a fracture reduction table for limb traction. Read More

Diabetes Metab Res Rev 2019 Apr 15:e3170. Epub 2019 Apr 15.

NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China.

Aims: To update and determine the effects of sodium glucose co-transporter 2 (SGLT2) inhibitor therapy on fracture and bone mineral density (BMD) in type 2 diabetes mellitus (T2DM) patients.

Materials And Methods: We identified 27 eligible randomized controlled trials (RCTs) that compared the efficacy and safety of SGLT2 inhibitors to a placebo in 20895 T2DM participants, with an average duration of 64.22 weeks. Read More

Injury 2019 Apr 5. Epub 2019 Apr 5.

Medical University of Vienna, Department of Orthopaedics and Trauma Surgery, Waehringer Guertel 18-20, A-1090, Vienna, Austria. Electronic address:

Background: Compartment syndrome of the thigh (CST) is a rare condition, and its delayed diagnosis and therapy may lead to devastating adverse effects. Thus, the aim of this study was to present the amassed clinical experiences, regarding diagnosis and treatment of CST at a level I trauma centre.

Materials And Methods: The database was reviewed for all patients with a manifest CST treated surgically between 1995 and 2014. Read More

Ann Biomed Eng 2019 Apr 12. Epub 2019 Apr 12.

Department of Orthopaedic Surgery, Washington University School of Medicine, 660 S. Euclid, CB 8233, St. Louis, MO, 63110, USA.

Fracture healing is a complex and integrated process that involves mesenchymal progenitor cell (MPC) recruitment, proliferation and differentiation that eventually results in bone regeneration. Prostaglandin E2 (PGE2) is an important regulator of bone metabolism and has an anabolic effect on fracture healing. Prior work from our laboratory showed EP1 mice have enhanced fracture healing, stronger cortical bones, higher trabecular bone volume and increased in vivo bone formation. Read More

Niger J Clin Pract 2019 Apr;22(4):485-491

Orthopaedic Surgery Unit, Imo State University Teaching Hospital, Orlu, Imo State, Nigeria.

Objective: Locked intramedullary nailing is the treatment of choice not only in diaphyseal fractures of long bone but also in most metaphyseal and periarticular fractures. In this study, we set out to present our experience with the Surgical Implant Generation Network (SIGN)] technique of locked intramedullary nailing in long bones that do not require the use of image intensifier, fracture table, and power reamers.

Patients And Methods: This was a hospital-based prospective descriptive study involving 54 consecutive patients seen over a 2-year period. Read More

BMC Vet Res 2019 Apr 11;15(1):114. Epub 2019 Apr 11.

Comparative Biomedical Sciences, Skeletal Biology Group, The Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.

Background: Our understanding of the biology of osteoblasts is important as they underpin bone remodelling, fracture healing and processes such as osseointegration. Osteoblasts isolated from human humeral samples display distinctive biological activity in vitro, which relates to the samples' bone types (subchondral (S), trabecular (T), cortical (C)). Our aim was to isolate primary osteoblast cultures from different bone types from the proximal femur of a clinical population of dogs presented for total hip replacement and compare the behaviour of the osteoblasts derived from different bone types, to identify a preferred bone type for isolation. Read More

Pediatr Emerg Care 2019 Apr 9. Epub 2019 Apr 9.

Saint Louis School of Medicine, St. Louis.

Objective: Screening blood work after minor injuries is common in pediatric trauma. The risk of missed injuries versus diagnostic necessity in an asymptomatic patient remains an ongoing debate. We evaluated the clinical utility of screening blood work in carefully selected asymptomatic children after minor trauma. Read More

Skeletal Radiol 2019 Apr 10. Epub 2019 Apr 10.

Faculty of Medicine, Department of Orthopaedics and Traumatology, Mugla Sitki Kocman University, 48000, Mentese, Mugla, Turkey.

Objective: The aim of this study was to evaluate the sensitivity and specificity of radiographs in identifying incomplete atypical femoral fractures and to determine interobserver and intra-observer reliability.

Materials And Methods: Anterior-posterior and lateral radiographs of 10 femurs with incomplete atypical femoral fractures confirmed using bone scintigraphy and magnetic resonance imaging, and 40 femurs without incomplete atypical femoral fractures confirmed using bone scintigraphy, were reviewed by 4 orthopedic surgeons and 4 radiology specialists. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive value were calculated to determine a diagnosis of incomplete atypical femoral fractures. Read More

Biomed Pharmacother 2019 Apr 2;112:108658. Epub 2019 Mar 2.

The First Affiliated Hospital of Guangdong University of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China. Electronic address:

Objective: To compare the bifomechanical advantages and disadvantages of different internal fixation methods for the treatment of Pauwels type III femoral neck fractures.

Methods: 4 internal fixations were developed to treat Pauwels type III femoral neck fracture finite element models: a: the "F" shaped cannulated screw model, b: the traditional cannulated screw model, c: the "F" shaped cannulated screw coupled with medial plate model, d: the traditional cannulated screw coupled with medial plate. Under the same conditions, the 4 internal fixations and femur of von Mises stress and displacement distribution were studied. Read More

J Am Acad Orthop Surg 2019 Apr 8. Epub 2019 Apr 8.

From the Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT (Dr. Schneble), the Department of Orthopaedic Surgery (Dr. Natoli), the Department of Radiology (Dr. Schonlau), the Department of Surgery (Dr. Reed), Indiana University School of Medicine, Indianapolis, IN, and the Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, NC (Dr. Kempton).

Introduction: The Centers for Medicare & Medicaid services proposed that transitioning from the 9th to the 10th revision of the International Classification of Disease (ICD) would provide better data for research. This study sought to determine the reliability of ICD-10 compared with ICD-9 for proximal femur fractures.

Methods: Available imaging studies from 196 consecutively treated proximal femur fractures were retrospectively reviewed and assigned ICD codes by three physicians. Read More

Knee Surg Sports Traumatol Arthrosc 2019 Apr 9. Epub 2019 Apr 9.

Department of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland.

Purpose: There is a lack of knowledge about the native coronal knee alignment in 3D. The currently used classification system (neutral, valgus and varus) oversimplifies the coronal knee alignment. The purpose of this study was therefore (1) to investigate the coronal knee alignment in non-osteoarthritic knees using 3D-reconstructed CT images and (2) to introduce a classification system for the overall knee alignment based on phenotypes. Read More

Int Orthop 2019 Apr 9. Epub 2019 Apr 9.

Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Background: Cementless hemiarthroplasty is a widely used treatment for femoral neck fractures. Intra-operative femoral fracture occasionally occurs during the procedure, and the use of cerclage wire has been proposed to stabilize both the prosthesis and the bone. This study aimed to investigate the outcomes of cerclage wiring to manage intra-operative fractures occurring during cementless hemiarthroplasty in older patients with a femoral neck fracture. Read More

Front Physiol 2019 25;10:236. Epub 2019 Mar 25.

Department of Orthopaedic Trauma Surgery, RWTH Aachen University Hospital, Aachen, Germany.

Proximal femur fractures represent a major healthcare problem in the aging society. High rates of post-operative infections are linked to risk factors that seem to affect local microcirculation. Patterns and time courses of alterations in microcirculation have, however, not been previously investigated. Read More

Indian J Orthop 2019 Mar-Apr;53(2):246-250

Department of Orthopaedics Surgery, Changhua Christian Hospital, Changhua, Taiwan.

Background: The treatment of subtrochanteric fracture nonunion is challenging. Although revision with either an intramedullary or extramedullary device had been advocated with acceptable results, complications that require secondary procedures still arise. The use of an intramedullary device with augmentation plate fixation is a well-known approach for femoral or tibial diaphyseal nonunion. Read More

Indian J Orthop 2019 Mar-Apr;53(2):232-236

Department of Trauma and Orthopaedics, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.

Background: The number of elderly patients sustaining long bone fractures is increasing with the rise of elderly population in the western world. Management of distal femur fractures is particularly difficult due to osteoporosis and other associated comorbidities. The key to management would be by surgical stabilization, which allows early mobilization. Read More

Acta Biomater 2019 Apr 6. Epub 2019 Apr 6.

Department of Biomedical Engineering, Lund University, Lund, Sweden; Department of Orthopaedics, Clinical Sciences, Lund University, Lund, Sweden. Electronic address:

Positron emission tomography (PET) is a form of nuclear imaging, which quantitatively assesses the metabolic activity through the uptake of radioactive tracers. F-fluoride is a positron-emitting isotope with high affinity for bone. Despite its potential as a non-invasive measure of bone metabolism, quantitative F-fluoride PET has only been used sparsely in orthopaedic applications. Read More

J Am Podiatr Med Assoc 2019 Jan;109(1):13-21

Background: We sought to investigate the different configurations of Kirschner wires used in distal femur Salter-Harris (SH) type 2 epiphyseal fracture for stabilization after reduction under axial, rotational, and bending forces and to define the biomechanical effects on the epiphyseal plate and the fracture line and decide which was more advantageous.

Methods: The SH type 2 fracture was modeled using design software for four different configurations: cross, cross-parallel, parallel medial, and parallel lateral with two Kirschner wires, and computer-aided numerical analyses of the different configurations after reduction were performed using the finite element method. For each configuration, the mesh process, loading condition (axial, bending, and rotational), boundary conditions, and material models were applied in finite element software, and growth cartilage and von Mises stress values occurring around the Kirschner wire groove were calculated. Read More

Endocrine 2019 Apr 8. Epub 2019 Apr 8.

Endocrinology and Nutrition Unit, Hospital Universitario San Cecilio de Granada, Department of Medicine, University of Granada, Granada, Spain.

Several antiresorptive drugs, like bisphosphonates and denosumab, are currently available for the treatment of osteoporosis due to their evidenced efficacy in reducing fracture risk at mid-term. Osteoanabolic therapies, like teriparatide, whose treatment duration is limited to 2 years, have also shown efficacy in the reduction of fracture risk. However, depending on the severity of osteoporosis and the presence of other associated risk factors for fracture, some patients may require long-term treatment to preserve optimal bone strength and minimize bone fracture risk. Read More

J Knee Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Orthopaedic Surgery, Hennepin Healthcare, Minneapolis, Minnesota.

Periprosthetic fractures around total knee arthroplasty have become more common with the increasing incidence of total knee arthroplasty. These fractures are challenging to treat, especially in older patients with poor bone stock. Although open reduction internal fixation remains the most common treatment, revision with distal femoral replacement has become popular in recent years. Read More

J Am Acad Orthop Surg 2019 Apr;27(8):e346-e355

From the Department of Orthopaedics, University of Utah, Salt Lake City, UT.

Fat embolism (FE) occurs frequently after trauma and during orthopaedic procedures involving manipulation of intramedullary contents. Classically characterized as a triad of pulmonary distress, neurologic symptoms, and petechial rash, the clinical entity of FE syndrome is much less common. Both mechanical and biochemical pathophysiologic theories have been proposed with contributions of vascular obstruction and the inflammatory response to embolized fat and trauma. Read More

J Arthroplasty 2019 Mar 19. Epub 2019 Mar 19.

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.

Background: The collum femoris preserving (CFP) stem was a specially designed femoral neck preserving component. The incidence, classification, and risk factors for intraoperative periprosthetic femoral fractures with this special stem remain unclear.

Methods: This was a retrospective study. Read More