10,081 results match your criteria Fracture Cervical Spine


Damage control orthopedics applied in an 8-year-old child with life-threatening multiple injuries: A CARE-compliant case report.

Medicine (Baltimore) 2019 Apr;98(16):e15294

University Children's Hospital Basel (UKBB), Department of Pediatric Surgery, 4056 Basel.

Rationale: Damage control is a staged surgical approach to manage polytraumatized patients. The damage control approach comprises three steps. First, bleeding is controlled and fractures are stabilized temporarily; second, vital parameters are stabilized and the child is rewarmed in the intensive care unit; and third, the child is reoperated for definitive repair of injuries. Read More

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http://Insights.ovid.com/crossref?an=00005792-201904190-0005
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http://dx.doi.org/10.1097/MD.0000000000015294DOI Listing
April 2019
2 Reads

Breakage of metal hip arthroplasty components: Retrieval and structural analysis.

Biomed Mater Eng 2019 Apr 12. Epub 2019 Apr 12.

Department of General Orthopaedics, Musculoskeletal Oncology and Trauma Surgery, Poznan University of Medical Sciences, Poznan, Poland.

Background: Breakage of joint arthroplasty components are rare, yet during an implant retrieval program we found several cases.

Objective: In this study we examined the components to determine the causes and mechanisms of breakage of these implants.

Methods: From our collection of 849 retrievals we selected 682 cases with metal parts (503 hip, 79 knee arthroplasties) and identified fractured components: seven hip resurfacing implants, five total hip replacement stems, one monopolar femoral head, and one modular revision femoral stem from. Read More

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http://dx.doi.org/10.3233/BME-191053DOI Listing

Hangman's fracture: Management strategy and healing rate in a prospective multi-centre observational study of 34 patients.

Orthop Traumatol Surg Res 2019 Apr 17. Epub 2019 Apr 17.

Société Française de Chirurgie Rachidienne, 56, rue Boisonnade, 75014 Paris, France.

Background: Hangman's fractures account for 15% to 20% of all cervical spine fractures. The grading system developed by Effendi and modified by Levine and Edwards is generally used as the basis for management decisions. Nonetheless, the optimal management remains controversial. Read More

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http://dx.doi.org/10.1016/j.otsr.2019.03.009DOI Listing

Bone mineral density in patients with longstanding type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.

J Diabetes Complications 2018 Dec 22. Epub 2018 Dec 22.

Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. Electronic address:

Aim: It is currently unclear if longstanding type 1 diabetes (T1D) affects bone mineral density (BMD).

Methods: BMD measured by dual-energy X-ray absorptiometry and history of fragility fracture was determined in 75 T1D participants with ≥50 years of diabetes duration and 75 age- and sex-matched non-diabetic controls. BMD T-scores were determined for the lumbar spine (LS), total hip (TH) and femoral neck (FN). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10568727183108
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http://dx.doi.org/10.1016/j.jdiacomp.2018.12.009DOI Listing
December 2018
1 Read

3D Computed Tomography Mapping of Thoracolumbar Vertebrae Fractures.

Med Sci Monit 2019 Apr 16;25:2802-2810. Epub 2019 Apr 16.

Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China (mainland).

BACKGROUND Fractures of the thoracolumbar (TL) spine represent 90% of all spinal fractures, followed by cervical and lumbar spine fractures. This study aimed to create fracture maps of the traumatic thoracolumbar (TL) fracture vertebral body (T12-L2) through the use of CT mapping as a big data visualization method to reveal recurrent patterns and characteristics of traumatic TL fractures. MATERIAL AND METHODS A consecutive series of 174 fractured vertebrae (T12-L2) was used to create three-dimensional (3D) reconstruction images, which were superimposed and oriented to fit a model vertebral template by aligning specific bio-landmarks and reducing reconstructed fracture fragments. Read More

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http://dx.doi.org/10.12659/MSM.915916DOI Listing

Range of motion in the cervical spine after odontoid fracture treated with anterior screw fixation.

J Orthop Surg Res 2019 Apr 15;14(1):104. Epub 2019 Apr 15.

Medical Faculty, University of Rzeszów, Kopisto 2A Avenue, 35-959, Rzeszow, Poland.

Background: It is believed that direct odontoid screw fixation preserves the physiological cervical range of motion following surgery. However, there are no clinical studies confirming the motion sparing value of this technique. This study aims to (1) to assess active cervical range of motion following types II and III odontoid fracture, successfully treated with anterior odontoid screw fixation, and (2) to examine the relationship between the range of motion of the head and duration of collar usage, neck pain, quality of life, and patients' age. Read More

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http://dx.doi.org/10.1186/s13018-019-1135-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466774PMC

Reliability and Validity of the AOSpine Thoracolumbar Injury Classification System: A Systematic Review.

Global Spine J 2019 Apr 15;9(2):231-242. Epub 2018 Oct 15.

University of Southern California, Los Angeles, CA, USA.

Study Design: Systematic review.

Objectives: The AOSpine thoracolumbar injury classification system (ATLICS) is a relatively simple yet comprehensive classification of spine injuries introduced in 2013. This systematic review summarizes the evidence on measurement properties of this new classification, particularly the reliability and validity of the main morphologic injury types with and without inclusion of the subtypes. Read More

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http://dx.doi.org/10.1177/2192568218806847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448204PMC

Effects of SGLT2 inhibitors on fractures and bone mineral density in type 2 diabetes mellitus: an updated meta-analysis.

Diabetes Metab Res Rev 2019 Apr 15:e3170. Epub 2019 Apr 15.

NHC Key Laboratory of Hormones and Development (Tianjin Medical University), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China.

Aims: To update and determine the effects of sodium glucose co-transporter 2 (SGLT2) inhibitor therapy on fracture and bone mineral density (BMD) in type 2 diabetes mellitus (T2DM) patients.

Materials And Methods: We identified 27 eligible randomized controlled trials (RCTs) that compared the efficacy and safety of SGLT2 inhibitors to a placebo in 20895 T2DM participants, with an average duration of 64.22 weeks. Read More

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http://dx.doi.org/10.1002/dmrr.3170DOI Listing
April 2019
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Multidetector CT of Laryngeal Injuries: Principles of Injury Recognition.

Radiographics 2019 Apr 12:180076. Epub 2019 Apr 12.

From the Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115.

Blunt laryngeal trauma is associated with high morbidity and mortality. However, owing to their relatively rare occurrence, laryngeal injuries may be missed or underdiagnosed. Even subtle abnormalities at multidetector CT may correspond to significant functional abnormalities. Read More

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http://dx.doi.org/10.1148/rg.2019180076DOI Listing

Disappearance of Anterior Cervical Corpectomy Cage.

Cureus 2019 Jan 30;11(1):e3985. Epub 2019 Jan 30.

Neurosurgery, Taipei Veterans General Hospital, Taipei, TWN.

Although cage subsidence and dislodgement are not uncommon in anterior cervical spine surgery, missing cages have seldom been reported. This is the first report of the disappearance of a metallic corpectomy cage after anterior cervical fusion. A 63-year-old man, who had a history of ankylosing spondylitis and diabetes mellitus, was involved in a motor vehicle accident that broke his neck. Read More

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https://www.cureus.com/articles/17446-disappearance-of-anter
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http://dx.doi.org/10.7759/cureus.3985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443108PMC
January 2019
3 Reads

Progression of local kyphosis after conservative treatment for compressive cervical spine fracture with spinal cord injury.

J Orthop Surg Res 2019 Apr 11;14(1):98. Epub 2019 Apr 11.

Departments of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashiku, Fukuoka, 812-8582, Japan.

Introduction: Compressive-flexion type cervical spine fracture is typically accompanied by apparent dislocation of the facet joints, undesirable cervical alignment, and devastating neurological dysfunction, which provides strong rationale for rendering prompt operative treatment. However, the validity of conservative treatment for compressive-flexion cervical spine injury in cases with preserved congruity of the facet joints has yet to be elucidated. The purpose of this study is to evaluate the long-term outcome of cervical alignment following conservative treatment for compressive-flexion cervical spine injury with preserved congruity of the facet joints. Read More

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http://dx.doi.org/10.1186/s13018-019-1115-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458645PMC

Association between Cervical Spine Degeneration and the Presence of Dens Fractures.

Z Orthop Unfall 2019 Apr 9. Epub 2019 Apr 9.

Department of Orthopaedics and Rehabilitation, Oregon Health and Science University, Portland, Oregon, United States.

Purpose: Results of a small case series indicate an increased risk of dens fractures in patients with osteoarthritis. The purpose of this retrospective cohort study was to analyze the relative risks associated with degeneration of the cervical spine in the occurrence of dens fractures in older patients.

Methods: We performed a retrospective CT study of 1,794 patients > 55 years of age with and without dens fractures for signs of osteoarthritis (OA). Read More

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http://dx.doi.org/10.1055/a-0853-8046DOI Listing
April 2019
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Comparison between postmortem computed tomography and autopsy in the detection of traumatic head injuries.

J Neuroradiol 2019 Apr 4. Epub 2019 Apr 4.

Pôle Universitaire d'Imagerie Post-Mortem, Université Paris Descartes-Paris 5, Sorbonne Paris Cité, 12 rue de l'Ecole de Médecine, 75006 Paris, France; Institut Médico-Légal de Paris, 2 place Mazas, 75012 Paris, France; CNRS UMR 5288 Institut National de la Transfusion Sanguine, 6 rue Cabanel, 75015 Paris, France.

Introduction: - The aim of this study was to assess the agreement between postmortem computed tomography (PMCT) and autopsy in detecting traumatic head injuries.

Materials And Methods: - Consecutive cases of death that underwent both unenhanced PMCT and conventional autopsy were collected from our institution database during a period of 3 years and reviewed retrospectively. PMCT images were reviewed for the presence of fractures (cranial vault, skull base, facial bones and atlas/axis) and intracranial hemorrhage. Read More

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http://dx.doi.org/10.1016/j.neurad.2019.03.008DOI Listing
April 2019
2 Reads

Healing of type II odontoid fracture without surgery in an octogenarian - Case report and literature review.

J Clin Neurosci 2019 Mar 30. Epub 2019 Mar 30.

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, United States. Electronic address:

Odontoid fractures are the most common cervical spine fracture in the elderly. There is considerable controversy regarding the optimal management of type II odontoid fractures in this population. We present the case of an 89-year-old woman presented with neck pain after a mechanical fall. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.03.049DOI Listing
March 2019
1 Read

Type 1 diabetes onset at young age is associated with compromised bone quality.

Bone 2019 Mar 29;123:260-264. Epub 2019 Mar 29.

Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States of America.

Women with type 1 diabetes (T1D) are at increased risk for fracture. We studied the association of T1D and young age at T1D onset (T1D onset before 20 years) on bone structural quality. 24 postmenopausal women with T1D (mean age 60. Read More

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http://dx.doi.org/10.1016/j.bone.2019.03.039DOI Listing
March 2019
2 Reads

Spectrum of diagnostic errors in cervical spine trauma imaging and their clinical significance.

Emerg Radiol 2019 Mar 31. Epub 2019 Mar 31.

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

Purpose: To describe and categorize diagnostic errors in cervical spine CT (CsCT) interpretation performed for trauma and to assess their clinical significance.

Methods: All CsCTs performed for trauma with diagnostic errors that came to our attention based on clinical or imaging follow-up or quality assurance peer review from 2004 to 2017 were included. The number of CsCTs performed at our institution during the same time interval was calculated. Read More

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http://dx.doi.org/10.1007/s10140-019-01685-0DOI Listing
March 2019
2 Reads

Bone mineral density, bone turnover markers, and incident fractures in de novo kidney transplant recipients.

Kidney Int 2019 Mar 4. Epub 2019 Mar 4.

Department of Nephrology and Renal Transplantation, University Hospitals Leuven and Laboratory of Nephrology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

Kidney transplant recipients are at increased risk of fractures. This prospective observational study investigated whether areal bone mineral density (aBMD) as assessed by dual-energy x-ray absorptiometry can predict incident fragility fractures in de novo kidney transplant recipients and whether bone turnover markers increase diagnostic accuracy. Parameters of bone mineral metabolism including parathyroid hormone (PTH), fibroblast growth factor 23, sclerostin, calcidiol and calcitriol, and bone turnover markers were assessed in blood samples collected immediately prior to kidney transplantation in 518 adult recipients. Read More

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http://dx.doi.org/10.1016/j.kint.2018.12.024DOI Listing
March 2019
1 Read

[One stage temporary atlantoaxial segmental fixation and reduction for Grauer type IIB dens fractures in teenagers].

Zhongguo Gu Shang 2019 Mar;32(3):254-259

Department of Spinal Surgery, Ningbo No.6 Hospital, Ningbo 315040, Zhejiang, China;

Objective: To assess the clinical results of one stage temporary atlantoaxial segmental fixation and reduction for Grauer type IIB dens fractures in teenagers.

Methods: From February 2009 to April 2015, 19 teenagers with Grauer type IIB dens fractures not amenable to anteiror screw fixation were enrolled and treated using one stage temporary atlantoaxial segmental fixation and reduction without fusion. There were 14 males and 5 females, aged from 14 to 32 years with an average of (24. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2019.03.012DOI Listing
March 2019
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Complete remodelling of a displaced odontoid synchondrosis fracture managed conservatively: a case report.

J Pediatr Orthop B 2019 Mar 27. Epub 2019 Mar 27.

Welsh Centre for Spinal Trauma and Surgery, University Hospital of Wales, Cardiff.

Odontoid synchondrosis fractures are the most common cervical fracture in young children, although their overall incidence is rare. Various strategies have been proposed in the management of injuries with significant displacement or angulation. In this report, we present the long-term functional and radiological outcomes following nonoperative treatment of such a fracture in a 5-year-old female. Read More

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http://dx.doi.org/10.1097/BPB.0000000000000623DOI Listing
March 2019
0.656 Impact Factor

Ultrasound-based estimates of cortical bone thickness and porosity are associated with non-traumatic fractures in postmenopausal women: A pilot study.

J Bone Miner Res 2019 Mar 26. Epub 2019 Mar 26.

Sorbonne Université, CNRS, INSERM, Laboratoire d'Imagerie Biomédicale, F-75006, Paris, France.

Recent ultrasound axial transmission techniques exploit the multimode waveguide response of long bones to yield estimates of cortical bone structure characteristics. This pilot cross-sectional study aimed to evaluate the performance at the one-third distal radius of a bidirectional axial transmission (BDAT) device to discriminate between fractured and non-fractured postmenopausal women. Cortical thickness (Ct. Read More

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http://dx.doi.org/10.1002/jbmr.3733DOI Listing
March 2019
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There has to be an easier way: facet fracture characteristics that reliably differentiate AOSpine F1 and F2 injuries.

Emerg Radiol 2019 Mar 25. Epub 2019 Mar 25.

Department of Diagnostic and Interventional Imaging, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, 2.130B, Houston, TX, 77030, USA.

Purpose: To identify morphologic features of isolated cervical spine facet fractures that can reliably differentiate AOSpine F1 and F2 injuries.

Materials And Methods: Retrospective review of cervical spine CTs on all patients who sustained isolated cervical fractures of the facets presenting to our level 1 trauma center from August 2012 through December 2015. CTs were reviewed for facet fracture characteristics and AOSpine facet fracture classification. Read More

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http://dx.doi.org/10.1007/s10140-019-01684-1DOI Listing

Frequency of Cervical Spine Injuries in Pediatric Craniomaxillofacial Trauma.

J Oral Maxillofac Surg 2019 Feb 27. Epub 2019 Feb 27.

Adjunct Professor, Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD; Professor, Department of General Surgery, Division of Plastic Surgery, Rush Medical Center, Chicago, IL. Electronic address:

Purpose: In pediatric patients with craniomaxillofacial (CMF) trauma, evaluation for cervical spine injury (CSI) is critical, but there are no studies investigating CSI in this unique population. The aim of this study was to measure the frequency of CSI in the pediatric CMF fracture population.

Materials And Methods: A retrospective cohort study of all pediatric patients who presented to the Johns Hopkins Hospital Emergency Department (Baltimore, MD) with CMF fractures were examined for concurrent CSIs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391193024
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http://dx.doi.org/10.1016/j.joms.2019.02.034DOI Listing
February 2019
10 Reads

Incorporating loading variability into in vitro injury analyses and its effect on cumulative compression tolerance in porcine cervical spine units.

J Biomech 2019 Mar 18. Epub 2019 Mar 18.

Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada. Electronic address:

During repetitive movement, low-back loading exposures are inherently variable in magnitude. The current study aimed to investigate how variation in successive compression exposures influences cumulative load tolerance in the spine. Forty-eight porcine cervical spine units were randomly assigned to one of six combinations of mean peak compression force (30%, 50%, 70% of the predicted tolerance) and loading variation (consistent peak amplitude, variable peak amplitude). Read More

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http://dx.doi.org/10.1016/j.jbiomech.2019.03.011DOI Listing

Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years.

Osteoporos Int 2019 Mar 21. Epub 2019 Mar 21.

Department of Nutritional Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK.

We undertook a systematic review and meta-analysis of published papers assessing dietary protein and bone health. We found little benefit of increasing protein intake for bone health in healthy adults but no indication of any detrimental effect, at least within the protein intakes of the populations studied. This systematic review and meta-analysis analysed the relationship between dietary protein and bone health across the life-course. Read More

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http://dx.doi.org/10.1007/s00198-019-04933-8DOI Listing
March 2019
2 Reads

Is routine MRI of the spine necessary in trauma patients with ankylosing spinal disorders or is a CT scan sufficient?

Spine J 2019 Mar 16. Epub 2019 Mar 16.

Department of Orthopaedics and Sport Medicine, Harborview Medical Center, 325 Ninth Avenue Seattle, WA 98104, USA. Electronic address:

Background: Ankylosing spinal disorder (ASD) patients are at a greater risk for spinal fractures due to osteoporosis and rigidity of the spinal column. These fractures are associated with a high risk of neurologic compromise resulting from delayed or missed diagnoses. Although computed tomography (CT) is usually the initial imaging modality, magnetic resonance imaging (MRI) has been proposed as mandatory to help identify spinal injuries in ASD patients with unexplained neck or back pain or known injuries to help identify noncontiguous fractures. Read More

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http://dx.doi.org/10.1016/j.spinee.2019.03.004DOI Listing
March 2019
5 Reads

Teriparatide versus bisphosphonates for treatment of postmenopausal osteoporosis: A meta-analysis.

Int J Surg 2019 Mar 16. Epub 2019 Mar 16.

Department of Rheumatology, Dongguan People's Hospital,Southern Medical University, 523059.

Objective: This meta-analysis aims to compare the efficacy of teriparatide and bisphosphonates for reducing vertebral fracture risk and bone mineral density (BMD) in lumbar spine and femoral neck in postmenopausal women with osteoporosis.

Methods: We searched the literature, via PubMed, Embase, Cochrane Library, Web of Science and Google database to screen citations from inception to April 2018 for inclusion in this study. Only randomized controlled trials that compared teriparatide and bisphosphonates for reducing vertebral fracture risk in postmenopausal women with osteoporosis were included. Read More

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http://dx.doi.org/10.1016/j.ijsu.2019.03.004DOI Listing
March 2019
1 Read

Sex- and Sport-Specific Epidemiology of Cervical Spine Injuries Sustained During Sporting Activities.

World Neurosurg 2019 Feb 27;122:e540-e545. Epub 2018 Oct 27.

Department of Orthopaedics, Division of Spine Surgery, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

Background: Although several investigations have examined the epidemiology of cervical spine injuries in sports, few studies have analyzed the nationwide incidence and sex-specific epidemiology of cervical spine injuries.

Method: The National Electronic Injury Surveillance System database, which collects information on patients presenting to the emergency department at 100 hospitals across the United States, was queried for neck sprains and cervical fractures associated with sporting activities from 2000-2015.

Result: A total of 26,380 neck sprains and 1166 fractures were identified. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.097DOI Listing
February 2019
2 Reads

Nonmetallic posterior monosegmental cervical fusion of a dislocated C6/7 fracture in a 4-year-old girl : A case report.

Orthopade 2019 Mar 18. Epub 2019 Mar 18.

Spine Center, Department of Orthopaedic Surgery, Trauma Surgery and Division of Spinal Cord Injury, Ruprecht Karls University Heidelberg, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.

Purpose: Pediatric cervical spine injuries constitute approximately 1-2% of all pediatric trauma cases. Usually pediatric vertebral injuries appear as stable A type fractures, whereas B and C type injuries are relatively uncommon. In contrast to adults, the appropriate treatment strategy in children is still controversial and places spine surgeons in complex situations. Read More

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http://dx.doi.org/10.1007/s00132-019-03714-9DOI Listing

Monthly Intramuscular Neridronate for the Treatment of Postmenopausal Osteoporosis: Results of a 6-Year Prospective Italian Study.

Int J Endocrinol 2019 6;2019:9802827. Epub 2019 Feb 6.

CNR-Regione Toscana G Monasterio Foundation, Pisa, Italy.

Purpose: Oral bisphosphonates (BPs) are the most commonly used medications for osteoporosis (OP), but their poor gastrointestinal (GI) absorption and tolerance hamper compliance. Intramuscular (IM) neridronate (NE), an amino-BP, is an easy-to-administer, effective, and safe alternative to oral BPs. We assessed the 6-year effects of monthly IM NE on bone mineral density (BMD) and bone turnover biomarkers (BMs) in postmenopausal OP. Read More

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http://dx.doi.org/10.1155/2019/9802827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381585PMC
February 2019
1 Read

Risk Factors for Poor Prognosis of Cervical Spinal Cord Injury with Subaxial Cervical Spine Fracture-Dislocation After Surgical Treatment: A CONSORT Study.

Med Sci Monit 2019 Mar 16;25:1970-1975. Epub 2019 Mar 16.

Department of Orthopedics, Taizhou First People's Hospital, Taizhou, Zhejiang, China (mainland).

BACKGROUND The objective of the study was to identify risk factors for poor prognosis of cervical spinal cord injury (SCI) with subaxial cervical fracture-dislocation after surgical treatment. MATERIAL AND METHODS A total of 60 cervical SCI patients with subaxial cervical fracture-dislocation were primarily included in the study from April 2013 to April 2018. All the enrolled subjects received surgical treatment. Read More

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http://dx.doi.org/10.12659/MSM.915700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433098PMC

Predictive factors for the efficacy of denosumab in postmenopausal Japanese women with non-metastatic breast cancer receiving adjuvant aromatase inhibitors: a combined analysis of two prospective clinical trials.

J Bone Miner Metab 2019 Mar 13. Epub 2019 Mar 13.

Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

Aromatase inhibitors (AIs) are the gold standard therapy for breast cancer in postmenopausal women. AI suppresses the conversion of androgens to estrogens; however, this results in osteopenia, osteoporosis, and bone fracture, thus reducing the patient's quality of life. The use of adjuvant denosumab reduces the risk of clinical fractures in postmenopausal patients with breast cancer receiving AI. Read More

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http://dx.doi.org/10.1007/s00774-018-00985-8DOI Listing
March 2019
3 Reads

Management of Type II Odontoid Fractures in Adults.

Bull Hosp Jt Dis (2013) 2019 Mar;77(1):4-10

Fractures of the odontoid represent as much as 20% of cervical spine fractures in adults, and they are the most common spine fracture in patients over 80 years of age. Despite their prevalence, the management of these fractures remains highly controversial. In particular, there is much debate concerning the management of type II fractures, or fractures occurring about the waist of the odontoid. Read More

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[Advances in research of odontoid fractures in the elderly].

Zhonghua Wai Ke Za Zhi 2019 Mar;57(3):231-235

Department of Spinal Surgery, Zhengzhou Orthopaedic Hospital, Zhengzhou 450000, China.

Odontoid fractures constitute the most common cervical spine fracture in the population aged. The optimal management strategy for odontoid fractures remains controversial, especially in the elderly, because of the high morbidity and mortality with both conservative and operative intervention. This review discusses the management of odontoid fractures among the elderly, with a focus on the various treatment options and their outcomes. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2019.03.017DOI Listing

Efficacy and safety of denosumab compared to bisphosphonates in improving bone strength in postmenopausal osteoporosis: a systematic review.

Singapore Med J 2019 Mar 11. Epub 2019 Mar 11.

Department of Infectious Diseases, Singapore General Hospital, Singapore.

Introduction: Osteoporosis is the main cause of fractures among women after menopause. This study aimed to evaluate the efficacy and safety of denosumab compared to bisphosphonates in treating postmenopausal osteoporosis.

Methods: Databases including PubMed and the Cochrane Central Register of Controlled Trials were systematically searched for randomised controlled trials (RCTs) that directly compared denosumab and bisphosphonates. Read More

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http://dx.doi.org/10.11622/smedj.2019028DOI Listing
March 2019
3 Reads

The Characteristics and Cost of Le Fort Fractures: A Review of 519 Cases From a Nationwide Sample.

J Oral Maxillofac Surg 2019 Feb 13. Epub 2019 Feb 13.

Chairman and George Guttman Professor of Craniofacial Surgery, Section of Hospital Dentistry, Division of Oral and Maxillofacial Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center, Columbia University College of Dental Medicine, New York, NY.

Purpose: The aims were to report the characteristics of Le Fort fractures and to quantify the associated hospital costs.

Materials And Methods: From October 2015 to December 2016, the National Inpatient Sample was searched for patients admitted with a primary diagnosis of a Le Fort fracture. Predictor variables were drawn from demographic, admission, and injury characteristics. Read More

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http://dx.doi.org/10.1016/j.joms.2019.01.060DOI Listing
February 2019
2 Reads
1.280 Impact Factor

Multiple Vertebral Fractures Following Discontinuation Of Denosumab Treatment: Ten Clinical Cases Report.

Reumatol Clin 2019 Mar 4. Epub 2019 Mar 4.

Servicio de Reumatología, Hospital Universitario La Paz, Madrid, España.

Objectives: Analyse clinical and bone metabolism features in a case series of patients with multiple vertebral fractures after discontinuation of denosumab (DMab).

Methods: An observational descriptive study analysing data from ten patients with multiple vertebral fractures after DMab discontinuation that were admitted to our rheumatology department between 2015 and 2018.

Results: There were a total of 49 spontaneous fractures after an average of 6 DMab doses and 10. Read More

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http://dx.doi.org/10.1016/j.reuma.2018.11.002DOI Listing
March 2019
1 Read

Adherence to a Mediterranean Diet and Bone Mineral Density in Spanish Premenopausal Women.

Nutrients 2019 Mar 5;11(3). Epub 2019 Mar 5.

Metabolic Bone Disease Research Group, University of Extremadura, 10003 Cáceres, Spain.

The Mediterranean diet (MD) has been associated with an improvement in health and an increase in longevity. Certain components of a MD can play a role in the prevention of osteoporosis and/or hip fracture. We investigated the association between the degree of adherence to a MD and bone mineral density (BMD) measured in several bone areas in a population of Spanish premenopausal women. Read More

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https://www.mdpi.com/2072-6643/11/3/555
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http://dx.doi.org/10.3390/nu11030555DOI Listing
March 2019
5 Reads

[Influence of the trauma mechanism on cervical spine injuries].

Unfallchirurg 2019 Mar 6. Epub 2019 Mar 6.

Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland.

Background: The influence of trauma-related kinematics on the injury pattern of the cervical spine is currently not considered in the available classification systems, only the force vector. Whether the strength of the trauma has an additional influence on the number and complexity of the injuries and whether this can be classified, has not yet been finally investigated.

Objective: What influence do different kinematics apart from the traumatic force vector have on injuries of the cervical spine?

Material And Methods: Based on the AOSpine classification system for the upper and subaxial cervical spine, data from 134 trauma patients from a first level trauma center were retrospectively analyzed. Read More

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http://dx.doi.org/10.1007/s00113-019-0622-zDOI Listing

Complex spine deformities in young patients with severe osteogenesis imperfecta: current concepts review.

J Child Orthop 2019 Feb;13(1):22-32

Hacettepe University, Faculty of Medicine, Dept of Orthopaedics Ankara, Turkey.

The severity of osteogenesis imperfecta (OI), the associated reduced quality and quantity of collagen type I, the degree of bone fragility, ligamentous laxity, vertebral fractures and multilevel vertebral deformities all impair the mechanical integrity of the whole spinal architecture and relate to the high prevalence of progressive kyphoscoliotic deformities during growth. Bisphosphonate therapy may at best slow down curve progression but does not seem to lower the prevalence of deformities or the incidence of surgery. Brace treatment is problematic due to pre-existing chest wall deformities, stiffness of the curve and the brittleness of the ribs which limit transfer of corrective forces from the brace shell to the spine. Read More

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http://dx.doi.org/10.1302/1863-2548.13.180185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376432PMC
February 2019
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Urgent surgery for spinal instability or neurological impairment caused by spinal brown tumors occurring in the context of end-stage renal disease.

J Neurosurg Spine 2019 Mar 1:1-8. Epub 2019 Mar 1.

1Department of Orthopedic Oncology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai; and.

OBJECTIVESpinal instability or neurological impairment caused by spinal brown tumors (BTs) with end-stage renal disease (ESRD) is an acute condition that needs urgent surgery. There is not much published information on BTs of the mobile spine given the rarity of the disease, and the literature shows inconsistent treatment options and ambiguous follow-up information. The aim of the present study was to elucidate the clinical features, anesthesia management, and surgical treatment for this rare disease through long-term follow-up observations. Read More

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http://dx.doi.org/10.3171/2018.12.SPINE181044DOI Listing
March 2019
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Long-term Outcomes of Adolescent Anorexia Nervosa on Bone.

J Adolesc Health 2019 Mar 11;64(3):305-310. Epub 2018 Dec 11.

Department of Endocrinology, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; Discipline of Paediatrics & Child Health, University of Sydney, Sydney, New South Wales, Australia. Electronic address:

Purpose: Anorexia nervosa (AN) is a chronic and life-threatening eating disorder that can have a considerable negative impact on the growing skeleton. We hypothesized that the long-term impact on bone health may persist even after normalization of body weight.

Methods: 41 females (mean age 21. Read More

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http://dx.doi.org/10.1016/j.jadohealth.2018.07.025DOI Listing
March 2019
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Gender differences in bone mineral density in patients with sporadic primary hyperparathyroidism.

Endocrinol Diabetes Metab 2018 Oct 4;1(4):e00037. Epub 2018 Sep 4.

Department of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston Texas.

Context: Primary hyperparathyroidism reduces bone mineral density, which increases the risk of fracture.

Objective: To investigate differences in bone mineral density and clinical characteristics after parathyroidectomy between men and women (premenopausal and postmenopausal) with sporadic primary hyperparathyroidism.

Design: This is a retrospective study of adult patients who underwent parathyroidectomy in a tertiary referral center from 1990 to 2013. Read More

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http://dx.doi.org/10.1002/edm2.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354761PMC
October 2018
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Facial Fractures as a Result of Falls in the Elderly: Concomitant Injuries and Management Strategies.

Craniomaxillofac Trauma Reconstr 2019 Mar 17;12(1):45-53. Epub 2018 May 17.

Department of Plastic Surgery, Rutgers-New Jersey Medical School, Newark, New Jersey.

Mechanical falls are a common cause of facial trauma in the elderly population. It has been shown that the likelihood of sustaining a facial fracture due to a fall or activities of daily life significantly increases with age. Craniomaxillofacial fractures are most common during the first three decades of life; however, elderly patients more frequently require lengthy hospital stays and surgical intervention, and have shown increased complication rates compared with younger patients. Read More

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http://dx.doi.org/10.1055/s-0038-1642034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391279PMC
March 2019
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Predictors of mortality in the elderly patient with a fracture of the odontoid process.

Bone Joint J 2019 Mar;101-B(3):253-259

Department of Spinal Surgery, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.

Aims: Fracture of the odontoid process (OP) in the elderly is associated with mortality rates similar to those of hip fracture. The aim of this study was to identify variables that predict mortality in patients with a fracture of the OP, and to assess whether established hip fracture scoring systems such as the Nottingham Hip Fracture Score (NHFS) or Sernbo Score might also be used as predictors of mortality in these patients.

Patients And Methods: We conducted a retrospective review of patients aged 65 and over with an acute fracture of the OP from two hospitals. Read More

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http://dx.doi.org/10.1302/0301-620X.101B3.BJJ-2018-1004.R1DOI Listing
March 2019
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Traumatic Atlantoaxial Lateral Subluxation With Chronic Type II Odontoid Fracture: A Case Report.

Int J Spine Surg 2019 Jan 22;13(1):79-83. Epub 2019 Feb 22.

Department of Orthopaedic Surgery, University of California Irvine Medical Center, Orange, California.

Background: We report a case of an elderly patient who was diagnosed with lateral atlantoaxial subluxation with type II odontoid fracture, an extremely uncommon upper cervical spine injury that has not been previously reported in the literature to the knowledge of the authors.

Methods: An 87-year-old male reported to the emergency room following a syncopal episode after sustaining a fall. He complained of dizziness, fatigue, disruption of vision and audition, and worsening neck pain. Read More

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http://dx.doi.org/10.14444/6010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383461PMC
January 2019

Traumatic Fracture of the Pediatric Cervical Spine: Etiology, Epidemiology, Concurrent Injuries, and an Analysis of Perioperative Outcomes Using the Kids' Inpatient Database.

Int J Spine Surg 2019 Jan 22;13(1):68-78. Epub 2019 Feb 22.

Division of Spinal Surgery, Departments of Orthopaedic and Neurological Surgery, Hospital for Joint Diseases at NYU Langone Medical Center, NYU School of Medicine, New York, New York.

Background: The study aimed to characterize trends in incidence, etiology, fracture types, surgical procedures, complications, and concurrent injuries associated with traumatic pediatric cervical fracture using a nationwide database.

Methods: The Kids' Inpatient Database (KID) was queried. Trauma cases from 2003 to 2012 were identified, and cervical fracture patients were isolated. Read More

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http://dx.doi.org/10.14444/6009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383458PMC
January 2019
7 Reads

Risk Factors for Low Bone Density in Inflammatory Bowel Disease: Use of Glucocorticoids, Low Body Mass Index, and Smoking.

Dig Dis 2019 21;37(4):284-290. Epub 2019 Feb 21.

Department of Endocrinology, Rambam Health Care Centre, Haifa, Israel.

Background: Inflammatory bowel disease (IBD) patients are reported to have lower bone density compared to healthy controls. There is limited consensus regarding factors affecting bone density among these patients. Our aim, therefore, was to determine clinical and genetic variables that contribute to lower bone mineral density (BMD) in IBD patients. Read More

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http://dx.doi.org/10.1159/000496935DOI Listing
February 2019
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Risk Factors Associated with 30-Day Mortality After Open Reduction and Internal Fixation of Vertebral Fractures.

World Neurosurg 2019 Feb 18. Epub 2019 Feb 18.

Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:

Objective: Few studies have examined the outcomes of open reduction and internal fixation of vertebral fractures. The purpose of this study was to determine patient-related and surgery-related risk factors associated with 30-day postoperative mortality after open reduction and internal fixation (ORIF) of cervical, thoracic, and lumbar vertebral fractures.

Methods: This was a retrospective cohort study of data from the 2010-2014 ACS-NSQIP database. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.247DOI Listing
February 2019

Performing the screw fixation from C3 to odontoid process in a patient with Klippel-Feil syndrome and type II odontoid fracture.

J Craniovertebr Junction Spine 2018 Oct-Dec;9(4):277-279

Department of Neurosurgery, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

A 56-year-old female patient was admitted with a history of pain during neck movements after cervical injury. Computerized tomography scan revealed type II odontoid fracture and fusion anomaly between C2 and C3 vertebrae. At surgery, the anteroinferior part of C2 vertebra corpus could not be reached; therefore, transodontoid screw was advanced from C3 vertebra toward odontoid process. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_54_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364369PMC
February 2019