10,001 results match your criteria Fracture Cervical Spine


Surgical prevention of femoral neck fractures in elderly osteoporotic patients: a randomised controlled study on the prevention nail system device.

Hip Int 2018 Nov;28(2_suppl):78-83

1 I.R.C.C.S. - Istituto Ortopedico Rizzoli, Bologna, Italy.

Introduction:: Hip fractures represent an enormous challenge for our health care system. The aim of this randomised controlled trial was to assess both efficacy and safety of a novel device called Prevention Nail System (PNS) and developed for the surgical prevention of a contralateral femoral neck fracture (FNF) in elderly osteoporotic patients.

Methods:: Primary outcome was to evaluate, in patients suffering from osteoporotic FNF, the effectiveness of PNS in reducing the incidence of a contralateral hip fracture. Read More

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http://dx.doi.org/10.1177/1120700018813207DOI Listing
November 2018

Fracture patterns in patients with multiple fractures: the probability of multiple fractures and the most frequently associated regions.

Eur J Trauma Emerg Surg 2019 Feb 12. Epub 2019 Feb 12.

St. Vincent Hospital-Metabolic Bone Diseases Unit, The VINFORCE Study Group, Vienna, Austria.

Introduction: Multiple fractures are of high clinical relevance, as a significant increase in mortality rate has been described. The purpose of this study was to evaluate differences in age and gender distribution in multiple fractures dependent on severity of trauma. Furthermore, affected anatomic regions and frequently associated fracture regions were investigated. Read More

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http://dx.doi.org/10.1007/s00068-019-01087-4DOI Listing
February 2019

High prevalence of vertebral fractures and low trabecular bone score in patients with fragility fractures: A cross-sectional sub-study of NoFRACT.

Bone 2019 Feb 8;122:14-21. Epub 2019 Feb 8.

Department of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.

Purpose: Norway has among the highest incidence rates of fractures in the world. Vertebral fracture assessment (VFA) and trabecular bone score (TBS) provide information about fracture risk, but their importance have not been studied in Norwegian patients with fragility fractures. The objectives of this study were to examine the clinical characteristics of a cohort of women and men with fragility fractures, their prevalence of vertebral fractures using VFA and prevalence of low TBS, and explore the differences between the sexes and patients with and without vertebral fractures. Read More

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http://dx.doi.org/10.1016/j.bone.2019.02.008DOI Listing
February 2019
1 Read

School Nurses on the Front Lines of Medicine: Emergencies Associated With Sport and Physical Activities: Part 1.

NASN Sch Nurse 2019 Feb 9:1942602X18819223. Epub 2019 Feb 9.

Professor, Departments of Emergency Medicine and Pediatrics, Penn State College of Medicine.

Illness and injury associated with sport and physical activities may occur in the school setting. Although most sport-related illness and injury in students are considered minor emergencies, life- and limb-threatening illnesses or injuries may occur, such as sudden cardiac arrest, heat stroke, status asthmaticus, catastrophic brain or cervical spine injuries, hypoglycemia, blunt chest/abdominal injuries, or extremity fractures requiring surgery. It is important for the school nurse to recognize potential life- and limb-threatening emergencies associated with sport and physical activity, to initiate stabilization of the student with life- and limb-threatening symptoms, and to triage these students to an appropriate level of care (back to the classroom, home with their guardian with follow up at their primary healthcare provider's office, or directly to the closest emergency department via emergency medical services). Read More

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http://dx.doi.org/10.1177/1942602X18819223DOI Listing
February 2019
2 Reads

Calciotropic Hormones and the Prevalence of Vertebral Fractures in Chinese Postmenopausal Women with Vitamin D Insufficiency: Peking Vertebral Fracture Study.

Calcif Tissue Int 2019 Feb 8. Epub 2019 Feb 8.

Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, National Commission of Health, Chinese Academy of Medical Science, No. 1 Shuaifuyuan, Wangfujing Street, Dongcheng District, Beijing, 100730, China.

This case-control study aimed to examine the effect of high serum parathyroid hormone (PTH) level, especially the effect of secondary hyperparathyroidism (SHPT) related to hypovitaminosis D, on bone metabolism and bone phenotypes. We included a total of 830 Chinese postmenopausal women aged ≥ 50 years with serum 25-hydroxyvitamin D (25(OH)D) level < 30 ng/ml, among whom 415 women had prevalent vertebral fractures (VFs) and others were age-matched controls. We measured serum levels of 25(OH)D, PTH and bone turnover markers (BTMs), which included C-terminal telopeptide of type I collagen (β-CTX), N-aminoterminal prepeptide of type I procollagen (P1NP) and osteocalcin (OC). Read More

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http://dx.doi.org/10.1007/s00223-019-00531-2DOI Listing
February 2019
1 Read

Transpedicular lag screw placement in traumatic cervical spondylolisthesis: Case report and systematic review of the literature.

J Clin Neurosci 2019 Feb 5. Epub 2019 Feb 5.

Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address:

Traumatic spondylolisthesis of C2-C3 is an unstable fracture. Posterior fixation techniques can be employed with intraoperative navigation, however this tool is not available to all spine surgeons. Furthermore, the evidence for posterior surgical stabilization of C2, while adhering to motion preservation principles is currently unknown. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.01.036DOI Listing
February 2019

The Y-shaped trabecular bone structure in the odontoid process of the axis: a CT scan study in 54 healthy subjects and biomechanical considerations.

J Neurosurg Spine 2019 Feb 1:1-8. Epub 2019 Feb 1.

4Professional Dental Studio A.P., Prato, Italy.

OBJECTIVEOdontoid process fractures are very common in both young and geriatric patients. The axial trabecular architecture of the dens appears to be crucial for physiological and biomechanical function of the C1-2 joint. The aim of this study is to demonstrate the presence of a Y-shaped trabecular structure of the dens on axial CT and to describe its anatomical and biomechanical implications. Read More

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http://dx.doi.org/10.3171/2018.9.SPINE18396DOI Listing
February 2019

Cervical and thoracic spine injury in pediatric motor vehicle crash passengers.

Traffic Inj Prev 2019 Feb 4:1-9. Epub 2019 Feb 4.

d Nationwide Children's Center for Injury Research and Policy , Columbus , Ohio.

Objective: Motor vehicle occupants aged 8 to 12 years are in transition, in terms of both restraint use (booster seat or vehicle belt) and anatomical development. Rear-seated occupants in this age group are more likely to be inappropriately restrained than other age groups, increasing their vulnerability to spinal injury. The skeletal anatomy of an 8- to 12-year-old child is also in developmental transition, resulting in spinal injury patterns that are unique to this age group. Read More

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http://dx.doi.org/10.1080/15389588.2018.1529412DOI Listing
February 2019
1 Read

Neurological disability among adults following traumatic spinal fractures in Saudi Arabia: a retrospective single-center medical record review.

Ann Saudi Med 2019 Jan-Feb;39(1):8-12

Dr. Suhail Saad AlAssiri, Department of Orthopedic Surgery,, National Guard Hospital,, King Abdulaziz Medical City,, Riyadh 11662, Saudi Arabia, T: +9966563456700, suhailasiri@ gmail.com, ORCID: http://orcid. org/0000-0001-7119-1201.

Background: A traumatic spinal fracture (TSF) is a serious condition that has a tremendous impact on patients and their families. Understanding the causes and patterns of TSF is critical in developing prevention programs.

Objectives: Identify causes and patterns of TSF and explore predictors of neurological disability in Saudi Arabia. Read More

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http://dx.doi.org/10.5144/0256-4947.2019.8DOI Listing
February 2019
0.705 Impact Factor

Postmenopausal osteoporotic fracture-associated COLIA1 variant impacts bone accretion in girls.

Bone 2019 Jan 31;121:221-226. Epub 2019 Jan 31.

Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, United States of America; Department of Genetics, University of Pennsylvania, Philadelphia, PA, United States of America; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, United States of America. Electronic address:

Over the past two decades, a low frequency variant (rs1800012) within the first intron of the type I collagen alpha 1 (COLIA1) gene has been implicated in lower areal BMD (aBMD) and increased risk of osteoporotic fracture. This association is particularly strong in postmenopausal women, in whom net bone loss arises in the context of high bone turnover. High bone turnover also accompanies childhood linear growth; however, the role of rs1800012 in this stage of net bone accretion is less well understood. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S87563282193003
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http://dx.doi.org/10.1016/j.bone.2019.01.026DOI Listing
January 2019
3 Reads

Inter- and intra-rater reliability of vertebral fracture classifications in the Swedish fracture register.

World J Orthop 2019 Jan 18;10(1):14-22. Epub 2019 Jan 18.

Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm SE-14186, Sweden.

Aim: To investigate the inter- and intra-rater reliability of the vertebral fracture classifications used in the Swedish fracture register.

Methods: Radiological images of consecutive patients with cervical spine fractures ( = 50) were classified by 5 raters with different experience levels at two occasions. An identical process was performed with thoracolumbar fractures ( = 50). Read More

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http://dx.doi.org/10.5312/wjo.v10.i1.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354108PMC
January 2019

Cervical Fracture With Posterior Ligamentous Injury While Skydiving.

J Orthop Sports Phys Ther 2019 Feb;49(2):113

A 46-year-old male soldier reported to an emergency department with severe acute neck pain immediately following a hyperflexion injury during recreational skydiving. He was evaluated in the emergency department, including radiographs, and released with a diagnosis of "acute neck strain." After presenting with continued neck pain, he was sent for consultation with a physical therapist. Read More

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https://www.jospt.org/doi/10.2519/jospt.2019.8360
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http://dx.doi.org/10.2519/jospt.2019.8360DOI Listing
February 2019
2 Reads

[A mini-incision on the anterior hip for pediatric femur neck fractures of type Delbet Ⅱ].

Zhonghua Wai Ke Za Zhi 2019 Feb;57(2):129-133

Department of Pediatric Orthopaedic, Children's Hospital, Nanjing Medical University, Nanjing 210019, China.

To investigate the early clinical outcomes of hip anterior short incision and open reduction and internal fixation for the treatment of children with Delbet Ⅱ femoral neck fracture. A retrospective analysis of 12 children with DelbetⅡ femoral neck fractures was performed with the anterior short incision approach at Department of Pediatric Orthopaedic, Children's Hospital, Nanjing Medical University from January 2014 to August 2016. There were 7 males and 5 females including 8 cases at left side and 4 cases at right side,aged (11. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2019.02.011DOI Listing
February 2019
4 Reads

Abaloparatide: A new pharmacological option for osteoporosis.

Am J Health Syst Pharm 2019 Jan;76(3):130-135

Department of Pharmacy Practice, Presbyterian College School of Pharmacy, Clinton, SC.

Purpose: The efficacy and safety of abaloparatide, a parathyroid hormone-related protein analog for the treatment of osteoporosis in postmenopausal women at high fracture risk, is reviewed.

Summary: A MEDLINE search was conducted for full text English-language articles, using the terms abaloparatide, parathyroid hormone, and osteoporosis. Published articles pertinent to the short- and long-term efficacy and safety of abaloparatide among postmenopausal women with osteoporosis were reviewed and summarized. Read More

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https://academic.oup.com/ajhp/article/76/3/130/5290437
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http://dx.doi.org/10.1093/ajhp/zxy022DOI Listing
January 2019
4 Reads

Medical and surgical management of acute spinal injury during pregnancy: A case series in a third-world country.

Surg Neurol Int 2018 24;9:258. Epub 2018 Dec 24.

Department of Neurosurgery, Juha Hernesniemi International Neurosurgery Center, Henan Provincial People's Hospital, 7 Weiwu Road, Zhengzhou, China.

Background: There is scant literature describing the management of acute spinal injury in pregnant patients. Here, we report our experience with five cases of pregnant patients including three females who suffered acute traumatic spinal cord injuries (SCIs).

Methods: This retrospective study evaluated five pregnant women presenting with traumatic spinal injuries over a 16-month period. Read More

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http://dx.doi.org/10.4103/sni.sni_380_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322169PMC
December 2018
1 Read

Influence of Smoking on Bone Mineral Density in Elderly Men.

Int J Prev Med 2018 24;9:111. Epub 2018 Dec 24.

Department of Internal Medicine, Rohani Hospital, Babol University of Medical Sciences, Babol, Iran.

Background: Smoking has deleterious effects on bone mass and is associated with the subsequent development of osteoporosis, particularly in elderly participants. The purpose of this study was to determine the influence of smoking in the elderly male smokers.

Methods: All male participants aged 60 years and older of the Amirkola cohort who performed bone densitometry entered the study. Read More

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http://dx.doi.org/10.4103/ijpvm.IJPVM_234_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326023PMC
December 2018
1 Read

Development and validation of a new simplified anatomic trauma mortality score.

Injury 2019 Jan 17. Epub 2019 Jan 17.

Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Malaysia. Electronic address:

Background: Most trauma mortality prediction scores are complex in nature. GAP (Glasgow Coma Scale, Age, Systolic blood pressure) and mGAP (mechanism, Glasgow Coma Scale, Age, Systolic blood pressure) scores are relatively simple scoring tools. However, these scores were not validated in low and middle income countries including Malaysia and its accuracies are influenced by the fluctuating physiologic parameters. Read More

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http://dx.doi.org/10.1016/j.injury.2019.01.027DOI Listing
January 2019

Bilateral vertebral artery occlusion after cervical spine fracture dislocation.

World Neurosurg 2019 Jan 23. Epub 2019 Jan 23.

Department of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California. Electronic address:

Vertebral artery injury is known to potentially occur in conjunction with blunt cervical spine trauma. Rarely, these injuries present bilaterally as complete occlusions. Twelve cases of bilateral vertebral artery occlusions after closed cervical spine trauma have been reported in the literature, nearly all of which demonstrated signs and symptoms of vertebrobasilar insufficiency and ischemia. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.033DOI Listing
January 2019
1 Read

Delayed surgery for displaced fracture of the anatomic neck and spine of the scapula: a case report and literature review.

JSES Open Access 2018 Oct 14;2(3):169-173. Epub 2018 Jul 14.

Department of Orthopedic Surgery, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jses.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334870PMC
October 2018

C2-C3 spinal fracture subluxation with ligamentous and vascular injury: a case report and review of management.

Spinal Cord Ser Cases 2019 16;5. Epub 2019 Jan 16.

1Department of Neurosurgery, Medstar Georgetown University Hospital, 3800 Reservoir Rd., PHC 7, Washington, DC 20007 USA.

Introduction: Spinal cord injury is one of the leading causes of paralysis and permanent morbidity. High cervical spine injuries, in particular, have the potential to be fatal and debilitating due to injury to multiple components, including but not limited to, discoligamentous disruption, vascular insult and spinal cord injury. To date, no unifying algorithm exists making it challenging to guide treatment decisions. Read More

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http://dx.doi.org/10.1038/s41394-019-0150-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335400PMC
January 2019
11 Reads

Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials.

J Bone Miner Res 2019 Jan 23. Epub 2019 Jan 23.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.

Meta-analyses conducted >15 years ago reported that improvements in bone mineral density (BMD) were associated with reduction in vertebral and nonvertebral fractures in osteoporosis trials. Numerous studies have been conducted since then, incorporating new therapies with different mechanisms of action and enrolling many more subjects. To extend these prior analyses, we conducted a meta-regression of 38 placebo-controlled trials of 19 therapeutic agents to determine the association between improvements in BMD and reductions in fracture risk. Read More

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http://dx.doi.org/10.1002/jbmr.3641DOI Listing
January 2019
1 Read

Type II odontoid fracture in elderly patients treated conservatively: is fracture healing the goal?

Eur Spine J 2019 Jan 23. Epub 2019 Jan 23.

Neurosurgery Division, University Hospital S.Anna, Viale Aldo Moro 8, 44121, Cona di Ferrara, Italy.

Purpose: Analysis of functional outcome of elderly patients with type II odontoid fractures treated conservatively in relation to their radiological outcome.

Methods: A total of 50 geriatric patients with type II odontoid fractures were treated with Aspen/Vista collars. On admission, each patient was assessed assigning ASA score, modified Rankin Scale (mRS-pre) and Charlson Comorbidity Index (CCI). Read More

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http://dx.doi.org/10.1007/s00586-019-05898-2DOI Listing
January 2019
3 Reads

Evaluating the Role of a Neurosurgery Consultation in Management of Pediatric Isolated Linear Skull Fractures.

Pediatr Neurosurg 2019 Jan 23:1-7. Epub 2019 Jan 23.

Department of Neurosurgery, Virginia Commonwealth University Health System, Richmond, Virginia, USA.

Background: The purpose of this study was to determine if a pediatric neurosurgical consultation for isolated linear skull fractures (ILSF) in pediatric patients with Glasgow Coma Scale (GCS) scores of ≥14 changed their management.

Methods: A 10-year retrospective chart review at a Level 1 Pediatric Trauma Center was performed. Exclusion criteria were age > 18 years, open, depressed, or skull base fractures, pneumocephalus, poly-trauma, any hemorrhage (intraparenchymal, epidural, subdural, subarachnoid), cervical spine fractures, penetrating head trauma, and initial GCS scores ≤13. Read More

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https://www.karger.com/Article/FullText/495792
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http://dx.doi.org/10.1159/000495792DOI Listing
January 2019
4 Reads

Cervical spinal cord injury after blunt assault: Just a pain in the neck?

Am J Surg 2018 Jun 23. Epub 2018 Jun 23.

Division of Trauma, Emergency Surgery & Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, 165 Cambridge Street Suite 810, Boston, MA, 02114, USA. Electronic address:

Background: We aimed to determine the incidence, risk factors, and outcomes of cervical spinal cord injury (CSCI) after blunt assault.

Methods: The ACS National Trauma Data Bank (NTDB) 2012 Research Data Set was used to identify victims of blunt assault using the ICD-9 E-codes 960.0, 968. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2018.06.022DOI Listing
June 2018
1 Read

Functional Outcome of Elderly Patients Treated for Odontoid Fracture: A Multicenter Study.

Spine (Phila Pa 1976) 2019 Jan 14. Epub 2019 Jan 14.

Neurosurgery Division, "M. Bufalini" Hospital, Cesena, Italy.

MINI: Functional outcome of elderly patients treated for odontoid fracture is strictly related to their pre-injury level of function and comorbidity. Compared with conservative external immobilizations, surgery revealed no advantages in the elderly in terms of functional outcome.

Study Design: Retrospective multicenter study. Read More

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http://Insights.ovid.com/crossref?an=00007632-900000000-9474
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http://dx.doi.org/10.1097/BRS.0000000000002982DOI Listing
January 2019
9 Reads

Variations in treatment of C1 fractures by time, age, and geographic region in the United States: An analysis of 985 patients.

Orthop Rev (Pavia) 2018 Dec 6;10(4):7834. Epub 2018 Dec 6.

Department of Orthopedic Surgery, Emory University School of Medicine, Atlanta, GA.

The purpose of this investigation was to evaluate the variations in the treatment of C1 fractures over time, by age group, and by geographic region using a nationwide database. The Nationwide Emergency Department Sample (NEDS) database was queried to identify patients ≥18 years who sustained C1 fracture from 2006-2012. Patients were filtered based on the intervention they received: collar, halo, or surgery. Read More

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http://dx.doi.org/10.4081/or.2018.7834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315308PMC
December 2018
1 Read

Lower baseline value and greater decline in BMD as independent risk factors for mortality in community dwelling elderly.

Bone 2019 Jan 17;121:204-211. Epub 2019 Jan 17.

Department of Internal Medicine, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Seongnam, Republic of Korea. Electronic address:

Skeleton plays diverse roles via crosstalk between others, thus it is conceivable that lower BMD per se may reflect negative influences on health status and threats to life independent of fracture events. We investigated investigate the association between BMD and mortality, and to examine whether the rate of bone loss can predict future mortality in an elderly population. This study was conducted as a part of the Korean Longitudinal Study on Health and Aging, a community-based prospective study of Korean people aged 65 years and older that began in 2005. Read More

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http://dx.doi.org/10.1016/j.bone.2019.01.017DOI Listing
January 2019
3 Reads

Strong binding active constituents of phytochemical to BMPR1A promote bone regeneration: In vitro, in silico docking, and in vivo studies.

J Cell Physiol 2019 Jan 17. Epub 2019 Jan 17.

Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.

Two of the most problematic orthopedic and neurosurgeon visits are associated with spine and craniofacial fractures. Therefore, more attention needs to be paid to finding a medicine to repair these fractures. Amongst the most mysterious herbs, Aloe vera stands out. Read More

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http://dx.doi.org/10.1002/jcp.28121DOI Listing
January 2019

A pathological toe fracture as the first presentation of cervical cancer: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e14190

Department of Orthopedic Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital.

Rationale: Cervical cancer is one of the most common gynecologic malignancies worldwide, and it spreads mainly through direct extension. Distinct metastases are less common and usually spread to distant lymph nodes, lungs, and bones. Bone metastases from cervical cancer are most commonly observed in the pelvis and spine. Read More

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http://dx.doi.org/10.1097/MD.0000000000014190DOI Listing
January 2019
1 Read

Clinical and radiological outcomes of a cervical cage with integrated fixation.

Medicine (Baltimore) 2019 Jan;98(3):e14097

Clinical Affairs Department, Zimmer Biomet Spine, Troyes, France.

Cervical cages with integrated fixation have been increasingly used in anterior cervical discectomy and fusion (ACDF) to avoid complications associated with anterior cervical plates. The purpose of this paper is to provide 2-year follow-up results of a prospective study after implantation of a cervical cage with an integrated fixation system.This was a prospective multicenter outcome study of 90 patients who underwent ACDF with a cage with integrated fixation. Read More

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http://dx.doi.org/10.1097/MD.0000000000014097DOI Listing
January 2019
8 Reads

[A strategy of combining posterior occipitocervical angle with occipital-C angle for adjustment of occipitocervical fixation angle in posterior instrumented occipitocervical fusion].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Jan;33(1):35-40

Operating Room, West China Hospital, Sichuan University, Chengdu Sichuan, 610041,

Objective: To assess the application and the effectiveness of a strategy of combining posterior occipitocervical angle (POCA) with occipital-C (O-C ) angle for adjustment of occipitocervical fixation angle in posterior instrumented occipitocervical fusion.

Methods: The clinical data of 22 patients undergoing posterior instrumented occipitocervical fusions between March 2013 and January 2016 were retrospectively analysed, and all patients were performed by using a strategy combining with POCA and O-C angle for adjustment of occipitocervical fixation angle. All patients suffered from occipitocervical instability, including 7 males and 15 females with an average age of 44. Read More

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http://www.rrsurg.com/article/10.7507/1002-1892.201807115
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http://dx.doi.org/10.7507/1002-1892.201807115DOI Listing
January 2019
5 Reads

Circulating miR-103a-3p and miR-660-5p are associated with bone parameters in patients with controlled acromegaly.

Endocr Connect 2019 Jan;8(1):39-49

Endocrinology/Medicine Department, Hospital Sant Pau, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), IIB-Sant Pau, ISCIII and Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.

Background Biochemical control of GH/IGF-I excess in acromegaly (ACRO) is associated with persistent impairment of trabecular microstructure leading to increased risk of vertebral fractures. Circulating miRNAs modulate the activity of osteoblasts and osteoclasts, and may be potential biomarkers of osteoporosis. Aims Identify differentially expressed miRNAs in the serum of patients with controlled ACRO vs controls and correlate miRNA levels with both biochemical and structural bone parameters. Read More

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http://dx.doi.org/10.1530/EC-18-0482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330718PMC
January 2019
2 Reads

Spinal fractures incurred by a fall from standing height.

Clin Neurol Neurosurg 2019 Feb 7;177:106-113. Epub 2019 Jan 7.

Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, United Kingdom; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Tremona Road, Southampton, SO16 6YD, United Kingdom. Electronic address:

Objective: Falls from standing are common, particularly amongst the aging population, due to declining mobility, proprioception and vision. They are often complicated by fragility fractures, including vertebral fractures, that are associated with significant morbidity and may represent a pre-terminal condition with high one-year mortality rates.

Patients And Methods: A retrospective review of the Trauma Audit and Research Network database for a major trauma centre was conducted for all patients admitted between January 2011 and December 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03038467193000
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http://dx.doi.org/10.1016/j.clineuro.2019.01.005DOI Listing
February 2019
6 Reads

Treating fractures in upper limb gunshot injuries: The Cape Town experience.

Orthop Traumatol Surg Res 2019 Jan 9. Epub 2019 Jan 9.

Groote Schuur Hospital, Cape Town, South Africa.

Background: Upper extremity gunshot fractures are generally treated conservatively or surgically using open reduction and internal fixation (ORIF), intramedullary nails (IM) or external fixators. However, there is no gold standard for the management of these complex, multi-fragmentary upper extremity fractures. The aim was to describe and identify the injury patterns, management, complications and associated risk factors for upper extremity gunshot fractures. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18770568183035
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http://dx.doi.org/10.1016/j.otsr.2018.11.002DOI Listing
January 2019
3 Reads

Early ventral surgical treatment without traction of acute traumatic subaxial cervical spine injuries.

Surg Neurol Int 2018 13;9:254. Epub 2018 Dec 13.

Department of Neurosurgery, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mail Stop 3021, Kansas City, KS, U.S.A.

Background: Spinal cord decompression after cervical spinal cord injury (SCI) is the standard of care. However, there is a lack of consensus regarding the optimal management of these injuries, including the role of traction and timing of surgery. Here, we report the safety/efficacy of ventral surgery without preoperative traction for intraoperative fracture reduction following acute cervical SCI. Read More

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http://dx.doi.org/10.4103/sni.sni_352_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302551PMC
December 2018
3 Reads

Chronic hyponatremia and association with osteoporosis among a large racially/ethnically diverse population.

Osteoporos Int 2019 Jan 11. Epub 2019 Jan 11.

Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA.

Chronic hyponatremia may contribute to decreased bone density. We studied 341,003 men and women who underwent DXA testing and observed that individuals with chronic hyponatremia (sodium < 135 mEq/L) had an 11% greater likelihood of having osteoporosis. There was a dose-dependent effect with lower sodium and stronger association with osteoporosis. Read More

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http://link.springer.com/10.1007/s00198-018-04832-4
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http://dx.doi.org/10.1007/s00198-018-04832-4DOI Listing
January 2019
2 Reads

Treatment of Adhesive Capsulitis of the Shoulder.

J Am Acad Orthop Surg 2019 Jan 2. Epub 2019 Jan 2.

From the Columbia University Medical Center, Department of Orthopedics, Center for Shoulder Elbow and Sports Medicine, New York, NY.

Adhesive capsulitis presents clinically as limited, active and passive range of motion caused by the formation of adhesions of the glenohumeral joint capsule. Radiographically, it is thickening of the capsule and rotator interval. The pathology of the disease, and its classification, relates to inflammation and formation of extensive scar tissue. Read More

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http://dx.doi.org/10.5435/JAAOS-D-17-00606DOI Listing
January 2019
3 Reads

The long-term impact of very preterm birth on adult bone mineral density.

Bone Rep 2019 Jun 12;10:100189. Epub 2018 Dec 12.

Research Center, Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte-Ste-Catherine, Montreal, Quebec H3T 1C5, Canada.

Introduction: Preterm infants are at increased risk of osteopenia of prematurity due to insufficient bone mineral accretion. Data on long term effects of prematurity on bone health are conflicting. This study aimed to compare bone mineral density (BMD) in young adults born very preterm and full-term controls and to examine factors associated with long-term bone health. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23521872183005
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http://dx.doi.org/10.1016/j.bonr.2018.100189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319299PMC
June 2019
7 Reads

Obesity, bone density relative to body weight and prevalent vertebral fracture at age 62 years: the Newcastle thousand families study.

Osteoporos Int 2019 Jan 8. Epub 2019 Jan 8.

Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.

Obesity increases the likelihood of prevalent vertebral fracture (VF) in men and women at age 62 years. The higher absolute bone mineral density (BMD) observed in obese individuals is disproportionate to body weight, and this may partly explain the greater prevalence of VF in this group.

Introduction: Obesity is a global epidemic, and there remains uncertainty over the effect of obesity on skeletal health, particularly in the context of osteoporosis. Read More

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http://link.springer.com/10.1007/s00198-018-04817-3
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http://dx.doi.org/10.1007/s00198-018-04817-3DOI Listing
January 2019
5 Reads

Bone mineral density evolution and incidence of fractures in a cohort of patients with primary hyperparathyroidism treated with parathyroid surgery vs active surveillance during 6 years of follow-up.

Endocrinol Diabetes Nutr 2019 Jan 6;66(1):41-48. Epub 2018 Jul 6.

Servicio de Endocrinología, Hospital Universitario Marqués de Valdecilla, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, , Santander (Cantabria), España.

Introduction: The need for parathyroidectomy to treat asymptomatic patients with primary hyperparathyroidism is controversial. The aim of this study was to assess the impact of parathyroidectomy vs. surveillance on skeletal outcomes such as bone mineral density (BMD) and incident fractures. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25300164183013
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http://dx.doi.org/10.1016/j.endinu.2018.05.010DOI Listing
January 2019
8 Reads

Learning Curve in Surgical Treatment of Odontoid Fixation for a Series of Type II C2 Fractures.

Acta Neurochir Suppl 2019 ;125:325-327

Neurosurgical Clinic, AOUP "Paolo Giaccone", PostGraduate Residency Program in Neurologic Surgery, Department of Experimental Biomedicine and Clinical Neurosciences, School of Medicine, University of Palermo, Palermo, Italy.

The craniovertebral junction (CVJ) is a complex anatomical area upon which most of the motion of the upper cervical spine depends [1]. Because of its unique range of motion, the CVJ is subject to several types of traumatic injury; it has been shown that odontoid fractures are the most common ones in the general population and are the most common isolated spinal fractures [2]. Accounting for up to 18% of all cervical fractures, odontoid fractures are the most common ones in elderly patients [3], in whom they account for up to 60% of spinal cord injuries [4]. Read More

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http://dx.doi.org/10.1007/978-3-319-62515-7_47DOI Listing
January 2019
2 Reads

Analysis of the Frequency and Mechanism of Injury to Warfighters in the Under-body Blast Environment.

Stapp Car Crash J 2018 Nov;62:489-513

Survivability/Lethality Analysis Directorate (SLAD).

During Operation Iraqi Freedom and Operation Enduring Freedom, improvised explosive devices were used strategically and with increasing frequency. To effectively design countermeasures for this environment, the Department of Defense identified the need for an under-body blast-specific Warrior Injury Assessment Manikin (WIAMan). To help with this design, information on Warfighter injuries in mounted under-body blast attacks was obtained from the Joint Trauma Analysis and Prevention of Injury in Combat program through their Request for Information interface. Read More

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November 2018
6 Reads

Management challenges of traumatic spondylolisthesis of the Axis with an unusual C2-C3 posterior subluxation in a paediatric patient: case report and literature review.

Afr Health Sci 2018 Jun;18(2):458-467

Department of Orthopaedic Surgery, Groote Schuur Hospital, Cape Town, South Africa.

Introduction: Paediatric cervical spine injuries are uncommon. Traumatic spondylolisthesis of the axis (TSA) is commonly encountered in the trauma setting. The management of TSA may be surgical or non-surgical. Read More

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http://dx.doi.org/10.4314/ahs.v18i2.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306986PMC
June 2018
1 Read

Blunt Thoracolumbar-Spine Trauma Evaluation in the Emergency Department: A Meta-Analysis of Diagnostic Accuracy for History, Physical Examination, and Imaging.

J Emerg Med 2019 Feb 28;56(2):153-165. Epub 2018 Dec 28.

Division of Emergency Medicine, Washington University School of Medicine, St. Louis, Missouri.

Background: Delayed diagnoses of unstable thoracolumbar spine (TL-spine) fractures can result in neurologic deficits and avoidable pain, so it is important for clinicians to reach prompt diagnostic decisions. There are no validated decision aids for determining which trauma patients warrant TL-spine imaging.

Objective: Our aim was to quantify the diagnostic accuracy of the injury mechanism, physical examination, associated injuries, clinical decision aids, and imaging for evaluating blunt TL-spine trauma patients. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.10.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369004PMC
February 2019
1 Read

The Dangers of Spear Tackling: A Case Report of a NEXUS-negative High School Football Player.

J Emerg Med 2019 Feb 28;56(2):185-190. Epub 2018 Dec 28.

Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Background: Although "spear tackling" is known to be a risk factor for cervical spine injury due to axial loading of the neck, and although this technique was officially banned from American football in 1976, football-associated cervical spine injuries continue to be reported. This case highlights the importance of recognizing high-risk mechanisms for cervical spine injury, and specifically the danger of spear tackling among football players at all levels.

Case Report: A 16-year-old male high school football player presented to the pediatric emergency department for a neck injury sustained after spear tackling during a football game. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.11.007DOI Listing
February 2019

Odontoid fracture with missed diagnosis of Transverse Atlantal Ligament (TAL) injury resulting in late-onset instability.

Surg Neurol Int 2018 28;9:240. Epub 2018 Nov 28.

Department of Ortho-Spine Surgery, Sir Ganga Ram Hospital, New Delhi, India.

Background: Concurrent injuries to both the odontoid and transverse atlantal ligament are rare and can be easily missed. Failure to diagnose both lesions potentially leads to the late onset of sagittal plane instability and acute myelopathy. Here, we present a patient with an odontoid fracture whose transverse atlantal ligament (TAL) injury was originally missed on magnetic resonance imaging (MRI) and computed tomography (CT) scans. Read More

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http://dx.doi.org/10.4103/sni.sni_315_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287336PMC
November 2018
1 Read

Risk Factors for Sacral Insufficiency Fractures in Cervical Cancer After Whole Pelvic Radiation Therapy.

Anticancer Res 2019 Jan;39(1):361-367

Department of Radiology, Nihon University School of Medicine, Tokyo, Japan.

Aim: To evaluate the incidence and risk factors of sacral insufficiency fractures (SIFs), particularly dose-volume histogram (DVH) parameters, in patients with cervical cancer after whole pelvic radiation therapy (WPRT).

Patients And Methods: The medical records of 61 patients with cervical cancer who underwent WPRT were retrospectively reviewed. The cumulative incidence of SIF, as well as the risk factors that could affect its incidence were assessed. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13120DOI Listing
January 2019
7 Reads

Rare Case of Bilateral Pure Facet Joint Dislocation of Upper Lumbar Spine without Facet Fracture: A Case Report.

J Orthop Case Rep 2018 May-Jun;8(3):58-60

Department of Spine surgery, MIOT international hospital, Chennai. India.

Introduction: Bilateral facetal dislocation without facet fracture, although common in cervical spine, is a very rare entity in lumbar spine with <15 cases reported so far. Such injuries are very unstable involving all the three columns. Neurological insult and visceral affection are commonly associated with bilateral facetal dislocation. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298719PMC
December 2018
1 Read

Health-related quality of life in Romanian postmenopausal women with osteoporosis and fragility fractures.

Clin Interv Aging 2018 3;13:2465-2472. Epub 2018 Dec 3.

Department of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Objectives: Osteoporosis is a common skeletal disorder characterized by decreased bone mass and increased susceptibility to fractures, which are associated with pain and decrease in physical function, social function, and well-being, which are all aspects of quality of life (QoL). The purpose of this study was to evaluate the burden of osteoporosis and fragility fractures in Romanian postmenopausal women from Cluj County using the 36-Item Short Form Health Survey (SF-36) and Quality of life questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) questionnaires.

Materials And Methods: An analytical cross-sectional study on 364 postmenopausal women was carried out between June 2016 and August 2017 in the Clinical Rehabilitation Hospital in Cluj-Napoca, Cluj County, Romania. Read More

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http://dx.doi.org/10.2147/CIA.S190440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284528PMC
February 2019
3 Reads

Association of moderate/severe vertebral fractures with reduced trabecular volumetric bone density in older women and reduced areal femoral neck bone density in older men from the community: A cross-sectional study (SPAH).

Maturitas 2019 Feb 27;120:61-67. Epub 2018 Nov 27.

Bone Metabolism Laboratory, Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. Electronic address:

Background: Many vertebral fractures (VF) occur in individuals classified by DXA as being at low risk of fragility fractures. The aim of this study was to verify the association between VF and peripheral bone microarchitecture and strength parameters (SP) using, in addition to DXA, high-resolution peripheral quantitative computed tomography (HR-pQCT) and axial bone microarchitecture using the trabecular bone score (TBS).

Study Design: Cross-sectional study of 276 community-dwelling subjects aged ≥65 years from the SPAH study cohort. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.11.019DOI Listing
February 2019
1 Read