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Clin Anat 2019 Jan 10. Epub 2019 Jan 10.

Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, South Korea.

Introduction: Various recently introduced minimally invasive treatment modalities are now widely used for enhancing the aging face. In a special, filler is used to increase the volume of tissue, and so understanding the regional thickness and distribution of the facial superficial fat is essential for optimizing minimally invasive procedures. The aim of this study was to establish the overall facial skin and superficial fat thicknesses using a 3D scanning system. Read More

Plast Reconstr Surg 2019 Jan;143(1):269-271

Sheffield and London, United Kingdom From the Department of Plastic Surgery, Sheffield Teaching Hospitals NHS Foundation Trust; the Departments of Radiology and Plastic Surgery, Guy's and St Thomas' NHS Foundation Trust; and the Department of Anatomy, King's College London.

The paramedian forehead flap is commonly used in nasal reconstruction, and survival of the distal part of the flap is usually essential for a good cosmetic outcome. Venous congestion leading to tissue necrosis is a recognized complication with this flap. The standard paramedian forehead flap is designed with a number of aims. Read More

Plast Reconstr Surg 2018 Nov 21. Epub 2018 Nov 21.

Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 PLUS Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Rep. of Korea.

Background: The frontalis is a representative target muscle for botulinum neurotoxin type A injections aimed at treating horizontal wrinkles in the forehead region. However, a lack of information regarding the shape and thickness of the frontalis may lead to unexpected side effects.

Methods: This study dissected hemifaces of 44 embalmed Korean and Thai cadavers and performed ultrasound examinations on 20 healthy Korean volunteers. Read More

Facial Plast Surg Clin North Am 2019 Feb;27(1):85-94

Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, 240 East 38th Street, 14th Floor, New York, NY 10016, USA. Electronic address:

Tissue inelasticity and the hair-bearing nature of the scalp and forehead pose unique challenges during reconstruction. A thorough understanding of the surgical anatomy of the scalp and forehead is paramount for optimal reconstructive outcomes. Primary wound closure is usually preferred over secondary intention healing and skin grafting. Read More

Proc Natl Acad Sci U S A 2018 11 7;115(47):E11015-E11024. Epub 2018 Nov 7.

Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94720;

Transmission-mode pulse oximetry, the optical method for determining oxygen saturation in blood, is limited to only tissues that can be transilluminated, such as the earlobes and the fingers. The existing sensor configuration provides only single-point measurements, lacking 2D oxygenation mapping capability. Here, we demonstrate a flexible and printed sensor array composed of organic light-emitting diodes and organic photodiodes, which senses reflected light from tissue to determine the oxygen saturation. Read More

Dermatol Surg 2018 11;44 Suppl 1:S2-S4

Department of Dermatology, Carruthers Dermatology Centre, Vancouver, British Columbia, Canada.

Background: Worldwide, the brow is the most common facial site to receive aesthetic treatment. However, the forehead above the brows has been comparatively less well studied with respect to both neuromodulators and fillers. Age-related remodeling of the forehead with loss of facial bone has been demonstrated on detailed radiographic studies. Read More

Aesthet Surg J 2018 Oct 23. Epub 2018 Oct 23.

Malopolska Center for Burns and Plastic Surgery, The Ludwik Rydygier Hospital, Krakow, Poland.

Background: The superficial temporal artery (STA) is a terminal branch of the external carotid artery, which supplies multiple regions of the scalp and face. Reconstructive and aesthetic procedures are important clinical aspects of STA supply.

Objectives: The aim of this study was to develop an anatomical map of the STA related to anatomical landmarks. Read More

Forensic Sci Int 2018 Nov 26;292:212-223. Epub 2018 Sep 26.

Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Viničná 7, 128 43 Prague, Czech Republic.

Correlations between facial bony structures and soft facial features are fundamental for facial approximation methods The purpose of this study was to assess the strength of the association between craniofacial shape and the shape of the soft-tissue profile and to determine the extent to which it might be possible to predict the latter from the former. Soft-tissue and skeletal facial profile curves were extracted from 86 lateral head cephalograms of a recent Central European population (52 males and 34 females, aged between 19 and 43 years), divided into five parts, segmented automatically and evaluated using geometric morphometrics. The magnitude of the hard-soft shape association was assessed by principal component analysis and subsequent multiple linear regression (Halazonetis, 2007), by partial least square analysis (PLS) (Rohlf and Corti, 2000) and the RV coefficient (Klingenberg, 2009). Read More

J Clin Neurosci 2018 Dec 16;58:218-221. Epub 2018 Oct 16.

Department of Neurosurgery, Peking University International Hospital, Peking University Health Science Center, Beijing 102206, PR China; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, PR China; China National Clinical Research Center for Neurological Diseases, Beijing 100050, PR China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing 100050, PR China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, PR China. Electronic address:

Dural cavernous angiomas (CAs) outside the middle cranial fossa are uncommon vascular lesions that generally present with benign clinical course compared to those within the middle cranial fossa. Aggressive invasion of these lesions is less common and mainly involves the skull. Dura sinus invasion and diffused nodular growth are exceedingly rare. Read More

Medicine (Baltimore) 2018 Oct;97(42):e12676

Department of Interventional Radiology and hemangioma.

Intra-arterial chemotherapy (IAC) has become an essential technique for the management of advanced intraocular retinoblastoma (RB). In this study, the aim of this article is to describe the clinical results and the short-term complications of IAC performed in our hospital.We retrospectively analyzed patients with newly diagnosed unilateral advanced intraocular (group D or E) RB undergoing IAC from October 2016 to December 2017 in our hospital. Read More

J Craniofac Surg 2018 Nov;29(8):2234-2236

Plastic Reconstructive and Aesthetic Surgery Department, Showa University School of Medicine, Tokyo, Japan.

Half-nose or heminasal aplasia is an extremely rare congenital malformation, which has a withering effect both on the patient and the family. Proboscis lateralis is a rare facial anomaly resulting in the incomplete development of one side of the nose, which was first defined in 1861 by Forster in his monograph. Proboscis lateralis, cleft nose, and nasal agenesis are rare anomalies; however, half-nose is also an extremely rare condition. Read More

Facial Plast Surg 2018 Oct 8;34(5):466-473. Epub 2018 Oct 8.

Division of Facial Plastic Surgery, Advanced Facial Plastic Surgery Center, Dallas, Texas.

The periorbital and forehead regions are among the most expressive parts of the face. A thorough understanding of the complex facial anatomy and aesthetic norms are essential when evaluating and treating a patient for facial brow rejuvenation. Not only will knowledge of the anatomy enhance facial injection and surgical outcomes, but will also diminish potential complications. Read More

J Craniofac Surg 2018 Nov;29(8):2186-2191

Department of Oral and Maxillofacial Surgery, University of Lille, CHU Lille.

In this study, the authors aimed to describe orocraniofacial features and to suggest orthodontic-surgical managements in achondroplasia, based on a literature review. The authors focused on skeletal and dentoalveolar malocclusion in order to highlight the place of orthognathic surgery, based on our experience of 3 patients. Maxillary hypoplasia in achondroplasia typically results in an Angle class III malocclusion with an anterior open bite. Read More

J Craniofac Surg 2018 Nov;29(8):e785-e790

Department of Dermatology, Huashan Hospital affiliated of Fudan University.

Background: The incidence of hair loss among Chinese male has increased to 21.3 per hundred. Hair restoration has been an effective technique. Read More

World Neurosurg 2018 Dec 27;120:525-529. Epub 2018 Sep 27.

Department of Pediatric Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Brian Tumor, Beijing, People's Republic of China. Electronic address:

Background: Intraosseous lipomas occurring within the skull are rare. Currently, the known locations include the frontal bone, parietal bone, temporal bone, and ethmoid bone. Thus far, we have found only 12 cases of lipoma at the top of the forehead on the skull, and only 2 cases of recurrent intraosseous lipoma have been reported. Read More

J Craniofac Surg 2018 Oct;29(7):e726-e727

Department of Auricular Reconstruction, Plastic Surgery Hospital, Peking Union Medical College, Beijing, China.

Skin necrosis is a rare but severe potential complication after injection of hyaluronic acid (HA). Based on the understanding of the causes and mechanisms of this complication, many precautions have been proposed. Still, this adverse reaction happened from time to time. Read More

Aesthetic Plast Surg 2018 Dec 19;42(6):1531-1539. Epub 2018 Sep 19.

Department of Plastic Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Background: Super-high superficial musculoaponeurotic system (SMAS) suspension and tailor tack plication are powerful facelift tools used in cases of primary facial rhytidectomy.

Technique: Thorough pre-operative patient screening and counseling are completed in an outpatient cosmetic surgery center. A super-high SMAS flap is developed by undermining and incising along a line extending from the tragus to lateral canthus and dissecting the SMAS sufficiently to induce movement of the lateral nose and the oral commissure with traction on the SMAS. Read More

J Craniofac Surg 2018 Oct;29(7):1928-1933

School of Ethnology and Sociology, Minzu University of China, Beijing.

Much research has been conducted on the morphological characteristics of the Chinese. However, very few facial measurements have been documented, especially of the side face. This study uses geometirc morphometric method to analyze the contour and variations of the side face in Bai and Yi ethnic minorities from Yunnan province, China. Read More

J Hum Genet 2018 Nov 4;63(11):1189-1193. Epub 2018 Sep 4.

Department of Paediatrics, University of Szeged, Szeged, Hungary.

Heterozygous disruptions in FOXP1 are responsible for developmental delay, intellectual disability and speech deficit. Heterozygous germline PTCH1 disease-causing variants cause Gorlin syndrome. We describe a girl with extreme megalencephaly, developmental delay and severe intellectual disability. Read More

Pediatr Dermatol 2018 Nov 31;35(6):e363-e365. Epub 2018 Aug 31.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Parry-Romberg syndrome (PRS) is characterized by progressive atrophy of facial skin, soft tissues, muscle, and bone. En coup de sabre syndrome is a form of linear scleroderma (LS) involving the skin of the frontoparietal forehead and scalp. Both conditions can be associated with neurologic findings, including seizures. Read More

Acupunct Med 2018 Dec 29;36(6):408-414. Epub 2018 Aug 29.

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China.

Objectives: To compare the neural pathways associated with the tissues located at different traditional acupuncture points in the rat forehead and face using the cholera toxin B subunit (CTB) neural tracing technique.

Methods: After injection of CTB into the tissues at GB14, ST2 and ST6 in the rat, the neural labelling associated with each acupuncture point was revealed by fluorescent immunohistochemistry of the nervous system, including the trigeminal ganglion (TRG), cervical dorsal root ganglia (DRG), spinal cord and brain.

Results: The CTB labelling included sensory neurons and their transganglionic axonal terminals, as well as motor neurons. Read More

J Craniofac Surg 2018 Oct;29(7):e682-e684

Division of Plastic, Aesthetic, and Reconstructive Surgery, DeWitt-Daughtry Family Department of Surgery.

Head banging is a commonly observed movement disorder which is typically self-limited. Complications secondary to this behavior are rare. In this report, the authors present the case of a 15-year-old patient who was treated for a forehead mass which developed secondary to chronic head banging. Read More

An Bras Dermatol 2018 Sep-Oct;93(5):659-664

Graduate School of Design, National Yunlin University of Science and Technology, Yunlin County, Taiwan.

Background: Facial threading involves the removal of hairs to restore facial skin smoothness. However, its effectiveness has not been rigorously evaluated.

Objective: To evaluate effects of facial threading on skin roughness, hydration, melanin index, and vellus hair on the face, complemented by a subjective evaluation of the tactile feel of the skin and improvement in skin color. Read More

Plast Reconstr Surg 2018 09;142(3):334e-341e

Dallas and El Paso, Texas From The Craniofacial Center; the Department of Research, Medical City Dallas Hospital; and the Department of Surgery, Texas Tech University Health Sciences Center of El Paso.

Background: Following correction of anterior sutural fusions, long-term forehead irregularities may arise. Based on the premise that frontal reconstructions using a seamless construct might produce better long-term aesthetic results, the supraorbital bandeau was abandoned for a single-piece frontal reconstruction. The purpose of this review was to compare outcomes and complications between children who underwent reconstruction with the traditional supraorbital bandeau and those who underwent reconstruction with a single bony segment. Read More

J Cosmet Dermatol 2018 Aug 26. Epub 2018 Aug 26.

Department of Dermatology and Cutaneous Biology Research Center, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.

Background: Transcutaneous pneumatic injection (TPI) is a minimally invasive, needle-free modality that can be used to forcefully deliver solution into soft tissues of the face and scalp.

Objective: To evaluate the effects of TPI of 5% isotonic and 20% hypertonic glucose solutions in in vivo human skin for face lifting.

Methods And Materials: A prospective, split-face, evaluator-blinded comparison study was performed on 10 Korean participants who were treated with three sessions of TPI using 5% isotonic and 20% hypertonic glucose solutions. Read More

J Cosmet Dermatol 2018 Dec 26;17(6):1031-1036. Epub 2018 Aug 26.

Area88 Plastic Surgery Clinic, Seoul, Korea.

Background: Color Doppler ultrasound has a potential role as an imaging guide in aiding filler injections which are blinded procedures.

Objective: This study investigated the forehead arteries and provided insight into their anastomoses. This was performed by challenging their function to provide blood through these anastomoses when the main artery was temporary occluded by compression. Read More

Eur J Dermatol 2018 Jun;28(3):343-350

Associate professor, Department of Dermatology, FMB-Unesp, São Paulo Brazil.

Background: Adapalene has been previously evaluated as a treatment for actinic keratosis (AK) and solar lentigines and shown to improve signs of photoaging.

Objectives: To evaluate whether adapalene 0.3% gel is non-inferior to tretinoin 0. Read More

Anal Bioanal Chem 2018 Oct 4;410(25):6517-6528. Epub 2018 Aug 4.

Lip(Sys)2- Chimie Analytique Pharmaceutique (FKA EA4041 Groupe de Chimie Analytique de Paris-Sud), University Paris-Sud 11, Université Paris-Saclay, 5 rue Jean Baptiste Clément, 92290, Châtenay-Malabry, France.

After life in utero and birth, the skin is submitted to an important process of adaptation to a relatively dry gaseous environment. Skin surface lipids (SSLs) contribute actively to the protection of the skin barrier. Within this context, our objective was to study the evolution of each lipid compound during the postnatal period. Read More

Dermatology 2018 31;234(3-4):99-104. Epub 2018 Jul 31.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

Background: Skin cancer removal surgery involving the tip or dorsum of the nose often results in large-sized defects with exposure of cartilage. In such cases, the paramedian forehead flap is a frequently used reconstruction technique; however, this method is complex and can result in a cosmetically unsatisfying outcome.

Objective: To describe the folded transposition flap as an aesthetically pleasing alternative to the paramedian forehead flap for large nasal defects with exposed cartilage. Read More

Cutis 2018 Jun;101(6):E19-E21

Division of Dermatology, Center for Dermatologic and Cosmetic Surgery, Washington University in St. Louis, Missouri, USA.

We present a case of a 72-year-old man who was found to have intravascular invasion during Mohs micrographic surgery (MMS) of cutaneous squamous cell carcinoma (cSCC) on the left side of the forehead. The patient was subsequently treated with adjuvant radiation without evidence of disease recurrence. We present a case review to discuss treatment options for high-risk features of cSCC with the aim to assist in treatment guidelines. Read More

Med Arch 2018 Jun;72(3):227-229

Anaesthesiological Clinic, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens-Greece.

Introduction: Superficial temporal artery aneurysms (STAAs) occur in 1% of arterial aneurysms; mostly (95%) are pseudoaneurysms following trauma; true aneurysms are rare (5%); forty-five cases are reported.

Aim: To report a rare case of a congenital STAAA.

Case Report: A67-year-old patient recalled the existence of a true-histologically evidenced- aneurysm of the right superficial temporal artery since his childhood denying any head injury; it was resected through a horizontal skin incisure. Read More

Pediatr Dermatol 2018 Sep 18;35(5):575-581. Epub 2018 Jul 18.

Department of Dermatology, Eastern Health, Monash University, Melbourne, Vic., Australia.

Background: There is a lack of consensus regarding how best to screen children with facial port-wine stains for Sturge-Weber syndrome. Many favor brain magnetic resonance imaging, and adjunctive electroencephalography is increasingly used. However, the sensitivity, specificity, and negative and positive predictive value of magnetic resonance imaging and electroencephalography and whether screening improves seizure recognition is unclear. Read More

J Cosmet Dermatol 2018 Oct 13;17(5):712-718. Epub 2018 Jul 13.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Hyaluronic acid (HA) injection is a popular nonsurgical, facial rejuvenating procedure. Due to the rapidly expanding use of HA injections, significant potential complications have also increased in frequency. Among these complications, the rare but most devastating one is arterial occlusion, which can result in skin necrosis or blindness. Read More

J Drugs Dermatol 2018 Jul;17(7):804-806

We present the case of a man that had a rapidly growing nodule on his face. Removal of the lesion was more difficult than anticipated because it was tightly adherent to adjacent tissue. Pathology from the lesion showed a malignant neoplasm thought to have arisen at a distant site. Read More

Medicine (Baltimore) 2018 Jul;97(28):e11283

Department of Dermatology.

Rationale: Frontometaphyseal dysplasia (FMD) is a dominant X-linked rare disease caused by mutations of FLNA. The distinctive features of FMD include skeletal dysplasia, facial dysmorphism, extremities anomalies, deafness, cleft palate and eye anterior segment anomalies, yet none of the complications, such as acro-osteolysis, keratitis, xerosis or poikiloderma, have been reported in FMD.

Patient Concerns: A 29-year-old mother and her 7-year-old daughter, both presented with congenital glaucoma, craniofacial dysmorphism, xerosis and poikiloderma, were admitted to our hospital in 2011. Read More

Clinics (Sao Paulo) 2018 07 2;73:e324. Epub 2018 Jul 2.

Unidade de Genetica, Instituto da Crianca (ICR), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Objectives: To characterize the natural history of 39 achondroplastic patients diagnosed by clinical, radiological and molecular assessments.

Methods: Observational and retrospective study of 39 patients who were attended at a public tertiary level hospital between 1995 and 2016.

Results: Diagnosis was made prenatally in 11 patients, at birth in 9 patients and within the first year of life in 13 patients. Read More

Rom J Morphol Embryol 2018 ;59(1):345-352

Department of Plastic Surgery and Reconstructive Microsurgery, Emergency Clinical Hospital of Bucharest, Romania;

The risk of developing basal cell carcinoma (BCC) during lifetime varies between 29-55%, while for squamous cell carcinoma (SCC) varies between 7-11%. Between them, considered to be a BCC, there is a particular histological type, named metatypical basal cell carcinoma (MTC) or basosquamous cell carcinoma (BSCC). In this paper, we presented a rare case of metatypical carcinoma of the forehead with an interesting history of unexpected recurrences, underlining the clinical, therapeutic and histological essential aspects that may come in use to other clinicians in managing this type of cancer. Read More

Dermatol Surg 2018 11;44(11):1421-1426

All authors are affiliated with the Department of Oral & Maxillofacial Surgery, Qilu Hospital, and Institute of Stomatology, Shandong University, Jinan, China.

Background: Foam sclerotherapy is an effective treatment strategy for venous malformations (VMs). Stability is one of the characteristics of sclerosant foams that determine the sclerosing power.

Objective: To evaluate the clinical outcomes of sclerotherapy with prolonged half-life of hyaluronic acid (HA)-polidocanol (POL) foam for treating head and neck VMs. Read More

J Craniofac Surg 2018 Nov;29(8):2032-2037

Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

The goal of nasal reconstruction surgery is to restore normal nasal shape and function, and its success begins with creating a stable framework. In this article the authors discuss the most advantageous materials for building such a framework and how to design this element to achieve better and more durable outcomes. This is a retrospective study including patients who underwent nasal reconstruction in our rhinoplasty and nasal reconstruction center at a tertiary referral hospital between 2006 and 2016. Read More

J Craniofac Surg 2018 Oct;29(7):2005

Department of Plastic Surgery, Inha University School of Medicine, Incheon, Korea.

J Craniofac Surg 2018 Sep;29(6):1558-1561

The Third Department, Plastic Surgery Hospital, Peking Union Medical College and the Chinese Academy of Medical Sciences, Beijing, China.

Forehead aging is characterized by wrinkles, loss of skin elasticity, brow ptosis, and soft-tissue atrophy. For patients with prominent rhytids and marked brow ptosis, forehead lift is still the most effective treatment with a persisting result. In order to eliminate the glabellar wrinkles, forehead lift usually requires the removal of the corrugator supercilii muscle and procerus, which can lead to glabellar flattening or depression. Read More

PLoS One 2018 31;13(5):e0197738. Epub 2018 May 31.

Department of Behavioral Ecology, University of Goettingen, Goettingen, Germany.

Objectives: Previous research has documented associations of physical strength and facial morphology predominantly in men of Western societies. Faces of strong men tend to be more robust, are rounder and have a prominent jawline compared with faces of weak men. Here, we investigate whether the morphometric patterns of strength-face relationships reported for members of industrialized societies can also be found in members of an African pastoralist society, the Maasai of Northern Tanzania. Read More

Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4):e124-e127

Department of Ophthalmology, Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, U.S.A.

Linear scleroderma en coup de sabre with ophthalmic findings has been previously described in the literature on numerous occasions. A 57-year-old woman presented with focal trichiasis secondary to tarsal thinning, adjacent to a linear brow and forehead deformity consistent with linear scleroderma en coup de sabre. Cases of linear scleroderma en coup de sabre involving the eyelids have been reported, most often with madarosis, ptosis, or skin atrophy; however, to the authors' knowledge, this is the first reported case of linear scleroderma associated with trichiasis and involvement of the deeper eyelid tissues, particularly the tarsus. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Nov;31(22):1753-1755

Department of Otolaryngology Head and Neck Surgery, Shandong People's Armed Police Corps Hospital, Jinan, 250014, China.

To observed the application of expanded pedicle forehead flap in nasal defect. Totally 11 whole nasal defect cases in our department from June 2010 to March 2016 were treated with the expanded pedicle forehead flap. Regular follow-up was performed after operation to observe the survival condition of flaps, shape, color, texture and scar in donor site after nasal repair. Read More

Forensic Sci Int 2018 Jul 16;288:236-241. Epub 2018 May 16.

Sezione di Medicina Legale - Università degli Studi di Torino, Italy.

Geberth in 2006 stated that "staging is a conscious criminal action on the part of an offender to thwart an investigation." In the present paper two crime scenes staged by handling digital evidence are reported. The first case involves a 50-year-old woman who had been living with the offender for three years before he murdered her at the end of their relationship. Read More

Acta Dermatovenerol Croat 2018 Apr;26(1):73-74

Vladimir Prelević, MD, Clinic for Nephrology Clinical Center of Montenegro, Ljubljanska bb 81101 Podgorica, Montenegro;

Dear Editor, Tuberous sclerosis (TS) is an autosomal dominant multisystem disease, which occurs due to genetically determined hyperplasia of ectodermal and mesodermal cells. Clinical manifestations present on the skin and in the nervous system, kidneys, heart, and other organs. Recent studies estimate the incidence of TS at 1/6000 to 1/10,000 live births, and a prevalence in the general population of approximately 1 in 20,000 (1). Read More

Kurume Med J 2018 Jul 21;64(4):91-95. Epub 2018 May 21.

Department of Pediatrics, National Hospital Organization Tokyo Medical Center.

The oropharynx is examined by focusing an electric light, penlight, or forehead mirror on a desired visual field using a tongue depressor. However, it is extremely difficult to obtain objective recorded evidence for display with these methods, and the tools for examination have remained virtually unchanged for the past century. Treatment of the pharynx/oral cavity is exceedingly difficult, particularly in elderly patients and children. Read More

Am J Dermatopathol 2018 Aug;40(8):575-579

Department of Pathology, Section of Dermatopathology, University of Virginia Health System, Charlottesville, VA.

Sclerosing squamous cell carcinoma (SCC), also known as "desmoplastic" SCC, is a rare subtype of cutaneous malignancy. This variant is clinically significant because it is associated with an increased risk of local recurrence and metastasis. We herein present 16 examples of sclerotic SCC of the skin in 8 men and 3 women, with a median age of 66 years. Read More

Skin Res Technol 2018 Nov 8;24(4):656-662. Epub 2018 May 8.

Institute of Dermatology and Department of Dermatology at NO.1 Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.

Background: Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant.

Objective: The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. Read More