10,564 results match your criteria Fracture Cervical Spine


Night shift work and osteoporosis among female blue-collar workers in Poland - a pilot study.

Chronobiol Int 2020 May 26:1-11. Epub 2020 May 26.

Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine , Lodz, Poland.

Osteoporosis is an important public health problem worldwide. Although a number of factors that affect bone structure have been described; thus far, the current knowledge of occupational factors that may have an influence on bone tissue metabolism is strongly limited. Published studies indicate night shift work and the related circadian rhythm disruption may be considered as plausible underlying factors. Read More

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http://dx.doi.org/10.1080/07420528.2020.1763381DOI Listing

Osteoporosis epidemiology using international cohorts.

Curr Opin Rheumatol 2020 Jul;32(4):387-393

Nuffield Department of Orthopaedics, Centre for Statistics in Medicine , Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Purpose Of Review: The field of osteoporosis research has been active for the past 20 years and has allowed significant advancement in the management of osteoporosis. This review will give an overview of the latest data from international cohorts that relate to current and recent osteoporosis research.

Recent Findings: The clinical diagnosis of osteoporosis relies heavily on bone mineral density (BMD) measured at femoral neck or spine and although BMD has excellent predictive value for future fractures, fracture risk assessment has evolved over the years, resulting in the birth of fracture prediction tools. Read More

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http://dx.doi.org/10.1097/BOR.0000000000000722DOI Listing

Bone turnover markers as an aid to monitor osteoporosis following allogeneic hematopoietic stem cell transplantation.

Ann Hematol 2020 May 25. Epub 2020 May 25.

Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Bunkyo-ku, Tokyo, 113-0021, Japan.

Bone turnover markers (BTMs) are useful parameters for assessing fracture risk and unlike bone mineral density (BMD), can be measured at any institution. However, BTM values have not been established in patients post-allogeneic hematopoietic stem cell transplantation (allo-HSCT). We investigated the practicality of BTMs in patients who underwent allo-HSCT by measuring levels of the serum bone resorption marker, tartrate-resistant acid phosphatase-5b (TRACP-5b), and the bone formation marker, bone-specific alkaline phosphatase (BAP), together with BMD, 1 month before and 6 months after allo-HSCT. Read More

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http://dx.doi.org/10.1007/s00277-020-04090-7DOI Listing

Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.

Biol Trace Elem Res 2020 May 25. Epub 2020 May 25.

Institute of Health Sciences, Interdisciplinary Food, Metabolism and Clinical Nutrition Department, Ankara University, Ankara, Turkey.

Bone-related diseases are very common problems, especially in the elderly population. Zinc takes part in the growth and maintenance of healthy bones. This meta-analysis aims to evaluate the effects of zinc supplementation or dietary zinc intake on serum zinc levels and bone turnover markers. Read More

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http://dx.doi.org/10.1007/s12011-020-02193-wDOI Listing
May 2020
1.748 Impact Factor

Injuries of the upper cervical spine-how can instability be identified?

Int Orthop 2020 May 25. Epub 2020 May 25.

Department of Trauma Surgery and Orthopaedics, BG Trauma Center Ludwigshafen, Ludwig-Guttmann-Str. 13, 67071, Ludwigshafen, Germany.

Objective: The diagnosis of instability of the injured upper cervical spine remains controversial, due to its complicated anatomical configuration and biomechanical property. Since identifying unstable injuries of the upper cervical spine is essential for immediate stabilizing therapy, this article reviews the current classification systems of upper cervical spine injuries and their statements towards instability.

Methods: A systematic review of literature concerning upper cervical spine injuries was performed on the PubMed database from inception to December 2019. Read More

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http://dx.doi.org/10.1007/s00264-020-04593-yDOI Listing

[Skull and cervical spine fractures].

Radiologe 2020 May 25. Epub 2020 May 25.

Klinik für Neurochirurgie, Universitätsmedizin Rostock, Rostock, Deutschland.

Background: Injuries of the skull and the cervical spine are common trauma sequelae and prompt diagnosis is of utmost importance to prevent neurologic complications.

Objectives: The different imaging modalities for the diagnosis of skull and cervical spine fractures are presented and discussed in the context of the current literature.

Materials And Methods: Common fractures of the skull and cervical spine and their classification systems are described. Read More

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http://dx.doi.org/10.1007/s00117-020-00702-5DOI Listing

Prevalence of asymptomatic radiographic vertebral fracture in postmenopausal Thai women.

Arch Osteoporos 2020 May 24;15(1):78. Epub 2020 May 24.

Menopausal Research Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

We aim to investigate the nationwide prevalence of asymptomatic radiographic vertebral fracture in Thailand. We found 29% of postmenopausal women had at least one radiographic vertebral fracture. The prevalence was significantly higher among women with osteoporosis at the total hip (TH) region which implies that TH bone mineral density is a determinant of vertebral fracture risk. Read More

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http://dx.doi.org/10.1007/s11657-020-00762-zDOI Listing

Analysis of the tumor necrosis factor superfamily member 11 gene polymorphism with bone mineral density and bone fracture frequency in patients with postmenopausal osteoporosis.

Adv Med Sci 2020 May 20;65(2):291-297. Epub 2020 May 20.

Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.

Purpose: We aimed to examine the polymorphism of the promoter and exon 5 of the TNFSF11 gene and their impact on bone mineral density (BMD) and the frequency of bone fractures. TNFSF11 encodes the receptor activator of the NF-kB ligand (RANKL), a key regulator of bone metabolism and osteoporosis drug targets. BMD is an essential measure in diagnosing osteoporosis and assessing the risk of fractures. Read More

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http://dx.doi.org/10.1016/j.advms.2020.05.001DOI Listing

T-Score as an Indicator of Fracture Risk During Treatment With Romosozumab or Alendronate in the ARCH Trial.

J Bone Miner Res 2020 May 22. Epub 2020 May 22.

Service and Laboratory of Bone Diseases, Geneva University Hospital, Geneva, Switzerland.

In the Active-Controlled Fracture Study in Postmenopausal Women With Osteoporosis at High Risk (ARCH) clinical trial (NCT01631214), 1 year of romosozumab followed by alendronate reduced the risk of vertebral and nonvertebral fractures compared to alendronate alone in women with prevalent fracture. We performed post hoc analyses of data from patients in ARCH (romosozumab, n = 1739; alendronate, n = 1726) who had a baseline BMD measurement and received at least one open-label alendronate dose. We evaluated 1-year mean BMD and corresponding T-score changes; proportions of patients achieving T-scores > -2. Read More

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http://dx.doi.org/10.1002/jbmr.3996DOI Listing

Trabecular bone score in patients with chronic kidney disease.

Osteoporos Int 2020 May 21. Epub 2020 May 21.

Rady Faculty of Health Sciences, University of Manitoba, GF324-820 Sherbrook Street, Winnipeg, Manitoba, R3A 1R9, Canada.

Patients with chronic kidney disease have high risk of osteoporotic fractures. Lower trabecular bone score (TBS) was associated with poorer kidney function and higher fracture risk when kidney function was normal. Addition of TBS to The Fracture Risk Assessment Tool with bone mineral density did not improve fracture risk prediction. Read More

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http://dx.doi.org/10.1007/s00198-020-05458-1DOI Listing

Iatrogenic biological fracture of the cervical spine during gradual halo traction for kyphotic deformity correction: case report.

BMC Musculoskelet Disord 2020 May 21;21(1):318. Epub 2020 May 21.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Professorial Block, 5th Floor, 102 Pokfulam Road, Pokfulam, Hong Kong SAR, China.

Background: Severe kyphotic deformities carry high risk for neurological injuries as osteotomies are often required for correction. Surgeons often utilize a staged approach for dealing with these conditions starting with a period of halo traction to stretch tight soft tissues and partially correct the deformity, followed by surgery. Halo traction is a relatively safe procedure and complications are uncommon. Read More

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http://dx.doi.org/10.1186/s12891-020-03350-xDOI Listing

Retrospective analysis of eligibility for denosumab in patients presenting with osteoporotic fractures and renal impairment treated by orthogeriatric service at Middlemore Hospital.

N Z Med J 2020 May 22;133(1515):16-24. Epub 2020 May 22.

Consultant Orthogeriatrician, ARHOP, Counties Manukau Health, Auckland.

Background: Little is known about the prevalence of renal impairment in patients presenting with osteoporotic fractures contraindicating bisphosphonate use in New Zealand, and their eligibility to denosumab.

Aim: To assess the prevalence of renal impairment contraindicating bisphosphonate use in older adults presenting with osteoporotic fractures, differences in demographic variables between those with renal impairment and those who do not, and finally to assess eligibility for denosumab based on the current PHARMAC special authority criteria.

Method: All patients 65 years and older with osteoporotic fractures treated by inpatient orthogeriatric service (IOS) and the outpatient fracture liaison service (FLS) at Middlemore Hospital between 1 February to 31 April 2019 were assessed. Read More

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Traumatic Atlantoaxial Dislocation Without Neurological Deficit.

World Neurosurg 2020 May 16. Epub 2020 May 16.

Louisiana State University Health Science Center - Shreveport, Department of Neurosurgery.

Traumatic atlantoaxial dislocation without associated odontoid fracture or neurological deficit is a rare occurrence. We present the case of a 39-year-old male pedestrian struck by a vehicle who suffered a traumatic grade 4 retrolisthesis of C1-C2. The closed reduction was successful and the patient underwent posterior occipito-cervical fusion. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.064DOI Listing

The incidence and risk factors for adjacent vertebral fractures in community-dwelling people with prevalent vertebral fracture: the 3rd and 4th survey of the ROAD study.

Arch Osteoporos 2020 May 18;15(1):74. Epub 2020 May 18.

Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical & Research Center, The University of Tokyo Hospital, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8655, Japan.

In this 3-year follow-up study of 66 community-dwelling adults with severely deformed vertebral fractures, the annual incidence of adjacent vertebral fracture (AVF) was 6.1%/year. Lower bone mineral density at the femoral neck and spinopelvic malalignment were risk factors for AVF. Read More

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http://dx.doi.org/10.1007/s11657-020-00747-yDOI Listing

Multiple-level cervical spine trauma in children: Case report and literature review.

Trauma Case Rep 2020 Jun 7;27:100298. Epub 2020 May 7.

Manoel André Hospital Complex, Arapiraca, State of Alagoas, Brazil.

Spinal trauma is rare in children, but when it occurs, trauma of the cervical spine corresponds to 60%-80% of all cases. The most common causes of pediatric cervical spine injuries are automobile accidents, sports activities, and leisure-related accidents. Herein we report a surgically-treated case of cervical spine trauma with fractures of multiple vertebrae. Read More

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http://dx.doi.org/10.1016/j.tcr.2020.100298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217991PMC

Bone Evaluation by High-Resolution Peripheral Quantitative Computed Tomography in Patients with Adrenal Incidentaloma.

J Clin Endocrinol Metab 2020 May 15. Epub 2020 May 15.

Department of Internal Medicine and Endocrine Unit, Federal University of Rio de Janeiro, School of Medicine, Clementino Fraga Filho University Hospital, Rio de Janeiro, RJ, Brazil.

Context: Data regarding high-resolution peripheral quantitative computed tomography (HR-pQCT) in patients with adrenal incidentaloma (AI) are unknown.

Purpose: To evaluate the areal bone mineral density (aBMD), microstructure and fractures in patients with nonfunctioning AI (NFAI) and autonomous cortisol secretion (ACS).

Methods: We evaluated 45 patients with NFAI [1mg dexamethasone suppression test (1mg DST ≤1. Read More

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http://dx.doi.org/10.1210/clinem/dgaa263DOI Listing

Effects of follow-on therapy after denosumab discontinuation in patients with postmenopausal osteoporosis.

Mod Rheumatol 2020 May 15:1-21. Epub 2020 May 15.

Department of Orthopaedic Surgery, Toyonaka Municipal Hospital, Osaka, Japan.

Objectives: To clarify the effects of follow-on therapy after denosumab (DMAb) discontinuation.

Methods: In this retrospective, multicenter study, postmenopausal patients with osteoporosis who were previously treated by oral bisphosphonates (BP) (n = 26) or teriparatide (TPTD) (n = 27) were switched to DMAb (administered 2.6 times), and then discontinued. Read More

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http://dx.doi.org/10.1080/14397595.2020.1769895DOI Listing

Aromatase inhibitors attenuate the effect of alendronate in women with breast cancer.

J Bone Miner Metab 2020 May 13. Epub 2020 May 13.

Department of Internal Medicine, Seoul National University College of Medicine, 101 Dae-hak ro, Jongno gu, Seoul, 03080, Republic of Korea.

Introduction: Aromatase inhibitors are known to accelerate bone loss in patients with breast cancer. However, how much AIs affect the efficacy of antiresorptive agents has not been studied. The study aimed to compare the effect of alendronate on bone mineral density (BMD) between patients with and without AI treatment. Read More

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http://dx.doi.org/10.1007/s00774-020-01111-3DOI Listing

Dairy intake is not associated with improvements in bone mineral density or risk of fractures across the menopause transition: data from the Study of Women's Health Across the Nation.

Menopause 2020 May 11. Epub 2020 May 11.

Department of Nutrition Science, Purdue University, West Lafayette, IN.

Objective: Menopause represents a period in which bone deterioration is accelerated; thus, primary prevention strategies to address age-related bone loss are crucial. Dairy products contain more than a dozen essential nutrients, including calcium, phosphorus, vitamin D, and high-quality protein, as well as bioactive compounds that may promote bone mineralization. However, the relationship between dairy consumption and bone health across the menopause transition remains largely unknown. Read More

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http://dx.doi.org/10.1097/GME.0000000000001555DOI Listing

Subaxial Cervical Pedicle Screw in Traumatic Spinal Surgery.

Korean J Neurotrauma 2020 Apr 24;16(1):18-27. Epub 2020 Apr 24.

Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

In cases of unstable cervical traumatic lesions, the biomechanical superiority of the cervical pedicle screw (CPS) allows the lesion to be stabilized effectively. In this study, we review and summarize the indications, technical guidelines, and potential neurovascular complications and their prevention of the use of the CPS for trauma. For patients with fractured lamina or lateral mass, a CPS is reliable for stabilization. Read More

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http://dx.doi.org/10.13004/kjnt.2020.16.e13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192805PMC

Efficacy and safety of Romosozumab in treatment for low bone mineral density: a systematic review and meta-analysis.

Clin Rheumatol 2020 May 8. Epub 2020 May 8.

Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.

Osteoporosis is a chronic skeletal disease with an increasing prevalence. Romosozumab, as a monoclonal anti-sclerostin antibody with a dual function, has been produced. In this meta-analysis, we aimed to examine the efficacy of Romosozumab in patients with low bone mineral density. Read More

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http://dx.doi.org/10.1007/s10067-020-04948-1DOI Listing

Dietary calcium and vitamin K are associated with osteoporotic fracture risk in middle-aged and elderly Japanese women, but not men: the Murakami Cohort Study.

Br J Nutr 2020 May 7:1-25. Epub 2020 May 7.

Division of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Although dietary calcium, vitamin D, and vitamin K are nutritional factors associated with osteoporosis, little is known about their effects on incident osteoporotic fractures in East Asian populations. This study aimed to determine whether intakes of these nutrients predict incident osteoporotic fractures. We adopted a cohort-study design with a 5-year follow-up. Read More

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http://dx.doi.org/10.1017/S0007114520001567DOI Listing

Pediatric Spine Trauma: A Brief Review.

Neurosurgery 2020 May 6. Epub 2020 May 6.

Department of Neurological Surgery, Columbia University, New York, New York.

Pediatric spinal trauma is a broad topic with nuances specific to each anatomic region of the spinal column. The purpose of this report is to provide a brief review highlighting the most important and common clinical issues regarding the diagnosis and management of pediatric spine trauma. Detailed descriptions of imaging findings along with specific operative and nonoperative management of each fracture and dislocation type are beyond the scope of this review. Read More

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http://dx.doi.org/10.1093/neuros/nyaa119DOI Listing

Osteoporosis medication use among Australian women over two decades.

Arch Osteoporos 2020 May 6;15(1):67. Epub 2020 May 6.

IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, Australia.

Despite the burden of osteoporosis and treatment availability, a treatment gap remains. Women in a population-based study were followed with respect to use of anti-fracture medication over two decades. Use increased over time but remained suboptimal, with less than 20% of those at high risk of fracture receiving treatment. Read More

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http://dx.doi.org/10.1007/s11657-019-0661-7DOI Listing

The effect of bisphosphonates on managing osteoporosis after spinal cord injury: a meta-analysis.

Curr Pharm Des 2020 May 4. Epub 2020 May 4.

Trauma & Orthopaedics Department, Shanxi Bethune Hospital, Taiyuan, Shanxi Province. China.

Background: The increased bone loss after spinal cord injury (SCI) is associated with an increase in the morbidity and mortality of fragility fractures, which can constitute a substantial cost to health care systems. Bisphosphonates (BPs) are now the principal class of medications used for osteoporosis.

Objective: To demonstrate the effect of BPs on treating osteoporosis after SCI. Read More

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http://dx.doi.org/10.2174/1381612826666200504115747DOI Listing
May 2020
3.452 Impact Factor

Once-yearly zoledronic acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial.

Osteoporos Int 2020 May 2. Epub 2020 May 2.

Menzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, Tasmania, 7000, Australia.

This study evaluated whether zoledronic acid (ZA) inhibited the progression of abdominal aortic calcification (AAC) over 3 years in 502 postmenopausal women with osteoporosis. AAC progressed in a similar proportion of participants in the ZA (29%) and placebo (31%) groups, suggesting no effect of ZA on AAC progression.

Introduction: Bisphosphonate use is associated with reduced risk of all-cause mortality and cardiovascular events. Read More

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http://dx.doi.org/10.1007/s00198-020-05430-zDOI Listing

Stingray spear injury to the pediatric spinal cord: case report and review of the literature.

Childs Nerv Syst 2020 May 2. Epub 2020 May 2.

Servicio de Neurocirugía, Hospital Nacional de Niños, "Dr. Carlos Sáenz Herrera", San José, Costa Rica.

Stingray injuries are rare, mostly causing injuries to the lower extremities but occasionally fatal if there is direct puncture of the thorax, abdomen, or neck. Direct combined stingray injury to the central nervous system has not been reported in the literature. Herein we present the case of a 12-year-old boy who, while wading at the seashore of the Costa Rica's Pacific Ocean, sustained a combined oblique penetrating injury to the C6 vertebra caused by a Stingray. Read More

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http://dx.doi.org/10.1007/s00381-020-04629-zDOI Listing

Treatment strategy of unstable atlas fracture: A retrospective study of 21 patients.

Medicine (Baltimore) 2020 May;99(18):e20153

Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi.

At present, the posterior cervical approach with open reduction and internal fixation (ORIF) remains a commonly effective treatment for unstable Atlas fracture. However, the inserted screws into the C1 lateral mass of some unstable atlas fracture are very difficult, so that the operation is forced to change into C0 to C2 fusion. In order to improve the successful rate of lateral mass screw placement, we introduced a method of fixing lateral mass with a towel clamp in posterior transpedicular fixation, and explore the efficacy and feasibility. Read More

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http://dx.doi.org/10.1097/MD.0000000000020153DOI Listing

The Anterior Transarticular Fixation of C1/C2 in the Elderly With Dens Fractures.

Int J Spine Surg 2020 Apr 30;14(2):162-169. Epub 2020 Apr 30.

Department of Neurosurgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Background: Anterior transarticular screw fixation (ATSF) of C1/C2 can be used for the treatment of unstable dens fractures. Here, we evaluated the feasibility of an anterior C1/C2 fixation in elderly patients with unstable dens fractures. Furthermore, we tried to analyze safe entry zones for ATSF surgery. Read More

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http://dx.doi.org/10.14444/7031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188103PMC

Nonoperative treatment of traumatic spinal injuries in Tanzania: who is not undergoing surgery and why?

Spinal Cord 2020 Apr 29. Epub 2020 Apr 29.

Weill Cornell Brain and Spine Center, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA.

Study Design: Retrospective, cohort study of a prospectively collected database.

Objectives: In a cohort of patients with traumatic spine injury (TSI) in Tanzania who did not undergo surgery, we sought to: (1) describe this nonoperative population, (2) compare outcomes to operative patients, and (3) determine predictors of nonoperative treatment.

Setting: Tertiary referral hospital. Read More

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http://dx.doi.org/10.1038/s41393-020-0474-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222864PMC
April 2020
1.699 Impact Factor

Ankylosing spondylitis - specific aspects related to surgical treatment of cervical fracture - case report.

Authors:
J Kašík P Vaněk

Rozhl Chir 2020 ;99(2):86-90

Ankylosing spondylitis (AS) or else Bechterews or Marie-Strümpells disease is a chronic inflammatory autoimmune disease affecting preferentially the spine in the form of sacroileitis and spondylitis [1,2]. Due to acquired skeletal fragility, compared to healthy spine there is a significantly different response of the organism to the mechanical load [3] and therefore in patients with AS, spinal trauma is much more dangerous. Unlike predominantly elastic injuries in healthy cervical spine in AS patients this elasticity is lost and the spine then behaves like a tubular bone [4,5]. Read More

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http://dx.doi.org/10.33699/PIS.2020.99.2.86-90DOI Listing
January 2020

Pragmatic Strategy Empowering Paramedics to Assess Low-Risk Trauma Patients With the Canadian C-Spine Rule and Selectively Transport Them Without Immobilization: Study Protocol for a Stepped-Wedge Cluster Randomized Trial.

JMIR Res Protoc 2019 Dec 31. Epub 2019 Dec 31.

Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, 1053 Carling Ave. Rm F649Civic Campus, Ottawa, CA.

Background: Each year, half a million patients with a potential neck (c-spine) injury are transported to Ontario emergency departments (EDs). Less than 1.0% (1/100) of these patients have a neck bone fracture. Read More

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http://dx.doi.org/10.2196/16966DOI Listing
December 2019

Feasibility and Safety of Cervical Kinematic Magnetic Resonance Imaging in Patients with Cervical Spinal Cord Injury without Fracture and Dislocation.

Orthop Surg 2020 Apr;12(2):570-581

Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Shaoguan, China.

Objective: To evaluate the feasibility and safety of cervical kinematic MRI (KMRI) in patients with cervical spinal cord injury without fracture and dislocation (CSCIWFD).

Methods: This was a single-institution case-only study. Patients with CSCIWFD were enrolled in our institution from February 2015 to July 2019. Read More

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http://dx.doi.org/10.1111/os.12663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189030PMC

Whole Spine CT Scan for the Detection of Acute Spinal Fractures in Diffuse Idiopathic Skeletal Hyperostosis Patients Who Sustained Low-energy Trauma.

Spine (Phila Pa 1976) 2020 Apr 23. Epub 2020 Apr 23.

Departments of Diagnostic Imaging and.

Study Design: Retrospective cohort study.

Objective: To evaluate the role and value of whole-spine computerized tomography (WSCT) vs. radiographs and targeted CT to tender spinal regions in patients with diffuse idiopathic skeletal hyperostosis (DISH) after low-energy trauma. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003536DOI Listing

Elderly Patients With Cervical Spine Fractures After Ground Level Falls Are at Risk for Blunt Cerebrovascular Injury.

J Surg Res 2020 Apr 24;253:100-104. Epub 2020 Apr 24.

Department of Surgery, NYU Langone Health, Bellevue Hospital Center, New York, New York.

Background: Osteopenia is common in the elderly, increasing their risk of sustaining cervical fractures after ground level falls (GLFs). We sought to examine the incidence of blunt cerebrovascular injury (BCVI) and subsequent stroke in elderly GLF patients as compared with other higher injury mechanisms.

Materials And Methods: The Trauma Quality Improvement Program database (2011-2016) was used to identify blunt trauma patients with isolated (other body region abbreviated injury scale <3) cervical spine (C1-C7) fractures. Read More

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http://dx.doi.org/10.1016/j.jss.2020.03.036DOI Listing

Loading modality and age influence teriparatide-induced bone formation in the human femoral neck.

Bone 2020 Jul 21;136:115373. Epub 2020 Apr 21.

Department of Medicine, Columbia University, 622 West 168th St., New York, NY 10032, USA. Electronic address:

Teriparatide (TPTD) reduces risk of both vertebral and nonvertebral fracture, but increases bone mineral density (BMD) much more at the spine than the hip. TPTD and mechanical loading may have a synergistic anabolic effect on BMD, which may help explain these site-specific differences. Under normal daily activity, the femoral neck (FN) is under bending, placing one side under tension and the other under compression. Read More

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http://dx.doi.org/10.1016/j.bone.2020.115373DOI Listing

The efficacy and safety of bisphosphonates for osteoporosis in women older than 65 years: a meta-analysis.

Authors:
Qin Fan Junjie Wang

Curr Pharm Des 2020 Apr 22. Epub 2020 Apr 22.

Changzhi Medical College, Changzhi, Shanxi Province. China.

Background: Osteoporosis presents a major threat to the health of women older than 65 years. Bisphosphonates (BPs) are now the principal class of medications for osteoporosis.

Objective: To evaluate the efficacy and safety of BPs in women older than 65 years. Read More

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http://dx.doi.org/10.2174/1381612826666200423092602DOI Listing

Is Anterior-Only Fixation Adequate for Three-Column Injuries of the Cervical Spine?

Asian Spine J 2020 Apr 24. Epub 2020 Apr 24.

Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, India.

Study Design: Retrospective case series.

Purpose: To analyze the clinical and functional outcomes of patients who have undergone anterior cervical discectomy/corpectomy and fusion (ACDF/ACCF) for a three-column cervical spine injury (CSI).

Overview Of Literature: The treatment of choice for a three-column CSI is an area of contention; however, combined anterior and posterior fixation is the preferred method explored in the literature. Read More

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http://dx.doi.org/10.31616/asj.2019.0225DOI Listing

Epidural hematoma due to Gardner-Wells Tongs placement during pediatric spinal deformity surgery.

Spine Deform 2020 Apr 20. Epub 2020 Apr 20.

Department of Orthopaedic Surgery, Columbia University College of Physicians and Surgeons, 5141 Broadway, New York, NY, 10034, USA.

Background: To our knowledge, this is the first documented report of an operative cranial epidural hematoma secondary to skull fracture due to placement of Gardner-Wells Tongs (GWT) in the setting of a spinal deformity reconstruction.

Purpose: The objective is to illustrate the possibility of cranial pathology secondary to GWT placement and the need to properly correlate intraoperative neuromonitoring findings.

Study Design: Case report. Read More

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http://dx.doi.org/10.1007/s43390-020-00116-2DOI Listing

Posterior osteotomy techniques for rigid cervical deformity correction.

J Spine Surg 2020 Mar;6(1):274-279

Department of Neurological Surgery, University of California, San Francisco, CA, USA.

Posterior cervical osteotomies are powerful techniques for the correction of rigid cervical deformity. These include a variety of subtypes including partial facet joint resection, complete facet joint resection, opening wedge osteotomy (OWO), and closing wedge osteotomy (CWO). The partial facet joint resection provides limited lordosis but can be applied across multiple levels and provides bony surface for fusion. Read More

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http://dx.doi.org/10.21037/jss.2020.01.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154347PMC

Finite element analysis to determine the cause of ring fractures in a motorcyclist's head.

Leg Med (Tokyo) 2020 Apr 7;45:101697. Epub 2020 Apr 7.

Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, Ministry of Justice, 1347 West Guangfu Road, Shanghai, China. Electronic address:

The finite element (FE) method can potentially help in reconstructing skull fracture biomechanisms, enabling differentiation of the injury patterns caused by traffic accidents. This study aims to (1) reconstruct a motorcycle driver-car accident case using the total human model for safety and FE simulations; and (2) analyze the biomechanisms of fatal ring fractures in the motorcyclist's skull base to determine if the fatal craniocerebral injuries were caused by a fall onto the highway after hitting a pedestrian or by the subsequent impact of a car. We simulated a series of loading scenarios of falls onto the road and impacts by a car, with and without a helmet being used. Read More

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http://dx.doi.org/10.1016/j.legalmed.2020.101697DOI Listing
April 2020
1.441 Impact Factor

Imaging of cranio-cervical junction traumas.

Eur J Radiol 2020 Jun 19;127:108960. Epub 2020 Mar 19.

Neuroradiology Department, A. Cardarelli Hospital, Napoli, Italy.

The craniocervical junction (CCJ) or upper cervical spine (UCS) has anatomic features and a biomechanics completely different from the other spinal segment of the spine. Several ligaments and muscles control its motion and function and ensure the maximum mobility and the visual and auditory spatial exploration. UCS traumas represent approximately one-third of all cervical spine injuries. Read More

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http://dx.doi.org/10.1016/j.ejrad.2020.108960DOI Listing

Effects of glucocorticoids on osteoporosis in rheumatoid arthritis: a systematic review and meta-analysis.

Osteoporos Int 2020 Apr 14. Epub 2020 Apr 14.

Department of Gastroenterology, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu Province, People's Republic of China.

We evaluated the effects of glucocorticoids on bone mineral density (BMD), and prevalence of osteoporosis and fracture in rheumatoid arthritis (RA) by meta-analysis. Until June 26, 2019, we conducted a systematic literature search in EMBASE, Web of science, PubMed, and Cochrane Library to obtain BMD and the prevalence of osteoporosis and fracture in glucocorticoid-treated subjects with RA. The BMD of the treatment and control groups were analyzed by meta-analysis (Stata. Read More

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http://dx.doi.org/10.1007/s00198-020-05360-wDOI Listing

Surgical treatment of atlantoaxial subluxation by intraoperative skull traction and C1-C2 fixation.

BMC Musculoskelet Disord 2020 Apr 14;21(1):239. Epub 2020 Apr 14.

Department of Orthopedics, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, 266003, Shandong Province, People's Republic of China.

Background: Atlantoaxial subluxation (AAS) is a not rare abnormality between the atlas (C1) and axis (C2). For AAS patients with persistent neck pain and neurologic symptoms, surgical intervention is a good choice. Nevertheless, there were still few reports about the use of intraoperative skull traction and different fixation methods in treatment of AAS. Read More

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http://dx.doi.org/10.1186/s12891-020-03273-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158009PMC

Effects of supervised high-intensity resistance and impact training or machine-based isometric training on regional bone geometry and strength in middle-aged and older men with low bone mass: The LIFTMOR-M semi-randomised controlled trial.

Bone 2020 Jul 11;136:115362. Epub 2020 Apr 11.

Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia; School of Allied Health Sciences, Griffith University, Gold Coast, Queensland, Australia; The Bone Clinic, Brisbane, Queensland, Australia. Electronic address:

Introduction: Few data exist on the effects of bone-targeted exercise on geometric and biomechanical indices of bone strength in men. The Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men (LIFTMOR-M) trial was designed to compare the efficacy and safety of two novel, supervised, twice-weekly, high-intensity exercise programs in middle-aged and older men with osteopenia and osteoporosis on musculoskeletal health and risk factors related to falls and fractures. The current report includes secondary outcomes of the LIFTMOR-M exercise intervention trial. Read More

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http://dx.doi.org/10.1016/j.bone.2020.115362DOI Listing

Weight gain after curative parathyroidectomy predicts increase in bone mineral density in patients with symptomatic primary hyperparathyroidism.

Clin Endocrinol (Oxf) 2020 Apr 14. Epub 2020 Apr 14.

Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Primary hyperparathyroidism (PHPT) results in reduction of bone mineral density (BMD) and an increased risk of pathological fractures. Curative surgery does improve BMD; however, the magnitude of rise and predictive factors are highly variable amongst the hitherto available studies.

Objectives: To quantify the magnitude of improvement in BMD after curative surgery in patients with symptomatic PHPT and dissect out the possible clinical and biochemical parameters predicting the BMD rise. Read More

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http://dx.doi.org/10.1111/cen.14195DOI Listing
April 2020
3.457 Impact Factor

Comparison between teriparatide and bisphosphonates for improving bone mineral density in postmenopausal osteoporosis patients: A meta-analysis.

Medicine (Baltimore) 2020 Apr;99(15):e18964

Department of Orthopaedics, Suzhou Kowloon Hospital of Shanghai Jiangtong University School of Medicine.

Background: We performed a systematic review and meta-analysis of the efficacy and safety of teriparatide and bisphosphonates in managing postmenopausal osteoporosis.

Methods: PubMed, EMBASE, Web of Science, and China National Knowledge Infrastructure were searched for relevant randomized controlled trials that were published before April 2018 and compared teriparatide and bisphosphonates in treating postmenopausal osteoporosis. Stata 12. Read More

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http://dx.doi.org/10.1097/MD.0000000000018964DOI Listing

Prognostic value of laboratory values in older patients with cervical spine fractures.

Clin Neurol Neurosurg 2020 Apr 4;194:105781. Epub 2020 Apr 4.

Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, United States. Electronic address:

Objectives: To understand the prognostic value of laboratory markers at presentation on post-treatment survival of patients 50 and older following cervical spine fracture.

Patients And Methods: We obtained clinical data on patients 50 and older treated for cervical spine fracture in a single healthcare system (2006-2016). Our primary outcome consisted of 1-year mortality, with mortality within 3-months of presentation considered secondarily. Read More

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http://dx.doi.org/10.1016/j.clineuro.2020.105781DOI Listing

Vertebral Artery Injury with Coinciding Unstable Cervical Spine Trauma: Mechanisms, Evidence-based Management, and Treatment Options.

Cureus 2020 Mar 9;12(3):e7225. Epub 2020 Mar 9.

Neurological Surgery, University of Florida College of Medicine, Gainesville, USA.

Unstable traumatic cervical spine fracture is a commonly encountered neurosurgical issue. Concomitant vertebral artery injuries present a challenge in surgical decision-making regarding the timing and order of surgical intervention with respect to endovascular intervention and internal fixation of the unstable fracture. Currently, there are no studies that have specifically examined stroke rate or outcomes for patients who have vertebral artery injuries and unstable cervical spine fractures with respect to temporal treatment course. Read More

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http://dx.doi.org/10.7759/cureus.7225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141798PMC

Bone Mineral Density and Risk of Osteoporotic Fractures in Women with Parkinson's Disease.

J Osteoporos 2020 25;2020:5027973. Epub 2020 Mar 25.

Department of Clinical Physiology & Pathology of Extrapiramide Nervous System, SI "D. F. Chebotarev Institute of Gerontology NAMS of Ukraine", Kyiv, Ukraine.

Osteoporosis and Parkinson's disease (PD) are two important age-related diseases, which have an influence on pain, physical activity, disability, and mortality. The aim of this research was to study the parameters of bone mineral density (BMD), frequency, and 10-year probability of osteoporotic fractures (OFs) in females with Parkinson's disease (PD). We have examined 113 postmenopausal women aged 50-74 years old which were divided into 2 groups (I, control group (CG),  = 53 and II, subjects with PD,  = 60). Read More

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http://dx.doi.org/10.1155/2020/5027973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132579PMC