93,832 results match your criteria Forensic Science International: Genetics [Journal]


Stability of synthetic cathinones in blood and urine.

Forensic Sci Int 2018 Dec 6;295:36-45. Epub 2018 Dec 6.

Jagiellonian University, Faculty of Chemistry, Gronostajowa 2, 30-387 Kraków, Poland.

Introduction: Although there is an observed decline in the number of new psychoactive substances entering the drug market, this phenomenon is still a significant public health problem. Synthetic cathinones are the second largest group of new substances and currently belong to the most frequently confiscated. Their availability and prevalence cause that they are often abused. Read More

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December 2018
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Evaluation of the Microhaplotype markers in kinship analysis.

Electrophoresis 2018 Dec 17. Epub 2018 Dec 17.

Department of Forensic Genetics, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, 610041, Sichuan, P. R. China.

Microhaplotype markers are emerging forensic genetic markers which may supplement existing markers. Consisting of 2-4 SNPs with an extent of <200 bp, microhaplotype can be genotyped through massively parallel sequencing (MPS) technology. Articles which have been published suggested that microhaplotype markers have good application prospect in forensics. Read More

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December 2018
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Fractal Self-Structure and Psychological Resilience.

Nonlinear Dynamics Psychol Life Sci 2019 Jan;23(1):57-78

Chapman University, Orange, CA.

Since the mid 1980's, mainstream social psychology investigations of self-complexity and psychopathology have produced contradictory results. These results are likely the result of a lack of theoretical and methodological grounding in complexity theory. The current study proposes that the self has an interconnected fractal structure, and that this structure may be reflected within inverse-power law (IPL) distributions of response times to self-related questions. Read More

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January 2019

Factions Influencing the Filing of Complaints, Their Investigation, and Subsequent Legal Judgment in Cases of Sexual Assault.

J Forensic Sci 2018 Dec 17. Epub 2018 Dec 17.

University Center of Legal Medicine, Geneva and Lausanne, Geneva site de Genève, 1 rue Michel Servet, 1211, Genève 4, Switzerland.

In Geneva, examination of victims of sexual assault is performed by a gynecologist and a medical examiner. 48% of the victims file a complaint and we wanted to investigate the factors leading to file a complaint, those leading the Prosecutor to go to trial, and those influencing a conviction. Between 2006 and 2012, 676 victims of sexual assault were investigated (averaged age 26 year, mean 22). Read More

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December 2018

Association of Friday School Report Card Release With Saturday Incidence Rates of Agency-Verified Physical Child Abuse.

JAMA Pediatr 2018 Dec 17. Epub 2018 Dec 17.

Division of Child Protection and Forensic Pediatrics, Department of Pediatrics, University of Florida, Jacksonville.

Importance: Corporal punishment is a leading risk factor for physical abuse. Strong anecdotal evidence from physicians and other professionals working in child protection suggest that punishment-initiated physical abuse for school-aged children increases after release of report cards. However, no empirical examination of this association has occurred. Read More

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December 2018

An examination of Psychopathy Checklist-Revised latent factor structure via exploratory structural equation modeling.

Psychol Assess 2018 Dec 17. Epub 2018 Dec 17.

Department of Psychology, University of Otago.

The Psychopathy Checklist-Revised (PCL-R; Hare, 1991, 2003) is widely used in clinical and forensic practice. Its latent factor structure has been subject to debate and controversy for almost 40 years. Various principal component and factor models have been proposed. Read More

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December 2018

Development of a 21-item short form of the Attitudes to Sexual Offenders (ATS) Scale.

Law Hum Behav 2018 Dec 17. Epub 2018 Dec 17.

Department of Psychology, Nottingham Trent University.

The Attitudes to Sexual Offenders scale (ATS; Hogue, 1993) is one of the most widely used measurement instruments for assessing views about sexual offenders. The ATS has been used in a variety of contexts, most commonly in comparing forensic professionals and nonprofessionals in relation to their views about this population. This article offers a review of the methods used to examine attitudes toward sexual offenders currently available, before systematically outlining the validation of a 21-item shortened version of the ATS measure (the ATS-21). Read More

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December 2018

Females who maltreat animals.

Behav Sci Law 2018 Nov;36(6):752-765

Saint Louis University School of Medicine.

Studies of animal maltreatment and of untoward or abnormal aggression predominantly involve male subjects, raising the question as to whether females who engage in such behaviors are like, or fundamentally different than, their male counterparts. Inquiry to address this issue could pertain to gender similarities and differences; moreover, it could provide greater understanding of the behavior itself, in this case, animal maltreatment. Of the various patterns of animal maltreatment in the literature, there are enough studies with gender addressed to allow some observations on two patterns: animal cruelty in childhood and animal hoarding. Read More

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November 2018

Mortality for neurological diseases and pesticides: etiological hypotheses by a spatial analysis in the province of Pavia.

Med Lav 2018 Dec 20;109(6):420-434. Epub 2018 Dec 20.

Unit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Italy.

Background: Neurological and neurodegenerative diseases are multifactorial and their causes are not well understood yet. Among the relevant risk factors, pesticides and the productive activities in which they are used are included.

Objectives: To evaluate the association of mortality from neurological diseases within the Province of Pavia (Italy) with the agricultural activities, as a proxy of pesticides exposure. Read More

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December 2018

Do psychopathic traits impair autobiographical memory for emotional life experiences?

Memory 2018 Dec 15:1-13. Epub 2018 Dec 15.

b Department of Computer Science , University of Bari Aldo Moro , Bari , Italy.

We examined the relationship between psychopathic traits and autobiographical memory (AM) for emotional life experiences in both a community (Study 1) and forensic sample (Study 2). Considering that psychopathy is traditionally linked to an impairment in the processing of emotion, we hypothesised an emotional deficit of AM in individuals with high levels of psychopathic traits. Participants in both samples were asked to recall an emotionally charged event, and were then administered the Psychopathic Personality Inventory-Revised, the Flashbulb Memory Checklist, and the Autobiographical Memory Characteristics Questionnaire. Read More

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December 2018
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[Analysis of medical diagnostic reports (constats) on dental injuries from terminological, dental and forensic medical points of view].

Orv Hetil 2018 Dec;159(51):2154-2161

Általános Orvostudományi Kar, Igazságügyi Orvostani Intézet, Debreceni Egyetem Debrecen.

Writing a constat is a professional skill required of every general physician and dentist. Constats are issued by healthcare providers on the investigating authority's, court's or injured person's request. This document is an official judicial evidence, a record of medical examination, and it is also a medical opinion which can determine the outcome of the subsequent legal process. Read More

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December 2018

Pattern Analysis of Short Tandem Repeats Allele Frequencies among the Population of Khuzestan Province, South of Iran.

Avicenna J Med Biotechnol 2018 Oct-Dec;10(4):257-260

Department of Forensic Medicine, Khuzestan Legal Medicine Organization, Ahvaz, Iran.

Background: The basis of genetic fingerprinting and DNA profiling in forensic laboratories is the use of Short Tandem Repeats (STRs) according to local and ethnical genetics characteristics.

Methods: Forensic parameters and allele frequencies for 15 autosomal STRs in 100 unrelated individuals from Khuzestan province, south Iran were determined. PCR was carried out for amplification of STRs and GeneMapper ID software was used for genotyping and allelic analyzing. Read More

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December 2018

Canine environmental hyperthermia: a case series.

Authors:
Adam Stern

J Vet Med Sci 2018 Dec 14. Epub 2018 Dec 14.

Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida.

Cases of hyperthermia caused by exposure to high environmental temperature are not uncommonly encountered in dogs. The circumstances surrounding the exposure to high environmental temperature may be accidental or intentional; thus highlighting the importance to perform a forensic autopsy. This report documents three cases of canine environmentally induced hyperthermia and all dogs in this report died less than 6 hrs after exposure to the high environmental temperatures. Read More

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December 2018

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need.

Alzheimers Dement 2018 Dec 13. Epub 2018 Dec 13.

Department of Pharmacology & Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA. Electronic address:

Alzheimer's disease and related dementias (ADRDs) are a global crisis facing the aging population and society as a whole. With the numbers of people with ADRDs predicted to rise dramatically across the world, the scientific community can no longer neglect the need for research focusing on ADRDs among underrepresented ethnoracial diverse groups. The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART; alz. Read More

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December 2018

A National Wastewater Monitoring Program for a better understanding of public health: A case study using the Australian Census.

Environ Int 2018 Dec 14. Epub 2018 Dec 14.

Queensland Alliance for Environmental Health Sciences, The University of Queensland, Woolloongabba, Queensland 4102, Australia.

Wastewater contains a large range of biological and chemical markers of human activity and exposures. Through systematic collection and analysis of these markers within wastewater samples it is possible to measure the public health of whole populations. The analysis of effluent and biosolids can also be used to understand the release of chemicals from wastewater treatment plants into the environment. Read More

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December 2018

Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial.

Lancet Neurol 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

Background: Spasticity is a major determinant of disability and decline in quality of life in patients with motor neuron disease. Cannabinoids have been approved for symptomatic treatment of spasticity in multiple sclerosis. We investigated whether cannabinoids might also reduce spasticity in patients with motor neuron disease. Read More

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December 2018
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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

Authors:
Nasim Mavaddat Kyriaki Michailidou Joe Dennis Michael Lush Laura Fachal Andrew Lee Jonathan P Tyrer Ting-Huei Chen Qin Wang Manjeet K Bolla Xin Yang Muriel A Adank Thomas Ahearn Kristiina Aittomäki Jamie Allen Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Paul L Auer Päivi Auvinen Myrto Barrdahl Laura E Beane Freeman Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Michael Bremer Hermann Brenner Adam Brentnall Ian W Brock Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Daniele Campa Brian D Carter Jose E Castelao Stephen J Chanock Rowan Chlebowski Hans Christiansen Christine L Clarke J Margriet Collée Emilie Cordina-Duverger Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Asta Försti Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Irina R Gilyazova Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Susan E Hankinson Elaine F Harkness Steven N Hart Wei He Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Milena Jakimovska Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Katarzyna Kaczmarek Vesa Kataja Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Julia A Knight Yon-Dschun Ko Veli-Matti Kosma Stella Koutros Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Jenna Lilyquist Annika Lindblom Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jan Lubiński Michael P Lux Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian Sara Margolin John W M Martens Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Usha Menon Pooja Middha Nicola Miller Fernando Moreno Anna Marie Mulligan Claire Mulot Victor M Muñoz-Garzon Susan L Neuhausen Heli Nevanlinna Patrick Neven William G Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Kenneth Offit Janet E Olson Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Julian Peto Mila Pinchev Dijana Plaseska-Karanfilska Eric C Polley Ross Prentice Nadege Presneau Darya Prokofyeva Kristen Purrington Katri Pylkäs Brigitte Rack Paolo Radice Rohini Rau-Murthy Gad Rennert Hedy S Rennert Valerie Rhenius Mark Robson Atocha Romero Kathryn J Ruddy Matthias Ruebner Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Caroline Seynaeve Mitul Shah Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Susan Slager Ann Smeets Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Christa Stegmaier Jennifer Stone Anthony J Swerdlow Rulla M Tamimi William J Tapper Jack A Taylor Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Thérèse Truong Maria Tzardi Hans-Ulrich Ulmer Michael Untch Celine M Vachon Elke M van Veen Joseph Vijai Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Drakoulis Yannoukakos Yan Zhang Wei Zheng Argyrios Ziogas Alison M Dunning Deborah J Thompson Georgia Chenevix-Trench Jenny Chang-Claude Marjanka K Schmidt Per Hall Roger L Milne Paul D P Pharoah Antonis C Antoniou Nilanjan Chatterjee Peter Kraft Montserrat García-Closas Jacques Simard Douglas F Easton

Am J Hum Genet 2018 Dec 5. Epub 2018 Dec 5.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comprised 94,075 case subjects and 75,017 control subjects of European ancestry from 69 studies, divided into training and validation sets. Read More

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December 2018
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Sudden unexpected infantile death due to undiagnosed ventricular septal defect-associated heart failure with single coronary artery.

Forensic Sci Med Pathol 2018 Dec 15. Epub 2018 Dec 15.

Department of Legal Medicine, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8521, Japan.

Ventricular septal defect (VSD) generally has a good prognosis unless complicated by heart failure (HF). We report a case of sudden infant death because of clinically undiagnosed VSD in a seemingly healthy 16-day-old boy. Although a cardiac murmur was auscultated at birth, detailed clinical examination was not performed. Read More

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December 2018
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Unhealthy lifestyle and oxidative damage in childhood obesity.

Eat Weight Disord 2018 Dec 15. Epub 2018 Dec 15.

Dietetics and Clinical Nutrition Laboratory, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

Purpose: Oxidized LDL cholesterol (oxLDL) has been considered as a sensor of oxidative stress (OS) in childhood obesity. We integrated and related our oxLDL existing results previously assessed in overweight/obese children to lifestyle variables to investigate OS-related lifestyle variables.

Methods: 178 Caucasian children/adolescents have been evaluated and according to BMI percentiles have been classified as normal weight (BMI < 75th); overweight (BMI 75-97th) and obese (BMI > 97th). Read More

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December 2018

Histological dating of subdural hematoma in infants.

Int J Legal Med 2018 Dec 15. Epub 2018 Dec 15.

Forensic Department, APHM, La Timone, 264 rue St Pierre, 13385, Marseille, Cedex 05, France.

Background: After infant deaths due to non-accidental head injury (NAHI) with subdural hematoma (SDH), the magistrates ask experts to date the traumatic event. To do so, the expert only has tools based on adult series of NAHI. We aimed to develop an SDH dating system applicable to infants aged under 3 years. Read More

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December 2018

"Getting to zero" HIV/AIDS requires effective addressing of HIV issues in LGBT community.

Clin Ter 2018 Nov-Dec;169(6):e269-e271

Department of Microbiology, Panjab University, Chandigarh, India.

This communication is regarding the necessity to address the HIV-related needs of LGBTQIA+ community (Lesbian, Gay, Bisexual, Transgender/transsexual, Queer/Questioning, Intersex, Asexuality, and others) for attaining the 'GETTING TO ZERO' theme for zero new HIV infections, zero AIDS-related deaths and zero discrimination. Most of the times, prevention of HIV/AIDS is talked about in terms of faithfulness to one's partner, use of protective devices such as condoms, pre and post exposure prophylaxis, using anti-retroviral therapies and use of microbicides, behavior change etc. HIV-related issues are however, one of the pertinent issues that needs to be effectively addressed in the LGBTQIA+ community. Read More

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December 2018
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Compound stutter in D2S1338 and D12S391.

Forensic Sci Int Genet 2018 Dec 7;39:50-56. Epub 2018 Dec 7.

Center for Human Identification, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA; Department of Microbiology, Immunology and Genetics, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA.

Compound repeats provide a testing ground for evaluating hypotheses on the causes and consequences of stutter. As compound repeats have two repeating motifs, each motif may produce stutter variants; thus as the repeat within the locus is compound, so is the resultant stutter. Further, the rates of stutter formation between these motifs may not be independent. Read More

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December 2018

DNA based method for determining source country of the short beaked echidna (Tachyglossus aculeatus) in the illegal wildlife trade.

Forensic Sci Int 2018 Dec 5;295:46-53. Epub 2018 Dec 5.

Australian Centre for Wildlife Genomics, Australian Museum Research Institute, 1 William Street, Sydney, Australia. Electronic address:

The illegal trade in wild animals being sold as 'captive bred' is an emerging issue in the pet and zoo industry and has both animal welfare and conservation implications. DNA based methods can be a quick, inexpensive, and definitive way to determine the source of these animals, thereby assisting efforts to combat this trade. The short beaked echidna (Tachyglossus aculeatus) is currently one of the species suspected to be targeted in this trade. Read More

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December 2018

Using virtual reality for forensic examinations of injuries.

Forensic Sci Int 2018 Nov 16;295:30-35. Epub 2018 Nov 16.

Institute of Forensic Medicine, University of Zurich, Winterthurerstrasse 190/52, CH-8057 Zürich, Switzerland; 3D Zentrum Zürich, Winterthurerstrasse 190/52, CH-8057 Zürich, Switzerland. Electronic address:

The ability to accurately determine injury dimensions is an essential property of forensic documentation. The current standard for injury documentation is photography using a scale to approximate the injury dimensions in the image. The technical qualities of the photograph, such as orthogonality, depth of the field and sharpness of the desired area, are vital to obtaining a correct measurement. Read More

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November 2018

Virtual reconstruction of paranasal sinuses from CT data: A feasibility study for forensic application.

Diagn Interv Imaging 2018 Dec 12. Epub 2018 Dec 12.

LiiE, EA 4264, CERIMED, Aix-Marseille University, 13005 Marseille, France.

Purpose: The purpose of this study was to report the feasibility of computed modelization and reconstitution of the paranasal sinuses, before and after trauma, from CT data.

Materials And Methods: We modeled and reconstructed the paranasal sinuses of two patients (A and B), before and after trauma, using two different softwares (3DSlicer and Blender). Both patients had different numbers and locations of fractures. Read More

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December 2018

C-terminus of heat shock protein 60 can activate macrophages by lectin-like oxidized low-density lipoprotein receptor 1.

Biochem Biophys Res Commun 2018 Dec 12. Epub 2018 Dec 12.

Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. Electronic address:

Immune responses against antigens generally require an efficient activation of antigen-presenting cells (APCs). Currently, the targeting of vaccine antigens to APCs has emerged as a promising strategy for boosting vaccine immunogenicity. Here, we reported that the C-terminus of heat shock protein 60 (HSP60C) can activate mouse peritoneal macrophages to secret a series of cytokines, and phosphorylation of p38 mitogen-activated protein kinase (MAPK) and NF-κB p65 was involved in the pathway. Read More

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December 2018

Optimizing denaturing HPLC as a robust technique for identification of Short Tandem Repeats (STR) in forensic medicine.

J Forensic Leg Med 2018 Dec 10;61:108-114. Epub 2018 Dec 10.

Department and Biotechnology Research Center, Semnan University of Medical Sciences, Semnan, Iran. Electronic address:

Introduction: Short Tandem Repeats (STRs) are defined as short lengths of 2-7 base pairs spreading through human genome which due to their highly diverse individually distribution are widely applied for identity detection and other forensic medicine purposes. Burdening considerable costs by the conventional methods such as capillary electrophoresis, we aimed to compare concomitant usage of multiplex PCR and denaturing high-performance liquid chromatography (DHPLC) as cheap, fast, highly accurate, and more accessible methods, with capillary electrophoresis (CE) to evaluate their potential for early screening of STRs.

Materials And Methods: The present study randomly included 20 blood samples from the subjects referred to forensic medicine of Semnan, Iran. Read More

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December 2018
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Evaluation of an untargeted chemometric approach for the source inference of ignitable liquids in forensic science.

Forensic Sci Int 2018 Dec 5;295:8-18. Epub 2018 Dec 5.

UMR Ingénierie Procédés Aliments, AgroParisTech, Inra, Université Paris-Saclay, 91300 Massy, France. Electronic address:

Recent research efforts in the domain of fire debris analysis have been mainly oriented towards the development of innovative analytical procedures and chemometric approaches for the detection and classification of ignitable liquids in fire specimens according to the ASTM E1618. However, less attention has been brought to the question of the source inference of ignitable liquids. Infer the identity of source of ignitable liquids recovered from arson sites is still a challenging and ongoing research area. Read More

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December 2018

Nonlinear methods of vehicle velocity determination based on inverse systems and tensor products of Legendre polynomials in compact car class.

Forensic Sci Int 2018 Dec 4;295:19-29. Epub 2018 Dec 4.

Institute of Mathematics, Lodz University of Technology, 215 Wolczanska Str., 90-924 Lodz, Poland. Electronic address:

The article presents research on the methods of crash velocity determination based on the Compact car class. The database used in the research is provided by the NHTSA (National Highway Traffic Safety Administration) and includes numerous frontal crash tests, which allowed the determination of the mathematical model parameters. Two methods are presented that enable the determination of vehicle velocity before the collision. Read More

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December 2018
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Evidence based survey of the distribution volume of ethanol: Comparison of empirically determined values with anthropometric measures.

Forensic Sci Int 2018 Nov 13;294:124-131. Epub 2018 Nov 13.

Principal Forensic Services, Bromley, Kent, UK.

The Widmark equation is commonly used when blood alcohol calculations are required in forensic and legal medicine, such as in road-traffic cases and alcohol-related deaths. An important biological variable in this connection is the volume of distribution (V) of ethanol, which is commonly referred to as the rho-factor. Although a person's V can be determined empirically through controlled drinking experiments, this approach is not very practical in reality. Read More

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November 2018

Are parents at a higher risk for secondary traumatic stress?: How interviewing child victims impacts relationships with forensic interviewer's friends and family.

Child Abuse Negl 2018 Dec 12;88:275-287. Epub 2018 Dec 12.

School of Arts & Sciences, University of Houston-Victoria, 3007 N. Ben Wilson, Victoria, TX, 77904, United States. Electronic address:

Background: Forensic interviewers are at a heightened risk for secondary traumatic stress (STS) due to their frequent interactions with victims of child maltreatment (Bonach & Heckert, 2012). To date, however, few studies have examined the negative effects of this work on interviewers' social and emotional well-being.

Objective: The present study seeks to explore the effect of STS on the relationships of forensic interviewers, including those with friends, family, and their respective children. Read More

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December 2018

Factors predicting early dropout from dialectical behaviour therapy in individuals with borderline personality disorder.

Actas Esp Psiquiatr 2018 Nov 1;46(6):226-33. Epub 2018 Nov 1.

Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain) Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona (Spain) Institut d'Investigació Biomèdica- Sant Pau (IIB-SANT PAU), Barcelona (Spain) Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM (Spain).

Background: Dialectical behaviour therapy skills training (DBT-ST) has proven effective to treat individuals with borderline personality disorder (BPD). However, therapy still faces the problem of early dropout. The aim of the present study is to examine which factors are associated with early dropout from DBT-ST in a sample of subjects with BPD. Read More

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November 2018

Notoginsenoside R1 protects oxygen and glucose deprivation-induced injury by upregulation of miR-21 in cardiomyocytes.

J Cell Biochem 2018 Dec 14. Epub 2018 Dec 14.

Department of Cardiology, Jining No. 1 People's Hospital, Jining, Shandong, China.

Notoginsenoside R1 (NG-R1) is a major component of Panax notoginseng, which has been used clinically for the treatment of diabetic nephropathy for centuries in China. This study aimed to reveal the functional impacts and the underlying mechanisms of NG-R1 on oxygen-glucose deprivation (OGD)-injured cardiomyocytes. Rat cardiomyocyte line H9c2 and primary cardiomyocytes were subjected to OGD with or without NG-R1 treatment. Read More

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December 2018
2 Reads

Tongue position and its relation to the cause of death and sequential stages of body decomposition observed during 608 forensic post-mortems.

Int J Legal Med 2018 Dec 14. Epub 2018 Dec 14.

Department of Statistics, University of Pretoria, Pretoria, South Africa.

The purpose of this study was to document tongue position and its relation to the cause of death and sequential stages of body decomposition, as observed during the routine forensic pathological examination of bodies. The sample of 608 included all bodies examined by the first and third authors during the period April 2016 to September 2016. Tongue position was recorded in all cases where position of the tongue could be visually determined. Read More

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December 2018

Validation of the short version of the Van Lieshout Test in an Italian population with cervical spinal cord injuries: a cross-sectional study.

Spinal Cord 2018 Dec 14. Epub 2018 Dec 14.

Department of Public Health and Infection Disease, Sapienza University of Rome, Rome, Italy.

Study Design: Psychometric study.

Objective: To validate the Italian version of the Van Lieshout Test Short Version (VLT-SV) with a spinal cord injury population.

Setting: Three Italian spinal units. Read More

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December 2018

Moringa oleifera extract attenuates the CoCl induced hypoxia of rat's brain: Expression pattern of HIF-1α, NF-kB, MAO and EPO.

Biomed Pharmacother 2019 Jan 20;109:1688-1697. Epub 2018 Nov 20.

Biochemistry Department, Faculty of Science, Jeddah University, KSA, Egypt; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt.

Hypoxia-induced oxidative stress and apoptosis are the major hallmark explanations underlying brain dysfunction. Hypoxia in the current study was induced by Cobalt chloride (CoCl) treatment in rats. The aim of this experiment was to explore the potential ameliorative potency of Moringa oleifera ethanolic extract (MO) against experimentally induced hypoxia on the structure and function of the rat's brain. Read More

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January 2019
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Improvement in cognitive biases after group psychoeducation and metacognitive training in recent-onset psychosis: A randomized crossover clinical trial.

Psychiatry Res 2018 Dec 25;270:720-723. Epub 2018 Oct 25.

Department of Mental Health, Parc Taulí Hospital Universitari, Institut d'Investigació Sanitària Parc Taulí (I3PT), Universitat Autònoma de Barcelona (Department of Psychiatry and Forensic Medicine). CIBERSAM. Sabadell, Spain. Electronic address:

Metacognitive training (MCT) improves cognitive biases in psychosis. We aimed to explore whether the effectiveness of the combination of psychoeducation and MCT group treatments on cognitive biases differed if the combination was started by psychoeducation or by MCT. Fourty-nine stable patients with a recent-onset psychosis were randomized to two different sequences: MCT + psychoeducation vs psychoeducation + MCT. Read More

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December 2018

Estimating the probability of abusive head trauma after abuse evaluation.

Child Abuse Negl 2018 Dec 11;88:266-274. Epub 2018 Dec 11.

Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, United States.

Background: Evidence-based, patient-specific estimates of abusive head trauma probability can inform physicians' decisions to evaluate, confirm, exclude, and/or report suspected child abuse.

Objective: To derive a clinical prediction rule for pediatric abusive head trauma that incorporates the (positive or negative) predictive contributions of patients' completed skeletal surveys and retinal exams.

Participants And Setting: 500 acutely head-injured children under three years of age hospitalized for intensive care at one of 18 sites between 2010 and 2013. Read More

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December 2018
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The high prevalence of pre-existing mental health complaints in clients attending Saint Mary's Sexual Assault Referral Centre: Implications for initial management and engagement with the Independent Sexual Violence Advisor service at the centre.

J Forensic Leg Med 2018 Dec 5;61:102-107. Epub 2018 Dec 5.

Saint Mary's Sexual Assault Referral Centre, York Place, Oxford Road, Manchester, M13 9WL, UK. Electronic address:

Background: The Saint Mary's Sexual Assault Referral Centre has a unique service delivery model whereby it provides an integrated physical and psychological support services to clients, women men and children, living in Greater Manchester. The service is available to those who have reported rape or sexual assault, whether this is recent or historic. Clients living in surrounding areas of Cheshire are provided with forensic and medical services at Saint Mary's Centre, with follow-up care provided locally, as appropriate. Read More

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December 2018

Subtypes of aggression in intermittent explosive disorder.

J Psychiatr Res 2018 Oct 19;109:164-172. Epub 2018 Oct 19.

McLean Hospital, Harvard Medical School, United States.

Research in aggression has distinguished two major subtypes of aggressive behavior: hostile and instrumental. Previous research has examined these subtypes in healthy individuals and forensic samples but not in intermittent explosive disorder (IED), a disorder characterized by recurrent and severe aggressive behavior. We examined aggression subtypes in individuals with IED, healthy subjects, and psychiatric control subjects. Read More

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October 2018

Human DNA degradation assessment and male DNA detection by quantitative-PCR followed by high-resolution melting analysis.

Forensic Sci Int 2018 Nov 29;295:1-7. Epub 2018 Nov 29.

Centro de Referencia en Identificación Genética Humana de la Universidad de Buenos Aires, Cátedra de Genética Forense y Servicio de Huellas Digitales Genéticas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 956, CP 1113, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas-CONICET, Godoy Cruz 2290, CP 1425, Ciudad Autónoma de Buenos Aires, Argentina.

We developed a q-PCR technique that simultaneously evaluates the extent of degradation and determines the gender of a human DNA donor. QYDEG HRM is a triplex real-time PCR whose products are analysed by high-resolution melting (HRM). The system produces three amplicons: (1) transducin (beta)-like 1, Y-linked (TBL1Y) (84bp); (2) large-target sequence (DGlt) (244bp); and (3) small-target sequence (DGst) (152bp). Read More

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November 2018

Inflammation and oxidative stress are key mediators in AKB48-induced neurotoxicity in vitro.

Toxicol In Vitro 2018 Dec 11. Epub 2018 Dec 11.

Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Beyazıt, 34116 Istanbul, Turkey.

Synthetic cannabinoids were introduced into market in early 2000s; since these "legal highs" are dramatically popular among youth, it becomes a deadly problem. Synthetic cannabinoids have high affinity to cannabinoid receptors; leading to various clinical symptoms. AKB48 (Apinaca) has been classified as a third-generation synthetic cannabinoid for the first time in 2014. Read More

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December 2018
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Evaluating the Efficiency of Primer Extension Capture as a Method to Enrich DNA Extractions.

J Forensic Sci 2018 Dec 14. Epub 2018 Dec 14.

Laboratories of Molecular Anthropology and Microbiome Research, Norman, OK, 73019.

In this study, we sought to document the efficiency of primer extension capture (PEC) as a method to enrich DNA eluates of targeted DNA molecules and remove nontarget molecules from pools containing both. Efficiency of the method was estimated by comparing number of "copies in" to "copies out" by quantitative polymerase chain reaction. PEC retention of DNA targets ranging 109-288 base pairs (bps) in length was 15. Read More

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December 2018

Bone Mineral Density Adult Age Estimation in Forensic Anthropology: A Test of the DXAGE Application.

J Forensic Sci 2018 Dec 14. Epub 2018 Dec 14.

Department of Biological Sciences, North Carolina State University, 100 Eugene Brooks Avenue, Raleigh, NC, 27695.

Estimating age-at-death of individuals represented only by skeletonized human remains is a fundamental aspect of forensic anthropological casework. Recently, several researchers have proposed that bone mineral density (BMD) is a useful predictor of age-at-death in forensic contexts. Navega et al. Read More

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December 2018

Polymorphisms in the myeloid differentiation primary response 88 pathway do not explain low expression levels in sudden infant death syndrome.

Acta Paediatr 2018 Dec 14. Epub 2018 Dec 14.

Department of Forensic Sciences, Section of Paediatric Forensic Medicine, Oslo University Hospital, Oslo, Norway.

Aim: The aim of this study was to investigate if a range of known rare and common genetic variants in the Toll-like receptor 4 (TLR4) / myeloid differentiation primary response 88 (MyD88) pathway were present or overrepresented in sudden infant death syndrome (SIDS) compared to controls.

Methods: Genetic variations in the genes encoding TLR4, MyD88 and Interleukin-1 receptor-associated kinase 4 were analysed. The subjects investigated included 158 SIDS cases with a median age of 15. Read More

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December 2018

The Suitability of Grounded Theory Research for Correctional Nursing.

J Forensic Nurs 2018 Dec 13. Epub 2018 Dec 13.

Author Affiliations: Faculty of Nursing, University of Calgary.

The tension between custody and caring is particular to correctional nursing practice, including issues such as the correctional priorities of safety and security that often dominate nursing practice. The evidence that should underlie correctional nursing practice is regrettably sparse. There are two reasons a grounded theory (GT) approach is paramount for building foundational knowledge to advance correctional nursing practice. Read More

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December 2018

Exploring the Delivery of Healthcare in the Police Detention Center Through Remote Presence Technology.

J Forensic Nurs 2018 Dec 13. Epub 2018 Dec 13.

Office of the Vice-President Research, University of Saskatchewan.

Introduction: There is overwhelming evidence to support the delivery of high-quality health service at a lower cost with the use of advanced technologies. Implementing remote presence technology to expand clinical care has been fraught with barriers that limit interprofessional collaboration and optimal client outcomes. In Canada, government ministries responsible for correctional services, policing, and health are well positioned to link federal, provincial, and regional services to enhance service delivery at the point of care for individuals detained within the justice system. Read More

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December 2018
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How to Read a Research Paper: An Exercise in Critical Thinking in the Context of an Epidemiologic Study on Tamsulosin and the Risk of Dementia.

J Clin Psychiatry 2018 Dec 11;79(6). Epub 2018 Dec 11.

Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India.

A recent study of the relationship between tamsulosin and dementia found that, in propensity score-matched analyses that adjusted for measured risk factors for dementia, the use of tamsulosin to treat benign prostatic hyperplasia (BPH) was associated with a small but significant increase in the risk of incident dementia relative to untreated BPH, BPH treated with the 5α-reductase inhibitors dutasteride and finasteride, and BPH treated with the α adrenoceptor blockers doxazosin, terazosin, and alfuzosin. The choice of control groups addressed confounding by indication, confounding by disease severity, and confounding by pharmacologic drug class. The authors of the study provided a wealth of detail in their main paper and in supplementary materials, allowing an almost forensic examination of the findings. Read More

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December 2018