61,357 results match your criteria Fracture Femur

A clinical and biomechanical comparison of INFIX plus single versus double sacroiliac screw fixation for unstable pelvic ring injury.

J Orthop Surg Res 2022 May 21;17(1):285. Epub 2022 May 21.

Department of Orthopaedics, The Fifth Affiliated Hospital, Southern Medical University, No. 566 Congcheng Avenue, Conghua District, Guangzhou, 510900, People's Republic of China.

Background: The aim of this study is to compare the clinical and biomechanical outcome of INFIX plus single with two sacroiliac screw fixation for unstable pelvic fractures of Type C.

Methods: Sixteen cadavers were randomly subjected to INFIX plus single or double sacroiliac screw fixations and then mounted onto the ElectroForce loading machine under different vertical loads. To investigate the clinical outcomes of the two techniques, nineteen patients were retrospectively analyzed. Read More

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Association of bone-related biomarkers with femoral neck bone strength.

BMC Musculoskelet Disord 2022 May 21;23(1):482. Epub 2022 May 21.

Department of Orthopedics, The General Hospital of Western Theater Command, Rongdu Avenue No. 270, Chengdu, 610083, China.

Background: Femoral neck fractures are the worst consequence of osteoporosis (OP), and its early prevention and treatment have become a public health problem. This study aims to investigate the relationship of bone-related biomarkers, femoral neck bone mineral density (BMD) and maximum load (L), selecting the indicator which can reflect femoral neck bone loss and reduced bone strength.

Methods: A total of 108 patients were recruited from January 2017 to December 2019. Read More

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Calcimimetics Alter Periosteal and Perilacunar Bone Matrix Composition and Material Properties in Early Chronic Kidney Disease.

J Bone Miner Res 2022 May 20. Epub 2022 May 20.

Indiana University-Purdue University at Indianapolis, Department of Biomedical Engineering, Indianapolis, IN.

Chronic kidney disease (CKD) affects 15% of Americans and greatly increases fracture risk due to elevated parathyroid hormone, cortical porosity, and reduced bone material quality. Calcimimetic drugs are used to lower PTH in CKD patients, but their impact on bone matrix properties remains unknown. We hypothesized that tissue-level bone quality is altered in early CKD and that calcimimetic treatment will prevent these alterations. Read More

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The effect of age and initial compression on the force relaxation response of the femur in elderly women.

Saulo Martelli

R Soc Open Sci 2022 May 4;9(5):220301. Epub 2022 May 4.

Centre for Biomedical Technologies, School of Mechanical, Medical and Process Engineering, Queensland University of Technology (QUT), Brisbane, Australia.

The effect of force amount, age, body weight and bone mineral density (BMD) on the femur's force relaxation response was analysed for 12 donors (age: 56-91 years). BMD and fracture load, , were estimated from clinical CT images. The 30 min force relaxation was obtained using a constant compression generating an initial force between 7% and 78% of . Read More

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Improvement of survival after 10 years with the Durom-type hip resurfacing prosthesis in selected patients: Experience of a public university hospital.

Rev Esp Cir Ortop Traumatol 2022 May-Jun;66(3):182-188. Epub 2021 Nov 23.

Unidad de Cadera, Parc de Salut Mar, Universidad Autónoma de Barcelona, Barcelona, España.

Introduction: Hip resurfacing arthroplastys are a valid alternative for the treatment of degenerative hip disorders in young adults. Poor results and adverse soft tissue effects have been reported with high levels of chromium and cobalt, limiting its indications. Objective is to analyze clinical and functional survival results of the Durom system 10 years after its implementation in a public hospital. Read More

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November 2021

Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine?

BMC Musculoskelet Disord 2022 May 19;23(1):469. Epub 2022 May 19.

Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy.

Background: Osteoarthritis (OA) and vertebral fractures at the lumbar spine lead to an overestimation of bone mineral density (BMD). Recently, a new approach for osteoporosis diagnosis, defined as radiofrequency echographic multi-spectrometry (REMS), represents an innovative diagnostic tool that seems to be able to investigate bone quality and provide an estimation of fracture risk independent of BMD. The aim of this paper was to evaluate whether the use of REMS technology can favor the diagnosis of osteoporosis in subjects with an apparent increase in BMD. Read More

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Risk factors of fracture following curettage for bone giant cell tumors of the extremities.

BMC Musculoskelet Disord 2022 May 19;23(1):477. Epub 2022 May 19.

Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy.

Background: Following curettage of giant cell tumor of bone (GCTB), it is common to fill the cavity with polymethylmethacrylate (PMMA) bone cement, bone allograft, or artificial bone to maintain bone strength; however, there is a 2-14% risk of postoperative fractures. We conducted this retrospective study to clarify the risk factors for fractures after curettage for GCTB of the extremities.

Methods: This study included 284 patients with GCTBs of the extremities who underwent curettage at our institutions between 1980 and 2018 after excluding patients whose cavities were not filled with anything or who had additional plate fixation. Read More

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Letter regarding "Nakanishi et al. Ideal screw positions for multiple screw fixation in femoral neck fractures -study of proximal femur morphology in a Japanese population".

J Orthop Sci 2022 May 16. Epub 2022 May 16.

Department of Orthopaedics, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, PR China. Electronic address:

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Mortality and functional consequences after revision osteosynthesis for peritrochanteric fractures treated by intramedullary nail: A retrospective study of 312 patients.

Orthop Traumatol Surg Res 2022 May 16:103325. Epub 2022 May 16.

CH Dunkerque, Service Orthopédie et Traumatologie, 59240 Dunkerque, France.

Introduction: Osteosynthesis of peritrochanteric fractures by intramedullary nail is associated with a 3 to 15% rate of complications requiring revision surgery. The objective of our study was to compare mortality and autonomy between patients who required revision surgery after osteosynthesis, and patients without revision surgery.

Hypotheses: Patients who underwent revision surgery after osteosynthesis of a peritrochanteric fracture by intramedullary nail did not exhibit excess mortality or loss of autonomy compared to those who did not undergo revision surgery. Read More

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Micro-Computed Tomography Analysis of Femoral Head Necrosis After Long-Term Internal Fixation for Femoral Neck Fracture.

Orthop Surg 2022 May 19. Epub 2022 May 19.

Department of Orthopaedics, Second Hospital of Shanxi Medical University, Taiyuan, China.

Objective: To analyze necrotic femoral head after long-term internal fixation for femoral neck fractures using micro-computed tomography (CT) for bone histomorphometry.

Methods: The experimental group included six patients (two men and four women; mean age 62.00 ± 9. Read More

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Is the Rate of Change in Posterior Pelvic Tilt After Total Hip Arthroplasty Constant?

Arthroplast Today 2022 Jun 10;15:147-152. Epub 2022 May 10.

Department of Orthopaedic Surgery, Toyama Prefectural Central Hospital, Toyama, Japan.

Background: The purpose of this study was to evaluate the age-related change in pelvic sagittal inclination in the standing position after total hip arthroplasty (THA). This study hypothesized that the rate of progression of posterior tilt is not constant.

Material And Methods: We measured sacral slope and pelvic tilt in 36 patients who were followed up for more than 10 years after unilateral primary THA. Read More

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Novel Insight into the Relationship Between Muscle-Fat and Bone in Type 2 Diabetes Ranging from Normal Weight to Obesity.

Diabetes Metab Syndr Obes 2022 10;15:1473-1484. Epub 2022 May 10.

Department of Endocrinology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.

Objective: Decreased bone mineral density (BMD) is a common complication in individuals with type 2 diabetes mellitus (T2DM). Body weight, mainly consisting of muscle and fat, is the main determinant of BMD and fracture risks but does not accurately describe nutritional status. Most studies suggest that skeletal muscle mass (SMM) promotes BMD, while body fat mass (BFM) decreases BMD. Read More

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Calculation and application of a safe range of load on the limb in patients after osteosynthesis of the femoral neck.

J Orthop 2022 May-Jun;31:140-144. Epub 2022 May 2.

The Department of Hospital Surgery with the Course of Traumatology, FSBEI HO «Tambov State University named after G.R. Derzhavin», Medical Institute, Kotovsk City Clinical Hospital. Tambov Region, Tambov, Russian Federation.

Background: Fractures of the femoral neck occupy a leading place in the total injury rate in the Russian Federation. Despite significant advances in the field of osteosynthesis of femoral neck fractures, there is still a high percentage of unsatisfactory treatment outcomes, including the cases when functional load is applied in the early activation of patients. Therefore, it is very important to find ways to dose the load on the operated limb in the postoperative period in patients with fractures of the femoral neck. Read More

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Multiple cannulated screw fixation of femoral neck fractures with comminution in young- and middle-aged patients.

J Orthop Surg Res 2022 May 18;17(1):280. Epub 2022 May 18.

Department of Hip Trauma, Tianjin Hospital, No. 406 Jiefang South Road, Hexi District, Tianjin, 300211, China.

Objective: To investigate the distribution and influence of comminution in femoral neck fracture (FNF) patients after cannulated screw fixation (CSF).

Methods: From January 2019 to June 2020, a total of 473 patients aged 23-65 years with FNF treated by CSF were included in the present study. Based on location of the cortical comminution, FNF patients were assigned to two groups: the comminution group (anterior comminution, posterior comminution, superior comminution, inferior comminution, multiple comminutions) or the without comminution group. Read More

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An inconvenient status in anti-osteoporotic treatment process: corticosteroid use.

Rev Assoc Med Bras (1992) 2022 May;68(5):636-640

Gaziantep University, Faculty of Medicine, Department of Internal Medicine, Division of Geriatric Medicine - Gaziantep, Turkey.

Objective: There are limited studies investigating the comparison of the efficacy of anti-osteoporotic drugs in different conditions resulting in osteoporosis in older adults. This study aimed to compare the effectiveness of anti-osteoporotic agents in older adults with or without glucocorticoid-induced osteoporosis.

Methods: This retrospective study included 364 patients with osteoporosis, aged 65 years and older. Read More

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Valproic Acid During Hypotensive Resuscitation In Pigs With Trauma And Hemorrhagic Shock Does Not Improve Survival.

J Trauma Acute Care Surg 2022 May 21. Epub 2022 May 21.

U.S. Army Institute of Surgical Research, JBSA - Fort Sam Houston, TX 78234.

Background: Valproic acid (VPA) has been extensively used for treatment of anxiety and seizure. Recent studies have shown that VPA has cellular protective effects in preclinical models following severe hemorrhage. This study investigated the effects of VPA on coagulation and survival in pigs after traumatic hemorrhage and hypotensive resuscitation. Read More

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Sex-Based Disparities in Timeliness of Trauma Care and Discharge Disposition.

JAMA Surg 2022 May 18. Epub 2022 May 18.

Surgical Outcomes Quality Improvement Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Importance: Differences in time to diagnostic and therapeutic measures can contribute to disparities in outcomes. However, whether there is an association of timeliness by sex for trauma patients is unknown.

Objective: To investigate whether sex-based differences in time to definitive interventions exist for trauma patients in the US and whether these differences are associated with outcomes. Read More

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A Novel Fluoroscopic View for Improved Assessment of the Safety of the Posterosuperior Screw in Femoral Neck Fracture Fixation.

J Bone Joint Surg Am 2022 05 15;104(10):889-895. Epub 2022 Feb 15.

Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.

Background: The purpose of the present study was to determine specific fluoroscopic views of the femoral neck to accurately identify partially extraosseous ("in-out-in"; IOI) placement of the posterosuperior screw for fixation of femoral neck fractures.

Methods: A 3.2-mm guide pin was placed in the posterosuperior aspect of 2 synthetic femur models: 1 entirely intraosseous and 1 IOI. Read More

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Direct anterior approach hip arthroplasty: How to reduce complications - A 10-years single center experience and literature review.

World J Orthop 2022 Apr 18;13(4):388-399. Epub 2022 Apr 18.

Department of Orthopedic Trauma, SS Annunziata Hospital, Savigliano 12038, Italy.

Background: The direct anterior approach for total hip arthroplasty (DAA-THA) is increasing in popularity due to some advantages such as less surgical trauma, minimal dissection of soft tissues, shorter rehabilitation times, faster return to daily activities, lower incidence of dislocation. On the other hand, the literature reports a high rate of intraoperative complications, with many different rates and complication types in the published papers.

Aim: To analyze our complications comparing results with the literature; to report measures that we have taken to reduce complications rate. Read More

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Conversion hip arthroplasty via the direct anterior approach: pearls, pitfalls and personal experience.

Oper Orthop Traumatol 2022 May 17. Epub 2022 May 17.

Department of Orthopaedic and Trauma Surgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

Objective: Conversion total hip arthroplasty (CTHA) through a direct anterior approach (DAA) in supine position.

Indications: Failed osteosynthesis of proximal femoral fractures or failed conservative hip surgery, with hardware in situ.

Contraindications: Decayed general conditions, infection (peri-implant or systemic infection), need for greater trochanter reconstruction, severe proximal femur deformity. Read More

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A murine model of large-scale bone regeneration reveals a selective requirement for Sonic Hedgehog.

NPJ Regen Med 2022 May 17;7(1):30. Epub 2022 May 17.

Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, 1425 San Pablo Street, Los Angeles, CA, 90089, USA.

Building and maintaining skeletal tissue requires the activity of skeletal stem and progenitor cells (SSPCs). Following injury, local pools of these SSPCs become active and coordinate to build new cartilage and bone tissues. While recent studies have identified specific markers for these SSPCs, how they become activated in different injury contexts is not well-understood. Read More

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Primary fibular grafting combined with double plating in distal femur fractures in elderly patients.

Int Orthop 2022 May 17. Epub 2022 May 17.

Department of Orthopedic Surgery, Faculty of Medicine, Ain Shams University, 38 Abbassia Square, Next to Al-Nour Mosque, Cairo, Egypt.

Purpose: To report functional and radiological outcomes of using primary fibular graft together with double plating in distal femoral fractures in the elderly.

Methods: A retrospective study on 30 elderly patients with comminuted distal femoral fractures managed by primary fibular grafting and double plating through an anterior midline approach has been conducted. Only isolated distal femoral fractures type 33-A3, 33-C2, and 33-C3 were included. Read More

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Low geriatric nutritional risk index is a risk factor for death within 1 year following hip fracture.

J Orthop Surg (Hong Kong) 2022 May-Aug;30(2):10225536221103360

Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, 208512Kagoshima University, Kagoshima, Japan.

Purpose: Hip fracture is common in older patients and is associated with high mortality and functional impairment. The Geriatric Nutritional Risk Index (GNRI) evaluates the risk of malnutrition-related complications, and the Barthel Index (BI) evaluates older patients' functional status. The study aim was to determine the risk factors for both death and decreased BI within 1 year after hip fracture. Read More

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Safety of surgical hip dislocation in femoral head fracture and dislocation (FHFD) and avascular necrosis risk factor analysis of FHFD: midterm results confirmed by SPECT/CT and MRI.

J Orthop Surg Res 2022 May 16;17(1):278. Epub 2022 May 16.

Department of Orthopedic Surgery, Ajou University School of Medicine, Yeongtong-gu, Suwon-si, Gyeonggi-do, Republic of Korea.

Background: The study aim was to report the treatment outcomes of trochanteric flip osteotomy (TFO) with surgical hip dislocation (SHD) for femoral head fracture and dislocation (FHFD) and to investigate the risk factors for avascular necrosis (AVN) of the femoral head.

Methods: The data of 34 patients (29 men, 5 women; mean age 37.9 years) diagnosed with FHFD and treated with TFO with SHD between May 2009 and February 2018 with an average follow-up period of 5. Read More

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Cementless bipolar hemiarthroplasty compared with proximal femoral nail anti-rotation of unstable intertrochanteric fractures in senile patients with osteoporosis: a retrospective study.

BMC Musculoskelet Disord 2022 May 16;23(1):461. Epub 2022 May 16.

Department of Orthopedics, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, 712000, Shaanxi, China.

Background: Implant design for the correction of osteoporotic unstable intertrochanteric fractures in elderly patients is a controversial issue. Our study aims to compare the efficacy of PFNA and cementless bipolar hemiarthroplasty (CBH) in treating osteoporotic unstable intertrochanteric fractures in the elderly.

Methods: We retrospectively assessed 70 elderly patients, aged > 70 years old, with intertrochanteric fractures (AO/OTA 31-A2 fractures) from 2014 to 2019. Read More

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Fracture definitions in observational osteoporosis drug effects studies that leverage healthcare administrative (claims) data: a scoping review.

Osteoporos Int 2022 May 17. Epub 2022 May 17.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

Healthcare administrative (claims) data are commonly utilized to estimate drug effects. We identified considerable heterogeneity in fracture outcome definitions in a scoping review of 57 studies that estimated osteoporosis drug effects on fracture risk. Better understanding of the impact of different fracture definitions on study results is needed. Read More

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Risk factors for lower bone mineral density in older adults with type 1 diabetes: a cross-sectional study.

Lancet Diabetes Endocrinol 2022 May 13. Epub 2022 May 13.

Case Western Reserve University/Rainbow Babies and Children's Hospital, Cleveland, OH, USA.

Background: Type 1 diabetes is associated with lower bone mineral density (BMD) and increased fracture risk, but little is known regarding the effects of diabetes-related factors on BMD. We assessed whether these factors are associated with lower hip BMD among older adults with type 1 diabetes.

Methods: This cross-sectional study was embedded in a long-term observational study, the Epidemiology of Diabetes Interventions and Complications study (EDIC), a cohort of participants with type 1 diabetes, who were originally enrolled in the Diabetes Control and Complications Trial (DCCT), and were followed-up for more than 30 years at 27 sites in the USA and Canada. Read More

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Risk of Peri-implant Fracture With Long Versus Short Cephalomedullary Nailing for Geriatric Patients With Intertrochanteric Femur Fracture.

Orthopedics 2022 May 17:1-6. Epub 2022 May 17.

Intramedullary fixation using a short or long cephalomedullary nail (CMN) for treating hip fractures has gained popularity in recent years. We evaluated reoperation rates requiring device removal of short or long CMNs for patients 65 years and older. A retrospective study was performed at a level I trauma center over a 10-year period (2005-2015). Read More

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Associations of Smoking With Delirium and Opioid Use in Older Adults With Traumatic Hip Fracture.

J Am Acad Orthop Surg Glob Res Rev 2022 May 1;6(5). Epub 2022 May 1.

From the Trauma Research Department, Penrose Hospital, Colorado Springs, CO (Salottolo, Dr. Meinig, Kelly, Dr. Tanne II, and Dr. Bar-Or); the Trauma Research Department, St Anthony Hospital, Lakewood, CO (Salottolo, Dr. Madayag, and Dr. Bar-Or); the Trauma Research Department, Wesley Medical Center, Wichita, KS (Salottolo, Dr. Ekengren, and Dr. Bar-Or); the Trauma Research Department, St. Francis Medical Center, Colorado Springs, CO (Dr. Meinig); and the Trauma Research Department, Parker Adventist Hospital, Parker, CO (Dr. Fine).

Introduction: Cigarette smoking is a risk factor for hip fractures, while risk factors for developing delirium include older age and preexisting cognitive impairment. We sought to determine whether smoking status is independently associated with delirium and pain outcomes.

Methods: This was a prospective, observational cohort study of 442 older adults (65 to 90 years) admitted for traumatic hip fracture at five trauma centers. Read More

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