9,922 results match your criteria Forehead and Temple Reconstruction
Pediatrics 2018 Dec 13. Epub 2018 Dec 13.
Massachusetts General Hospital, Boston, Massachusetts; and
A healthy 17-year-old boy with a high-functioning pervasive developmental disorder presented to the emergency department after having a 4-minute episode of seizure-like activity in the setting of presumed viral gastroenteritis. Within an hour of emergency department arrival, he developed a forehead-sparing facial droop, right-sided ptosis, and expressive aphasia, prompting stroke team assessment and urgent neuroimaging. Laboratory results later revealed a serum sodium of 119 mmol/L. Read More
Physiol Meas 2018 Nov 14. Epub 2018 Nov 14.
Department of Biomedical Engineering, Seoul National University, Seoul, KOREA, REPUBLIC OF.
Objectives: This paper introduces a mathematical model that can estimate deep brain temperature during therapeutic hypothermia based on a double sensor method. Although the cerebral temperature is more important than the non-cerebral core temperature during therapeutic hypothermia, pulmonary artery, rectal, and esophageal measurements (i.e. Read More
Physiol Meas 2018 Nov 13. Epub 2018 Nov 13.
Computer Science, Australian National University, Canberra, Australian Capital Territory, AUSTRALIA.
We introduced a novel framework to identify the dynamic pattern of blood flow changes in the cutaneous superficial blood vessels of the face for "fight or flight" responses through facial thermal imaging. For this purpose, a thermal data set was collected from 32 subjects in a mock crime scenario. Five facial areas including periorbital, forehead, perinasal, cheek and chin were selected on the face. Read More
J Glaucoma 2018 Dec 11. Epub 2018 Dec 11.
Glaucoma and anterior segment, Dr. Shroff's charity eye hospital, Delhi.
Ectodermal dysplasia is a disorder that occurs due to abnormalities of ectodermal structures such as skin, teeth, hair, nails, and eccrine glands. Approximately 200 different conditions have been identified as ectodermal dysplasia, the most common being hypohidrotic ectodermal dysplasia (HED). It is characterized by hypotrichosis (sparse scalp or body hair), hypodontia (absent or malformed teeth) and hypohidrosis (reduced ability to sweat). Read More
J Craniofac Surg 2018 Dec 10. Epub 2018 Dec 10.
Columbia Presbyterian Medical Center, New York City, NY.
Nasal reconstruction is considered the historic foundation of facial plastic surgery, and the forehead flap remains the workhorse of repair. To recreate both the aesthetic contour and function of the nose, all anatomic layers must be addressed-covering, lining, and structural support. This article reviews the noteworthy history underlying the development of the paramedian forehead flap as the primary tool in reconstruction of large nasal defects while highlighting its implications on modern nasal repair. Read More
Environ Sci Technol 2018 Dec 11. Epub 2018 Dec 11.
Semi-volatile organic compounds (SVOCs) are ubiquitous in the indoor environment and a priority for exposure assessment because of the environmental health concerns that they pose. Direct air-to-skin dermal uptake has been shown to be comparable to the inhalation intake for compounds with certain chemical properties. In this study, we aim to further understand the transport of these types of chemicals through the skin, specifically through the stratum corneum (SC). Read More
Eur Arch Otorhinolaryngol 2018 Dec 5. Epub 2018 Dec 5.
Institut Universitaire de la Face et du Cou, Centre Hospitalier Universitaire de NICE, 31 Avenue de Valombrose, 06100, Nice, Alpes-Maritimes, France.
Introduction: Resections of cutaneous tumors in the medial orbitonasal region can be transfixing. Repairs using a single local flap run the risk of failure and that of secondary sinonasal fistula, especially in cases of surgery on a radiated field. We propose an original and reliable repair procedure using two pedicled regional flaps vascularized by two distinct arterial systems clinched together to reconstruct the mucosal and cutaneous planes. Read More
Open Med (Wars) 2018 24;13:583-596. Epub 2018 Nov 24.
Department of Anaesthesia and Intensive Care Medicine, Innsbruck Medical University, A-6020 Innsbruck, Anichstrasse 35, Innsbruck Austria.
Background: Bispectral index (BIS) monitoring of depth of anesthesia has pioneered the field for more recent monitoring devices like the A-line ARX Index (AAI) or the state (SE) and response entropy (RE) monitoring devices. Following an observational design the present study aimed to simultaneously compare in the same patient recorded BIS, AAI and entropy values.
Methods: Data from patients (n = 32) undergoing minor gynecological operations were analyzed. Read More
Case Rep Oncol 2018 Sep-Dec;11(3):742-750. Epub 2018 Nov 12.
Hematology/Oncology, University of Texas Medical Branch, Galveston, Texas, USA.
Background: Esophageal cancer (EC) with unexpected metastasis (UM) to unusual sites have been increasingly reported. EC with metastasis in general has a very high mortality and morbidity rate, and those with UM to unusual sites present another specific field that needs to be further studied in order to understand and manage the presentation. An extensive systematic review was recently completed regarding this field which identified characteristics and findings concerning patients with EC with UM sites. Read More
J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.
Division of Plastic and Reconstructive Surgery, University of Nebraska Medical Center, Omaha, NE.
Traditional fronto-orbital advancement continues to be a useful operation for correction of craniosynostosis involving the coronal or metopic sutures. Recently, distraction osteogenesis has been used to correct a variety of cranial deformities. Studies have mostly focused on posterior vault distraction due to its simplicity and greater volume gain when compared with anterior vault distraction. Read More
J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.
Department of Plastic Surgery, PGIMER, Chandigarh, India.
The paramedian forehead flap is a workhorse flap for reconstructing the nose and periorbital regions. Many variants are described including an islanded flap. However, eyebrow reconstruction is not usually performed with these flaps. Read More
Int J Occup Saf Ergon 2018 Dec 3:1-27. Epub 2018 Dec 3.
a Service de Santé et de Secours Médical - Health and Medical Rescue Service (SSSM) Service Départemental d'Incendie et de Secours de Maine-et-Loire - Departmental Fire and Rescue Services of Maine-et-Loire (SDIS 49) 6 Avenue du Grand Perigne, 49071 Beaucouzé France ,
This study investigated physiological, cognitive and neuromuscular performances in firefighters after a structural live fire scenario. Changes in vital signs and environmental parameters, cognitive and neuromuscular performance were measured before and after a live-fire training session in a closed environment, in conditions similar to those one could encounter in a structural fire. Very high ambient temperature peaks were reached during the 30 min sessions. Read More
J Paediatr Child Health 2018 Dec;54(12):1397
Paediatric Department, Hospital Tuanku Ja'afar Seremban, Malaysia.
J Paediatr Child Health 2018 Dec;54(12):1394
Paediatric Department, Hospital Tuanku Ja'afar Seremban, Malaysia.
Clin Otolaryngol 2018 Dec 1. Epub 2018 Dec 1.
Royal Berkshire Hospital NHS Foundation Trust, London Road, Reading, RG1 5AN.
Epistaxis is a common presentation to ENT and the use of ice packs is a generally accepted first aid measure. Traditional ice packs on the forehead, bridge of the nose or back of neck can be cumbersome and often requires someone holding onto the ice pack. We describe a simple method to create an ice pack that sits neatly on the nose. Read More
Surg Neurol Int 2018 30;9:215. Epub 2018 Oct 30.
Departement of Pediatric Neurosurgery, Craniofacial Unit, Necker Enfants Malades Hospital, APHP, Paris, France.
Background: Infants with sagittal suture synostosis often present a pathologic dilatation of subarachnoid spaces. The impact of such subarachnoid spaces' enlargement in the morphology of the skull, especially on the forehead and on the surgical outcome, was analyzed.
Methods: Children less than 6 months of age undergoing a surgical correction of the scaphocephaly with Renier's H technique between 2003 and 2008 were included in the study. Read More
Clin Neurol Neurosurg 2018 Nov 26;176:44-46. Epub 2018 Nov 26.
Department of Neurosurgery, Kuala Lumpur Hospital, Malaysia.
Introduction: Dural arteriovenous fistula (dAVF) is a very rare disease characterized by an abnormal vascular communication between arteries and veins in dural mater. It frequently presents with intracranial haemorrhage. Common presenting symptoms are headache and seizures. Read More
Pain Manag 2018 Dec 3. Epub 2018 Dec 3.
Unit of Clinical Biostatistics and Bioinformatics, Aalborg University Hospital North, Aalborg, Denmark.
Aim: Glyceryl trinitrate (GTN) provokes an immediate migraine-like headache, followed by a delayed migraine attack in migraineurs. In healthy volunteers, only an immediate, less severe and shorter headache occurs. The presence of an already sensitized nervous system in migraineurs may underlie the more intense and prolonged GTN-evoked headaches. Read More
QJM 2018 Dec 4. Epub 2018 Dec 4.
Department of Anesthesiology, University at Buffalo, Buffalo, New York.
Brain Inform 2018 Dec 5;5(2):15. Epub 2018 Dec 5.
Department of Life Science and Informatics, Maebashi Institute of Technology, Maebashi, 3710864, Japan.
Background: Although the objective depression evaluation is a hot topic in recent years, less is known concerning developing a pervasive and objective approach for quantitatively evaluating depression. Driven by the Wisdom as a Service architecture, a quantitative analysis method for rating depressive mood status based on forehead electroencephalograph (EEG) and an electronic diary log application named quantitative log for mental state (Q-Log) is proposed. A regression method based on random forest algorithm is adopted to train the quantitative model, where independent variables are forehead EEG features and the dependent variables are the first principal component (FPC) values of the Q-Log. Read More
Front Genet 2018 19;9:554. Epub 2018 Nov 19.
Medical Imaging Research Center, University Hospitals Leuven, Leuven, Belgium.
The human face is a complex trait displaying a strong genetic component as illustrated by various studies on facial heritability. Most of these start from sparse descriptions of facial shape using a limited set of landmarks. Subsequently, facial features are preselected as univariate measurements or principal components and the heritability is estimated for each of these features separately. Read More
J Stomatol Oral Maxillofac Surg 2018 Nov 26. Epub 2018 Nov 26.
Department of Maxillofacial Surgery, Nantes University Hospital, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France.
Fractures of the frontal sinus are classified according to the topography (anterior wall, posterior wall or both), the displacement, and the presence of associated lesions (wound, nasofrontal duct injury, rhinorrhea). Isolated fractures of the anterior wall require surgical management, if the displacement is over 4 mm, to restore the forehead symmetry, to maintain the sinus ventilation and to avoid long-term complications (sinusitis, mucocele, meningitis…). Coronal incision is commonly performed but less invasive techniques are more and more used. Read More
Plast Reconstr Surg 2018 Nov 21. Epub 2018 Nov 21.
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 PLUS Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Rep. of Korea.
Background: The frontalis is a representative target muscle for botulinum neurotoxin type A injections aimed at treating horizontal wrinkles in the forehead region. However, a lack of information regarding the shape and thickness of the frontalis may lead to unexpected side effects.
Methods: This study dissected hemifaces of 44 embalmed Korean and Thai cadavers and performed ultrasound examinations on 20 healthy Korean volunteers. Read More
Musculoskelet Sci Pract 2018 Nov 20;39:45-50. Epub 2018 Nov 20.
Dept. of Radiation Sciences, Radiation Physics and Biomedical Engineering, Umeå University, Umeå, Sweden.
Background: Decreased neck motion and sensorimotor deficits have been identified in those with neck pain. It is thought that these might be related to altered reflex mechanisms between the neck, eyes and the vestibular system. Trunk, head co-ordination might also be altered in neck pain. Read More
J Craniofac Surg 2018 Nov 20. Epub 2018 Nov 20.
Department of Otorhinolaryngology, Dokkyo Medical University Saitama Medical Center.
Pott's puffy tumor (PPT) is a rare, life-threatening complication of frontal sinusitis that is treated with a combination of appropriate antibiotics and surgery for the removal of infected tissue. A 56-year-old man with recurrent forehead swelling was admitted and diagnosed with recurrent PPT. He had undergone endoscopic sinus surgery and pericranial abscess drainage. Read More
J Craniofac Surg 2018 Nov 20. Epub 2018 Nov 20.
Department of Plastic and Reconstructive Surgery, Saitama Children's Medical Center, Saitama, Japan.
Frontonasal dysplasia (FND) is a congenital malformation of the central portion of the face, including the eyes, nose, and forehead. Owing to its rarity and wide spectrum of phenotypes, the optimal timing and technique of surgery remain controversial. Here, we report a case of a patient with FND, who presented with respiratory distress. Read More
Int J Geriatr Psychiatry 2018 Nov 26. Epub 2018 Nov 26.
Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Objectives: The frontal lobe hypothesis of age-related cognitive decline suggests that the deterioration of the prefrontal cortical regions that occurs with aging leads to executive function deficits. Photobiomodulation (PBM) is a newly developed, noninvasive technique for enhancing brain function, which has shown promising effects on cognitive function in both animals and humans. This randomized, sham-controlled study sought to examine the effects of PBM on the frontal brain function of older adults. Read More
J Clin Res Pediatr Endocrinol 2018 Nov 23. Epub 2018 Nov 23.
İnonu University Faculty of Medicine, Department of Radiology, Malatya, Turkey.
Cleidocranial dysplasia (CCD) is a rare congenital autosomal dominant skeletal disorder that is characterized by hypoplasia or aplasia of clavicles, failure of cranial suture closure, dental anomalies, short stature and other changes in skeletal patterning and growth. The gene responsible for pathogenesis has been mapped on the short arm of chromosome 6p21, Core Binding Factor Alpha-1 () or Runt Related Transcription Factor 2 (). Here we describe a CCD patient with a novel mutation in the gene. Read More
J Clin Monit Comput 2018 Nov 22. Epub 2018 Nov 22.
Division of Anesthesiology, Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
In the noninvasive zero-heat-flux (ZHF) method, deep body temperature is brought to the skin surface when an insulated temperature probe with servo-controlled heating on the skin creates a region of ZHF from the core to the skin. The sensor of the commercial Bair-Hugger ZHF device is placed on the forehead. According to the manufacturer, the sensor reaches a depth of 1-2 cm below the skin. Read More
Hautarzt 2018 Nov 22. Epub 2018 Nov 22.
Klinik für Mund‑, Kiefer- und Gesichtschirurgie, Universitätsklinikum Münster, Waldeyerstr. 30, 48149, Münster, Deutschland.
In the presented case, the resulting defect size after resection of a dermatofibrosarcoma protuberans exceeded the treatment capability with local flaps in the region of the exposed facial skin. Through the use of conventional wound healing in combination with a meshed split-thickness skin graft, plastic aesthetic soft tissue treatment with an aesthetically satisfactory result was possible. Read More
Int Med Case Rep J 2018 2;11:307-312. Epub 2018 Nov 2.
Department of Cardiology,
Background: Mixed connective tissue disease (MCTD; also known as Sharp's syndrome) is a rare autoimmune inflammatory disorder characterized by high titer of U1 ribonucleoprotein (U1RNP) antibody and clinical and serological overlap of systemic lupus erythematosus, systemic sclerosis, and polymyositis. The diagnosis is based on clinical and serological factors in criteria such as Alarcon-Segovia, Khan, Kusakawa, and Sharps. Cardiac disease can be a complication of connective tissue disease (CTD). Read More
Ann Plast Surg 2019 Jan;82(1S Suppl 1):S59-S65
Craniofacial Research Center, Craniofacial Surgery, Department of Plastic & Reconstructive Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan.
Background: Augmentative forehead contouring to create a full rounded smooth forehead is increasingly popular worldwide especially in East Asia where a flat and/or concave irregular forehead is considered unaesthetic. We present our outcomes performing fat transfer to the forehead in combination with botulinum toxin (Botox) corrugator-frontalis injection where indicated in East Asians.
Methods: From 2013 to 2017, 62 consecutive patients with flat and/or concave irregular unaesthetic foreheads underwent forehead fat transfer using a microautologous fat transplantation gun. Read More
J Clin Monit Comput 2018 Nov 20. Epub 2018 Nov 20.
Department of Surgical Gastroenterology, Rigshospitalet, Copenhagen University Hospital, Inge Lehmanns Vej 7, 2100, Copenhagen Ø, Denmark.
The mesenteric traction syndrome (MTS) is associated with prostacyclin (PGI) facilitated systemic vasodilatation during surgery and is identified by facial flushing. We hypothesized that severe facial flushing would be related to the highest concentrations of plasma PGI and accordingly to the highest levels of skin blood flow measured by laser speckle contrast imaging (LSCI). Patients scheduled for major upper abdominal surgery were consecutively included. Read More
Ital J Pediatr 2018 Nov 20;44(1):138. Epub 2018 Nov 20.
Division of Pediatric Endocrinology, Meyer University Children's Hospital, University of Florence, Florence, Italy.
Background: Trichorhinophalangeal syndrome (TRPS) is a rare autosomal dominant disorder caused by defects involving the TRPS1 gene. It exhibits distinctive craniofacial, ectodermal and skeletal abnormalities, such as sparse hair, bulbous nasal tip and short deformed fingers, with extremely variable expressivity.
Case Presentation: We report the case of a 17 months old girl, who presented growth retardation and dysmorphic features. Read More
J Thorac Cardiovasc Surg 2018 Dec 28;156(6):2251-2257. Epub 2018 Sep 28.
Department of Cardiovascular Surgery, School of Medicine, Kitasato University, Sagamihara, Japan.
Objectives: High-flow regional cerebral perfusion (HFRCP) provides cerebral and somatic oxygen delivery through collateral vessels during aortic arch repair in small children; however, optimal flow conditions during HFRCP have not been established. We sought to identify markers of peripheral perfusion during HFRCP.
Methods: Between 2009 and 2016, in total 20 consecutive pediatric patients undergoing aortic arch repair with HFRCP were enrolled in this prospective, observational study. Read More
J Biomed Opt 2018 Nov;23(12):1-9
Tufts University, Department of Biomedical Engineering, Medford, Massachusetts, United States.
We report a near-infrared spectroscopy (NIRS) study of coherent hemodynamic oscillations measured on the human forehead at multiple source-detector distances (1 to 4 cm). The physiological source of the coherent hemodynamics is arterial blood pressure oscillations at a frequency of 0.1 Hz, induced by cyclic inflation (to a pressure of 200 mmHg) and deflation of two thigh cuffs wrapped around the subject's thighs. Read More
J Cosmet Dermatol 2018 Nov 15. Epub 2018 Nov 15.
Division of Dental and Maxillofacial Surgery, G.B. Rossi Hospital and Medical University of Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy.
Introduction: We propose a medical filler treatment algorithm of the profile which includes forehead, nose, and chin and to evaluate profilometric results and complications.
Materials And Methods: 83 case reviews of associated liquid forehead, nose, and chin plasty performed consecutively from 2014 to 2016. We monitored the horizontal and vertical sagittal stability into two age group: <40 y. Read More
Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:4363-4366
A Positive Airway Pressure mask was modified to be able to measure the heart rate of the wearer during Positive Airway Pressure (PAP) therapy. The mask was modified by attaching sensors to measure Electrocardiography (ECG) and Photoplethysmography (PPG) signals, from which a heart rate was extracted. The ECG signal was recorded using stainless steel electrodes positioned on the wearer's head and neck. Read More
Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:3639-3641
Estimating blood pressure (BP) from pulse arrival time (PAT) by image-based (skin video) photoplethysmography (iPPG) is of increasing interest due to the non-contact method advantage (over cuff-based methods) and potential for BP measurement to be built into portable devices such as mobile phones. The relationship between pulse transit time extracted from iPPG has been investigated during stable BP. The sensitivity of beat-to-beat iPPG-PAT to dynamic changes in BP has not been explored. Read More
Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:1612-1615
We propose a novel concept for core body temperature estimation to improve sensitivity and specificity of a fever screening system under different environmental conditions based on an infrared thermal camera. The conventional approach of setting low temperature thresholds to determine presence of fever to increase sensitivity has led to highly-degraded specificity due to the low accuracy in core body temperature estimation. Two main causes are the moderate correlation between core body temperature and surface temperature data used to determine it, and the estimation algorithm that does not consider changes in the environment. Read More
Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:1502-1505
The measurement of peripheral oxygen saturation (SpO2) in neonatal intensive care units (NICUs) poses a significant challenge. Motion artifacts due to the patient's limb motion induce many false alarms, which in turn cause an additional workload for the medical staff and anxiety for the parents. We developed a reflectance pulse oximeter dedicated to be placed at the patient's forehead, which is less prone to such artifacts. Read More
Int Med Case Rep J 2018 18;11:271-276. Epub 2018 Oct 18.
Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand,
Background: Horner syndrome refers to a set of clinical presentations resulting from disruption of sympathetic innervation to the eye and adnexa. Classically, the clinical triad consists of ipsilateral blepharoptosis, pupillary miosis, and facial anhidrosis. Ocular sympathetic denervation may signify life-threatening causes. Read More
Brain Dev 2018 Nov 10. Epub 2018 Nov 10.
Institute of Medical Genetics, Tokyo Women's Medical University, Tokyo, Japan; Tokyo Women's Medical University Institute of Integrated Medical Sciences, Tokyo, Japan. Electronic address:
Background: FOXP1 is known as the gene responsible for neurodevelopmental delay associated with language impairment. Broad clinical findings also include feeding difficulty, muscular hypotonia, and distinctive features. These findings are common between patients with loss-of-function mutations in FOXP1 and 3p13 microdeletion involving FOXP1. Read More
Facial Plast Surg Clin North Am 2019 Feb;27(1):85-94
Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, 240 East 38th Street, 14th Floor, New York, NY 10016, USA. Electronic address:
Tissue inelasticity and the hair-bearing nature of the scalp and forehead pose unique challenges during reconstruction. A thorough understanding of the surgical anatomy of the scalp and forehead is paramount for optimal reconstructive outcomes. Primary wound closure is usually preferred over secondary intention healing and skin grafting. Read More
Clin Otolaryngol 2018 Nov 12. Epub 2018 Nov 12.
Department of Otolaryngology, Far Eastern Memorial Hospital, Taipei, Taiwan.
Plast Reconstr Surg 2018 Oct 4. Epub 2018 Oct 4.
Department of Plastic Surgery, Inha University School of Medicine, Incheon, Korea.
Plast Reconstr Surg 2018 Oct 4. Epub 2018 Oct 4.
UT Southwestern Medical Center, Dallas, TX.
Am J Emerg Med 2018 Nov 7. Epub 2018 Nov 7.
Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address:
A ruptured cavernous carotid aneurysm (CCA) with carotid cavernous fistula can appear as a benign headache but progress to a swollen and bloodshot eye overnight. A 66-year-old woman visited emergency department with sudden onset of pain behind her left forehead and vomiting. She was treated for a migraine-like headache and discharged. Read More
World Neurosurg 2018 Nov 8. Epub 2018 Nov 8.
Department of Neurosurgery, Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea. Electronic address:
Objective: To report the outcomes of cranioplasty (CP) with a customized 3dimensional(3D) titanium-mesh plate and identify the relationship between various clinical variables and complications after CP.
Materials And Methods: A total of 20 patients who underwent surgery with customized 3D titanium-mesh plates and were followed-up for more than 6 months from January 2015 to December 2017 were enrolled. Complications related to CP were retrospectively reviewed. Read More
Acta Reumatol Port 2018 Jul-Sep;43(3):235-236
Hospital de Santa Maria.
A 24-day-old female newborn presented with multiple annular erythematous plaques with a targetoid shape, on the forehead, neck and upper trunk, that had begun ten days earlier. She had been diagnosed with citrullinemia type 1 in the first week of life and arginine supplementation was initiated. Her personal and family history was otherwise unremarkable. Read More