Search Our Scientific Publications & Authors

JAAD Case Rep 2023 Jul 10;37:5-7. Epub 2023 May 10.

Faculty of Health Sciences, Division of Dermatology, McMaster University, Hamilton, Ontario, Canada.

J Cutan Med Surg 2023 5;27(4):375-387. Epub 2023 Jun 5.

Faculté de Médecine, Université Saint-Joseph, Beirut, Lebanon.

Background: With light-assisted hair removal becoming widely used, reports of adverse effects are increasing.

Objective: To review all the reported optical incidents and cutaneous complications of laser or intense pulse light-assisted hair removal.

Methods: A PubMed database systematic search was performed to identify studies reporting such adverse events before July 2022 using the Mesh terms "adverse effects" AND "hair removal" AND ("laser" OR "intense pulse light"). Read More

Int J Womens Dermatol 2022 Oct 11;8(3):e039. Epub 2022 Aug 11.

Department of Histopathology, Prince Faisal Cancer Center, King Fahd Specialist Hospital, Buraydah, Qassim, Saudi Arabia.

Pediatr Dermatol 2021 Jul 1;38(4):950-951. Epub 2021 Jun 1.

AdventHealth Medical Group, Orlando, FL, USA.

Fox-Fordyce disease is a chronic pruritic disorder of apocrine sweat glands that is often associated with significantly decreased quality of life. With no definitive cure, affected patients are often treated with topical corticosteroids as first-line therapy, but evidence for treatment of refractory cases is limited. We present an adolescent with Fox-Fordyce disease successfully treated for symptomatic relief with botulinum toxin type A injections. Read More

J Cosmet Dermatol 2022 Feb 18;21(2):482-500. Epub 2021 Apr 18.

Dermatologic SurgiCenter, Philadelphia, PA, USA.

Background: Fox-Fordyce (FFD), also known as apocrine military, is an uncommon chronic inflammation of the apocrine sweat glands. It is characterized by pruritic, papular eruptions in apocrine-gland-bearing regions. FFD was described a century ago, but the exact pathogenesis of the disease and the management are not well understood. Read More

Skin Appendage Disord 2020 Jul 9;6(4):247-249. Epub 2020 Jun 9.

Department of Dermatology and STD, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, Delhi, India.

Fox-Fordyce disease (FFD) is a rare chronic skin disease of the apocrine unit. It presents chiefly in postpubertal females as grouped, monomorphic, skin-colored follicular papules associated with intense pruritus commonly in axillae but may involve pubic, perineal, areolar, and umbilical areas [. 2018;93(1):161-2]. Read More

Actas Dermosifiliogr (Engl Ed) 2020 Oct 17;111(8):706-707. Epub 2020 Jun 17.

Servicio de Dermatología, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, España.

J Cosmet Laser Ther 2020 Apr 7;22(3):126-127. Epub 2020 Jun 7.

Skin Research Center, Guilan University of Medical Sciences , Rasht, Iran.

Fox-Fordyce disease (FFD) is an uncommon apocrine disorder. We reported a 26-year-old woman with bilateral axillary pruritic papular lesions following 2 sessions of treatment with Diode (800 nm) laser for axillary hair removal. No lesions were developed in the other treated areas. Read More

Dermatol Ther 2020 Mar 14;33(2):e13223. Epub 2020 Jan 14.

Dermatovenerology Department, Celje General and Teaching Hospital, Celje, Slovenia-EU, Institute of Anatomy, Histology, and Embryology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.

Fox-Fordyce disease (FFD) is a rare pruritic dermatosis whose etiology has not been fully explored. It is mostly seen in women and presents as pruritic follicular papules at the apocrine (gland-bearing) regions, including the axilla, groins, perineum, and areola mammae, as well as the umbilicus. Treatment for FFD is extremely challenging in that there is no curative treatment for it. Read More

Australas J Dermatol 2020 May 17;61(2):188-189. Epub 2019 Nov 17.

Byth Medical Pty Ltd, Wesley Hospital, Auchenflower, Queensland, Australia.

Pan Afr Med J 2019 2;33. Epub 2019 May 2.

Service de Dermatologie et Vénérologie, Hôpital Universitaire Hassan II, Fès, Maroc.

An Bras Dermatol 2018 ;93(4):562-565

Clínica Dermatológica Valdés - León, Guanajuato, Mexico.

Fox-Fordyce disease is a relatively infrequent pathology of the apocrine glands that affects almost exclusively young women. The disease is characterized by the presence of pruritic follicular papules mainly in the armpits that respond poorly to treatment and severely affect the patient's quality of life. We report two cases with clinical diagnosis and histopathological confirmation, presenting perifollicular xanthomatosis on histological examination, recently described as a distinctive, consistent, and specific feature of this disease. Read More

Adv Biomed Res 2018 24;7:71. Epub 2018 Apr 24.

Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

An Bras Dermatol 2018 ;93(1):161-162

Department of Dermatology, China-Japan Friendship Hospital - Beijing, China.

Hautarzt 2018 Apr;69(4):313-315

Universitäts-Hautklinik Heidelberg, Ruprecht-Karls Universität Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland.

Fox-Fordyce disease (FFD), also known as apocrine miliaria, is a rare and chronic skin disease characterized by itching and skin-colored, light brown or yellowish papules. FFD typically affects postpubertal young women between 13 and 35 years. The etiology is not completely known, but a hormonal component is in discussion. Read More

Pol J Pathol 2017 ;68(4):277-283

President of prewar Lvov and Polish Republic on Exile, associate professor Stanisław Ostrowski was a dermatologist with a keen interest in dermatopathology. This study was based on original resources, which - mainly reports of his own authorship - were focused on dermatopathology. Stanisław Ostrowski provided excellent description of naevus epitheliomatosus sebaceus Wolters-Friboes both in Polish and German to be cited after decades in renowned handbooks of dermatopahtology published by Springer Verlag. Read More

Photodermatol Photoimmunol Photomed 2016 Sep 28;32(5-6):311-313. Epub 2016 Sep 28.

Department of Pathology, School of Medicine, Göztepe Training and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey.

J Invest Dermatol 2017 Jan 1;137(1):38-45. Epub 2016 Sep 1.

Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

Sweat glands are critical for thermoregulation. The single tubular structure of sweat glands has a lower secretory portion and an upper reabsorptive duct leading to the secretory pore in the skin. Genes that determine sweat gland structure and function are largely unidentified. Read More

Clin Dermatol 2016 11;34(3):335-43. Epub 2016 Feb 11.

Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Department of Dermatology, Rhode Island Hospital, Providence, Rhode Island.

A switch from cell-mediated to humoral immunity (helper T 1 [Th1] to helper T 2 [Th2] shift) during gestation plays a key role in placental immune tolerance. As a result, skin diseases that are Th2 mediated often worsen, whereas skin diseases that are Th1 mediated often improve during gestation. Also, due to fluctuations in glandular activity, skin diseases involving sebaceous and eccrine glands may flare, whereas those involving apocrine glands may improve during pregnancy. Read More

Eur J Dermatol 2016 Apr;26(2):212-3

Dpt of Dermatology, University of Franche Comté EA3181 and University Hospital, Besançon.

Indian J Sex Transm Dis AIDS 2016 ;37(1):65-7

Department of Dermatology, Venereology and Leprosy, Saveetha Medical College and Hospital, Kancheepuram, Tamil Nadu, India.

Fox-Fordyce disease is a rare, chronic skin disorder which affects the apocrine areas. This disease is due to the obstruction of the apocrine sweat duct. Extragenital regions are commonly affected than the genital region. Read More

J Eur Acad Dermatol Venereol 2016 Sep 2;30(9):1578-82. Epub 2016 May 2.

Division of Dermatology, St Georges University Hospital, Beirut, Lebanon.

Background: Fox-Fordyce Disease (FFD) is a rare chronic inflammatory skin disease of the apocrine glands, mainly affecting post-pubertal women. It involves apocrine gland-bearing areas including the axilla, areola, anogenital area and umbilicus. FFD induced by laser hair removal is a newly reported entity of unknown pathogenesis. Read More

Int Wound J 2016 Oct 12;13(5):1016-9. Epub 2016 Apr 12.

Department of Plastic and Reconstructive Surgery, The Catholic University of Korea, Seoul, Republic of Korea.

Fox-Fordyce disease (FFD) is a rare chronic disorder characterised by persistent inflammation because of the obstruction of apocrine sweat glands, which is a key factor of pathogenesis. The treatment of FFD is known to be difficult, and the modalities of treatment have not yet been widely studied. We report the successful treatment of a case of bilateral areolar FFD by a combination of surgical excision and 1550-nm fractionated erbium glass laser in an 18-year-old woman. Read More

JAAD Case Rep 2016 Jan 24;2(1):1-3. Epub 2015 Dec 24.

Chicago Cosmetic Surgery and Dermatology, Chicago, Illinois.

J Dtsch Dermatol Ges 2016 Mar;14(3):340

Sultan Qaboos Univ Med J 2016 Feb 2;16(1):e119-20. Epub 2016 Feb 2.

Pathology, Virgen de las Nieves Hospital, Granada, Spain.

J Dtsch Dermatol Ges 2016 Jan;14(1):62-3

National Skin Centre, Singapore.